All Stories

  1. Targeting selective autophagy by AUTAC degraders

    Article • Autophagy, January 2020, Taylor & Francis

    Prof Hirokazu Arimoto

  2. AUTACs: Cargo-Specific Degraders Using Selective Autophagy

    Article • Molecular Cell, December 2019, Elsevier

    Prof Hirokazu Arimoto

  3. Facile fluorescent imaging of bacterial cell wall reveals the mode of action of antibiotics

    Article • Scientific Reports, April 2017, Nature

    Prof Hirokazu Arimoto

  4. Novel blood–brain barrier-permeable spin probe for in vivo electron paramagnetic resonance imaging

    Article • Bioorganic & Medicinal Chemistry Letters, October 2016, Elsevier

    Prof Hirokazu Arimoto

  5. Strategies for construction of the all-carbon macrocyclic skeleton of the ansamycin antibiotic—kendomycin

    Article • The Journal of Antibiotics, February 2016, Nature

    Prof Hirokazu Arimoto

  6. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang

  7. Roles of 8-nitro-cGMP in autophagy regulation

    Article • BMC Pharmacology and Toxicology, September 2015, Springer Science + Business Media

    Prof Hirokazu Arimoto

  8. Binding properties of antimicrobial agents to dipeptide terminal of lipid II using surface plasmon resonance

    Article • Analytical Biochemistry, May 2014, Elsevier

    Prof Hirokazu Arimoto

  9. Total Synthesis of the Antibiotic Kendomycin: A Macrocyclization Using the Tsuji-Trost Etherification

    Article • Angewandte Chemie, March 2014, Wiley

    Prof Hirokazu Arimoto

  10. Total Synthesis of the Antibiotic Kendomycin: A Macrocyclization Using the Tsuji-Trost Etherification

    Article • Angewandte Chemie International Edition, March 2014, Wiley

    Prof Hirokazu Arimoto

  11. Synthesis of 15N-labeled 4-oxo-2,2,6,6-tetraethylpiperidine nitroxide for EPR brain imaging

    Article • Tetrahedron Letters, March 2014, Elsevier

    Prof Hirokazu Arimoto

  12. Unexpected dehomologation of primary alcohols to one-carbon shorter carboxylic acids using o-iodoxybenzoic acid (IBX)

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  13. Binding Properties of Antimicrobial Agents to Lipid Membranes Using Surface Plasmon Resonance

    Article • Biological and Pharmaceutical Bulletin, January 2014, Pharmaceutical Society of Japan

    Prof Hirokazu Arimoto

  14. Endogenous Nitrated Nucleotide Is a Key Mediator of Autophagy and Innate Defense against Bacteria

    Article • Molecular Cell, December 2013, Elsevier

    Prof Hirokazu Arimoto

  15. Enantioselective Total Synthesis of Pinnaic Acid and Halichlorine

    Article • Chemistry - An Asian Journal, October 2013, Wiley

    Prof Hirokazu Arimoto

  16. Staphylococcus aureusPenicillin-Binding Protein 2 Can Use Depsi-Lipid II Derived from Vancomycin-Resistant Strains for Cell Wall Synthesis

    Article • Chemistry - A European Journal, July 2013, Wiley

    Prof Hirokazu Arimoto

  17. Fluorescent Probes for Live Cell Imaging of Endogenous Guanine Nitration

    Article • ChemBioChem, May 2013, Wiley

    Prof Hirokazu Arimoto

  18. Simultaneous Imaging of an Enantiomer Pair by Electron Paramagnetic Resonance Using Isotopic Nitrogen Labeling

    Article • Analytical Chemistry, January 2013, American Chemical Society (ACS)

    Prof Hirokazu Arimoto

  19. Elucidation of the Active Conformation of Vancomycin Dimers with Antibacterial Activity against Vancomycin-Resistant Bacteria

