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  1. Sex-based Immune and Genetic Mechanisms in Asthma: A Shift Toward Precision Medicine?

    Article • American Journal of Respiratory Cell and Molecular Biology, October 2025, American Thoracic Society

    Dr Pawan Sharma

  2. E3 Ligase RNF145 Regulates Airway Smooth Muscle Cell Growth Through PP2A Mediated Regulation of p70S6 Kinase

    Article • American Review of Respiratory Disease, May 2025, American Thoracic Society

    Dr Pawan Sharma

  3. Prenatal exposure to air pollution affects autophagy, senescence, and remodelling proteins in cord blood

    Article • ERJ Open Research, April 2025, European Respiratory Society (ERS)

    Dr Pawan Sharma

  4. Differences in autophagy marker levels at birth in preterm vs. term infants

    Article • Pediatric Research, May 2024, Springer Science + Business Media

    Dr Pawan Sharma

  5. Role of Novel E3 Ubiquitin Ligase RNF145 in Airway Smooth Muscle Growth and Lung Function

    Article • April 2024, American Thoracic Society

    Dr Pawan Sharma

  6. Heated tobacco product IQOS induces unique metabolic signatures in human bronchial epithelial cells

    Article • ERJ Open Research, December 2023, European Respiratory Society (ERS)

    Dr Pawan Sharma

  7. Late Breaking Abstract - Differences in autophagy marker levels at birth in preterm vs. term infants

    Article • September 2023, European Respiratory Society (ERS)

    Dr Pawan Sharma

  8. Late Breaking Abstract - Prenatal exposure to air pollution affects newborns’ autophagy, senescence and remodelling proteins

    Article • September 2023, European Respiratory Society (ERS)

    Dr Pawan Sharma

  9. Ambient particulate matter (PM2.5) exposure contributes to neurodegeneration through the microbiome-gut-brain axis: Therapeutic role of melatonin

    Article • Environmental Toxicology and Pharmacology, August 2023, Elsevier

    Dr Pawan Sharma

  10. Molecular Determinants, Clinical Manifestations and Effects of Immunization on Cardiovascular Health During COVID-19 Pandemic Era - A Review

    Article • Current Problems in Cardiology, August 2023, Elsevier

    Dr Pawan Sharma

  11. Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis

    Article • Clinical Science, May 2023, Portland Press Ltd.

    Dr Pawan Sharma

  12. The effects of dual IQOS and cigarette smoke exposure on airway epithelial cells: implications for lung health and respiratory disease pathogenesis

    Article • ERJ Open Research, February 2023, European Respiratory Society (ERS)

    Dr Pawan Sharma

  13. Targeted Inhibition of Select Extracellular Signal-regulated Kinases 1 and 2 Functions Mitigates Pathological Features of Asthma in Mice

    Article • American Journal of Respiratory Cell and Molecular Biology, January 2023, American Thoracic Society

    Dr Pawan Sharma

  14. Piperine Attenuates Cigarette Smoke-Induced Oxidative Stress, Lung Inflammation, and Epithelial–Mesenchymal Transition by Modulating the SIRT1/Nrf2 Axis

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Dr Pawan Sharma

  15. Diversity, equity and inclusion in autophagy research

    Article • Autophagy, November 2022, Taylor & Francis

    Dr Pawan Sharma

  16. Effects of intranasal azithromycin on features of cigarette smoke-induced lung inflammation

    Article • European Journal of Pharmacology, January 2022, Elsevier

    Dr Pawan Sharma

  17. Diacylglycerol Kinase Inhibition Reduces Airway Contraction by Negative Feedback Regulation of Gq-Signaling

    Article • American Journal of Respiratory Cell and Molecular Biology, December 2021, American Thoracic Society

    Dr Pawan Sharma

  18. Autocrine regulation of airway smooth muscle contraction by diacylglycerol kinase

    Article • Journal of Cellular Physiology, July 2021, Wiley

    Dr Pawan Sharma

  19. Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis

    Article • Cells, June 2021, MDPI AG

    Dr Pawan Sharma

  20. Emerging Advances of Nanotechnology in Drug and Vaccine Delivery against Viral Associated Respiratory Infectious Diseases (VARID)

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Dr Pawan Sharma

  21. Sex Differences in the Induction of Angiotensin Converting Enzyme 2 (Ace-2) in Mouse Lungs after E-Cigarette Vapor Exposure and Its Relevance to Covid-19

    Article • Journal of Investigative Medicine, June 2021, SAGE Publications

    Dr Pawan Sharma

  22. Chloroquine: Autophagy inhibitor, antimalarial, bitter taste receptor agonist in fight against COVID-19, a reality check?

