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  1. Recommendations for reporting findings from analyses using artificial intelligence and machine learning in the Journal of Alzheimer's Disease

    Article • Journal of Alzheimer’s Disease, January 2026, SAGE Publications

    Professor Paula I. Moreira, Professor George Perry

  2. Alzheimer’s disease: diabetes of the brain

    Article • January 2026, Elsevier

    Professor Paula I. Moreira

  3. Lipid droplet dysmetabolism affects cell homeostasis in an in vitro model of Alzheimer’s disease

    Article • June 2025, openRxiv

    Professor Paula I. Moreira

  4. Therapeutic Trials in Alzheimer’s Disease: Where Are We Now?

    Article • Journal of Alzheimer’s Disease, October 2024, IOS Press

    Professor Paula I. Moreira

  5. Fueling Alzheimer’s Disease: Where Does Immunometabolism Stand?

    Article • Journal of Alzheimer’s Disease, August 2024, IOS Press

    Sónia Correia, Professor Paula I. Moreira, Professor George Perry

  6. MitoTempo protects against nε-carboxymethyl lysine-induced mitochondrial dyshomeostasis and neuronal cells injury

    Article • Free Radical Biology and Medicine, August 2024, Elsevier

    Professor Paula I. Moreira

  7. Protective effects of 2,4-dinitrophenol in okadaic acid-induced cellular model of Alzheimer's disease

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2024, Elsevier

    Professor Paula I. Moreira

  8. Corrigendum: Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease

    Article • Frontiers in Aging Neuroscience, May 2024, Frontiers

    Professor Paula I. Moreira

  9. Mapping the lipidome in mitochondria‐associated membranes (MAMs) in an in vitro model of Alzheimer's disease

    Article • Journal of Neurochemistry, February 2024, Wiley

    Professor Paula I. Moreira

  10. Neuro–glia communication and glycolysis

    Article • January 2024, Elsevier

    Professor Paula I. Moreira

  11. Current Advances in Mitochondrial Targeted Interventions in Alzheimer’s Disease

    Article • Biomedicines, August 2023, MDPI AG

    Professor Paula I. Moreira

  12. Therapeutic potential of glutaminyl cyclases: Current status and emerging trends

    Article • Drug Discovery Today, May 2023, Elsevier

    Professor Paula I. Moreira

  13. Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease

    Article • Frontiers in Aging Neuroscience, April 2023, Frontiers

    Professor Paula I. Moreira

  14. Retinal imaging in animal models: Searching for biomarkers of neurodegeneration

    Article • Frontiers in Ophthalmology, April 2023, Frontiers

    Professor Paula I. Moreira, Professor António Miguel Morgado

  15. Metabolic defects shared by Alzheimer's disease and diabetes: A focus on mitochondria

    Article • Current Opinion in Neurobiology, April 2023, Elsevier

    Professor Paula I. Moreira

  16. A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative Diseases

    Article • Biology, March 2023, MDPI AG

    Professor Paula I. Moreira

  17. Disrupted cellular quality control mechanisms in aging

    Article • January 2023, Elsevier

    Professor Paula I. Moreira

  18. Longitudinal OCT texture analysis to assess the retinal changes in the triple‐transgenic mouse model of Alzheimer's disease

    Article • Acta Ophthalmologica, December 2022, Wiley

    Professor Paula I. Moreira

  19. WWOX inhibition by Zfra1-31 restores mitochondrial homeostasis and viability of neuronal cells exposed to high glucose

    Article • Cellular and Molecular Life Sciences, August 2022, Springer Science + Business Media

    Professor Paula I. Moreira

  20. Stage-independent biomarkers for Alzheimer’s disease from the living retina: an animal study

    Article • Scientific Reports, August 2022, Springer Science + Business Media

    Professor Paula I. Moreira

  21. Type 2 Diabetes Induces a Pro-Oxidative Environment in Rat Epididymis by Disrupting SIRT1/PGC-1α/SIRT3 Pathway

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Professor Paula I. Moreira

  22. Retinal Aging in 3× Tg-AD Mice Model of Alzheimer's Disease

    Article • Frontiers in Aging Neuroscience, June 2022, Frontiers

    Professor Paula I. Moreira

  23. Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria

    Article • Antioxidants & Redox Signaling, May 2022, Mary Ann Liebert Inc

    Professor Paula I. Moreira, Professor George Perry

  24. ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

    Article • Cellular and Molecular Life Sciences, March 2022, Springer Science + Business Media

    Professor Paula I. Moreira

  25. Insulin-Induced Recurrent Hypoglycemia Up-Regulates Glucose Metabolism in the Brain Cortex of Chemically Induced Diabetic Rats

    Article • International Journal of Molecular Sciences, December 2021, MDPI AG

    Professor Paula I. Moreira

  26. Targeting Mitochondria and Redox Dyshomeostasis in Brain Ageing: An Update

    Article • December 2021, Springer Science + Business Media

    Professor Paula I. Moreira

  27. Oxygen Sensing and Signaling in Alzheimer’s Disease: A Breathtaking Story!

    Article • Cellular and Molecular Neurobiology, September 2021, Springer Science + Business Media

    Professor Paula I. Moreira

  28. Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer’s Disease

    Article • Biomedicines, July 2021, MDPI AG

    Professor Paula I. Moreira

  29. Longitudinal normative OCT retinal thickness data for wild-type mice, and characterization of changes in the 3×Tg-AD mice model of Alzheimer's disease

    Article • Aging, April 2021, Impact Journals, LLC

    Professor Paula I. Moreira

  30. WWOX: A New Therapeutic Target In Type 2 Diabetes-Associated Neurodegeneration

    Article • Metabolism, March 2021, Elsevier

    Professor Paula I. Moreira

  31. Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer’s Disease

    Article • Molecular Neurobiology, February 2021, Springer Science + Business Media

