All Stories

  1. The Role of Unmethylated 5′-C-Phosphate-G-3′ (CpG) Motifs in Mitochondrial and Bacterial DNA in the Pathogenesis of Alzheimer’s Disease
  2. Amyloid-β and phosphorylated-tau accumulation in retrosplenial cortex of young Alzheimer's disease model: Impact on network activity
  3. Recommendations for reporting findings from analyses using artificial intelligence and machine learning in the Journal of Alzheimer's Disease
  4. The Amyloid Cascade Hypothesis
  5. Conventional and Emerging Drug Targeting Sites in Alzheimer’s Disease and the Role of Translational Informatics in its Diagnosis and Management
  6. Is US residence a risk factor for Alzheimer's disease?
  7. Potential Effects of Glucagon-Like Peptide-1 Receptor Agonists in Patients With Diabetes and High Risk for Dementia
  8. Hyperphosphorylated Tau Induces Cortical Hypoexcitability in Transgenic Mouse Models: A Meta-Analysis
  9. Living the examined life Ninety-Nine Lessons in Critical Thinking by Robert FriedlandP.Oxford University Press, 2025, 285 pp.
  10. Identifying patients with mild cognitive impairment at high risk of transitioning to Alzheimer's disease using routinely collected data
  11. Associations of semaglutide with Alzheimer's disease-related dementias in patients with type 2 diabetes: A real-world target trial emulation study
  12. Assessment of X Chromosome Centromere Instability in Alzheimer’s Disease: A Quantitative FISH Approach
  13. Association of Polygenic Risk Score for 5 Diseases With Alzheimer Disease Progression, Biomarkers, and Amyloid Deposition
  14. Inspecting the Triazole Scaffold as Powerful Antifibril Agents against 2N4R Tau and α-Synuclein Aggregates
  15. In data we trust. Book review: “Piller Charles. Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s” PillerCharles (2025). Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s. One...
  16. Exploring nutritional supplement use for countering respiratory tract infections through an X (formerly Twitter)-based survey
  17. Progesterone induction of tau phosphorylation during the differentiation of human embryonic stem cells into neuroectodermal rosettes
  18. Assessment of X Chromosome Centromere Instability in Alzheimer’s Disease: A Quantitative FISH Approach
  19. Associations of semaglutide with first‐time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real‐world data in the US
  20. Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics
  21. Endocrine Dyscrasia in the Etiology and Therapy of Alzheimer’s Disease
  22. Fueling Alzheimer’s Disease: Where Does Immunometabolism Stand?
  23. Central role of brain regulatory T cells in the inflammatory cascade in Alzheimer’s disease
  24. JAD’s Glorious 100 Volumes
  25. Alzheimer’s Amyloid Hypothesis and Antibody Therapy: Melting Glaciers?
  26. Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues
  27. Fabrication and Characterization of Quad-Component Bioinspired Hydrogels to Model Elevated Fibrin Levels in Central Nervous Tissue Scaffolds
  28. Living Up to the Promise of Preventing Dementia
  29. Letter to the Editor: First Experiences with Amyloid-Related Imaging Abnormalities – Yet without Imaging that Can Rule Out Cerebral Injury or Monitor Efficacy of Recommended Management
  30. Revision of Alzheimer’s diagnostic criteria or relocation of the Potemkin village
  31. Association of COVID-19 with Risk and Progression of Alzheimer’s Disease: Non-Overlapping Two-Sample Mendelian Randomization Analysis of 2.6 Million Subjects
  32. Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on α-Synuclein and Tau Aggregation
  33. MicroRNA networks linked with BRCA1/2, PTEN, and common genes for Alzheimer's disease and breast cancer share highly enriched pathways that may unravel targets for the AD/BC comorbidity treatment
  34. Slowing the Clock of Life
  35. Passive Alzheimer’s immunotherapy: A promising or uncertain option?
  36. Roles of Oxidative Stress in Synaptic Dysfunction and Neuronal Cell Death in Alzheimer’s Disease
  37. Exploring Molecular Targets for Mitochondrial Therapies in Neurodegenerative Diseases
  38. The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes
  39. Memory, Sleep, and Tau Function
  40. FDG-PET versus Amyloid-PET Imaging for Diagnosis and Response Evaluation in Alzheimer’s Disease: Benefits and Pitfalls
  41. Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease
  42. The amyloid-β pathway in Alzheimer's disease: a plain language summary
  43. The retina-brain axis and diabetic retinopathy
  44. Universal research index: An inclusive metric to quantify scientific research output
  45. Playing Russian Roulette with Alzheimer’s Disease Patients: Do the Cognitive Benefits of Lecanemab Outweigh the Risk of Edema, Stroke and Encephalitis?
  46. Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer’s disease brain
  47. Circulating long non-coding RNAs as novel diagnostic biomarkers for Alzheimer’s disease (AD): A systematic review and meta-analysis
  48. Alzheimer’s Disease: Not Just for the Aged?
  49. Beyond the Clouds: B.R. Brinkley (1936-2020)
  50. The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis
  51. The Teflon hypothesis
  52. Synthesize heterogeneous biological knowledge via representation learning for Alzheimer’s disease drug repurposing
  53. Natural Product Co-Metabolism and the Microbiota–Gut–Brain Axis in Age-Related Diseases
  54. MRI Monitoring of Anti-Alzheimer Therapy Amyloid-Related Imaging Abnormalities: Due Diligence or Overkill?
  55. Retinal neurodegeneration in euglycemic hyperinsulinemia, prediabetes, and diabetes
  56. Mouse and Human Tau Expression in Different Brain Areas
  57. Therapeutic Antiaging Strategies
  58. Neuropathologic Changes Provide Insights into Key Mechanisms of Alzheimer Disease and Related Dementia
  59. Making the Case for Accelerated Withdrawal of Aducanumab
  60. Hyperphosphorylated Tau Relates to Improved Cognitive Performance and Reduced Hippocampal Excitability in the Young rTg4510 Mouse Model of Tauopathy
  61. Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria
  62. Now is the Time to Improve Cognitive Screening and Assessment for Clinical and Research Advancement
  63. Multi-Task Graph Neural Network For Alzheimer’s Disease Drug Repurposing Using Knowledge Graph And Multi-Level Evidence
  64. Optogenetics: implications for Alzheimer’s disease research and therapy
  65. Editorial: Oxidative Stress Revisited—Major Role in Vascular Diseases, Volume II
  66. SWADESH: A Comprehensive Platform for Multimodal Data and Analytics for Advanced Research in Alzheimer’s Disease and Other Brain Disorders
  67. Conformation- and phosphorylation-dependent electron tunnelling across self-assembled monolayers of tau peptides
  68. Alzheimer’s Disease Pharmacology
  69. Functional study in the young rTg4510 mouse model of tauopathy
  70. American Dementia: Brain Health in an Unhealthy Society by Daniel R. George and Peter J. Whitehouse, Johns Hopkins Press, 2021, 390 pp.
  71. The Amyloid-β Pathway in Alzheimer’s Disease
  72. Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease
  73. Omics sciences for systems biology in Alzheimer’s disease: State-of-the-art of the evidence
  74. Community Engagement Practices at Research Centers in U.S. Minority Institutions: Priority Populations and Innovative Approaches to Advancing Health Disparities Research
  75. Oxidative Stress Signaling in Blast TBI-Induced Tau Phosphorylation
  76. Biogenic metallic elements in the human brain?
  77. Challenges and Strategies of Successful Mentoring: The Perspective of LEADS Scholars and Mentors from Minority Serving Institutions
  78. Reactive Oxygen Species and Their Impact in Neurodegenerative Diseases: Literature Landscape Analysis
  79. MMR Vaccination: A Potential Strategy to Reduce Severity and Mortality of COVID-19 Illness
  80. Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy
  81. Corrigendum to “Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer’s Disease”
  82. Alzheimer’s and Consciousness: How Much Subjectivity Is Objective?
  83. A brief guide to the science and art of writing manuscripts in biomedicine
  84. The Interrelation of Neurological and Psychological Symptoms of COVID-19: Risks and Remedies
  85. Decreased salivary lactoferrin levels are specific to Alzheimer's disease
  86. Alzheimer’s Disease Patients in the Crosshairs of COVID-19
  87. Role of antioxidants and a nutrient rich diet in Alzheimer's disease
  88. Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances
  89. The Role of the Microbiota–Gut–Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases
  90. The Microbiota–Gut–Brain Axis–Heart Shunt Part II: Prosaic Foods and the Brain–Heart Connection in Alzheimer Disease
  91. Polyphenols in Alzheimer’s Disease and in the Gut–Brain Axis
  92. Hippocampal Unicellular Recordings and Hippocampal-dependent Innate Behaviors in an Adolescent Mouse Model of Alzheimer’s disease
  93. TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease
  94. Dementia Pugilistica Revisited
  95. Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury
  96. No Evidence of Chronic Traumatic Encephalopathy Pathology or Increased Neurodegenerative Proteinopathy in Former Military Service Members
  97. Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges
  98. The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features
  99. Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury
  100. Biomarker-guided clustering of Alzheimer's disease clinical syndromes
  101. Current research in biotechnology: Exploring the biotech forefront
  102. Chronic traumatic encephalopathy neuropathology might not be inexorably progressive or unique to repetitive neurotrauma
  103. TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration
  104. Gait Disorders in Alzheimer’s Disease and Other Dementias: There is Something in the Way You Walk
  105. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study
  106. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies
  107. Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry
  108. Differences in structure and function between human and murine tau
  109. Neuropsychiatric Disturbances and Diabetes Mellitus: The Role of Oxidative Stress
  110. Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders
  111. The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation
  112. Editorial: Oxidative Stress Revisited—Major Role in Vascular Diseases
  113. Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice
  114. Lithium as a Treatment for Alzheimer’s Disease: The Systems Pharmacology Perspective
  115. MAPK signalling pathway in cancers: Olive products as cancer preventive and therapeutic agents
  116. Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease
  117. Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease
  118. Rapid method towards proteomic analysis of dried blood spots by MALDI mass spectrometry
  119. Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3
  120. Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer’s Precision Medicine and Pharmacology
