All Stories

  1. Targeting autophagy with natural products to prevent SARS-CoV-2 infection

    Article • Journal of Traditional and Complementary Medicine, January 2022, Elsevier

    Professor CIRO ISIDORO

  2. Resveratrol Contrasts LPA-Induced Ovarian Cancer Cell Migration and Platinum Resistance by Rescuing Hedgehog-Mediated Autophagy

    Article • Cells, November 2021, MDPI AG

    Professor CIRO ISIDORO

  3. Inhibition of Autophagy In Vivo Extends Methamphetamine Toxicity to Mesencephalic Cell Bodies

    Article • Pharmaceuticals, September 2021, MDPI AG

    Professor CIRO ISIDORO

  4. Caesalpinia mimosoides Leaf Extract Promotes Neurite Outgrowth and Inhibits BACE1 Activity in Mutant APP-Overexpressing Neuronal Neuro2a Cells

    Article • Pharmaceuticals, September 2021, MDPI AG

    Professor CIRO ISIDORO

  5. GNAi2/gip2-Regulated Transcriptome and Its Therapeutic Significance in Ovarian Cancer

    Article • Biomolecules, August 2021, MDPI AG

    Professor CIRO ISIDORO

  6. Cancer-Associated Fibroblast-Derived IL-6 Determines Unfavorable Prognosis in Cholangiocarcinoma by Affecting Autophagy-Associated Chemoresponse

    Article • Cancers, April 2021, MDPI AG

    Professor CIRO ISIDORO

  7. BECN1 and BRCA1 Deficiency Sensitizes Ovarian Cancer to Platinum Therapy and Confers Better Prognosis

    Article • Biomedicines, February 2021, MDPI AG

    Professor CIRO ISIDORO

  8. Chemopreventive and Anticancer Effects of Thymoquinone: Cellular and Molecular Targets

    Article • Journal of Cancer Prevention, September 2020, Korean Society of Cancer Prevention

    Professor CIRO ISIDORO

  9. Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome

    Article • Scientific Reports, January 2020, Springer Science + Business Media

    Professor CIRO ISIDORO

  10. Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells

    Article • Cell Communication and Signaling, August 2019, Springer Science + Business Media

    Professor CIRO ISIDORO

  11. Amino acid response by Halofuginone in Cancer cells triggers autophagy through proteasome degradation of mTOR

    Article • Cell Communication and Signaling, May 2019, Springer Science + Business Media

    Professor CIRO ISIDORO

  12. Ovarian cancer cell-derived lysophosphatidic acid induces glycolytic shift and cancer-associated fibroblast-phenotype in normal and peritumoral fibroblasts

    Article • Cancer Letters, February 2019, Elsevier

    Professor CIRO ISIDORO

  13. Autophagy-dependent toxicity of amino-functionalized nanoparticles in ovarian cancer cells

    Article • Journal of Materials Chemistry B, January 2019, Royal Society of Chemistry

    Professor CIRO ISIDORO

  14. Multifunctional Gd-based mesoporous silica nanotheranostic for anticancer drug delivery

    Article • Journal of Materials Chemistry B, January 2019, Royal Society of Chemistry

    Professor CIRO ISIDORO

  15. Dihydroartemisinin induces apoptosis and autophagy-dependent cell death in cholangiocarcinoma through a DAPK1-BECLIN1 pathway

    Article • Molecular Carcinogenesis, September 2018, Wiley

    Professor CIRO ISIDORO

  16. Resveratrol interrupts the pro-invasive communication between cancer associated fibroblasts and cholangiocarcinoma cells

    Article • Cancer Letters, August 2018, Elsevier

    Professor CIRO ISIDORO

  17. Lysophosphatidic Acid Induces Metabolic Reprogramming in Ovarian Cancer via a Pseudohypoxic Response

    Article • Cancer Research, January 2018, American Association for Cancer Research (AACR)