    Professor Paula I. Moreira

  32. IGF1R Deficiency Modulates Brain Signaling Pathways and Disturbs Mitochondria and Redox Homeostasis

    Article • Biomedicines, February 2021, MDPI AG

    Professor Paula I. Moreira

  33. Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer’s Disease

    Article • International Journal of Molecular Sciences, January 2021, MDPI AG

    Professor Paula I. Moreira

  34. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Article • Autophagy, January 2021, Taylor & Francis

    MD, PhD Pierre-Louis Tharaux, Joilson O. Martins, Dr. rer. nat. Marc Herb, Dr Marcia R Cominetti, Alessio Di Fonzo, Christoph Gerhardt, Dr Mustafa Sahin, Dr Cinzia Volonté, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Prof Robert Bryson-Richardson, Professor Hyun Kyu Song, Prof Claudia Cavadas, Professor Po Sing Leung, Paula Ludovico, Javeed Shah, Prof. Dr. Giovanni Di Guardo, Dr Takeshi Noda, Professor Tullio Florio, Professor Kevin Coombs, Ning Chen, Maria Vaccaro, Dr Jorge F Quarleri, Professor hengyi xiao, Dr. Yanzhuang Wang, Prof Giacinto Bagetta, Dr. Ann M Wehman, Dr Pawan Sharma, Dr Anna Krasnodembskaya, Dr Francesca Finetti, Nicoletta Filigheddu, Professor Javier González-Gallego, Professor Günther Weindl, Professor Nektarios Tavernarakis, Jie Chao

  35. PINK1/PARKIN signalling in neurodegeneration and neuroinflammation

    Article • Acta Neuropathologica Communications, November 2020, Springer Science + Business Media

    Professor Paula I. Moreira

  36. Associations between Trace Elements and Cognitive Decline: An Exploratory 5-Year Follow-Up Study of an Elderly Cohort

    Article • International Journal of Environmental Research and Public Health, August 2020, MDPI AG

    Professor Paula I. Moreira

  37. Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

    Article • Nature Reviews Drug Discovery, July 2020, Springer Science + Business Media

    Professor Paula I. Moreira

  38. Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do Mitochondria-Associated Membranes (MAMs) play a role?

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, June 2020, Elsevier

    Professor Paula I. Moreira

  39. Characterization of the retinal changes of the 3×Tg-AD mouse model of Alzheimer’s disease

    Article • Health and Technology, April 2020, Springer Science + Business Media

    Professor Paula I. Moreira

  40. Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 Inhibitors

    Article • Biomolecules, April 2020, MDPI AG

    Professor Paula I. Moreira

  41. Liraglutide Protects Against Brain Amyloid-β1–42 Accumulation in Female Mice with Early Alzheimer’s Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation

    Article • International Journal of Molecular Sciences, March 2020, MDPI AG

    Professor Paula I. Moreira

  42. The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice

    Article • Free Radical Biology and Medicine, January 2020, Elsevier

    Professor Paula I. Moreira

  43. Antidiabetic drugs for Alzheimer's and Parkinson's diseases: Repurposing insulin, metformin, and thiazolidinediones

    Article • January 2020, Elsevier

    Professor Paula I. Moreira

  44. Cognitive Impairment in Obesity and Diabetes

    Article • January 2020, Springer Science + Business Media

    Professor Paula I. Moreira

  45. An overview of glutaminyl cyclase inhibitors for Alzheimer’s disease

    Article • Future Medicinal Chemistry, December 2019, Future Science

    Professor Paula I. Moreira

  46. Retinal thickness of the triple‐transgenic mice model of Alzheimer\’s disease at the age of one month

    Article • Acta Ophthalmologica, December 2019, Wiley

    Professor Paula I. Moreira

  47. Is Alzheimer’s disease an inflammasomopathy?

    Article • Ageing Research Reviews, December 2019, Elsevier

    Professor Paula I. Moreira

  48. Links between Cognitive Status and Trace Element Levels in Hair for an Environmentally Exposed Population: A Case Study in the Surroundings of the Estarreja Industrial Area

    Article • International Journal of Environmental Research and Public Health, November 2019, MDPI AG

    Professor Paula I. Moreira

  49. Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer’s disease: a longitudinal multimodal in vivo study

    Article • Alzheimer s Research & Therapy, November 2019, Springer Science + Business Media

    Professor Paula I. Moreira

  50. Characterization of the Retinal Changes of the 3xTg-AD Mouse Model of Alzheimer’s Disease

    Article • September 2019, Springer Science + Business Media

    Professor Paula I. Moreira

  51. Post-translational modifications in brain health and disease

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2019, Elsevier

    Professor Paula I. Moreira

  52. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2019, Elsevier

    Professor Paula I. Moreira, Professor George Perry

  53. Diabesity and brain disturbances: A metabolic perspective

    Article • Molecular Aspects of Medicine, April 2019, Elsevier

    Professor Paula I. Moreira

  54. A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss

    Article • Human Molecular Genetics, February 2019, Oxford University Press (OUP)

    Professor Paula I. Moreira

  55. The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer’s Disease: Critical Aspects to Unravel

    Article • Molecular Neurobiology, January 2019, Springer Science + Business Media

