All Stories

  1. Bridging neurotrophic factors and bioactive peptides to Alzheimer's disease

    Article • Ageing Research Reviews, February 2024, Elsevier

    Ning Chen

  2. Unraveling precision exercise: A journey from efficacy to molecular insights

    Article • Advanced Exercise and Health Science, January 2024, Elsevier

    Ning Chen

  3. Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease

    Article • Journal of Neuroinflammation, March 2023, Springer Science + Business Media

    Ning Chen

  4. The Amyloid-Beta Clearance: From Molecular Targets to Glial and Neural Cells

    Article • Biomolecules, February 2023, MDPI AG

    Ning Chen

  5. MicroRNA profiling of different exercise interventions for alleviating skeletal muscle atrophy in naturally aging rats

    Article • Journal of Cachexia Sarcopenia and Muscle, December 2022, Wiley

    Ning Chen

  6. Corn peptide enhances exercise performance and prevents myocardial damage of mice caused by overtraining through activating autophagy

    Article • Journal of Functional Foods, October 2022, Elsevier

    Ning Chen

  7. Irisin, an exercise-induced bioactive peptide beneficial for health promotion during aging process

    Article • Ageing Research Reviews, September 2022, Elsevier

    Ning Chen

  8. Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trails

    Article • International Journal of Environmental Research and Public Health, August 2022, MDPI AG

    Ning Chen

  9. A Preclinical Systematic Review of the Effects of Chronic Exercise on Autophagy-Related Proteins in Aging Skeletal Muscle

    Article • Frontiers in Physiology, July 2022, Frontiers

    Ning Chen

  10. The Potential Role of miRNA-Regulated Autophagy in Alzheimer’s Disease

    Article • International Journal of Molecular Sciences, July 2022, MDPI AG

    Ning Chen

  11. Swimming Suppresses Cognitive Decline of HFD-Induced Obese Mice through Reversing Hippocampal Inflammation, Insulin Resistance, and BDNF Level

    Article • Nutrients, June 2022, MDPI AG

    Ning Chen

  12. Improved fatty acid profile reduces body fat and arterial stiffness in obese adolescents upon combinatorial intervention with exercise and dietary restriction

    Article • Journal of Exercise Science & Fitness, October 2021, Elsevier

    Ning Chen

  13. Exercise-Induced Benefits for Alzheimer’s Disease by Stimulating Mitophagy and Improving Mitochondrial Function

    Article • Frontiers in Aging Neuroscience, October 2021, Frontiers

    Ning Chen

  14. Lifelong Aerobic Exercise Alleviates Sarcopenia by Activating Autophagy and Inhibiting Protein Degradation via the AMPK/PGC-1α Signaling Pathway

    Article • Metabolites, May 2021, MDPI AG

    Ning Chen

  15. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Article • Autophagy, January 2021, Taylor & Francis

    MD, PhD Pierre-Louis Tharaux, Joilson O. Martins, Dr. rer. nat. Marc Herb, Dr Marcia R Cominetti, Alessio Di Fonzo, Christoph Gerhardt, Dr Mustafa Sahin, Dr Cinzia Volonté, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Prof Robert Bryson-Richardson, Professor Hyun Kyu Song, Prof Claudia Cavadas, Professor Po Sing Leung, Paula Ludovico, Javeed Shah, Giovanni Di Guardo, Dr Takeshi Noda, Professor Tullio Florio, Professor Kevin Coombs, Ning Chen

  16. Exercise-Induced Autophagy Suppresses Sarcopenia Through Akt/mTOR and Akt/FoxO3a Signal Pathways and AMPK-Mediated Mitochondrial Quality Control

    Article • Frontiers in Physiology, November 2020, Frontiers

    Ning Chen

  17. Do not neglect the role of circadian rhythm in muscle atrophy

    Article • Ageing Research Reviews, November 2020, Elsevier

    Ning Chen

  18. Spermidine as a target for cancer therapy

    Article • Pharmacological Research, September 2020, Elsevier

    Ning Chen

  19. Molecular Mechanisms For Exercise Intervention On Health Promotion: Interpretation From Autophagy And Target Product Development

