All Stories

  1. An MRI approach to assess placental function in healthy humans and sheep
  2. Themed issue on the DOHaD workshop on Fetal, Placental and Pediatric Imaging
  3. COVID-19: can we treat the mother without harming her baby?
  4. In utero substrate restriction by placental insufficiency or maternal undernutrition decreases optical redox ratio in foetal perirenal fat
  5. PPARγ activation in late gestation does not promote surfactant maturation in the fetal sheep lung
  6. The reliance on α‐adrenergic receptor stimuli for blood pressure regulation in the chronically hypoxaemic fetus is not dependent on post‐ganglionic activation
  7. Impact of in vitro embryo culture and transfer on blood pressure regulation in the adolescent lamb
  8. Development of a method to determine cytochrome P450 1A2, 2C9, 2D6 and 3A4 activity sheep hepatic microsomes
  9. DOHaD in the land down under: 11th World Congress 2019
  10. Seeing the fetus from a DOHaD perspective: discussion paper from the advanced imaging techniques of DOHaD applications workshop held at the 2019 DOHaD World Congress
  11. The impact of intrauterine growth restriction on cytochrome P450 enzyme expression and activity
  12. Fetal Growth Restriction and Hypertension in the Offspring: Mechanistic Links and Therapeutic Directions
  13. Umbilical vein infusion of Prostaglandin I 2 increases ductus venosus shunting of oxygen rich blood but does not increase cerebral oxygen delivery in the fetal sheep
  14. Technique for comprehensive fetal hepatic blood flow assessment in sheep using 4D flow MRI
  15. Identification of Novel miRNAs Involved in Cardiac Repair Following Infarction in Fetal and Adolescent Sheep Hearts
  16. Editorial: Outcomes from the 2018 Australia and New Zealand Developmental Origins of Health and Disease (ANZ DOHaD) scientific meeting
  17. The impact of maternal asthma during pregnancy on offspring retinal microvascular structure and its relationship to placental growth factor production in utero
  18. Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs
  19. Feasibility of ventricular volumetry by cardiovascular MRI to assess cardiac function in the fetal sheep
  20. Normal human and sheep fetal vessel oxygen saturations by T2 magnetic resonance imaging
  21. The Journal of Developmental Origins of Health and Disease (JDOHaD) celebrates the contribution of women in DOHaD on International Women’s Day
  22. Differential gene responses 3 days following infarction in the fetal and adolescent sheep heart
  23. Fetal cardiovascular response to acute hypoxia during maternal anesthesia
  24. Cardiorespiratory consequences of intrauterine growth restriction: Influence of timing, severity and duration of hypoxaemia
  25. Maternal periconceptional and first trimester protein restriction in beef heifers: effects on placental parameters and fetal and neonatal calf development
  26. Detecting metabolic differences in fetal and adult sheep adipose and skeletal muscle tissue
  27. Subcutaneous maternal resveratrol treatment increases uterine artery blood flow in the pregnant ewe and increases fetal but not cardiac growth
  28. Placental glucocorticoid receptor isoforms in a sheep model of maternal allergic asthma
  29. Maternal allergic asthma during pregnancy alters fetal lung and immune development in sheep: potential mechanisms for programming asthma and allergy
  30. Arginine Vasopressin improves cerebral perfusion following controlled haemorrhage in adult ewes
  31. Considerations in selecting postoperative analgesia for pregnant sheep following fetal instrumentation surgery
  32. Systematic review: Impact of resveratrol exposure during pregnancy on maternal and fetal outcomes in animal models of human pregnancy complications—Are we ready for the clinic?
