All Stories

  1. Exogenous prion-like proteins and their potential to trigger cognitive dysfunction

    Article • Molecular Systems Biology, May 2025, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  2. catGRANULE 2.0: accurate predictions of liquid-liquid phase separating proteins at single amino acid resolution

    Article • Genome Biology, February 2025, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  3. Exogenous Amyloid Sequences: Their Role in Amyloid-Beta Heterotypic Aggregation

    Article • January 2025, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot

  4. RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding

    Article • Chemical Reviews, April 2024, American Chemical Society (ACS)

    Dr Natalia Sanchez de Groot

  5. Microbiome-Derived Prion-Like Proteins and Their Potential to Trigger Cognitive Dysfunction

    Article • October 2023, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot

  6. Aβ40 Aggregation under Changeable Conditions

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Dr Natalia Sanchez de Groot

  7. The PRALINE database: protein and Rna humAn singLe nucleotIde variaNts in condEnsates

    Article • Bioinformatics, January 2023, Oxford University Press (OUP)

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  8. The PRALINE database: Protein and Rna humAn singLe nucleotIde variaNts in condEnsates

    Article • December 2022, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot

  9. A high‐throughput approach to predict A‐to‐I effects on RNA structure indicates a change of double‐stranded content in noncoding RNAs

    Article • IUBMB Life, September 2022, Wiley

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  10. Microbiome Impact on Amyloidogenesis

    Article • Frontiers in Molecular Biosciences, June 2022, Frontiers

    Dr Natalia Sanchez de Groot

  11. The Interplay Between Disordered Regions in RNAs and Proteins Modulates Interactions Within Stress Granules and Processing Bodies

    Article • Journal of Molecular Biology, July 2021, Elsevier

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  12. Interplay between disordered regions in RNAs and proteins modulates interactions within stress granules and processing bodies

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot

  13. RNA‐protein interactions: Central players in coordination of regulatory networks

    Article • BioEssays, December 2020, Wiley

    Dr Natalia Sanchez de Groot

  14. Bacteria use structural imperfect mimicry to hijack the host interactome

    Article • PLoS Computational Biology, December 2020, PLOS

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  15. RNA-binding and prion domains: the Yin and Yang of phase separation

    Article • Nucleic Acids Research, August 2020, Oxford University Press (OUP)

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  16. Bacteria Use Structural Imperfect Mimicry To Hijack The Host Interactome

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot

  17. RNA-Binding and Prion Domains: The Yin and Yang of Phase Separation

    Article • January 2020, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot

  18. A Coordinated Response at The Transcriptome and Interactome Level is Required to Ensure Uropathogenic Escherichia coli Survival during Bacteremia

    Article • Microorganisms, August 2019, MDPI AG

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  19. RNA structure drives interaction with proteins

    Article • Nature Communications, July 2019, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  20. The fitness cost and benefit of phase‐separated protein deposits

    Article • Molecular Systems Biology, April 2019, EMBO

    Dr Marc Torrent Burgas, Dr Natalia Sanchez de Groot

  21. RNA as a key factor in driving or preventing self-assembly of the TAR DNA-binding protein 43

    Article • Journal of Molecular Biology, April 2019, Elsevier

    Dr Natalia Sanchez de Groot

  22. The fitness cost and benefit of phase separated protein deposits

    Article • March 2019, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot

  23. Insights into the structure-driven protein interactivity of RNA molecules

    Article • October 2018, Cold Spring Harbor Laboratory Press

    Dr Natalia Sanchez de Groot

  24. Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions

    Article • Science Signaling, September 2018, American Association for the Advancement of Science

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas

  25. Discovering Putative Prion-Like Proteins in Plasmodium falciparum: A Computational and Experimental Analysis

    Article • Frontiers in Microbiology, August 2018, Frontiers

    Dr Natalia Sanchez de Groot

  26. Characterization of Soft Amyloid Cores in Human Prion-Like Proteins

    Article • Scientific Reports, September 2017, Nature

    Dr Natalia Sanchez de Groot

  27. Constraints and consequences of the emergence of amino acid repeats in eukaryotic proteins

    Article • Nature Structural & Molecular Biology, August 2017, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  28. Protein aggregation into insoluble deposits protects from oxidative stress

    Article • Redox Biology, August 2017, Elsevier

    Dr Natalia Sanchez de Groot

  29. Centrality in the host–pathogen interactome is associated with pathogen fitness during infection

    Article • Nature Communications, January 2017, Nature

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas

  30. Characterization of Amyloid Cores in Prion Domains

    Article • Scientific Reports, September 2016, Nature

    Dr Natalia Sanchez de Groot

  31. Advances in the characterization of RNA-binding proteins

    Article • Wiley Interdisciplinary Reviews - RNA, August 2016, Wiley

    Dr Natalia Sanchez de Groot

  32. Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation

    Article • International Journal of Molecular Sciences, June 2016, MDPI AG

    Dr Natalia Sanchez de Groot

  33. Affinity and competition for TBP are molecular determinants of gene expression noise

    Article • Nature Communications, February 2016, Nature

    Dr Natalia Sanchez de Groot

  34. Prion-like proteins in bacteria

    Article • Frontiers in Microbiology, October 2015, Frontiers

    Dr Natalia Sanchez de Groot

  35. Is membrane homeostasis the missing link between inflammation and neurodegenerative diseases?

    Article • Cellular and Molecular Life Sciences, September 2015, Springer Science + Business Media

