All Stories

  1. Sensitive fluorescent detection of SARS-CoV-2 RNA using an enzymatic-based method

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, April 2025, Elsevier

    Cláudio J Maia

  2. A new approach for extracellular RNA recovery from Rhodovulum sulfidophilum

    Article • Analytical Biochemistry, January 2025, Elsevier

    Cláudio J Maia

  3. Propolis Protects GC-1spg Spermatogonial Cells against Tert-Butyl Hydroperoxide-Induced Oxidative Damage

    Article • International Journal of Molecular Sciences, January 2024, MDPI AG

    Cláudio J Maia

  4. Proteomic analysis of STEAP1 knockdown in human LNCaP prostate cancer cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 2023, Elsevier

    Cláudio J Maia

  5. Evaluation of Bile Salts on the Survival and Modulation of Virulence of Aliarcobacter butzleri

    Article • Antibiotics, August 2023, MDPI AG

    Cláudio J Maia

  6. Combined Therapies with Taxane-Based Chemotherapeutic Drugs in Prostate Cancer: Novel Insights and Future Directions

    Article • BioChem, August 2023, MDPI AG

    Cláudio J Maia

  7. Development of a novel electrochemical biosensor based on plastic antibodies for detection of STEAP1 biomarker in cancer

    Article • Bioelectrochemistry, August 2023, Elsevier

    Cláudio J Maia

  8. Combined Therapies with Taxanes Based-Chemotherapeutic Drugs in Prostate Cancer: Novel Insights and Future Directions

    Article • April 2023, MDPI AG

    Cláudio J Maia

  9. STEAP1 Knockdown Decreases the Sensitivity of Prostate Cancer Cells to Paclitaxel, Docetaxel and Cabazitaxel

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Cláudio J Maia

  10. STEAP1 regulation and its influence modulating the response of LNCaP prostate cancer cells to bicalutamide, enzalutamide and apalutamide

    Article • Molecular Medicine Reports, January 2023, Spandidos Publications

    Cláudio J Maia

  11. Mini-Bioreactor Platform for Membrane Protein Production in Komagataella pastoris

    Article • January 2023, Springer Science + Business Media

    Cláudio J Maia

  12. A chromatographic network for the purification of detergent-solubilized six-transmembrane epithelial antigen of the prostate 1 from Komagataella pastoris mini-bioreactor lysates

    Article • Journal of Chromatography A, December 2022, Elsevier

    Cláudio J Maia

  13. Vascular Response of Tetrabromobisphenol a in Rat Aorta: Calcium Channels Inhibition and Potassium Channels Activation

    Article • Toxics, September 2022, MDPI AG

    Cláudio J Maia

  14. Differential response of hepatocellular carcinoma glycolytic metabolism and oxidative stress markers after exposure to human amniotic membrane proteins

    Article • Molecular Biology Reports, June 2022, Springer Science + Business Media

    Cláudio J Maia

  15. Comprehensive Landscape of STEAP Family Members Expression in Human Cancers: Unraveling the Potential Usefulness in Clinical Practice Using Integrated Bioinformatics Analysis

    Article • Data, May 2022, MDPI AG

    Cláudio J Maia

  16. Pathways involved in the human vascular Tetrabromobisphenol A response: Calcium and potassium channels and nitric oxide donors

    Article • Toxicology, March 2022, Elsevier

    Cláudio J Maia

  17. Differential Response of Human Amniotic Membrane Proteins in Hepatocellular Carcinoma: Analysis of the Glycolytic Metabolism

    Article • December 2021, Springer Science + Business Media

    Cláudio J Maia

  18. Promoter Demethylation Upregulates STEAP1 Gene Expression in Human Prostate Cancer: In Vitro and In Silico Analysis

    Article • Life, November 2021, MDPI AG

    Cláudio J Maia

  19. Natural Products as Protective Agents for Male Fertility

    Article • BioChem, September 2021, MDPI AG

    Cláudio J Maia

  20. Enhanced Stability of Detergent-Free Human Native STEAP1 Protein from Neoplastic Prostate Cancer Cells upon an Innovative Isolation Procedure