  121. The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation.
  122. The Alzheimer Precision Medicine Initiative
  123. The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research
  124. No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study
  125. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases
  126. Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study
  127. The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease
  128. Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges
  129. COMMENTARY: DEVELOPMENT OF THE BLOOD-BASED ALZHEIMER’S DISEASE LIQUID BIOPSY
  130. Preface
  131. Vascular Oxidative Stress: Impact and Therapeutic Approaches
  132. Preface
  133. An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson’s Disease1
  134. Genetic Risk of Alzheimer’s Disease: Three Wishes Now That the Genie is Out of the Bottle
  135. From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors
  136. Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
  137. Basal Forebrain Volume, but Not Hippocampal Volume, Is a Predictor of Global Cognitive Decline in Patients With Alzheimer's Disease Treated With Cholinesterase Inhibitors
  138. Association of cerebrospinal fluid α‐synuclein with total and phospho‐tau 181 protein concentrations and brain amyloid load in cognitively normal subjective memory complainers stratified by Alzheimer's disease biomarkers
  139. Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints
  140. Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology
  141. Role of Amyloid-β and Tau Proteins in Alzheimer’s Disease: Confuting the Amyloid Cascade
  142. Preface
  143. Gibbs Free-Energy Gradient along the Path of Glucose Transport through Human Glucose Transporter 3
  144. Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model
  145. Drug-Abuse Nanotechnology: Opportunities and Challenges
  146. Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data
  147. Pathomechanisms of TDP-43 in neurodegeneration
  148. Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders
  149. Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer’s Disease
  150. Precision pharmacology for Alzheimer’s disease
  151. Expression of growth hormone gene in the baboon eye
  152. Towards an Integrative Understanding of tRNA Aminoacylation–Diet–Host–Gut Microbiome Interactions in Neurodegeneration
  153. Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders
  154. Birth of JAD: 20 Years Later
  155. Anthocyanins and its biological & therapeutic characters
  156. Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-β Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer’s Disease Pathology
  157. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex
  158. Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens
  159. Iron·ic facts about dementia
  160. Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer’s Diseased Brains by MALDI-TOF MS with MS/MS
  161. Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers
  162. Preface
  163. Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects
  164. Foreword
  165. Incubation with Cu(II) and Zn(II) salts enhances MALDI-TOF mass spectra of amyloid-beta and α-synuclein toward in vivo analysis
  166. Thermodynamics of Amyloid-β Fibril Elongation: Atomistic Details of the Transition State
  167. Preface
  168. Affinity and path of binding xylopyranose unto E. coli xylose permease
  169. The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features
  170. Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer’s Disease
  171. Dementia Pugilistica Revisited
  172. Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study
  173. Advances in Alzheimer’s Diagnosis and Therapy: The Implications of Nanotechnology
  174. Asking the Right Questions
  175. BARHL1 Is Downregulated in Alzheimer’s Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways
  176. Molecular Pathways in Normal Aging and Neurodegeneration: Mechanisms and Therapeutics
  177. Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders
  178. Inhibition of mitochondrial fragmentation protects against Alzheimer’s disease in rodent model
  179. TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer’s Disease
  180. Meet Our Editor
  181. The Vascular Impairment of Cognition Classification Consensus Study
  182. Elongation affinity, activation barrier, and stability of Aβ42 oligomers/fibrils in physiological saline
  183. Nutritional supplements and dementia
  184. Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer’s Disease
  185. Meet Our Editor
  186. Meet Our Co-Editor
  187. Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer’s disease
  188. Metals and Mitochondria in Neurodegeneration
  189. Brain Composition: Age-Related Changes ☆
  190. Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer’s Disease
  191. Tau Proteins
  192. Microbes and Alzheimer's Disease
  193. Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease
  194. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology
  195. Functional and Genomic Features of Human Genes Mutated in Neuropsychiatric Disorders
  196. Modulation of Parkinson’s Disease Associated Protein Rescues Alzheimer’s Disease Degeneration
  197. Meet Our Associate Editor
  198. The Role of the Iron Stain in Assessing Intracranial Hemorrhage
  199. Promise from the Sea
  200. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks
  201. Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue
  202. Oxidative Stress Induces Senescence in Cultured RPE Cells
  203. Meet Our Editorial Board Member:
  204. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein
  205. Nucleic acid oxidative damage in Alzheimer's disease—explained by the hepcidin-ferroportin neuronal iron overload hypothesis?
  206. Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities
  207. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer’s disease
  208. Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse
  209. Meta-analysis of Telomere Length in Alzheimer’s Disease
  210. Microbes and Alzheimer’s Disease
  211. Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease
  212. Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer’s Brains
  213. Telomere length in Parkinson's disease: A meta-analysis
  214. Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer’s disease
  215. 1,3-propanediol binds deep inside the channel to inhibit water permeation through aquaporins
  216. Current needs for human and medical genomics research infrastructure in low and middle income countries: Table 1
  217. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
  218. Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβby Using Several Synthetic and Herbal Compounds
  219. Editor Note on Mass Spectra for Revealing Disease - Associated Pathways
  220. Management of Neuro Degenerative Diseases of Elderly Adults
  221. Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles
  222. Tackling Alzheimer’s Disease by Targeting Oxidative Stress and Mitochondria
  223. Oxidative Stress and Alzheimer’s Disease
  224. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease
  225. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer’s disease
  226. Recent Advances in Medicinal Chemistry
  227. Alterations of the X Chromosome in Lymphocytes of Alzheimer’s Disease Patients
  228. A Cultivated Form of a Red Seaweed (Chondrus crispus), Suppresses β-Amyloid-Induced Paralysis in Caenorhabditis elegans
  229. Redox Status and Neuro Inflammation Indexes in Cerebellum and Motor Cortex of Wistar Rats Supplemented with Natural Sources of Omega-3 Fatty Acids and Astaxanthin: Fish Oil, Krill Oil, and Algal Biomass
  230. Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point
  231. Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis
  232. Meet Our Editorial Board Member:
  233. Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer d...
  234. Oxidative damage is correlated with mitochondrial autophagy
  235. Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells
  236. Chronic Effects of Mild Neurotrauma
  237. Miro1 deficiency in amyotrophic lateral sclerosis
  238. Meet Our Editorial Board Member:
  239. Posttranslational modifications of α-tubulin in alzheimer disease
  240. From Neurodegeneration to Brain Health: An Integrated Approach
  241. Curcumin/Melatonin Hybrid 5-(4-Hydroxy-phenyl)-3-oxo-pentanoic Acid [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-amide Ameliorates AD-Like Pathology in the APP/PS1 Mouse Model
  242. Alternative neural circuitry that might be impaired in the development of Alzheimer disease
  243. Raúl Mena: 1953–2014
  244. Meet the Editorial Board
  245. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-β and Phosphorylated Tau
  246. Overview
  247. Two Hundred Treasured Issues!
  248. Neuropathology and Ophthalmic Pathology
  249. Cerebrovascular and mitochondrial abnormalities in Alzheimer’s disease: a brief overview
  250. A Clinical Study of Lupron Depot in the Treatment of Women with Alzheimer's Disease: Preservation of Cognitive Function in Patients Taking an Acetylcholinesterase Inhibitor and Treated with High Dose Lupron Over 48 Weeks
  251. Cellular Pathology of Alzheimer Disease
  252. Editor Note
  253. Low Dose Pioglitazone Attenuates Oxidative Damage in Early Alzheimer's Disease by Binding mitoNEET
  254. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-β and Phosphorylated Tau
  255. Global warming and neurodegenerative disorders: speculations on their linkage
  256. Islet Amyloid Polypeptide (IAPP): A Second Amyloid in Alzheimer's Disease
  257. Precision medicine using individualized biosimulations of drug dosing: Alzheimer's disease
  258. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease
  259. Recent Advances in Medicinal Chemistry
  260. Preface
  261. Parallels Between Major Depressive Disorder and Alzheimer’s Disease: Role of Oxidative Stress and Genetic Vulnerability
  262. Cognitive impairment in multiple system atrophy: A position statement by the neuropsychology task force of the MDS multiple system atrophy (MODIMSA) study group
  263. Accumulation of Intraneuronal Amyloid-β is Common in Normal Brain
  264. The complexities of the pathology–pathogenesis relationship in Alzheimer disease
  265. Plaques and tangles: Birthmarks of the aging soul
  266. Neuronal failure in Alzheimer’s disease: a view through the oxidative stress looking-glass
  267. Low Plasma Leptin in Cognitively Impaired ADNI Subjects: Gender Differences and Diagnostic and Therapeutic Potential
  268. Ethics Review as a Catalyst for Progress
  269. A New Outlook for Alzheimer’s Disease
  270. Phosphorylation of tau protein at sites Ser396-404is one of the earliest events in Alzheimer's disease and Down syndrome
  271. Methemoglobinemia—A biomarker and a link to ferric iron accumulation in Alzheimer’s disease
  272. Looking at Alzheimer‘s disease from a different angle
  273. Apolipoprotein E4 Prevents Growth of Malaria at the Intraerythrocyte Stage: Implications For Diff erences in Racial Susceptibility to Alzheimer’s Disease
  274. Neuropsychiatric genetics in developing countries: Current challenges
  275. Differential Network Analyses of Alzheimer’s Disease Identify Early Events in Alzheimer’s Disease Pathology
  276. Preface
  277. Pathogenesis of Alzheimer’s Disease
  278. Recent Advances in Medicinal Chemistry
  279. Neuropathology of Alzheimer's Disease
  280. Proteolytic Cleavage of Polymeric Tau Protein by Caspase-3: Implications for Alzheimer Disease
  281. Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer’s and other neurodegenerative diseases
  282. A Low-Molecular-Weight Ferroxidase Is Increased in the CSF of sCJD Cases: CSF Ferroxidase and Transferrin as Diagnostic Biomarkers for sCJD