    Professor CIRO ISIDORO

  18. The metabolic cross-talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role

    Article • Medicinal Research Reviews, September 2017, Wiley

    Professor CIRO ISIDORO, Peti Thuwajit

  19. The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells

    Article • Molecular Carcinogenesis, September 2017, Wiley

    Professor CIRO ISIDORO

  20. Resveratrol protects neuronal-like cells expressing mutant Huntingtin from dopamine toxicity by rescuing ATG4-mediated autophagosome formation

    Article • Neurochemistry International, May 2017, Elsevier

    Professor CIRO ISIDORO

  21. Raman Spectrometric Detection Methods for Early and Non-Invasive Diagnosis of Alzheimer’s Disease

    Article • Journal of Alzheimer’s Disease, April 2017, IOS Press

    Professor CIRO ISIDORO

  22. Dopamine exacerbates mutant Huntingtin toxicity via oxidative-mediated inhibition of autophagy in SH-SY5Y neuroblastoma cells: Beneficial effects of anti-oxidant therapeutics

    Article • Neurochemistry International, December 2016, Elsevier

    Professor CIRO ISIDORO

  23. PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cells

    Article • Oncotarget, November 2016, Impact Journals, LLC

    Professor CIRO ISIDORO

  24. Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy

    Article • Molecular Carcinogenesis, November 2016, Wiley

    Professor CIRO ISIDORO

  25. B34 Dopamine imbalance in huntington’s disease: when the inhibition of autophagy can lead to cell catastrophe

    Article • Journal of Neurology Neurosurgery & Psychiatry, September 2016, BMJ

    Professor CIRO ISIDORO

  26. Transcriptomic analysis of the autophagy machinery in crustaceans

    Article • BMC Genomics, August 2016, Springer Science + Business Media

    Professor CIRO ISIDORO

  27. Coordinated Metabolic Changes and Modulation of Autophagy during Myogenesis

    Article • Frontiers in Physiology, June 2016, Frontiers

    Professor CIRO ISIDORO

  28. The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders

    Article • Medicinal Research Reviews, April 2016, Wiley

    Professor CIRO ISIDORO

  29. The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis

    Article • Cell Death and Disease, March 2016, Nature

    Professor CIRO ISIDORO

  30. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang, Professor George Perry, Professor Godefridus J Peters, Shuo-Chien Ling, Professor Jiwu Wei, Deepak Shukla

  31. Report from the Second International Conference of Traditional and Complementary Medicine on Health 2015

    Article • Journal of Traditional and Complementary Medicine, January 2016, Elsevier

    Professor CIRO ISIDORO

  32. Publishing scientifically sound papers in Traditional and Complementary Medicine

    Article • Journal of Traditional and Complementary Medicine, January 2016, Elsevier

    Professor CIRO ISIDORO

  33. Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells

    Article • Oncotarget, November 2015, Impact Journals, LLC

    Professor CIRO ISIDORO

  34. Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome

    Article • The Journal of Nutritional Biochemistry, September 2015, Elsevier

    Professor CIRO ISIDORO

  35. autophagy and neuroprotection

    Article • Autophagy, June 2015, Taylor & Francis

    Professor CIRO ISIDORO

  36. The Potential for Plant Derivatives against Acrylamide Neurotoxicity

    Article • Phytotherapy Research, April 2015, Wiley

    Professor CIRO ISIDORO

  37. Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis

    Article • EBioMedicine, March 2015, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  38. NaGdF4 Nanoparticles Coated with Functionalised Ethylenediaminetetraacetic Acid as Versatile Probes for Dual Optical and Magnetic Resonance Imaging

    Article • ChemPlusChem, October 2014, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  39. PTEN regulates plasma membrane expression of glucose transporter 1 and glucose uptake in thyroid cancer cells

    Article • August 2014, Bioscientifica

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  40. Turmeric Toxicity in A431 Epidermoid Cancer Cells Associates with Autophagy Degradation of Anti‐apoptotic and Anti‐autophagic p53 Mutant

