All Stories

  1. Databases of liquid–liquid phase separation proteins and condensates

    Article • Current Opinion in Structural Biology, October 2026, Elsevier

    Salvador Ventura

  2. AggrescanAI: Prediction of Aggregation-Prone Regions Using Contextualized Embeddings

    Article • Journal of Molecular Biology, September 2026, Elsevier

    Salvador Ventura

  3. Peptideins: Navigating the gray zone of the proteome

    Article • Trends in Biochemical Sciences, September 2026, Elsevier

    Salvador Ventura

  4. Integrated computational identification of natural product-derived candidates targeting the bicalutamide-resistant W741L androgen receptor in castration-resistant prostate cancer

    Article • Intelligent Pharmacy, July 2026, Elsevier

    Salvador Ventura

  5. Can we vaccinate the brain? The promise of precision immunology

    Article • The Biochemist, May 2026, Portland Press Ltd.

    Salvador Ventura

  6. Full-Length Molecular Models of Brain-Derived α-Synuclein Fibrils Reveal a Fuzzy-Coat-Mediated Mechanism for Selective Peptide Binding

    Article • April 2026, openRxiv

    Salvador Ventura

  7. Passive immunotherapy for Parkinson’s disease in 2025: Status and perspective

    Article • Neural Regeneration Research, January 2026, Wolters Kluwer Health

    Salvador Ventura

  8. AGGRESCAN and its evolution: A two-decade perspective on protein aggregation prediction

    Article • Biophysical Reviews, January 2026, Springer Science + Business Media

    Salvador Ventura

  9. Computational Characterization of Pathogenic LMNA Missense Variants: Structural Instability, Altered Binding, and Conformational Dynamics

    Article • Human Mutation, January 2026, Wiley

    Salvador Ventura

  10. Recent cryo-EM structures redefine the functional amyloid landscape

    Article • January 2026, Elsevier

    Salvador Ventura

  11. Mass spectrometry reveals transthyretin shape shifts to guide better amyloidosis drugs

    Article • Proceedings of the National Academy of Sciences, December 2025, Proceedings of the National Academy of Sciences

    Salvador Ventura

  12. Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

    Article • Advanced Healthcare Materials, October 2025, Wiley

    Salvador Ventura

  13. LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson’s disease model

    Article • Communications Biology, August 2025, Springer Science + Business Media

    Salvador Ventura

  14. Comprehensive protein datasets and benchmarking for liquid–liquid phase separation studies

    Article • Genome Biology, July 2025, Springer Science + Business Media

    Salvador Ventura

  15. Experimental kinetic mechanism of P53 condensation-amyloid aggregation

    Article • Biophysical Journal, May 2025, Elsevier

    Salvador Ventura

  16. Harnessing the immune system: vaccines to fight neurodegenerative diseases

    Article • Trends in Molecular Medicine, March 2025, Elsevier

    Salvador Ventura

  17. MIA40 circumvents the folding constraints imposed by TRIAP1 function

    Article • Journal of Biological Chemistry, March 2025, Elsevier

    Salvador Ventura

  18. Determinants of alpha-synuclein pathogenesis in Parkinson’s disease

    Article • Neural Regeneration Research, February 2025, Wolters Kluwer Health

    Salvador Ventura

  19. Structural commonalities determined by physicochemical principles in the complex polymorphism of the amyloid state of proteins

    Article • Biochemical Journal, January 2025, Portland Press Ltd.

    Professor Michele Vendruscolo, Salvador Ventura

  20. Identification of α-Synuclein Aggregation Inhibitors via High-Throughput Screening

    Article • December 2024, Springer Science + Business Media

    Salvador Ventura

  21. The role of amphipathic and cationic helical peptides in Parkinson's disease

    Article • Protein Science, December 2024, Wiley

    Salvador Ventura

  22. The dual nature of amyloids: From pathogenic aggregates to functional biostructures

    Article • The Biochemist, December 2024, Portland Press Ltd.

    Salvador Ventura

  23. Building Up Functional Coiled-Coil-Based Supramolecular Assemblies for Biomedical and Biotechnological Applications

    Article • November 2024, Springer Science + Business Media

    Salvador Ventura

  24. Bioengineered self-assembled nanofibrils for high-affinity SARS-CoV-2 capture and neutralization

    Article • Journal of Colloid and Interface Science, November 2024, Elsevier

    Salvador Ventura

  25. Aggregating amyloid resources: A comprehensive review of databases on amyloid-like aggregation

    Article • Computational and Structural Biotechnology Journal, October 2024, American Association for the Advancement of Science

    Salvador Ventura

  26. The small molecule ZPD ‐2 inhibits the aggregation and seeded polymerisation of C‐terminally truncated α‐Synuclein

    Article • FEBS Journal, October 2024, Wiley

    Salvador Ventura

  27. Protein Nanoparticles for Targeted SARS‐CoV‐2 Trapping and Neutralization

    Article • Advanced Healthcare Materials, October 2024, Wiley

    Salvador Ventura

  28. Exploitation of the nitro- and/or 4-Trifluoromethyl-decorated phenyl fragment to develop small inhibitors of Alpha-Syn fibril aggregation

    Article • Bioorganic & Medicinal Chemistry Letters, October 2024, Elsevier

    Salvador Ventura

  29. Aggrescan4D: A comprehensive tool for pH‐dependent analysis and engineering of protein aggregation propensity

    Article • Protein Science, September 2024, Wiley

    Salvador Ventura

  30. Beyond neurodegeneration: engineering amyloids for biocatalysis

    Article • Neural Regeneration Research, September 2024, Wolters Kluwer Health

    Salvador Ventura

  31. Structural information in therapeutic peptides: Emerging applications in biomedicine

    Article • FEBS Open Bio, June 2024, Wiley

    Salvador Ventura

  32. Design and redesign journey of a drug for transthyretin amyloidosis

    Article • Neural Regeneration Research, June 2024, Wolters Kluwer Health

    Salvador Ventura

  33. Gut microbiota produces biofilm-associated amyloids with potential for neurodegeneration

    Article • Nature Communications, May 2024, Springer Science + Business Media

    Salvador Ventura

  34. Aggrescan4D: structure-informed analysis of pH-dependent protein aggregation

    Article • Nucleic Acids Research, May 2024, Oxford University Press (OUP)

    Salvador Ventura

  35. An α-helical peptide-based plasmonic biosensor for highly specific detection of α-synuclein toxic oligomers

    Article • Analytica Chimica Acta, May 2024, Elsevier

    Salvador Ventura

  36. A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion

    Article • Journal of the American Chemical Society, April 2024, American Chemical Society (ACS)

    Salvador Ventura

  37. Mutations in human prion-like domains: pathogenic but not always amyloidogenic

    Article • Prion, March 2024, Taylor & Francis

    Salvador Ventura

  38. Effect of the aggregated protein dye YAT2150 on Leishmania parasite viability

    Article • Antimicrobial Agents and Chemotherapy, March 2024, ASM Journals

    Salvador Ventura

  39. Protein-only Nanoparticles for T Cell Expansion and Activation

    Article • ACS Applied Nano Materials, February 2024, American Chemical Society (ACS)

    Salvador Ventura

  40. Advances, challenges, and opportunities in structural biology

    Article • Trends in Biochemical Sciences, February 2024, Elsevier

    Salvador Ventura

  41. Cryo-EM structures of functional and pathological amyloid ribonucleoprotein assemblies

    Article • Trends in Biochemical Sciences, February 2024, Elsevier

    Salvador Ventura

  42. Harnessing prion-inspired amyloid self-assembly for sustainable and biocompatible proton conductivity

    Article • Nanoscale Advances, January 2024, Royal Society of Chemistry

    Salvador Ventura

  43. Assembly and catalytic activity of short prion-inspired peptides

    Article • January 2024, Elsevier

    Salvador Ventura

  44. Editorial: Molecular determinants of protein assemblies in health and disease, Volume II

    Article • Frontiers in Molecular Biosciences, December 2023, Frontiers

    Salvador Ventura

  45. A glimpse into the structural properties of α‐synuclein oligomers

    Article • BioFactors, December 2023, Wiley

    Salvador Ventura

  46. PITB: A high affinity transthyretin aggregation inhibitor with optimal pharmacokinetic properties

    Article • European Journal of Medicinal Chemistry, December 2023, Elsevier

    Salvador Ventura

  47. Rational optimization of a transcription factor activation domain inhibitor

    Article • Nature Structural & Molecular Biology, December 2023, Springer Science + Business Media