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Cláudio J Maia

  21. UV-B filter octylmethoxycinnamate impaired the main vasorelaxant mechanism of human umbilical artery

    Article • Chemosphere, August 2021, Elsevier

    Cláudio J Maia

  22. The Performance of Minicircle DNA Versus Parental Plasmid in p53 Gene Delivery Into HPV-18-Infected Cervical Cancer Cells

    Article • Nucleic Acid Therapeutics, February 2021, SAGE Publications

    Cláudio J Maia

  23. Overexpression of regucalcin mitigates the ageing-related changes in oxidative stress and sperm quality

    Article • Theriogenology, November 2020, Elsevier

    Cláudio J Maia

  24. Effects of di(2-etilhexil) phthalate on human umbilical artery

    Article • Chemosphere, August 2019, Elsevier

    Cláudio J Maia

  25. Glycolysis Inhibition as a Strategy for Hepatocellular Carcinoma Treatment?

    Article • Current Cancer Drug Targets, December 2018, Bentham Science Publishers

    Dr Marco G Alves, Cláudio J Maia, Andreia Alves

  26. 542 Overexpression of the Calcium-Binding Protein Regucalcin Mitigates the Age-Associated Changes in Oxidative Stress and Semen Quality

    Article • The Journal of Sexual Medicine, July 2018, Oxford University Press (OUP)

    Cláudio J Maia

  27. Amniotic membrane extract differentially regulates human peripheral blood T cell subsets, monocyte subpopulations and myeloid dendritic cells

    Article • Cell and Tissue Research, March 2018, Springer Science + Business Media

    Mafalda Laranjo, Cláudio J Maia

  28. Knockdown of STEAP1 inhibits cell growth and induces apoptosis in LNCaP prostate cancer cells counteracting the effect of androgens

    Article • Medical Oncology, February 2018, Springer Science + Business Media

    Cláudio J Maia

  29. Targeting STEAP1 Protein in Human Cancer: Current Trends and Future Challenges

    Article • Current Cancer Drug Targets, February 2018, Bentham Science Publishers

    Cláudio J Maia

  30. Variability of MMP/TIMP and TGF-β1 Receptors throughout the Clinical Progression of Chronic Venous Disease

    Article • International Journal of Molecular Sciences, December 2017, MDPI AG

    Cláudio J Maia

  31. The stem cell factor (SCF)/c-KIT system in carcinogenesis of reproductive tissues: What does the hormonal regulation tell us?

    Article • Cancer Letters, October 2017, Elsevier

    Cláudio J Maia

  32. The protective effect of regucalcin against radiation-induced damage in testicular cells

    Article • Life Sciences, November 2016, Elsevier

    Cláudio J Maia

  33. The Emerging Role of Regucalcin as a Tumor Suppressor: Facts and Views

    Article • Current Molecular Medicine, September 2016, Bentham Science Publishers

    Dr Sílvia Socorro, Cláudio J Maia

  34. Endogenous Factors in the Recovery of Reproductive Function After Testicular Injury and Cancer

    Article • Current Molecular Medicine, September 2016, Bentham Science Publishers

    Cláudio J Maia

  35. Liver diseases: what is known so far about the therapy with human amniotic membrane?

    Article • Cell and Tissue Banking, August 2016, Springer Science + Business Media

    Cláudio J Maia, Mafalda Laranjo

  36. Regucalcin in hormone-dependent cancers: towards a candidate tumour suppressor gene?

    Article • European Journal of Cancer, July 2016, Elsevier

    Cláudio J Maia

  37. Effect of TGF-beta1 on MMP/TIMP and TGF-beta1 receptors in great saphenous veins and its significance on chronic venous insufficiency

    Article • Phlebology The Journal of Venous Disease, June 2016, SAGE Publications

    Cláudio J Maia, Pedro Serralheiro

  38. Oligoadenylate synthetase 1 (OAS1) expression in human breast and prostate cancer cases, and its regulation by sex steroid hormones

    Article • Advances in Modern Oncology Research, June 2016, PiscoMed Publishing Pte Ltd

    Cláudio J Maia

  39. Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug Resistance Proteins: Targets of Human Amniotic Membrane in Hepatocellular Carcinoma

    Article • Pathology & Oncology Research, March 2016, Springer Science + Business Media