    Professor Paula I. Moreira

  56. Tortuous Paths of Insulin Signaling and Mitochondria in Alzheimer’s Disease

    Article • January 2019, Springer Science + Business Media

    Professor Paula I. Moreira

  57. Can the retina show similar molecular and cellular changes as the brain in an animal model of Alzheimer’s disease?

    Article • Frontiers in Cellular Neuroscience, January 2019, Frontiers

    Professor Paula I. Moreira

  58. O-GlcNAcylation and neuronal energy status: Implications for Alzheimer’s disease

    Article • Ageing Research Reviews, September 2018, Elsevier

    Professor Paula I. Moreira

  59. Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events

    Article • Frontiers in Physiology, July 2018, Frontiers

    Professor Paula I. Moreira

  60. Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease

    Article • Neuropharmacology, July 2018, Elsevier

    Professor Paula I. Moreira

  61. Preface

    Article • Journal of Alzheimer’s Disease, June 2018, IOS Press

    Professor George Perry, Professor Paula I. Moreira

  62. Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington’s Disease

    Article • Scientific Reports, June 2018, Springer Science + Business Media

    Professor Paula I. Moreira

  63. Highlights in BACE1 Inhibitors for Alzheimer's Disease Treatment

    Article • Frontiers in Chemistry, May 2018, Frontiers

    Professor Paula I. Moreira

  64. Beneficial effects of white wine polyphenols-enriched diet on Alzheimer’s disease-like pathology

    Article • The Journal of Nutritional Biochemistry, May 2018, Elsevier

    Professor Paula I. Moreira

  65. The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy

    Article • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, April 2018, Elsevier

    Professor Paula I. Moreira

  66. Sweet Mitochondria: A Shortcut to Alzheimer’s Disease

    Article • Journal of Alzheimer’s Disease, March 2018, IOS Press

    Professor Paula I. Moreira

  67. Fingernail Trace Element Content in Environmentally Exposed Individuals and Its Influence on Their Cognitive Status in Ageing

    Article • Exposure and Health, March 2018, Springer Science + Business Media

    Professor Paula I. Moreira

  68. Uncoupling Protein 2 Inhibition Exacerbates Glucose Fluctuation-Mediated Neuronal Effects

    Article • Neurotoxicity Research, September 2017, Springer Science + Business Media

    Professor Paula I. Moreira

  69. Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats

    Article • Molecular Neurobiology, June 2017, Springer Science + Business Media

    Professor Paula I. Moreira

  70. Insights into the human brain proteome: Disclosing the biological meaning of protein networks in cerebrospinal fluid

    Article • Critical Reviews in Clinical Laboratory Sciences, April 2017, Taylor & Francis

    Professor Paula I. Moreira

  71. Human predisposition to cognitive impairment and its relation with environmental exposure to potentially toxic elements

    Article • Minerals and the Environment, March 2017, Springer Science + Business Media

    Professor Paula I. Moreira

  72. Diabesity and Brain Energy Metabolism: The Case of Alzheimer’s Disease

    Article • January 2017, Springer Science + Business Media

    Professor Paula I. Moreira

  73. Mitochondria in Alzheimer’s Disease and Diabetes-Associated Neurodegeneration: License to Heal!

    Article • January 2017, Springer Science + Business Media

    Professor Paula I. Moreira

  74. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology

    Article • Journal of Alzheimer’s Disease, November 2016, IOS Press

    Frederick P Bellinger, Professor George Perry, Professor Paula I. Moreira

  75. Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology

    Article • Molecular Neurobiology, October 2016, Springer Science + Business Media

    Professor Paula I. Moreira

  76. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, October 2016, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  77. Mini-Symposium: Energy Demand and Energy Supply in Alzheimer's Disease - Introduction

    Article • Brain Pathology, September 2016, Wiley

    Professor Paula I. Moreira

  78. Alzheimer's Disease: From Mitochondrial Perturbations to Mitochondrial Medicine

    Article • Brain Pathology, September 2016, Wiley

    Professor Paula I. Moreira

  79. Mitochondria as a target for neuroprotection: implications for Alzheimer´s disease

    Article • Expert Review of Neurotherapeutics, July 2016, Taylor & Francis

    Professor Paula I. Moreira

  80. UMIB Summit 2015

    Article • Medicine, March 2016, Wolters Kluwer Health

    Professor Paula I. Moreira

  81. Erratum

    Article • Autophagy, February 2016, Taylor & Francis

    Dr Janos KristonVizi, Juan Segura-Aguilar, Professor Nektarios Tavernarakis, Dr Reinhard Dechant, Dr Vasilis J Promponas, Professor Marc Lecuit, Professor Paula I. Moreira, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Professor Jean-François Beaulieu, Shile Huang, Maria João Sousa, Professor Godefridus J Peters, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Professor Abdel Halim Harrath, Professor Günther Weindl, Dr Marc Etienne Poirot, Paula Ludovico

  82. Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells

    Article • Molecular Neurobiology, January 2016, Springer Science + Business Media

    Professor Paula I. Moreira

  83. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang, Professor George Perry, Professor Godefridus J Peters, Shuo-Chien Ling, Professor Jiwu Wei, Deepak Shukla, Dave Bridges

  84. Physical exercise mitigates doxorubicin-induced brain cortex and cerebellum mitochondrial alterations and cellular quality control signaling

    Article • Mitochondrion, January 2016, Elsevier

    Professor Paula I. Moreira

  85. Tackling Alzheimer’s Disease by Targeting Oxidative Stress and Mitochondria

    Article • January 2016, Elsevier

    Professor Paula I. Moreira, Professor George Perry

  86. White tea (Camellia sinensis) consumption improves heart and brain glycolytic and oxidative profiles in prediabetic rats

    Article • Planta Medica, November 2015, Thieme Publishing Group

    Professor Branca Maria Silva, Professor Paula I. Moreira

  87. Kaurane diterpenes as mitochondrial alterations preventive agents under experimental oxidative stress conditions

    Article • Pharmaceutical Biology, October 2015, Informa Healthcare

    Professor Paula I. Moreira

  88. Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells

    Article • The International Journal of Biochemistry & Cell Biology, September 2015, Elsevier

