All Stories

  1. Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

    Article • Journal of Periodontal Research, July 2025, Wiley

    Deepak Shukla

  2. Different forms of the Akt protein control how the immune system responds to HSV-1 infection

    Article • Proceedings of the National Academy of Sciences, July 2025, Proceedings of the National Academy of Sciences

    Deepak Shukla

  3. HPSE-mediated proinflammatory signaling contributes to neurobehavioral deficits following intranasal HSV-1 infection

    Article • mBio, April 2025, ASM Journals

    Deepak Shukla

  4. Heparanase, a host gene that potently restricts retrovirus transcription

    Article • mBio, April 2025, ASM Journals

    Deepak Shukla

  5. Herpesvirus Infections of the Corneal Endothelium

    Article • Microorganisms, March 2025, MDPI AG

    Deepak Shukla

  6. Heparanase 2 Modulation Inhibits HSV-2 Replication by Regulating Heparan Sulfate

    Article • Viruses, November 2024, MDPI AG

    Deepak Shukla

  7. Co-Expression of Niemann-Pick Type C1-Like1 (NPC1L1) with ACE2 Receptor Synergistically Enhances SARS-CoV-2 Entry and Fusion

    Article • Biomedicines, April 2024, MDPI AG

    Deepak Shukla

  8. Viral MicroRNAs in Herpes Simplex Virus 1 Pathobiology

    Article • Current Pharmaceutical Design, March 2024, Bentham Science Publishers

    Deepak Shukla

  9. OPTN-TBK1 axis and a role for PLK1 in HSV-1 infection

    Article • mBio, December 2023, ASM Journals

    Deepak Shukla

  10. The Interplay of Genital Herpes with Cellular Processes: A Pathogenesis and Therapeutic Perspective

    Article • Viruses, October 2023, MDPI AG

    Deepak Shukla

  11. Tolerability, pharmacokinetics, and anti-herpetic activity of orally administered BX795

    Article • Biomedicine & Pharmacotherapy, September 2023, Elsevier

    Deepak Shukla

  12. Pathophysiology of reinfection by exogenous HSV-1 is driven by heparanase dysfunction

    Article • Science Advances, April 2023, American Association for the Advancement of Science

    Deepak Shukla

  13. Neutrophil Extracellular Traps and Their Possible Implications in Ocular Herpes Infection

    Article • Pathogens, January 2023, MDPI AG

    Deepak Shukla

  14. Archaic connectivity between the sulfated heparan sulfate and the herpesviruses – An evolutionary potential for cross-species interactions

    Article • Computational and Structural Biotechnology Journal, January 2023, Elsevier

    Deepak Shukla

  15. Putative targeting by BX795 causes decrease in protein kinase C protein levels and inhibition of HSV1 infection

    Article • Antiviral Research, December 2022, Elsevier

    Deepak Shukla

  16. Topical phenylbutyrate antagonizes NF-κB signaling and resolves corneal inflammation

    Article • iScience, December 2022, Elsevier

    Deepak Shukla

  17. Postinfection Metabolic Reprogramming of the Murine Trigeminal Ganglion Limits Herpes Simplex Virus-1 Replication

    Article • mBio, October 2022, ASM Journals

    Deepak Shukla

  18. Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected Cells

    Article • Viruses, September 2022, MDPI AG

    Deepak Shukla

  19. Immune Response to SARS-CoV-2 Vaccines

    Article • Biomedicines, June 2022, MDPI AG

    Deepak Shukla

  20. Optineurin in ocular herpes infection

    Article • Experimental Eye Research, June 2022, Elsevier

    Deepak Shukla

  21. CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells

    Article • Viruses, May 2022, MDPI AG

    Deepak Shukla

  22. Plasma Membrane-Derived Liposomes Exhibit Robust Antiviral Activity against HSV-1

    Article • Viruses, April 2022, MDPI AG

    Deepak Shukla

  23. OPTN (optineurin)-mediated selective autophagy prevents neurodegeneration due to herpesvirus infection

    Article • Autophagy, February 2022, Taylor & Francis

    Deepak Shukla

  24. Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection

    Article • The Journal of Immunology, January 2022, Oxford University Press (OUP)