    Article • Phytotherapy Research, July 2014, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  41. Epigenetic Control of Autophagy by MicroRNAs in Ovarian Cancer

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  42. Single Amino Acid Arginine Deprivation Triggers Prosurvival Autophagic Response in Ovarian Carcinoma SKOV3

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  43. Expression and Clinical Significance of the Autophagy Proteins BECLIN 1 and LC3 in Ovarian Cancer

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  44. Autophagy and thyroid carcinogenesis: genetic and epigenetic links

    Article • October 2013, Bioscientifica

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  45. Protection from UVB Toxicity in Human Keratinocytes by Thailand Native Herbs Extracts

    Article • Photochemistry and Photobiology, September 2013, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  46. Knockdown of cathepsin D in zebrafish fertilized eggs determines congenital myopathy

    Article • Bioscience Reports, April 2013, Portland Press Ltd.

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  47. Similarities and differences in the biogenesis, processing and lysosomal targeting between zebrafish and human pro-Cathepsin D: Functional implications

    Article • The International Journal of Biochemistry & Cell Biology, February 2013, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  48. Cathepsins: Getting in Shape for Lysosomal Proteolysis

    Article • January 2013, Springer Science + Business Media

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  49. Involvement of autophagy in ovarian cancer: a working hypothesis

    Article • Journal of Ovarian Research, September 2012, Springer Science + Business Media

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  50. Defective Autophagy in Parkinson’s Disease: Role of Oxidative Stress

    Article • Molecular Neurobiology, August 2012, Springer Science + Business Media

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  51. Dopamine induces apoptosis in APPswe-expressing Neuro2A cells following Pepstatin-sensitive proteolysis of APP in acid compartments

    Article • Brain Research, August 2012, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  52. Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups

    Article • International Journal of Nanomedicine, July 2012, Taylor & Francis

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  53. DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity

    Article • Cell Death and Differentiation, June 2012, Springer Science + Business Media

    Professor CIRO ISIDORO

  54. Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles

    Article • International Journal of Nanomedicine, April 2012, Dove Medical Press

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  55. Guidelines for the use and interpretation of assays for monitoring autophagy

    Article • Autophagy, April 2012, Taylor & Francis

    Dave Bridges, Professor CIRO ISIDORO, Professor George Perry, Dr Takeshi Noda, Professor Nektarios Tavernarakis, Matthias Gaestel, Dr Francesca Demarchi, Maria Vaccaro, Juan Segura-Aguilar, Leonardo Travassos, Manoj B Menon, Isabelle Dugail, Dr Legembre Patrick, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Professor Godefridus J Peters, Professor Brigitte Galliot, Professor Luca Scorrano

  56. Thyroid incidentaloma identified by 18 F‐fluorodeoxyglucose positron emission tomography with CT (FDG‐PET/CT): clinical and pathological relevance

    Article • Clinical Endocrinology, September 2011, Wiley

    Professor CIRO ISIDORO

  57. Induced autophagy reduces virus output in dengue infected monocytic cells

    Article • Virology, September 2011, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  58. Chelation of Lysosomal Iron Protects Dopaminergic SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide Toxicity by Precluding Autophagy and Akt Dephosphorylation

    Article • Toxicological Sciences, July 2011, Oxford University Press (OUP)

    Professor CIRO ISIDORO

  59. Knock-Down of Cathepsin D Affects the Retinal Pigment Epithelium, Impairs Swim-Bladder Ontogenesis and Causes Premature Death in Zebrafish

    Article • PLOS One, July 2011, PLOS

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  60. Patented Biomarkers for the Early Detection of Ovarian Cancer

    Article • Recent Patents on Biomarkers, March 2011, Bentham Science Publishers

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  61. Resveratrol Reduces the Invasive Growth and Promotes the Acquisition of a Long-Lasting Differentiated Phenotype in Human Glioblastoma Cells

    Article • Journal of Agricultural and Food Chemistry, March 2011, American Chemical Society (ACS)

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  62. Patented Biomarkers for the Early Detection of Ovarian Cancer

    Article • Recent Patents on Biomarkerse, January 2011, Bentham Science Publishers

    Professor CIRO ISIDORO

  63. The dilemma: Does tissue expression of cathepsin D reflect tumor malignancy? The question: Does the assay truly mirror cathepsin D mis-function in the tumor?

