All Stories

  1. Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy

    Article • Diabetes, November 2020, American Diabetes Association

    Isabelle Dugail

  2. Phosphatidylglycerols are novel lipids dysregulated in obesity

    Article • The FASEB Journal, April 2019, Federation of American Societies For Experimental Biology (FASEB)

    Isabelle Dugail, Anatol Kontush, Dr Luis G BERMUDEZ-HUMARAN

  3. Normal human adipose tissue functions and differentiation in patients with biallelicLPIN1inactivating mutations

    Article • Journal of Lipid Research, October 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Isabelle Dugail

  4. Specific roles of phosphatidylglycerols in hosts and microbes

    Article • Biochimie, October 2017, Elsevier

    Isabelle Dugail

  5. Serum lipidomics reveals early differential effects of gastric bypass compared with banding on phospholipids and sphingolipids independent of differences in weight loss

    Article • International Journal of Obesity, March 2017, Springer Science + Business Media

    Isabelle Dugail

  6. Atrial natriuretic peptide regulates adipose tissue accumulation in adult atria

    Article • Proceedings of the National Academy of Sciences, January 2017, Proceedings of the National Academy of Sciences

    Isabelle Dugail

  7. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang

  8. Adipose tissue autophagy status in obesity: Expression and flux—two faces of the picture

    Article • Autophagy, November 2015, Taylor & Francis

    Isabelle Dugail

  9. DAPK2 Downregulation Associates With Attenuated Adipocyte Autophagic Clearance in Human Obesity

    Article • Diabetes, June 2015, American Diabetes Association

    Isabelle Dugail, Maria Pini

  10. Circulating phospholipid profiling identifies portal contribution to NASH signature in obesity

    Article • Journal of Hepatology, April 2015, Elsevier

    Isabelle Dugail

  11. Hypoxia Inhibits Cavin-1 and Cavin-2 Expression and Down-Regulates Caveolae in Adipocytes

    Article • Endocrinology, March 2015, Endocrine Society

    Isabelle Dugail

  12. Adipocyte size fluctuation, mechano-active lipid droplets and caveolae

    Article • Adipocyte, December 2014, Taylor & Francis

    Isabelle Dugail

  13. Adipocyte ATP-Binding Cassette G1 Promotes Triglyceride Storage, Fat Mass Growth, and Human Obesity

    Article • Diabetes, September 2014, American Diabetes Association

    Isabelle Dugail

  14. Caveolin-1 Expression and Cavin Stability Regulate Caveolae Dynamics in Adipocyte Lipid Store Fluctuation

    Article • Diabetes, June 2014, American Diabetes Association

    Isabelle Dugail

  15. Lipids in metabolic diseases

    Article • Biochimie, January 2014, Elsevier

    Isabelle Dugail

  16. Lysosome/lipid droplet interplay in metabolic diseases

    Article • Biochimie, January 2014, Elsevier

    Isabelle Dugail

  17. The dynamics of accumulation of PCBs in cultured adipocytes vary with the cell lipid content and the lipophilicity of the congener

    Article • Toxicology Letters, January 2013, Elsevier

    Isabelle Dugail

  18. Effect of IVIg on human dendritic cell-mediated antigen uptake and presentation: Role of lipid accumulation

    Article • Journal of Autoimmunity, September 2012, Elsevier

    Isabelle Dugail

  19. Guidelines for the use and interpretation of assays for monitoring autophagy

    Article • Autophagy, April 2012, Taylor & Francis

    Dave Bridges, Professor CIRO ISIDORO, Professor George Perry, Dr Takeshi Noda, Professor Nektarios Tavernarakis, Matthias Gaestel, Dr Francesca Demarchi, Maria Vaccaro, Juan Segura-Aguilar, Leonardo Travassos, Manoj B Menon, Isabelle Dugail, Dr Legembre Patrick, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke

  20. Accumulation of Polychlorinated Biphenyls in Adipocytes: Selective Targeting to Lipid Droplets and Role of Caveolin-1