    Article • European Journal of Pharmacology, April 2021, Elsevier

    Dr Pawan Sharma

  23. Hispolon inhibits RANKL induced osteoclast differentiation in vitro

    Article • Immunology Letters, March 2021, Elsevier

    Dr Pawan Sharma

  24. Statins in patients with COVID-19: a retrospective cohort study in Iranian COVID-19 patients

    Article • Translational Medicine Communications, January 2021, Springer Science + Business Media

    Dr Katarzyna L Kotfis, Dr Pawan Sharma

  25. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Article • Autophagy, January 2021, Taylor & Francis

    MD, PhD Pierre-Louis Tharaux, Joilson O. Martins, Dr. rer. nat. Marc Herb, Dr Marcia R Cominetti, Alessio Di Fonzo, Christoph Gerhardt, Dr Mustafa Sahin, Dr Cinzia Volonté, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Prof Robert Bryson-Richardson, Professor Hyun Kyu Song, Prof Claudia Cavadas, Professor Po Sing Leung, Paula Ludovico, Javeed Shah, Prof. Dr. Giovanni Di Guardo, Dr Takeshi Noda, Professor Tullio Florio, Professor Kevin Coombs, Ning Chen, Maria Vaccaro, Dr Jorge F Quarleri, Professor hengyi xiao, Dr. Yanzhuang Wang, Prof Giacinto Bagetta, Dr. Ann M Wehman, Dr Pawan Sharma, Dr Anna Krasnodembskaya, Dr Francesca Finetti, Nicoletta Filigheddu, Professor Javier González-Gallego, Professor Günther Weindl

  26. Mechanisms Targeting the Unfolded Protein Response in Asthma

    Article • American Journal of Respiratory Cell and Molecular Biology, January 2021, American Thoracic Society

    Dr Pawan Sharma

  27. Can GPCRs Be Targeted to Control Inflammation in Asthma?

    Article • January 2021, Springer Science + Business Media

    Dr Pawan Sharma

  28. The ER Stress/UPR Axis in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

    Article • Life, December 2020, MDPI AG

    Dr Pawan Sharma

  29. Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells

    Article • Cells, October 2020, MDPI AG

    Dr Pawan Sharma

  30. Does Vaping Increase Susceptibility to COVID-19?

    Article • American Review of Respiratory Disease, October 2020, American Thoracic Society

    Dr Pawan Sharma

  31. Reply to Sharma and Zeki: Does Vaping Increase Susceptibility to COVID-19?

    Article • American Review of Respiratory Disease, October 2020, American Thoracic Society

    Dr Pawan Sharma

  32. The rise of electronic nicotine delivery systems and the emergence of electronic-cigarette-driven disease

    Article • AJP Lung Cellular and Molecular Physiology, October 2020, American Physiological Society

    Dr Pawan Sharma

  33. The Ill Effects of IQOS on Airway Cells: Let’s Not Get Burned All Over Again

    Article • American Journal of Respiratory Cell and Molecular Biology, August 2020, American Thoracic Society

    Dr Pawan Sharma

  34. Pharmacologic Inhibition of Vacuolar H+ATPase Attenuates Features of Severe Asthma in Mice

    Article • American Journal of Respiratory Cell and Molecular Biology, January 2020, American Thoracic Society

    Dr Pawan Sharma

  35. Altered Calcium in Ciliary Dysfunction: Potential Role of Endoplasmic Reticulum Stress and Ciliophagy

    Article • American Journal of Respiratory Cell and Molecular Biology, December 2019, American Thoracic Society

    Dr Pawan Sharma

  36. Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition

    Article • European Journal of Pharmacology, November 2019, Elsevier

    Dr Pawan Sharma

  37. Mitochondrial dysfunction in macrophages: a key to defective bacterial phagocytosis in COPD

    Article • European Respiratory Journal, October 2019, European Respiratory Society (ERS)