    Salvador Ventura

  48. DisProt in 2024: improving function annotation of intrinsically disordered proteins

    Article • Nucleic Acids Research, October 2023, Oxford University Press (OUP)

    Salvador Ventura

  49. A3D Model Organism Database (A3D-MODB): a database for proteome aggregation predictions in model organisms

    Article • Nucleic Acids Research, October 2023, Oxford University Press (OUP)

    Salvador Ventura

  50. A3DyDB: exploring structural aggregation propensities in the yeast proteome

    Article • Microbial Cell Factories, September 2023, Springer Science + Business Media

    Salvador Ventura

  51. Expanding the Landscape of Amyloid Sequences with CARs-DB: A Database of Polar Amyloidogenic Peptides from Disordered Proteins

    Article • September 2023, Springer Science + Business Media

    Salvador Ventura

  52. Amyloid Fibrils Formed by Short Prion-Inspired Peptides Are Metalloenzymes

    Article • ACS Nano, August 2023, American Chemical Society (ACS)

    Salvador Ventura

  53. Editorial: Peptide assemblies in nanotechnology

    Article • Frontiers in Molecular Biosciences, August 2023, Frontiers

    Salvador Ventura

  54. Chemical targeting of amyloids

    Article • Nature Chemical Biology, July 2023, Springer Science + Business Media

    Salvador Ventura

  55. Small molecules to target tau amyloid aggregation

    Article • Neural Regeneration Research, July 2023, Wolters Kluwer Health

    Salvador Ventura

  56. Arabidopsismetacaspase MC1 localizes in stress granules, clears protein aggregates, and delays senescence

    Article • The Plant Cell, July 2023, Oxford University Press (OUP)

    Salvador Ventura

  57. Development of Small Molecules Targeting α-Synuclein Aggregation: A Promising Strategy to Treat Parkinson’s Disease

    Article • Pharmaceutics, March 2023, MDPI AG

    Salvador Ventura

  58. OligoBinders: Bioengineered Soluble Amyloid-like Nanoparticles to Bind and Neutralize SARS-CoV-2

    Article • ACS Applied Materials & Interfaces, February 2023, American Chemical Society (ACS)

    Salvador Ventura

  59. A targetable N-terminal motif orchestrates α-Synuclein oligomer to fibril conversion

    Article • February 2023, openRxiv

    Salvador Ventura

  60. Author Correction: Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity

    Article • Nature Communications, February 2023, Springer Science + Business Media

    Salvador Ventura

  61. A Review of Fifteen Years Developing Computational Tools to Study Protein Aggregation

    Article • Biophysica, January 2023, MDPI AG

    Salvador Ventura

  62. Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3

    Article • Nature Communications, January 2023, Springer Science + Business Media

    Salvador Ventura

  63. Exploring cryptic amyloidogenic regions in prion-like proteins from plants

    Article • Frontiers in Plant Science, January 2023, Frontiers

    Salvador Ventura

  64. aSynPEP-DB: a database of biogenic peptides for inhibiting α-synuclein aggregation

    Article • Database, January 2023, Oxford University Press (OUP)

    Salvador Ventura

  65. LL-37 and CsgC exemplify the crosstalk between anti-amyloid, antimicrobial, and anti-biofilm protein activities

    Article • Neural Regeneration Research, January 2023, Wolters Kluwer Health

    Salvador Ventura

  66. Editorial: Molecular determinants of protein assemblies in health and disease

    Article • Frontiers in Molecular Biosciences, December 2022, Frontiers

    Salvador Ventura

  67. Ligand-Based Discovery of a Small Molecule as Inhibitor of α-Synuclein Amyloid Formation

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Salvador Ventura

  68. A finely tuned interplay between calcium binding, ionic strength and pH modulates conformational and oligomerization equilibria in the Respiratory Syncytial Virus Matrix (M) protein

    Article • Archives of Biochemistry and Biophysics, November 2022, Elsevier

    Salvador Ventura

  69. Development of a Highly Potent Transthyretin Amyloidogenesis Inhibitor: Design, Synthesis, and Evaluation

    Article • Journal of Medicinal Chemistry, October 2022, American Chemical Society (ACS)

    Salvador Ventura

  70. Cryo-EM Structure of a Mammalian-specific Alternative Amyloid Exon

    Article • August 2022, openRxiv

    Salvador Ventura

  71. Rational optimization of a transcription factor activation domain inhibitor

    Article • August 2022, openRxiv

    Salvador Ventura

  72. Is a cure for Parkinson’s disease hiding inside us?

    Article • Trends in Biochemical Sciences, August 2022, Elsevier

    Salvador Ventura

  73. In-Silico Analysis of pH-Dependent Liquid-Liquid Phase Separation in Intrinsically Disordered Proteins

    Article • Biomolecules, July 2022, MDPI AG

    Salvador Ventura

  74. CARs-DB: A Database of Cryptic Amyloidogenic Regions in Intrinsically Disordered Proteins

    Article • Frontiers in Molecular Biosciences, May 2022, Frontiers

    Salvador Ventura

  75. Correction: Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsis

    Article • PLoS Genetics, May 2022, PLOS

    Salvador Ventura

  76. The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains

    Article • Journal of Biological Chemistry, May 2022, Elsevier

    Salvador Ventura

  77. A3D database: structure-based predictions of protein aggregation for the human proteome

    Article • Bioinformatics, April 2022, Oxford University Press (OUP)

    Salvador Ventura

  78. Computational methods to predict protein aggregation

    Article • Current Opinion in Structural Biology, April 2022, Elsevier

    Salvador Ventura

  79. Discovery of Neuroprotective Agents Based on a 5-(4-Pyridinyl)-1,2,4-triazole Scaffold

    Article • ACS Chemical Neuroscience, February 2022, American Chemical Society (ACS)

    Salvador Ventura

  80. One ring is sufficient to inhibit α-synuclein aggregation

    Article • Neural Regeneration Research, January 2022, Wolters Kluwer Health

    Salvador Ventura

  81. The dynamic landscape of peptide activity prediction

    Article • Computational and Structural Biotechnology Journal, January 2022, American Association for the Advancement of Science

    Salvador Ventura

  82. A3D 2.0 Update for the Prediction and Optimization of Protein Solubility

    Article • January 2022, Springer Science + Business Media

    Salvador Ventura

  83. Prediction of the Effect of pH on the Aggregation and Conditional Folding of Intrinsically Disordered Proteins with SolupHred and DispHred

    Article • January 2022, Springer Science + Business Media

    Salvador Ventura

  84. Protocols for Rational Design of Protein Solubility and Aggregation Properties Using Aggrescan3D Standalone

    Article • January 2022, Springer Science + Business Media

    Salvador Ventura

  85. Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability

    Article • Bioorganic Chemistry, December 2021, Elsevier

    Salvador Ventura

  86. DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation

    Article • Nucleic Acids Research, November 2021, Oxford University Press (OUP)