    Article • PLoS ONE, February 2012, PLOS

    Isabelle Dugail

  21. Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes

    Article • Journal of Hepatology, July 2011, Elsevier

    Isabelle Dugail

  22. Distinct Roles of Endothelial and Adipocyte Caveolin-1 in Macrophage Infiltration and Adipose Tissue Metabolic Activity

    Article • Diabetes, January 2011, American Diabetes Association

    Isabelle Dugail

  23. Cavin proteins: New players in the caveolae field

    Article • Biochimie, January 2011, Elsevier

    Isabelle Dugail

  24. The lipoatrophic caveolin-1 deficient mouse model reveals autophagy in mature adipocytes

    Article • Autophagy, August 2010, Taylor & Francis

    Isabelle Dugail

  25. Little caves ameliorate hepatic insulin signaling. Focus on “Caveolin gene transfer improves glucose metabolism in diabetic mice”

    Article • AJP Cell Physiology, March 2010, American Physiological Society

    Isabelle Dugail

  26. Plasma Membrane Subdomain Compartmentalization Contributes to Distinct Mechanisms of Ceramide Action on Insulin Signaling

    Article • Diabetes, December 2009, American Diabetes Association

    Isabelle Dugail

  27. Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects

    Article • Journal of Lipid Research, November 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Isabelle Dugail

  28. Filling up adipocytes with lipids. Lessons from caveolin-1 deficiency

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, June 2009, Elsevier

    Isabelle Dugail

  29. Connecting lipid droplet biology and the metabolic syndrome

    Article • Progress in Lipid Research, May 2009, Elsevier

    Isabelle Dugail

  30. Antidepressant Phenelzine Alters Differentiation of Cultured Human and Mouse Preadipocytes

    Article • Molecular Pharmacology, February 2009, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Isabelle Dugail

  31. Regulated association of caveolins to lipid droplets during differentiation of 3T3-L1 adipocytes

    Article • Biochemical and Biophysical Research Communications, November 2008, Elsevier

    Isabelle Dugail

  32. Association of a Homozygous Nonsense Caveolin-1 Mutation with Berardinelli-Seip Congenital Lipodystrophy

    Article • The Journal of Clinical Endocrinology & Metabolism, April 2008, Endocrine Society

    Isabelle Dugail

  33. La vitamine A, loin des yeux… près du gras

    Article • médecine/sciences, November 2007, EDP Sciences

    Isabelle Dugail

  34. Lipid sensing and lipid sensors

    Article • Cellular and Molecular Life Sciences, September 2007, Springer Science + Business Media

    Isabelle Dugail

  35. De novo cholesterol synthesis at the crossroads of adaptive response to extracellular stress through SREBP

    Article • Biochimie, February 2007, Elsevier

    Isabelle Dugail

  36. Cholesterol-Induced Caveolin Targeting to Lipid Droplets in Adipocytes: A Role for Caveolar Endocytosis

    Article • Traffic, March 2006, Wiley

    Isabelle Dugail

  37. Caspase-2, a Novel Lipid Sensor under the Control of Sterol Regulatory Element Binding Protein 2

    Article • Molecular and Cellular Biology, November 2005, ASM Journals

    Isabelle Dugail

  38. Insulin and Angiotensin II Induce the Translocation of Scavenger Receptor Class B, Type I from Intracellular Sites to the Plasma Membrane of Adipocytes

    Article • Journal of Biological Chemistry, July 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Isabelle Dugail

  39. Le tissu adipeux : nouveaux aspects

    Article • Annales Pharmaceutiques Françaises, March 2004, Elsevier

    Isabelle Dugail

  40. Adipocyte cholesterol balance in obesity

    Article • Biochemical Society Transactions, February 2004, Portland Press Ltd.