    Deepak Shukla

  25. Heparanase-Induced Activation of AKT Stabilizes β-Catenin and Modulates Wnt/β-Catenin Signaling during Herpes Simplex Virus 1 Infection

    Article • mBio, December 2021, ASM Journals

    Deepak Shukla

  26. BX795-Organic Acid Coevaporates: Evaluation of Solid-State Characteristics, In Vitro Cytocompatibility and In Vitro Activity against HSV-1 and HSV-2

    Article • Pharmaceutics, November 2021, MDPI AG

    Deepak Shukla

  27. mTORC2 confers neuroprotection and potentiates immunity during virus infection

    Article • Nature Communications, October 2021, Springer Science + Business Media

    Deepak Shukla

  28. Aptamers in Virology—A Consolidated Review of the Most Recent Advancements in Diagnosis and Therapy

    Article • Pharmaceutics, October 2021, MDPI AG

    Deepak Shukla

  29. Prophylactic treatment with BX795 blocks activation of AKT and its downstream targets to protect vaginal keratinocytes and vaginal epithelium from HSV-2 infection

    Article • Antiviral Research, October 2021, Elsevier

    Deepak Shukla

  30. OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection

    Article • Nature Communications, September 2021, Springer Science + Business Media

    Deepak Shukla

  31. Protease, Growth Factor, and Heparanase-Mediated Syndecan-1 Shedding Leads to Enhanced HSV-1 Egress

    Article • Viruses, September 2021, MDPI AG

    Deepak Shukla

  32. Histatin-1 Attenuates LPS-Induced Inflammatory Signaling in RAW264.7 Macrophages

    Article • International Journal of Molecular Sciences, July 2021, MDPI AG

    Deepak Shukla

  33. Heparan Sulfate Binding Cationic Peptides Restrict SARS-CoV-2 Entry

    Article • Pathogens, June 2021, MDPI AG

    Deepak Shukla

  34. The 3- O -sulfation of heparan sulfate modulates protein binding and lyase degradation

    Article • Proceedings of the National Academy of Sciences, January 2021, Proceedings of the National Academy of Sciences

    Deepak Shukla

  35. Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing

    Article • Science Advances, December 2020, American Association for the Advancement of Science

    Deepak Shukla

  36. In Vitro and In Vivo Activity, Tolerability, and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus 2 Genital Infection

    Article • Antimicrobial Agents and Chemotherapy, August 2020, ASM Journals

    Deepak Shukla

  37. Vaccines and Therapies in Development for SARS-CoV-2 Infections

    Article • Journal of Clinical Medicine, June 2020, MDPI AG

    Deepak Shukla

  38. Heparanase, cell signaling, and viral infections

    Article • Cellular and Molecular Life Sciences, May 2020, Springer Science + Business Media

    Deepak Shukla

  39. Current and Emerging Therapies for Ocular Herpes Simplex Virus Type-1 Infections

    Article • Microorganisms, October 2019, MDPI AG

    Deepak Shukla

  40. Drug-encapsulated carbon (DECON): A novel platform for enhanced drug delivery

    Article • Science Advances, August 2019, American Association for the Advancement of Science

    Deepak Shukla

  41. Pathological processes activated by herpes simplex virus-1 (HSV-1) infection in the cornea

    Article • Cellular and Molecular Life Sciences, October 2018, Springer Science + Business Media

    Deepak Shukla

  42. Host Enzymes Heparanase and Cathepsin L Promote Herpes Simplex Virus 2 Release from Cells

    Article • Journal of Virology, September 2018, ASM Journals

    Deepak Shukla

  43. An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye

    Article • Science Translational Medicine, February 2018, American Association for the Advancement of Science

    Deepak Shukla

  44. Emerging Roles of Heparanase in Viral Pathogenesis

    Article • Pathogens, September 2017, MDPI AG

    Deepak Shukla

  45. Viral Activation of Heparanase Drives Pathogenesis of Herpes Simplex Virus-1

    Article • Cell Reports, July 2017, Elsevier

    Deepak Shukla

  46. Effects of histatin-1 peptide on human corneal epithelial cells

    Article • PLOS One, May 2017, PLOS

    Deepak Shukla

  47. Cultured corneas show dendritic spread and restrict herpes simplex virus infection that is not observed with cultured corneal cells