    Salvador Ventura

  87. A3D Database: Structure-based Protein Aggregation Predictions for the Human Proteome

    Article • November 2021, openRxiv

    Salvador Ventura

  88. DispHScan: A Multi-Sequence Web Tool for Predicting Protein Disorder as a Function of pH

    Article • Biomolecules, October 2021, MDPI AG

    Salvador Ventura

  89. AlphaFold and the amyloid landscape

    Article • Journal of Molecular Biology, October 2021, Elsevier

    Salvador Ventura

  90. Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation

    Article • Journal of Biological Chemistry, September 2021, Elsevier

    Salvador Ventura

  91. Multifunctional antibody-conjugated coiled-coil protein nanoparticles for selective cell targeting

    Article • Acta Biomaterialia, September 2021, Elsevier

    Salvador Ventura

  92. SGnn: A Web Server for the Prediction of Prion-Like Domains Recruitment to Stress Granules Upon Heat Stress

    Article • Frontiers in Molecular Biosciences, August 2021, Frontiers

    Salvador Ventura

  93. Coiled-Coil Based Inclusion Bodies and Their Potential Applications

    Article • Frontiers in Bioengineering and Biotechnology, August 2021, Frontiers

    Salvador Ventura

  94. Functionalized Prion-Inspired Amyloids for Biosensor Applications

    Article • Biomacromolecules, July 2021, American Chemical Society (ACS)

    Salvador Ventura

  95. α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity

    Article • Nature Communications, June 2021, Springer Science + Business Media

    Salvador Ventura

  96. Prion‐like proteins: from computational approaches to proteome‐wide analysis

    Article • FEBS Open Bio, June 2021, Wiley

    Salvador Ventura

  97. Prediction of the effect of pH on the aggregation and conditional folding of intrinsically disordered proteins with SolupHred and DispHred

    Article • June 2021, openRxiv

    Salvador Ventura

  98. Critical assessment of protein intrinsic disorder prediction

    Article • Nature Chemical Biology, April 2021, Springer Science + Business Media

    Dr Sandra Macedo-Ribeiro, Salvador Ventura

  99. A3D 2.0 update for the prediction and optimization of protein solubility

    Article • April 2021, openRxiv

    Salvador Ventura

  100. Prospects for beyond the Standard Model physics searches at the Deep Underground Neutrino Experiment

    Article • The European Physical Journal C, April 2021, Springer Science + Business Media

    Salvador Ventura

  101. MED15 prion-like domain forms a coiled-coil responsible for its amyloid conversion and propagation

    Article • Communications Biology, March 2021, Springer Science + Business Media

    Salvador Ventura

  102. Dual Antibody-Conjugated Amyloid Nanorods to Promote Selective Cell–Cell Interactions

    Article • ACS Applied Materials & Interfaces, March 2021, American Chemical Society (ACS)

    Salvador Ventura

  103. α-Helical peptidic scaffolds to target α-synuclein pathogenic species with high affinity and selectivity

    Article • March 2021, openRxiv

    Salvador Ventura

  104. Pathological ATX3 Expression Induces Cell Perturbations in E. coli as Revealed by Biochemical and Biophysical Investigations

    Article • International Journal of Molecular Sciences, January 2021, MDPI AG

    Salvador Ventura

  105. Cryptic amyloidogenic regions in intrinsically disordered proteins: Function and disease association

    Article • Computational and Structural Biotechnology Journal, January 2021, American Association for the Advancement of Science

    Salvador Ventura

  106. Decoding the role of coiled-coil motifs in human prion-like proteins

    Article • Prion, January 2021, Taylor & Francis

    Salvador Ventura

  107. Functional Amyloids Germinate in Plants

    Article • Trends in Plant Science, January 2021, Elsevier

    Salvador Ventura

  108. pH-Responsive Self-Assembly of Amyloid Fibrils for Dual Hydrolase-Oxidase Reactions

    Article • ACS Catalysis, December 2020, American Chemical Society (ACS)

    Salvador Ventura

  109. Editorial: Protein Aggregation and Solubility in Microorganisms (Archaea, Bacteria and Unicellular Eukaryotes): Implications and Applications

    Article • Frontiers in Microbiology, November 2020, Frontiers

    Salvador Ventura

  110. MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments

    Article • Frontiers in Molecular Neuroscience, November 2020, Frontiers

    Dr Sandra Macedo-Ribeiro, Salvador Ventura

  111. Special Issue: “Inflammation, Oxidative Stress and Protein Aggregation; Any Links?”

    Article • Cells, November 2020, MDPI AG

    Salvador Ventura

  112. SolupHred: a server to predict the pH-dependent aggregation of intrinsically disordered proteins

    Article • Bioinformatics, October 2020, Oxford University Press (OUP)

    Salvador Ventura

  113. Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm

    Article • Frontiers in Bioengineering and Biotechnology, October 2020, Frontiers

    Salvador Ventura

  114. Amyloidogenicity as a driving force for the formation of functional oligomers

    Article • Journal of Structural Biology, October 2020, Elsevier

    Salvador Ventura

  115. Protocols for rational design of protein solubility and aggregation properties using Aggrescan3D standalone

    Article • September 2020, openRxiv

    Salvador Ventura

  116. Multifunctional Amyloid Oligomeric Nanoparticles for Specific Cell Targeting and Drug Delivery

    Article • Biomacromolecules, September 2020, American Chemical Society (ACS)

    Salvador Ventura

  117. DispHred: A Server to Predict pH-Dependent Order–Disorder Transitions in Intrinsically Disordered Proteins

    Article • International Journal of Molecular Sciences, August 2020, MDPI AG

    Salvador Ventura

  118. Reply to Comment on “N-terminal Protein Tail Acts as Aggregation Protective Entropic Bristles: The SUMO Case”

    Article • Biomacromolecules, July 2020, American Chemical Society (ACS)

    Salvador Ventura

  119. Prion-like domain disease-causing mutations and misregulation of alternative splicing relevance in limb-girdle muscular dystrophy (LGMD) 1G

    Article • Neural Regeneration Research, June 2020, Wolters Kluwer Health

    Salvador Ventura

  120. Small molecules to prevent the neurodegeneration caused by α-synuclein aggregation

    Article • Neural Regeneration Research, June 2020, Wolters Kluwer Health

    Salvador Ventura

  121. Coiled-coil inspired functional inclusion bodies

    Article • Microbial Cell Factories, June 2020, Springer Science + Business Media

    Salvador Ventura

  122. Detection of Protein Aggregation in Live Plasmodium Parasites

    Article • Antimicrobial Agents and Chemotherapy, May 2020, ASM Journals

    Salvador Ventura

  123. Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis

    Article • FEBS Journal, May 2020, Wiley

    Salvador Ventura

  124. Chemical Chaperones as Novel Drugs for Parkinson’s Disease

    Article • Trends in Molecular Medicine, April 2020, Elsevier

    Salvador Ventura

  125. Soluble Assemblies in the Fibrillation Pathway of Prion-Inspired Artificial Functional Amyloids are Highly Cytotoxic

    Article • Biomacromolecules, March 2020, American Chemical Society (ACS)

    Salvador Ventura

  126. The biofilm-associated surface protein Esp of Enterococcus faecalis forms amyloid-like fibers

    Article • npj Biofilms and Microbiomes, March 2020, Springer Science + Business Media

    Salvador Ventura

  127. pH-Dependent Aggregation in Intrinsically Disordered Proteins Is Determined by Charge and Lipophilicity

    Article • Cells, January 2020, MDPI AG

    Salvador Ventura

  128. Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications

    Article • Computational and Structural Biotechnology Journal, January 2020, American Association for the Advancement of Science

    Salvador Ventura

  129. Prion domains as a driving force for the assembly of functional nanomaterials

    Article • Prion, January 2020, Taylor & Francis

    Salvador Ventura

  130. Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2020, Taylor & Francis

    Salvador Ventura

  131. Atomistic fibrillar architectures of polar prion-inspired heptapeptides

    Article • Chemical Science, January 2020, Royal Society of Chemistry

    Salvador Ventura

  132. Computational prediction and redesign of aberrant protein oligomerization

    Article • January 2020, Elsevier

    Salvador Ventura

  133. hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation

    Article • Cell Reports, January 2020, Elsevier

    Salvador Ventura

  134. C-Mannosylation supports folding and enhances stability of thrombospondin repeats

    Article • eLife, December 2019, eLife

    Dr Manuel H Taft, Salvador Ventura

  135. ZPD-2, a Small Compound That Inhibits α-Synuclein Amyloid Aggregation and Its Seeded Polymerization

    Article • Frontiers in Molecular Neuroscience, December 2019, Frontiers

    Salvador Ventura

  136. DisProt: intrinsic protein disorder annotation in 2020

    Article • Nucleic Acids Research, November 2019, Oxford University Press (OUP)