    Dr Sukhwinder Singh Sohal, Dr Pawan Sharma

  38. Inhaled corticosteroids attenuate epithelial mesenchymal transition: implications for COPD and lung cancer prophylaxis

    Article • European Respiratory Journal, July 2019, European Respiratory Society (ERS)

    Dr Sukhwinder Singh Sohal, Dr Pawan Sharma

  39. Epithelial–mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics

    Article • International Journal of Chronic Obstructive Pulmonary Disease, July 2019, Dove Medical Press

    Mathew Eapen, Dr Pawan Sharma, Phil Hansbro, Archana Gaikwad

  40. There can be smoke without fire: warranted caution in promoting electronic cigarettes and heat not burn devices as a safer alternative to cigarette smoking

    Article • ERJ Open Research, July 2019, European Respiratory Society (ERS)

    Dr Pawan Sharma

  41. New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways

    Article • Clinical Science, July 2019, Portland Press Ltd.

    Dr Pawan Sharma

  42. Autophagy, a potential new target in asthma

    Article • American Journal of Respiratory Cell and Molecular Biology, May 2019, American Thoracic Society

    Dr Pawan Sharma, Dr Sukhwinder Singh Sohal

  43. The effectiveness of immunosuppressive cyclosporin in attenuating the progression of interstitial lung diseases

    Article • Journal of Thoracic Disease, May 2019, AME Publishing Company

    Dr Pawan Sharma

  44. High Fat Diet in Conjunction with Electronic Cigarette Vaping Worsens Lung Function and Inflammation

    Article • May 2019, American Thoracic Society

    Dr Pawan Sharma

  45. IOQS (heat not burn) negatively impacts lung health.

    Article • ERJ Open Research, February 2019, European Respiratory Society (ERS)

    Dr Pawan Sharma

  46. Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies

    Article • Laboratory Investigation, February 2019, Elsevier

    Dr Pawan Sharma

  47. Impact of Maternal Air Pollution Exposure on Children’s Lung Health: An Indian Perspective

    Article • Toxics, November 2018, MDPI AG

    Dr Pawan Sharma

  48. Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities

    Article • Drugs, November 2018, Springer Science + Business Media

    Dr Pawan Sharma

  49. Dysfunctional Immunity and Microbial Adhesion Molecules in Smoking-Induced Pneumonia

    Article • American Review of Respiratory Disease, October 2018, American Thoracic Society

    Dr Pawan Sharma

  50. Steroid insensitive fixed airflow obstruction is not related to airway inflammation in older non-smokers with asthma

    Article • September 2018, Springer Science + Business Media

    Dr Pawan Sharma

  51. Selective activation and targeting of autophagy in severe asthma

    Article • September 2018, European Respiratory Society (ERS)

    Dr Pawan Sharma

  52. Impact of Maternal Air Pollution Exposure on Children’s Lung Health: An Indian Perspective

    Article • September 2018, MDPI AG

    Dr Pawan Sharma

  53. Impact of Maternal Air Pollution Exposure on Children’s Lung Health: An Indian Perspective

    Article • August 2018, MDPI AG

    Dr Pawan Sharma

  54. Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease

    Article • Clinical Science, July 2018, Portland Press Ltd.

    Dr Pawan Sharma

  55. sE-cadherin and sVE-cadherin indicate active epithelial/endothelial to mesenchymal transition (EMT and EndoMT) in smokers and COPD: implications for new biomarkers and therapeutics

    Article • Biomarkers, June 2018, Taylor & Francis

    Dr Pawan Sharma

  56. Autophagy and airway fibrosis: Is there a link?

    Article • F1000Research, June 2018, Faculty of 1000, Ltd.

    Dr Pawan Sharma

  57. Maternal E-Cigarette Exposure in Mice Alters DNA Methylation and Lung Cytokine Expression in Offspring

    Article • American Journal of Respiratory Cell and Molecular Biology, March 2018, American Thoracic Society

    Brian Oliver, Dr Pawan Sharma

  58. A circadian based inflammatory response – implications for respiratory disease and treatment

    Article • Sleep Science and Practice, September 2017, Springer Science + Business Media

    Dr Pawan Sharma

  59. Maternal eCigarette vaping enhances Th2 driven asthma in the offspring

    Article • September 2017, European Respiratory Society (ERS)