    Professor Paula I. Moreira

  89. Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2015, Elsevier

    Professor Paula I. Moreira

  90. Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers

    Article • Neuroscience, August 2015, Elsevier

    Professor Paula I. Moreira

  91. The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases

    Article • Expert Review of Neurotherapeutics, June 2015, Taylor & Francis

    Professor Paula I. Moreira

  92. Metabolic fingerprints in testicular biopsies from type 1 diabetic patients

    Article • Cell and Tissue Research, June 2015, Springer Science + Business Media

    Professor Paula I. Moreira

  93. Abstract book of the 31stESHRE Annual Meeting, Lisbon, Portugal, 14–17 June 2015

    Article • Human Reproduction, June 2015, Oxford University Press (OUP)

    Dr David John McLernon, Professor Paula I. Moreira

  94. Endoplasmic reticulum stress

    Article • CNS & Neurological Disorders - Drug Targets, May 2015, Bentham Science Publishers

    Professor Paula I. Moreira

  95. Alzheimer's Disease-Related Misfolded Proteins and Dysfunctional Organelles on Autophagy Menu

    Article • DNA and Cell Biology, April 2015, Mary Ann Liebert Inc

    Professor Paula I. Moreira

  96. Type 2 Diabetes Aggravates Alzheimer's Disease-Associated Vascular Alterations of the Aorta in Mice

    Article • Journal of Alzheimer’s Disease, March 2015, IOS Press

    Professor Paula I. Moreira

  97. Daily consumption of white tea (Camellia sinensis (L.)) improves the cerebral cortex metabolic and oxidative profile in prediabetic Wistar rats

    Article • British Journal Of Nutrition, February 2015, Cambridge University Press

    Professor Branca Maria Silva, Professor Paula I. Moreira

  98. Exercise-Induced Protection Against Aging and Neurodegenerative Diseases

    Article • February 2015, Wiley

    Professor Paula I. Moreira

  99. Cerebrovascular and mitochondrial abnormalities in Alzheimer’s disease: a brief overview

    Article • Acta Neurovegetativa, January 2015, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  100. Autophagy in Alzheimer’s disease: A Cleaning Service Out-of-order?

    Article • January 2015, Springer Science + Business Media

    Professor Paula I. Moreira

  101. Cardiolipin Profile Changes are Associated to the Early Synaptic Mitochondrial Dysfunction in Alzheimer's Disease

    Article • Journal of Alzheimer’s Disease, December 2014, IOS Press

    Professor Paula I. Moreira

  102. Vascular, Oxidative, and Synaptosomal Abnormalities During Aging and the Progression of Type 2 Diabetes

    Article • Current Neurovascular Research, October 2014, Bentham Science Publishers

    Professor Paula I. Moreira

  103. Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection

    Article • Journal of Bioenergetics and Biomembranes, September 2014, Springer Science + Business Media

    Professor Paula I. Moreira

  104. The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, September 2014, Elsevier

    Professor Paula I. Moreira

  105. Enhanced Amyloidogenic Processing of Amyloid Precursor Protein and Cell Death Under Prolonged Endoplasmic Reticulum Stress in Brain Endothelial Cells

    Article • Molecular Neurobiology, August 2014, Springer Science + Business Media

    Professor Paula I. Moreira

  106. Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease – How Anti-Diabetics Could be a Solution for Dementia

    Article • Frontiers in Endocrinology, July 2014, Frontiers

    Professor Paula I. Moreira

  107. Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, July 2014, Elsevier

    Professor Paula I. Moreira

  108. Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status

    Article • Journal of Bioenergetics and Biomembranes, May 2014, Springer Science + Business Media

    Professor Paula I. Moreira

  109. Amyloid-Beta Disrupts Calcium and Redox Homeostasis in Brain Endothelial Cells

    Article • Molecular Neurobiology, May 2014, Springer Science + Business Media

    Professor Paolo Pinton, Professor Paula I. Moreira

  110. Mitochondrial quality control systems sustain brain mitochondrial bioenergetics in early stages of type 2 diabetes

    Article • Molecular and Cellular Biochemistry, May 2014, Springer Science + Business Media

    Professor Paula I. Moreira

  111. Androgens regulate gene expression of glucose transporters and glycolytic enzymes in prostate cancer cells

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Professor Paula I. Moreira

  112. Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, March 2014, Elsevier

    Professor Paula I. Moreira

  113. Role of Mitochondria and Oxidative Stress in Parkinson’s Disease

    Article • February 2014, Taylor & Francis

    Professor Paula I. Moreira

  114. Metformin and male reproduction: effects on Sertoli cell metabolism

    Article • British Journal of Pharmacology, January 2014, Wiley

    Dr Marco G Alves, Professor Paula I. Moreira

  115. Alzheimer's Disease: An Overview☆

    Article • January 2014, Elsevier

    Professor Paula I. Moreira

  116. Alzheimer's Disease

    Article • January 2014, Elsevier

    Professor Paula I. Moreira

  117. Increased Susceptibility to Amyloid-β Toxicity in Rat Brain Microvascular Endothelial Cells under Hyperglycemic Conditions

    Article • Journal of Alzheimer’s Disease, October 2013, IOS Press

    Professor Paula I. Moreira

  118. The Janus Face of Insulin in Brain

    Article • October 2013, Wiley

    Professor Paula I. Moreira

  119. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease?