  283. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: A meta-analysis
  284. Faculty of 1000 evaluation for Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.
  285. Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer’s brain
  286. Tryptamine Induces Axonopathy and Mitochondriopathy Mimicking Neurodegenerative Diseases via Tryptophanyl-tRNA Deficiency
  287. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease?
  288. Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance
  289. Larry Sparks: Innovator and Iconoclast
  290. Modification of Amyloid-β1-42 Fibril Structure by Methionine-35 Oxidation
  291. Amyloid β peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system
  292. Presenilin mutations impair mitochondrial dynamics in neurons
  293. Neuronal leptin resistance in Alzheimer's disease
  294. Methemoglobin catabolism and Alzheimer's disease
  295. Flux and metabolite pathway mapping in the aging and Alzheimer's disease hippocampus
  296. Mitochondrial DNA Oxidative Damage and Repair in Aging and Alzheimer's Disease
  297. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links
  298. Are Alzheimer's Disease and Aging Evolutionary?
  299. Mitochondrial Abnormalities in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease
  300. The Structures of the E22Δ Mutant-Type Amyloid-β Alloforms and the Impact of E22Δ Mutation on the Structures of the Wild-Type Amyloid-β Alloforms
  301. Tackling the Elusive Challenges Relevant to Conquering the 100-Plus Year Old Problem of Alzheimer’s Disease
  302. Tackling the Elusive Challenges Relevant to Conquering the 100-Plus Year Old Problem of Alzheimer's Disease
  303. Phosphorylation of Tau Protein as the Link between Oxidative Stress, Mitochondrial Dysfunction, and Connectivity Failure: Implications for Alzheimer’s Disease
  304. Nutrients and Food Constituents in Cognitive Decline and Neurodegenerative Disease
  305. Foreword (The Largest Unmet Market: Chronic Diseases of Aging)
  306. DNA Damage in Alzheimer Disease Lymphocytes and Its Relation to Premature Centromere Division
  307. Deconstructing Mitochondrial Dysfunction in Alzheimer Disease
  308. Cloning’s Promise
  309. Oxidative Stress and Alzheimer’s Disease
  310. Abnormal Mitochondrial Dynamics in the Pathogenesis of Alzheimer's Disease
  311. Preface
  312. Abnormal Mitochondrial Dynamics in the Pathogenesis of Alzheimer's Disease
  313. Alzheimer's Disease: Advances for a New Century
  314. Imaging the Onset and Progression of Alzheimer's Disease: Implications for Prevention Trials
  315. Inge Grundke-Iqbal: A Legacy of Tau in the Etiology of Alzheimer Disease (1937–2012)
  316. Foreword [The Largest Unmet Market: Chronic Diseases of Aging]
  317. Foreword [The Largest Unmet Market: Chronic Diseases of Aging]
  318. Isotyping the Human TOMM40 Variable-Length Polymorphism by Gene Amplification and Restriction Digest
  319. The impairment of insulin signaling in Alzheimer's disease
  320. Pathogenesis and Disease-modifying Therapy in Alzheimer's Disease: The Flat Line of Progress
  321. Editorial - Chronic or Late Lyme Neuroborreliosis: Present and Future
  322. Editorial [Special Issue in Honor of the 70th Birthday of Dr. Atta-ur-Rahman, FRS]
  323. Mark Smith: Pioneer of Alzheimer Disease Research
  324. β-Amyloid 1-42 induces physiological transcriptional regulation of BACE1
  325. Reanimating basal forebrain cholinergic neurons in electrophysiology biosimulations using COPASI software
  326. LRRK2 Directly Interacts with DLP1 to Regulate Mitochondrial Dynamics and Function
  327. Journal of Huntington's Disease – The Family Gets Bigger
  328. R-_-Lipoic Acid as a Potent Agent of Mitochondrial Protectionin Alzheimer’s Disease
  329. Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-β(1–40) and zinc(II)-bound amyloid-β(1–42) with dynamics
  330. Oxidative Damage to RNA in Aging and Neurodegenerative Disorders
  331. Molecular neuropathogenesis of Alzheimer’s disease: an interaction model stressing the central role of oxidative stress
  332. Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer’s disease
  333. Nanoparticle Delivery of Transition-Metal Chelators to the Brain: Oxidative Stress will Never See it Coming!
  334. Guidelines for the use and interpretation of assays for monitoring autophagy
  335. Therapeutic Opportunities in Alzheimer Disease: Current Concepts
  336. Association of Mitochondrial Signaling in Alzheimer’s Disease and Hypoxia
  337. Nanoparticle-iron Chelator Conjugates as Multifunctional Disease-modifying Drugs for Prevention and Treatment of Alzheimer’s Disease
  338. The role of iron as a mediator of oxidative stress in Alzheimer disease
  339. The Earliest Stage of Cognitive Impairment in Transition From Normal Aging to Alzheimer Disease Is Marked by Prominent RNA Oxidation in Vulnerable Neurons
  340. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover
  341. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease
  342. Neuroinflammation, Hyperphosphorylated Tau, Diffuse Amyloid Plaques, and Down-Regulation of the Cellular Prion Protein in Air Pollution Exposed Children and Young Adults
  343. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1
  344. The Contribution of the Amyloid Hypothesis to the Understanding of Alzheimer's Disease: A Critical Overview
  345. Pharmaceutical Regulation: Crossroad of Opportunity as the Distinction between Food and Drugs Blurs
  346. Mitochondrial Importance in Alzheimer’s, Huntington’s and Parkinson’s Diseases
  347. Mark A. Smith: neurocytochemistry innovator
  348. Glycogen Synthase Kinase 3: A Point of Integration in Alzheimer's Disease and a Therapeutic Target?
  349. Editors & Editorial Board
  350. Doβ-Defensins and Other Antimicrobial Peptides Play a Role in Neuroimmune Function and Neurodegeneration?
  351. Amyloid Beta and Tau Proteins as Therapeutic Targets for Alzheimer’s Disease Treatment: Rethinking the Current Strategy
  352. Alzheimer's Disease and Vascular Deficiency: Lessons from Imaging Studies and Down Syndrome
  353. AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation
  354. A Pleotrophic Age for Alzheimer and Parkinson disease
  355. Editorial (A New Era for Medicinal Chemistry)
  356. Thinking Outside the Box in Alzheimer Disease Treatment
  357. Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease
  358. In Vivo and In Silico Evidence: Hippocampal Cholesterol Metabolism Decreases with Aging and Increases with Alzheimers Disease -- Modeling Brain Aging and Disease
  359. Intrahippocampal Amyloid-β (1-40) Injections Injure Medial Septal Neurons in Rats
  360. Amyloid-β peptide structure in aqueous solution varies with fragment size
  361. Cellular prion protein is essential for oligomeric amyloid- -induced neuronal cell death
  362. Imaging the Alzheimer Brain
  363. A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules
  364. New Insights into the Mechanisms of Mitochondrial Preconditioning-Triggered Neuroprotection
  365. The Mitochondrial Dynamics of Alzheimers Disease and Parkinsons Disease Offer Important Opportunities for Therapeutic Intervention
  366. Oxidative Stress and Balance in Neurodegenerative Diseases
  367. Mark A. Smith: The Scientist, the Man
  368. Faculty of 1000 evaluation for Iron(II) binding to amyloid-β, the Alzheimer's peptide.
  369. Pathological phenotype in familial neurodegenerative disease: implications for families and therapeutic constructs
  370. In Memoriam: Mark A. Smith, PhD
  371. Alzheimer’s disease therapy: a moving target
  372. A Novel Perspective on Tau in Alzheimers Disease
  373. Neurofilamentopathy in Neurodegenerative Diseases
  374. In Memoriam: Mark A. Smith, PhD: Neuroscientist and Visionary
  375. The origin of oxidative stress in neurodegenerative disease: Mark Anthony Smith 1965–2010
  376. The Cell Cycle Regulator Phosphorylated Retinoblastoma Protein Is Associated With Tau Pathology in Several Tauopathies
  377. Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease
  378. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson’s disease
  379. Journal of Parkinson's Disease – Birth of JAD's New Sister
  380. Mark A. Smith, PhD: Renegade Scientist and Visionary
  381. Facilitated Neurogenesis in the Developing Hippocampus After Intake of Theanine, an Amino Acid in Tea Leaves, and Object Recognition Memory
  382. Launch of ‘Atlas Journal of Medical and Biological Sciences’
  383. Drug Discovery for Neurodegenerative Diseases: Challenges and Novel Biochemical Targets
  384. Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?
