All Stories

  1. Electrochemical magneto-immunoassay for detection of ADAM10 Alzheimer's biomarker using gold nanoparticles as label
  2. The Brain Health Diplomat's Toolkit: supporting brain health diplomacy leaders in Latin America and the Caribbean
  3. ADAM10 as a biomarker for Alzheimer's disease: A systematic review
  4. Nanoencapsulation of Ruthenium Complex Ru(ThySMet): A Strategy to Improve Selective Cytotoxicity Against Breast Tumor Cells in 2D and 3D Culture Models
  5. Protecting cognitive function in older adults with age-related hearing loss: Insights from The Irish Longitudinal Study on Ageing (TILDA) and the role of hearing aids
  6. New ruthenium(ii) complexes with cyclic thio- and semicarbazone: evaluation of cytotoxicity and effects on cell migration and apoptosis of lung cancer cells
  7. New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway
  8. Developments in scalable strategies for detecting early markers of cognitive decline
  9. Cytotoxic and antiparasitic activities of diphosphine-metal complexes of group 10 containing acylthiourea as ligands
  10. Dynamics of Formation of Binuclear Metal Complexes: A New Cu(I) Compound with N ‐(2‐thiophenecarbonyl)‐ N’ ‐(3‐Cl, 4‐F‐phenyl)thiourea as Ligand
  11. Vitamin D deficiency predicts 30-day hospital mortality of adults with COVID-19
  12. Diabetes predicts cognitive decline in the Irish population
  13. Biomarkers for Different Types of Dementia with a Therapeutic Focus
  14. Apolipoprotein E ε4 allele impairs cortical activity in healthy aging and Alzheimer’s disease
  15. Ruthenium(ii)-diphosphine complexes containing acylthiourea ligands are effective against lung and breast cancers
  16. Handicap auditivo e fragilidade em idosos da comunidade
  17. Cytotoxic and Antiparasitic Activities of Diphosphine-Metal Complexes of Group 10 Containing Acylthiourea as Ligands
  18. Experimental and Theoretical DFT Study of Cu(I)/N,N-Disubstituted-N′-acylthioureato Anticancer Complexes: Actin Cytoskeleton and Induction of Death by Apoptosis in Triple-Negative Breast Tumor Cells
  19. Phenylalanine and COVID-19: Tracking disease severity markers
  20. Plasma 25-hydroxyvitamin D levels, quality of life, inflammation and depression in older adults: Are they related?
  21. Comorbidities predict 30-day hospital mortality of older adults with COVID-19
  22. Recent progresses on p-tau as a blood-based Alzheimer’s disease biomarker
  23. Associations between inflammatory markers and muscle strength in older adults according to the presence or absence of obesity
  24. Poluição do ar e sua relação com a epilepsia
  25. Is there any relation between the elevations in liver transaminases and the severity of COVID-19?
  26. IL-6 and IL-10 are associated with disease severity and higher comorbidity in adults with COVID-19
  27. Efficacy of Gene Therapy to Restore Cognition in Alzheimer’s Disease: A Systematic Review
  28. [6]-Gingerol-Derived Semi-Synthetic Compound SSi6 Inhibits Tumor Growth and Metastatic Dissemination in Triple-Negative Breast Cancer Xenograft Models
  29. Scavenging capacity and cytotoxicity of new Ru(II)-diphosphine/α-amino acid complexes
  30. [10]-Gingerol-Loaded Nanoemulsion and its Biological Effects on Triple-Negative Breast Cancer Cells
