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  1. Vitamin E components give a multitude of oxidation products.

    Article • Food Bioscience, October 2022, Elsevier

    Dr Marc Etienne Poirot

  2. Celebrating the 10th anniversary of the creation of the European Network for Oxysterol Research (ENOR)

    Article • The Journal of Steroid Biochemistry and Molecular Biology, July 2022, Elsevier

    Dr Marc Etienne Poirot

  3. Cholesterol is a lipid producing signaling molecules controlling Aging

    Article • Ageing Research Reviews, May 2022, Elsevier

    Dr Marc Etienne Poirot

  4. Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles

    Article • Journal of Extracellular Vesicles, April 2022, Wiley

    Dr Marc Etienne Poirot

  5. Pharmacologic and genetic inhibition of cholesterol esterification enzymes reduces tumour burden: A systematic review and meta-analysis of preclinical models

    Article • Biochemical Pharmacology, February 2022, Elsevier

    Dr Marc Etienne Poirot

  6. Sterol metabolism and cancer

    Article • Biochemical Pharmacology, February 2022, Elsevier

    Dr Marc Etienne Poirot

  7. European network for oxysterol research (ENOR): 10 th anniversary

    Article • The Journal of Steroid Biochemistry and Molecular Biology, November 2021, Elsevier

    Dr Marc Etienne Poirot

  8. Pharmacologic and genetic inhibition of cholesterol esterification reduces tumour burden: a pan-cancer systematic review and meta-analysis of preclinical models

    Article • June 2021, Cold Spring Harbor Laboratory Press

    Dr Marc Etienne Poirot

  9. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Article • Autophagy, January 2021, Taylor & Francis

    MD, PhD Pierre-Louis Tharaux, Joilson O. Martins, Dr. rer. nat. Marc Herb, Dr Marcia R Cominetti, Alessio Di Fonzo, Christoph Gerhardt, Dr Mustafa Sahin, Dr Cinzia Volonté, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Prof Robert Bryson-Richardson, Professor Hyun Kyu Song, Prof Claudia Cavadas, Professor Po Sing Leung, Paula Ludovico, Javeed Shah, Giovanni Di Guardo, Dr Takeshi Noda, Professor Tullio Florio, Professor Kevin Coombs, Ning Chen

  10. Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia

    Article • Cancers, October 2020, MDPI AG

    Dr Marc Etienne Poirot

  11. The 5,6‐epoxycholesterol metabolic pathway in breast cancer: Emergence of new pharmacological targets

    Article • British Journal of Pharmacology, August 2020, Wiley

    Dr Marc Etienne Poirot

  12. Dendrogenin A Synergizes with Cytarabine to Kill Acute Myeloid Leukemia Cells In Vitro and In Vivo

    Article • Cancers, June 2020, MDPI AG

    Dr Marc Etienne Poirot

  13. The 5,6-epoxycholesterol metabolic pathway in cancer: emergence of new pharmacological targets

    Article • May 2020, Authorea, Inc.

    Dr Marc Etienne Poirot

  14. Oxysterols and sterols: From lipidomics to food sciences

    Article • The Journal of Steroid Biochemistry and Molecular Biology, February 2020, Elsevier

    Dr Marc Etienne Poirot

  15. A fast UPLC–HILIC method for an accurate quantification of dendrogenin A in human tissues

    Article • The Journal of Steroid Biochemistry and Molecular Biology, November 2019, Elsevier

    Dr Marc Etienne Poirot

  16. Oxysterols: An expanding family of structurally diversified bioactive steroids

    Article • The Journal of Steroid Biochemistry and Molecular Biology, November 2019, Elsevier

    Dr Marc Etienne Poirot

  17. The cholesterol-derived metabolite dendrogenin A functionally reprograms breast adenocarcinoma and undifferentiated thyroid cancer cells

    Article • The Journal of Steroid Biochemistry and Molecular Biology, September 2019, Elsevier

    Dr Marc Etienne Poirot

  18. Flavonoids differentially modulate liver X receptors activity—Structure-function relationship analysis

    Article • The Journal of Steroid Biochemistry and Molecular Biology, June 2019, Elsevier

    Dr Marc Etienne Poirot

  19. Natural and semisynthetic oxyprenylated aromatic compounds as stimulators or inhibitors of melanogenesis

    Article • Bioorganic Chemistry, June 2019, Elsevier

    Dr Marc Etienne Poirot

  20. HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of Anethum Graveolens, Pimpinella Anisum, and Ferulago Campestris

