All Stories

  1. Septin7 is essential in early hematopoiesis, but redundant at later stages

    Article • April 2025, Cold Spring Harbor Laboratory Press

    Manoj B Menon

  2. RNA G-quadruplexes regulate mammalian mirtron biogenesis

    Article • Journal of Biological Chemistry, March 2025, Elsevier

    Manoj B Menon

  3. Kinase Inhibitor-Induced Cell-Type Specific Vacuole Formation in the Absence of Canonical ATG5-Dependent Autophagy Initiation Pathway

    Article • Molecular and Cellular Biology, February 2025, Taylor & Francis

    Manoj B Menon

  4. Bio-reductive Co(iii)–doxorubicin complex for cancer cell-selective delivery of doxorubicin and potent anticancer activity

    Article • RSC Medicinal Chemistry, January 2025, Royal Society of Chemistry

    Manoj B Menon

  5. Kinase inhibitor-induced cell-type specific vacuole formation in the absence of canonical ATG5-dependent autophagy

    Article • August 2023, Cold Spring Harbor Laboratory Press

    Manoj B Menon

  6. 5-Iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling

    Article • Cell Death Discovery, July 2023, Springer Science + Business Media

    Manoj B Menon

  7. 5-iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Manoj B Menon

  8. Decoding post‐translational modifications of mammalian septins

    Article • Cytoskeleton, February 2023, Wiley

    Manoj B Menon

  9. PRMT5-mediated regulatory arginine methylation of RIPK3

    Article • Cell Death Discovery, January 2023, Springer Science + Business Media

    Manoj B Menon

  10. Selective Depletion of ZAP-Binding CpG Motifs in HCV Evolution

    Article • Pathogens, December 2022, MDPI AG

    Manoj B Menon

  11. Hepatitis B Virus-Encoded HBsAg Contributes to Hepatocarcinogenesis by Inducing the Oncogenic Long Noncoding RNA LINC00665 through the NF-κB Pathway

    Article • Microbiology Spectrum, August 2022, ASM Journals

    Manoj B Menon

  12. PRMT5-mediated regulatory arginine methylation of RIPK3

    Article • August 2022, Cold Spring Harbor Laboratory Press

    Manoj B Menon

  13. The Slowing Rate of CpG Depletion in SARS-CoV-2 Genomes Is Consistent with Adaptations to the Human Host

    Article • Molecular Biology and Evolution, February 2022, Oxford University Press (OUP)

    Manoj B Menon

  14. Cdc42‐Borg4‐Septin7 axis regulates HSC polarity and function

    Article • EMBO Reports, October 2021, EMBO

    Manoj B Menon

  15. Mutation landscape of SARS-CoV-2 reveals five mutually exclusive clusters of leading and trailing single nucleotide substitutions

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Manoj B Menon

  16. Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2

    Article • Cell Reports, June 2019, Elsevier

    Manoj B Menon

  17. Beclin 1 Phosphorylation – at the Center of Autophagy Regulation

    Article • Frontiers in Cell and Developmental Biology, October 2018, Frontiers

    Manoj B Menon

  18. Non-coding transcript variants of protein-coding genes – what are they good for?

    Article • RNA Biology, September 2018, Taylor & Francis

    Manoj B Menon

  19. Septins: Active GTPases or just GTP-binding proteins?

    Article • Cytoskeleton, August 2018, Wiley

    Manoj B Menon

  20. Differentiated macrophages acquire a pro-inflammatory and cell death–resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1

    Article • Journal of Biological Chemistry, June 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Manoj B Menon

  21. MK2–TNF–Signaling Comes Full Circle

    Article • Trends in Biochemical Sciences, March 2018, Elsevier

    Matthias Gaestel, Manoj B Menon

  22. To die or not to die: Regulatory feedback phosphorylation circuits determine receptor-interacting protein kinase-1 (RIPK1) function

    Article • Molecular & Cellular Oncology, November 2017, Taylor & Francis

    Matthias Gaestel, Manoj B Menon

  23. p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection

    Article • Nature Cell Biology, September 2017, Springer Science + Business Media

    Manoj B Menon

  24. Na+/H+exchanger NHE1 and NHE2 have opposite effects on migration velocity in rat gastric surface cells

    Article • Journal of Cellular Physiology, February 2017, Wiley

    Manoj B Menon

  25. IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes

    Article • Frontiers in Physiology, February 2017, Frontiers

    Manoj B Menon

  26. TPL2 meets p38MAPK: emergence of a novel positive feedback loop in inflammation

    Article • Biochemical Journal, September 2016, Portland Press Ltd.