  33. Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period
  34. DOHaD in Indigenous populations: DOHaD, epigenetics, equity and race
  35. Fetal hemodynamics and cardiac streaming assessed by 4D flow cardiovascular magnetic resonance in fetal sheep
  36. Improving pregnancy outcomes in humans through studies in sheep
  37. Bright lights down under: Metal ion complexes turning the spotlight on metabolic processes at the cellular level
  38. And the beat goes on
  39. Maternal sleep during pregnancy and poor fetal outcomes: A scoping review of the literature with meta-analysis
  40. Reducing back sleep in late pregnancy is possible with positional therapy and may have benefits
  41. Intrauterine growth restriction may reduce hepatic drug metabolism in the early neonatal period
  42. IUGR decreases cardiomyocyte endowment and alters cardiac metabolism in a sex- and cause-of-IUGR-specific manner
  43. The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults
  44. Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic
  45. Mitochondrial imaging in live or fixed tissues using a luminescent iridium complex
  46. Maternal undernutrition in late gestation increases IGF2 signalling molecules and collagen deposition in the right ventricle of the fetal sheep heart
  47. Does poor fetal growth influence the extent of fetal exposure to maternal medications?
  48. A fibre optic fluorescence sensor to measure redox level in tissues
  49. Feasibility of phase-contrast cine magnetic resonance imaging for measuring blood flow in the sheep fetus
  50. Adverse Intrauterine Environment and Cardiac miRNA Expression
  51. Label-free imaging of redox status and collagen deposition showing metabolic differences in the heart
  52. Normalisation of surfactant protein -A and -B expression in the lungs of low birth weight lambs by 21 days old
  53. Australian Perspectives: Outcomes from the 2016 ANZ DOHaD Scientific Meeting
  54. Feasibility of detecting myocardial infarction in the sheep fetus using late gadolinium enhancement CMR imaging
  55. Differential effects of late gestation maternal overnutrition on the regulation of surfactant maturation in fetal and postnatal life
  56. Investigating Intracellular Localisation and Cytotoxicity Trends for Neutral and Cationic Iridium Tetrazolato Complexes in Live Cells
  57. Imaging and lipidomics methods for lipid analysis in metabolic and cardiovascular disease
  58. Gene expression allelic imbalance in ovine brown adipose tissue impacts energy homeostasis
  59. Maternal chronic hypoxia increases expression of genes regulating lung liquid movement and surfactant maturation in male fetuses in late gestation
  60. Label-free imaging of healthy and infarcted fetal sheep hearts by two-photon microscopy
  61. Akt signaling as a mediator of cardiac adaptation to low birth weight
  62. Maternal Undernutrition Increases Fibrosis in the Late Gestation Fetal Heart
  63. Chronic hypoxaemia as a molecular regulator of fetal lung development: implications for risk of respiratory complications at birth
  64. Maternal obesity mediated predisposition to respiratory complications at birth and in later life: understanding the implications of the obesogenic intrauterine environment
  65. Early restriction of placental growth results in placental structural and gene expression changes in late gestation independent of fetal hypoxemia
  66. Antidepressant Use in Late Gestation and Breastfeeding Rates at Discharge from Hospital
  67. A review of fundamental principles for animal models of DOHaD research: an Australian perspective
  68. Australian perspectives: outcomes from the 2015 Australia and New Zealand Developmental Origins of Health and Disease (ANZ DOHaD) scientific meeting
  69. Risk of Respiratory Distress Syndrome and Efficacy of Glucocorticoids
  70. miR-133a and Target Gene Expression in the Foetus and 6 Month Old Sheep Heart in Response to Myocardial Infarction