  385. Mark Anthony Smith (1965–2010): Visionary, Alzheimer Researcher, and Editor-in-Chief of the Journal of Alzheimer's Disease
  386. The concept of redox balance in Alzheimer's disease: Mark Anthony Smith 1965–2010
  387. Neurodegenerative processes in Alzheimer’s disease: an overview of pathogenesis with strategic biomarker potential
  388. Modeling cholesterol metabolism by gene expression profiling in the hippocampus
  389. Role of metal dyshomeostasis in Alzheimer's disease
  390. Oxidative Stress in Alzheimer’s Disease: A Critical Appraisal of the Causes and the Consequences
  391. Mark A. Smith
  392. Transcriptome-To-Metabolome™ Biosimulation Reveals Human Hippocampal Hypometabolism with Age and Alzheimer’s Disease
  393. Unveiling “The Switch” from Aging to Alzheimer's Disease with the Senescence-Accelerated Mouse Model (SAMP8)
  394. Mathematical modeling of microtubule dynamics: Insights into physiology and disease
  395. Upregulation of Presenilin 1 in Brains of Sporadic, Late-Onset Alzheimer's Disease
  396. Oxidative Stress and Alzheimer Disease: Mechanisms and Therapeutic Opportunities
  397. CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s disease
  398. Faculty of 1000 evaluation for The prion protein as a receptor for amyloid-beta.
  399. Potential Role of Iron in a Mediterranean-style Diet
  400. Faculty of 1000 evaluation for Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis.
  401. Faculty of 1000 evaluation for Microtubule destruction induces tau liberation and its subsequent phosphorylation.
  402. Frontiers in Alzheimer’s disease therapeutics
  403. Oxidative stress in Alzheimer disease: A possibility for prevention
  404. Variably protease-sensitive prionopathy: A new sporadic disease of the prion protein
  405. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease
  406. Elevation of β-Amyloid 1-42 Autoantibodies in the Blood of Amnestic Patients With Mild Cognitive Impairment
  407. Total antioxidant status in newly diagnosed Alzheimer's patients: Population based study
  408. Paraffin-embedded tissue (PET) blot method: Application to Alzheimer disease
  409. Lipid peroxidation markers are associated with granulovacuolar degeneration but not lipofuscin formation
  410. Disturbance in AMP-activated protein kinase (AMPK) signaling pathway in Alzheimer's disease
  411. Autophagy in Alzheimer’s disease
  412. Antioxidant approaches for the treatment of Alzheimer’s disease
  413. ADF/cofilin-actin rods and synaptic loss in Alzheimer's disease
  414. The Importance of Histochemical Detection of Oxidative Damage in Tissue
  415. Hydroxynonenal-Generated Crosslinking Fluorophore and Mitochondria-derived Lipoic Acid Accumulation in Alzheimer Disease Reveal a Dichotomy of Protein Turnover
  416. A Synergistic Dysfunction of Mitochondrial Fission/Fusion Dynamics and Mitophagy in Alzheimer's Disease
  417. Mitochondria and Neurodegenerative Diseases
  418. Mitochondria: The Missing Link Between Preconditioning and Neuroprotection
  419. SU‐GG‐T‐341: Initial Results of Real‐Time External Surface Motion and Dose Monitoring Study for Lung Patients
  420. Causes versus effects: the increasing complexities of Alzheimer’s disease pathogenesis
  421. A Novel Endogenous Indole Protects Rodent Mitochondria and Extends Rotifer Lifespan
  422. Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid
  423. Divalent metal transporter, iron and Parkinson's disease: A pathological relationship
  424. Prospects on the Origin of Alzheimer's disease
  425. Widespread distribution of reticulon-3 in various neurodegenerative diseases
  426. NMR Studies of Zinc, Copper, and Iron Binding to Histidine, the Principal Metal Ion Complexing Site of Amyloid-β Peptide
  427. William R. Markesbery, M.D.: A Tribute
  428. Intraneuronal amyloid β accumulation and oxidative damage to nucleic acids in Alzheimer disease
  429. Mitochondrial Dynamics in Alzheimerʼs Disease
  430. Memantine
  431. Biomarkers in Alzheimer’s disease: past, present and future
  432. Abnormal Mitochondrial Dynamics—A Novel Therapeutic Target for Alzheimer's Disease?
  433. Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment
  434. Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells
  435. Abnormal mitochondrial dynamics and neurodegenerative diseases
  436. Signaling effect of amyloid-β42 on the processing of AβPP
  437. Oxidative Stress and Neurodegeneration: An Inevitable Consequence of Aging? Implications for Therapy
  438. Mitochondrial preconditioning: a potential neuroprotective strategy
  439. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
  440. Mitochondria: A therapeutic target in neurodegeneration
  441. Editors & Editorial Board
  442. Dissociated amyloid-β antibody levels as a serum biomarker for the progression of Alzheimer’s disease: A population-based study
  443. Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers
  444. Chapter 19. Targeting Oxidative Mechanisms in Alzheimer Disease
  445. Amyloid-β-Derived Diffusible Ligands Cause Impaired Axonal Transport of Mitochondria in Neurons
  446. Mitochondrial Drugs for Alzheimer Disease
  447. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets
  448. Natural Oxidant Balance in Parkinson Disease
  449. Nanoparticle and Iron Chelators as a Potential Novel Alzheimer Therapy
  450. Detection and Localization of Markers of Oxidative Stress by In Situ Methods: Application in the Study of Alzheimer Disease
  451. All-transretinoic acid as a novel therapeutic strategy for Alzheimer’s disease
  452. 2009 Award Recipients-Peter C. Burger, MD, Pierluigi Gambetti, MD, and Nicholas K. Gonatas, MD
  453. Insulin is a Two-Edged Knife on the Brain
  454. Evidence for Oxidative Damage in the Autistic Brain
  455. Food Antioxidants and Alzheimer’s Disease
  456. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia
  457. Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease
  458. Reexamining Alzheimer's Disease: Evidence for a Protective Role for Amyloid-β Protein Precursor and Amyloid-β
  459. Preventative effect of mitochondrial antioxidants in apoe deficiency mouse model of brain hypoperfusion
  460. Is oxidative stress an initiator of mitochondrial failure and vascular hypoperfusion during aging and Alzheimer disease? Present and future
  461. Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease
  462. Autophagocytosis of mitochondria is prominent in Alzheimer disease
  463. Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
  464. Hydroxynonenal generated crosslinking fluorophores accumulate in Alzheimer's disease
  465. Dissociated Aβ antibody level in newly diagnosed Alzheimer's disease: A population-based study
  466. Tau - an inhibitor of deacetylase HDAC6 function
  467. Metal Chelators Coupled with Nanoparticles as Potential Therapeutic Agents for Alzheimer's Disease
  468. Oxidative Stress in Parkinson`s Disease
  469. Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation
  470. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease
  471. Nanoparticle–chelator conjugates as inhibitors of amyloid-β aggregation and neurotoxicity: A novel therapeutic approach for Alzheimer disease
  472. Getting the iron out: Phlebotomy for Alzheimer’s disease?
  473. Leptin: A Novel Therapeutic Strategy for Alzheimer's Disease
  474. Oxidative Stress in Diabetes and Alzheimer's Disease
  475. The Neuroscience Peer Review Consortium
  476. A novel approach to the identification and quantitative elemental analysis of amyloid deposits—Insights into the pathology of Alzheimer’s disease