    Article • Scientific Reports, February 2017, Springer Science + Business Media

    Deepak Shukla

  48. Role of metal and metal oxide nanoparticles as diagnostic and therapeutic tools for highly prevalent viral infections

    Article • Nanomedicine Nanotechnology Biology and Medicine, January 2017, Elsevier

    Deepak Shukla

  49. Could Zinc Oxide Tetrapod Nanoparticles Be Used as an Effective Immunotherapy Against HSV-2?

    Article • Nanomedicine, August 2016, Taylor & Francis

    Deepak Shukla

  50. Liposome-Mediated Herpes Simplex Virus Uptake Is Glycoprotein-D Receptor-Independent but Requires Heparan Sulfate

    Article • Frontiers in Microbiology, June 2016, Frontiers

    Deepak Shukla

  51. Intravaginal Zinc Oxide Tetrapod Nanoparticles as Novel Immunoprotective Agents against Genital Herpes

    Article • The Journal of Immunology, April 2016, The American Association of Immunologists

    PD Dr. habil. Yogendra Kumar Mishra, Deepak Shukla

  52. Filopodia and Viruses: An Analysis of Membrane Processes in Entry Mechanisms

    Article • Frontiers in Microbiology, March 2016, Frontiers

    Deepak Shukla

  53. Extended Release of an Anti–Heparan Sulfate Peptide From a Contact Lens Suppresses Corneal Herpes Simplex Virus-1 Infection

    Article • Investigative Ophthalmology & Visual Science, January 2016, Association for Research in Vision and Ophthalmology (ARVO)

    Deepak Shukla

  54. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang, Professor George Perry, Professor Godefridus J Peters, Shuo-Chien Ling, Professor Jiwu Wei, Deepak Shukla

  55. Cell Entry Mechanisms of HSV: What we have Learned in Recent Years

    Article • Future Virology, October 2015, Taylor & Francis

    Deepak Shukla

  56. Long-Term Outcomes and Prognostic Factors of Trabeculectomy following Intraocular Bevacizumab Injection for Neovascular Glaucoma

    Article • PLOS One, August 2015, PLOS

    Deepak Shukla

  57. Basal Autophagy Is Required for Herpes simplex Virus-2 Infection

    Article • Scientific Reports, August 2015, Springer Science + Business Media

    Deepak Shukla

  58. Heparanase is a host enzyme required for herpes simplex virus-1 release from cells

    Article • Nature Communications, April 2015, Springer Science + Business Media

    Deepak Shukla

  59. Herpes Simplex Virus-1 Fine-Tunes Host’s Autophagic Response to Infection: A Comprehensive Analysis in Productive Infection Models

    Article • PLOS One, April 2015, PLOS

    Deepak Shukla

  60. Autophagy Stimulation Abrogates Herpes simplex Virus-1 Infection

    Article • Scientific Reports, April 2015, Springer Science + Business Media

    Deepak Shukla

  61. A Role for 3-O-Sulfated Heparan Sulfate in Promoting Human Cytomegalovirus Infection in Human Iris Cells

    Article • Journal of Virology, February 2015, ASM Journals

    Deepak Shukla

  62. Semaphorin 7a in Herpetic Neurotrophic Keratitis

    Article • Investigative Ophthalmology & Visual Science, February 2015, Association for Research in Vision and Ophthalmology (ARVO)

    Deepak Shukla

  63. Diversity of Heparan Sulfate and HSV Entry: Basic Understanding and Treatment Strategies

    Article • Molecules, February 2015, MDPI AG

    Deepak Shukla

  64. Corneal lymphangiogenesis in herpetic stromal keratitis

    Article • Survey of Ophthalmology, January 2015, Elsevier

    Deepak Shukla

  65. Characterization of a Proteolytically Stable D-Peptide That Suppresses Herpes Simplex Virus 1 Infection: Implications for the Development of Entry-Based Antiviral Therapy