    Article • Journal of Neurochemistry, September 2013, Wiley

    Professor George Perry, Professor Paula I. Moreira

  120. Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysis-related transporters and enzymes

    Article • Cell and Tissue Research, September 2013, Springer Science + Business Media

    Professor Paula I. Moreira

  121. Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells

    Article • Reproductive Toxicology, July 2013, Elsevier

    Professor Paula I. Moreira

  122. High-sugar diets, type 2 diabetes and Alzheimerʼs disease

    Article • Current Opinion in Clinical Nutrition & Metabolic Care, July 2013, Wolters Kluwer Health

    Professor Paula I. Moreira

  123. Author Index

    Article • European Journal of Biochemistry, July 2013, Wiley

    Professor Paula I. Moreira

  124. Mitochondrial DNA Oxidative Damage and Repair in Aging and Alzheimer's Disease

    Article • Antioxidants & Redox Signaling, June 2013, Mary Ann Liebert Inc

    Professor George Perry, Professor Paula I. Moreira

  125. Session 01: Keynote lectures session

    Article • Human Reproduction, June 2013, Oxford University Press (OUP)

    Professor Paula I. Moreira

  126. Mitochondrial-Targeted Protective Properties of Isolated Diterpenoids fromSideritisspp. in Response to the Deleterious Changes Induced by H2O2

    Article • Journal of Natural Products, May 2013, American Chemical Society (ACS)

    Professor Paula I. Moreira

  127. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links

    Article • Free Radical Research, May 2013, Taylor & Francis

    Professor George Perry, Professor Paula I. Moreira

  128. Type 2 Diabetic and Alzheimer's Disease Mice Present Similar Behavioral, Cognitive, and Vascular Anomalies

    Article • Journal of Alzheimer’s Disease, May 2013, IOS Press

    Professor Paula I. Moreira

  129. Molecular mechanisms beyond glucose transport in diabetes-related male infertility

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, May 2013, Elsevier

    Professor Paula I. Moreira

  130. Hyperglycemia, Hypoglycemia and Dementia: Role of Mitochondria and Uncoupling Proteins

    Article • Current Molecular Medicine, April 2013, Bentham Science Publishers

    Professor Paula I. Moreira

  131. Mitochondrial Abnormalities in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease

    Article • Current Alzheimer Research, April 2013, Bentham Science Publishers

    Professor Paula I. Moreira, Professor George Perry

  132. Crosstalk between diabetes and brain: Glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, April 2013, Elsevier

    Professor Paula I. Moreira

  133. UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats

    Article • Journal of Bioenergetics and Biomembranes, March 2013, Springer Science + Business Media

    Professor Paula I. Moreira

  134. Phosphorylation of Tau Protein as the Link between Oxidative Stress, Mitochondrial Dysfunction, and Connectivity Failure: Implications for Alzheimer’s Disease

    Article • Oxidative Medicine and Cellular Longevity, January 2013, Hindawi Publishing Corporation

    Professor George Perry, Professor Paula I. Moreira

  135. Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance

    Article • Neurobiology of Disease, January 2013, Elsevier

    Professor Paula I. Moreira

  136. Mechanism of inhibition of mitochondrial ATP synthase by 17β−Estradiol

    Article • Journal of Bioenergetics and Biomembranes, December 2012, Springer Science + Business Media

    Professor Paula I. Moreira

  137. The impairment of insulin signaling in Alzheimer's disease

    Article • IUBMB Life, November 2012, Wiley

    Professor George Perry, Professor Paula I. Moreira

  138. Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile

    Article • The International Journal of Biochemistry & Cell Biology, November 2012, Elsevier

    Cláudio J Maia, Professor Paula I. Moreira

  139. Alzheimer disease as a vascular disorder: Where do mitochondria fit?

    Article • Experimental Gerontology, November 2012, Elsevier

    Professor Paula I. Moreira

  140. Physical exercise as a possible strategy for brain protection: Evidence from mitochondrial-mediated mechanisms

    Article • Progress in Neurobiology, November 2012, Elsevier

    Professor Paula I. Moreira

  141. Impact of Diabetes in Blood-Testis and Blood-Brain Barriers: Resemblances and Differences

    Article • Current Diabetes Reviews, October 2012, Bentham Science Publishers

    Professor Paula I. Moreira

  142. Hormonal control of Sertoli cell metabolism regulates spermatogenesis

    Article • Cellular and Molecular Life Sciences, July 2012, Springer Science + Business Media

    Professor Paula I. Moreira

  143. Alzheimer's Disease and Diabetes: An Integrative View of the Role of Mitochondria, Oxidative Stress, and Insulin

    Article • Journal of Alzheimer’s Disease, June 2012, IOS Press

    Professor Paula I. Moreira

  144. Oxidative Damage to RNA in Aging and Neurodegenerative Disorders

    Article • Neurotoxicity Research, June 2012, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  145. Guidelines for the use and interpretation of assays for monitoring autophagy

    Article • Autophagy, April 2012, Taylor & Francis

    Dave Bridges, Professor CIRO ISIDORO, Professor George Perry, Dr Takeshi Noda, Professor Nektarios Tavernarakis, Matthias Gaestel, Dr Francesca Demarchi, Maria Vaccaro, Juan Segura-Aguilar, Leonardo Travassos, Manoj B Menon, Isabelle Dugail, Dr Legembre Patrick, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Professor Godefridus J Peters, Professor Brigitte Galliot, Professor Luca Scorrano

  146. Association of Mitochondrial Signaling in Alzheimer’s Disease and Hypoxia

    Article • March 2012, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  147. Metabolic Alterations Induced by Sucrose Intake and Alzheimer’s Disease Promote Similar Brain Mitochondrial Abnormalities

    Article • Diabetes, March 2012, American Diabetes Association

    Professor Paula I. Moreira

  148. The role of iron as a mediator of oxidative stress in Alzheimer disease

    Article • BioFactors, March 2012, Wiley

    Professor George Perry, Professor Paula I. Moreira

  149. Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation

    Article • Brain Research, March 2012, Elsevier

    Professor Paula I. Moreira

  150. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover

    Article • Free Radical Biology and Medicine, February 2012, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  151. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

    Article • Free Radical Research, January 2012, Taylor & Francis

    Professor George Perry, Professor Paula I. Moreira

  152. Mitochondrial Importance in Alzheimer’s, Huntington’s and Parkinson’s Diseases

    Article • January 2012, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  153. Glycogen Synthase Kinase 3: A Point of Integration in Alzheimer's Disease and a Therapeutic Target?