    Article • Molecules, January 2019, MDPI AG

    Dr Marc Etienne Poirot

  21. Chemistry, biochemistry, metabolic fate and mechanism of action of 6-oxo-cholestan-3β,5α-diol (OCDO), a tumor promoter and cholesterol metabolite

    Article • Biochimie, October 2018, Elsevier

    Dr Marc Etienne Poirot

  22. The Effects of Cholesterol-Derived Oncometabolites on Nuclear Receptor Function in Cancer

    Article • Cancer Research, August 2018, American Association for Cancer Research (AACR)

    Dr Marc Etienne Poirot

  23. Extracellular vesicles: lipids as key components of their biogenesis and functions

    Article • Journal of Lipid Research, August 2018, Elsevier

    Dr Marc Etienne Poirot

  24. The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers

    Article • Biochemical Pharmacology, July 2018, Elsevier

    Dr Marc Etienne Poirot

  25. Ligand-dependent transcriptional induction of lethal autophagy: A new perspective for cancer treatment

    Article • Autophagy, March 2018, Taylor & Francis

    Dr Marc Etienne Poirot

  26. Bryonolic Acid Blocks Cancer Cell Clonogenicity and Invasiveness through the Inhibition of Fatty Acid: Cholesteryl Ester Formation

    Article • Biomedicines, February 2018, MDPI AG

    Dr Marc Etienne Poirot

  27. Meet Our Editorial Board Member

    Article • The Natural Products Journal, February 2018, Bentham Science Publishers

    Dr Marc Etienne Poirot

  28. Dendrogenin A (DDA) is a cholesterol metabolite with potent anticancer properties

    Article • Nature Communications, December 2017, Nature

    Dr Marie Tosolini, Dr Marc Etienne Poirot

  29. Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death

    Article • Biochemical Pharmacology, November 2017, Elsevier

    Dr Marc Etienne Poirot

  30. Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

    Article • Proceedings of the National Academy of Sciences, October 2017, Proceedings of the National Academy of Sciences

    Dr Marc Etienne Poirot

  31. Quantitative analysis of the tumor suppressor dendrogenin A using liquid chromatography tandem mass spectrometry

    Article • Chemistry and Physics of Lipids, October 2017, Elsevier

    Dr Marc Etienne Poirot

  32. Improvement of 5,6α-epoxycholesterol, 5,6β-epoxycholesterol, cholestane-3β,5α,6β-triol and 6-oxo-cholestan-3β,5α-diol recovery for quantification by GC/MS

    Article • Chemistry and Physics of Lipids, October 2017, Elsevier

    Dr Marc Etienne Poirot

  33. Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study

    Article • The Journal of Steroid Biochemistry and Molecular Biology, May 2017, Elsevier

    Dr Marc Etienne Poirot

  34. From tamoxifen to dendrogenin A: The discovery of a mammalian tumor suppressor and cholesterol metabolite

    Article • Biochimie, November 2016, Elsevier

    Dr Marc Etienne Poirot

  35. When cholesterol meets histamine, it gives rise to dendrogenin A: a tumour suppressor metabolite1

    Article • Biochemical Society Transactions, April 2016, Portland Press Ltd.

    Dr Marc Etienne Poirot

  36. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang

  37. dendrogenin A: a good cholesterol metabolite against cancer

    Article • Current Medicinal Chemistry, October 2015, Bentham Science Publishers

    Dr Marc Etienne Poirot

  38. Cholesterol metabolites exported from human brain

    Article • Steroids, July 2015, Elsevier

    Dr Marc Etienne Poirot

  39. One step synthesis of 6-oxo-cholestan-3β,5α-diol

    Article • Biochemical and Biophysical Research Communications, April 2014, Elsevier

    Dr Marc Etienne Poirot

  40. The novel steroidal alkaloids dendrogenin A and B promote proliferation of adult neural stem cells

    Article • Biochemical and Biophysical Research Communications, April 2014, Elsevier

    Dr Marc Etienne Poirot

  41. Cholesterol and Cancer, in the Balance

    Article • Science, March 2014, American Association for the Advancement of Science

    Dr Marc Etienne Poirot

  42. Emerging concepts on the role of exosomes in lipid metabolic diseases

    Article • Biochimie, January 2014, Elsevier

    Dr Marc Etienne Poirot

  43. Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, January 2014, Elsevier

    Dr Marc Etienne Poirot

  44. Progesterone and a phospholipase inhibitor increase the endosomal bis(monoacylglycero)phosphate content and block HIV viral particle intercellular transmission

    Article • Biochimie, September 2013, Elsevier

    Dr Marc Etienne Poirot

  45. 5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of Tamoxifen in breast cancer cells