    Article • Cancer Biomarkers, October 2010, IOS Press

    Professor CIRO ISIDORO

  64. Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas

    Article • Modern Pathology, July 2010, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  65. Inhibition of PI3k Class III–Dependent Autophagy Prevents Apoptosis and Necrosis by Oxidative Stress in Dopaminergic Neuroblastoma Cells

    Article • Toxicological Sciences, June 2010, Oxford University Press (OUP)

    Professor CIRO ISIDORO

  66. Differential role of cathepsins B and L in autophagy-associated cell death induced by arsenic trioxide in U87 human glioblastoma cells

    Article • Biological Chemistry, May 2010, De Gruyter

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  67. Agonist monoclonal antibodies against HGF receptor protect cardiac muscle cells from apoptosis

    Article • AJP Heart and Circulatory Physiology, January 2010, American Physiological Society

    Professor CIRO ISIDORO

  68. High Expression of Cathepsin D in Non-Hodgkin’s Lymphomas Negatively Impacts on Clinical Outcome

    Article • Disease Markers, January 2010, Hindawi Publishing Corporation

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  69. Autophagy, lithium, and amyotrophic lateral sclerosis

    Article • Muscle & Nerve, July 2009, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  70. Chemotherapy drug response in ovarian cancer cells strictly depends on a cathepsin D‐Bax activation loop

    Article • Journal of Cellular and Molecular Medicine, June 2009, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  71. Photoactive Hybrid Nanomaterials: Indocyanine Immobilized in Mesoporous MCM-41 for “In-Cell” Bioimaging

    Article • ACS Applied Materials & Interfaces, March 2009, American Chemical Society (ACS)

    Professor Ciro Isidoro, Dr Enrica Gianotti, Professor CIRO ISIDORO

  72. Correction for Fornai et al. , Lithium delays progression of amyotrophic lateral sclerosis

    Article • Proceedings of the National Academy of Sciences, October 2008, Proceedings of the National Academy of Sciences

    Professor CIRO ISIDORO

  73. Role of Autophagy during Methamphetamine Neurotoxicity

    Article • Annals of the New York Academy of Sciences, October 2008, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  74. Akt Induces Apoptosis in Neuroblastoma Cells Expressing a C98X Vasopressin Mutant Following Autophagy Suppression

    Article • Journal of Neuroendocrinology, October 2008, Wiley

    Professor CIRO ISIDORO

  75. Prolactin Promotes the Secretion of Active Cathepsin D at the Basal Side of Rat Mammary Acini

    Article • Endocrinology, August 2008, Endocrine Society

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  76. Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

    Article • Journal of Neurochemistry, July 2008, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  77. Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium

    Article • Autophagy, May 2008, Taylor & Francis

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  78. Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

    Article • European Journal of Neuroscience, March 2008, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  79. Lithium delays progression of amyotrophic lateral sclerosis

    Article • Proceedings of the National Academy of Sciences, February 2008, Proceedings of the National Academy of Sciences

    Professor CIRO ISIDORO

  80. A fast and simple method for simultaneous mixed site‐specific mutagenesis of a wide coding sequence

    Article • Biotechnology and Applied Biochemistry, February 2008, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  81. Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes

    Article • Carcinogenesis, November 2007, Oxford University Press (OUP)

    Professor CIRO ISIDORO

  82. The expression of prolactin and its cathepsin D-mediated cleavage in the bovine corpus luteum vary with the estrous cycle

    Article • AJP Endocrinology and Metabolism, September 2007, American Physiological Society

