All Stories

  1. Proteasomal and lysosomal clearance of misfolded proteins from the endoplasmic reticulum

    Article • Critical Reviews in Biochemistry and Molecular Biology, March 2019, Taylor & Francis

    Maurizio Molinari

  2. The reductase TMX1 contributes to ERAD by preferentially acting on membrane-associated folding-defective polypeptides

    Article • Biochemical and Biophysical Research Communications, September 2018, Elsevier

    Maurizio Molinari

  3. ER ‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport

    Article • The EMBO Journal, August 2018, EMBO

    Maurizio Molinari

  4. Three branches to rule them all? UPR signalling in response to chemically versus misfolded proteins-induced ER stress

    Article • Biology of the Cell, July 2018, Wiley

    Maurizio Molinari

  5. Eat it right: ER-phagy and recovER-phagy

    Article • Biochemical Society Transactions, May 2018, Portland Press Ltd.

    Maurizio Molinari

  6. Endoplasmic reticulum turnover

    Article • F1000Research, April 2018, Faculty of 1000, Ltd.

    Maurizio Molinari

  7. Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides

    Article • Journal of Biological Chemistry, February 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  8. ER-phagy and recovER-phag: SEC62-mediated endoplasmic reticulum turnover on recovery from ER stress

    Article • Nature Cell Biology, October 2016, Springer Science + Business Media

    Maurizio Molinari, Prof Martin Jung

  9. Five Questions (with their Answers) on ER-Associated Degradation

    Article • Traffic, February 2016, Wiley

    Maurizio Molinari

  10. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang

  11. Quality control mechanisms of protein biogenesis: proteostasis dies hard

    Article • AIMS Biophysics, January 2016, American Institute of Mathematical Sciences (AIMS)

    Maurizio Molinari

  12. Division of labor among oxidoreductases: TMX1 preferentially acts on transmembrane polypeptides

    Article • Molecular Biology of the Cell, October 2015, American Society for Cell Biology (ASCB)

    Maurizio Molinari

  13. The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein

    Article • Journal of Biological Chemistry, July 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  14. Glycoprotein maturation and quality control

    Article • Seminars in Cell and Developmental Biology, May 2015, Elsevier

    Maurizio Molinari

  15. N-linked sugar-regulated protein folding and quality control in the ER

    Article • Seminars in Cell and Developmental Biology, May 2015, Elsevier

    Maurizio Molinari

  16. A novel UGGT1 and p97-dependent checkpoint for native ectodomains with ionizable intramembrane residue

    Article • Molecular Biology of the Cell, April 2015, American Society for Cell Biology (ASCB)

    Maurizio Molinari

  17. Correction for Noack et al., How Viruses Hijack the ERAD Tuning Machinery

    Article • Journal of Virology, March 2015, ASM Journals

    Maurizio Molinari

  18. Proteostasis: Bad news and good news from the endoplasmic reticulum

    Article • Swiss Medical Weekly, August 2014, EMH Swiss Medical Publishers, Ltd.

    Maurizio Molinari

  19. How Viruses Hijack the ERAD Tuning Machinery

    Article • Journal of Virology, July 2014, ASM Journals

    Maurizio Molinari

  20. Non-Lipidated LC3 is Essential for Mouse Hepatitis Virus Infection

    Article • January 2014, Elsevier

    Maurizio Molinari

  21. Transgenic expression of β1 antibody in brain neurons impairs age-dependent amyloid deposition in APP23 mice

    Article • Neurobiology of Aging, December 2013, Elsevier

    Maurizio Molinari

  22. UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum

    Article • Molecular Biology of the Cell, September 2013, American Society for Cell Biology (ASCB)

    Maurizio Molinari

  23. Specificity and Regulation of the Endoplasmic Reticulum-Associated Degradation Machinery

    Article • Traffic, April 2013, Wiley

    Maurizio Molinari

  24. Unconventional roles of nonlipidated LC3 in ERAD tuning and coronavirus infection

    Article • Autophagy, October 2012, Taylor & Francis

    Maurizio Molinari

  25. Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis

    Article • Trends in Biochemical Sciences, October 2012, Elsevier

    Maurizio Molinari

  26. Chronic Delivery of Antibody Fragments Using Immunoisolated Cell Implants as a Passive Vaccination Tool

    Article • PLoS ONE, April 2011, PLOS

    Maurizio Molinari

  27. ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER

    Article • Current Opinion in Cell Biology, April 2011, Elsevier

    Maurizio Molinari

  28. Malectin Participates in a Backup Glycoprotein Quality Control Pathway in the Mammalian ER

    Article • PLoS ONE, January 2011, PLOS

    Maurizio Molinari

  29. Autophagy-independent LC3 function in vesicular traffic

    Article • Autophagy, October 2010, Taylor & Francis

    Maurizio Molinari

  30. Cyclosporine A-Sensitive, Cyclophilin B-Dependent Endoplasmic Reticulum-Associated Degradation

    Article • PLoS ONE, September 2010, PLOS

    Maurizio Molinari

  31. Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication

    Article • Cell Host & Microbe, June 2010, Elsevier

    Maurizio Molinari

  32. N-glycan structures: recognition and processing in the ER

    Article • Trends in Biochemical Sciences, February 2010, Elsevier

    Maurizio Molinari

  33. Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LSsubstrates

    Article • The Journal of Cell Biology, January 2010, Rockefeller University Press

    Maurizio Molinari

  34. Consequences of Individual N-glycan Deletions and of Proteasomal Inhibition on Secretion of Active BACE

    Article • Molecular Biology of the Cell, October 2008, American Society for Cell Biology (ASCB)

    Maurizio Molinari

  35. Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities

    Article • Biochemical and Biophysical Research Communications, July 2008, Elsevier