    Dr Pawan Sharma

  60. Effect of long-term maternal smoking on the offspring’s lung health

    Article • AJP Lung Cellular and Molecular Physiology, August 2017, American Physiological Society

    Dr Pawan Sharma, Brian Oliver

  61. Bitter taste receptor agonists alter mitochondrial function and induce autophagy in airway smooth muscle cells

    Article • AJP Lung Cellular and Molecular Physiology, July 2017, American Physiological Society

    Dr Pawan Sharma

  62. Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice

    Article • Scientific Reports, April 2017, Springer Science + Business Media

    Dr Pawan Sharma

  63. Autophagy and airway fibrosis: Is there a link?

    Article • F1000Research, April 2017, Faculty of 1000, Ltd.

    Dr Deepak Deshpande, Anudeep Kota, Brian Oliver, Dr Pawan Sharma, Mehra Haghi

  64. Targeting ASK1 in preventing airway smooth muscle growth: Implications for airway remodeling in COPD

    Article • European Respiratory Journal, September 2016, European Respiratory Society (ERS)

    Dr Pawan Sharma

  65. Antimitogenic effect of bitter taste receptor agonists on airway smooth muscle cells

    Article • AJP Lung Cellular and Molecular Physiology, February 2016, American Physiological Society

    Dr Pawan Sharma

  66. A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness?

    Article • Canadian Journal of Physiology and Pharmacology, March 2015, Canadian Science Publishing

    Dr Pawan Sharma

  67. Characterization of the dystrophin–glycoprotein complex in airway smooth muscle: role of δ-sarcoglycan in airway responsiveness 1

    Article • Canadian Journal of Physiology and Pharmacology, March 2015, Canadian Science Publishing

    Dr Pawan Sharma

  68. Mechanisms of glucocorticoid action and insensitivity in airways disease

    Article • Pulmonary Pharmacology & Therapeutics, December 2014, Elsevier

    Dr Pawan Sharma

  69. Role of Dystrophin in Airway Smooth Muscle Phenotype, Contraction and Lung Function

    Article • PLOS One, July 2014, PLOS

    Dr Pawan Sharma

  70. Airway mesenchymal cell death by mevalonate cascade inhibition: Integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, July 2014, Elsevier

    Dr Pawan Sharma

  71. Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease

    Article • Pharmacology & Therapeutics, July 2014, Elsevier

    Dr Pawan Sharma

  72. Phosphodiesterase 4 Inhibitors Augment the Ability of Formoterol to Enhance Glucocorticoid-Dependent Gene Transcription in Human Airway Epithelial Cells: A Novel Mechanism for the Clinical Efficacy of Roflumilast in Severe Chronic Obstructive Pulmonary...

    Article • Molecular Pharmacology, February 2013, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Pawan Sharma

  73. Models to study airway smooth muscle contraction in vivo, ex vivo and in vitro: Implications in understanding asthma

    Article • Pulmonary Pharmacology & Therapeutics, February 2013, Elsevier

    Dr Pawan Sharma

  74. Epithelium-dependent modulation of responsiveness of airways from caveolin-1 knockout mice is mediated through cyclooxygenase-2 and 5-lipoxygenase

    Article • Bone Marrow Transplantation, September 2012, Wiley

    Dr Pawan Sharma

  75. Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts

    Article • Cell Death and Disease, June 2012, Springer Science + Business Media

    Dr Pawan Sharma

  76. Anti-Mitogenic Effects Of Bitter Taste Receptor (BTR) Agonists On Human Airway Smooth Muscle (ASM) Cells

    Article • May 2012, American Thoracic Society

    Dr Pawan Sharma

  77. Mevalonate Cascade Inhibition Induced Apoptosis, Autophagy, And ER-Stress In Airway Mesenchymal Cells: Regulatory Function Of Autophagy And Bcl2 Pro-Apoptotic Proteins

    Article • May 2012, American Thoracic Society

    Dr Pawan Sharma

  78. Reduction In Airway Smooth Muscle Contraction And Airway Narrowing By PDE4 Inhibitor Roflumilast Is Enhanced In Presence Of An Inhaled Corticosteroid

