All Stories

  1. (Dys)functional insights into nucleic acids and RNA-binding proteins modulation of the prion protein and α-synuclein phase separation

    Article • Biophysical Reviews, June 2023, Springer Science + Business Media

    Yraima Cordeiro

  2. Copper drives prion protein phase separation and modulates aggregation

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Yraima Cordeiro

  3. Nucleic acid actions on abnormal protein aggregation, phase transitions and phase separation

    Article • Current Opinion in Structural Biology, April 2022, Elsevier

    Yraima Cordeiro

  4. Phase separation of the mammalian prion protein: Physiological and pathological perspectives

    Article • Journal of Neurochemistry, March 2022, Wiley

    Yraima Cordeiro

  5. Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo

    Article • Molecular Therapy, September 2021, Elsevier

    Yraima Cordeiro

  6. Green Tea Epigallocatechin-3-gallate (EGCG) Targeting Protein Misfolding in Drug Discovery for Neurodegenerative Diseases

    Article • Biomolecules, May 2021, MDPI AG

    Yraima Cordeiro

  7. RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction

    Article • Scientific Reports, August 2019, Springer Science + Business Media

    Yraima Cordeiro

  8. Design, synthesis, structural characterization and in vitro evaluation of new 1,4-disubstituted-1,2,3-triazole derivatives against glioblastoma cells

    Article • Bioorganic Chemistry, March 2019, Elsevier

    Yraima Cordeiro

  9. Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2019, Taylor & Francis

    Yraima Cordeiro, Arthur Kümmerle, Carlos Sant Anna

  10. A Promising Antiprion Trimethoxychalcone Binds to the Globular Domain of the Cellular Prion Protein and Changes Its Cellular Location

    Article • Antimicrobial Agents and Chemotherapy, November 2017, ASM Journals

    Yraima Cordeiro

  11. Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids

    Article • International Journal of Molecular Sciences, May 2017, MDPI AG

    Yraima Cordeiro

  12. Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain

    Article • Journal of Biological Chemistry, April 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Yraima Cordeiro

  13. Structural Basis for the Dissociation of Alpha-Synuclein Fibrils Triggered by Pressure Perturbation of the Hydrophobic Core

    Article • Biophysical Journal, February 2017, Elsevier

    Yraima Cordeiro

  14. Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core

    Article • Scientific Reports, November 2016, Nature

    Yraima Cordeiro

  15. Virtual drug screening for prion diseases: A valuable step?

    Article • EBioMedicine, July 2016, Elsevier

    Yraima Cordeiro

  16. Mammalian prion amyloid formation in bacteria

    Article • Prion, February 2016, Taylor & Francis

    Yraima Cordeiro

  17. Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria

    Article • Microbial Cell Factories, November 2015, Springer Science + Business Media

    Yraima Cordeiro

  18. Biophysical Studies on BEX3, the p75NTR-Associated Cell Death Executor, Reveal a High-Order Oligomer with Partially Folded Regions

    Article • PLoS ONE, September 2015, PLOS

    Yraima Cordeiro

  19. Hot Topics in Biomedical Sciences

    Article • Anais da Academia Brasileira de Ciências, August 2015, FapUNIFESP (SciELO)

    Yraima Cordeiro

  20. New Approaches for the Selection and Evaluation of Anti-Prion Organic Compounds

    Article • Mini-Reviews in Medicinal Chemistry, March 2015, Bentham Science Publishers

    Yraima Cordeiro

  21. Pathological implications of nucleic acid interactions with proteins associated with neurodegenerative diseases

    Article • Biophysical Reviews, January 2014, Springer Science + Business Media

    Yraima Cordeiro

  22. Conformational dissection of Thermomyces lanuginosus lipase in solution

    Article • Biophysical Chemistry, January 2014, Elsevier

    Yraima Cordeiro

  23. The effect of temperature on protein refolding at high pressure: Enhanced green fluorescent protein as a model

    Article • Process Biochemistry, January 2014, Elsevier

    Yraima Cordeiro

  24. Pressure–temperature folding landscape in proteins involved in neurodegenerative diseases and cancer

    Article • Biophysical Chemistry, December 2013, Elsevier

    Yraima Cordeiro

  25. Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor

    Article • Bioscience Reports, July 2013, Portland Press Ltd.