    Dr Vasilis J Promponas, Dr Sandra Macedo-Ribeiro, Salvador Ventura

  137. Advances in the Prediction of Protein Aggregation Propensity

    Article • Current Medicinal Chemistry, September 2019, Bentham Science Publishers

    Salvador Ventura

  138. Dual Binding Mode of Metallacarborane Produces a Robust Shield on Proteins

    Article • Chemistry - A European Journal, September 2019, Wiley

    Salvador Ventura

  139. Computational Assessment of Bacterial Protein Structures Indicates a Selection Against Aggregation

    Article • Cells, August 2019, MDPI AG

    Salvador Ventura

  140. Computational re-design of protein structures to improve solubility

    Article • Expert Opinion on Drug Discovery, July 2019, Taylor & Francis

    Salvador Ventura

  141. Aggrescan3D (A3D) 2.0: prediction and engineering of protein solubility

    Article • Nucleic Acids Research, May 2019, Oxford University Press (OUP)

    Salvador Ventura

  142. The fitness cost and benefit of phase‐separated protein deposits

    Article • Molecular Systems Biology, April 2019, EMBO

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot, Salvador Ventura

  143. Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity

    Article • Redox Biology, April 2019, Elsevier

    Salvador Ventura

  144. In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases

    Article • Frontiers in Physiology, March 2019, Frontiers

    Salvador Ventura

  145. The fitness cost and benefit of phase separated protein deposits

    Article • March 2019, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot, Salvador Ventura

  146. Aggrescan3D standalone package for structure-based prediction of protein aggregation properties

    Article • Bioinformatics, March 2019, Oxford University Press (OUP)

    Salvador Ventura

  147. AMYCO: evaluation of mutational impact on prion-like proteins aggregation propensity

    Article • BMC Bioinformatics, January 2019, Springer Science + Business Media

    Salvador Ventura

  148. Prion soft amyloid core driven self-assembly of globular proteins into bioactive nanofibrils

    Article • Nanoscale, January 2019, Royal Society of Chemistry

    Salvador Ventura

  149. Inducing α-synuclein compaction: a new strategy for inhibiting α-synuclein aggregation?

    Article • Neural Regeneration Research, January 2019, Wolters Kluwer Health

    Salvador Ventura

  150. Formation of Cross-Beta Supersecondary Structure by Soft-Amyloid Cores: Strategies for Their Prediction and Characterization

    Article • January 2019, Springer Science + Business Media

    Salvador Ventura

  151. A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aβ1–42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus aureus biofilms

    Article • Analytical and Bioanalytical Chemistry, November 2018, Springer Science + Business Media

    Salvador Ventura

  152. Screening Protein Aggregation in Cells Using Fluorescent Labels Coupled to Flow Cytometry

    Article • October 2018, Springer Science + Business Media

    Salvador Ventura

  153. Prion-based nanomaterials and their emerging applications

    Article • Prion, October 2018, Taylor & Francis

    Salvador Ventura

  154. Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons

    Article • Proceedings of the National Academy of Sciences, September 2018, Proceedings of the National Academy of Sciences

    Salvador Ventura

  155. Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses

    Article • Human Molecular Genetics, September 2018, Oxford University Press (OUP)

    Salvador Ventura

  156. Discovering Putative Prion-Like Proteins in Plasmodium falciparum: A Computational and Experimental Analysis

    Article • Frontiers in Microbiology, August 2018, Frontiers

    Dr Natalia Sanchez de Groot, Salvador Ventura

  157. Protein Environment: A Crucial Triggering Factor in Josephin Domain Aggregation: The Role of 2,2,2-Trifluoroethanol

    Article • International Journal of Molecular Sciences, July 2018, MDPI AG

    Salvador Ventura

  158. Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility

    Article • Molecular Pharmaceutics, July 2018, American Chemical Society (ACS)

    Salvador Ventura

  159. Global Protein Stabilization Does Not Suffice to Prevent Amyloid Fibril Formation

    Article • ACS Chemical Biology, July 2018, American Chemical Society (ACS)

    Salvador Ventura

  160. Evaluation of the Impact of Protein Aggregation on Cellular Oxidative Stress in Yeast

    Article • Journal of Visualized Experiments, June 2018, MyJove Corporation

    Salvador Ventura

  161. Minimalist Prion-Inspired Polar Self-Assembling Peptides

    Article • ACS Nano, May 2018, American Chemical Society (ACS)

    Salvador Ventura

  162. The Disordered C-Terminus of Yeast Hsf1 Contains a Cryptic Low-Complexity Amyloidogenic Region

    Article • International Journal of Molecular Sciences, May 2018, MDPI AG

    Salvador Ventura

  163. A single cysteine post-translational oxidation suffices to compromise globular proteins kinetic stability and promote amyloid formation

    Article • Redox Biology, April 2018, Elsevier

    Salvador Ventura

  164. Molecular and Clinical Aspects of Protein Aggregation Assays in Neurodegenerative Diseases

    Article • Molecular Neurobiology, February 2018, Springer Science + Business Media

    Salvador Ventura

  165. Amyloid Formation in Bacteria

    Article • January 2018, Springer Science + Business Media

    Salvador Ventura

  166. AGGRESCAN3D: Toward the Prediction of the Aggregation Propensities of Protein Structures

    Article • January 2018, Springer Science + Business Media

    Salvador Ventura

  167. Disulfide driven folding for a conditionally disordered protein

    Article • Scientific Reports, December 2017, Springer Science + Business Media

    Salvador Ventura

  168. Characterization of Soft Amyloid Cores in Human Prion-Like Proteins

    Article • Scientific Reports, September 2017, Nature

    Dr Natalia Sanchez de Groot, Salvador Ventura

  169. Protein aggregation into insoluble deposits protects from oxidative stress

    Article • Redox Biology, August 2017, Elsevier

    Dr Natalia Sanchez de Groot, Salvador Ventura

  170. Plasticity in the Oxidative Folding Pathway of the High Affinity Nerita Versicolor Carboxypeptidase Inhibitor (NvCI)

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Salvador Ventura

  171. Perfecting prediction of mutational impact on the aggregation propensity of the ALS‐associated hnRNPA2 prion‐like protein

    Article • FEBS Letters, June 2017, Wiley

    Salvador Ventura

  172. The Transcription Terminator Rho: A First Bacterial Prion

    Article • Trends in Microbiology, June 2017, Elsevier

    Salvador Ventura

  173. Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Salvador Ventura

  174. Prion-like proteins and their computational identification in proteomes

    Article • Expert Review of Proteomics, March 2017, Taylor & Francis

    Salvador Ventura

  175. High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors

    Article • International Journal of Molecular Sciences, March 2017, MDPI AG

    Salvador Ventura

  176. Copper(II) and the pathological H50Q α-synuclein mutant: Environment meets genetics

    Article • Communicative & Integrative Biology, January 2017, Taylor & Francis

    Salvador Ventura

  177. Amyloid cores in prion domains: Key regulators for prion conformational conversion

    Article • Prion, January 2017, Taylor & Francis

    Salvador Ventura

  178. Prediction of Protein Aggregation and Amyloid Formation

    Article • January 2017, Springer Science + Business Media

    Salvador Ventura

  179. DisProt 7.0: a major update of the database of disordered proteins

    Article • Nucleic Acids Research, December 2016, Oxford University Press (OUP)

    Salvador Ventura

  180. The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation

    Article • Acta Neuropathologica Communications, December 2016, Springer Science + Business Media