    Article • Biochemical Pharmacology, July 2013, Elsevier

    Dr Marc Etienne Poirot

  46. Oxysterols and related sterols: Implications in pharmacology and pathophysiology

    Article • Biochemical Pharmacology, July 2013, Elsevier

    Dr Marc Etienne Poirot

  47. Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties

    Article • Nature Communications, May 2013, Nature

    Dr Thomas Filleron, Dr Marc Etienne Poirot

  48. Improved realism of hybrid mouse models may not be sufficient to generate reference dosimetric data

    Article • Medical Physics, April 2013, Wiley

    Dr Marc Etienne Poirot

  49. Cholesterol-5,6-epoxides: Chemistry, biochemistry, metabolic fate and cancer

    Article • Biochimie, March 2013, Elsevier

    Dr Marc Etienne Poirot

  50. Technical note: Hapten synthesis, antibody production and development of an enzyme-linked immunosorbent assay for detection of the natural steroidal alkaloid Dendrogenin A

    Article • Biochimie, March 2013, Elsevier

    Dr Marc Etienne Poirot

  51. Cholesterol epoxide hydrolase and cancer

    Article • Current Opinion in Pharmacology, December 2012, Elsevier

    Dr Marc Etienne Poirot

  52. Cholesterol metabolism and cancer: the good, the bad and the ugly

    Article • Current Opinion in Pharmacology, December 2012, Elsevier

    Dr Marc Etienne Poirot

  53. Cholesterol metabolism and resistance to tamoxifen

    Article • Current Opinion in Pharmacology, December 2012, Elsevier

    Dr Marc Etienne Poirot

  54. MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy

    Article • Autophagy, July 2012, Taylor & Francis

    Dr Marc Etienne Poirot

  55. Guidelines for the use and interpretation of assays for monitoring autophagy

    Article • Autophagy, April 2012, Taylor & Francis

    Dave Bridges, Professor CIRO ISIDORO, Professor George Perry, Dr Takeshi Noda, Professor Nektarios Tavernarakis, Matthias Gaestel, Dr Francesca Demarchi, Maria Vaccaro, Juan Segura-Aguilar, Leonardo Travassos, Manoj B Menon, Isabelle Dugail, Dr Legembre Patrick, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke

  56. Identification of a new stilbene-derived inducer of paraoxonase 1 and ligand of the Aryl hydrocarbon Receptor

    Article • Biochemical Pharmacology, March 2012, Elsevier

    Dr Marc Etienne Poirot

  57. Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles

    Article • Journal of Lipid Research, January 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Marc Etienne Poirot

  58. Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands

    Article • Chemistry and Physics of Lipids, September 2011, Elsevier

    Dr Marc Etienne Poirot

  59. Exosomes as intercellular signalosomes and pharmacological effectors

    Article • Biochemical Pharmacology, May 2011, Elsevier

    Dr Marc Etienne Poirot

  60. Four decades of discovery in breast cancer research and treatment an interview with V. Craig Jordan

    Article • The International Journal of Developmental Biology, January 2011, UBC Press

    Dr Marc Etienne Poirot

  61. Auraptene Is an Inhibitor of Cholesterol Esterification and a Modulator of Estrogen Receptors

    Article • Molecular Pharmacology, August 2010, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Marc Etienne Poirot

  62. Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands

    Article • Proceedings of the National Academy of Sciences, July 2010, Proceedings of the National Academy of Sciences

    Dr Marc Etienne Poirot

  63. Development of a new radioligand for cholecystokinin receptor subtype 2 scintigraphy: From molecular modeling to in vivo evaluation

    Article • Bioorganic & Medicinal Chemistry, July 2010, Elsevier

    Dr Marc Etienne Poirot

  64. Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

    Article • Journal of Lipid Research, April 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Marc Etienne Poirot

  65. Synthesis, characterization and in vitro evaluation of new oxorhenium- and oxotechnetium-CCK4 derivatives as molecular imaging agents for CCK2-receptor targeting

    Article • European Journal of Medicinal Chemistry, February 2010, Elsevier

    Dr Marc Etienne Poirot

  66. Synthesis of New Alkylaminooxysterols with Potent Cell Differentiating Activities: Identification of Leads for the Treatment of Cancer and Neurodegenerative Diseases

    Article • Journal of Medicinal Chemistry, December 2009, American Chemical Society (ACS)

    Dr Marc Etienne Poirot

  67. Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism

    Article • Cell Death and Differentiation, June 2009, Springer Science + Business Media

    Dr Marc Etienne Poirot

  68. Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion

    Article • Journal of Lipid Research, June 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Marc Etienne Poirot