    Article • International Journal of Alzheimer s Disease, January 2012, Hindawi Publishing Corporation

    Professor George Perry, Professor Paula I. Moreira

  154. Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1α

    Article • Neurobiology of Disease, January 2012, Elsevier

    Professor Paula I. Moreira

  155. Insulin in Central Nervous System: More than Just a Peripheral Hormone

    Article • Journal of Aging Research, January 2012, Hindawi Publishing Corporation

    Professor Paula I. Moreira

  156. New Insights into the Mechanisms of Mitochondrial Preconditioning-Triggered Neuroprotection

    Article • Current Pharmaceutical Design, October 2011, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  157. Oxidative Stress and Balance in Neurodegenerative Diseases

    Article • September 2011, Wiley

    Professor George Perry, Professor Paula I. Moreira

  158. Neurofilamentopathy in Neurodegenerative Diseases

    Article • The Open Neurology Journal, August 2011, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  159. Mitophagy in Neurodegeneration: An Opportunity for Therapy?

    Article • Current Drug Targets, June 2011, Bentham Science Publishers

    Professor Paula I. Moreira

  160. Effects of rapamycin and TOR on aging and memory: implications for Alzheimer’s disease

    Article • Journal of Neurochemistry, May 2011, Wiley

    Professor Paula I. Moreira

  161. Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?

    Article • Ageing Research Reviews, April 2011, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  162. SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

    Article • Cancer Cell, March 2011, Elsevier

    Professor Paula I. Moreira

  163. Mitochondria as Potential Targets in Antidiabetic Therapy

    Article • January 2011, Springer Science + Business Media

    Professor Paula I. Moreira

  164. Mitochondria from distinct tissues are differently affected by 17β-estradiol and tamoxifen

    Article • The Journal of Steroid Biochemistry and Molecular Biology, January 2011, Elsevier

    Professor Paula I. Moreira

  165. Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, November 2010, Elsevier

    Professor Paula I. Moreira

  166. Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters

    Article • Synapse, October 2010, Wiley

    Professor Paula I. Moreira

  167. Autophagy in Alzheimer’s disease

    Article • Expert Review of Neurotherapeutics, July 2010, Taylor & Francis

    Professor George Perry, Professor Paula I. Moreira

  168. Effects of Estrogen in the Brain: Is it a Neuroprotective Agent in Alzheimers Disease?

    Article • Current Aging Science, July 2010, Bentham Science Publishers

    Professor Paula I. Moreira

  169. A Synergistic Dysfunction of Mitochondrial Fission/Fusion Dynamics and Mitophagy in Alzheimer's Disease

    Article • Journal of Alzheimer’s Disease, June 2010, IOS Press

    Professor George Perry, Professor Paula I. Moreira

  170. Mitochondria: The Missing Link Between Preconditioning and Neuroprotection

    Article • Journal of Alzheimer’s Disease, June 2010, IOS Press

    Professor George Perry, Professor Paula I. Moreira

  171. Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease

    Article • Experimental Neurology, June 2010, Elsevier

    Professor Paula I. Moreira

  172. Mitochondrial preconditioning: a potential neuroprotective strategy

    Article • Frontiers in Aging Neuroscience, January 2010, Frontiers

    Professor George Perry, Professor Paula I. Moreira

  173. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, January 2010, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  174. Mitochondria: A therapeutic target in neurodegeneration

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, January 2010, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  175. Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration?

    Article • Journal of Neurochemistry, January 2010, Wiley

    Professor Paula I. Moreira

  176. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets

    Article • Pharmaceuticals, December 2009, MDPI AG

    Professor George Perry, Professor Paula I. Moreira

  177. Natural Oxidant Balance in Parkinson Disease

    Article • Archives of Neurology, December 2009, American Medical Association (AMA)

    Professor George Perry, Professor Paula I. Moreira

  178. Mitochondria as a Therapeutic Target in Alzheimers Disease and Diabetes

    Article • CNS & Neurological Disorders - Drug Targets, December 2009, Bentham Science Publishers

    Professor Paula I. Moreira

  179. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia

    Article • Journal of Bioenergetics and Biomembranes, October 2009, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  180. Doxorubicin: The Good, the Bad and the Ugly Effect

    Article • Current Medicinal Chemistry, September 2009, Bentham Science Publishers

    Professor Paula I. Moreira

  181. An Integrative View of the Role of Oxidative Stress, Mitochondria and Insulin in Alzheimer's Disease

    Article • Journal of Alzheimer’s Disease, April 2009, IOS Press

    Professor Paula I. Moreira

  182. RNA oxidation in Alzheimer disease and related neurodegenerative disorders

    Article • Acta Neuropathologica, March 2009, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  183. Altered redox balance in disease: Can we change the new equilibria?