    Salvador Ventura

  181. DisProt 7.0: a major update of the database of disordered proteins

    Article • Nucleic Acids Research, November 2016, Oxford University Press (OUP)

    Dr Sandra Macedo-Ribeiro, Salvador Ventura

  182. Dissecting the contribution of Staphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure

    Article • Scientific Reports, October 2016, Springer Science + Business Media

    Salvador Ventura

  183. Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity

    Article • Proceedings of the National Academy of Sciences, October 2016, Proceedings of the National Academy of Sciences

    Salvador Ventura

  184. A fast and specific method to screen for intracellular amyloid inhibitors using bacterial model systems

    Article • European Journal of Medicinal Chemistry, October 2016, Elsevier

    Salvador Ventura

  185. Characterization of Amyloid Cores in Prion Domains

    Article • Scientific Reports, September 2016, Nature

    Dr Natalia Sanchez de Groot, Salvador Ventura

  186. Understanding and predicting protein misfolding and aggregation: Insights from proteomics

    Article • PROTEOMICS, September 2016, Wiley

    Salvador Ventura

  187. Editorial: Protein Solubility and Aggregation in Bacteria

    Article • Frontiers in Microbiology, July 2016, Frontiers

    Salvador Ventura

  188. Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals

    Article • PLoS Pathogens, June 2016, PLOS

    Salvador Ventura

  189. Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation

    Article • International Journal of Molecular Sciences, June 2016, MDPI AG

    Dr Natalia Sanchez de Groot, Salvador Ventura

  190. Data on correlation between Aβ42 structural aggregation propensity and toxicity in bacteria

    Article • Data in Brief, June 2016, Elsevier

    Salvador Ventura

  191. Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration

    Article • FEBS Letters, February 2016, Wiley

    Salvador Ventura

  192. Mammalian prion amyloid formation in bacteria

    Article • Prion, February 2016, Taylor & Francis

    Yraima Cordeiro, Salvador Ventura

  193. Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity

    Article • Nature Communications, February 2016, Springer Science + Business Media

    Salvador Ventura

  194. Erratum

    Article • Autophagy, February 2016, Taylor & Francis

    Dr Janos KristonVizi, Juan Segura-Aguilar, Professor Nektarios Tavernarakis, Dr Reinhard Dechant, Dr Vasilis J Promponas, Professor Marc Lecuit, Professor Paula I. Moreira, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Professor Jean-François Beaulieu, Shile Huang, Maria João Sousa, Professor Godefridus J Peters, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Professor Abdel Halim Harrath, Professor Günther Weindl, Dr Marc Etienne Poirot, Paula Ludovico, Salvador Ventura

  195. Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsis

    Article • PLoS Genetics, January 2016, PLOS

    Salvador Ventura

  196. Curing bacterial infections with protein aggregates

    Article • Molecular Microbiology, January 2016, Wiley

    Salvador Ventura

  197. The Rho Termination Factor of Clostridium botulinum Contains a Prion-Like Domain with a Highly Amyloidogenic Core

    Article • Frontiers in Microbiology, January 2016, Frontiers

    Salvador Ventura

  198. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Article • Autophagy, January 2016, Taylor & Francis

    Professor CIRO ISIDORO, Dr Akira Matsuura, Prof Hirokazu Arimoto, Professor Marc Diederich, Maria Vaccaro, Professor Abdel Halim Harrath, Professor Hyun Kyu Song, Dr Takeshi Noda, Dr Regina Menezes, Dr Janos KristonVizi, Cristina Muñoz-Pinedo, Professor Nektarios Tavernarakis, Juan Segura-Aguilar, Professor Marc Lecuit, Leonardo Travassos, Prof Robert Bryson-Richardson, Isabelle Dugail, PD Dipl.-Ing. Dr. techn. Werner J Kovacs, Dr Luca Galluzzi, Dr Reinhard Dechant, Dr. Sandra Moreno, Maurizio Molinari, Dr Vasilis J Promponas, Professor Günther Weindl, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Maria João Sousa, Dr Janna Morrison, Professor Mark Cragg, Executive Director, The Hormel Institute Robert Clarke, Dr Eleonora García Véscovi, Paula Ludovico, Professor Jean-François Beaulieu, Shile Huang, Professor George Perry, Professor Godefridus J Peters, Shuo-Chien Ling, Professor Jiwu Wei, Deepak Shukla, Dave Bridges, Salvador Ventura

  199. In vivo amyloid aggregation kinetics tracked by time-lapse confocal microscopy in real-time

    Article • Biotechnology Journal, January 2016, Wiley

    Salvador Ventura

  200. Protein Solubility and Aggregation in Bacteria

    Article • January 2016, Frontiers

    Salvador Ventura

  201. Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria

    Article • Microbial Cell Factories, November 2015, Springer Science + Business Media

    Yraima Cordeiro, Salvador Ventura

  202. Prion-like proteins in bacteria

    Article • Frontiers in Microbiology, October 2015, Frontiers

    Dr Natalia Sanchez de Groot, Salvador Ventura

  203. Protein Misfolding Diseases

    Article • Future Science OA, August 2015, Taylor & Francis

    Salvador Ventura

  204. Aggregation Propensity of Neuronal Receptors: Potential Implications in Neurodegenerative Disorders

    Article • Future Science OA, July 2015, Taylor & Francis

    Salvador Ventura

  205. Possible Roles of Amyloids in Malaria Pathophysiology

    Article • Future Science OA, July 2015, Taylor & Francis

    Salvador Ventura

  206. Intradomain Confinement of Disulfides in the Folding of Two Consecutive Modules of the LDL Receptor

    Article • PLOS One, July 2015, PLOS

    Salvador Ventura

  207. The prion-like RNA-processing protein HNRPDL forms inherently toxic amyloid-like inclusion bodies in bacteria

    Article • Microbial Cell Factories, July 2015, Springer Science + Business Media

    Salvador Ventura

  208. Influence of Cytoplasmatic Folding on Mitochondrial Import

    Article • Current Medicinal Chemistry, July 2015, Bentham Science Publishers

    Salvador Ventura

  209. Histone H1 Favors Folding and Parallel Fibrillar Aggregation of the 1–42 Amyloid-β Peptide

    Article • Langmuir, June 2015, American Chemical Society (ACS)

    Salvador Ventura

  210. PrionW: a server to identify proteins containing glutamine/asparagine rich prion-like domains and their amyloid cores

    Article • Nucleic Acids Research, May 2015, Oxford University Press (OUP)

    Salvador Ventura

  211. Amyloids or prions? That is the question

    Article • Prion, May 2015, Taylor & Francis

    Salvador Ventura

  212. AGGRESCAN3D (A3D): server for prediction of aggregation properties of protein structures

    Article • Nucleic Acids Research, April 2015, Oxford University Press (OUP)

    Salvador Ventura

  213. Structural and Computational Insights into Conformational Diseases: A Review

    Article • February 2015, Bentham Science Publishers

    Dr Natalia Sanchez de Groot, Salvador Ventura

  214. Proteome response at the edge of protein aggregation

    Article • Open Biology, February 2015, Royal Society Publishing

    Dr Natalia Sanchez de Groot, Salvador Ventura

  215. What Makes a Protein Sequence a Prion?

    Article • PLoS Computational Biology, January 2015, PLOS

    Salvador Ventura

  216. Protein Aggregation and Its Prediction

    Article • January 2015, Springer Science + Business Media

    Salvador Ventura

  217. Multifaceted Roles of Crystallography in Modern Drug Discovery

    Article • January 2015, Springer Science + Business Media

    Salvador Ventura

  218. Desoxipipradrol. Fármacos antiguos, problemas nuevos

    Article • Revista del Laboratorio Clínico, January 2015, Elsevier

    Salvador Ventura

  219. Characterization of Amyloid-Like Properties in Bacterial Intracellular Aggregates

    Article • November 2014, Springer Science + Business Media

    Salvador Ventura

  220. Amyloid Formation by Human Carboxypeptidase D Transthyretin-like Domain under Physiological Conditions

    Article • Journal of Biological Chemistry, October 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Julia Lorenzo, Salvador Ventura