    Article • May 2012, American Thoracic Society

    Dr Pawan Sharma

  79. Phosphodiesterase 4 Inhibitors Enhance Glucocorticoid-Dependent Gene Transcription In Human Airway Epithelial Cells: A Mechanism For The Clinical Efficacy Of Roflumilast In Severe Chronic Obstructive Pulmonary Disease

    Article • May 2012, American Thoracic Society

    Dr Pawan Sharma

  80. Motility, Survival, and Proliferation

    Article • January 2012, Wiley

    Dr Pawan Sharma

  81. Airway Smooth Muscle Cells

    Article • July 2011, Wiley

    Dr Pawan Sharma

  82. Modifiers Of Camp Signaling Inhibit TGF-Beta1 Induced Fibrosis Through PKA Mediated Regulation Of The Map Kinase Pathway

    Article • May 2011, American Thoracic Society

    Dr Pawan Sharma

  83. Epithelium-Dependent Modulation Of Muscarinic Hyperresponsiveness Of Airways From Caveolin-1 Knockout Mice Is Mediated Through Cyclooxygenase-2

    Article • May 2011, American Thoracic Society

    Dr Pawan Sharma

  84. Autophagy Regulates Tgf-Beta1 Induced Fibrosis In Human Airway Smooth Muscle Cells

    Article • May 2011, American Thoracic Society

    Dr Pawan Sharma

  85. Glutamate Enhances Amphiregulin (AREG) Production from Human Airway Smooth Muscle Cells

    Article • Journal of Allergy and Clinical Immunology, February 2011, Elsevier

    Dr Pawan Sharma

  86. Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53

    Article • PLOS One, January 2011, PLOS

    Dr Pawan Sharma

  87.  -Dystroglycan binds caveolin-1 in smooth muscle: a functional role in caveolae distribution and Ca2+ release

    Article • Journal of Cell Science, August 2010, The Company of Biologists

    Dr Pawan Sharma

  88. Dual Role For P53 In Simvastatin-Induced Cell Death In Airway Mesenchymal Cells

    Article • May 2010, American Thoracic Society

    Dr Pawan Sharma

  89. The Dystrophin Glycoprotein Complex (DGC) Regulates Spatial Organization And Function Of Caveolae In Human Airway Smooth Muscle Cells

    Article • May 2010, American Thoracic Society

    Dr Pawan Sharma

  90. Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, April 2010, Elsevier

    Dr Pawan Sharma

  91. S100A8/A9 as a Pro-inflammatory Cytokine in Obstructive Airway Disease Via the Multi-Ligand Receptor, RAGE

    Article • Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, December 2009, Bentham Science Publishers

    Dr Pawan Sharma

  92. Airway smooth muscle in asthma: Phenotype plasticity and function

    Article • Pulmonary Pharmacology & Therapeutics, October 2009, Elsevier

    Dr Pawan Sharma

  93. Role of Dystrophin in Contractile Phenotype Expression and Ca2+Mobilization in Airway Smooth Muscle.

    Article • April 2009, American Thoracic Society

    Dr Pawan Sharma

  94. hTERT-Immortalized Human Airway Smooth Muscle Cells Retain a Multifunctional Phenotype.

    Article • April 2009, American Thoracic Society

    Dr Pawan Sharma

  95. β-Dystroglycan Interacts with Caveolin-1: Central Role in Intracellular Calcium Mobilization by Airway Smooth Muscle.

    Article • April 2009, American Thoracic Society

    Dr Pawan Sharma

  96. Pharmacology of a Novel, Orally Active PDE4 Inhibitor

    Article • Pharmacology, January 2009, Karger Publishers

    Dr Pawan Sharma, Dr. MAHESH KUMAR SETH

  97. Pharmacodynamic and pharmacokinetic characterisation of RBx 7796: a novel 5-lipoxygenase inhibitor

    Article • Inflammation Research, March 2008, Springer Science + Business Media

    Dr Pawan Sharma

  98. Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation

    Article • AJP Lung Cellular and Molecular Physiology, January 2008, American Physiological Society

    Dr Pawan Sharma

  99. Insulin increases the expression of contractile phenotypic markers in airway smooth muscle

    Article • AJP Cell Physiology, July 2007, American Physiological Society

    Dr Pawan Sharma

  100. Emerging molecular targets for the treatment of pre-eclampsia

    Article • Expert Opinion on Therapeutic Targets, June 2001, Taylor & Francis

    Dr Pawan Sharma