  31. Are body fat and inflammatory markers independently associated with age-related muscle changes?
  32. ADAM10 as a biomarker of mild cognitive impairment but not of cognitive frailty
  33. ADAM10 as a complimentary biomarker for mild Alzheimer's disease
  34. A systematic review and meta-analysis on cognitive frailty in community-dwelling older adults: risk and associated factors
  35. Preparation and characterization of [6]-gingerol/β-cyclodextrin inclusion complexes
  36. Levels of ADAM10 predict worse in cognition
  37. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
  38. A novel ruthenium(ii) gallic acid complex disrupts the actin cytoskeleton and inhibits migration, invasion and adhesion of triple negative breast tumor cells
  39. Lapachol in the Design of a New Ruthenium(II)-Diphosphine Complex as a Promising Anticancer Metallodrug
  40. ADAM10 as a biomarker for Alzheimer’s disease
  41. Cytotoxicity of ruthenium-N,N-disubstituted-N′-acylthioureas complexes
  42. Ruthenium(II) Phosphine/Mercapto Complexes: Their in Vitro Cytotoxicity Evaluation and Actions as Inhibitors of Topoisomerase and Proteasome Acting as Possible Triggers of Cell Death Induction
  43. A Systematic Review of Altered P300 Event-Related Potential in Apolipoprotein E4 (APOE4) Carriers
  44. ADAM10 plasma levels predict worsening in cognition of older adults: a 3-year follow-up study
  45. Copper transporter 1 affinity as a delivery strategy to improve the cytotoxic profile of rationally designed copper(II) complexes for cancer treatment
  46. Lycium barbarum polysaccharide fraction associated with photobiomodulation protects from epithelium thickness and collagen fragmentation in a model of cutaneous photodamage
  47. ADAM10 Plasma Levels Predict Worsening in Cognition of Older Adults: A 3-Year Follow-Up Study
  48. [10]-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models
  49. Antitumor activity of Pd(II) complexes with N,S or O,S coordination modes of acylthiourea ligands
  50. Polysaccharide‐rich hydrogel formulation combined with photobiomodulation repairs UV‐induced photodamage in mice skin
  51. Structure Elucidation and Absolute Configuration Determination of Nortriterpenoids from Picramnia glazioviana
  52. Blood-based Biomarkers of Alzheimer’s Disease: The Long and Winding Road
  53. Evaluation of the biological potential of ruthenium(II) complexes with cinnamic acid
  54. Selective Coordination Mode of Acylthiourea Ligands in Half-Sandwich Ru(II) Complexes and Their Cytotoxic Evaluation
  55. Early Diagnosis of Alzheimer’s Disease in Blood Using a Disposable Electrochemical Microfluidic Platform
  56. Vitamin D Deficient Older Adults Are More Prone to Have Metabolic Syndrome, but Not to a Greater Number of Metabolic Syndrome Parameters
  57. Historic concepts of dementia and Alzheimer's disease: From ancient times to the present
  58. SSi6 promotes cell death by apoptosis through cell cycle arrest and inhibits migration and invasion of MDA-MB-231 human breast cancer cells
  59. Acetylation of cedrelone increases its cytotoxic activity and reverts the malignant phenotype of breast cancer cells in 3D culture
  60. Cytotoxic and apoptotic effects of ternary silver(i) complexes bearing 2-formylpyridine thiosemicarbazones and 1,10-phenanthroline
  61. Factors associated with depressive symptoms in older adults in context of social vulnerability
  62. Ru(ii)-Naphthoquinone complexes with high selectivity for triple-negative breast cancer
  63. Ru(ii)/diclofenac-based complexes: DNA, BSA interaction and their anticancer evaluation against lung and breast tumor cells
  64. Ruthenium(II)-mercapto Complexes with Anticancer Activity Interact with Topoisomerase IB
  65. Silver(i) complexes of 3-methoxy-4-hydroxybenzaldehyde thiosemicarbazones and triphenylphosphine: structural, cytotoxicity, and apoptotic studies
  66. Three-dimensional cell culture models for metallodrug testing: induction of apoptosis and phenotypic reversion of breast cancer cells by thetrans-[Ru(PPh3)2(N,N-dimethyl-N-thiophenylthioureato-k2...