  221. The Importance of a Gatekeeper Residue on the Aggregation of Transthyretin

    Article • Journal of Biological Chemistry, October 2014, Elsevier

    Salvador Ventura

  222. Fluorescent dye ProteoStat to detect and discriminate intracellular amyloid-like aggregates inEscherichia coli

    Article • Biotechnology Journal, September 2014, Wiley

    Salvador Ventura

  223. The small GTPase Rab11 co-localizes with  -synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity

    Article • Human Molecular Genetics, August 2014, Oxford University Press (OUP)

    Salvador Ventura

  224. Human Stefin B Role in Cell's Response to Misfolded Proteins and Autophagy

    Article • PLOS One, July 2014, PLOS

    Dr Uros Petrovic, Salvador Ventura

  225. Association Between Foldability and Aggregation Propensity in Small Disulfide-Rich Proteins

    Article • Antioxidants & Redox Signaling, July 2014, SAGE Publications

    Salvador Ventura

  226. Screening for Amyloid Aggregation: In-Silico, In-Vitro and In-Vivo Detection

    Article • Current Protein and Peptide Science, May 2014, Bentham Science Publishers

    Salvador Ventura

  227. Selection against toxic aggregation-prone protein sequences in bacteria

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, May 2014, Elsevier

    Salvador Ventura

  228. Inclusion Bodies in the Study of Amyloid Aggregation

    Article • April 2014, Wiley

    Salvador Ventura

  229. The Mitochondrial Intermembrane Space Oxireductase Mia40 Funnels the Oxidative Folding Pathway of the Cytochrome c Oxidase Assembly Protein Cox19

    Article • Journal of Biological Chemistry, April 2014, Elsevier

    Salvador Ventura

  230. N-Terminal Protein Tails Act as Aggregation Protective Entropic Bristles: The SUMO Case

    Article • Biomacromolecules, March 2014, American Chemical Society (ACS)

    Salvador Ventura

  231. Thioflavin-S Staining of Bacterial Inclusion Bodies for the Fast, Simple, and Inexpensive Screening of Amyloid Aggregation Inhibitors

    Article • Current Medicinal Chemistry, February 2014, Bentham Science Publishers

    Salvador Ventura

  232. PrionScan: an online database of predicted prion domains in complete proteomes

    Article • BMC Genomics, January 2014, Springer Science + Business Media

    Salvador Ventura

  233. Correction: Structure-Based Analysis of A19D, a Variant of Transthyretin Involved in Familial Amyloid Cardiomyopathy

    Article • PLOS One, December 2013, PLOS

    Salvador Ventura

  234. Structure-Based Analysis of A19D, a Variant of Transthyretin Involved in Familial Amyloid Cardiomyopathy

    Article • PLOS One, December 2013, PLOS

    Salvador Ventura

  235. Protein aggregation propensity is a crucial determinant of intracellular inclusion formation and quality control degradation

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 2013, Elsevier

    Salvador Ventura

  236. About targets and causes in protein folding

    Article • Journal of Biomolecular Structure and Dynamics, September 2013, Taylor & Francis

    Salvador Ventura

  237. Trifluoroethanol Modulates Amyloid Formation by the All α-Helical URN1 FF Domain

    Article • International Journal of Molecular Sciences, August 2013, MDPI AG

    Salvador Ventura

  238. Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains

    Article • BMC Genomics, May 2013, Springer Science + Business Media

    Salvador Ventura

  239. The N-terminal Helix Controls the Transition between the Soluble and Amyloid States of an FF Domain

    Article • PLOS One, March 2013, PLOS

    Salvador Ventura

  240. Inhibition of Human Transthyretin Aggregation by Non-Steroidal Anti-Inflammatory Compounds: A Structural and Thermodynamic Analysis

    Article • International Journal of Molecular Sciences, March 2013, MDPI AG

    Salvador Ventura

  241. Oxidative Folding in the Mitochondrial Intermembrane Space in Human Health and Disease

    Article • International Journal of Molecular Sciences, January 2013, MDPI AG

    Salvador Ventura

  242. Thioflavin-T excimer formation upon interaction with amyloid fibers

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Salvador Ventura

  243. Amyloid Formation in Bacteria

    Article • January 2013, Springer Science + Business Media

    Salvador Ventura

  244. Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, January 2013, Elsevier

    Salvador Ventura

  245. Discovery of Novel Inhibitors of Amyloid β-Peptide 1–42 Aggregation

    Article • Journal of Medicinal Chemistry, October 2012, American Chemical Society (ACS)

    Salvador Ventura

  246. Evolutionary selection for protein aggregation

    Article • Biochemical Society Transactions, October 2012, Portland Press Ltd.

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas, Salvador Ventura

  247. Protein aggregation: Mechanisms and functional consequences

    Article • The International Journal of Biochemistry & Cell Biology, September 2012, Elsevier

    Salvador Ventura

  248. The Effect of Amyloidogenic Peptides on Bacterial Aging Correlates with Their Intrinsic Aggregation Propensity

    Article • Journal of Molecular Biology, August 2012, Elsevier

    Dr Natalia Sanchez de Groot, Salvador Ventura

  249. Effect of the surface charge of artificial model membranes on the aggregation of amyloid β-peptide

    Article • Biochimie, August 2012, Elsevier

    Salvador Ventura

  250. Yeast prions form infectious amyloid inclusion bodies in bacteria

    Article • Microbial Cell Factories, June 2012, Springer Science + Business Media

    Salvador Ventura

  251. Native Structure Protects SUMO Proteins from Aggregation into Amyloid Fibrils

    Article • Biomacromolecules, May 2012, American Chemical Society (ACS)

    Salvador Ventura

  252. Protein Oxidative Folding in the Intermembrane Mitochondrial Space: More than Protein Trafficking

    Article • Current Protein and Peptide Science, May 2012, Bentham Science Publishers

    Salvador Ventura

  253. Thioflavin-S staining coupled to flow cytometry. A screening tool to detect in vivo protein aggregation

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Salvador Ventura

  254. Self-assembly of human amylin-derived peptides studied by atomic force microscopy and single molecule force spectroscopy

    Article • Soft Matter, January 2012, Royal Society of Chemistry

    Salvador Ventura

  255. Using bacterial inclusion bodies to screen for amyloid aggregation inhibitors

    Article • Microbial Cell Factories, January 2012, Springer Science + Business Media

    Dr Natalia Sanchez de Groot, Salvador Ventura

  256. Contribution of Disulfide Bonds to Stability, Folding, and Amyloid Fibril Formation: The PI3-SH3 Domain Case

    Article • Antioxidants & Redox Signaling, January 2012, Mary Ann Liebert Inc

    Dr Natalia Sanchez de Groot, Salvador Ventura

  257. Protein aggregation profile of the human kinome

    Article • Frontiers in Physiology, January 2012, Frontiers

    Salvador Ventura

  258. Protein Aggregation Acts as Strong Constraint During Evolution

    Article • January 2012, Springer Science + Business Media

    Salvador Ventura

  259. Cross-β-Sheet Supersecondary Structure in Amyloid Folds: Techniques for Detection and Characterization

    Article • January 2012, Springer Science + Business Media

    Salvador Ventura

  260. Modeling amyloids in bacteria

    Article • Microbial Cell Factories, January 2012, Springer Science + Business Media

    Salvador Ventura

  261. Multiple β‐sheet molecular dynamics of amyloid formation from two ABl‐SH3 domain peptides

    Article • Biopolymers, January 2012, Wiley

    Salvador Ventura

  262. Temperature Dependence of the Aggregation Kinetics of Sup35 and Ure2p Yeast Prions

    Article • Biomacromolecules, December 2011, American Chemical Society (ACS)