    Article • Journal of Virology, November 2014, ASM Journals

    Deepak Shukla

  66. Comprehensive Analysis of Herpes Simplex Virus 1 (HSV-1) Entry Mediated by Zebrafish 3-O-Sulfotransferase Isoforms: Implications for the Development of a Zebrafish Model of HSV-1 Infection

    Article • Journal of Virology, August 2014, ASM Journals

    Deepak Shukla

  67. Zebrafish 3-O-Sulfotransferase-4 Generated Heparan Sulfate Mediates HSV-1 Entry and Spread

    Article • PLOS One, February 2014, PLOS

    Deepak Shukla

  68. Zebrafish: Modeling for Herpes Simplex Virus Infections

    Article • Zebrafish, February 2014, Mary Ann Liebert Inc

    Deepak Shukla

  69. Inhibition of Myosin Light Chain Kinase Can be Targeted for the Development of New Therapies against Herpes Simplex Virus Type-1 Infection

    Article • Antiviral Therapy, January 2014, SAGE Publications

    Deepak Shukla

  70. An Investigative Peptide–Acyclovir Combination to Control Herpes Simplex Virus Type 1 Ocular Infection

    Article • Investigative Ophthalmology & Visual Science, September 2013, Association for Research in Vision and Ophthalmology (ARVO)

    Deepak Shukla

  71. Exploiting Herpes Simplex Virus Entry for Novel Therapeutics

    Article • Viruses, June 2013, MDPI AG

    Deepak Shukla

  72. Authors' Response

    Article • Survey of Ophthalmology, May 2013, Elsevier

    Deepak Shukla

  73. Role of heparan sulfate in ocular diseases

    Article • Experimental Eye Research, May 2013, Elsevier

    Deepak Shukla

  74. Recent advances in vaccine development for herpes simplex virus types I and II

    Article • Human Vaccines & Immunotherapeutics, April 2013, Taylor & Francis

    Deepak Shukla

  75. Zebrafish encoded 3-O-sulfotransferase-2 generated heparan sulfate serves as a receptor during HSV-1 entry and spread

    Article • Biochemical and Biophysical Research Communications, March 2013, Elsevier

    Deepak Shukla

  76. Glycoprotein targeted therapeutics: a new era of anti‐herpes simplex virus‐1 therapeutics

    Article • Reviews in Medical Virology, February 2013, Wiley

    Deepak Shukla

  77. Susceptibility of Human Iris Stromal Cells to Herpes Simplex Virus 1 Entry

    Article • Journal of Virology, January 2013, ASM Journals

    Deepak Shukla

  78. Prophylactic, therapeutic and neutralizing effects of zinc oxide tetrapod structures against herpes simplex virus type-2 infection

    Article • Antiviral Research, December 2012, Elsevier

    PD Dr. habil. Yogendra Kumar Mishra, Deepak Shukla

  79. Tin Oxide Nanowires Suppress Herpes Simplex Virus-1 Entry and Cell-to-Cell Membrane Fusion

    Article • PLOS One, October 2012, PLOS

    PD Dr. habil. Yogendra Kumar Mishra, Deepak Shukla

  80. Contortrostatin, a Homodimeric Disintegrin Isolated from Snake Venom Inhibits Herpes Simplex Virus Entry and Cell Fusion

    Article • Antiviral Therapy, October 2012, SAGE Publications

    Deepak Shukla

  81. Herpes Simplex Epithelial and Stromal Keratitis: An Epidemiologic Update

    Article • Survey of Ophthalmology, September 2012, Elsevier

    Deepak Shukla

  82. Role of heparan sulfate in sexually transmitted infections

    Article • Glycobiology, July 2012, Oxford University Press (OUP)