  477. Molecular Pathogenesis of Alzheimer’s Disease: Reductionist versus Expansionist Approaches
  478. RNA oxidation in Alzheimer disease and related neurodegenerative disorders
  479. The Neuroscience Peer Review Consortium
  480. The Neuroscience Peer Review Consortium
  481. The Neuronal Expression of MYC Causes a Neurodegenerative Phenotype in a Novel Transgenic Mouse
  482. The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells
  483. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α
  484. Is Alzheimers Disease a Myth? When is Disease a Disease?
  485. Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease
  486. Altered redox balance in disease: Can we change the new equilibria?
  487. Brain Composition: Age-Related Changes
  488. Alzheimer’s Disease: An Overview
  489. Treatment advances in Alzheimer’s disease based on the oxidative stress model
  490. The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival
  491. Oxidative Stress Associated Signal Transduction Cascades in Alzheimer Disease
  492. Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease
  493. Journal of Bioequivalence & Bioavailability
  494. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease
  495. Development of iron chelator–nanoparticle conjugates as potential therapeutic agents for Alzheimer disease
  496. Current Hypotheses and Research Milestones in Alzheimer's Disease
  497. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease
  498. Alzheimer Disease: Oxidative Stress and Compensatory Responses
  499. Neuronal Cytoskeleton Regulation and Neurodegeneration
  500. Are Amyloids Infectious?
  501. Cerebral and Cardiac Vascular Pathology in Alzheimer’s Disease
  502. How Biochemical Pathways for Disease May be Triggered by Early-Life Events
  503. Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress
  504. Oxidative Stress Signaling in Alzheimers Disease
  505. Neuroprotective effect of cocoa flavonids on in vitro oxidative stress
  506. Antioxidant Therapy in Alzheimers Disease: Theory and Practice
  507. Transgenic Mouse Models of Alzheimer's Disease
  508. Faculty of 1000 evaluation for Mitochondrial fragmentation in neurodegeneration.
  509. Alzheimer's Disease: Cerebrovascular Dysfunction, Oxidative stress, and Advanced Clinical Therapies
  510. Redox active iron accumulation in aceruloplasminemia
  511. Cellular Respiration and Tumor Suppressor Genes
  512. Faculty of 1000 evaluation for The amyloid cascade hypothesis.
  513. Faculty of 1000 evaluation for Prediction of aggregation-prone regions in structured proteins.
  514. Faculty of 1000 evaluation for Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease.
  515. Faculty of 1000 evaluation for Amyloid precursor protein expression is upregulated in adipocytes in obesity.
  516. Antigenantibody dissociation in Alzheimer disease: a novel approach to diagnosis
  517. Neuronal binucleation in Alzheimer disease hippocampus
  518. Phosphorylated Tau: Toxic, Protective, or None of the Above
  519. Upcoming Meetings Related to Alzheimer's Disease*
  520. Is Tau Aggregation Toxic or Protective?
  521. Is Tau Aggregation Toxic or Protective?
  522. Stem cell niches as clinical targets: the future of anti-ischemic therapy?
  523. Activation of MKK6, an upstream activator of p38, in Alzheimer's disease
  524. P4-171: Cerebral hypoperfusion-induced oxidative stress and mitochondrial failure as initiators of aging and Alzheimer's disease pathology
  525. P4-166: Overexpression of amyloid precursor protein causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
  526. P3-317: Failure in the control of cell cycle causes neurodegeneration
  527. P1-351: A novel approach to diagnosis: Antigen-antibody disassociation in Alzheimer's disease
  528. Nonestrogen-based hormonal therapies for Alzheimer’s disease
  529. Cerebrotendinous xanthomatosis: a critical update
  530. Three-Dimensional Tomographic Imaging and Characterization of Iron Compounds within Alzheimer's Plaque Core Material
  531. Alzheimer Disease Pathology As a Host Response
  532. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: Implication in the pathogenesis of Alzheimer’s disease
  533. Antibodies to Potato Virus Y Bind the Amyloid   Peptide: IMMUNOHISTOCHEMICAL AND NMR STUDIES
  534. Sublethal RNA Oxidation as a Mechanism for Neurodegenerative Disease
  535. Faculty of 1000 evaluation for N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
  536. Faculty of 1000 evaluation for Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.
  537. DOES THE OXIDATIVE STRESS AND CEREBRAL ATHEROSCLEROSIS INITIATE BRAIN HYPOPERFUSION AND THE DEVELOPMENT OF ALZHEIMER DISEASE?
  538. Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes
  539. Faculty of 1000 evaluation for Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers.
  540. Nucleic acid oxidation in Alzheimer disease
  541. Current approaches in the treatment of Alzheimer's disease
  542. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats
  543. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s disease
  544. The primary pathogenetic role of vascular hypoperfusion, mitochondria failure and oxidative stress in aging and Alzheimer disease
  545. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
  546. Physiological regulation of tau phosphorylation during hibernation
  547. Alzheimer Disease and the Role of Free Radicals in the Pathogenesis of the Disease
  548. Oxidative Stress and Neurotoxicity
  549. Menopause, Estrogen, and Gonadotropins in Alzheimer's Disease
  550. Leucine-Rich Repeat Kinase 2 Colocalizes with α-Synuclein in Parkinson’s Disease, but Not Tau-Containing Deposits in Tauopathies
  551. Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease
  552. A New Model of Oxidative Stress in Rat Pups
  553. Protein Misfolding in Alzheimer's Disease
  554. Neuronal Death and Survival Under Oxidative Stress in Alzheimer and Parkinson Diseases
  555. Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-β peptide
  556. Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia
  557. Insights into amyloid-β-induced mitochondrial dysfunction in Alzheimer disease
  558. Evidence for the Role of Luteinizing Hormone in Alzheimer Disease
  559. Oxidative RNA Damage and Neurodegeneration
  560. The role of novel chitin-like polysaccharides in Alzheimer disease
  561. Increased Autophagic Degradation of Mitochondria in Alzheimer Disease
  562. Oxidative stress activates a positive feedback between the γ- and β-secretase cleavages of the β-amyloid precursor protein
  563. Three Histidine Residues of Amyloid-β Peptide Control the Redox Activity of Copper and Iron
  564. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology
  565. Faculty of 1000 evaluation for Imaging of amyloid burden and distribution in cerebral amyloid angiopathy.
  566. The Contribution of Luteinizing Hormone to Alzheimer Disease Pathogenesis
  567. Oxidative Stress Is an Early Event in Hydrostatic Pressure–Induced Retinal Ganglion Cell Damage
  568. Lipoic Acid and N-acetyl Cysteine Decrease Mitochondrial-Related Oxidative Stress in Alzheimer Disease Patient Fibroblasts
  569. Nanoparticles for the Treatment of Alzheimer's Disease: Theoretical Rationale, Present Status and Future Perspectives
  570. Faculty of 1000 evaluation for Time resolved structure analysis of growing beta-amyloid fibers.
  571. Faculty of 1000 evaluation for Antioxidant capacity in postmortem brain tissues of Parkinson's and Alzheimer's diseases.
  572. Olfactory dysfunction in Parkinson's disease
  573. Causes of oxidative stress in Alzheimer disease
  574. Errata
  575. Autophagocytosis of Mitochondria Is Prominent in Alzheimer Disease
  576. Vascular oxidative stress in Alzheimer disease
  577. Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress
  578. c-Jun phosphorylation in Alzheimer disease
  579. PO13-357 THE PRIMARY PATHOGENETIC ROLE OF VASCULAR HYPOPERFUSION, AND OXIDATIVE STRESS IN ALZHEIMER DISEASE
  580. Iron: The Redox-active Center of Oxidative Stress in Alzheimer Disease
  581. Signal Transduction Cascades Associated with Oxidative Stress in Alzheimer's Disease
  582. Treating the Lesions, Not the Disease
  583. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?
  584. Lipoic acid and N-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients
  585. Mitochondrial autophagocytosis in Alzheimer disease
  586. Faculty of 1000 evaluation for Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry.
  587. Faculty of 1000 evaluation for Oxidative stress mediates tau-induced neurodegeneration in Drosophila.
  588. Increases in luteinizing hormone are associated with declines in cognitive performance
  589. Alzheimer disease, the two-hit hypothesis: An update
  590. Mitochondrial Autophagocytosis in Alzheimer Disease
  591. Indices of Metabolic Dysfunction and Oxidative Stress
  592. Sir Martin Roth – A Debt of Gratitude
  593. Prevention and Treatment of Alzheimer Disease and Aging: Antioxidants
  594. Increased Expression of the Remodeling- and Tumorigenic-Associated Factor Osteopontin in Pyramidal Neurons of the Alzheimers Disease Brain
  595. Amyloid-β in Alzheimer Disease: The Null versus the Alternate Hypotheses
  596. Role of Neu4L sialidase and its substrate ganglioside GD3 in neuronal apoptosis induced by catechol metabolites
  597. The Role of Oxidative Damage to Nucleic Acids in the Pathogenesis of Neurological Disease
  598. The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics
  599. The Pathology of Alzheimer Disease Elicits an In Vivo Immunological Response
  600. The Key Role of Oxidative Stress in Alzheimer's Disease
  601. Prospects for Antioxidant Therapy in Mild Cognitive Impairment and Alzheimer's Disease
  602. Gonadotropins: A cohesive gender-based etiology of Alzheimer disease
  603. Advanced Maillard Reaction End Products, Free Radicals, and Protein Oxidation in Alzheimer's Diseasea
  604. Malignant glioma progression and nitric oxide
  605. Aberrant localization of importin α1 in hippocampal neurons in Alzheimer disease
  606. LRRK2 protein is a component of lewy bodies
  607. Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells
  608. Nanoparticle iron chelators: A new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance
  609. Commentary on “Perspective on a pathogenesis and treatment of Alzheimer’s disease.” Therapeutic strategies for Alzheimer’s disease: The need for a new era of innovation
