All Stories

  1. Pneumosepsis survival in the setting of obesity leads to persistent steatohepatitis and metabolic dysfunction

    Article • Hepatology Communications, August 2023, Wolters Kluwer Health

    Dave Bridges

  2. Cross-sectional association between blood cholesterol and calcium levels in genetically diverse strains of mice

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Dave Bridges

  3. Associations of bacterial enteropathogens with systemic inflammation, iron deficiency, and anemia in preschool-age children in southern Ghana

    Article • PLOS One, July 2022, PLOS

    Dave Bridges

  4. Gestational Early-Time Restricted Feeding Results in Sex-Specific Glucose Intolerance in Adult Male Mice

    Article • April 2022, Cold Spring Harbor Laboratory Press

    Dave Bridges

  5. Insulin Tolerance Test v1

    Article • March 2022, ZappyLab, Inc.

    Dave Bridges

  6. Diet-induced obesity in mice impairs host defense against Klebsiella pneumonia in vivo and glucose transport and bactericidal functions in neutrophils in vitro

    Article • AJP Lung Cellular and Molecular Physiology, January 2022, American Physiological Society

    Dave Bridges

  7. Activation of Adipocyte mTORC1 Increases Milk Lipids in a Mouse Model of Lactation

    Article • July 2021, Cold Spring Harbor Laboratory Press

    Dave Bridges

  8. Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models

    Article • Archives of Toxicology, March 2021, Springer Science + Business Media

    Dave Bridges

  9. Obesity Augments Glucocorticoid-Dependent Muscle Atrophy in Male C57BL/6J Mice

    Article • Biomedicines, October 2020, MDPI AG

    Dave Bridges

  10. Obesity Promotes Glucocorticoid-dependent Muscle Atrophy in Male C57BL/6J Mice.

    Article • August 2020, MDPI AG

    Dave Bridges

  11. Obesity promotes glucocorticoid-dependent muscle atrophy in male C57BL/6J mice

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Dave Bridges

  12. A peer evaluation training results in high-quality feedback, as measured over time in nutritional sciences graduate students

    Article • AJP Advances in Physiology Education, June 2020, American Physiological Society

    Dave Bridges

  13. Chronic high dietary sucrose induces sexually dimorphic metabolic adaptations in liver and adipose tissue

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Prahlad K Rao, Dave Bridges

  14. Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner

    Article • AJP Endocrinology and Metabolism, May 2020, American Physiological Society

    Dave Bridges

  15. The trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine induces progressive mitochondrial dysfunction in HTR-8/SVneo trophoblasts

    Article • Toxicology, November 2019, Elsevier

    Dave Bridges

  16. The Signaling Pathways Project, an integrated ‘omics knowledgebase for mammalian cellular signaling pathways

    Article • Scientific Data, October 2019, Springer Science + Business Media

    Zichen Wang, Dave Bridges

  17. AMPK directly activates mTORC2 to promote cell survival during acute energetic stress

    Article • Science Signaling, June 2019, American Association for the Advancement of Science

    Dave Bridges

  18. Tuberous sclerosis complex exhibits a new renal cystogenic mechanism

    Article • Physiological Reports, January 2019, Wiley

    Dave Bridges

  19. Higher baseline expression of the PTGS2 gene and greater decreases in total colonic fatty acid content predict greater decreases in colonic prostaglandin-E2 concentrations after dietary supplementation with ω-3 fatty acids

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, December 2018, Elsevier

    Dave Bridges

  20. Disruption of brain-derived neurotrophic factor production from individual promoters generates distinct body composition phenotypes in mice

    Article • AJP Endocrinology and Metabolism, December 2018, American Physiological Society

    Dave Bridges

  21. Sex-specific differences in hepatic steatosis in obese spontaneously hypertensive (SHROB) rats

    Article • Biology of Sex Differences, September 2018, Springer Science + Business Media

    Dave Bridges

  22. Glucocorticoid-Induced Metabolic Disturbances Are Exacerbated in Obese Male Mice

    Article • Endocrinology, April 2018, Endocrine Society

    Dave Bridges

  23. Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons

    Article • Molecular Autism, January 2018, Springer Science + Business Media

    Dave Bridges

  24. Glucocorticoid-Induced Metabolic Disturbances are Exacerbated in Obesity

    Article • September 2017, Cold Spring Harbor Laboratory Press

    Dave Bridges

  25. Secretory phospholipase A 2 group IIA modulates insulin sensitivity and metabolism

    Article • Journal of Lipid Research, June 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dave Bridges