    Deepak Shukla

  83. Unraveling the Cell Entry Mechanisms of HSV: Therapeutic Potential?

    Article • Future Virology, May 2012, Taylor & Francis

    Deepak Shukla

  84. A 3-O-Sulfated Heparan Sulfate Binding Peptide Preferentially Targets Herpes Simplex Virus 2-Infected Cells

    Article • Journal of Virology, April 2012, ASM Journals

    Deepak Shukla

  85. Increased axonal expression of nectin-1 in multiple sclerosis plaques

    Article • Neurological Sciences, March 2012, Springer Science + Business Media

    Deepak Shukla

  86. Early Events in Herpes Simplex Virus Lifecycle with Implications for an Infection of Lifetime

    Article • The Open Virology Journal, January 2012, Bentham Science Publishers

    Deepak Shukla

  87. Nonprofessional Phagocytosis Can Facilitate Herpesvirus Entry into Ocular Cells

    Article • Clinical and Developmental Immunology, January 2012, Wiley

    Deepak Shukla

  88. Virostatic potential of micro–nano filopodia-like ZnO structures against herpes simplex virus-1

    Article • Antiviral Research, November 2011, Elsevier

    PD Dr. habil. Yogendra Kumar Mishra, Deepak Shukla

  89. Herpes simplex virus infects most cell types in vitro: clues to its success

    Article • Virology Journal, October 2011, Springer Science + Business Media

    Deepak Shukla

  90. An Important Role for Syndecan-1 in Herpes Simplex Virus Type-1 Induced Cell-to-Cell Fusion and Virus Spread

    Article • PLOS One, September 2011, PLOS

    Deepak Shukla

  91. Anti-heparan Sulfate Peptides That Block Herpes Simplex Virus Infection in Vivo

    Article • Journal of Biological Chemistry, July 2011, Elsevier

    Deepak Shukla

  92. Chronic Progressive Deficits in Neuron Size, Density and Number in the Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus

    Article • Brain Pathology, April 2011, Wiley

    Deepak Shukla

  93. Corneal Latency and Transmission of Herpes Simplex Virus-1

    Article • Future Virology, December 2010, Taylor & Francis

    Deepak Shukla

  94. Syndecan-1 and syndecan-2 play key roles in herpes simplex virus type-1 infection

    Article • Journal of General Virology, December 2010, Society for General Microbiology

    Deepak Shukla

  95. The role of herpesviruses in ocular infections

    Article • Virus Adaptation and Treatment, September 2010, Taylor & Francis

    Deepak Shukla

  96. Phosphoinositide 3 kinase signalling may affect multiple steps during herpes simplex virus type-1 entry

    Article • Journal of General Virology, September 2010, Society for General Microbiology

    Deepak Shukla

  97. In vitro antiviral activity of neem (Azardirachta indica L.) bark extract against herpes simplex virus type‐1 infection

    Article • Phytotherapy Research, July 2010, Wiley

    Deepak Shukla

  98. Mediators and Mechanisms of Herpes Simplex Virus Entry into Ocular Cells

    Article • Current Eye Research, May 2010, Taylor & Francis

    Deepak Shukla

  99. Expanding the role of 3-O sulfated heparan sulfate in herpes simplex virus type-1 entry

    Article • Virology, February 2010, Elsevier

    Deepak Shukla

  100. A role for heparan sulfate in viral surfing

    Article • Biochemical and Biophysical Research Communications, January 2010, Elsevier

    Deepak Shukla

  101. An unusual dependence of human herpesvirus-8 glycoproteins-induced cell-to-cell fusion on heparan sulfate

    Article • Biochemical and Biophysical Research Communications, December 2009, Elsevier

    Deepak Shukla

  102. Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry

    Article • European Journal of Biochemistry, November 2009, Wiley

    Deepak Shukla

  103. Viral entry mechanisms: simplicity drives complexity

    Article • European Journal of Biochemistry, November 2009, Wiley

    Deepak Shukla

  104. Identification of virus resistant tumor cell subpopulations in three-dimensional uveal melanoma cultures

    Article • Cancer Gene Therapy, November 2009, Springer Science + Business Media

    Deepak Shukla

  105. INTRAVITREAL ALEMTUZUMAB PENETRATES FULL-THICKNESS RETINA IN RABBIT EYES

    Article • Retina, November 2009, Wolters Kluwer Health

    Deepak Shukla

  106. A Novel Function of Heparan Sulfate in the Regulation of Cell-Cell Fusion

    Article • Journal of Biological Chemistry, October 2009, Elsevier

    Deepak Shukla

  107. A sugar binding protein cyanovirin-N blocks herpes simplex virus type-1 entry and cell fusion

    Article • Antiviral Research, October 2009, Elsevier

    Deepak Shukla

  108. Expression of Herpes Virus Entry Mediator (HVEM) in the Cornea and Trigeminal Ganglia of Normal and HSV-1 Infected Mice

