All Stories

  1. Modulation of Bromo- and Extra-Terminal Domain (BET) Proteins Exerts Neuroprotective Effects in Cell Culture Models of Parkinson’s Disease

    Article • Biomedicines, January 2026, MDPI AG

    Dr. Sandra Moreno

  2. p75NTR modulation by LM11A-31 counteracts oxidative stress and cholesterol dysmetabolism in a rotenone-induced cell model of Parkinson’s disease

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Dr. Sandra Moreno

  3. Nasal tau immunotherapy clears intracellular tau pathology and improves cognitive functions in aged tauopathy mice

    Article • Science Translational Medicine, July 2024, American Association for the Advancement of Science

    Dr. Sandra Moreno

  4. Trimetazidine Improves Mitochondrial Dysfunction in SOD1G93A Cellular Models of Amyotrophic Lateral Sclerosis through Autophagy Activation

    Article • International Journal of Molecular Sciences, March 2024, MDPI AG

    Dr. Sandra Moreno

  5. Caspase-dependent apoptosis in Riboflavin Transporter Deficiency iPSCs and derived motor neurons

    Article • Cell Death Discovery, January 2024, Springer Science + Business Media

    Dr. Sandra Moreno

  6. Vitamin B12 Deficiency and the Nervous System: Beyond Metabolic Decompensation—Comparing Biological Models and Gaining New Insights into Molecular and Cellular Mechanisms

    Article • International Journal of Molecular Sciences, January 2024, MDPI AG

    Dr. Sandra Moreno

  7. Caspase-dependent apoptosis in Riboflavin Transporter Deficiency iPSCs and derived motor neurons

    Article • June 2023, Springer Science + Business Media

    Dr. Sandra Moreno

  8. Bromodomain and Extra-Terminal Proteins in Brain Physiology and Pathology: BET-ing on Epigenetic Regulation

    Article • Biomedicines, March 2023, MDPI AG

    Dr. Sandra Moreno

  9. TERT Extra-Telomeric Roles: Antioxidant Activity and Mitochondrial Protection

    Article • International Journal of Molecular Sciences, February 2023, MDPI AG

    Dr. Sandra Moreno

  10. Resveratrol Analogs and Prodrugs Differently Affect the Survival of Breast Cancer Cells Impairing Estrogen/Estrogen Receptor α/Neuroglobin Pathway

    Article • International Journal of Molecular Sciences, January 2023, MDPI AG

    Dr. Sandra Moreno

  11. New Insights into the Neurodegeneration Mechanisms Underlying Riboflavin Transporter Deficiency (RTD): Involvement of Energy Dysmetabolism and Cytoskeletal Derangement

    Article • Biomedicines, June 2022, MDPI AG

    Dr. Sandra Moreno

  12. Dissecting the Role of PCDH19 in Clustering Epilepsy by Exploiting Patient-Specific Models of Neurogenesis

    Article • Journal of Clinical Medicine, June 2021, MDPI AG

    Dr. Sandra Moreno

  13. Altered cytoskeletal arrangement in induced pluripotent stem cells and motor neurons from patients with riboflavin transporter deficiency

    Article • Disease Models & Mechanisms, February 2021, The Company of Biologists

    Dr. Sandra Moreno

  14. Mitochondrial Abnormalities in Induced Pluripotent Stem Cells-Derived Motor Neurons from Patients with Riboflavin Transporter Deficiency

    Article • Antioxidants, December 2020, MDPI AG

    Dr. Sandra Moreno

  15. Mitochondrial Abnormalities in iPSC-Derived Motor Neurons From Patients With Riboflavin Transporter Deficiency

    Article • November 2020, MDPI AG

    Dr. Sandra Moreno

  16. Antioxidant Amelioration of Riboflavin Transporter Deficiency in Motoneurons Derived from Patient-Specific Induced Pluripotent Stem Cells

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Dr. Sandra Moreno

  17. Mitochondrial and Peroxisomal Alterations Contribute to Energy Dysmetabolism in Riboflavin Transporter Deficiency

    Article • Oxidative Medicine and Cellular Longevity, August 2020, Wiley

    Dr. Sandra Moreno

  18. Aged induced pluripotent stem cell (iPSCs) as a new cellular model for studying premature aging

    Article • Aging, May 2017, Impact Journals, LLC

    Dr. Sandra Moreno

  19. Ocular Nerve Growth Factor Administration Modulates Brain-derived Neurotrophic Factor Signaling in Prefrontal Cortex of Healthy and Diabetic Rats

