All Stories

  1. Measuring the Activation of Cell Death Pathways upon Inhibition of Metabolism

    Article • October 2018, Springer Science + Business Media

    Cristina Muñoz-Pinedo

  2. Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

    Article • FEBS Journal, August 2018, Wiley

    Cristina Muñoz-Pinedo

  3. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Article • Cell Death and Differentiation, January 2018, Nature

    Abhishek Garg, Professor David M. Pereira, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis

  4. A role for caspase-8 and TRAIL-R2/DR5 in ER-stress-induced apoptosis

    Article • Cell Death and Differentiation, October 2017, Springer Science + Business Media

    Cristina Muñoz-Pinedo

  5. In the Hunger Games, the Winner Takes Everything

    Article • Trends in Biochemical Sciences, October 2017, Elsevier

    Cristina Muñoz-Pinedo

  6. Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors

    Article • Molecular and Cellular Biology, February 2017, ASM Journals

    Cristina Muñoz-Pinedo

  7. Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

    Article • Oncotarget, June 2016, Impact Journals, LLC

    Cristina Muñoz-Pinedo

  8. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang

  9. Cell death induced by endoplasmic reticulum stress

    Article • FEBS Journal, December 2015, Wiley

    Cristina Muñoz-Pinedo

  10. ATF4 mediates necrosis induced by glucose deprivation and apoptosis induced by 2-deoxyglucose in the same cells

    Article • FEBS Journal, August 2015, Wiley

    Cristina Muñoz-Pinedo

  11. The Importance of Being Dead: Cell Death Mechanisms Assessment in Anti-Sarcoma Therapy

    Article • Frontiers in Oncology, April 2015, Frontiers

    Cristina Muñoz-Pinedo

  12. "(Not) All (Dead) Things Share the Same Breath": Identification of Cell Death Mechanisms in Anticancer Therapy

    Article • Cancer Research, February 2015, American Association for Cancer Research (AACR)

    Cristina Muñoz-Pinedo

  13. Analysis of BH3-only proteins upregulated in response to oxygen/glucose deprivation in cortical neurons identifies Bmf but not Noxa as potential mediator of neuronal injury

    Article • Cell Death and Disease, October 2014, Nature

    Cristina Muñoz-Pinedo

  14. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    Article • Cell Death and Differentiation, September 2014, Nature

    Professor Nektarios Tavernarakis, Cristina Muñoz-Pinedo, MD, PhD Klas Blomgren

  15. Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking

    Article • Cell Death and Differentiation, August 2014, Nature

    Cristina Muñoz-Pinedo

  16. Autosis: a new addition to the cell death tower of babel

    Article • Cell Death and Disease, July 2014, Nature

    Cristina Muñoz-Pinedo

  17. Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein

    Article • Cell Death and Disease, June 2014, Nature

    Cristina Muñoz-Pinedo

  18. Regulation of Cancer Metabolism by Oncogenes and Tumor Suppressors

    Article • January 2014, Elsevier

    Cristina Muñoz-Pinedo

  19. Glucose-starved Cells Do Not Engage in Prosurvival Autophagy

    Article • Journal of Biological Chemistry, September 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Cristina Muñoz-Pinedo

  20. El metabolismo del cáncer

    Article • August 2013, Sociedad Espanola de Bioquimica y Biologia Molecular (SEBBM)

    Cristina Muñoz-Pinedo

  21. Exploiting Tumor Vulnerabilities: Epigenetics, Cancer Metabolism and the mTOR Pathway in the Era of Personalized Medicine

    Article • Cancer Research, May 2013, American Association for Cancer Research (AACR)

    Cristina Muñoz-Pinedo

  22. Stalling the Engine of Resistance: Targeting Cancer Metabolism to Overcome Therapeutic Resistance

    Article • Cancer Research, April 2013, American Association for Cancer Research (AACR)

    Cristina Muñoz-Pinedo

  23. Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy

    Article • Brain, December 2012, Oxford University Press (OUP)

    Cristina Muñoz-Pinedo

  24. Emerging concepts: linking hypoxic signaling and cancer metabolism

    Article • Cell Death and Disease, June 2012, Nature

    Cristina Muñoz-Pinedo

  25. Emerging concepts: linking hypoxic signaling and cancer metabolism

    Article • Cell Death and Disease, May 2012, Nature

    Cristina Muñoz-Pinedo

  26. Cancer metabolism: current perspectives and future directions

    Article • Cell Death and Disease, January 2012, Nature

    Cristina Muñoz-Pinedo

  27. Signaling Pathways that Regulate Life and Cell Death: Evolution of Apoptosis in the Context of Self-Defense

    Article • January 2012, Springer Science + Business Media

    Cristina Muñoz-Pinedo

  28. 2-Deoxyglucose Induces Noxa-Dependent Apoptosis in Alveolar Rhabdomyosarcoma

    Article • Cancer Research, September 2011, American Association for Cancer Research (AACR)