    Article • Medicine & Science in Sports & Exercise, July 2020, Wolters Kluwer Health

    Ning Chen

  20. Exercise Attenuates Brain Aging by Rescuing Down-Regulated Wnt/β-Catenin Signaling in Aged Rats

    Article • Frontiers in Aging Neuroscience, April 2020, Frontiers

    Ning Chen

  21. The Regulation of microRNAs in Alzheimer's Disease

    Article • Frontiers in Neurology, April 2020, Frontiers

    Ning Chen

  22. Regulatory role of exercise-induced autophagy for sarcopenia

    Article • Experimental Gerontology, February 2020, Elsevier

    Ning Chen

  23. Elucidation for Underlying Mechanisms of Chronic Diseases and Potential Applications through Exercise-induced Autophagy

    Article • Medicine & Science in Sports & Exercise, June 2019, Wolters Kluwer Health

    Ning Chen

  24. Metformin‐induced autophagy and irisin improves INS‐1 cell function and survival in high‐glucose environment via AMPK/SIRT1/PGC‐1α signal pathway

    Article • Food Science & Nutrition, April 2019, Wiley

    Ning Chen

  25. Physical Activity Alleviates Cognitive Dysfunction of Alzheimer’s Disease through Regulating the mTOR Signaling Pathway

    Article • International Journal of Molecular Sciences, March 2019, MDPI AG

    Ning Chen

  26. A Novel Regulator of Type II Diabetes: MicroRNA-143

    Article • Trends in Endocrinology and Metabolism, June 2018, Elsevier

    Ning Chen

  27. Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.

    Article • Nutrients, March 2018, MDPI AG

    Ning Chen

  28. Trillium tschonoskii maxim saponin mitigates D-galactose-induced brain aging of rats through rescuing dysfunctional autophagy mediated by Rheb-mTOR signal pathway

    Article • Biomedicine & Pharmacotherapy, February 2018, Elsevier

    Ning Chen

  29. Regulatory Role of MicroRNAs in Muscle Atrophy during Exercise Intervention

    Article • International Journal of Molecular Sciences, January 2018, MDPI AG

    Ning Chen

  30. Ampelopsin is benefit for the prevention and treatment of cancers.

    Article • Anti-Cancer Agents in Medicinal Chemistry, January 2018, Bentham Science Publishers

    Ning Chen

  31. Autophagy Is a Promoter for Aerobic Exercise Performance during High Altitude Training

    Article • Oxidative Medicine and Cellular Longevity, January 2018, Hindawi Publishing Corporation

    Ning Chen

  32. Resveratrol as a Natural Autophagy Regulator for Prevention and Treatment of Alzheimer’s Disease

    Article • Nutrients, August 2017, MDPI AG

    Ning Chen

  33. Swimming attenuates d-galactose-induced brain aging via suppressing miR-34a-mediated autophagy impairment and abnormal mitochondrial dynamics

    Article • Journal of Applied Physiology, June 2017, American Physiological Society

    Ning Chen

  34. Ampelopsin attenuates the atrophy of skeletal muscle from d -gal-induced aging rats through activating AMPK/SIRT1/PGC-1α signaling cascade

    Article • Biomedicine & Pharmacotherapy, June 2017, Elsevier

    Ning Chen

  35. Lunasin: A promising polypeptide for the prevention and treatment of cancer

    Article • Oncology Letters, April 2017, Spandidos Publications

    Ning Chen

  36. Autophagy inhibitor 3-methyladenine alleviates overload-exercise-induced cardiac injury in rats

    Article • Acta Pharmacologica Sinica, March 2017, Springer Science + Business Media

    Ning Chen

  37. Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway

    Article • Oncotarget, February 2017, Impact Journals, LLC

    Ning Chen

  38. Atorvastatin inhibits the immediate-early response gene EGR1 and improves the functional profile of CD4+T-lymphocytes in acute coronary syndromes