    Article • Current Eye Research, October 2009, Taylor & Francis

    Deepak Shukla

  109. Role of Nectin-1, HVEM, and PILR-α in HSV-2 Entry into Human Retinal Pigment Epithelial Cells

    Article • Investigative Ophthalmology & Visual Science, June 2009, Association for Research in Vision and Ophthalmology (ARVO)

    Deepak Shukla

  110. The importance of heparan sulfate in herpesvirus infection

    Article • Virologica Sinica, December 2008, Elsevier

    Deepak Shukla

  111. Role for nectin‐1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells

    Article • European Journal of Biochemistry, October 2008, Wiley

    Deepak Shukla

  112. Antiviral Activity of Phytochemicals: A Comprehensive Review

    Article • Mini-Reviews in Medicinal Chemistry, October 2008, Bentham Science Publishers

    Deepak Shukla

  113. HVEM and Nectin-1 Are the Major Mediators of Herpes Simplex Virus 1 (HSV-1) Entry into Human Conjunctival Epithelium

    Article • Investigative Ophthalmology & Visual Science, September 2008, Association for Research in Vision and Ophthalmology (ARVO)

    Deepak Shukla

  114. Herpes simplex virus type 1 induces filopodia in differentiated P19 neural cells to facilitate viral spread

    Article • Neuroscience Letters, August 2008, Elsevier

    Deepak Shukla

  115. Using a 3-O-Sulfated Heparin Octasaccharide To Inhibit the Entry of Herpes Simplex Virus Type 1

    Article • Biochemistry, May 2008, American Chemical Society (ACS)

    Deepak Shukla

  116. Nectin-1 (HveC) is expressed at high levels in neural subtypes that regulate radial migration of cortical and cerebellar neurons of the developing human and murine brain

    Article • Journal of NeuroVirology, January 2008, Springer Science + Business Media

    Deepak Shukla

  117. RITUXIMAB PENETRATES FULL-THICKNESS RETINA IN CONTRAST TO TISSUE PLASMINOGEN ACTIVATOR CONTROL

    Article • Retina, October 2007, Wolters Kluwer Health

    Deepak Shukla

  118. Role of 3‐O‐sulfated heparan sulfate in virus‐induced polykaryocyte formation

    Article • FEBS Letters, August 2007, Wiley

    Deepak Shukla

  119. Herpes simplex virus type 2 entry into cultured human corneal fibroblasts is mediated by herpesvirus entry mediator

    Article • Journal of General Virology, August 2007, Society for General Microbiology

    Deepak Shukla

  120. Viral Inhibition Studies on Sulfated Lignin, a Chemically Modified Biopolymer and a Potential Mimic of Heparan Sulfate

    Article • Biomacromolecules, April 2007, American Chemical Society (ACS)

    Deepak Shukla

  121. Soluble 3-O-sulfated heparan sulfate can trigger herpes simplex virus type 1 entry into resistant Chinese hamster ovary (CHO-K1) cells

    Article • Journal of General Virology, April 2007, Society for General Microbiology

    Deepak Shukla

  122. Herpes simplex virus type 1 infection induces oxidative stress and the release of bioactive lipid peroxidation by-products in mouse P19N neural cell cultures

    Article • Journal of NeuroVirology, January 2007, Springer Science + Business Media

    Deepak Shukla

  123. A novel role for phagocytosis-like uptake in herpes simplex virus entry

    Article • Journal of Cell Biology, September 2006, Rockefeller University Press

    Deepak Shukla

  124. Role for 3-O-Sulfated Heparan Sulfate as the Receptor for Herpes Simplex Virus Type 1 Entry into Primary Human Corneal Fibroblasts

    Article • Journal of Virology, September 2006, ASM Journals

    Deepak Shukla

  125. Expression of Nectin-1 in Normal and Herpes Simplex Virus Type 1-Infected Murine Brain

    Article • Applied Immunohistochemistry & Molecular Morphology, September 2006, Wolters Kluwer Health

