All Stories

  1. Opposing effects of 25‐hydroxy‐ and 1α,25‐dihydroxy‐vitamin D 3 on pro‐cachectic cytokine‐and cancer conditioned medium‐induced atrophy in C2C12 myotubes

    Article • Acta Physiologica, March 2019, Wiley

    Nicoletta Filigheddu

  2. Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting

    Article • Oxidative Medicine and Cellular Longevity, January 2018, Hindawi Publishing Corporation

    Nicoletta Filigheddu, Professor Emilio Hirsch, Elisabeth Wyart, Alessandra Ghigo

  3. Mitochondrial metabolism and cancer

    Article • Cell Research, December 2017, Nature

    Nicoletta Filigheddu

  4. The role of vitamin D in cancer cachexia

    Article • Current Opinion in Supportive and Palliative Care, December 2017, Wolters Kluwer Health

    Nicoletta Filigheddu

  5. Unacylated Ghrelin Enhances Satellite Cell Function and Relieves the Dystrophic Phenotype in Duchenne Muscular Dystrophy mdx Model

    Article • Stem Cells, May 2017, Wiley

    Professor Stefano Geuna, Nicoletta Filigheddu, Giulia Ruozi

  6. Unacylated Ghrelin Reduces Skeletal Muscle Reactive Oxygen Species Generation and Inflammation and Prevents High-Fat Diet–Induced Hyperglycemia and Whole-Body Insulin Resistance in Rodents

    Article • Diabetes, January 2016, American Diabetes Association

    Nicoletta Filigheddu, Giulia Ruozi, Spg Spgspg

  7. Unacylated ghrelin does not alter mitochondrial function, redox state and triglyceride content in rat liver in vivo

    Article • Clinical Nutrition Experimental, December 2015, Elsevier

    Nicoletta Filigheddu, Giulia Ruozi, Spg Spgspg

  8. Correction: Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential

    Article • PLoS ONE, October 2015, PLOS

    Nicoletta Filigheddu

  9. Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential

    Article • PLoS ONE, September 2015, PLOS

    Nicoletta Filigheddu

  10. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia

    Article • Nature Communications, June 2015, Nature

    Nicoletta Filigheddu, Giulia Ruozi

  11. Antifibrotic Activity of Acylated and Unacylated Ghrelin

    Article • International Journal of Endocrinology, January 2015, Hindawi Publishing Corporation

    Nicoletta Filigheddu

  12. The Diacylglycerol Kinase α/Atypical PKC/β1 Integrin Pathway in SDF-1α Mammary Carcinoma Invasiveness

    Article • PLoS ONE, June 2014, PLOS

    Nicoletta Filigheddu

  13. Acylated and unacylated ghrelin administration to blunt muscle wasting

    Article • Current Opinion in Clinical Nutrition & Metabolic Care, May 2014, Wolters Kluwer Health

    Nicoletta Filigheddu

  14. Ghrelin Gene Products in Acute and Chronic Inflammation

    Article • Archivum Immunologiae et Therapiae Experimentalis, April 2014, Springer Science + Business Media

    Nicoletta Filigheddu

  15. Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice

    Article • Journal of Clinical Investigation, January 2013, American Society for Clinical Investigation

    Nicoletta Filigheddu

  16. Ghrelin

    Article • January 2013, Elsevier

    Nicoletta Filigheddu

  17. Diacylglycerol kinase α mediates 17-β-estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30

    Article • Cellular Signalling, December 2011, Elsevier

    Nicoletta Filigheddu

  18. SAP-Mediated Inhibition of Diacylglycerol Kinase   Regulates TCR-Induced Diacylglycerol Signaling

    Article • The Journal of Immunology, November 2011, The American Association of Immunologists

    Nicoletta Filigheddu

  19. Diacylglycerol kinases are essential for hepatocyte growth factor-dependent proliferation and motility of Kaposi’s sarcoma cells

    Article • Cancer Science, May 2011, Wiley

    Nicoletta Filigheddu

  20. Diacylglycerol kinase α mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI

    Article • Proceedings of the National Academy of Sciences, February 2010, Proceedings of the National Academy of Sciences

    Nicoletta Filigheddu

  21. Differential Expression of MicroRNAs between Eutopic and Ectopic Endometrium in Ovarian Endometriosis

    Article • Journal of Biomedicine and Biotechnology, January 2010, Hindawi Publishing Corporation

    Nicoletta Filigheddu

  22. Morphological and biomolecular characterization of the neonatal olfactory bulb ensheathing cell line

    Article • Journal of Neuroscience Methods, December 2009, Elsevier

    Nicoletta Filigheddu

  23. Calcium signals activated by ghrelin and D-Lys3-GHRP-6 ghrelin antagonist in developing dorsal root ganglion glial cells

    Article • Cell Calcium, September 2009, Elsevier

    Nicoletta Filigheddu

  24. Diacylglycerol Kinase-  Mediates Hepatocyte Growth Factor-induced Epithelial Cell Scatter by Regulating Rac Activation and Membrane Ruffling

    Article • Molecular Biology of the Cell, September 2007, American Society for Cell Biology (ASCB)

    Nicoletta Filigheddu

  25. Diacylglycerol kinase-α phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility

    Article • Oncogene, August 2007, Nature

    Nicoletta Filigheddu

  26. Ghrelin and Des-Acyl Ghrelin Promote Differentiation and Fusion of C2C12 Skeletal Muscle Cells

    Article • Molecular Biology of the Cell, January 2007, American Society for Cell Biology (ASCB)

    Nicoletta Filigheddu

  27. p38 MAPK turns hepatocyte growth factor to a death signal that commits ovarian cancer cells to chemotherapy-induced apoptosis

    Article • International Journal of Cancer, June 2006, Wiley

    Nicoletta Filigheddu

  28. Role of phosphatidylinositol 3-kinase in the development of hepatocyte preconditioning

    Article • Gastroenterology, September 2004, Elsevier

    Nicoletta Filigheddu

  29. Activation of diacylglycerol kinase α is required for VEGF-induced angiogenic signaling in vitro

    Article • Oncogene, May 2004, Nature

    Nicoletta Filigheddu

  30. Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT

    Article • The Journal of Cell Biology, December 2002, Rockefeller University Press

    Nicoletta Filigheddu

  31. Hexarelin Protects H9c2 Cardiomyocytes from Doxorubicin-Induced Cell Death

    Article • Endocrine, January 2001, Springer Science + Business Media

    Nicoletta Filigheddu