    Salvador Ventura

  263. AGGRESCAN: Method, Application, and Perspectives for Drug Design

    Article • November 2011, Springer Science + Business Media

    Dr Natalia Sanchez de Groot, Salvador Ventura

  264. Bimolecular Fluorescence Complementation: Illuminating Cellular Protein Interactions

    Article • Current Molecular Medicine, October 2011, Bentham Science Publishers

    Salvador Ventura

  265. Biological role of bacterial inclusion bodies: a model for amyloid aggregation

    Article • FEBS Journal, May 2011, Wiley

    Dr Natalia Sanchez de Groot, Salvador Ventura

  266. Prediction of the aggregation propensity of proteins from the primary sequence: Aggregation properties of proteomes

    Article • Biotechnology Journal, April 2011, Wiley

    Salvador Ventura

  267. The aggregation properties of Escherichia coli proteins associated with their cellular abundance

    Article • Biotechnology Journal, April 2011, Wiley

    Salvador Ventura

  268. Aggregation of the neuroblastoma-associated mutant (S120G) of the human nucleoside diphosphate kinase-A/NM23-H1 into amyloid fibrils

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, April 2011, Springer Science + Business Media

    Salvador Ventura

  269. Does Stoichiometry Drive Protein Folding?

    Article • Journal of Biomolecular Structure and Dynamics, February 2011, Taylor & Francis

    Salvador Ventura

  270. Bacterial Inclusion Bodies of Alzheimer's Disease β‐Amyloid Peptides Can Be Employed To Study Native‐Like Aggregation Intermediate States

    Article • ChemBioChem, January 2011, Wiley

    Salvador Ventura

  271. Linking amyloid protein aggregation and yeast survival

    Article • Molecular BioSystems, January 2011, Royal Society of Chemistry

    Dr Natalia Sanchez de Groot, Salvador Ventura

  272. Folding of Disulfide Proteins

    Article • January 2011, Springer Science + Business Media

    Salvador Ventura

  273. Oxidative Folding: Coupling Conformational Folding and Disulfide Formation

    Article • January 2011, Springer Science + Business Media

    Salvador Ventura

  274. Protease Inhibitors as Models for the Study of Oxidative Folding

    Article • Antioxidants & Redox Signaling, January 2011, SAGE Publications

    Salvador Ventura

  275. Deciphering the role of the thermodynamic and kinetic stabilities of SH3 domains on their aggregation inside bacteria

    Article • PROTEOMICS, November 2010, Wiley

    Salvador Ventura

  276. The Role of Protein Sequence and Amino Acid Composition in Amyloid Formation: Scrambling and Backward Reading of IAPP Amyloid Fibrils

    Article • Journal of Molecular Biology, November 2010, Elsevier

    Dr Natalia Sanchez de Groot, Salvador Ventura

  277. Modulation of Aβ42 fibrillogenesis by glycosaminoglycan structure

    Article • The FASEB Journal, November 2010, Federation of American Societies For Experimental Biology (FASEB)

    Dr Natalia Sanchez de Groot, Salvador Ventura

  278. Amyloid-Like Protein Inclusions in Tobacco Transgenic Plants

    Article • PLOS One, October 2010, PLOS

    Salvador Ventura

  279. Protein folding and aggregation in bacteria

    Article • Cellular and Molecular Life Sciences, April 2010, Springer Science + Business Media

    Dr Natalia Sanchez de Groot, Salvador Ventura

  280. Protein Aggregation Profile of the Bacterial Cytosol

    Article • PLOS One, February 2010, PLOS

    Dr Natalia Sanchez de Groot, Salvador Ventura

  281. Deciphering the Structural Basis That Guides the Oxidative Folding of Leech-derived Tryptase Inhibitor

    Article • Journal of Biological Chemistry, December 2009, Elsevier

    Salvador Ventura

  282. Designing Out Disulfide Bonds of Leech Carboxypeptidase Inhibitor: Implications for Its Folding, Stability and Function

    Article • Journal of Molecular Biology, September 2009, Elsevier

    Salvador Ventura

  283. Amyloids in bacterial inclusion bodies

    Article • New Biotechnology, September 2009, Elsevier

    Salvador Ventura

  284. Energy barriers for HET‐s prion forming domain amyloid formation

    Article • FEBS Journal, August 2009, Wiley

    Salvador Ventura

  285. Amyloidogenic Regions and Interaction Surfaces Overlap in Globular Proteins Related to Conformational Diseases

    Article • PLoS Computational Biology, August 2009, PLOS

    Salvador Ventura

  286. Amyloids in bacterial inclusion bodies

    Article • Trends in Biochemical Sciences, August 2009, Elsevier

    Dr Natalia Sanchez de Groot, Salvador Ventura

  287. Protein complementation assays: Approaches for the in vivo analysis of protein interactions

    Article • FEBS Letters, March 2009, Wiley

    Salvador Ventura

  288. Design, Selection, and Characterization of Thioflavin-Based Intercalation Compounds with Metal Chelating Properties for Application in Alzheimer’s Disease

    Article • Journal of the American Chemical Society, February 2009, American Chemical Society (ACS)

    Dr Natalia Sanchez de Groot, Salvador Ventura

  289. Detecting and Interfering Protein Interactions: Towards the Control of Biochemical Pathways

    Article • Current Medicinal Chemistry, January 2009, Bentham Science Publishers

    Salvador Ventura

  290. Characterization of the amyloid bacterial inclusion bodies of the HET-s fungal prion

    Article • Microbial Cell Factories, January 2009, Springer Science + Business Media

    Salvador Ventura

  291. Dynamics study on single and multiple β-sheets

    Article • January 2009, Springer Science + Business Media

    Salvador Ventura

  292. Sulfated Polysaccharides Promote the Assembly of Amyloid β1–42 Peptide into Stable Fibrils of Reduced Cytotoxicity

    Article • Journal of Biological Chemistry, November 2008, Elsevier

    Salvador Ventura

  293. Kinetic and thermodynamic stability of bacterial intracellular aggregates

    Article • FEBS Letters, October 2008, Wiley

    Salvador Ventura

  294. The NMR Structures of the Major Intermediates of the Two-domain Tick Carboxypeptidase Inhibitor Reveal Symmetry in Its Folding and Unfolding Pathways

    Article • Journal of Biological Chemistry, October 2008, Elsevier

    Salvador Ventura

  295. Inclusion bodies: Specificity in their aggregation process and amyloid-like structure

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 2008, Elsevier

    Salvador Ventura

  296. Monitoring the interference of protein‐protein interactions in vivo by bimolecular fluorescence complementation: the DnaK case

    Article • PROTEOMICS, August 2008, Wiley

    Salvador Ventura

  297. Studies on bacterial inclusion bodies

    Article • Future Microbiology, August 2008, Future Medicine

    Dr Natalia Sanchez de Groot, Salvador Ventura

  298. Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid)

    Article • Acta Crystallographica Section D Biological Crystallography, June 2008, International Union of Crystallography

    Salvador Ventura

  299. Recent Structural and Computational Insights into Conformational Diseases

    Article • Current Medicinal Chemistry, June 2008, Bentham Science Publishers

    Dr Natalia Sanchez de Groot, Salvador Ventura

  300. The in Vivo and in Vitro Aggregation Properties of Globular Proteins Correlate With Their Conformational Stability: The SH3 Case

    Article • Journal of Molecular Biology, May 2008, Elsevier

    Dr Natalia Sanchez de Groot, Salvador Ventura

  301. Scrambled Isomers as Key Intermediates in the Oxidative Folding of Ligand Binding Module 5 of the Low Density Lipoprotein Receptor

    Article • Journal of Biological Chemistry, May 2008, Elsevier

    Salvador Ventura

  302. Oxidative Protein Folding: From the Test Tube to In Vivo Insights

    Article • Antioxidants & Redox Signaling, January 2008, SAGE Publications

    Salvador Ventura

  303. Oxidative Folding of Leech-Derived Tryptase Inhibitor Via Native Disulfide-Bonded Intermediates

    Article • Antioxidants & Redox Signaling, January 2008, SAGE Publications

    Salvador Ventura

  304. Study and selection of in vivo protein interactions by coupling bimolecular fluorescence complementation and flow cytometry

