All Stories

  1. Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages

    Article • Cell Reports, May 2025, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  2. The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization

    Article • Cell Reports, September 2024, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  3. Travelling under pressure - hypoxia and shear stress in the metastatic journey

    Article • Clinical & Experimental Metastasis, July 2023, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  4. The peroxisome: an up-and-coming organelle in immunometabolism

    Article • Trends in Cell Biology, January 2023, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  5. Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis

    Article • Frontiers in Cell and Developmental Biology, November 2020, Frontiers

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  6. A Functional SMAD2/3 Binding Site in the PEX11β Promoter Identifies a Role for TGFβ in Peroxisome Proliferation in Humans

    Article • Frontiers in Cell and Developmental Biology, October 2020, Frontiers

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  7. A Single Metabolite which Modulates Lipid Metabolism Alters Hematopoietic Stem/Progenitor Cell Behavior and Promotes Lymphoid Reconstitution

    Article • Stem Cell Reports, September 2020, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  8. Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression

    Article • Frontiers in Cell and Developmental Biology, July 2020, Frontiers

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  9. FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits

    Article • Cell Stem Cell, July 2020, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  10. High-throughput screening in multicellular spheroids for target discovery in the tumor microenvironment

    Article • Expert Opinion on Drug Discovery, May 2020, Taylor & Francis

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  11. A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF-mutated Melanoma to MAPK Inhibitors

    Article • Clinical Cancer Research, August 2019, American Association for Cancer Research (AACR)

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  12. BRAF inhibition sensitizes melanoma cells to α-amanitin via decreased RNA polymerase II assembly

    Article • Scientific Reports, May 2019, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  13. Correction of gene model annotations improves isoform abundance estimates: the example of ketohexokinase (Khk)

    Article • F1000Research, April 2019, Faculty of 1000, Ltd.

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  14. A manual update of genomic annotations improves isoform quantifications

    Article • F1000Research, December 2018, Faculty of 1000, Ltd.

    Christophe Chabbert, Tanja Eberhart, ILARIA GUCCINI, PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  15. Pexophagy in yeast and mammals: an update on mysteries

    Article • Histochemistry and Cell Biology, September 2018, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  16. A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity

    Article • Cell Reports, August 2017, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  17. Isolation of Peroxisomes from Mouse Brain Using a Continuous Nycodenz Gradient: A Comparison to the Isolation of Liver and Kidney Peroxisomes

    Article • January 2017, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  18. Erratum

    Article • Autophagy, February 2016, Taylor & Francis

    Dr Janos KristonVizi, Juan Segura-Aguilar, Professor Nektarios Tavernarakis, Dr Reinhard Dechant, Dr Vasilis J Promponas, Professor Marc Lecuit, Professor Paula I. Moreira, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Professor Jean-François Beaulieu, Shile Huang, Maria João Sousa, Professor Godefridus J Peters, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Professor Abdel Halim Harrath, Professor Günther Weindl

  19. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang, Professor George Perry, Professor Godefridus J Peters, Shuo-Chien Ling, Professor Jiwu Wei, Deepak Shukla

  20. EPAS1/HIF-2α is a driver of mammalian pexophagy

    Article • Autophagy, May 2015, Taylor & Francis

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  21. Hypoxia signaling pathways: modulators of oxygen-related organelles

    Article • Frontiers in Cell and Developmental Biology, January 2015, Frontiers

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  22. Hif-2α Promotes Degradation of Mammalian Peroxisomes by Selective Autophagy

    Article • Cell Metabolism, November 2014, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  23. Differential basolateral–apical distribution of scavenger receptor, class B, type I in cultured cells and the liver

    Article • Histochemistry and Cell Biology, July 2014, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  24. Cholesterol biosynthesis and ER stress in peroxisome deficiency

    Article • Biochimie, March 2014, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  25. Endoplasmic reticulum stress impairs cholesterol efflux and synthesis in hepatic cells

    Article • Journal of Lipid Research, October 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  26. High-density lipoprotein endocytosis in endothelial cells

    Article • World Journal of Biological Chemistry, January 2013, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  27. Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

    Article • Nature, December 2012, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  28. Peroxisome deficiency-induced ER stress and SREBP-2 pathway activation in the liver of newborn PEX2 knock-out mice

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, June 2012, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  29. Atherogenic diet leads to posttranslational down-regulation of murine hepatocyte SR-BI expression

    Article • Atherosclerosis, January 2009, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  30. Peroxisome Deficiency Causes a Complex Phenotype because of Hepatic SREBP/Insig Dysregulation Associated with Endoplasmic Reticulum Stress

    Article • Journal of Biological Chemistry, December 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  31. Additions and Corrections

    Article • Biology of Reproduction, February 2008, Oxford University Press (OUP)

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  32. Peroxisomes in Human and Mouse Testis: Differential Expression of Peroxisomal Proteins in Germ Cells and Distinct Somatic Cell Types of the Testis1

    Article • Biology of Reproduction, December 2007, Oxford University Press (OUP)

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  33. Differential expression of peroxisomal matrix and membrane proteins during postnatal development of mouse brain

    Article • The Journal of Comparative Neurology, November 2007, Wiley

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  34. Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes

    Article • Histochemistry and Cell Biology, December 2006, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  35. The hypolipidemic compound cetaben induces changes in Golgi morphology and vesicle movement

    Article • Histochemistry and Cell Biology, July 2004, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  36. Disturbed Cholesterol Homeostasis in a Peroxisome-Deficient PEX2 Knockout Mouse Model

    Article • Molecular and Cellular Biology, January 2004, ASM Journals

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  37. Cholesterol Biosynthesis and Regulation: Role of Peroxisomes

    Article • January 2003, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  38. Central role of peroxisomes in isoprenoid biosynthesis

    Article • Progress in Lipid Research, September 2002, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  39. Purification of brain peroxisomes and localization of 3-hydroxy-3-methylglutaryl coenzyme A reductase

    Article • European Journal of Biochemistry, September 2001, Wiley

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  40. Cetaben-induced changes on the morphology and peroxisomal enzymes in MH1C1 rat hepatoma cells and HepG2 human hepatoblastoma cells

    Article • Histochemistry and Cell Biology, June 2001, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  41. Localization of mRNAs encoding peroxisomal proteins in cell culture by non-radioactive in situ hybridization. Comparison of rat and human hepatoma cells and their responses to two divergent hypolipidemic drugs

    Article • Histochemistry and Cell Biology, June 2001, Springer Science + Business Media

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  42. Biogeography and phenotypic variation in Trichoderma sect. Longibrachiatum and associated Hypocrea species

    Article • Mycological Research, April 1997, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  43. Molecular evidence that the asexual industrial fungus Trichoderma reesei is a clonal derivative of the ascomycete Hypocrea jecorina.

    Article • Proceedings of the National Academy of Sciences, July 1996, Proceedings of the National Academy of Sciences

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  44. Cellulase Formation by Species ofTrichodermasect.Longibrachiatumand ofHypocreaspp. with Anamorphs Referable toTrichodermasect.Longibrachiatum

    Article • Fungal Genetics and Biology, June 1996, Elsevier

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs

  45. Differential Induction of Peroxisomal Enzymes by Hypolipidaemics in Human (HepG2) and Rat (MH1C1) Hepatoma Cell Lines

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 1995, De Gruyter

    PD Dipl.-Ing. Dr. techn. Werner J Kovacs