    Professor CIRO ISIDORO

  83. Cathepsin D–Bax death pathway in oxidative stressed neuroblastoma cells

    Article • Free Radical Biology and Medicine, May 2007, Elsevier

    Professor CIRO ISIDORO

  84. Folding, activity and targeting of mutated human cathepsin D that cannot be processed into the double-chain form

    Article • The International Journal of Biochemistry & Cell Biology, January 2007, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  85. Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D

    Article • Carcinogenesis, November 2006, Oxford University Press (OUP)

    Professor CIRO ISIDORO

  86. PI3K-dependent lysosome exocytosis in nitric oxide-preconditioned hepatocytes

    Article • Free Radical Biology and Medicine, May 2006, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  87. Prognostic significance of microvessel density and vascular endothelial growth factor expression in sinonasal carcinomas☆

    Article • Human Pathology, April 2006, Elsevier

    Professor CIRO ISIDORO

  88. cFLIP expression correlates with tumour progression and patient outcome in non‐Hodgkin lymphomas of low grade of malignancy

    Article • British Journal of Haematology, January 2006, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  89. High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells

    Article • Protein Expression and Purification, January 2006, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  90. Autophagy-dependent cell survival and cell death in an autosomal dominant familial neurohypophyseal diabetes insipidus in vitro model

    Article • The FASEB Journal, June 2005, Federation of American Societies For Experimental Biology (FASEB)

    Professor CIRO ISIDORO

  91. Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene

    Article • The FASEB Journal, June 2005, Federation of American Societies For Experimental Biology (FASEB)

    Professor CIRO ISIDORO

  92. Cathepsin D released by lactating rat mammary epithelial cells is involved in prolactin cleavage under physiological conditions

    Article • Journal of Cell Science, October 2004, The Company of Biologists

    Professor CIRO ISIDORO

  93. Preconditioning-induced cytoprotection in hepatocytes requires Ca2+-dependent exocytosis of lysosomes

    Article • Journal of Cell Science, March 2004, The Company of Biologists

    Professor CIRO ISIDORO

  94. Destination ‘Lysosome’: a target organelle for tumour cell killing?

    Article • Journal of Molecular Recognition, September 2003, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  95. Endosomal-Lysosomal Proteolysis Mediates Death Signalling by TNFα, Not by Etoposide, in L929 Fibrosarcoma Cells: Evidence for an Active Role of Cathepsin D

    Article • Biological Chemistry, January 2002, De Gruyter

    Professor CIRO ISIDORO

  96. Increase in Ceramide Level Alters the Lysosomal Targeting of Cathepsin D prior to Onset of Apoptosis in HT-29 Colon Cancer Cells

    Article • Biological Chemistry, January 2002, De Gruyter

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  97. Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas

    Article • International Journal of Cancer, November 2001, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  98. Expression of protein kinase C ?1 confers resistance to TNF?- and paclitaxel-induced apoptosis in HT-29 colon carcinoma cells

    Article • International Journal of Cancer, January 2001, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  99. Transformation by oncogenic ras‐p21 alters the processing and subcellular localization of the lysosomal protease cathepsin D

    Article • Journal of Cellular Biochemistry, June 1999, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  100. Transformation by oncogenic ras-p21 alters the processing and subcellular localization of the lysosomal protease cathepsin D

    Article • Journal of Cellular Biochemistry, June 1999, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  101. Regulation of rat hepatocyte protein kinase C ? isoenzymes by the lipid peroxidation product 4-hydroxy-2,3-nonenal: A signaling pathway to modulate vesicular transport of glycoproteins

    Article • Hepatology, May 1999, Wolters Kluwer Health

    Professor Ciro Isidoro, Professor Fiorella Biasi, Professor CIRO ISIDORO

  102. Lysosomal segregation of a mannose-rich glycoprotein imparted by the prosequence of myeloperoxidase

    Article • Journal of Cellular Biochemistry, November 1998, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  103. Human and hamster procathepsin D, although equally tagged with mannose-6-phosphate, are differentially targeted to lysosomes in transfected BHK cells