    Deepak Shukla

  126. A role for heparan sulfate 3-O-sulfotransferase isoform 2 in herpes simplex virus type 1 entry and spread

    Article • Virology, March 2006, Elsevier

    Deepak Shukla

  127. A role for 3-O-sulfotransferase isoform-4 in assisting HSV-1 entry and spread

    Article • Biochemical and Biophysical Research Communications, December 2005, Elsevier

    Deepak Shukla

  128. A Role for Herpesvirus Entry Mediator as the Receptor for Herpes Simplex Virus 1 Entry into Primary Human Trabecular Meshwork Cells

    Article • Journal of Virology, October 2005, ASM Journals

    Deepak Shukla

  129. Spinoculation of heparan sulfate deficient cells enhances HSV-1 entry, but does not abolish the need for essential glycoproteins in viral fusion

    Article • Journal of Virological Methods, September 2005, Elsevier

    Deepak Shukla

  130. Structural Characterization of a Serendipitously Discovered Bioactive Macromolecule, Lignin Sulfate

    Article • Biomacromolecules, July 2005, American Chemical Society (ACS)

    Deepak Shukla

  131. Characterization of heparan sulphate 3-O-sulphotransferase isoform 6 and its role in assisting the entry of herpes simplex virus type 1

    Article • Biochemical Journal, January 2005, Portland Press Ltd.

    Deepak Shukla

  132. Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase

    Article • Journal of Cell Biology, September 2004, Rockefeller University Press

    Deepak Shukla

  133. A role for 3-O-sulfated heparan sulfate in cell fusion induced by herpes simplex virus type 1

    Article • Journal of General Virology, April 2004, Society for General Microbiology

    Deepak Shukla

  134. Herpes simplex virus entry receptor nectin-1 is widely expressed in the murine eye

    Article • Current Eye Research, January 2004, Taylor & Francis

    Deepak Shukla

  135. Mutations in the N Termini of Herpes Simplex Virus Type 1 and 2 gDs Alter Functional Interactions with the Entry/Fusion Receptors HVEM, Nectin-2, and 3-O-Sulfated Heparan Sulfate but Not with Nectin-1

    Article • Journal of Virology, September 2003, ASM Journals

    Deepak Shukla

  136. Cellular expression of gH confers resistance to herpes simplex virus type-1 entry

    Article • Virology, July 2003, Elsevier

    Deepak Shukla

  137. Heparan Sulfate 3-O-Sulfotransferase Isoform 5 Generates Both an Antithrombin-binding Site and an Entry Receptor for Herpes Simplex Virus, Type 1

    Article • Journal of Biological Chemistry, October 2002, Elsevier

    Deepak Shukla

  138. Portable sulphotransferase domain determines sequence specificity of heparan sulphate 3-O-sulphotransferases

    Article • Biochemical Journal, September 2001, Portland Press Ltd.

    Deepak Shukla

  139. Transcription from the Gene Encoding the Herpesvirus Entry Receptor Nectin-1 (HveC) in Nervous Tissue of Adult Mouse

    Article • Virology, September 2001, Elsevier

    Deepak Shukla

  140. Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry

    Article • Journal of Clinical Investigation, August 2001, American Society for Clinical Investigation

    Deepak Shukla

  141. Striking Similarity of Murine Nectin-1α to Human Nectin-1α (HveC) in Sequence and Activity as a Glycoprotein D Receptor for Alphaherpesvirus Entry

    Article • Journal of Virology, December 2000, ASM Journals

    Deepak Shukla

  142. A Novel Role for 3-O-Sulfated Heparan Sulfate in Herpes Simplex Virus 1 Entry

    Article • Cell, October 1999, Elsevier

    Deepak Shukla

  143. Flagellar Motor-switch Binding Face of CheY and the Biochemical Basis of Suppression by CheY Mutants That Compensate for Motor-switch Defects in Escherichia coli

    Article • Journal of Biological Chemistry, September 1998, Elsevier

    Deepak Shukla

  144. Mutations Leading to Altered CheA Binding Cluster on a Face of CheY

    Article • Journal of Biological Chemistry, October 1995, Elsevier

    Deepak Shukla