All Stories

  1. Time-resolved dual transcriptomics of Pseudomonas aeruginosa biofilm formation in cystic fibrosis

    Article • Biofilm, December 2025, Elsevier

    Dr Marc Torrent Burgas

  2. Evaluating ligand docking methods for drugging protein–protein interfaces: insights from AlphaFold2 and molecular dynamics refinement

    Article • Journal of Cheminformatics, September 2025, Springer Science + Business Media

    Dr Marc Torrent Burgas

  3. Exploring the therapeutic potential of recombinant bovine β-defensins for antimicrobial and anti-inflammatory functions in sepsis management

    Article • Veterinary Research, September 2025, Springer Science + Business Media

    Dr Marc Torrent Burgas

  4. Mining the heparinome for cryptic antimicrobial peptides that selectively kill Gram-negative bacteria

    Article • Molecular Systems Biology, May 2025, Springer Science + Business Media

    Dr Marc Torrent Burgas

  5. Targeting MarA N‐terminal domain dynamics to prevent DNA binding

    Article • Protein Science, December 2024, Wiley

    Dr Marc Torrent Burgas, Shina Caroline Lynn Kamerlin

  6. The limits of prediction: Why intrinsically disordered regions challenge our understanding of antimicrobial peptides

    Article • Computational and Structural Biotechnology Journal, December 2024, Elsevier

    Dr Marc Torrent Burgas

  7. The battle within: how Pseudomonas aeruginosa uses host-pathogen interactions to infect the human lung

    Article • Critical Reviews in Microbiology, October 2024, Taylor & Francis

    Dr Marc Torrent Burgas

  8. From In Vitro Promise to In Vivo Reality: An Instructive Account of Infection Model Evaluation of Antimicrobial Peptides

    Article • International Journal of Molecular Sciences, September 2024, MDPI AG

    Dr Marc Torrent Burgas

  9. From In Vitro Promise to In Vivo Reality: An Instructive Account of Infection Model Evaluation of Antimicrobial Peptides

    Article • August 2024, MDPI AG

    Dr Marc Torrent Burgas

  10. PyAMPA: a high-throughput prediction and optimization tool for antimicrobial peptides

    Article • mSystems, July 2024, ASM Journals

    Dr Marc Torrent Burgas

  11. The N-terminal helix of MarA as a key element in the mechanism of DNA binding

    Article • February 2024, Cold Spring Harbor Laboratory Press

    Dr Marc Torrent Burgas, Shina Caroline Lynn Kamerlin

  12. Structural assembly of the bacterial essential interactome

    Article • eLife, January 2024, eLife

    Dr Marc Torrent Burgas

  13. The C-Terminus of Panusin, a Lobster β-Defensin, Is Crucial for Optimal Antimicrobial Activity and Serum Stability

    Article • Pharmaceutics, June 2023, MDPI AG

    Dr Marc Torrent Burgas

  14. The PRALINE database: protein and Rna humAn singLe nucleotIde variaNts in condEnsates

    Article • Bioinformatics, January 2023, Oxford University Press (OUP)

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  15. Antimicrobial Peptides Can Generate Tolerance by Lag and Interfere with Antimicrobial Therapy

    Article • Pharmaceutics, October 2022, MDPI AG

    Dr Marc Torrent Burgas

  16. Analysis of Host–Bacteria Protein Interactions Reveals Conserved Domains and Motifs That Mediate Fundamental Infection Pathways

    Article • International Journal of Molecular Sciences, September 2022, MDPI AG

    Dr Marc Torrent Burgas

  17. A high‐throughput approach to predict A‐to‐I effects on RNA structure indicates a change of double‐stranded content in noncoding RNAs

    Article • IUBMB Life, September 2022, Wiley

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  18. Examining Topoisomers of a Snake-Venom-Derived Peptide for Improved Antimicrobial and Antitumoral Properties

    Article • Biomedicines, August 2022, MDPI AG

    Dr Marc Torrent Burgas

  19. Essential Role of Enzymatic Activity in the Leishmanicidal Mechanism of the Eosinophil Cationic Protein (RNase 3)

    Article • ACS Infectious Diseases, June 2022, American Chemical Society (ACS)

    Dr Marc Torrent Burgas

  20. In Vivo Evaluation of ECP Peptide Analogues for the Treatment of Acinetobacter baumannii Infection

    Article • Biomedicines, February 2022, MDPI AG

    Dr Marc Torrent Burgas

  21. HPIPred: Host–pathogen interactome prediction with phenotypic scoring

    Article • Computational and Structural Biotechnology Journal, January 2022, Elsevier

    Dr Marc Torrent Burgas

  22. Rationally Modified Antimicrobial Peptides from the N-Terminal Domain of Human RNase 3 Show Exceptional Serum Stability