    Article • CNS Neuroscience & Therapeutics, January 2017, Wiley

    Dr. Sandra Moreno

  20. Roles of PPAR transcription factors in the energetic metabolic switch occurring during adult neurogenesis

    Article • Cell Cycle, November 2016, Taylor & Francis

    Professor Rodolfo Ippoliti, Dr. Sandra Moreno

  21. Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

    Article • Cell Reports, May 2016, Elsevier

    Dr ir Wilfred van IJcken, Dr. Sandra Moreno

  22. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang, Professor George Perry, Professor Godefridus J Peters, Shuo-Chien Ling, Professor Jiwu Wei, Deepak Shukla, Dave Bridges

  23. Nerve growth factor and autophagy: effect of nasal anti-NGF-antibodies administration on Ambra1 and Beclin-1 expression in rat brain

    Article • Growth Factors, September 2015, Taylor & Francis

    Dr. Sandra Moreno

  24. neuroprotective properties of peroxisomal proliferators

    Article • Neural Regeneration Research, January 2015, Medknow

    Dr. Sandra Moreno

  25. Oxidative Stress during the Progression ofβ-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer’s Disease

    Article • Oxidative Medicine and Cellular Longevity, January 2015, Hindawi Publishing Corporation

    Dr. Sandra Moreno

  26. Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons

    Article • Cell Death and Disease, November 2014, Springer Science + Business Media

    Dr. Sandra Moreno

  27. Cocoa protective effects against abnormal fat storage and oxidative stress induced by a high-fat diet involve PPARα signalling activation

    Article • Food & Function, August 2014, Royal Society of Chemistry

    Dr. Sandra Moreno

  28. lipids in neuroprotection

    Article • Current Medicinal Chemistry, July 2014, Bentham Science Publishers

    Dr. Sandra Moreno

  29. Involvement of peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in BDNF signaling during aging and in Alzheimer disease: Possible role of 4-hydroxynonenal (4-HNE)

    Article • Cell Cycle, March 2014, Taylor & Francis

    Professor Rodolfo Ippoliti, Dr. Sandra Moreno

  30. Expression of Ambra1 in mouse brain during physiological and Alzheimer type aging

    Article • Neurobiology of Aging, January 2014, Elsevier

    Dr. Sandra Moreno

  31. Simvastatin Treatment Highlights a New Role for the Isoprenoid/Cholesterol Biosynthetic Pathway in the Modulation of Emotional Reactivity and Cognitive Performance in Rats

    Article • Neuropsychopharmacology, October 2013, Springer Science + Business Media

    Dr. Sandra Moreno

  32. Radiation response of chemically derived mitochondrial DNA-deficient AG01522 human primary fibroblasts

    Article • Mutation Research/Genetic Toxicology and Environmental Mutagenesis, August 2013, Elsevier

    Dr. Sandra Moreno

  33. A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury

    Article • PLOS One, June 2013, PLOS

    Dr. Sandra Moreno

  34. Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer’s disease

    Article • Molecular Neurodegeneration, January 2013, Springer Science + Business Media

    Dr. Sandra Moreno

  35. 3-hydroxy 3-methylglutaryl coenzyme a reductase inhibition impairs muscle regeneration

    Article • Journal of Cellular Biochemistry, April 2012, Wiley

    Dr. Sandra Moreno

  36. Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins

    Article • Cell Death and Differentiation, February 2012, Springer Science + Business Media

    Dr. Sandra Moreno

  37. Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage

    Article • Autophagy, February 2012, Taylor & Francis

    Dr. Sandra Moreno

  38. Suzuki-Miyaura cross-coupling of arenediazonium salts catalyzed by alginate/gellan-stabilized palladium nanoparticles under aerobic conditions in water

    Article • Green Chemistry, January 2012, Royal Society of Chemistry

    Dr. Sandra Moreno

  39. Effects of myosin heavy chain (MHC) plasticity induced by HMGCoA-reductase inhibition on skeletal muscle functions

    Article • The FASEB Journal, July 2011, Federation of American Societies For Experimental Biology (FASEB)

    Dr. Sandra Moreno

  40. Perturbation of Polyamine Catabolism Can Strongly Affect Root Development and Xylem Differentiation

    Article • PLANT PHYSIOLOGY, July 2011, American Society of Plant Biologists (ASPB)

