All Stories

  1. Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

    Article • Autophagy, April 2019, Taylor & Francis

    Professor Luca Scorrano

  2. scorrano

    Article • Annual Review of Physiology, February 2016, Annual Reviews

    Professor Luca Scorrano, Dr Lena Pernas

  3. The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

    Article • Cell Metabolism, June 2015, Elsevier

    Professor Luca Scorrano

  4. Opa1 Overexpression Ameliorates the Phenotype of Two Mitochondrial Disease Mouse Models

    Article • Cell Metabolism, June 2015, Elsevier

    Professor Luca Scorrano

  5. Extracellular Regulated Kinase Phosphorylates Mitofusin 1 to Control Mitochondrial Morphology and Apoptosis

    Article • Molecular Cell, April 2015, Elsevier

    Professor Luca Scorrano

  6. Mitochondria: from cell death executioners to regulators of cell differentiation

    Article • Trends in Cell Biology, December 2014, Elsevier

    Professor Luca Scorrano

  7. At the right distance: ER-mitochondria juxtaposition in cell life and death

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 2014, Elsevier

    Professor Luca Scorrano

  8. Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion

    Article • The Journal of Cell Biology, January 2014, Rockefeller University Press

    Professor Luca Scorrano

  9. Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

    Article • Cell, September 2013, Elsevier

    Professor Luca Scorrano

  10. Keeping mitochondria in shape: a matter of life and death

    Article • European Journal of Clinical Investigation, July 2013, Wiley

    Professor Luca Scorrano

  11. D. melanogaster, mitochondria and neurodegeneration: small model organism, big discoveries

    Article • Molecular and Cellular Neuroscience, July 2013, Elsevier

    Professor Luca Scorrano

  12. OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange

    Article • The EMBO Journal, May 2013, Wiley

    Professor Luca Scorrano

  13. Close encounter: mitochondria, endoplasmic reticulum and Alzheimer's disease

    Article • The EMBO Journal, October 2012, Wiley

    Professor Luca Scorrano

  14. Shaping the role of mitochondria in the pathogenesis of Huntington's disease

    Article • The EMBO Journal, March 2012, Wiley

    Professor Luca Scorrano

  15. Phagocytosis: Coupling of Mitochondrial Uncoupling and Engulfment

    Article • Current Biology, October 2011, Elsevier

    Professor Luca Scorrano

  16. Tonight, the same old, deadly programme: BH3-only proteins, mitochondria and yeast

    Article • The EMBO Journal, July 2011, Wiley

    Professor Luca Scorrano

  17. During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

    Article • Nature, April 2011, Nature

    Professor Luca Scorrano

  18. Traveling Bax and Forth from Mitochondria to Control Apoptosis

    Article • Cell, April 2011, Elsevier

    Professor Luca Scorrano

  19. Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli

    Article • EMBO Molecular Medicine, November 2010, EMBO

    Professor Luca Scorrano

  20. Trichoplein/mitostatin regulates endoplasmic reticulum–mitochondria juxtaposition

    Article • EMBO Reports, October 2010, EMBO

    Professor Luca Scorrano

  21. An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship

    Article • The EMBO Journal, August 2010, Wiley

    Professor Luca Scorrano

  22. A BID on mitochondria with MTCH2

    Article • Cell Research, July 2010, Nature

    Professor Luca Scorrano

  23. OPA1 and Its Clinical Implications

    Article • December 2009, Wiley

    Professor Luca Scorrano

  24. When separation means death: killing through the mitochondria, but starting from the endoplasmic reticulum

    Article • The EMBO Journal, June 2009, Wiley

    Professor Luca Scorrano

  25. The Mitochondrial Pathway: Focus on Shape Changes

    Article • January 2009, Springer Science + Business Media

    Professor Luca Scorrano

  26. Mitofusin 2 tethers endoplasmic reticulum to mitochondria

    Article • Nature, December 2008, Nature

    Professor Luca Scorrano

  27. Caspase-8 goes cardiolipin: a new platform to provide mitochondria with microdomains of apoptotic signals?: Figure 1.

    Article • The Journal of Cell Biology, November 2008, Rockefeller University Press

    Professor Luca Scorrano

  28. Multiple Functions of Mitochondria-Shaping Proteins

    Article • May 2008, Wiley

    Professor Luca Scorrano

  29. Mitofusin 2: A Mitochondria-Shaping Protein with Signaling Roles Beyond Fusion

    Article • Antioxidants & Redox Signaling, March 2008, Mary Ann Liebert Inc

    Professor Luca Scorrano

  30. Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts

    Article • Nature Protocols, February 2007, Nature

    Professor Luca Scorrano

  31. Measuring Mitochondrial Shape Changes and Their Consequences on Mitochondrial Involvement During Apoptosis

    Article • January 2007, Springer Science + Business Media

    Professor Luca Scorrano

  32. The many shapes of mitochondrial death

    Article • Oncogene, August 2006, Nature

    Professor Luca Scorrano

  33. (De)constructing Mitochondria: What For?

    Article • Physiology, August 2006, American Physiological Society

    Professor Luca Scorrano

  34. Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling

    Article • Cell, July 2006, Elsevier

    Professor Luca Scorrano

  35. OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

    Article • Cell, July 2006, Elsevier

    Professor Luca Scorrano

  36. Proteins That Fuse and Fragment Mitochondria in Apoptosis: Con-Fissing a Deadly Con-Fusion?

    Article • Journal of Bioenergetics and Biomembranes, June 2005, Springer Science + Business Media

    Professor Luca Scorrano

  37. Interactions of Chloromethyltetramethylrosamine (Mitotracker Orangetm) with Isolated Mitochondria and Intact Cells

    Article • Annals of the New York Academy of Sciences, November 1999, Wiley

    Professor Luca Scorrano