    Article • Chemistry - A European Journal, August 2012, Wiley

    Prof Hirokazu Arimoto

  20. Recent insights into natural venoms

    Article • Pure and Applied Chemistry, January 2012, De Gruyter

    Prof Hirokazu Arimoto

  21. Mapping of a lipoglycopeptide antibiotic binding site on Staphylococcus aureus penicillin-binding protein 2 using a vancomycin photoaffinity analogue

    Article • MedChemComm, January 2012, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  22. Nitric oxide promotes recycling of 8-nitro-cGMP, a cytoprotective mediator, into intact cGMP in cells

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  23. Chemical Approaches for Understanding and Controlling Infectious Diseases

    Article • January 2012, Springer Science + Business Media

    Prof Hirokazu Arimoto

  24. Pinnarine, Another Member of the Halichlorine Family. Isolation and Preparation from Pinnaic Acid

    Article • Journal of Natural Products, May 2011, American Chemical Society (ACS)

    Prof Hirokazu Arimoto

  25. New insight into the mode of action of vancomycin dimers in bacterial cell wall synthesis

    Article • MedChemComm, January 2011, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  26. One-pot reductive cleavage of exo-olefin to methylene with a mild ozonolysis-Clemmensen reduction sequence

    Article • Tetrahedron Letters, August 2010, Elsevier

    Prof Hirokazu Arimoto

  27. Regulation of Redox Signaling Involving Chemical Conjugation of Protein Thiols by Nitric Oxide and Electrophiles

    Article • Bioconjugate Chemistry, July 2010, American Chemical Society (ACS)

    Prof Hirokazu Arimoto

  28. Discovery of a Novel Series of Semisynthetic Vancomycin Derivatives Effective against Vancomycin-Resistant Bacteria

    Article • Journal of Medicinal Chemistry, March 2010, American Chemical Society (ACS)

    Prof Hirokazu Arimoto

  29. Traceable Amino Acid Analyses of Proteins and Peptides by Isotope-Dilution Mass Spectrometry Using Precolumn Derivatization Reagent

    Article • Analytical Sciences, January 2010, Japan Society for Analytical Chemistry

    Prof Hirokazu Arimoto

  30. Recent Progress in the Medicinal Chemistry of Vancomycin

    Article • Journal of Synthetic Organic Chemistry Japan, January 2010, The Society of Synthetic Organic Chemistry, Japan

    Prof Hirokazu Arimoto

  31. Recent aspects of chemical ecology: Natural toxins, coral communities, and symbiotic relationships

    Article • Pure and Applied Chemistry, January 2009, De Gruyter

    Prof Hirokazu Arimoto

  32. A Transannular Diels-Alder Strategy to the Construction of the CDE Ring System of Nakiterpiosin

    Article • Heterocycles, January 2009, Japan Institute of Heterocyclic Chemistry

    Prof Hirokazu Arimoto

  33. The conformational features of palytoxin in aqueous solution

    Article • Tetrahedron, August 2008, Elsevier

    Prof Hirokazu Arimoto

  34. 8-Nitroguanosines as chemical probes of the protein S-guanylation

    Article • Chemical Communications, January 2008, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  35. Synthesis of Pinnaic Acid

    Article • Synfacts, December 2007, Thieme Publishing Group

    Prof Hirokazu Arimoto

  36. 10.1080/15548627.2015.1100356

    Article • Nature Methods, September 2007, Nature

    Prof Hirokazu Arimoto

  37. Asymmetric Total Synthesis of Pinnaic Acid

    Article • Angewandte Chemie, July 2007, Wiley

    Prof Hirokazu Arimoto

  38. Asymmetric Total Synthesis of Pinnaic Acid

    Article • Angewandte Chemie International Edition, July 2007, Wiley

    Prof Hirokazu Arimoto

  39. Studies toward the total synthesis of nakiterpiosin: construction of the CDE ring system by a transannular Diels–Alder strategy