    Article • Cell and Tissue Research, April 1998, Springer Science + Business Media

    Professor CIRO ISIDORO

  104. Differentiation-induced changes in the content, secretion, and subcellular distribution of lysosomal cathepsins in the human colon cancer HT-29 cell line

    Article • Cell and Tissue Research, June 1997, Springer Science + Business Media

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  105. Mis-sorting of procathepsin D in metastogenic tumor cells is not due to impaired synthesis of the phosphomannosyl signal

    Article • International Journal of Cancer, March 1997, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  106. Differential targeting and processing of procathepsin D in normal and transformed murine 3T3 fibroblasts

    Article • International Journal of Cancer, January 1997, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  107. Exposed Thiols Confer Localization in the Endoplasmic Reticulum by Retention Rather than Retrieval

    Article • Journal of Biological Chemistry, October 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor CIRO ISIDORO

  108. Synthesis, maturation and extracellular release of procathepsin D as influenced by cell proliferation or transformation

    Article • International Journal of Cancer, December 1995, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  109. Differentiation-dependent autophagy controls the fate of newly synthesized N-linked glycoproteins in the colon adenocarcinoma HT-29 cell line

    Article • Biochemical Journal, July 1995, Portland Press Ltd.

    Professor CIRO ISIDORO

  110. Localization and Processing of Glycosylphosphatidylinositol-Anchored Cathepsin D

    Article • Biochemical and Biophysical Research Communications, June 1995, Elsevier

    Professor CIRO ISIDORO

  111. A Heterotrimeric G-protein Controls Autophagic Sequestration in the Human Colon Cancer Cell Line HT-29

    Article • Journal of Biological Chemistry, January 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor CIRO ISIDORO

  112. Altered intracellular processing and enhanced secretion of procathepsin D in a highly deviated rat hepatoma

    Article • International Journal of Cancer, January 1995, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  113. Effects of Calcitriol on the Biogenesis of a Lysosomal Protease in Monocytes from Patients with Renal Failure

    Article • January 1994, Karger Publishers

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  114. Role of monocytes in cryoglobulinemia-associated nephritis

    Article • Kidney International, May 1993, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  115. Serum and Intracellular Detection of Cytokines in Patients Undergoing Chronic Hemodialysis

    Article • Artificial Organs, April 1992, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  116. Differential segregation of human and hamster cathepsin D in transfected baby-hàmster kidney cells

    Article • Biochemical Journal, January 1991, Portland Press Ltd.

    Professor CIRO ISIDORO

  117. Altered transport and processing of cathepsin D in human tumour cells with metastatic phenotype

    Article • European Journal of Cancer and Clinical Oncology, January 1991, Elsevier

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  118. Suppression of the ‘uncovering’ of mannose‐6‐phosphate residues in lysosomal enzymes in the presence of NH4Cl

    Article • FEBS Journal, August 1990, Wiley

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  119. Brefeldin A Prevents Uncovering but not Phosphorylation of the Recognition Marker in Cathepsin D

    Article • Biological Chemistry Hoppe-Seyler, January 1990, De Gruyter

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  120. Regulation of Protein Degradation in Neoplastic Cells

    Article • January 1988, Springer Science + Business Media

    Professor Ciro Isidoro, Professor CIRO ISIDORO

  121. Characterization of cathepsin D in ascites hepatoma cells and in the liver of tumour-bearing animals*1

    Article • Cell Biology International Reports, June 1986, Wiley

    Professor CIRO ISIDORO

  122. Regulation of lysosomal cysteine-proteinase activities in 3T3 and SV-3T3 cells*

    Article • Cell Biology International Reports, March 1986, Wiley

    Professor CIRO ISIDORO

  123. The transport of soluble lysosomal hydrolases from the Golgi complex to lysosomes

    Article • Springer Science + Business Media

    Professor Ciro Isidoro, Professor CIRO ISIDORO