    Article • Nature Protocols, December 2007, Springer Science + Business Media

    Salvador Ventura

  305. Self-assembly of human latexin into amyloid-like oligomers

    Article • BMC Structural Biology, November 2007, Springer Science + Business Media

    Salvador Ventura

  306. Prion and Non-prion Amyloids of the HET-s Prion forming Domain

    Article • Journal of Molecular Biology, July 2007, Elsevier

    Dr Natalia Sanchez de Groot, Salvador Ventura

  307. Detection of transient protein–protein interactions by bimolecular fluorescence complementation: The Abl‐SH3 case

    Article • PROTEOMICS, March 2007, Wiley

    Salvador Ventura

  308. Ile-Phe Dipeptide Self-Assembly: Clues to Amyloid Formation

    Article • Biophysical Journal, March 2007, Elsevier

    Dr Natalia Sanchez de Groot, Salvador Ventura

  309. AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides

    Article • BMC Bioinformatics, January 2007, Springer Science + Business Media

    Dr Natalia Sanchez de Groot, Salvador Ventura

  310. Molecular dynamics study of amyloid formation of two Abl‐SH3 domain peptides

    Article • Journal of Peptide Science, November 2006, Wiley

    Salvador Ventura

  311. Effect of temperature on protein quality in bacterial inclusion bodies

    Article • FEBS Letters, November 2006, Wiley

    Dr Natalia Sanchez de Groot, Salvador Ventura

  312. Protein aggregation into bacterial inclusion bodies is a specific kinetically driven process

    Article • Microbial Cell Factories, October 2006, Springer Science + Business Media

    Dr Natalia Sanchez de Groot, Salvador Ventura

  313. Design and NMR conformational study of a β‐sheet peptide based on Betanova and WW domains

    Article • Protein Science, October 2006, Wiley

    Salvador Ventura

  314. The chaperone DnaK controls the fractioning of functional protein between soluble and insoluble cell fractions in inclusion body-forming cells

    Article • Microbial Cell Factories, August 2006, Springer Science + Business Media

    Salvador Ventura

  315. Protein activity in bacterial inclusion bodies correlates with predicted aggregation rates

    Article • Journal of Biotechnology, August 2006, Elsevier

    Dr Natalia Sanchez de Groot, Salvador Ventura

  316. Characterizing the Tick Carboxypeptidase Inhibitor

    Article • Journal of Biological Chemistry, June 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Juan Calvete, Salvador Ventura

  317. Folding of small disulfide-rich proteins: clarifying the puzzle

    Article • Trends in Biochemical Sciences, May 2006, Elsevier

    Salvador Ventura

  318. Protein quality in bacterial inclusion bodies

    Article • Trends in Biotechnology, April 2006, Elsevier

    Salvador Ventura

  319. Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities

    Article • FEBS Journal, February 2006, Wiley

    Dr Natalia Sanchez de Groot, Salvador Ventura

  320. Aggregation as bacterial inclusion bodies does not imply inactivation of enzymes and fluorescent proteins

    Article • Microbial Cell Factories, September 2005, Springer Science + Business Media

    Salvador Ventura

  321. Study of a Major Intermediate in the Oxidative Folding of Leech Carboxypeptidase Inhibitor: Contribution of the Fourth Disulfide Bond

    Article • Journal of Molecular Biology, September 2005, Elsevier

    Salvador Ventura

  322. Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin

    Article • Cellular and Molecular Life Sciences, August 2005, Springer Science + Business Media

    Salvador Ventura

  323. NMR Structural Characterization and Computational Predictions of the Major Intermediate in Oxidative Folding of Leech Carboxypeptidase Inhibitor

    Article • Structure, August 2005, Elsevier

    Salvador Ventura

  324. Sequence determinants of protein aggregation: tools to increase protein solubility

    Article • Microbial Cell Factories, April 2005, Springer Science + Business Media

    Salvador Ventura

  325. Amyloid-like Properties of Bacterial Inclusion Bodies

    Article • Journal of Molecular Biology, April 2005, Elsevier

    Salvador Ventura

  326. Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin

    Article • Proceedings of the National Academy of Sciences, February 2005, Proceedings of the National Academy of Sciences

    Salvador Ventura

  327. Prediction of "hot spots" of aggregation in disease-linked polypeptides

    Article • BMC Structural Biology, January 2005, Springer Science + Business Media

    Dr Natalia Sanchez de Groot, Salvador Ventura

  328. Amyloid fibril formation by bovine cytochromec

    Article • Spectroscopy An International Journal, January 2005, Hindawi Publishing Corporation

    Dr Natalia Sanchez de Groot, Salvador Ventura

  329. Amyloid Fibril Formation by a Partially Structured Intermediate State of α-Chymotrypsin

    Article • Journal of Molecular Biology, September 2004, Elsevier

    Salvador Ventura

  330. Role of Kinetic Intermediates in the Folding of Leech Carboxypeptidase Inhibitor

    Article • Journal of Biological Chemistry, June 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Julia Lorenzo, Salvador Ventura

  331. Secondary Binding Site of the Potato Carboxypeptidase Inhibitor. Contribution to Its Structure, Folding, and Biological Properties†

    Article • Biochemistry, June 2004, American Chemical Society (ACS)

    PhD Julia Lorenzo, Salvador Ventura

  332. Designing proteins from the inside out

    Article • Proteins Structure Function and Bioinformatics, May 2004, Wiley

    Salvador Ventura

  333. Short amino acid stretches can mediate amyloid formation in globular proteins: The Src homology 3 (SH3) case

    Article • Proceedings of the National Academy of Sciences, May 2004, Proceedings of the National Academy of Sciences

    Salvador Ventura

  334. Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation

    Article • Biological Chemistry, January 2004, De Gruyter

    Salvador Ventura

  335. Folding specificity induced by loop stiffness

    Article • Protein Science, July 2003, Wiley

    Salvador Ventura

  336. Structure and dynamics of the potato carboxypeptidase inhibitor by 1H and 15N NMR

    Article • Proteins Structure Function and Bioinformatics, January 2003, Wiley

    Salvador Ventura

  337. Spectroscopic Analysis of Amyloid Fibril Formation in SH3‐Domains

    Article • Journal of Spectroscopy, January 2003, Wiley

    Salvador Ventura

  338. Insights into the Origin of the Tendency of the PI3-SH3 Domain to form Amyloid Fibrils

    Article • Journal of Molecular Biology, October 2002, Elsevier

    Salvador Ventura

  339. Conformational strain in the hydrophobic core and its implications for protein folding and design

    Article • Nature Structural Biology, May 2002, Springer Science + Business Media

    Salvador Ventura

  340. Mapping the Pro-region of Carboxypeptidase B by Protein Engineering

    Article • Journal of Biological Chemistry, July 1999, Elsevier

    Salvador Ventura

  341. Overexpression of Human Procarboxypeptidase A2 in Pichia pastoris and Detailed Characterization of Its Activation Pathway

    Article • Journal of Biological Chemistry, February 1998, Elsevier

    Salvador Ventura

  342. Cutting at the right place

    Article • FEBS Journal, February 1998, Wiley

    Salvador Ventura

  343. Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation 1 1Edited by I. A. Wilson

    Article • Journal of Molecular Biology, July 1997, Elsevier

    Salvador Ventura

  344. Crystallization and preliminary X‐ray analysis of the ternary complex of procarboxypeptidase A from bovine pancreas

    Article • FEBS Letters, July 1995, Wiley

    Salvador Ventura

  345. Procarboxypeptidase in rat pancreas Overall characterization and comparison of the activation processes

    Article • FEBS Journal, May 1994, Wiley

    Salvador Ventura