  610. Increased Expression of p130 in Alzheimer Disease
  611. Synaptic dysfunction and oxidative stress in Alzheimer's disease: Emerging mechanisms
  612. Foreword: Apoptotic Mechanisms in Neurodegenerative Diseases
  613. Apoptosis in Alzheimer Disease: A Mathematical Improbability
  614. Amyloid-β Vaccination: Testing the Amyloid Hypothesis?
  615. Solving the insoluble
  616. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease
  617. Synaptic dysfunction and oxidative stress in Alzheimer's disease: Emerging mechanisms
  618. Involvement of Oxidative Stress in Alzheimer Disease
  619. Emerging evidence for the neuroprotective role of α-synuclein
  620. Telomeres and telomerase in Alzheimer’s disease: Epiphenomena or a new focus for therapeutic strategy?
  621. P4-162
  622. P3-375
  623. P3-296
  624. P3-369
  625. P3-372
  626. P1-388
  627. P1-417
  628. Amyloid-β, BACE, and oxidative stress in Alzheimer's disease, a commentary on “The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression”
  629. Therapeutic options in Alzheimer’s disease
  630. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease
  631. Neuropathology in Alzheimer's Disease: Awaking from a Hundred-Year-Old Dream
  632. LC-MS display of the total modified amino acids in cataract lens proteins and in lens proteins glycated by ascorbic acid in vitro
  633. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic
  634. The Role of Oxidative Stress in the Pathophysiology of Cerebrovascular Lesions in Alzheimer's Disease
  635. Will Preventing Protein Aggregates Live Up to Its Promise as Prophylaxis Against Neurodegenerative Diseases?
  636. Luteinizing hormone modulates cognition and amyloid-β deposition in Alzheimer APP transgenic mice
  637. α-Synuclein facilitates the toxicity of oxidized catechol metabolites: Implications for selective neurodegeneration in Parkinson's disease
  638. Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy
  639. Presenilin mutation: A deadly first hit in Alzheimer disease
  640. Antioxidant protection and neurodegenerative disease: The role of amyloid-β and tau
  641. Amyloid Beta: The Alternate Hypothesis
  642. The Cell Cycle and Hormonal Fluxes in Alzheimer Disease: A Novel Therapeutic Target
  643. Arson: Tracking the Culprit in Alzheimer's Disease
  644. Brain and brawn
  645. The Estrogen Myth
  646. Targeting Gonadotropins: An Alternative Option for Alzheimer Disease Treatment
  647. Neurogenesis in Human Hippocampus: Implications for Alzheimer Disease Pathogenesis
  648. Neurodegenerative Diseases: Mechanisms and Therapies
  649. Heme Deficiency in Alzheimer’s Disease: A Possible Connection to Porphyria
  650. Ectopic expression of phospho-Smad2 in Alzheimer's disease: Uncoupling of the transforming growth factor-β pathway?
  651. Oxidative Damage to RNA in Neurodegenerative Diseases
  652. Compensatory responses induced by oxidative stress in Alzheimer disease
  653. The Fallacy of Amyloid and Cognition in Alzheimer???s Disease
  654. Therapeutic potential of oxidative stress reduction in Alzheimer's disease
  655. Oxidative Adaptation in Aging and Alzheimer’s Disease
  656. Temporal Primacy of Oxidative Stress in the Pathological Cascade of Alzheimer Disease
  657. Antioxidant Therapies in the Prevention and Treatment of Alzheimer Disease
  658. Amyloid- _ and _ in Alzheimer’s Disease
  659. Faculty of 1000 evaluation for The use of memantine in dementia with Lewy bodies.
  660. Faculty of 1000 evaluation for The most infectious prion protein particles.
  661. Faculty of 1000 evaluation for Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.
  662. The cell cycle in Alzheimer disease: A unique target for neuropharmacology
  663. Oxidative Stress: The Old Enemy in Alzheimers Disease Pathophysiology
  664. Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers
  665. Chitin-like Polysaccharides in Alzheimers Disease Brains
  666. Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease
  667. Nanoparticle and other metal chelation therapeutics in Alzheimer disease
  668. Alzheimer's disease: an intracellular movement disorder?
  669. Redox metals and oxidative abnormalities in human prion diseases
  670. Faculty of 1000 evaluation for Alpha-synuclein alters proteasome function, protein synthesis, and stationary phase viability.
  671. 4-Oxo-2-nonenal Is Both More Neurotoxic and More Protein Reactive than 4-Hydroxy-2-nonenal
  672. Faculty of 1000 evaluation for Anchorless prion protein results in infectious amyloid disease without clinical scrapie.
  673. The primary pathogenetic role of vascular contains vasoactive substances, hypoperfusion, mitochondria failure and oxidative stress in aging and Alzheimer disease
  674. Commentary: “Ceramide and cholesterol: Possible connections between normal aging of the brain and Alzheimer’s disease. Just hypotheses or molecular pathways to be identified?” By Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli
  675. Ferric Cycle Activity and Alzheimer Disease
  676. Oxidative Stress and Neurodegeneration
  677. P38 Activation Mediates Amyloid-β Cytotoxicity
  678. Estrogen Bows to a New Master: The Role of Gonadotropins in Alzheimer Pathogenesis
  679. Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease
  680. Role of Amyloid-β in Alzheimer's Disease
  681. The End of a Chilean Institute
  682. Carnosine: A Versatile Antioxidant and Antiglycating Agent
  683. Therapeutic Opportunities in Alzheimer Disease: One for all or all for One?
  684. Raffinee in the Treatment of Spinal Cord Injury: An Open-Labeled Clinical Trial
  685. Chronological primacy of oxidative stress in Alzheimer disease
  686. Faculty of 1000 evaluation for Mechanisms of 4-hydroxynonenal-induced neuronal microtubule dysfunction.
  687. Tau phosphorylation in Alzheimer's disease: pathogen or protector?
  688. Nuclear microscopy of diffuse plaques in the brains of transgenic mice
  689. Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron
  690. Ciprofloxacin Does Not Exert Nephrotoxicity in Rats
  691. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations
  692. Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease
  693. Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved
  694. Faculty of 1000 evaluation for The potential role of tau protein O-glycosylation in Alzheimer's disease.
  695. Faculty of 1000 evaluation for Oxygen causes cell death in the developing brain.
  696. Faculty of 1000 evaluation for Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology.
  697. Faculty of 1000 evaluation for Amyloid-beta binds Cu2+ in a mononuclear metal ion binding site.
  698. Faculty of 1000 evaluation for Interaction of Tau with Fe65 links tau to APP.
  699. Faculty of 1000 evaluation for Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation.
  700. beta-Site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways
  701. Alzheimer?s disease: the impact of age-related changes in reproductive hormones
  702. Tau modifiers as therapeutic targets for Alzheimer's disease
  703. Oxidative Imbalance in Alzheimer's Disease
  704. Oxidative damage and Alzheimer's disease: Are antioxidant therapies useful?
  705. Mitogen- and stress-activated protein kinase 1: Convergence of the ERK and p38 pathways in Alzheimer's disease
  706. MAPKs are differentially modulated in arctic ground squirrels during hibernation
  707. Introduction: Imaging in Alzheimer's disease
  708. Concealment of epitope by reduction and alkylation in prion protein
  709. Oxidative stress mechanisms and potential therapeutics in Alzheimer disease
  710. Neurofilament proteins in neurodegenerative diseases
  711. Therapeutic potential of oxidant mechanisms in Alzheimer’s disease
  712. Mitochondrial failures in Alzheimer's disease
  713. Staying Connected
  714. Faculty of 1000 evaluation for RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.
  715. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease
  716. Symposium
  717. Heme Catabolism and Heme Oxygenase in Neurodegenerative Disease
  718. Faculty of 1000 evaluation for Kinetic control of dimer structure formation in amyloid fibrillogenesis.
  719. Faculty of 1000 evaluation for Mild cognitive impairment as a diagnostic entity.
  720. Faculty of 1000 evaluation for Systemic catabolism of Alzheimer's Abeta40 and Abeta42.
  721. Faculty of 1000 evaluation for A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis.
  722. Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease
  723. Faculty of 1000 evaluation for Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains.
  724. Faculty of 1000 evaluation for Formation of amyloid fibers triggered by phosphatidylserine-containing membranes.
  725. Faculty of 1000 evaluation for Targeting prion amyloid deposits in vivo.
  726. Faculty of 1000 evaluation for Degradation of BACE by the ubiquitin-proteasome pathway.
  727. Beyond Estrogen: Targeting Gonadotropin Hormones in the Treatment of Alzheimers Disease
  728. Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease
  729. Accelerated α-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells
  730. S4-02-01 Alzheimer disease: the two hit hypothesis
  731. P4-250 Redox-active iron oxidizes ribosomal RNa in neurons vulnerable to Alzheimer's disease
  732. P4-242 Oxidative damage in ferritin-induced neurodegeneration
  733. P3-306 Differential expression of metabotrophic glutamate receptors (MGlurs) in Alzheimer disease
  734. P3-275 Phosphorylation dependent control of oxidative modification in Alzheimer disease
  735. P3-219 Acetylation: a novel posttranslational modification in Alzheimer disease
  736. P2-003 Cholesterol feeding enhances cerebral amyloid beta pathology in beagles
  737. P1-369 Modulation of cognition and amyloid load in the aged SWAβPP transgenic mouse by luprolide acetate, a GNRH agonist: targeting luteinizing hormone as a novel treatment for AD
  738. P1-286 Glycogen synthase kinase-3β activity is regulated by products of lipid peroxidation: relevance to Alzheimer disease
  739. P1-266 The critical role of the ERK pathway in the pathogenesis of Alzheimer's disease
  740. O3-04-07 Vascular and metabolic failure in Alzheimer disease
  741. O2-04-07 Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer disease
  742. Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease?