  67. Mapping Research in the Obesity, Adipose Tissue, and MicroRNA Field: A Bibliometric Analysis
  68. Alphavbeta3 integrin blocking inhibits apoptosis and induces autophagy in murine breast tumor cells
  69. Metastasis and cachexia: alongside in clinics, but not so in animal models
  70. Picraviane A and B: Nortriterpenes with limonoid-like skeletons containing a heptanolide E-ring system from Picramnia glazioviana
  71. [10]-Gingerol Affects Multiple Metastatic Processes and Induces Apoptosis in MDAMB- 231 Breast Tumor Cells
  72. Evaluation of the cytotoxicity on breast cancer cell of extracts and compounds isolated from Hyptis pectinata (L.) poit
  73. ADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker
  74. Metastasis inhibition in breast cancer by targeting cancer cell extravasation
  75. Ru(II)/N-N/PPh3 complexes as potential anticancer agents against MDA-MB-231 cancer cells (N-N = diimine or diamine)
  76. Label-free evaluation of small-molecule–protein interaction using magnetic capture and electrochemical detection
  77. Sarcopenia, frailty and their prevention by exercise
  78. Transport of the Ruthenium Complex [Ru(GA)(dppe)2]PF6 into Triple-Negative Breast Cancer Cells Is Facilitated by Transferrin Receptors
  79. Non-mutagenic Ru(ii) complexes: cytotoxicity, topoisomerase IB inhibition, DNA and HSA binding
  80. Anti-Proliferative and Anti-Migration Activity of Arene–Ruthenium(II) Complexes with Azole Therapeutic Agents
  81. Determination of in vitro absorption in Caco-2 monolayers of anticancer Ru(II)-based complexes acting as dual human topoisomerase and PARP inhibitors
  82. Higher levels of tumor necrosis factor β are associated with frailty in socially vulnerable community-dwelling older adults
  83. Hydrolysis reaction promotes changes in coordination mode of Ru(II)/acylthiourea organometallic complexes with cytotoxicity against human lung tumor cell lines
  84. The trans -[Ru(PPh 3 ) 2 ( N , N -dimethyl- N ′-thiophenylthioureato-k 2 O,S)(bipy)]PF 6 complex has pro-apoptotic effects on triple negative breast cancer cells and presents low toxicity in vivo
  85. Autophagy-dependent apoptosis is triggered by a semi-synthetic [6]-gingerol analogue in triple negative breast cancer cells
  86. Translation, Adaptation and Validation of Rapid Geriatric Assessment to the Brazilian Context
  87. Photobiomodulation of a flowable matrix in a human skin ex vivo model demonstrates energy-based enhancement of engraftment integration and remodeling
  88. A bibliometric analysis in oncology and nanomedicine areas
  89. Alpha-Secretase ADAM10 Regulation: Insights into Alzheimer’s Disease Treatment
  90. Fully disposable microfluidic electrochemical device for detection of estrogen receptor alpha breast cancer biomarker
  91. microRNA 221 Targets ADAM10 mRNA and is Downregulated in Alzheimer’s Disease
  92. Selective Ru(II)/lawsone complexes inhibiting tumor cell growth by apoptosis
  93. Cytotoxicity and anti-tumor effects of new ruthenium complexes on triple negative breast cancer cells
  94. A Review of Ruthenium Complexes Activities on Breast Cancer Cells
  95. [10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo
  96. Ruthenium(II)/triphenylphosphine complexes: An effective way to improve the cytotoxicity of lapachol
  98. [10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture
  99. Abstract B40: [10]-gingerol as a pro-apoptotic molecule in triple negative breast cancer
  100. Heteroleptic tris-chelate ruthenium(II) complexes of N,N-disubstituted-N′-acylthioureas: Synthesis, structural studies, cytotoxic activity and confocal microscopy studies
  101. Copper(I)–Phosphine Polypyridyl Complexes: Synthesis, Characterization, DNA/HSA Binding Study, and Antiproliferative Activity
  102. Polypyridyl Ruthenium Complexes: Novel DNA-Intercalating Agents against Human Breast Tumor
  103. Half sandwich Ru(ii)-acylthiourea complexes: DNA/HSA-binding, anti-migration and cell death in a human breast tumor cell line
  104. BACE1 levels are increased in plasma of Alzheimer's disease patients compared with matched cognitively healthy controls
  105. Ru(II)/clotrimazole/diphenylphosphine/bipyridine complexes: Interaction with DNA, BSA and biological potential against tumor cell lines and Mycobacterium tuberculosis
  106. Ruthenium(II) complexes of 1,3-thiazolidine-2-thione: Cytotoxicity against tumor cells and anti-Trypanosoma cruzi activity enhanced upon combination with benznidazole
  107. Increase of α-Secretase ADAM10 in Platelets Along Cognitively Healthy Aging
  108. Antioxidant potential of the fruit from Lycium barbarum
  109. Cytotoxicity of Ru(II) piano–stool complexes with chloroquine and chelating ligands against breast and lung tumor cells: Interactions with DNA and BSA
  110. Chiral Platinum(II) Complexes Featuring Phosphine and Chloroquine Ligands as Cytotoxic and Monofunctional DNA-Binding Agents
  111. Serotoninergic antidepressants positively affect platelet ADAM10 expression in patients with Alzheimer's disease