    Yraima Cordeiro

  26. A Comprehensive Study on the Activity and Deactivation of Immobilized Lecitase Ultra in Esterifications of Food Waste Streams to Monoacylglycerols

    Article • ChemSusChem, March 2013, Wiley

    Rafael Luque Alvarez de Sotomayor, Professor Rodrigo Octavio Mendonça Alves de Souza, Yraima Cordeiro

  27. An analysis of the factors that affect the dissociation of inclusion bodies and the refolding of endostatin under high pressure

    Article • Process Biochemistry, February 2013, Elsevier

    Yraima Cordeiro

  28. Insights into the Intramolecular Coupling between the N- and C-Domains of Troponin C Derived from High-Pressure, Fluorescence, Nuclear Magnetic Resonance, and Small-Angle X-ray Scattering Studies

    Article • Biochemistry, January 2013, American Chemical Society (ACS)

    Yraima Cordeiro

  29. Continuous flow valorization of fatty acid waste using silica-immobilized lipases

    Article • Green Chemistry, January 2013, Royal Society of Chemistry

    Rafael Luque Alvarez de Sotomayor, Yraima Cordeiro

  30. Moniliophthora perniciosa Necrosis- and Ethylene-Inducing Protein 2 (MpNep2) as a Metastable Dimer in Solution: Structural and Functional Implications

    Article • PLoS ONE, September 2012, PLOS

    Professor Ana Paula Valente, Yraima Cordeiro

  31. Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils

    Article • Journal of Biological Chemistry, August 2012, Elsevier

    Yraima Cordeiro

  32. Nonspecific Prion Protein–Nucleic Acid Interactions Lead to Different Aggregates and Cytotoxic Species

    Article • Biochemistry, July 2012, American Chemical Society (ACS)

    Yraima Cordeiro

  33. The role of RNA in mammalian prion protein conversion

    Article • Wiley Interdisciplinary Reviews - RNA, November 2011, Wiley

    Yraima Cordeiro

  34. Allosteric function and dysfunction of the prion protein

    Article • Cellular and Molecular Life Sciences, October 2011, Springer Science + Business Media

    Yraima Cordeiro

  35. Erratum to “Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors” [Int. J. Biochem. Cell Biol. 43 (1) (2011) 60–64]

    Article • The International Journal of Biochemistry & Cell Biology, June 2011, Elsevier

    Yraima Cordeiro

  36. Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion

    Article • Methods, March 2011, Elsevier

    Yraima Cordeiro

  37. Heparin Binding by Murine Recombinant Prion Protein Leads to Transient Aggregation and Formation of RNA-Resistant Species

    Article • Journal of the American Chemical Society, January 2011, American Chemical Society (ACS)

    Yraima Cordeiro

  38. Hydrophilic cyclodextrin protected Pd nanoclusters: insights into their size control and host–guest behavior

    Article • Journal of Materials Chemistry, January 2011, Royal Society of Chemistry

    Yraima Cordeiro

  39. Synthesis and anti-prion activity evaluation of aminoquinoline analogues

    Article • European Journal of Medicinal Chemistry, November 2010, Elsevier

    Yraima Cordeiro

  40. Subunit–subunit interactions and overall topology of the dimeric mitochondrial ATP synthase of Polytomella sp.

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, August 2010, Elsevier

    Yraima Cordeiro

  41. 3D-reconstruction and overall topology of the dimeric mitochondrial ATP synthase of the colorless alga Polytomella sp

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, July 2010, Elsevier

    Yraima Cordeiro

  42. Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins†

    Article • Accounts of Chemical Research, February 2010, American Chemical Society (ACS)

    Yraima Cordeiro

  43. PrP interactions with nucleic acids and glycosaminoglycans in function and disease

    Article • Frontiers in Bioscience, January 2010, IMR Press

    Yraima Cordeiro

  44. The p53 Core Domain Is a Molten Globule at Low pH

    Article • Journal of Biological Chemistry, November 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Ana Paula Valente, Yraima Cordeiro