    Maurizio Molinari

  36. A Dual Task for the Xbp1-responsive OS-9 Variants in the Mammalian Endoplasmic Reticulum

    Article • Journal of Biological Chemistry, April 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  37. The Endoplasmic Reticulum: Crossroads for Newly Synthesized Polypeptide Chains

    Article • January 2008, Elsevier

    Maurizio Molinari

  38. In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human Diseases

    Article • Physiological Reviews, October 2007, American Physiological Society

    Maurizio Molinari

  39. Substrate-Specific Requirements for UGT1-Dependent Release from Calnexin

    Article • Molecular Cell, July 2007, Elsevier

    Maurizio Molinari

  40. N-glycan structure dictates extension of protein folding or onset of disposal

    Article • Nature Chemical Biology, May 2007, Springer Science + Business Media

    Maurizio Molinari

  41. Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins

    Article • FEBS Letters, May 2007, Wiley

    Maurizio Molinari

  42. N-glycan processing in ER quality control

    Article • Journal of Cell Science, November 2006, The Company of Biologists

    Maurizio Molinari

  43. Microbiology: Death of a chaperone

    Article • Nature, October 2006, Springer Science + Business Media

    prof cesare montecucco, Maurizio Molinari

  44. N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control

    Article • Current Opinion in Structural Biology, October 2006, Elsevier

    Maurizio Molinari

  45. Consequences of ERp57 Deletion on Oxidative Folding of Obligate and Facultative Clients of the Calnexin Cycle

    Article • Journal of Biological Chemistry, January 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  46. The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags

    Article • Trends in Cell Biology, July 2005, Elsevier

    Maurizio Molinari

  47. The Use of Calnexin and Calreticulin by Cellular and Viral Glycoproteins

    Article • Journal of Biological Chemistry, June 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  48. Degradation of Trafficking-defective Long QT Syndrome Type II Mutant Channels by the Ubiquitin-Proteasome Pathway

    Article • Journal of Biological Chemistry, March 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  49. Analyzing folding and degradation of metabolically labelled polypeptides by conventional and diagonal sodium dodecyl sulfate-polyacrylamide gel electrophoresis

    Article • Biological Procedures Online, January 2005, Springer Science + Business Media

    Maurizio Molinari

  50. A Novel Stress-induced EDEM Variant Regulating Endoplasmic Reticulum-associated Glycoprotein Degradation

    Article • Journal of Biological Chemistry, December 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  51. EDEM Contributes to Maintenance of Protein Folding Efficiency and Secretory Capacity

    Article • Journal of Biological Chemistry, August 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  52. Contrasting Functions of Calreticulin and Calnexin in Glycoprotein Folding and ER Quality Control

    Article • Molecular Cell, January 2004, Elsevier

    Maurizio Molinari

  53. Role of EDEM in the Release of Misfolded Glycoproteins from the Calnexin Cycle

    Article • Science, February 2003, American Association for the Advancement of Science

    Maurizio Molinari

  54. Early Postnatal Death and Motor Disorders in Mice Congenitally Deficient in Calnexin Expression

    Article • Molecular and Cellular Biology, November 2002, ASM Journals

    Maurizio Molinari

  55. The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity

    Article • Journal of Neurochemistry, March 2002, Wiley

    Maurizio Molinari

  56. [4] Analyzing cotranslational protein folding and disulfide formation by diagonal sodium dodecyl sulfate-polyacrylamide gel electrophoresis

    Article • January 2002, Elsevier

    Professor Huangen Ding, Maurizio Molinari

  57. Folding of viral glycoproteins in the endoplasmic reticulum

    Article • Virus Research, December 2001, Elsevier

    Maurizio Molinari

  58. Chaperone Selection During Glycoprotein Translocation into the Endoplasmic Reticulum

    Article • Science, April 2000, American Association for the Advancement of Science

    Maurizio Molinari

  59. Setting the Standards: Quality Control in the Secretory Pathway

    Article • Science, December 1999, American Association for the Advancement of Science

    Lars Ellgaard, Maurizio Molinari

  60. Glycoproteins form mixed disulphides with oxidoreductases during folding in living cells

    Article • Nature, November 1999, Springer Science + Business Media

    Maurizio Molinari

  61. The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structure

    Article • Molecular Microbiology, October 1999, Wiley

    Maurizio Molinari

  62. Calpain: A Protease in Search of a Function?

    Article • Biochemical and Biophysical Research Communications, August 1998, Elsevier

    Maurizio Molinari

  63. The Acid Activation ofHelicobacter pyloriToxin VacA: Structural and Membrane Binding Studies

    Article • Biochemical and Biophysical Research Communications, July 1998, Elsevier

    Professor Marina de Bernard, Maurizio Molinari

  64. Calpain: A Protease in Search of a Function?

    Article • Biochemical and Biophysical Research Communications, June 1998, Elsevier

    Maurizio Molinari

  65. Selective Inhibition of Ii-dependent Antigen Presentation byHelicobacter pyloriToxin VacA

    Article • The Journal of Experimental Medicine, January 1998, Rockefeller University Press

    Dr Mariolina Salio, Maurizio Molinari

  66. Calpain: A Cytosolic Proteinase Active at the Membranes

    Article • The Journal of Membrane Biology, March 1997, Springer Science + Business Media

    Maurizio Molinari

  67. Purification of μ-Calpain by a Novel Affinity Chromatography Approach. NEW INSIGHTS INTO THE MECHANISM OF THE INTERACTION OF THE PROTEASE WITH TARGETS

    Article • Journal of Biological Chemistry, June 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari

  68. PEST Sequences Do Not Influence Substrate Susceptibility to Calpain Proteolysis

    Article • Journal of Biological Chemistry, February 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Maurizio Molinari