    Manoj B Menon

  27. Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics

    Article • Cancer Cell, September 2016, Elsevier

    Manoj B Menon

  28. GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis

    Article • Scientific Reports, January 2016, Springer Science + Business Media

    Manoj B Menon, Dr Manuel H Taft

  29. Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK

    Article • PLOS One, August 2015, PLOS

    Matthias Gaestel, Manoj B Menon

  30. The problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research

    Article • Autophagy, June 2015, Taylor & Francis

    Manoj B Menon

  31. Sep(t)arate or not - how some cells take septin-independent routes through cytokinesis

    Article • Journal of Cell Science, February 2015, The Company of Biologists

    Matthias Gaestel, Manoj B Menon

  32. p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex

    Article • RNA, December 2014, Cold Spring Harbor Laboratory Press

    Matthias Gaestel, Manoj B Menon

  33. Resident CD4+ T cells accumulate in lymphoid organs after prolonged antigen exposure

    Article • Nature Communications, September 2014, Springer Science + Business Media

    Manoj B Menon

  34. Genetic Deletion of SEPT7 Reveals a Cell Type-Specific Role of Septins in Microtubule Destabilization for the Completion of Cytokinesis

    Article • PLoS Genetics, August 2014, PLOS

    Manoj B Menon

  35. Expression of fibulin-6 in failing hearts and its role for cardiac fibroblast migration

    Article • Cardiovascular Research, June 2014, European Society of Cardiology

    Matthias Gaestel, Manoj B Menon

  36. Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production

    Article • Biochemical Journal, December 2013, Portland Press Ltd.

    Matthias Gaestel, Manoj B Menon

  37. Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity

    Article • Proceedings of the National Academy of Sciences, September 2013, Proceedings of the National Academy of Sciences

    Matthias Gaestel, Manoj B Menon

  38. Mitogen-Activated Protein Kinase-Activated Protein Kinases 2 and 3 Regulate SERCA2a Expression and Fiber Type Composition To Modulate Skeletal Muscle and Cardiomyocyte Function

    Article • Molecular and Cellular Biology, April 2013, ASM Journals

    Matthias Gaestel, Manoj B Menon

  39. The Extracellular Signal-Regulated Kinase 3 (Mitogen-Activated Protein Kinase 6 [MAPK6])-MAPK-Activated Protein Kinase 5 Signaling Complex Regulates Septin Function and Dendrite Morphology

    Article • Molecular and Cellular Biology, April 2012, ASM Journals

    Matthias Gaestel, Manoj B Menon

  40. Guidelines for the use and interpretation of assays for monitoring autophagy

    Article • Autophagy, April 2012, Taylor & Francis

    Dave Bridges, Professor CIRO ISIDORO, Professor George Perry, Dr Takeshi Noda, Professor Nektarios Tavernarakis, Matthias Gaestel, Dr Francesca Demarchi, Maria Vaccaro, Juan Segura-Aguilar, Leonardo Travassos, Manoj B Menon, Isabelle Dugail, Dr Legembre Patrick, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Professor Godefridus J Peters, Professor Brigitte Galliot, Professor Luca Scorrano

  41. SB202190-Induced Cell Type-Specific Vacuole Formation and Defective Autophagy Do Not Depend on p38 MAP Kinase Inhibition

    Article • PLOS One, August 2011, PLOS

    Matthias Gaestel, Manoj B Menon

  42. MAPKAP kinases MK2 and MK3 in inflammation: Complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin

    Article • Biochemical Pharmacology, December 2010, Elsevier

    Matthias Gaestel, Manoj B Menon

  43. Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes

    Article • Nucleic Acids Research, November 2010, Oxford University Press (OUP)

    Matthias Gaestel, Manoj B Menon

  44. p38 MAP Kinase and MAPKAP Kinases MK2/3 Cooperatively Phosphorylate Epithelial Keratins

    Article • Journal of Biological Chemistry, August 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Matthias Gaestel, Manoj B Menon

  45. Fluorescence-based quantitative scratch wound healing assay demonstrating the role of MAPKAPK-2/3 in fibroblast migration

    Article • Cell Motility and the Cytoskeleton, December 2009, Wiley

    Matthias Gaestel, Manoj B Menon