  71. Is There a Dirty Side to Personal Care Products?
  72. Nutrition in Pregnancy: Optimising Maternal Diet and Fetal Adaptations to Altered Nutrient Supply
  73. Regulation of lung maturation by prolyl hydroxylase domain inhibition in the lung of the normally grown and placentally restricted fetus in late gestation
  74. Limited fetal metabolism of rosiglitazone: Elimination via the maternal compartment in the pregnant ewe
  75. Impact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetuses
  76. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
  77. Structural and molecular regulation of lung maturation by intratracheal vascular endothelial growth factor administration in the normally grown and placentally restricted fetus
  78. Evolution, Development, and Function of the Pulmonary Surfactant System in Normal and Perturbed Environments
  79. Association of early and late maternal smoking during pregnancy with offspring body mass index at 4 to 5 years of age
  80. Maternal Nutrient Restriction Alters Ca2+ Handling Properties and Contractile Function of Isolated Left Ventricle Bundles in Male But Not Female Juvenile Rats
  81. Prenatal antidepressant exposure and child behavioural outcomes at 7 years of age: a study within the Danish National Birth Cohort
  82. The early origins of obesity and insulin resistance: timing, programming and mechanisms
  83. Development of an experimental model of maternal allergic asthma during pregnancy
  84. Effect of periconceptional nutrition on the growth, behaviour and survival of the neonatal lamb
  85. Mature Surfactant Protein-B Expression by Immunohistochemistry as a Marker for Surfactant System Development in the Fetal Sheep Lung
  86. Impact of periconceptional and preimplantation undernutrition on factors regulating myogenesis and protein synthesis in muscle of singleton and twin fetal sheep
  87. Regulation of microRNA during cardiomyocyte maturation in sheep
  88. Recent developments on the role of epigenetics in obesity and metabolic disease
  89. Increased lung prolyl hydroxylase and decreased glucocorticoid receptor are related to decreased surfactant protein in the growth-restricted sheep fetus
  90. Postnatal consequences of prenatal nicotine exposure
  91. IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb
  92. The Periconceptional Environment and Cardiovascular Disease: Does In Vitro Embryo Culture and Transfer Influence Cardiovascular Development and Health?
  93. Low birth weight activates the renin-angiotensin system, but limits cardiac angiogenesis in early postnatal life
  94. Impact of chronic hypoxemia on blood flow to the brain, heart, and adrenal gland in the late-gestation IUGR sheep fetus
  95. Placental Adaptations in Growth Restriction
  96. Late gestation over nutrition alters the cardiac metabolic profile
  97. Intrafetal glucose infusion alters glucocorticoid signaling and reduces surfactant protein mRNA expression in the lung of the late-gestation sheep fetus
  98. Chronic Hypoxemia in Late Gestation Decreases Cardiomyocyte Number but Does Not Change Expression of Hypoxia-Responsive Genes
  99. Embryo number and periconceptional undernutrition in the sheep have differential effects on adrenal epigenotype, growth, and development
  100. Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep
  101. Maternal obesity or weight loss around conception impacts hepatic fatty acid metabolism in the offspring
  102. Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus
  103. PW295 Is the heart of the IUGR fetus hypoxic in early gestation?
  104. PW290 Impact of in vitro culture and embryo transfer on cardiomyocyte endowment in postnatal life
  105. Scientific Abstracts
  106. Epigenetics and human obesity
  107. Effect of Environment and Aging on the Pulmonary Surfactant System
  108. The Development of the Pulmonary Surfactant System
  109. Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model
  110. Periconceptional Undernutrition Programs Changes in Insulin-Signaling Molecules and MicroRNAs in Skeletal Muscle in Singleton and Twin Fetal Sheep1
  111. Differential Effects of Exposure to Maternal Obesity or Maternal Weight Loss during the Periconceptional Period in the Sheep on Insulin Signalling Molecules in Skeletal Muscle of the Offspring at 4 Months of Age
  112. Maternal Dietary Restriction During the Periconceptional Period in Normal-Weight or Obese Ewes Results in Adrenocortical Hypertrophy, an Up-Regulation of the JAK/STAT and Down-Regulation of the IGF1R Signaling Pathways in the Adrenal of the Postnatal Lamb
  113. The fetal sheep lung does not respond to cortisol infusion during the late canalicular phase of development
  114. Prenatal exposure to selective serotonin reuptake inhibitors and childhood overweight at 7 years of age
  115. Alteration of cardiac glucose metabolism in association to low birth weight: Experimental evidence in lambs with left ventricular hypertrophy
  116. Long-Term Effects of Prenatal SSRI Exposure on Child Growth: Weighing the Evidence
  117. Regulation of fetal lung development in response to maternal overnutrition
  118. Introduction: Celebrating Emeritus Scientia Professor Eugenie R Lumbers AM and Professor Caroline McMillen
  119. Impact of embryo number and periconceptional undernutrition on factors regulating adipogenesis, lipogenesis, and metabolism in adipose tissuein the sheep fetus
  120. Impact of maternal overnutrition on gluconeogenic factors and methylation of the phosphoenolpyruvate carboxykinase promoter in the fetal and postnatal liver
  121. Dietary restriction in the periconceptional period in normal-weight or obese ewes results in increased abundance of angiotensin-converting enzyme (ACE) and angiotensin type 1 receptor (AT1R) in the absence of changes in ACE or AT1R methylation in the adre
  122. The Australian Early Origins of Hypertension Workshop: A celebration of the scientific contributions made by Emeritus Scientia Professor Eugenie R Lumbers AM and Professor Caroline McMillen
  123. Maternal undernutrition during the first week after conception results in decreased expression of glucocorticoid receptor mRNA in the absence of GR exon 17 hypermethylation in the fetal pituitary in late gestation
  124. Maternal undernutrition around the time of conception and embryo number each impact on the abundance of key regulators of cardiac growth and metabolism in the fetal sheep heart
  125. The effect of placental restriction on insulin signaling and lipogenic pathways in omental adipose tissue in the postnatal lamb