    Dr. Sandra Moreno

  41. Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

    Article • Nature Neuroscience, December 2010, Springer Science + Business Media

    Dr. Sandra Moreno

  42. Characterization of gene expression induced by RTN-1C in human neuroblastoma cells and in mouse brain

    Article • Neurobiology of Disease, December 2010, Elsevier

    Dr. Sandra Moreno

  43. Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity

    Article • Human Molecular Genetics, September 2010, Oxford University Press (OUP)

    Dr. Sandra Moreno

  44. Early Biochemical and Morphological Modifications in the Brain of a Transgenic Mouse Model of Alzheimer's Disease: A Role for Peroxisomes

    Article • Journal of Alzheimer’s Disease, November 2009, IOS Press

    Dr. Sandra Moreno

  45. Inflammatory cytokines increase mitochondrial damage in motoneuronal cells expressing mutant SOD1

    Article • Neurobiology of Disease, December 2008, Elsevier

    Dr. Sandra Moreno

  46. Role of ER  palmitoylation in the inhibition of human colon cancer cell proliferation

    Article • Endocrine Related Cancer, March 2007, Bioscientifica

    Dr. Sandra Moreno

  47. Electrostatic Association of Glutathione Transferase to the Nuclear Membrane

    Article • Journal of Biological Chemistry, December 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Sandra Moreno

  48. Apoptosome impairment during development results in activation of an autophagy program in cerebral cortex

    Article • APOPTOSIS, June 2006, Springer Science + Business Media

    Dr. Sandra Moreno

  49. Mitochondrial type I nitric oxide synthase physically interacts with cytochrome c oxidase

    Article • Neuroscience Letters, August 2005, Elsevier

    Full Professor of Biochemistry Fabio Polticelli, Dr. Sandra Moreno

  50. Peroxisome Proliferator-Activated Receptors (PPARs) and related transcription factors in differentiating astrocyte cultures

    Article • Neuroscience, January 2005, Elsevier

    Dr. Sandra Moreno

  51. Cellular re-distribution of flavin-containing polyamine oxidase in differentiating root and mesocotyl of Zea mays L. seedlings

    Article • Planta, December 2004, Springer Science + Business Media

    Dr. Sandra Moreno

  52. Immunolocalization of peroxisome proliferator-activated receptors and retinoid x receptors in the adult rat CNS

    Article • Neuroscience, January 2004, Elsevier

    Dr. Sandra Moreno

  53. Polyamine Oxidase, a Hydrogen Peroxide-Producing Enzyme, Is Up-Regulated by Light and Down-Regulated by Auxin in the Outer Tissues of the Maize Mesocotyl

    Article • PLANT PHYSIOLOGY, February 2003, American Society of Plant Biologists (ASPB)

    Dr. Sandra Moreno

  54. ‘Tissue’ transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease

    Article • Cell Death and Differentiation, August 2002, Springer Science + Business Media

    Dr. Sandra Moreno

  55. Apaf1 reduced expression levels generate a mutant phenotype in adult brain and skeleton

    Article • Cell Death and Differentiation, February 2002, Springer Science + Business Media

    Dr. Sandra Moreno

  56. Early Alterations in Gene Expression and Cell Morphology in a Mouse Model of Huntington's Disease

    Article • Journal of Neurochemistry, January 2002, Wiley

    Dr. Sandra Moreno

  57. Article • Journal of Neurocytology, January 2001, Springer Science + Business Media

    Dr. Sandra Moreno

  58. Article • Journal of Neurocytology, January 1999, Springer Science + Business Media

    Dr. Sandra Moreno

  59. Interleukin-1-producing plasma cells in close contact with hepatocytes in patients with chronic active hepatitis

    Article • Journal of Hepatology, July 1997, Elsevier

    Dr. Sandra Moreno

  60. Morphometric analysis of liver and kidney peroxisomes in lactating rats and their pups after treatment with the peroxisomal proliferator di-(2-ethylexyl)phthalate

    Article • Biology of the Cell, January 1995, Wiley

    Dr. Sandra Moreno

  61. Unusual neurofilament composition in cerebellar unipolar brush neurons

    Article • Journal of Neurocytology, December 1993, Springer Science + Business Media

    Dr. Sandra Moreno

  62. Purification of peroxisomal fraction from rat brain

    Article • Neurochemistry International, September 1993, Elsevier

    Dr. Sandra Moreno