    Article • Journal of Medicinal Chemistry, August 2021, American Chemical Society (ACS)

    Dr Marc Torrent Burgas

  23. The Interplay Between Disordered Regions in RNAs and Proteins Modulates Interactions Within Stress Granules and Processing Bodies

    Article • Journal of Molecular Biology, July 2021, Elsevier

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  24. Time-Resolved Transcriptional Profiling of Epithelial Cells Infected by Intracellular Acinetobacter baumannii

    Article • Microorganisms, February 2021, MDPI AG

    Dr Marc Torrent Burgas

  25. Bacteria use structural imperfect mimicry to hijack the host interactome

    Article • PLoS Computational Biology, December 2020, PLOS

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  26. Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model

    Article • Cellular and Molecular Life Sciences, November 2020, Springer Science + Business Media

    Dr Marc Torrent Burgas

  27. DualSeqDB: the host–pathogen dual RNA sequencing database for infection processes

    Article • Nucleic Acids Research, October 2020, Oxford University Press (OUP)

    Dr Marc Torrent Burgas

  28. RNA-binding and prion domains: the Yin and Yang of phase separation

    Article • Nucleic Acids Research, August 2020, Oxford University Press (OUP)

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  29. BacFITBase: a database to assess the relevance of bacterial genes during host infection

    Article • Nucleic Acids Research, October 2019, Oxford University Press (OUP)

    Dr Marc Torrent Burgas

  30. Insight into the Antifungal Mechanism of Action of Human RNase N-terminus Derived Peptides

    Article • International Journal of Molecular Sciences, September 2019, MDPI AG

    Dr Marc Torrent Burgas

  31. A Coordinated Response at The Transcriptome and Interactome Level is Required to Ensure Uropathogenic Escherichia coli Survival during Bacteremia

    Article • Microorganisms, August 2019, MDPI AG

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  32. The fitness cost and benefit of phase‐separated protein deposits

    Article • Molecular Systems Biology, April 2019, EMBO

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  33. Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions

    Article • Science Signaling, September 2018, American Association for the Advancement of Science

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas

  34. Positional scanning library applied to the human eosinophil cationic protein/RNase3 N-terminus reveals novel and potent anti-biofilm peptides

    Article • European Journal of Medicinal Chemistry, May 2018, Elsevier

    Dr Marc Torrent Burgas

  35. Structural similarities in the CPC clip motif explain peptide-binding promiscuity between glycosaminoglycans and lipopolysaccharides

    Article • Journal of The Royal Society Interface, November 2017, Royal Society Publishing

    Dr Marc Torrent Burgas

  36. Centrality in the host–pathogen interactome is associated with pathogen fitness during infection

    Article • Nature Communications, January 2017, Nature

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas

  37. Structural basis for endotoxin neutralization by the eosinophil cationic protein

    Article • European Journal of Biochemistry, October 2016, Wiley

    Dr David Pulido-Gomez, Dr Marc Torrent Burgas

  38. Biofilm erradication by eosinophil cationic protein

    Article • Antimicrobial Agents and Chemotherapy, August 2016, ASM Journals

    Dr David Pulido-Gomez, Dr Marc Torrent Burgas

  39. Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation

    Article • International Journal of Molecular Sciences, April 2016, MDPI AG

    Dr Marc Torrent Burgas

  40. Is membrane homeostasis the missing link between inflammation and neurodegenerative diseases?

    Article • Cellular and Molecular Life Sciences, September 2015, Springer Science + Business Media

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas

  41. Prediction of Bioactive Peptides Using Artificial Neural Networks

    Article • November 2014, Springer Science + Business Media

    Dr Marc Torrent Burgas

  42. Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus

    Article • Biochemical Journal, November 2013, Portland Press Ltd.

    Dr Marc Torrent Burgas

  43. Towards the rational design of antimicrobial proteins

    Article • European Journal of Biochemistry, October 2013, Wiley

    Dr Marc Torrent Burgas

  44. Two Human Host Defense Ribonucleases against Mycobacteria, the Eosinophil Cationic Protein (RNase 3) and RNase 7

    Article • Antimicrobial Agents and Chemotherapy, May 2013, ASM Journals

    Dr Marc Torrent Burgas

  45. Exploring New Biological Functions of Amyloids: Bacteria Cell Agglutination Mediated by Host Protein Aggregation

    Article • PLoS Pathogens, November 2012, PLOS

    Dr Marc Torrent Burgas

  46. Evolutionary selection for protein aggregation

    Article • Biochemical Society Transactions, October 2012, Portland Press Ltd.