  126. Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring
  127. Antidepressant use and gestational hypertension: does evidence support causality?
  128. Does maternal obesity change cardiomyocyte endowment?
  129. Basic Experimental and Clinical Advances in the Mechanisms Underlying Abnormal Pregnancy Outcomes
  130. Methodological challenges in using routinely collected health data to investigate long-term effects of medication use during pregnancy
  131. Early origins of heart disease: Low birth weight and the role of the insulin‐like growth factor system in cardiac hypertrophy
  132. Activation of IGF-2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus
  133. Neonatal Outcomes After Late-Gestation Exposure to Selective Serotonin Reuptake Inhibitors
  134. 237 CARDIOMYOCYTE NUMBER AND EXPRESSION OF FATTY ACID β-OXIDATIVE GENES ARE DIFFERENTIALLY AFFECTED BY THE CAUSE OF FETAL GROWTH RESTRICTION AND SEX
  135. 253 IMPACT OF LOW BIRTH WEIGHT ON THE EXPRESSION OF THE RENIN-ANGIOTENSIN SYSTEM, FACTORS WHICH REGULATE AUTOPHAGY, FIBROSIS AND CAPILLARY DENSITY IN THE HEART DURING EARLY POSTNATAL LIFE
  136. 80 IMPACT OF IN VITRO CULTURE AND EMBRYO TRANSFER ON THE IGF-PHOSPHATIDYL-3 KINASE (PI3K) MEDIATED SIGNALLING PATHWAY IN THE HEART OF THE FETAL SHEEP
  137. 254 THE ROLE OF RENIN-ANGIOTENSIN SYSTEM IN THE ADRENALS OF OFFSPRING AFTER EXPOSURE TO MATERNAL DIETARY RESTRICTION DURING THE PERICONCEPTIONAL PERIOD
  138. Early origins of heart disease: Low birth weight and determinants of cardiomyocyte endowment
  139. Long term impact of prenatal exposure to SSRIs on growth and body weight in childhood: Evidence from animal and human studies
  140. Drugs, chemicals and nutrition during pregnancy: impact on fetal, neonatal and adult health
  141. Does a growth-restricted fetus have fewer cardiomyocytes than a normally grown fetus?
  142. Investigating outcomes associated with medication use during pregnancy: A review of methodological challenges and observational study designs
  143. Maternal undernutrition reduces P-glycoprotein in guinea pig placenta and developing brain in late gestation
  144. Prenatal exposure to selective serotonin reuptake inhibitors and risk of childhood overweight
  145. Antenatal Steroids and the IUGR Fetus: Are Exposure and Physiological Effects on the Lung and Cardiovascular System the Same as in Normally Grown Fetuses?