    Article • Annals of Neurology, February 2009, Wiley

    Professor George Perry, Professor Paula I. Moreira

  184. Alzheimer’s Disease: An Overview

    Article • January 2009, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  185. Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

    Article • January 2009, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  186. Alzheimer Disease: Oxidative Stress and Compensatory Responses

    Article • January 2009, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  187. Food Deprivation Promotes Oxidative Imbalance in Rat Brain

    Article • Journal of Food Science, January 2009, Wiley

    Professor Paula I. Moreira

  188. Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

    Article • Proceedings of the National Academy of Sciences, December 2008, Proceedings of the National Academy of Sciences

    Professor Paula I. Moreira

  189. Oxidative Stress Signaling in Alzheimers Disease

    Article • Current Alzheimer Research, December 2008, Bentham Science Publishers

    Professor Paula I. Moreira, Professor George Perry

  190. Mechanisms of Action of Metformin in Type 2 Diabetes and Associated Complications: An Overview

    Article • Mini-Reviews in Medicinal Chemistry, November 2008, Bentham Science Publishers

    Professor Paula I. Moreira

  191. Antioxidant Therapy in Alzheimers Disease: Theory and Practice

    Article • Mini-Reviews in Medicinal Chemistry, November 2008, Bentham Science Publishers

    Professor Paula I. Moreira, Professor George Perry

  192. Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage

    Article • Free Radical Biology and Medicine, November 2008, Elsevier

    Professor Paula I. Moreira

  193. Metformin Protects the Brain Against the Oxidative Imbalance Promoted by Type 2 Diabetes

    Article • Medicinal Chemistry, July 2008, Bentham Science Publishers

    Professor Paula I. Moreira

  194. P4‐183: Increased oxidative stress is an early pathological feature in 3xTg‐AD mice

    Article • Alzheimer s & Dementia, July 2008, Wiley

    Professor Paula I. Moreira

  195. Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

    Article • Free Radical Biology and Medicine, June 2008, Elsevier

    Professor Paula I. Moreira

  196. Sublethal RNA Oxidation as a Mechanism for Neurodegenerative Disease

    Article • International Journal of Molecular Sciences, May 2008, MDPI AG

    Professor George Perry, Professor Paula I. Moreira

  197. Nucleic acid oxidation in Alzheimer disease

    Article • Free Radical Biology and Medicine, April 2008, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  198. Alzheimer Disease and the Role of Free Radicals in the Pathogenesis of the Disease

    Article • CNS & Neurological Disorders - Drug Targets, February 2008, Bentham Science Publishers

    Professor Paula I. Moreira, Professor George Perry

  199. Neuronal Death and Survival Under Oxidative Stress in Alzheimer and Parkinson Diseases

    Article • CNS & Neurological Disorders - Drug Targets, December 2007, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  200. Oxidative RNA Damage and Neurodegeneration

    Article • Current Medicinal Chemistry, December 2007, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  201. Metformin promotes isolated rat liver mitochondria impairment

    Article • Molecular and Cellular Biochemistry, October 2007, Springer Science + Business Media

    Professor Paula I. Moreira

  202. Alzheimer's Disease: A Lesson from Mitochondrial Dysfunction

    Article • Antioxidants & Redox Signaling, October 2007, Mary Ann Liebert Inc

    Professor Paula I. Moreira

  203. Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets

    Article • Acta Diabetologica, August 2007, Springer Science + Business Media

    Professor Paula I. Moreira

  204. Errata

    Article • Journal of Neuropathology & Experimental Neurology, July 2007, Oxford University Press (OUP)

    Professor George Perry, Professor Paula I. Moreira

  205. Autophagocytosis of Mitochondria Is Prominent in Alzheimer Disease

    Article • Journal of Neuropathology & Experimental Neurology, June 2007, Oxford University Press (OUP)

    Professor George Perry, Professor Paula I. Moreira

  206. Vascular oxidative stress in Alzheimer disease

    Article • Journal of the Neurological Sciences, June 2007, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  207. Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes

    Article • Journal of the Neurological Sciences, June 2007, Elsevier

    Professor Paula I. Moreira

  208. Iron: The Redox-active Center of Oxidative Stress in Alzheimer Disease

    Article • Neurochemical Research, May 2007, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  209. Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats

    Article • Toxicology and Applied Pharmacology, May 2007, Elsevier

    Professor Paula I. Moreira

  210. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?

    Article • Expert Review of Neurotherapeutics, May 2007, Taylor & Francis

    Professor George Perry, Professor Paula I. Moreira

  211. Indices of Metabolic Dysfunction and Oxidative Stress

    Article • Neurochemical Research, March 2007, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  212. Prevention and Treatment of Alzheimer Disease and Aging: Antioxidants

    Article • Mini-Reviews in Medicinal Chemistry, February 2007, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  213. The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics

    Article • January 2007, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  214. The Key Role of Oxidative Stress in Alzheimer's Disease

    Article • January 2007, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  215. Foreword: Mitochondria in Alzheimer disease

    Article • Journal of Alzheimer’s Disease, July 2006, IOS Press

    Professor Paula I. Moreira

  216. Involvement of Oxidative Stress in Alzheimer Disease

    Article • Journal of Neuropathology & Experimental Neurology, July 2006, Oxford University Press (OUP)

    Professor George Perry, Professor Paula I. Moreira

  217. Telomeres and telomerase in Alzheimer’s disease: Epiphenomena or a new focus for therapeutic strategy?

    Article • Alzheimer s & Dementia, July 2006, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  218. Therapeutic options in Alzheimer’s disease

    Article • Expert Review of Neurotherapeutics, June 2006, Taylor & Francis

    Professor George Perry, Professor Paula I. Moreira

  219. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease

    Article • Mechanisms of Ageing and Development, June 2006, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  220. Neuropathology in Alzheimer's Disease: Awaking from a Hundred-Year-Old Dream

    Article • Science of Aging Knowledge Environment, May 2006, American Association for the Advancement of Science

    Professor George Perry, Professor Paula I. Moreira

  221. Insulin Attenuates Diabetes-Related Mitochondrial Alterations: A Comparative Study

    Article • Medicinal Chemistry, May 2006, Bentham Science Publishers

    Professor Paula I. Moreira

  222. Presenilin mutation: A deadly first hit in Alzheimer disease

    Article • Free Radical Biology and Medicine, March 2006, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  223. Tamoxifen and Estradiol Interact with the Flavin Mononucleotide Site of Complex I Leading to Mitochondrial Failure

    Article • Journal of Biological Chemistry, January 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Paula I. Moreira

  224. Compensatory responses induced by oxidative stress in Alzheimer disease

    Article • Biological Research, January 2006, SciELO Comision Nacional de Investigacion Cientifica Y Tecnologica (CONICYT)

    Professor George Perry, Professor Paula I. Moreira

  225. CoQ10 therapy attenuates amyloid β-peptide toxicity in brain mitochondria isolated from aged diabetic rats

    Article • Experimental Neurology, November 2005, Elsevier

    Professor Paula I. Moreira

  226. Oxidative Stress: The Old Enemy in Alzheimers Disease Pathophysiology

    Article • Current Alzheimer Research, October 2005, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  227. Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease

    Article • Letters in Drug Design & Discovery, September 2005, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  228. Alzheimer's disease: an intracellular movement disorder?