    Cláudio J Maia, Mafalda Laranjo

  40. Advances in time course extracellular production of human pre-miR-29b from Rhodovulum sulfidophilum

    Article • Applied Microbiology and Biotechnology, February 2016, Springer Science + Business Media

    Cláudio J Maia

  41. Estrogens down-regulate the stem cell factor (SCF)/c-KIT system in prostate cells: Evidence of antiproliferative and proapoptotic effects

    Article • Biochemical Pharmacology, January 2016, Elsevier

    Cláudio J Maia

  42. Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin

    Article • Translational Research, December 2015, Elsevier

    Cláudio J Maia

  43. Suppressed glycolytic metabolism in the prostate of transgenic rats overexpressing calcium-binding protein regucalcin underpins reduced cell proliferation

    Article • Transgenic Research, November 2015, Springer Science + Business Media

    Cláudio J Maia

  44. Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma

    Article • Medical Oncology, October 2015, Springer Science + Business Media

    Ana Cristina Gonçalves, Cláudio J Maia, Mafalda Laranjo

  45. Effect of extracellular calcium on regucalcin expression and cell viability in neoplastic and non-neoplastic human prostate cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 2015, Elsevier

    Cláudio J Maia

  46. 5α-Dihydrotestosterone regulates the expression of L-type calcium channels and calcium-binding protein regucalcin in human breast cancer cells with suppression of cell growth

    Article • Medical Oncology, August 2015, Springer Science + Business Media

    Cláudio J Maia

  47. Androgens enhance the glycolytic metabolism and lactate export in prostate cancer cells by modulating the expression of GLUT1, GLUT3, PFK, LDH and MCT4 genes

    Article • Journal of Cancer Research and Clinical Oncology, June 2015, Springer Science + Business Media

    Cláudio J Maia

  48. Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer

    Article • The Prostate, March 2015, Wiley

    Cláudio J Maia

  49. Evaluation of MutS and Mut+ Pichia pastoris Strains for Membrane-Bound Catechol-O-Methyltransferase Biosynthesis

    Article • Applied Biochemistry and Biotechnology, February 2015, Springer Science + Business Media

    Cláudio J Maia

  50. Biochemical Properties of Amniotic Membrane

    Article • January 2015, Springer Science + Business Media

    Cláudio J Maia

  51. Histopathological and in vivo evidence of regucalcin as a protective molecule in mammary gland carcinogenesis

    Article • Experimental Cell Research, January 2015, Elsevier

    Cláudio J Maia, Professor Fernando Schmitt

  52. Hormonal regulation of c-KIT receptor and its ligand: implications for human infertility?

    Article • Progress in Histochemistry and Cytochemistry, September 2014, Elsevier

    Cláudio J Maia

  53. Trends in Protein-Based Biosensor Assemblies for Drug Screening and Pharmaceutical Kinetic Studies

    Article • Molecules, August 2014, MDPI AG

    Cláudio J Maia

  54. Evaluation of the prebiotic potential of arabinoxylans from brewer’s spent grain

    Article • Applied Microbiology and Biotechnology, August 2014, Springer Science + Business Media

    Cláudio J Maia

  55. 752: Anti-cancer proteins found in amniotic membrane: extraction, identification and cellular effects

    Article • European Journal of Cancer, July 2014, Elsevier

    Cláudio J Maia

  56. 750: Human amniotic membrane secreted factors plus chemotherapy: A mishmash of effects?

    Article • European Journal of Cancer, July 2014, Elsevier

    Cláudio J Maia

  57. Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways

    Article • The Prostate, June 2014, Wiley

    Cláudio J Maia

  58. Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms

    Article • Genes & Cancer, June 2014, Impact Journals, LLC

    Cláudio J Maia

  59. Improved Minicircle DNA Biosynthesis for Gene Therapy Applications

    Article • Human Gene Therapy Methods, April 2014, Mary Ann Liebert Inc

    Cláudio J Maia

  60. Effect of Amniotic Membrane Proteins in Human Cancer Cell Lines: An Exploratory Study

    Article • The Journal of Membrane Biology, February 2014, Springer Science + Business Media

    Cláudio J Maia, Mafalda Laranjo

  61. STEAP1 is overexpressed in prostate cancer and prostatic intraepithelial neoplasia lesions, and it is positively associated with Gleason score