  743. Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells
  744. Neuroprotective properties of Bcl-w in Alzheimer disease
  745. In Situ Localization of Nonenzymatic Peroxidase-Like Activity of Tissue-Bound Transition Metals
  746. Homocysteine and Alzheimer's disease: a modifiable risk?
  747. Challenging the Amyloid Cascade Hypothesis: Senile Plaques and Amyloid-β as Protective Adaptations to Alzheimer Disease
  748. VASCULAR HYPOPERFUSION AND MITOCHONDRIA ABNORMALITY INDUCE OXIDATIVE STRESS THAT APPEARED TO BE A KEY FACTOR FOR THE DEVELOPMENT OF ALZHEIMER DISEASE
  749. Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer’s disease pathogenesis
  750. Assembly In Vitro of Tau Protein and its Implications in Alzheimers Disease
  751. Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice
  752. Perspectives on the Amyloid-β Cascade Hypothesis
  753. Oxidative stress signalling in Alzheimer's disease
  754. Oxidative Stress and Redox-Active Iron in Alzheimer's Disease
  755. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease
  756. Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer’s disease
  757. Luteinizing Hormone, a Reproductive Regulator That Modulates the Processing of Amyloid-β Precursor Protein and Amyloid-β Deposition
  758. Distribution, levels, and activation of MEK1 in Alzheimer's disease
  759. Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients
  760. Oxidative Stress Mechanisms and Potential Therapeutic Modalities in Alzheimer Disease
  761. Oxidative Stress in Alzheimer Disease: The Earliest Cytological and Biochemical Feature
  762. Nutritional Antioxidants, Vitamins, Cognition, and Neurodegenerative Disease
  763. Mechanisms Involved in Gender Differences in Alzheimer's Disease: The Role of Leuteinizing and Follicle Stimulating Hormones
  764. Editors' Summary
  765. Copper Mediates Dityrosine Cross-Linking of Alzheimer's Amyloid-β †
  766. Amyloid-β-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression
  767. Oxidative damage in the olfactory system in Alzheimer's disease
  768. Amyloids, Aggregates and Neuronal Inclusions: Good or Bad News for Neurons?
  769. La función del estrés oxidativo en la patogénesis de la enfermedad de Alzheimer
  770. Oxidative Stress and Neuronal Adaptation in Alzheimer Disease: The Role of SAPK Pathways
  771. Metal Homeostasis and Its Relation to Oxidative Stress in Alzheimer’s Disease
  772. Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply
  773. Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β
  774. Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice
  775. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
  776. Possible involvement of Wiskott–Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease
  777. Hydroxynonenal, toxic carbonyls, and Alzheimer disease
  778. Functional Implications of Antiestrogen Induction of Quinone Reductase: Inhibition of Estrogen-Induced Deoxyribonucleic Acid Damage
  779. Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway
  780. 4-Hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis
  781. Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants
  782. Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out?
  783. Oxidative stress and predominant Aβ42(43) deposition in myopathies with rimmed vacuoles
  784. Metal Binding and Oxidation of Amyloid-β within Isolated Senile Plaque Cores:  Raman Microscopic Evidence †
  785. JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease
  786. Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?
  787. Role of high mobility group protein-1 (HMG1) in amyloid-β homeostasis
  788. Signal Transduction in Alzheimer's Disease
  789. Hypoperfusion, Mitochondria Failure, Oxidative Stress, and Alzheimer Disease
  790. Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells
  791. Role of the antioxidant ascorbate in hibernation and warming from hibernation
  792. Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response
  793. Induction of Heme Oxygenase-1 mRNA and Protein in Neocortex and Cerebral Vessels in Alzheimer's Disease
  794. Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress
  795. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies
  796. Atherosclerotic Lesions and Mitochondria DNA Deletions in Brain Microvessels as a Central Target for the Development of Human AD and AD-Like Pathology in Aged Transgenic Mice
  797. Amyloid-β and τ serve antioxidant functions in the aging and Alzheimer brain
  798. Amyloid-β: a (life) preserver for the brain
  799. Amyloid-?: A vascular sealant that protects against hemorrhage?
  800. Role of mitochondrial dysfunction in Alzheimer's disease
  801. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology
  802. Mitochondrial Abnormalities and Oxidative Imbalance in Neurodegenerative Disease
  803. Book Review: Is Alzheimer’s Disease a Mitochondrial Disorder?
  804. Lipid peroxidation in aging brain and Alzheimer’s disease1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers ma...
  805. Therapeutic Potential in Alzheimer Disease
  806. Oxidative Stress Increases Expression and Activity of BACE in NT2 Neurons
  807. Ill-fated amyloid-? vaccine
  808. Senile plaque composition and posttranslational modification of amyloid-β peptide and associated proteins
  809. Possible mechanisms of APP-mediated oxidative stress in Alzheimer’s disease1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full...
  810. Metals and oxidative homeostasis in Alzheimer's disease
  811. Cholesterol, oxidative stress, and Alzheimer’s disease: expanding the horizons of pathogenesis1 1This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found o...
  812. The state versus amyloid-β: the trial of the most wanted criminal in Alzheimer disease
  813. Causes and consequences of oxidative stress in Alzheimer’s disease 1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full lis...
  814. The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer’s and Parkinson’s diseases1,2 11Guest Editors: Mark A. Smith and George Perry 22This article is part of a series of reviews on “Causes and Consequences of Oxid...
  815. Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a s...
  816. Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer’s disease1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is a part of a series of reviews on “Causes and Consequences of Oxidative Stre...
  817. Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease1,2 1This article is part of a series of reviews on “Causes and Consequences of Oxidative S...
  818. Decreased activity of the antioxidant heme oxygenase enzyme: implications in ischemia and in Alzheimer’s disease1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Str...
  819. Apolipoprotein E isoform mediated regulation of nitric oxide release1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list o...
  820. Dangers of the amyloid-β vaccination
  821. Amyloid-β, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?
  822. Oxidative Damage to Nucleic Acids in Human Prion Disease
  823. Microglial activation and amyloid-β clearance induced by exogenous heat-shock proteins
  824. The “Down's” Side of Mitochondria
  825. Systemic Increase of Oxidative Nucleic Acid Damage in Parkinson's Disease and Multiple System Atrophy
  826. Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity
  827. Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans
  828. Alzheimer Disease and Oxidative Stress
  829. The Role of Iron and Copper in the Aetiology of Neurodegenerative Disorders
  830. Signal Transduction in Alzheimer’s Disease
  831. Role of Heme Catabolism in Neurodegenerative Diseases
  832. Neuronal Survival and Death in Alzheimer Disease
  833. Iron: A Pathological Mediator of Alzheimer Disease?
  834. Involvement of maillard reactions in Alzheimer disease
  835. Differential Regulation of Glutamate Receptors in Alzheimer’s Disease
  836. In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease
  837. High Molecular Weight Neurofilament Proteins Are Physiological Substrates of Adduction by the Lipid Peroxidation Product Hydroxynonenal
  838. Atherosclerotic Lesions Are Associated with Increased Immunoreactivity for Inducible Nitric Oxide Synthase and Endothelin-1 in Thoracic Aortic Intimal Cells of Hyperlipidemic Watanabe Rabbits
  839. Chemistry and Biochemistry of Oxidative Stress in Neurodegenerative Disease
  840. Effect of the herbicide 4-CPA on human erythrocyte antioxidant enzymesin vitro
  841. Abortive apoptosis in Alzheimer's disease
  842. Forward
  843. Erythrocyte, plasma, and serum antioxidant activities in untreated toxic multinodular goiter patients
  844. Redox-active iron mediates amyloid-β toxicity
  845. Hibernation, a Model of Neuroprotection
  846. Do Neurons Have a Choice in Death?
  847. Protein Disulfide Isomerase in Alzheimer Disease
  848. Metabolic, Metallic, and Mitotic Sources of Oxidative Stress in Alzheimer Disease
  849. Sequestration of iron by Lewy bodies in Parkinson's disease
  850. Oxidative damage in Alzheimer’s disease: the metabolic dimension
  851. Oxidative stress in Alzheimer’s disease
  852. Activation of NADPH Oxidase in Alzheimer's Disease Brains
  853. Competitive regulation of aβredox activity by copper and zinc: Parallels in the pathogenetic mechanisms of Alzheimer's disease and familial amyotrophic lateral sclerosis
  854. Alzheimer's plaques re-created in a test tube: Further insights into the mechanism of amyloid plaque formation
  855. Activation of P38 kinase links π phosphorylation, oxidative stress and cell cycle-related events in Alzheimer disease
  856. Mitochondrial abnormalities in Alzheimer disease
  857. Increased oxidative stress involving olfactory neurons in Alzheimer disease
  858. Human amyloid-derived aßcontains tyrosine cross-linked oligomers
  859. Evidence for a Novel Heme-Binding Protein, HasAh, in Alzheimer Disease
  860. How important is oxidative damage? Lessons from Alzheimer’s disease
  861. Amyloid-β junkies
  862. Overexpression of Heme Oxygenase in Neuronal Cells, the Possible Interaction with Tau
  863. Histochemical and Immunocytochemical Approaches to the Study of Oxidative Stress
  864. Methods in Molecular Medicine, Vol. 32 Alzheimer's Disease: Methods and Protocols
  865. Neurodegeneration Methods and Protocols Jean Harry Hugh A. Tilson
  866. Neuronal RNA Oxidation in Alzheimer's Disease and Down's Syndrome
  867. Diet and Oxidative Stress: A Novel Synthesis of Epidemiological Data on Alzheimer's Disease*
  868. Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?