  26. Androgen Receptor Agonists Increase Lean Mass, Improve Cardiopulmonary Functions, and Extend Survival in Preclinical Models of Duchenne Muscular Dystrophy

    Article • Human Molecular Genetics, April 2017, Oxford University Press (OUP)

    Dave Bridges, Stephania Cormier

  27. An estrogen receptor β-selective agonist inhibits non-alcoholic steatohepatitis in preclinical models by regulating bile acid and xenobiotic receptors

    Article • Experimental Biology and Medicine, January 2017, SAGE Publications

    Dave Bridges, Ramesh Narayanan

  28. Weight loss effects of Methotrexate and Cyclophosphamide

    Article • Oncotarget, January 2017, Impact Journals, LLC

    Dave Bridges

  29. Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue

    Article • The FASEB Journal, October 2016, Federation of American Societies For Experimental Biology (FASEB)

    Dr Dave Bridges, Dave Bridges, Heather Smallwood, Ramesh Narayanan

  30. Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice

    Article • AJP Endocrinology and Metabolism, September 2016, American Physiological Society

    Dave Bridges

  31. Exposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice

    Article • AJP Endocrinology and Metabolism, April 2016, American Physiological Society

    Dave Bridges, Stephania Cormier

  32. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang, Professor George Perry, Professor Godefridus J Peters, Shuo-Chien Ling, Professor Jiwu Wei, Deepak Shukla, Dave Bridges

  33. Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, December 2015, Elsevier

    Dave Bridges

  34. Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation

    Article • Bioscience Reports, November 2015, Portland Press Ltd.

    Dave Bridges

  35. Cytochrome P450 1B1 Contributes to the Development of Atherosclerosis and Hypertension in Apolipoprotein E–Deficient MiceNovelty and Significance

    Article • Hypertension, November 2015, Wolters Kluwer Health

    Dave Bridges

  36. Characterization of neurons from immortalized dental pulp stem cells for the study of neurogenetic disorders

    Article • Stem Cell Research, November 2015, Elsevier

    Dave Bridges

  37. Gene expression changes in subcutaneous adipose tissue due to Cushing's disease

    Article • Journal of Molecular Endocrinology, July 2015, Bioscientifica

    Dave Bridges, Irit Hochberg

  38. Acromegaly and Adipose Tissue

    Article • PLOS One, June 2015, PLOS

    Dave Bridges

  39. Phosphoinositides: Key modulators of energy metabolism

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, June 2015, Elsevier

    Dr Dave Bridges, Dave Bridges

  40. Muscle mTORC1 in flies

    Article • Scientific Reports, April 2015, Springer Science + Business Media

    Dave Bridges

  41. Zinc Finger Protein 407 (ZFP407) Regulates Insulin-stimulated Glucose Uptake and Glucose Transporter 4 ( Glut4 ) mRNA

    Article • Journal of Biological Chemistry, January 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Dave Bridges, Dave Bridges

  42. The role of TORC1 in muscle development in Drosophila.

    Article • November 2014, Cold Spring Harbor Laboratory Press

    Dave Bridges, Dr Dave Bridges

  43. Gene expression signature in adipose tissue of acromegaly patients

    Article • BMC Bioinformatics, September 2014, Springer Science + Business Media

    Dr Dave Bridges, Dave Bridges

  44. Phosphorylation of sterol regulatory element binding protein-1a by protein kinase A (PKA) regulates transcriptional activity

    Article • Biochemical and Biophysical Research Communications, July 2014, Elsevier

    Dr Dave Bridges, Dave Bridges

  45. The Lipid Kinase PI4KIII  Is Highly Expressed in Breast Tumors and Activates Akt in Cooperation with Rab11a

    Article • Molecular Cancer Research, June 2014, American Association for Cancer Research (AACR)

    Dr Dave Bridges, Dave Bridges

  46. Metabolic Crosstalk: Molecular Links Between Glycogen and Lipid Metabolism in Obesity

    Article • Diabetes, April 2014, American Diabetes Association

    Dr Dave Bridges, Dave Bridges

  47. Roles for PI(3,5)P2 in nutrient sensing through TORC1

    Article • Molecular Biology of the Cell, January 2014, American Society for Cell Biology (ASCB)