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas

  36. Structural and Computational Insights into Conformational Diseases: A Review

    Article • February 2015, Bentham Science Publishers

    Dr Natalia Sanchez de Groot

  37. Frontiers in Medicinal Chemistry

    Article • February 2015, Bentham Science Publishers

    Atta ur Rahman, Dr Natalia Sanchez de Groot

  38. Proteome response at the edge of protein aggregation

    Article • Open Biology, February 2015, Royal Society Publishing

    Dr Natalia Sanchez de Groot

  39. Intrinsically Disordered Segments Affect Protein Half-Life in the Cell and during Evolution

    Article • Cell Reports, September 2014, Elsevier

    Dr Natalia Sanchez de Groot

  40. INTRINSICALLY DISORDERED PROTEINS: REGULATION AND DISEASE

    Article • February 2013, World Scientific Pub Co Pte Lt

    Dr Natalia Sanchez de Groot

  41. Evolutionary selection for protein aggregation

    Article • Biochemical Society Transactions, October 2012, Portland Press Ltd.

    Dr Natalia Sanchez de Groot, Dr Marc Torrent Burgas

  42. The Effect of Amyloidogenic Peptides on Bacterial Aging Correlates with Their Intrinsic Aggregation Propensity

    Article • Journal of Molecular Biology, August 2012, Elsevier

    Dr Natalia Sanchez de Groot

  43. Using bacterial inclusion bodies to screen for amyloid aggregation inhibitors

    Article • Microbial Cell Factories, January 2012, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  44. Contribution of Disulfide Bonds to Stability, Folding, and Amyloid Fibril Formation: The PI3-SH3 Domain Case

    Article • Antioxidants & Redox Signaling, January 2012, Mary Ann Liebert Inc

    Dr Natalia Sanchez de Groot

  45. AGGRESCAN: Method, Application, and Perspectives for Drug Design

    Article • November 2011, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  46. Intrinsically disordered proteins: regulation and disease

    Article • Current Opinion in Structural Biology, June 2011, Elsevier

    Dr Natalia Sanchez de Groot

  47. Biological role of bacterial inclusion bodies: a model for amyloid aggregation

    Article • European Journal of Biochemistry, May 2011, Wiley

    Dr Natalia Sanchez de Groot

  48. Linking amyloid protein aggregation and yeast survival

    Article • Molecular BioSystems, January 2011, Royal Society of Chemistry

    Dr Natalia Sanchez de Groot

  49. The Role of Protein Sequence and Amino Acid Composition in Amyloid Formation: Scrambling and Backward Reading of IAPP Amyloid Fibrils

    Article • Journal of Molecular Biology, November 2010, Elsevier

    Dr Natalia Sanchez de Groot

  50. Modulation of Aβ42 fibrillogenesis by glycosaminoglycan structure

    Article • The FASEB Journal, November 2010, Federation of American Societies For Experimental Biology (FASEB)

    Dr Natalia Sanchez de Groot

  51. Protein folding and aggregation in bacteria

    Article • Cellular and Molecular Life Sciences, April 2010, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  52. Protein Aggregation Profile of the Bacterial Cytosol

    Article • PLOS One, February 2010, PLOS

    Dr Natalia Sanchez de Groot

  53. Amyloids in bacterial inclusion bodies

    Article • Trends in Biochemical Sciences, August 2009, Elsevier

    Dr Natalia Sanchez de Groot

  54. Design, Selection, and Characterization of Thioflavin-Based Intercalation Compounds with Metal Chelating Properties for Application in Alzheimer’s Disease

    Article • Journal of the American Chemical Society, February 2009, American Chemical Society (ACS)

    Dr Natalia Sanchez de Groot

  55. Studies on bacterial inclusion bodies

    Article • Future Microbiology, August 2008, Future Medicine

    Dr Natalia Sanchez de Groot

  56. Recent Structural and Computational Insights into Conformational Diseases

    Article • Current Medicinal Chemistry, June 2008, Bentham Science Publishers

    Dr Natalia Sanchez de Groot

  57. The in Vivo and in Vitro Aggregation Properties of Globular Proteins Correlate With Their Conformational Stability: The SH3 Case

    Article • Journal of Molecular Biology, May 2008, Elsevier

    Dr Natalia Sanchez de Groot

  58. Prion and Non-prion Amyloids of the HET-s Prion forming Domain

    Article • Journal of Molecular Biology, July 2007, Elsevier

    Dr Natalia Sanchez de Groot

  59. Ile-Phe Dipeptide Self-Assembly: Clues to Amyloid Formation

    Article • Biophysical Journal, March 2007, Elsevier

    Dr Natalia Sanchez de Groot

  60. AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides

    Article • BMC Bioinformatics, January 2007, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  61. Effect of temperature on protein quality in bacterial inclusion bodies

    Article • FEBS Letters, November 2006, Wiley

    Dr Natalia Sanchez de Groot

  62. Protein aggregation into bacterial inclusion bodies is a specific kinetically driven process

    Article • Microbial Cell Factories, October 2006, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  63. Protein activity in bacterial inclusion bodies correlates with predicted aggregation rates

    Article • Journal of Biotechnology, August 2006, Elsevier

    Dr Natalia Sanchez de Groot

  64. Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities

    Article • European Journal of Biochemistry, February 2006, Wiley

    Dr Natalia Sanchez de Groot

  65. Prediction of "hot spots" of aggregation in disease-linked polypeptides

    Article • BMC Structural Biology, January 2005, Springer Science + Business Media

    Dr Natalia Sanchez de Groot

  66. Amyloid fibril formation by bovine cytochromec

    Article • Spectroscopy An International Journal, January 2005, Hindawi Publishing Corporation

    Dr Natalia Sanchez de Groot