  112. Characterization of metabolic profile of intact non-tumor and tumor breast cells by high-resolution magic angle spinning nuclear magnetic resonance spectroscopy
  113. Molecular Design, Synthesis and Evaluation of 2,3-Diarylquinoxalines as Estrogen Receptor Ligands
  114. Ru(II)-based complexes with N-(acyl)-N′,N′-(disubstituted)thiourea ligands: Synthesis, characterization, BSA- and DNA-binding studies of new cytotoxic agents against lung and prostate tumour cells
  115. Recombinant disintegrin domain of human ADAM9 inhibits migration and invasion of DU145 prostate tumor cells
  116. O5-04-03: Regular multimodal aerobic exercise reduces pro-inflammatory cytokines and improves BDNF peripheral levels and executive functions in elderly MCI individuals with different BDNF Val66Met genotypes
  117. ADAM10 gene expression in the blood cells of Alzheimer's disease patients and mild cognitive impairment subjects
  118. Effects of blocking αvβ3 integrin by a recombinant RGD disintegrin on remodeling of wound healing after induction of incisional hernia in rats
  119. Physical Exercise Improves Peripheral BDNF Levels and Cognitive Functions in Mild Cognitive Impairment Elderly with Different BDNF Val66Met Genotypes
  120. Physical Exercise in MCI Elderly Promotes Reduction of Pro-Inflammatory Cytokines and Improvements on Cognition and BDNF Peripheral Levels
  121. Copper (II) and 2,2′-Bipyridine Complexation Improves Chemopreventive Effects of Naringenin against Breast Tumor Cells
  123. On the cytotoxic activity of Pd(II) complexes of N,N-disubstituted-N′-acyl thioureas
  124. A review of the anticancer effects of a ginger component
  125. Effects of Blocking αvβ3 integrin by a recombinant RGD disintegrin on remodeling of wound healing after induction of incisional hernia in rats
  126. Cedrelone kills breast tumor cells in vitro
  127. Abstract B10: Effects of limonoid cedrelone on MDA-MB-231 breast tumor cells in vitro
  128. Platelet a disintegrin and metallopeptidase 10 expression correlates with clock drawing test scores in Alzheimer's disease
  129. ADAM9 silencing inhibits breast tumor cell invasion in vitro
  130. Correlation Between Mini-Mental State Examination and Platelet ADAM10 Expression in Alzheimer's Disease
  131. ADAM10 as a Biomarker for Alzheimer's Disease: A Study with Brazilian Elderly
  132. Purification and differential biological effects of ginger-derived substances on normal and tumor cell lines
  133. Platelet ADAM10 levels in elderly with mild Alzheimer's disease
  134. Relationship between mini-mental state exam and platelet ADAM10 levels in mild Alzheimer's disease
  135. An Elderly's profile with Alzheimer's disease treated by the exceptional medicine program of São Carlos City (São Paulo, Brazil)
  136. Family functioning and social support for elderly people with cognitive impairments, living in impoverished environments
  137. Familiar functionality in cognitively impaired elderly in a long-term care institution
  138. Rat skin wound healing induced by alternagin-C, a disintegrin-like, Cys-rich protein from Bothrops alternatus venom
  139. The specificity of frutalin lectin using biomembrane models
  140. Camptosemin, a tetrameric lectin of Camptosema ellipticum: structural and functional analysis
  141. Inhibition of platelets and tumor cell adhesion by the disintegrin domain of human ADAM9 to collagen I under dynamic flow conditions
  142. Integrating MR techniques to study Alzheimer's disease
  143. The three-dimensional structure of bothropasin, the main hemorrhagic factor from Bothrops jararaca venom: Insights for a new classification of snake venom metalloprotease subgroups
  144. Effects of alternagin-C from Bothrops alternatus on gene expression and activity of metalloproteinases in regenerating skeletal muscle
  145. Hemostatic effects of recombinant DisBa-01, a disintegrin from Bothrops alternatus
  146. Endocytosis of pulchellin and its recombinant B-chain into K-562 cells: Binding and uptake studies
  147. A novel αvβ3-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis
  148. Modulation of in vitro and in vivo angiogenesis by alternagin-C, a disintegrin-like protein from Bothrops alternatus snake venom and by a peptide derived from its sequence
  149. L'imagerie par bioluminescence pour visualiser la progression tumorale et la métastase chez le petit animal
  150. Alternagin-C, a disintegrin-like protein from the venom of Bothrops alternatus, modulates alpha2ß1 integrin-mediated cell adhesion, migration and proliferation
  151. Alternagin-C, a Disintegrin-like Protein, Induces Vascular Endothelial Cell Growth Factor (VEGF) Expression and Endothelial Cell Proliferation in Vitro
  152. BaG, a new dimeric metalloproteinase/disintegrin from the Bothrops alternatus snake venom that interacts with α5β1 integrin
  153. Characterization and partial purification of a lectin from the hemolymph of the white shrimp Litopenaeus schmitti