All Stories

  1. The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases

    Article • Cell Death and Differentiation, May 2019, Springer Science + Business Media

    Dr Francesca Finetti

  2. A T Cell Suppressive Circuitry Mediated by CD39 and Regulated by ShcC/Rai Is Induced in Astrocytes by Encephalitogenic T Cells

    Article • Frontiers in Immunology, May 2019, Frontiers

    Dr Francesca Finetti

  3. p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape

    Article • Haematologica, February 2019, Ferrata Storti Foundation (Haematologica)

    Dr Francesca Finetti

  4. The immunological synapse as a pharmacological target

    Article • Pharmacological Research, June 2018, Elsevier

    Dr Francesca Finetti

  5. Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes

    Article • Frontiers in Immunology, May 2018, Frontiers

    Dr Francesca Finetti

  6. Transcellular communication at the immunological synapse: a vesicular traffic-mediated mutual exchange

    Article • F1000Research, October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  7. Faculty of 1000 evaluation for Ciliary extracellular vesicles: txt msg organelles.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  8. Faculty of 1000 evaluation for Microtubule-associated protein-4 controls nanovesicle dynamics and T cell activation.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  9. Faculty of 1000 evaluation for Human T cell activation induces synaptic translocation and alters expression of the serine protease inhibitor neuroserpin and its target protease.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  10. Faculty of 1000 evaluation for The immune synapse clears and excludes molecules above a size threshold.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  11. Faculty of 1000 evaluation for Investigation of Content, Stoichiometry and Transfer of miRNA from Human Neural Stem Cell Line Derived Exosomes.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  12. Faculty of 1000 evaluation for Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  13. Faculty of 1000 evaluation for Sorting nexin 27 interactome in T-lymphocytes identifies zona occludens-2 dynamic redistribution at the immune synapse.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  14. Faculty of 1000 evaluation for HIV-1 Nef Impairs the Formation of Calcium Membrane Territories Controlling the Signaling Nanoarchitecture at the Immunological Synapse.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  15. Faculty of 1000 evaluation for B-cell agonists up-regulate AID and APOBEC3G deaminases, which induce IgA and IgG class antibodies and anti-viral function.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  16. Faculty of 1000 evaluation for HIV-1 Nef limits communication between linker of activated T cells and SLP-76 to reduce formation of SLP-76-signaling microclusters following TCR stimulation.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  17. Faculty of 1000 evaluation for Imaging of Cell-Cell Communication in a Vertical Orientation Reveals High-Resolution Structure of Immunological Synapse and Novel PD-1 Dynamics.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  18. Faculty of 1000 evaluation for Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  19. Faculty of 1000 evaluation for Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism.

    Article • October 2017, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  20. Faculty of 1000 evaluation for Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation.

    Article • October 2016, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  21. Faculty of 1000 evaluation for Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient mice.

    Article • June 2016, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  22. Vesicular Trafficking to the Immune Synapse: How to Assemble Receptor-Tailored Pathways from a Basic Building Set

    Article • Frontiers in Immunology, February 2016, Frontiers

    Dr Francesca Finetti

  23. Faculty of 1000 evaluation for Distinct Roles of Cytoskeletal Components in Immunological Synapse Formation and Directed Secretion.

    Article • October 2015, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  24. The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse

    Article • Journal of Cell Science, June 2015, The Company of Biologists

    Dr Francesca Finetti

  25. The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis

    Article • Cell Death and Differentiation, March 2015, Nature

    Dr Francesca Finetti

  26. Faculty of 1000 evaluation for Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.

    Article • February 2015, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  27. Regulation of Vesicular Traffic at the T Cell Immune Synapse: Lessons from the Primary Cilium

    Article • Traffic, January 2015, Wiley

    Dr Francesca Finetti

  28. Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system

    Article • Journal of Cell Science, February 2014, The Company of Biologists

    Dr Francesca Finetti

  29. Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc

    Article • Cell Death and Disease, February 2014, Nature

    Dr Francesca Finetti

  30. Faculty of 1000 evaluation for Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse.

    Article • November 2013, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  31. Faculty of 1000 evaluation for T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology.

    Article • January 2013, Faculty of 1000, Ltd.

    Dr Francesca Finetti

  32. Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium

    Article • Immunological Reviews, December 2012, Wiley

    Dr Francesca Finetti

  33. The Shc Family Protein Adaptor, Rai, Negatively Regulates T Cell Antigen Receptor Signaling by Inhibiting ZAP-70 Recruitment and Activation

    Article • PLoS ONE, December 2011, PLOS

    Dr Francesca Finetti

  34. The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of TH17 cell development

    Article • Journal of Allergy and Clinical Immunology, June 2011, Elsevier

    Dr Francesca Finetti

  35. TheBordetella pertussisadenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse

    Article • The Journal of Cell Biology, May 2011, Rockefeller University Press

    Dr Francesca Finetti

  36. TheBordetella pertussisadenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse

    Article • The Journal of Experimental Medicine, May 2011, Rockefeller University Press

    Dr Francesca Finetti

  37. Intraflagellar transport: a new player at the immune synapse

    Article • Trends in Immunology, April 2011, Elsevier

    Dr Francesca Finetti

  38. Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia

    Article • Blood, January 2010, American Society of Hematology

    Dr Francesca Finetti

  39. Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters

    Article • Immunological Reviews, November 2009, Wiley

    Dr Francesca Finetti

  40. Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse

    Article • Nature Cell Biology, October 2009, Springer Science + Business Media

    Dr Giuseppe Perinetti, Dr Francesca Finetti

  41. The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects inCol6a1−/−myopathic mice

    Article • British Journal of Pharmacology, July 2009, Wiley

    Dr Francesca Finetti

  42. The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity

    Article • Blood, May 2008, American Society of Hematology

    Dr Francesca Finetti

  43. p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis

    Article • Cell Death and Differentiation, June 2006, Nature

    Dr Francesca Finetti

  44. Molecular modelling of S1 and S2 subunits of SARS coronavirus spike glycoprotein

    Article • Biochemical and Biophysical Research Communications, October 2003, Elsevier

    Dr Francesca Finetti