    Article • Tetrahedron Letters, July 2007, Elsevier

    Prof Hirokazu Arimoto

  40. Ring-closing Metathesis Approach to a 16-Membered Macrocycle of Kendomycin

    Article • Chemistry Letters, June 2007, The Chemical Society of Japan

    Prof Hirokazu Arimoto

  41. Erratum to “Identification of proteins from venom of the paralytic spider wasp, Cyphononyx dorsalis”[Insect Biochem. Mol. Biol. 37 (2007) 278–286]

    Article • Insect Biochemistry and Molecular Biology, May 2007, Elsevier

    Prof Hirokazu Arimoto

  42. Identification of proteins from venom of the paralytic spider wasp, Cyphononyx dorsalis

    Article • Insect Biochemistry and Molecular Biology, March 2007, Elsevier

    Prof Hirokazu Arimoto

  43. Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  44. Molecular shape of palytoxin in aqueous solution

    Article • Organic & Biomolecular Chemistry, January 2007, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  45. Effect of Ascorbic Acid on the Chemiluminescence of Polyphenols

    Article • Bioscience Biotechnology and Biochemistry, June 2006, Taylor & Francis

    Prof Hirokazu Arimoto

  46. Important Natural Products

    Article • April 2006, Wiley

    Prof Hirokazu Arimoto

  47. Concise Synthesis of the Plant Growth Regulator Theobroxide

    Article • Journal of Agricultural and Food Chemistry, May 2005, American Chemical Society (ACS)

    Prof Hirokazu Arimoto

  48. Synthetic studies on sugar-fused erinacines

    Article • Organic & Biomolecular Chemistry, January 2005, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  49. Nakiterpiosin and nakiterpiosinone, novel cytotoxic C-nor-D-homosteroids from the Okinawan sponge Terpios hoshinota

    Article • Tetrahedron, August 2004, Elsevier

    Prof Hirokazu Arimoto

  50. Synthesis of the tricyclic core of halichlorine

    Article • Chemical Communications, January 2004, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  51. Synthetic approach to kendomycin: preparation of the C-glycosidic coreElectronic supplementary information (ESI) available: selected spectral data for compounds 7, 8, 10, 11, 12, 15, 16, 17, 18, and 2. See http://www.rsc.org/suppdata/cc/b4/b402391a/

    Article • Chemical Communications, January 2004, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  52. Enantioselective Synthesis of the Spirotetracyclic Carbon Core of Mangicols by Using a Stereoselective Transannular Diels–Alder Strategy

    Article • Angewandte Chemie International Edition, January 2004, Wiley

    Prof Hirokazu Arimoto

  53. Enantioselective Synthesis of the Spirotetracyclic Carbon Core of Mangicols by Using a Stereoselective Transannular Diels–Alder Strategy

    Article • Angewandte Chemie, January 2004, Wiley

    Prof Hirokazu Arimoto

  54. Effects of β-sheet breaker peptide polymers on scrapie-infected mouse neuroblastoma cells and their affinities to prion protein fragment PrP(81–145)

    Article • Organic & Biomolecular Chemistry, January 2003, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  55. Synthesis of (±)-Pinnaic Acid

    Article • Heterocycles, January 2003, Japan Institute of Heterocyclic Chemistry

    Prof Hirokazu Arimoto

  56. Affinity of a vancomycin polymer with bacterial surface models

    Article • Tetrahedron Letters, May 2001, Elsevier

    Prof Hirokazu Arimoto

  57. Evolution of a Gram-Scale Synthesis of (+)-Discodermolide

    Article • Journal of the American Chemical Society, September 2000, American Chemical Society (ACS)

    Prof Hirokazu Arimoto

  58. Gram-Scale Synthesis of (+)-Discodermolide

    Article • Organic Letters, June 2000, American Chemical Society (ACS)

    Prof Hirokazu Arimoto

  59. Isolation and Structure of Kasarin, a Novel Azetinone Compound, Isolated from a Marine Microorganism

    Article • Heterocycles, January 2000, Japan Institute of Heterocyclic Chemistry

    Prof Hirokazu Arimoto

  60. Gram-Scale Synthesis of (+)-Discodermolide

    Article • Organic Letters, December 1999, American Chemical Society (ACS)

    Prof Hirokazu Arimoto

  61. Isolation and structures of haterumalides NA, NB, NC, ND, and NE, novel macrolides from an Okinawan Sponge Ircinia sp.