    Isabelle Dugail

  41. In VitroSuppression of the Lipogenic Pathway by the Nonnucleoside Reverse Transcriptase Inhibitor Efavirenz in 3T3 and Human Preadipocytes or Adipocytes

    Article • Journal of Biological Chemistry, January 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Isabelle Dugail

  42. Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells

    Article • Journal of Lipid Research, May 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Isabelle Dugail

  43. New Insights into How Adipocytes Sense their Triglyceride Stores. Is Cholesterol a Signal?

    Article • Hormone and Metabolic Research, April 2003, Thieme Publishing Group

    Isabelle Dugail

  44. Human alpha 2A-adrenergic receptor gene expressed in transgenic mouse adipose tissue under the control of its regulatory elements

    Article • Journal of Molecular Endocrinology, October 2002, Bioscientifica

    Isabelle Dugail

  45. Angiotensin II-responsive element is the insulin-responsive element in the adipocyte fatty acid synthase gene: role of adipocyte determination and differentiation factor 1/sterol-regulatory-element-binding protein 1c

    Article • Biochemical Journal, August 2001, Portland Press Ltd.

    Isabelle Dugail

  46. Cholesterol, a Cell Size-dependent Signal That Regulates Glucose Metabolism and Gene Expression in Adipocytes

    Article • Journal of Biological Chemistry, February 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Isabelle Dugail

  47. Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adipoc...

    Article • Biochemical Journal, December 1999, Portland Press Ltd.

    Isabelle Dugail

  48. ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose

    Article • Molecular and Cellular Biology, May 1999, ASM Journals

    Isabelle Dugail

  49. Leptin Receptor Gene in a Large Cohort of Massively Obese Subjects: No Indication of the fa/fa Rat Mutation. Detection of an Intronic Variant with No Association with Obesity

    Article • Obesity Research, March 1998, Wiley

    Isabelle Dugail

  50. Pioglitazone Induces In Vivo Adipocyte Differentiation in the Obese Zucker fa/fa Rat

    Article • Diabetes, September 1997, American Diabetes Association

    Isabelle Dugail

  51. A GC-rich Region Containing Sp1 and Sp1-like Binding Sites Is a Crucial Regulatory Motif for Fatty Acid Synthase Gene Promoter Activity in Adipocytes

    Article • Journal of Biological Chemistry, August 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Isabelle Dugail

  52. C/EBPα Expression in Adipose Tissue of Genetically Obese Zucker Rats

    Article • Biochemical and Biophysical Research Communications, February 1995, Elsevier

    Isabelle Dugail

  53. Evidence of Increased Glyceraldehyde-3-phosphate Dehydrogenase and Fatty Acid Synthetase Promoter Activities in Transiently Transfected Adipocytes from Genetically Obese Rats

    Article • Journal of Biological Chemistry, January 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Isabelle Dugail

  54. Sequence of rat lipoprotein lipase-encoding cDNA

    Article • Gene, November 1992, Elsevier

    Isabelle Dugail

  55. Differential polypeptide expression in adipose tissue of lean and obese Zucker rats. Evidence of specifically repressed peptides in 7-day-old pre-obese rats

    Article • Biochemical Journal, June 1992, Portland Press Ltd.

    Isabelle Dugail

  56. Gene expression of lipid storage-related enzymes in adipose tissue of the genetically obese Zucker rat. Co-ordinated increase in transcriptional activity and potentiation by hyperinsulinaemia

    Article • Biochemical Journal, February 1992, Portland Press Ltd.

    Isabelle Dugail

  57. Adipsin mRNA amounts are not decreased in the genetically obese Zucker rat

    Article • Biochemical Journal, February 1989, Portland Press Ltd.

    Isabelle Dugail

  58. Adipose-tissue-specific increase in glyceraldehyde-3-phosphate dehydrogenase activity and mRNA amounts in suckling pre-obese Zucker rats. Effect of weaning

    Article • Biochemical Journal, September 1988, Portland Press Ltd.

    Isabelle Dugail

  59. Differential effects of retinoic acid upon early and late events in adipose conversion of 3T3 preadipocytes

    Article • Experimental Cell Research, July 1988, Elsevier

    Isabelle Dugail

  60. Increased lipoprotein lipase content in the adipose tissue of suckling and weaning obese Zucker rats

    Article • Biochemical Journal, January 1988, Portland Press Ltd.

    Isabelle Dugail

  61. A method for separating cultured preadipocytes according to their density: Application to stromal cells from overfed suckling rats

    Article • In Vitro Cellular & Developmental Biology - Plant, July 1986, Springer Science + Business Media

    Isabelle Dugail