    Article • Urologic Oncology Seminars and Original Investigations, January 2014, Elsevier

    Cláudio J Maia

  62. Pichia pastoris: A Recombinant Microfactory for Antibodies and Human Membrane Proteins

    Article • Journal of Microbiology and Biotechnology, May 2013, Korean Society for Microbiology and Biotechnology

    Cláudio J Maia

  63. The diverse roles of calcium-binding protein regucalcin in cell biology: from tissue expression and signalling to disease

    Article • Cellular and Molecular Life Sciences, March 2013, Springer Science + Business Media

    Cláudio J Maia

  64. Long- and short-term effects of androgens in human umbilical artery smooth muscle

    Article • Clinical and Experimental Pharmacology and Physiology, February 2013, Wiley

    Cláudio J Maia

  65. Beyond the Limits of Oxygen: Effects of Hypoxia in a Hormone-Independent Prostate Cancer Cell Line

    Article • ISRN Oncology, January 2013, Hindawi Publishing Corporation

    Cláudio J Maia, Ana Cristina Gonçalves

  66. Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile

    Article • The International Journal of Biochemistry & Cell Biology, November 2012, Elsevier

    Cláudio J Maia, Professor Paula I. Moreira

  67. Six transmembrane epithelial antigen of the prostate 1 is down-regulated by sex hormones in prostate cells

    Article • The Prostate, October 2012, Wiley

    Cláudio J Maia

  68. A new strategy for RNA isolation from eukaryotic cells using arginine affinity chromatography

    Article • Journal of Separation Science, September 2012, Wiley

    Cláudio J Maia

  69. 172 Expression of Apoptosis and Cell-cycle Regulators in Rat Prostate Overexpressing Regucalcin

    Article • European Journal of Cancer, July 2012, Elsevier

    Cláudio J Maia

  70. 177 Effect of Androgens on the Expression of Ca2+-binding Protein, Regucalcin, and Ca2+-channels in MCF-7 Cells

    Article • European Journal of Cancer, July 2012, Elsevier

    Cláudio J Maia

  71. 179 Regulation of STEAP1 Expression in Prostate by Sex Steroid Hormones

    Article • European Journal of Cancer, July 2012, Elsevier

    Cláudio J Maia

  72. Amniotic membrane: from structure and functions to clinical applications

    Article • Cell and Tissue Research, May 2012, Springer Science + Business Media

    Cláudio J Maia, Mafalda Laranjo

  73. STEAP Proteins: From Structure to Applications in Cancer Therapy

    Article • Molecular Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Cláudio J Maia

  74. A novel prokaryotic expression system for biosynthesis of recombinant human membrane-bound catechol-O-methyltransferase

    Article • Journal of Biotechnology, November 2011, Elsevier

    Cláudio J Maia

  75. Impact of plasmid induction strategy on overall plasmid DNA yield and E. coli physiology using flow cytometry and real-time PCR

    Article • Process Biochemistry, January 2011, Elsevier

    Cláudio J Maia

  76. Monitoring plasmid DNA induction strategies using multi-parameter flow cytometry and real-time PCR

    Article • Journal of Biotechnology, November 2010, Elsevier

    Cláudio J Maia

  77. Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones

    Article • Journal of Cellular Biochemistry, July 2009, Wiley

    Cláudio J Maia, Professor Fernando Schmitt

  78. STEAP1 is over-expressed in breast cancer and down-regulated by 17β-estradiol in MCF-7 cells and in the rat mammary gland

    Article • Endocrine, October 2008, Springer Science + Business Media

    Cláudio J Maia, Professor Fernando Schmitt

  79. Characterization of oligoadenylate synthetase-1 expression in rat mammary gland and prostate: effects of 17β-estradiol on the regulation of OAS1g in both tissues

    Article • Molecular and Cellular Biochemistry, April 2008, Springer Science + Business Media

    Cláudio J Maia, Professor Fernando Schmitt

  80. Regucalcin is expressed in rat mammary gland and prostate and down-regulated by 17β-estradiol

    Article • Molecular and Cellular Biochemistry, December 2007, Springer Science + Business Media

    Cláudio J Maia, Professor Fernando Schmitt