All Stories

  1. Neuroendocrine timekeepers: changes in normal and premature aging
  2. Circadian rhythms are disrupted in patients and preclinical models of Machado-Joseph disease
  3. The Therapeutic Potential of Melatonin and Its Novel Synthetic Analogs in Circadian Rhythm Sleep Disorders, Inflammation‐Associated Pathologies, and Neurodegenerative Diseases
  4. The (un)known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications
  5. Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
  6. Senescent cell transplantation into the skin induces age‐related peripheral dysfunction and cognitive decline
  7. Modeling hypothalamic pathophysiology in vitro for metabolic, circadian, and sleep disorders
  8. Lipodystrophy as a target to delay premature aging
  9. Ghrelin delays premature aging in Hutchinson‐Gilford progeria syndrome
  10. Primary cilia shape hallmarks of health and aging
  11. Cellular Senescence: From Mechanisms to Current Biomarkers and Senotherapies
  12. Ataxin-2 in the hypothalamus at the crossroads between metabolism and clock genes
  13. The impact of insomnia on frailty and the hallmarks of aging
  14. Obstructive sleep apnea impact on physiology: insights from a mouse model and a case-control study
  15. The impact of obstructive sleep apnea treatment with continuous positive airway pressure on the biological clock
  16. SIRT1 activation and its circadian clock control: a promising approach against (frailty in) neurodegenerative disorders
  17. Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis
  18. SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway
  19. PET Imaging of the Neuropeptide Y System: A Systematic Review
  20. A look on food intake and satiety: from humans to rodent models
  21. Skin senescence: mechanisms and impact on whole-body aging
  22. Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics
  23. Small-molecule modulators of the circadian clock: Pharmacological potentials in circadian-related diseases
  24. The NutriClock Study Protocol - Assessing the Impact of a Chrononutrition Intervention in Patients With Cardiometabolic Disturbances
  25. PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons
  26. Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea
  27. Neuropeptide Y (NPY) intranasal delivery alleviates Machado–Joseph disease
  28. Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: An unexpectable link?
  29. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
  30. The Superpowers of Our Sleep
  31. Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats
  32. Trehalose alleviates the phenotype of Machado–Joseph disease mouse models
  33. Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells
  34. Long-Term Continuous Positive Airway Pressure Treatment Ameliorates Biological Clock Disruptions in Obstructive Sleep Apnea
  35. Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases
  36. The importance of determining circadian parameters in pharmacological studies
  37. In vitro susceptibility of Trypanosoma brucei brucei to selected essential oils and their major components
  38. Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice
  39. Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis
  40. Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress
  41. Obstructive Sleep Apnea and Hallmarks of Aging
  42. The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes
  43. Quizzes as an active learning strategy: A study with students of pharmaceutical sciences
  44. Unraveling the Role of Ataxin-2 in Metabolism
  45. Hypoxia mimetic induces lipid accumulation through mitochondrial dysfunction and stimulates autophagy in murine preadipocyte cell line
  46. Hypothalamic Dysfunction in Obesity and Metabolic Disorders
  47. Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases
  48. Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation
  49. The pathophysiology of defective proteostasis in the hypothalamus — from obesity to ageing
  50. Antileishmanial activity of antiretroviral drugs combined with miltefosine
  51. Corrigendum to “Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes” [neuropeptides 46/6 (2012) 359–366]
  52. Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway
  53. The Adenosinergic System in Diabetic Retinopathy
  54. Neuropeptide Y: An Anti-Aging Player?
  55. Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism
  56. Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress
  57. Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective ActionsIn Vitro
  58. Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado–Joseph disease
  59. Neuropeptide Y system in the retina: From localization to function
  60. NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?
  61. Neuropeptide Y stimulates autophagy in hypothalamic neurons
  62. Hypothalamic involvement in premature aging laminopathies
  63. Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress
  64. Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro
  65. Role of hypothalamic neurogenesis in feeding regulation
  66. MicroRNAs in Obesity and Metabolism
  67. Catecholamine Release Modulation by Adenosine Through A2a Receptors in Mouse Chromaffin Cells in Culture
  68. Catecholamine Release Modulation by Adenosine through A2AReceptors in Mouse Chromaffin Cell Culture
  69. Chronic Unpredictable Stress Induces Catecholaminergic System Changes in Mouse Adrenal Gland
  70. Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection
  71. Progenitor Cells in Chromospheres: In Response to Arthur S. Tischler
  72. Effect of Diabetes/Hyperglycemia on the Rat Retinal Adenosinergic System
  73. Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate
  74. Neuropeptide Y Receptors Y 1 and Y 2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture
  75. Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes
  76. Isolation, Characterization, and Differentiation of Progenitor Cells from Human Adult Adrenal Medulla
  77. Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression
  78. Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose
  79. Regulation of catecholamine release in human adrenal chromaffin cells by β-adrenoceptors
  80. Effects of 3,4-Methylenedioxymethamphetamine Administration on Retinal Physiology in the Rat
  81. Moderate Long-Term Modulation of Neuropeptide Y in Hypothalamic Arcuate Nucleus Induces Energy Balance Alterations in Adult Rats
  82. Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons
  83. Neuropeptide Y inhibits [Ca2+]ichanges in rat retinal neurons through NPY Y1, Y4, and Y5receptors
  84. Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1β: role of neuropeptide Y and nitric oxide
  85. Neuropeptide Y Family Peptides
  86. Stress-Induced Hypertension and Increased Sympathetic Activity in Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons
  87. Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia
  88. Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide
  89. Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy
  90. Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1receptors in mouse chromaffin cells
  91. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells
  92. NPY Y1 receptor is not involved in the hemodynamic response to an acute cold pressor test in mice
  93. Neuropeptide Y regulates catecholamine release evoked by interleukin-1β in mouse chromaffin cells
  94. Deletion of the neuropeptide Y (NPY) Y 1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion
  95. The Putative Neuroprotective Role of Neuropeptide Y in the Central Nervous System
  96. Neuropeptide Y expression, localization and cellular transducing effects in HUVEC
  97. Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats
  98. NPY, NPY receptors, and DPP IV activity are modulated by LPS, TNF-α and IFN-γ in HUVEC
  99. Blood sampling methodology is crucial for precise measurement of plasma catecholamines concentrations in mice
  100. Angiotensin II mediates catecholamine and neuropeptide Y secretion in human adrenal chromaffin cells through the AT1 receptor
  101. Neuropeptide Y and its receptors as potential therapeutic drug targets
  102. Catecholamine and Neuropeptide Y Secretion from Human Adrenal Chromaffin Cells
  103. Differential Secretion of Catecholamine and Neuropeptide Y in Response to KCl from Mice Chromaffin Cells
  104. Dibasic cleavage site is required for sorting to the regulated secretory pathway for both pro- and neuropeptide Y
  105. Interplay Between Galanin and Leptin in the Hypothalamic Control of Feeding via Corticotropin-Releasing Hormone and Neuropeptide Y
  106. NPY Regulates Catecholamine Secretion from Human Adrenal Chromaffin Cells
  107. Cardiovascular effects of fentanyl in conscious rats
  108. In vitro study of the interaction of Tilia europeae L. aqueous extract with GABAA receptors in rat brain