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas

  47. The “CPC Clip Motif”: A Conserved Structural Signature for Heparin-Binding Proteins

    Article • PLOS One, August 2012, PLOS

    Dr Marc Torrent Burgas

  48. Discovering New In Silico Tools for Antimicrobial Peptide Prediction

    Article • Current Drug Targets, July 2012, Bentham Science Publishers

    Dr Marc Torrent Burgas

  49. Antimicrobial Peptide Action on Parasites

    Article • Current Drug Targets, July 2012, Bentham Science Publishers

    Dr Marc Torrent Burgas

  50. Antimicrobial Action and Cell Agglutination by the Eosinophil Cationic Protein Are Modulated by the Cell Wall Lipopolysaccharide Structure

    Article • Antimicrobial Agents and Chemotherapy, February 2012, ASM Journals

    Dr Marc Torrent Burgas

  51. Structural determinants of the eosinophil cationic protein antimicrobial activity

    Article • Biological Chemistry, January 2012, De Gruyter

    Dr Marc Torrent Burgas

  52. Lipopolysaccharide Neutralization by Antimicrobial Peptides: A Gambit in the Innate Host Defense Strategy

    Article • Journal of Innate Immunity, January 2012, Karger Publishers

    Dr Marc Torrent Burgas

  53. AMPA: an automated web server for prediction of protein antimicrobial regions

    Article • Bioinformatics, November 2011, Oxford University Press (OUP)

    Dr Marc Torrent Burgas

  54. The Generation of Antimicrobial Peptide Activity: A Trade-off between Charge and Aggregation?

    Article • Angewandte Chemie, September 2011, Wiley

    Dr Marc Torrent Burgas

  55. The Generation of Antimicrobial Peptide Activity: A Trade-off between Charge and Aggregation?

    Article • Angewandte Chemie, September 2011, Wiley

    Dr Marc Torrent Burgas

  56. Refining the Eosinophil Cationic Protein Antibacterial Pharmacophore by Rational Structure Minimization

    Article • Journal of Medicinal Chemistry, July 2011, American Chemical Society (ACS)

    Dr Marc Torrent Burgas

  57. The role of Gram-negative envelope LPS on the bactericidal properties of proteins and peptides: the case of eosinophil cationic protein

    Article • July 2011, World Scientific Pub Co Pte Lt

    Dr Marc Torrent Burgas

  58. Towards the rational design of antimicrobial peptides: Recent developments in computational tools

    Article • July 2011, World Scientific Pub Co Pte Lt

    Dr Marc Torrent Burgas

  59. Connecting Peptide Physicochemical and Antimicrobial Properties by a Rational Prediction Model

    Article • PLOS One, February 2011, PLOS

    Dr Marc Torrent Burgas

  60. Mapping the eosinophil cationic protein antimicrobial activity by chemical and enzymatic cleavage

    Article • Biochimie, February 2011, Elsevier

    Dr Marc Torrent Burgas

  61. Eosinophil Cationic Protein Aggregation: Identification of an N-Terminus Amyloid Prone Region

    Article • Biomacromolecules, August 2010, American Chemical Society (ACS)

    Dr Marc Torrent Burgas

  62. Eosinophil cationic protein (ECP) can bind heparin and other glycosaminoglycans through its RNase active site

    Article • Journal of Molecular Recognition, March 2010, Wiley

    Dr Marc Torrent Burgas

  63. Comparison of human RNase 3 and RNase 7 bactericidal action at the Gram-negative and Gram-positive bacterial cell wall

    Article • European Journal of Biochemistry, February 2010, Wiley

    Dr Marc Torrent Burgas

  64. Bactericidal and membrane disruption activities of the eosinophil cationic protein are largely retained in an N-terminal fragment

    Article • Biochemical Journal, August 2009, Portland Press Ltd.

    Dr Marc Torrent Burgas

  65. Comparison of the membrane interaction mechanism of two antimicrobial RNases: RNase 3/ECP and RNase 7

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, May 2009, Elsevier

    Dr Marc Torrent Burgas

  66. A theoretical approach to spot active regions in antimicrobial proteins

    Article • BMC Bioinformatics, January 2009, Springer Science + Business Media

    Dr Marc Torrent Burgas

  67. The Antipathogen Activities of Eosinophil Cationic Protein

    Article • Current Pharmaceutical Biotechnology, June 2008, Bentham Science Publishers

    Dr Marc Torrent Burgas

  68. Eosinophil Cationic Protein High-Affinity Binding to Bacteria-Wall Lipopolysaccharides and Peptidoglycans†

    Article • Biochemistry, March 2008, American Chemical Society (ACS)

    Dr Marc Torrent Burgas

  69. Topography Studies on the Membrane Interaction Mechanism of the Eosinophil Cationic Protein †

    Article • Biochemistry, January 2007, American Chemical Society (ACS)

    Dr Marc Torrent Burgas