  146. Exposed or not exposed? Exploring exposure classification in studies using administrative data to investigate outcomes following medication use during pregnancy
  147. Investigating Outcomes Following the Use of Selective Serotonin Reuptake Inhibitors for Treating Depression in Pregnancy
  148. Arrhythmogenic adverse effects of cardiac glycosides are mediated by redox modification of ryanodine receptors
  149. Fetal growth restriction and the programming of heart growth and cardiac insulin-like growth factor 2 expression in the lamb
  150. Prenatal development of the pulmonary surfactant system and the influence of hypoxia
  151. Changes in cardiac troponins with gestational age explain changes in cardiac muscle contractility in the sheep fetus
  152. Periconceptional nutrition and the early programming of a life of obesity or adversity
  153. Simple HPLC method for determination of rosiglitazone in sheep plasma and amniotic fluid and its application in a pregnant sheep model
  154. Maternal Obesity and the Early Origins of Childhood Obesity: Weighing Up the Benefits and Costs of Maternal Weight Loss in the Periconceptional Period for the Offspring
  155. Maternal undernutrition alters fat cell size distribution, but not lipogenic gene expression, in the visceral fat of the late gestation guinea pig fetus
  156. Periconceptional undernutrition in normal and overweight ewes leads to increased adrenal growth and epigenetic changes in adrenal IGF2/H19 gene in offspring
  157. Intrauterine growth restriction delays surfactant protein maturation in the sheep fetus
  158. Does the intrauterine growth-restricted fetus benefit from antenatal glucocorticoids?
  159. Fetal growth restriction, catch-up growth and the early origins of insulin resistance and visceral obesity
  160. Rosiglitazone Increases the Expression of Peroxisome Proliferator-Activated Receptor-γ Target Genes in Adipose Tissue, Liver, and Skeletal Muscle in the Sheep Fetus in Late Gestation
  161. The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle
  162. No Evidence for an Enhanced Role of Endothelial Nitric Oxide in the Maintenance of Arterial Blood Pressure in the IUGR Sheep Fetus
  163. Intrauterine Growth Restriction and Differential Patterns of Hepatic Growth and Expression of IGF1, PCK2, and HSDL1 mRNA in the Sheep Fetus in Late Gestation1
  164. Fetal heart growth: IGF-1 and sex
  165. Review: Antenatal Glucocorticoid Treatment of The Growth-restricted Fetus: Benefit or Cost?
  166. The Early Origins of Later Obesity: Pathways and Mechanisms
  167. SHEEP MODELS OF INTRAUTERINE GROWTH RESTRICTION: FETAL ADAPTATIONS AND CONSEQUENCES
  168. Developmental Origins of Adult Health and Disease: The Role of Periconceptional and Foetal Nutrition
  169. Second-harmonic generation and two-photon-excited autofluorescence microscopy of cardiomyocytes: quantification of cell volume and myosin filaments
  170. Restriction of placental function alters heart development in the sheep fetus
  171. Two-day subpressor cortisol infusion increases proliferation of cardiomyocytes in the late gestation sheep fetus
  172. Contractile and Ca2+-handling properties of the right ventricular papillary muscle in the late-gestation sheep fetus
  173. Role of Endogenous Serotonin in Modulating Genioglossus Muscle Activity in Awake and Sleeping Rats
  174. Maternal Fluoxetine Infusion Does Not Alter Fetal Endocrine and Biophysical Circadian Rhythms in Pregnant Sheep
  175. Cerebral Blood Flow during Spontaneous and Cholinergically Induced Behavioral States in the Sheep Fetus
  176. Restriction of placental growth results in greater hypotensive response to α-adrenergic blockade in fetal sheep during late gestation
  177. Impact and mechanisms of fetal physiological programming
  178. Chronic Maternal Fluoxetine Infusion in Pregnant Sheep: Effects on the Maternal and Fetal Hypothalamic-Pituitary-Adrenal Axes
  179. Role of inhibitory amino acids in control of hypoglossal motor outflow to genioglossus muscle in naturally sleeping rats
  180. GABAA receptor antagonism at the hypoglossal motor nucleus increases genioglossus muscle activity in NREM but not REM sleep
  181. Glycine at hypoglossal motor nucleus: genioglossus activity, CO2 responses, and the additive effects of GABA
  182. Effect of Maternal Fluoxetine Administration on Uterine Blood Flow, Fetal Blood Gas Status, and Growth
  183. Fetal behavioural state changes following maternal fluoxetine infusion in sheep
  184. The effects of `sleep promoting agents' on behavioural state in the ovine fetus