  45. Effects of compressed fluids on the activity and structure of horseradish peroxidase

    Article • The Journal of Supercritical Fluids, September 2009, Elsevier

    Yraima Cordeiro

  46. Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STIl

    Article • The FASEB Journal, August 2009, Wiley

    Yraima Cordeiro

  47. Cognate DNA Stabilizes the Tumor Suppressor p53 and Prevents Misfolding and Aggregation

    Article • Biochemistry, July 2009, American Chemical Society (ACS)

    Yraima Cordeiro

  48. Enhanced prion protein stability coupled to DNA recognition and milieu acidification

    Article • Biophysical Chemistry, May 2009, Elsevier

    Yraima Cordeiro

  49. Response to Radulescu and Brenig: Infectious nucleic acids in prion disease: halfway there

    Article • Trends in Biochemical Sciences, January 2009, Elsevier

    Yraima Cordeiro

  50. Prion Protein Complexed to N2a Cellular RNAs through Its N-terminal Domain Forms Aggregates and Is Toxic to Murine Neuroblastoma Cells

    Article • Journal of Biological Chemistry, July 2008, Elsevier

    Yraima Cordeiro

  51. Recognition mechanism of d- and l-tryptophan enantiomers using 2-hydroxypropyl-α- or β-cyclodextrins as chiral selectors

    Article • Tetrahedron Asymmetry, May 2008, Elsevier

    Yraima Cordeiro

  52. The peculiar interaction between mammalian prion protein and RNA

    Article • Prion, April 2008, Taylor & Francis

    Yraima Cordeiro

  53. Intriguing nucleic-acid-binding features of mammalian prion protein

    Article • Trends in Biochemical Sciences, March 2008, Elsevier

    Yraima Cordeiro

  54. Fourier Transform Infrared Spectroscopy Provides a Fingerprint for the Tetramer and for the Aggregates of Transthyretin

    Article • Biophysical Journal, August 2006, Elsevier

    Yraima Cordeiro

  55. Structural Insights into the Interaction between Prion Protein and Nucleic Acid†

    Article • Biochemistry, August 2006, American Chemical Society (ACS)

    Yraima Cordeiro

  56. Microbial reduction of α-acetyl-γ-butyrolactone

    Article • Tetrahedron Asymmetry, March 2006, Elsevier

    Dr Carlos AM Fraga, Yraima Cordeiro, Professor Francisco Radler de Aquino Neto

  57. Protein folding and aggregation: Two sides of the same coin in the condensation of proteins revealed by pressure studies

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, March 2006, Elsevier

    Yraima Cordeiro

  58. The Amino-Terminal PrP Domain Is Crucial to Modulate Prion Misfolding and Aggregation

    Article • Biophysical Journal, October 2005, Elsevier

    Yraima Cordeiro

  59. Volume and energy folding landscape of prion protein revealed by pressure

    Article • Brazilian Journal of Medical and Biological Research, August 2005, FapUNIFESP (SciELO)

    Yraima Cordeiro

  60. The Hypothesis of the Catalytic Action of Nucleic Acid on the Conversion of Prion Protein

    Article • Protein and Peptide Letters, April 2005, Bentham Science Publishers

    Yraima Cordeiro

  61. Hydration and Packing Effects on Prion Folding and β-Sheet Conversion

    Article • Journal of Biological Chemistry, July 2004, Elsevier

    Yraima Cordeiro

  62. Modulation of Prion Protein Oligomerization, Aggregation, and β-sheet Conversion by 4,4′-Dianilino-1,1′-binaphthyl-5,5′-sulfonate (bis-ANS)

    Article • Journal of Biological Chemistry, February 2004, Elsevier

    Yraima Cordeiro

  63. Fibrillar Aggregates of the Tumor Suppressor p53 Core Domain†

    Article • Biochemistry, August 2003, American Chemical Society (ACS)

    Yraima Cordeiro

  64. DNA Converts Cellular Prion Protein into the β-Sheet Conformation and Inhibits Prion Peptide Aggregation

    Article • Journal of Biological Chemistry, December 2001, Elsevier

    Yraima Cordeiro

  65. Pressure-induced formation of inactive triple-shelled rotavirus particles is associated with changes in the spike protein VP4

    Article • Journal of Molecular Biology, April 2001, Elsevier

    Yraima Cordeiro