  69. Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism

    Article • Molecular Cancer Therapeutics, December 2008, American Association for Cancer Research (AACR)

    Dr Marc Etienne Poirot

  70. Insights into the Cholecystokinin 2 Receptor Binding Site and Processes of Activation

    Article • Molecular Pharmacology, September 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Marc Etienne Poirot

  71. The Prototypical Inhibitor of Cholesterol Esterification, Sah 58-035 [3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenylethyl]propanamide], Is an Agonist of Estrogen Receptors

    Article • Journal of Pharmacology and Experimental Therapeutics, July 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Marc Etienne Poirot

  72. Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways

    Article • November 2005, Springer Science + Business Media

    Dr Marc Etienne Poirot

  73. Synthesis and Biological Properties of New Stilbene Derivatives of Resveratrol as New Selective Aryl Hydrocarbon Modulators

    Article • Journal of Medicinal Chemistry, January 2005, American Chemical Society (ACS)

    Dr Marc Etienne Poirot

  74. Molecular Characterization of the Microsomal Tamoxifen Binding Site

    Article • Journal of Biological Chemistry, June 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Marc Etienne Poirot

  75. Tamoxifen Is a Potent Inhibitor of Cholesterol Esterification and Prevents the Formation of Foam Cells

    Article • Journal of Pharmacology and Experimental Therapeutics, November 2003, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Marc Etienne Poirot

  76. High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor

    Article • Oncogene, September 2003, Springer Science + Business Media

    Dr Marc Etienne Poirot

  77. Identification of Tyrosine 189 and Asparagine 358 of the Cholecystokinin 2 Receptor in Direct Interaction with the Crucial C-Terminal Amide of Cholecystokinin by Molecular Modeling, Site-Directed Mutagenesis, and Structure/Affinity Studies

    Article • Molecular Pharmacology, May 2003, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Marc Etienne Poirot

  78. Contrasting Effects of Prenyltransferase Inhibitors on Estrogen-Dependent Cell Cycle Progression and Estrogen Receptor-Mediated Transcriptional Activity in MCF-7 Cells

    Article • Endocrinology, March 2003, Endocrine Society

    Professor Gilles Favre, Dr Marc Etienne Poirot

  79. Insulin and estrogen receptor ligand influence the FGF-2 activities in MCF-7 breast cancer cells

    Article • Biochemical Pharmacology, February 2003, Elsevier

    Dr Marc Etienne Poirot

  80. Identification of Two Tamoxifen Target Proteins by Photolabeling with 4-(2-Morpholinoethoxy)benzophenone

    Article • Bioconjugate Chemistry, July 2002, American Chemical Society (ACS)

    Dr Marc Etienne Poirot

  81. Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor

    Article • Biochemical Pharmacology, December 1999, Elsevier

    Dr Marc Etienne Poirot

  82. Different populations of progesterone receptor–steroid complexes in binding to specific DNA sequences: effects of salts on kinetics and specificity

    Article • The Journal of Steroid Biochemistry and Molecular Biology, November 1998, Elsevier

    Dr Marc Etienne Poirot

  83. Characterization of the Membranous Antiestrogen Binding Protein: I Partial purification of the protein in its active state

    Article • Journal of Receptor Research, January 1994, Taylor & Francis

    Dr Marc Etienne Poirot

  84. Characterization of the Membranous Antiestrogen Binding Protein: II Purification to homogeneity

    Article • Journal of Receptor Research, January 1994, Taylor & Francis

    Dr Marc Etienne Poirot

  85. Characterization of a benzyl-phenoxy-ethanamine binding protein in Trypanosoma equiperdum and the possible relation between binding affinity and trypanocidal activity

    Article • Molecular and Biochemical Parasitology, April 1993, Elsevier

    Dr Marc Etienne Poirot

  86. Cytosolic Type II Estrogen Binding Site in Rat Uterus: Specific Photolabeling with Estrone

    Article • Journal of Receptor Research, January 1992, Taylor & Francis

    Dr Marc Etienne Poirot

  87. The anti-proliferative properties of 4-benzylphenoxy ethanamine derivatives are mediated by the anti-estrogen binding site (ABS), whereas the anti-estrogenic effects of trifluopromazine are not

    Article • Biochemical Pharmacology, August 1990, Elsevier

    Dr Marc Etienne Poirot

  88. Further evidence for a biological role of anti-estrogen-binding sites in mediating the growth inhibitory action of diphenylmethane derivatives

    Article • Chemico-Biological Interactions, January 1988, Elsevier

    Dr Marc Etienne Poirot