    Article • Trends in Molecular Medicine, September 2005, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  229. Redox metals and oxidative abnormalities in human prion diseases

    Article • Acta Neuropathologica, August 2005, Springer Science + Business Media

    Professor George Perry, Prof. Herbert Budka, Professor Paula I. Moreira, Mark Smith

  230. Alzheimers Disease-Associated Neurotoxic Mechanisms and Neuroprotective Strategies

    Article • Current Drug Targets - CNS & Neurological Disorders, August 2005, Bentham Science Publishers

    Professor Paula I. Moreira

  231. Neurodegenerative Pathways in Parkinsons Disease: Therapeutic Strategies

    Article • Current Drug Targets - CNS & Neurological Disorders, August 2005, Bentham Science Publishers

    Professor Paula I. Moreira

  232. Oxidative Stress and Neurodegeneration

    Article • Annals of the New York Academy of Sciences, June 2005, Wiley

    Professor George Perry, Professor Paula I. Moreira

  233. Therapeutic Opportunities in Alzheimer Disease: One for all or all for One?

    Article • Current Medicinal Chemistry, May 2005, Bentham Science Publishers

    Professor George Perry, Professor Paula I. Moreira

  234. Chronological primacy of oxidative stress in Alzheimer disease

    Article • Neurobiology of Aging, May 2005, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  235. Tau phosphorylation in Alzheimer's disease: pathogen or protector?

    Article • Trends in Molecular Medicine, April 2005, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  236. A Second Look into the Oxidant Mechanisms in Alzheimers Disease

    Article • Current Neurovascular Research, April 2005, Bentham Science Publishers

    Professor Paula I. Moreira

  237. Insulin protects against amyloid β-peptide toxicity in brain mitochondria of diabetic rats

    Article • Neurobiology of Disease, April 2005, Elsevier

    Professor Paula I. Moreira

  238. Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

    Article • Journal of Biological Chemistry, March 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor George Perry, Professor Paula I. Moreira

  239. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

    Article • Free Radical Biology and Medicine, March 2005, Elsevier

    Professor George Perry, Professor Paula I. Moreira

  240. Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen

    Article • Neuropharmacology, March 2005, Elsevier

    Professor Paula I. Moreira

  241. Mitogen- and stress-activated protein kinase 1: Convergence of the ERK and p38 pathways in Alzheimer's disease

    Article • Journal of Neuroscience Research, January 2005, Wiley

    Professor George Perry, Professor Paula I. Moreira

  242. Biphasic expression of lipin suggests dual roles in adipocyte development

    Article • Drug News & Perspectives, January 2005, Thomson Reuters (Scientific) Inc. & Affiliates

    Professor Paula I. Moreira

  243. Oxidative stress mechanisms and potential therapeutics in Alzheimer disease

    Article • Acta Neurovegetativa, December 2004, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  244. Neurofilament proteins in neurodegenerative diseases

    Article • Cellular and Molecular Life Sciences, December 2004, Springer Science + Business Media

    Professor George Perry, Professor Paula I. Moreira

  245. Therapeutic potential of oxidant mechanisms in Alzheimer’s disease

    Article • Expert Review of Neurotherapeutics, November 2004, Taylor & Francis

    Professor George Perry, Professor Paula I. Moreira

  246. Hydroxytamoxifen protects against oxidative stress in brain mitochondria

    Article • Biochemical Pharmacology, July 2004, Elsevier

    Professor Paula I. Moreira

  247. Effect of Streptozotocin-Induced Diabetes on Rat Brain Mitochondria

    Article • Journal of Neuroendocrinology, January 2004, Wiley

    Professor Paula I. Moreira

  248. Effect of Streptozotocin‐Induced Diabetes on Rat Brain Mitochondria

    Article • Journal of Neuroendocrinology, January 2004, Wiley

    Professor Paula I. Moreira

  249. Increased Vulnerability of Brain Mitochondria in Diabetic (Goto-Kakizaki) Rats With Aging and Amyloid-  Exposure

    Article • Diabetes, June 2003, American Diabetes Association

    Professor Paula I. Moreira

  250. Effect of amyloid ?-peptide on permeability transition pore: A comparative study

    Article • Journal of Neuroscience Research, June 2002, Wiley

    Professor Paula I. Moreira

  251. Amyloid β-Peptide Promotes Permeability Transition Pore in Brain Mitochondria

    Article • Bioscience Reports, December 2001, Portland Press Ltd.

    Professor Paula I. Moreira

  252. Effect of Zinc Ions on the Cytotoxicity Induced by the Amyloid β-Peptide

    Article • Antioxidants & Redox Signaling, June 2000, Mary Ann Liebert Inc

    Professor Paula I. Moreira

  253. Susceptibility to β-Amyloid-Induced Toxicity Is Decreased in Goto-Kakizaki Diabetic Rats: Involvement of Oxidative Stress

    Article • Experimental Neurology, January 2000, Elsevier

    Professor Paula I. Moreira