    Article • Tetrahedron Letters, August 1999, Elsevier

    Prof Hirokazu Arimoto

  62. Synthesis of pinnaic acid; Asymmetric construction of spirocyclic core

    Article • Tetrahedron Letters, April 1999, Elsevier

    Prof Hirokazu Arimoto

  63. Multi-valent polymer of vancomycin: enhanced antibacterial activity against VRE

    Article • Chemical Communications, January 1999, Royal Society of Chemistry

    Prof Hirokazu Arimoto

  64. Synthesis and absolute stereochemistry of tanzawaic acid (GS-1302)

    Article • Tetrahedron Letters, December 1998, Elsevier

    Prof Hirokazu Arimoto

  65. Anomalous Epoxide Formation Upon Wittig Olefination With 1-Iodoethyl Triphenylphosphonium Ylide

    Article • Synlett, July 1998, Thieme Publishing Group

    Prof Hirokazu Arimoto

  66. Absolute stereochemistry of halichlorine; A potent inhibitor of VCAM-1 induction

    Article • Tetrahedron Letters, February 1998, Elsevier

    Prof Hirokazu Arimoto

  67. Total synthesis of allixin; an anti-tumor promoter from garlic

    Article • Tetrahedron Letters, November 1997, Elsevier

    Prof Hirokazu Arimoto

  68. Tanzawaic Acids A, B, C, and D: Inhibitors of Superoxide Anion Production fromPenicillium citrinum

    Article • Chemistry Letters, September 1997, The Chemical Society of Japan

    Prof Hirokazu Arimoto

  69. Vallartanone B: Synthesis and related studies

    Article • Tetrahedron, October 1996, Elsevier

    Prof Hirokazu Arimoto

  70. Synthesis and revised structure of vallartanone B

    Article • Tetrahedron Letters, July 1996, Elsevier

    Prof Hirokazu Arimoto

  71. Preparation and Properties of 1,1′-Disubstituted Trichotomine Derivatives with a Twisted C=C Bond

    Article • Bulletin of the Chemical Society of Japan, June 1996, The Chemical Society of Japan

    Prof Hirokazu Arimoto

  72. Two New 7-Geranyloxycoumarins from the Bark of Aegle Marmelos, an Indonesian Medicinal Plant

    Article • Chemistry Letters, October 1995, The Chemical Society of Japan

    Prof Hirokazu Arimoto

  73. Synthetic studies on fully substituted γ-pyrone-containing natural products: Total synthesis and structural revision of onchitriol I

    Article • Tetrahedron Letters, July 1995, Elsevier

    Prof Hirokazu Arimoto

  74. Synthetic studies on fully substituted γ-pyrone-containing natural products: The first total synthesis of onchitriol II

    Article • Tetrahedron Letters, December 1994, Elsevier

    Prof Hirokazu Arimoto

  75. Chemical properties of β—triketones: Reexamination of Albizati's tandem aldol process

    Article • Tetrahedron Letters, June 1994, Elsevier

    Prof Hirokazu Arimoto

  76. Synthetic studies on fully substituted γ-pyrone-containing natural products: The absolute configurations of Ilikonapyrone and peroniatriols I and II

    Article • Tetrahedron Letters, September 1993, Elsevier

    Prof Hirokazu Arimoto

  77. Synthetic studies on fully substituted γ-pyrone-containing natural products: synthesis of γ-pyrone derivatives obtained by decomposition of peroniatriols

    Article • Tetrahedron Letters, January 1990, Elsevier

    Prof Hirokazu Arimoto

  78. Mild conditions for cyclization of β-triketides to the corresponding γ-pyrones carrying adjacent chiral centers toward biomimetic synthesis of fully substituted γ-pyrone-containing natural products

    Article • Tetrahedron Letters, January 1990, Elsevier

    Prof Hirokazu Arimoto