    Article • Oncotarget, February 2017, Impact Journals, LLC

    Ning Chen

  39. Root-Securing and Brain-Fortifying Liquid Upregulates Caveolin-1 in Cell Model with Alzheimer’s Disease through Inhibiting Tau Phosphorylation

    Article • Neurology Research International, January 2017, Hindawi Publishing Corporation

    Ning Chen

  40. Ampelopsin attenuates brain aging of D-gal-induced rats through miR-34a-mediated SIRT1/mTOR signal pathway

    Article • Oncotarget, October 2016, Impact Journals, LLC

    Ning Chen

  41. Protective effect ofTrillium tschonoskiisaponin on CCl4-induced acute liver injury of rats through apoptosis inhibition

    Article • Canadian Journal of Physiology and Pharmacology, July 2016, Canadian Science Publishing

    Ning Chen

  42. Transcutaneous electrical acupoint stimulation alleviates adverse cardiac remodeling induced by overload training in rats

    Article • Journal of Applied Physiology, June 2016, American Physiological Society

    Ning Chen

  43. Exercise coupled with dietary restriction reduces oxidative stress in male adolescents with obesity

    Article • Journal of Sports Sciences, May 2016, Taylor & Francis

    Ning Chen

  44. MicroRNA-Regulated Proinflammatory Cytokines in Sarcopenia

    Article • Mediators of Inflammation, January 2016, Hindawi Publishing Corporation

    Ning Chen

  45. Autophagy as a Potential Target for Sarcopenia

    Article • Journal of Cellular Physiology, December 2015, Wiley

    Ning Chen

  46. Ampelopsin attenuates 6-OHDA-induced neurotoxicity by regulating GSK-3β/NRF2/ARE signalling

    Article • Journal of Functional Foods, December 2015, Elsevier

    Ning Chen

  47. Irisin, an exercise-induced myokine as a metabolic regulator: an updated narrative review

    Article • Diabetes/Metabolism Research and Reviews, June 2015, Wiley

    Ning Chen

  48. Daintain/AIF-1 accelerates the activation of insulin-like growth factor-1 receptor signaling pathway in HepG2 cells

    Article • Oncology Reports, May 2015, Spandidos Publications

    Ning Chen

  49. Autophagy is Required for Exercise Adaptation and Performance

    Article • Medicine & Science in Sports & Exercise, May 2015, Wolters Kluwer Health

    Ning Chen

  50. Autophagy-associated Targeting Pathways of Natural Products during Cancer Treatment

    Article • Asian Pacific Journal of Cancer Prevention, January 2015, Asian Pacific Organization for Cancer Prevention

    Ning Chen

  51. The Pak4 protein kinase is required for oncogenic transformation of MDA-MB-231 breast cancer cells

    Article • Oncogenesis, June 2013, Springer Science + Business Media

    Ning Chen

  52. Enzyme Sensors for Living Cells

    Article • January 2012, Elsevier

    Ning Chen

  53. Daintain/AIF-1 promotes breast cancer cell migration by up-regulated TNF-α via activate p38 MAPK signaling pathway

    Article • Breast Cancer Research and Treatment, April 2011, Springer Science + Business Media

    Ning Chen

  54. Autophagy as a therapeutic target in cancer

    Article • Cancer Biology & Therapy, January 2011, Taylor & Francis

    Ning Chen

  55. The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis

    Article • Oncogene, August 2010, Springer Science + Business Media

    Ning Chen

  56. Role and regulation of autophagy in cancer

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 2009, Elsevier

    Ning Chen

  57. Fluorescence complementation via EF-hand interactions

    Article • Journal of Biotechnology, July 2009, Elsevier

    Ning Chen

  58. Designing Protease Sensors for Real-Time Imaging of Trypsin Activation in Pancreatic Cancer Cells

    Article • Biochemistry, March 2009, American Chemical Society (ACS)

    Ning Chen