What is it about?

We report in this exhaustive review what is known in the litterature abouts vitamin E oxidation products (VEOP). We describe the different oxidative pathways and the chemical reaction responsible for VEOP production. We report also what is known about the biological propeties of these VEOP. These VEOP as well as vitamin E metabolites constitute the "VitaminEome".

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Why is it important?

Vitamin E are proposed as antioxidant in dietary supplements to prevent against various diseases. Because they are very potent antioxidant, they are rapidly transformed in our body into VEOP. Their biological properties has been poorly studied, and deserve further investigations.

Perspectives

Vitamin E components can give oxidation products which biological and toxicological properties deserve further investigations.

Dr Marc Etienne Poirot
Cancer Research Center of Toulouse UMR 1037 Inserm-university of Toulouse, France

Read the Original

This page is a summary of: In vitro and In vivo oxidation and cleavage products of tocols: From chemical tuners to “VitaminEome” therapeutics. A narrative review, Food Bioscience, October 2022, Elsevier,
DOI: 10.1016/j.fbio.2022.101839.
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