All Stories

  1. Glycolysis Inhibition as a Strategy for Hepatocellular Carcinoma Treatment?

    Article • Current Cancer Drug Targets, December 2018, Bentham Science Publishers

    Dr Marco G Alves, Cláudio J Maia, Andreia Alves

  2. Knockdown of STEAP1 inhibits cell growth and induces apoptosis in LNCaP prostate cancer cells counteracting the effect of androgens

    Article • Cancer Immunology Immunotherapy, February 2018, Springer Science + Business Media

    Cláudio J Maia

  3. Targeting STEAP1 Protein in Human Cancer: Current Trends and Future Challenges

    Article • Current Cancer Drug Targets, February 2018, Bentham Science Publishers

    Cláudio J Maia

  4. Variability of MMP/TIMP and TGF-β1 Receptors throughout the Clinical Progression of Chronic Venous Disease

    Article • International Journal of Molecular Sciences, December 2017, MDPI AG

    Cláudio J Maia

  5. The stem cell factor (SCF)/c-KIT system in carcinogenesis of reproductive tissues: What does the hormonal regulation tell us?

    Article • Cancer Letters, October 2017, Elsevier

    Cláudio J Maia

  6. The protective effect of regucalcin against radiation-induced damage in testicular cells

    Article • Life Sciences, November 2016, Elsevier

    Cláudio J Maia

  7. The Emerging Role of Regucalcin as a Tumor Suppressor: Facts and Views

    Article • Current Molecular Medicine, September 2016, Bentham Science Publishers

    Dr Sílvia Socorro, Cláudio J Maia

  8. Endogenous Factors in the Recovery of Reproductive Function After Testicular Injury and Cancer

    Article • Current Molecular Medicine, September 2016, Bentham Science Publishers

    Cláudio J Maia

  9. Liver diseases: what is known so far about the therapy with human amniotic membrane?

    Article • Cell and Tissue Banking, August 2016, Springer Science + Business Media

    Cláudio J Maia, Mafalda Laranjo

  10. Effect of TGF-beta1 on MMP/TIMP and TGF-beta1 receptors in great saphenous veins and its significance on chronic venous insufficiency

    Article • Phlebology The Journal of Venous Disease, June 2016, SAGE Publications

    Cláudio J Maia, Pedro Serralheiro

  11. Oligoadenylate synthetase 1 (OAS1) expression in human breast and prostate cancer cases, and its regulation by sex steroid hormones

    Article • Advances in Modern Oncology Research, June 2016, PiscoMed Publishing Pte Ltd

    Cláudio J Maia

  12. Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug Resistance Proteins: Targets of Human Amniotic Membrane in Hepatocellular Carcinoma

    Article • Pathology & Oncology Research, March 2016, Springer Science + Business Media

    Cláudio J Maia, Mafalda Laranjo

  13. Advances in time course extracellular production of human pre-miR-29b from Rhodovulum sulfidophilum

    Article • Applied Microbiology and Biotechnology, February 2016, Springer Science + Business Media

    Cláudio J Maia

  14. Estrogens down-regulate the stem cell factor (SCF)/c-KIT system in prostate cells: Evidence of antiproliferative and proapoptotic effects

    Article • Biochemical Pharmacology, January 2016, Elsevier

    Cláudio J Maia

  15. Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin

    Article • Translational Research, December 2015, Elsevier

    Cláudio J Maia

  16. Suppressed glycolytic metabolism in the prostate of transgenic rats overexpressing calcium-binding protein regucalcin underpins reduced cell proliferation

    Article • Transgenic Research, November 2015, Springer Science + Business Media

    Cláudio J Maia

  17. Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma

    Article • Cancer Immunology Immunotherapy, October 2015, Springer Science + Business Media

    Ana Cristina Gonçalves, Cláudio J Maia, Mafalda Laranjo

  18. Effect of extracellular calcium on regucalcin expression and cell viability in neoplastic and non-neoplastic human prostate cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 2015, Elsevier

    Cláudio J Maia

  19. 5α-Dihydrotestosterone regulates the expression of L-type calcium channels and calcium-binding protein regucalcin in human breast cancer cells with suppression of cell growth

    Article • Cancer Immunology Immunotherapy, August 2015, Springer Science + Business Media

    Cláudio J Maia

  20. Androgens enhance the glycolytic metabolism and lactate export in prostate cancer cells by modulating the expression of GLUT1, GLUT3, PFK, LDH and MCT4 genes

    Article • Journal of Cancer Research and Clinical Oncology, June 2015, Springer Science + Business Media

    Cláudio J Maia

  21. Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer

    Article • The Prostate, March 2015, Wiley

    Cláudio J Maia

  22. Evaluation of MutS and Mut+ Pichia pastoris Strains for Membrane-Bound Catechol-O-Methyltransferase Biosynthesis

    Article • Applied Biochemistry and Biotechnology, February 2015, Springer Science + Business Media