    Cristina Muñoz-Pinedo

  29. Dying for Something to Eat: How Cells Respond to Starvation

    Article • The Open Cell Signaling Journal, April 2011, Bentham Science Publishers

    Cristina Muñoz-Pinedo

  30. Sugar-free approaches to cancer cell killing

    Article • Oncogene, October 2010, Nature

    Cristina Muñoz-Pinedo

  31. Resistance to Caspase-Independent Cell Death Requires Persistence of Intact Mitochondria

    Article • Developmental Cell, May 2010, Elsevier

    Cristina Muñoz-Pinedo

  32. DeathBase: a database on structure, evolution and function of proteins involved in apoptosis and other forms of cell death

    Article • Cell Death and Differentiation, April 2010, Springer Science + Business Media

    Cristina Muñoz-Pinedo

  33. Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells

    Article • Cell Death and Differentiation, March 2010, Springer Science + Business Media

    Cristina Muñoz-Pinedo

  34. Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation

    Article • Oncogene, December 2009, Springer Science + Business Media

    Cristina Muñoz-Pinedo

  35. Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells

    Article • Proceedings of the National Academy of Sciences, February 2009, Proceedings of the National Academy of Sciences

    Cristina Muñoz-Pinedo

  36. Measuring apoptosis at the single cell level

    Article • Methods, March 2008, Elsevier

    Cristina Muñoz-Pinedo

  37. Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis

    Article • Nature, August 2007, Nature

    Cristina Muñoz-Pinedo

  38. Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration

    Article • Proceedings of the National Academy of Sciences, August 2006, Proceedings of the National Academy of Sciences

    Cristina Muñoz-Pinedo

  39. Cytochrome c is released in a single step during apoptosis

    Article • Cell Death and Differentiation, May 2005, Nature

    Cristina Muñoz-Pinedo

  40. Confocal restricted-height imaging of suspension cells (CRISC) in a PDMS microdevice during apoptosis

    Article • Lab on a Chip, January 2005, Royal Society of Chemistry

    Cristina Muñoz-Pinedo

  41. Thymidylate synthase inhibition triggers glucose-dependent apoptosis in p53-negative leukemic cells

    Article • FEBS Letters, July 2004, Wiley

    Cristina Muñoz-Pinedo

  42. Disruption of Mitochondrial Function during Apoptosis Is Mediated by Caspase Cleavage of the p75 Subunit of Complex I of the Electron Transport Chain

    Article • Cell, June 2004, Elsevier

    Cristina Muñoz-Pinedo

  43. Spanish Scientists Working Abroad

    Article • Science, April 2003, American Association for the Advancement of Science

    Cristina Muñoz-Pinedo

  44. Inhibition of Glucose Metabolism Sensitizes Tumor Cells to Death Receptor-triggered Apoptosis through Enhancement of Death-inducing Signaling Complex Formation and Apical Procaspase-8 Processing

    Article • Journal of Biological Chemistry, January 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Cristina Muñoz-Pinedo

  45. Death on the beach: a rosy forecast for the 21st century

    Article • Cell Death and Differentiation, September 2002, Nature

    Cristina Muñoz-Pinedo

  46. The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels

    Article • Oncogene, October 2001, Nature

    Cristina Muñoz-Pinedo

  47. Interferon-gamma Sensitizes Human Myeloid Leukemia Cells to Death Receptor-mediated Apoptosis by a Pleiotropic Mechanism

    Article • Journal of Biological Chemistry, February 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Cristina Muñoz-Pinedo

  48. Apoptosis of haematopoietic cells upon thymidylate synthase inhibition is independent of p53 accumulation and CD95–CD95 ligand interaction

    Article • Biochemical Journal, January 2001, Portland Press Ltd.

    Cristina Muñoz-Pinedo

  49. Bid acts on the permeability transition pore complex to induce apoptosis

    Article • Oncogene, December 2000, Nature

    Cristina Muñoz-Pinedo

  50. Apoptosis of haematopoietic cells upon thymidylate synthase inhibition is independent of p53 accumulation and CD95‒CD95 ligand interaction

    Article • Biochemical Journal, January 2000, Portland Press Ltd.

    Cristina Muñoz-Pinedo