    Dr Dave Bridges, Dave Bridges

  48. Inhibition of AMPK Catabolic Action by GSK3

    Article • Molecular Cell, May 2013, Elsevier

    Dr Dave Bridges, Dave Bridges

  49. In vivo, Pikfyve generates PI(3,5)P 2 , which serves as both a signaling lipid and the major precursor for PI5P

    Article • Proceedings of the National Academy of Sciences, October 2012, Proceedings of the National Academy of Sciences

    Dr Dave Bridges, Dave Bridges

  50. TC10 Is Regulated by Caveolin in 3T3-L1 Adipocytes

    Article • PLOS One, August 2012, PLOS

    Dr Dave Bridges, Dave Bridges

  51. Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1

    Article • Molecular Biology of the Cell, June 2012, American Society for Cell Biology (ASCB)

    Dr Dave Bridges, Dave Bridges

  52. Rab5 Proteins Regulate Activation and Localization of Target of Rapamycin Complex 1

    Article • Journal of Biological Chemistry, April 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Dave Bridges, Dave Bridges

  53. Guidelines for the use and interpretation of assays for monitoring autophagy

    Article • Autophagy, April 2012, Taylor & Francis

    Dave Bridges, Professor CIRO ISIDORO, Professor George Perry, Dr Takeshi Noda, Professor Nektarios Tavernarakis, Matthias Gaestel, Dr Francesca Demarchi, Maria Vaccaro, Juan Segura-Aguilar, Leonardo Travassos, Manoj B Menon, Isabelle Dugail, Dr Legembre Patrick, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Professor Godefridus J Peters, Professor Brigitte Galliot, Professor Luca Scorrano

  54. p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity

    Article • Proceedings of the National Academy of Sciences, March 2012, Proceedings of the National Academy of Sciences

    Dr Dave Bridges, Dave Bridges

  55. Phosphoinositides in Insulin Action and Diabetes

    Article • January 2012, Springer Science + Business Media

    Dave Bridges

  56. Faculty of 1000 evaluation for mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase.

    Article • November 2011, Faculty of 1000, Ltd.

    Dave Bridges

  57. Insulin Stimulates Phosphatidylinositol 3-Phosphate Production via the Activation of Rab5

    Article • Molecular Biology of the Cell, April 2008, American Society for Cell Biology (ASCB)

    Dr Dave Bridges, Dave Bridges

  58. Identification and characterization of D-AKAP1 as a major adipocyte PKA and PP1 binding protein

    Article • Biochemical and Biophysical Research Communications, July 2006, Elsevier

    Dr Dave Bridges, Dave Bridges

  59. 14-3-3 Proteins: A Number of Functions for a Numbered Protein

    Article • Science Signaling, August 2005, American Association for the Advancement of Science

    Dr Dave Bridges, Dave Bridges

  60. Article • BMC Bioinformatics, January 2005, Springer Science + Business Media

    Dave Bridges

  61. 14-3-3 Proteins: A Number of Functions for a Numbered Protein

    Article • Science Signaling, July 2004, American Association for the Advancement of Science

    Dr Dave Bridges, Dave Bridges

  62. Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays

    Article • European Journal of Biochemistry, March 2003, Wiley

    Carol MacKintosh, Dr Dave Bridges, Dave Bridges

  63. Detection of multiple splice variants of the nuclear protein phosphatase 1 regulator sds22 in rat liver nuclei

    Article • Biochemistry and Cell Biology, December 2002, Canadian Science Publishing

    Dr Dave Bridges, Dave Bridges

  64. The p11 Subunit of Annexin II Heterotetramer Is Regulated by Basic Carboxypeptidase †

    Article • Biochemistry, April 2002, American Chemical Society (ACS)

    Dave Bridges

  65. Faculty of 1000 evaluation for Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.

    Article • Faculty of 1000, Ltd.

    Dave Bridges

  66. Faculty of 1000 evaluation for Isoform-specific targeting of PKA to multivesicular bodies.

    Article • Faculty of 1000, Ltd.

    Dave Bridges

  67. Faculty of 1000 evaluation for Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes.

    Article • Faculty of 1000, Ltd.

    Dave Bridges