    Cláudio J Maia

  23. Biochemical Properties of Amniotic Membrane

    Article • January 2015, Springer Science + Business Media

    Cláudio J Maia

  24. Histopathological and in vivo evidence of regucalcin as a protective molecule in mammary gland carcinogenesis

    Article • Experimental Cell Research, January 2015, Elsevier

    Cláudio J Maia, Professor Fernando Schmitt

  25. Hormonal regulation of c-KIT receptor and its ligand: implications for human infertility?

    Article • Progress in Histochemistry and Cytochemistry, September 2014, Elsevier

    Cláudio J Maia

  26. Trends in Protein-Based Biosensor Assemblies for Drug Screening and Pharmaceutical Kinetic Studies

    Article • Molecules, August 2014, MDPI AG

    Cláudio J Maia

  27. Evaluation of the prebiotic potential of arabinoxylans from brewer’s spent grain

    Article • Applied Microbiology and Biotechnology, August 2014, Springer Science + Business Media

    Cláudio J Maia

  28. Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways

    Article • The Prostate, June 2014, Wiley

    Cláudio J Maia

  29. Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms

    Article • Genes & Cancer, June 2014, Impact Journals, LLC

    Cláudio J Maia

  30. Improved Minicircle DNA Biosynthesis for Gene Therapy Applications

    Article • Human Gene Therapy Methods, April 2014, Mary Ann Liebert Inc

    Cláudio J Maia

  31. Effect of Amniotic Membrane Proteins in Human Cancer Cell Lines: An Exploratory Study

    Article • The Journal of Membrane Biology, February 2014, Springer Science + Business Media

    Cláudio J Maia, Mafalda Laranjo

  32. STEAP1 is overexpressed in prostate cancer and prostatic intraepithelial neoplasia lesions, and it is positively associated with Gleason score

    Article • Urologic Oncology Seminars and Original Investigations, January 2014, Elsevier

    Cláudio J Maia

  33. Pichia pastoris: A Recombinant Microfactory for Antibodies and Human Membrane Proteins

    Article • Journal of Microbiology and Biotechnology, May 2013, Korean Society for Microbiology and Biotechnology

    Cláudio J Maia

  34. The diverse roles of calcium-binding protein regucalcin in cell biology: from tissue expression and signalling to disease

    Article • Cellular and Molecular Life Sciences, March 2013, Springer Science + Business Media

    Cláudio J Maia

  35. Long- and short-term effects of androgens in human umbilical artery smooth muscle

    Article • Clinical and Experimental Pharmacology and Physiology, February 2013, Wiley

    Cláudio J Maia

  36. Beyond the Limits of Oxygen: Effects of Hypoxia in a Hormone-Independent Prostate Cancer Cell Line

    Article • ISRN Oncology, January 2013, Hindawi Publishing Corporation

    Cláudio J Maia, Ana Cristina Gonçalves

  37. Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile

    Article • The International Journal of Biochemistry & Cell Biology, November 2012, Elsevier

    Cláudio J Maia, Professor Paula I. Moreira

  38. Six transmembrane epithelial antigen of the prostate 1 is down-regulated by sex hormones in prostate cells

    Article • The Prostate, October 2012, Wiley

    Cláudio J Maia

  39. A new strategy for RNA isolation from eukaryotic cells using arginine affinity chromatography

    Article • Journal of Separation Science, September 2012, Wiley

    Cláudio J Maia

  40. Amniotic membrane: from structure and functions to clinical applications

    Article • Cell and Tissue Research, May 2012, Springer Science + Business Media

    Cláudio J Maia, Mafalda Laranjo

  41. STEAP Proteins: From Structure to Applications in Cancer Therapy

    Article • Molecular Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Cláudio J Maia

  42. A novel prokaryotic expression system for biosynthesis of recombinant human membrane-bound catechol-O-methyltransferase

    Article • Journal of Biotechnology, November 2011, Elsevier

    Cláudio J Maia

  43. Impact of plasmid induction strategy on overall plasmid DNA yield and E. coli physiology using flow cytometry and real-time PCR

    Article • Process Biochemistry, January 2011, Elsevier

    Cláudio J Maia

  44. Monitoring plasmid DNA induction strategies using multi-parameter flow cytometry and real-time PCR

    Article • Journal of Biotechnology, November 2010, Elsevier

    Cláudio J Maia

  45. Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones

    Article • Journal of Cellular Biochemistry, July 2009, Wiley

    Cláudio J Maia, Professor Fernando Schmitt

  46. STEAP1 is over-expressed in breast cancer and down-regulated by 17β-estradiol in MCF-7 cells and in the rat mammary gland

    Article • Endocrine, October 2008, Springer Science + Business Media

    Cláudio J Maia, Professor Fernando Schmitt

  47. Characterization of oligoadenylate synthetase-1 expression in rat mammary gland and prostate: effects of 17β-estradiol on the regulation of OAS1g in both tissues

    Article • Molecular and Cellular Biochemistry, April 2008, Springer Science + Business Media

    Cláudio J Maia, Professor Fernando Schmitt

  48. Regucalcin is expressed in rat mammary gland and prostate and down-regulated by 17β-estradiol

    Article • Molecular and Cellular Biochemistry, December 2007, Springer Science + Business Media

    Cláudio J Maia, Professor Fernando Schmitt