All Stories

  1. NatD epigenetically activates FOXA2 expression to promote breast cancer progression by facilitating MMP14 expression
  2. Oncolytic viruses engineered to enforce cholesterol efflux restore tumor-associated macrophage phagocytosis and anti-tumor immunity in glioblastoma
  3. Oncolytic vaccinia virus expressing a bispecific T-cell engager enhances immune responses in EpCAM positive solid tumors
  4. Metabolic-related gene pairs signature analysis identifies ABCA1 expression levels on tumor-associated macrophages as a prognostic biomarker in primary IDHWT glioblastoma
  5. Distinguishing the pros and cons of metabolic reprogramming in oncolytic virus immunotherapy
  6. An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade
  7. Recombinant adenovirus expressing the fusion protein PD1PVR improves CD8+ T cell-mediated antitumor efficacy with long-term tumor-specific immune surveillance in hepatocellular carcinoma
  8. Recombinant oncolytic adenovirus expressing a soluble PVR elicits long-term antitumor immune surveillance
  9. Enhanced antitumor efficacy of a novel oncolytic vaccinia virus encoding a fully monoclonal antibody against T-cell immunoglobulin and ITIM domain (TIGIT)
  10. Liraglutide activates nature killer cell-mediated antitumor responses by inhibiting IL-6/STAT3 signaling in hepatocellular carcinoma
  11. Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor
  12. Pan-Cancer Analysis of Immune Cell Infiltration Identifies a Prognostic Immune-Cell Characteristic Score (ICCS) in Lung Adenocarcinoma
  13. Recombinant Adenovirus Expressing a Soluble Fusion Protein PD-1/CD137L Subverts the Suppression of CD8+ T Cells in HCC
  14. Graphene oxide arms oncolytic measles virus for improved effectiveness of cancer therapy
  15. Fludarabine as an Adjuvant Improves Newcastle Disease Virus-Mediated Antitumor Immunity in Hepatocellular Carcinoma
  16. A robust six-gene prognostic signature for prediction of both disease-free and overall survival in non-small cell lung cancer
  17. The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma
  18. CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma
  19. Carrier Cells for Delivery of Oncolytic Measles Virus into Tumors: Determinants of Efficient Loading
  20. Proof-of-principle that a decoy virus protects oncolytic measles virus against neutralizing antibodies
  21. NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression
  22. Oncolytic measles virus enhances antitumour responses of adoptive CD8+NKG2D+ cells in hepatocellular carcinoma treatment
  23. Subcellular‐Scale Drug Transport via Ultrasound‐Degradable Mesoporous Nanosilicon to Bypass Cancer Drug Resistance
  24. Plasmon-enhanced Raman spectroscopic metrics for in situ quantitative and dynamic assays of cell apoptosis and necrosis
  25. The Glutaminase-1 Inhibitor 968 Enhances Dihydroartemisinin-Mediated Antitumor Efficacy in Hepatocellular Carcinoma Cells
  26. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
  27. Photoacoustic “nanobombs” fight against undesirable vesicular compartmentalization of anticancer drugs
  28. Anti-angiogenic efficacy of 5′-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs
  29. Kidney-type glutaminase (GLS1) is a biomarker for pathologic diagnosis and prognosis of hepatocellular carcinoma
  30. Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma
  31. Hierarchical construction of a mechanically stable peptide–graphene oxide hybrid hydrogel for drug delivery and pulsatile triggered release in vivo
  32. Mitophagy in Viral Infections
  33. Mitophagy promotes replication of oncolytic Newcastle disease virus by blocking intrinsic apoptosis in lung cancer cells
  34. Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus
  35. Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice
  36. Mitophagy Enhances Oncolytic Measles Virus Replication by Mitigating DDX58/RIG-I-Like Receptor Signaling
  37. Multifunctional antitumor molecule 5′-triphosphate siRNA combining glutaminase silencing and RIG-I activation
  38. Central nervous system involvement in systemic malignant atrophic papulosis (Degos disease): a case report
  39. Therapeutic Efficacy of Bifunctional siRNA Combining TGF- 1 Silencing with RIG-I Activation in Pancreatic Cancer
  40. One-Step Photo Synthesis of Protein-Drug Nanoassemblies for Drug Delivery
  41. Photo synthesis of protein-based drug-delivery nanoparticles for active tumor targeting
  42. Abstract 2259: Oncolytic attenuated measles virus exploits autophagy for its replication and spreads by suppressing Rig-1 like receptors (RLRs) in non-small cell lung cancer cells
  43. An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma
  44. Immuntherapie des Pankreaskarzinoms mit immunstimulatorischer siRNA: Kombination von „gene silencing“ von TGF-beta mit RIG-I-vermittelter Immunaktivierung
  45. Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery
  46. Apoptosis-Inducing Cellular Vehicles for Cancer Gene Therapy