  869. INDUCTION OF NAPH CYTOCHROME P450 REDUCTASE BY AMYLOID β PROTEIN
  870. The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction
  871. Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease
  872. Hypertension in Dialysis Patients
  873. RNA Oxidation in Alzheimer and Parkinson Diseases
  874. [10] In situ methods for detection and localization of markers of oxidative stress: Application in neurodegenerative disorders
  875. What are the facts and artifacts of the pathogenensis and etiology of Alzheimer disease?
  876. A suicide note from Alzheimer disease neurons?
  877. Cerebrovascular muscle atrophy is a feature of Alzheimer's disease
  878. Astrocytes Regulate Microglial Phagocytosis of Senile Plaque Cores of Alzheimer's Disease
  879. Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease
  880. The Role of Oxidative Stress in the Pathological Sequelae of Alzheimer Disease
  881. Neuronal Oxidative Stress is a Common Feature of Alzheimer’s and Parkinson’s Diseases
  882. ADVANCED GLYCATION AND LIPID MODIFICATION OF ROSENTHAL FIBERS IN ALEXANDERʼS DISEASE
  883. Letter to the Editor
  884. Early contribution of oxidative glycation in Alzheimer disease
  885. Oxidative posttranslational modifications in Alzheimer disease
  886. APP transgenesis: Approaches toward the development of animal models for Alzheimer disease neuropathology
  887. Trypsin interaction with the senile plaques of Alzheimer disease is mediated by β-protein precursor
  888. Protein Modifications and Interactions in Alzheimer’s Disease
  889. Glial Cell Extracellular Matrix in Alzheimer's Disease
  890. Free radical damage, iron, and Alzheimer's disease
  891. Evidence for oxidative stress in Pick disease and corticobasal degeneration
  892. Amyloidosis, advanced glycation end products and Alzheimer disease
  893. Reply
  894. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide
  895. Characterization of the association of phospholipase C-δ with Alzheimer neurofibrillary tangles
  896. Alzheimer disease: An imbalance of proteolytic regulation?
  897. β-Amyloid of Alzheimer's Disease Induces Reactive Gliosis That Inhibits Axonal Outgrowth
  898. Barrier properties of testis microvessels.
  899. The Amyloid Precursor Protein in Ischemic Brain Injury and Chronic Hypoperfusiona
  900. Aberrant Phosphoinositide Metabolism in Alzheimer's Diseasea
  901. α1-Trypsin Immunoreactivity in Alzheimer Disease
  902. Chondroitin Sulfate Proteoglycans Are Associated with the Lesions of Alzheimer's Disease
  903. Accumulation of the β amyloid precursor protein at sites of ischemic injury in rat brain
  904. Corrigendum
  905. Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases
  906. The Neuronal Cytoskeleton
  907. α1-Antitrypsin and α1-antichymotrypsin are in the lesions of Alzheimerʼs disease
  908. Dementia with argyrophilic grains
  909. Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease.
  910. Tropomyosin distinguishes Lewy bodies of Parkinson disease from other neurofibrillary pathology
  911. Role of cytokeratin intermediate filaments in transhepatic transport and canalicular secretion
  912. Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease
  913. Immunochemical Properties of Ubiquitin Conjugates in the Paired Helical Filaments of Alzheimer Disease
  914. Phosphorylation of Neurofilaments Is Altered in Amyotrophic Lateral Sclerosis
  915. AMYLOID PRECURSOR PROTEIN IN SENILE PLAQUES OF ALZHEIMER DISEASE
  916. Alterations in the Neuronal Cytoskeleton in Alzheimer Disease
  917. Hirano bodies contain tau protein
  918. Ubiquitin in Alzheimer and other Neurodegenerative Diseases
  919. Microfilament Involvement in Hirano Body Formation
  920. Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus
  921. Alteration of the Neurofilament-Microtubule Network in Alzheimer Disease and Other Neurodegenerative Disorders
  922. Fertilization stimulates lipid peroxidation in the sea urchin egg
  923. Interaction of Calcium-Calmodulin in Microtubule Assembly in Vitro
  924. Ca2+-stimulated production of H2O2 from naphthoquinone oxidation in Arbacia eggs
  925. Faculty of 1000 evaluation for Heme Binding Induces Dimerization and Nitration of Truncated β-Amyloid Peptide Aβ16 Under Oxidative Stress.
  926. Two Hits and You’re Out? A Novel Mechanistic Hypothesis of Alzheimer Disease
  927. Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases
  928. The Changing landscape of Alzheimer’s disease: From Insoluble to Soluble and from Pathogen to Protector
  929. Neurogenesis in Alzheimer’s Disease
  930. Mechanisms of DNA Damage and Repair in Alzheimer Disease
  931. Cell Cycle Activation and the Amyloid-β Protein in Alzheimer’s Disease
  932. Neuroinflammatory Environments Promote Amyloid-β Deposition and Posttranslational Modification
  933. Apoptotic and Oxidative Indicators in Alzheimer's Disease
  934. Phosphorylation, Microtubule Binding and Aggregation of Tau Protein in Alzheimer's Disease
  935. Oxidative Damage and Antioxidant Responses in Alzheimer's Disease
  936. Neuroinflammatory Responses in the Alzheimer's Disease Brain Promote the Oxidative Post-translational Modification of Amyloid Deposits
  937. Involvement of gonadotropins in cognitive function: implications for Alzheimer's disease
  938. Faculty of 1000 evaluation for Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis.
  939. Faculty of 1000 evaluation for The biphasic relationship between regional brain senile plaque and neurofibrillary tangle distributions: modification by age, sex, and APOE polymorphism.
  940. Faculty of 1000 evaluation for The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.
  941. Faculty of 1000 evaluation for Testing the amyloid toxicity hypothesis of Alzheimer's disease in transgenic Caenorhabditis elegans model.
  942. Faculty of 1000 evaluation for Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds.
  943. Faculty of 1000 evaluation for Reduction of brain lipid peroxidation by CSF drainage in Alzheimer's disease patients.
  944. Faculty of 1000 evaluation for Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro.
  945. Faculty of 1000 evaluation for Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death.
  946. Faculty of 1000 evaluation for Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins.
  947. Faculty of 1000 evaluation for Physiological roles of amyloid-beta and implications for its removal in Alzheimer's disease.
  948. Faculty of 1000 evaluation for Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease.
  949. Faculty of 1000 evaluation for Midlife coffee and tea drinking and the risk of late-life dementia: a population-based CAIDE study.
  950. Faculty of 1000 evaluation for Metal ions differentially influence the aggregation and deposition of Alzheimer's beta-amyloid on a solid template.
  951. Faculty of 1000 evaluation for Low uric acid levels in serum of patients with ALS: further evidence for oxidative stress?
  952. Faculty of 1000 evaluation for Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage.
  953. Faculty of 1000 evaluation for Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.
  954. Faculty of 1000 evaluation for Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein.
  955. Faculty of 1000 evaluation for Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene.
  956. Faculty of 1000 evaluation for Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease.
  957. Faculty of 1000 evaluation for How changes in the sequence of the peptide CLPFFD-NH2 can modify the conjugation and stability of gold nanoparticles and their affinity for beta-amyloid fibrils.
  958. Faculty of 1000 evaluation for Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease.
  959. Faculty of 1000 evaluation for Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.
  960. Faculty of 1000 evaluation for Earliest stages of tau conformational changes are related to the appearance of a sequence of specific phospho-dependent tau epitopes in Alzheimer's disease.
  961. Faculty of 1000 evaluation for Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease?
  962. Faculty of 1000 evaluation for Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1.
  963. Faculty of 1000 evaluation for Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer's disease.
  964. Faculty of 1000 evaluation for Demonstration of a role for alpha-synuclein as a functional microtubule-associated protein.
  965. Faculty of 1000 evaluation for Deficiency of the copper chaperone for superoxide dismutase increases amyloid-β production.
  966. Faculty of 1000 evaluation for Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes.
  967. Faculty of 1000 evaluation for Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS.
  968. Faculty of 1000 evaluation for Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex.
  969. Faculty of 1000 evaluation for Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease.
  970. Faculty of 1000 evaluation for Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins.
  971. Faculty of 1000 evaluation for Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis.
  972. Faculty of 1000 evaluation for Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria.
  973. Faculty of 1000 evaluation for Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-type Ca2+ channels.
  974. Faculty of 1000 evaluation for ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration.
  975. Faculty of 1000 evaluation for alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons.
  976. Faculty of 1000 evaluation for Alpha-synuclein has structural and functional similarities to small heat shock proteins.
  977. Faculty of 1000 evaluation for Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.
  978. Faculty of 1000 evaluation for Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome.
  979. Faculty of 1000 evaluation for Aberrant neuronal and mitochondrial proteins in hippocampus of transgenic mice overexpressing human Cu/Zn superoxide dismutase 1.
  980. Faculty of 1000 evaluation for A new function of microtubule-associated protein tau: involvement in chromosome stability.
  981. Faculty of 1000 evaluation for A copper-binding site in the cytoplasmic domain of BACE1 identifies a possible link to metal homoeostasis and oxidative stress in Alzheimer's disease.
  982. Alternative approaches to Alzheimer's Disease