All Stories

  1. Evolutionary remodeling of a remnant GET pathway factor into PEX38, an essential peroxin

    Article • Proceedings of the National Academy of Sciences, February 2026, Proceedings of the National Academy of Sciences

    Prof Martin Jung

  2. Evolutionary Remodelling of a Remnant GET-Pathway Factor into PEX38, a Novel and Essential Peroxin in Euglenozoa

    Article • November 2025, openRxiv

    Prof Martin Jung

  3. Assessing the potential of bacterial signal peptides for radiopharmaceutical applications

    Article • Scientific Reports, September 2025, Springer Science + Business Media

    Prof Martin Jung

  4. Distinct Flower signaling domains orchestrate cellular fitness via secreted vesicles in Aβ-induced neurodegeneration

    Article • August 2025, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  5. A protein-specific priority code in presequences determines the efficiency of mitochondrial protein import

    Article • PLoS Biology, July 2025, PLOS

    Prof Martin Jung

  6. Polyclonal antibodies towards abrin and ricin—design and potential application for mass spectrometry-based analysis of human biosamples

    Article • Archives of Toxicology, July 2025, Springer Science + Business Media

    Prof Martin Jung

  7. Characterization of the putative yeast mitochondrial triacylglycerol lipase Tgl2

    Article • Journal of Biological Chemistry, March 2025, Elsevier

    Prof Martin Jung

  8. Characterization of Tgl2, a putative lipase in yeast mitochondria

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  9. The conserved membrane-proximal domain of Sbh1/ Sec61β guides signal peptides into the Sec61 channel

    Article • March 2024, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  10. Radiometal Complexes as Pharmacokinetic Modifiers: A Potent 68Ga-Labeled Gastrin-Releasing Peptide Receptor Antagonist Based on the Macrocyclic Metal Chelator NODIA-Me

    Article • Molecular Pharmaceutics, November 2023, American Chemical Society (ACS)

    Prof Martin Jung

  11. Quantitative Mass Spectrometry Characterizes Client Spectra of Components for Targeting of Membrane Proteins to and Their Insertion into the Membrane of the Human ER

    Article • International Journal of Molecular Sciences, September 2023, MDPI AG

    Prof Martin Jung

  12. Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes

    Article • Frontiers in Cell and Developmental Biology, August 2023, Frontiers

    Prof Martin Jung

  13. A novel PEX14/PEX5 interface links peroxisomal protein import and receptor recycling

    Article • August 2023, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  14. Rabconnectin-3α/DMXL2 Is Locally Enriched at the Synaptic Ribbon of Rod Photoreceptor Synapses

    Article • Cells, June 2023, MDPI AG

    Prof Martin Jung

  15. The 3q Oncogene SEC62 Predicts Response to Neoadjuvant Chemotherapy and Regulates Tumor Cell Migration in Triple Negative Breast Cancer

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Prof Martin Jung

  16. Immunohistochemistry Reveals TRPC Channels in the Human Hearing Organ—A Novel CT-Guided Approach to the Cochlea

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Prof Martin Jung

  17. Abstract P6-14-18: Effect of 3q oncogene SEC62 on migration and proliferation of triple-negative breast cancer cells

    Article • Cancer Research, March 2023, American Association for Cancer Research (AACR)

    Prof Martin Jung

  18. Co-chaperones of the Human Endoplasmic Reticulum: An Update

    Article • December 2022, Springer Science + Business Media

    Prof Martin Jung

  19. Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein Targeting

    Article • Cells, September 2022, MDPI AG

    Prof Martin Jung, Dr Sarah O'Keefe

  20. Signal Peptide Features Determining the Substrate Specificities of Targeting and Translocation Components in Human ER Protein Import

    Article • Frontiers in Physiology, July 2022, Frontiers

    Prof Martin Jung

  21. Ciliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses

    Article • International Journal of Molecular Sciences, June 2022, MDPI AG

    Prof Martin Jung, Dr Stephan Maxeiner

  22. The influence of terminal amine groups in close proximity to the metal chelator in peptide derived radiopharmaceuticals on the radiolabelling with 68Ga and 64Cu

    Article • Nuclear Medicine and Biology, May 2022, Elsevier

    Prof Martin Jung

  23. Proteomics identifies substrates and a novel component in hSnd2-dependent ER protein targeting

    Article • April 2022, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  24. TRPC6 Is Found in Distinct Compartments of the Human Kidney

    Article • International Journal of Translational Medicine, April 2022, MDPI AG

    Prof Martin Jung

  25. The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria

    Article • Journal of Molecular Medicine, April 2022, Springer Science + Business Media

    Prof Martin Jung

  26. Broad domains of histone marks in the highly compact Paramecium macronuclear genome

    Article • Genome Research, March 2022, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  27. The multi-factor modulated biogenesis of the mitochondrial multi-span protein Om14

    Article • Journal of Cell Biology, March 2022, Rockefeller University Press

    Prof Martin Jung

  28. RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons

    Article • Frontiers in Molecular Neuroscience, January 2022, Frontiers

    Prof Martin Jung, Dr Stephan Maxeiner

  29. Phenylbutyrate rescues the transport defect of the Sec61α mutations V67G and T185A for renin

    Article • Life Science Alliance, January 2022, Life Science Alliance, LLC

    Prof Martin Jung

  30. Dissecting the interactions of PINK1 with the TOM complex in depolarized mitochondria

    Article • January 2022, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  31. A unified model for the biogenesis of mitochondrial outer membrane multi-span proteins

    Article • December 2021, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  32. Anti-FGFR3 antibody epitopes are functional sites and correlate with the neuropathy pattern

    Article • Journal of Neuroimmunology, December 2021, Elsevier

    Prof Martin Jung

  33. Remodelling of Ca2+ homeostasis is linked to enlarged endoplasmic reticulum in secretory cells

    Article • Cell Calcium, November 2021, Elsevier

    Prof Martin Jung

  34. Two Piwis with Ago-like functions silence somatic genes at the chromatin level

    Article • RNA Biology, October 2021, Taylor & Francis

    Prof Martin Jung

  35. Lights, Camera, Interaction: Studying Protein–Protein Interactions of the ER Protein Translocase in Living Cells

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Prof Martin Jung

  36. Broad domains of histone marks in the highly compact Paramecium macronuclear genome

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  37. Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility

    Article • Journal of Molecular Biology, March 2021, Elsevier

    Prof Martin Jung

  38. The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor

    Article • Journal of Biological Chemistry, January 2021, Elsevier

    Prof Martin Jung

  39. Disturbed Presynaptic Ca2+ Signaling in Photoreceptors in the EAE Mouse Model of Multiple Sclerosis

    Article • iScience, December 2020, Elsevier

    Prof Martin Jung

  40. Two Piwis with Ago-like functions silence somatic genes at the chromatin level

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  41. 14-3-3 Proteins and Other Candidates form Protein-Protein Interactions with the Cytosolic C-terminal End of SOS1 Affecting Its Transport Activity

    Article • International Journal of Molecular Sciences, May 2020, MDPI AG

    Prof Martin Jung

  42. Alternative splicing switches STIM1 targeting to specialized membrane contact sites and modifies SOCE

    Article • March 2020, Cold Spring Harbor Laboratory Press

    Prof Martin Jung

  43. Amino Acids 563–566 of the Na+/H+ Exchanger Isoform 1 C-Terminal Cytosolic Tail Prevent Protein Degradation and Stabilize Protein Expression and Activity

    Article • International Journal of Molecular Sciences, March 2020, MDPI AG

    Prof Martin Jung

  44. Evolutionary divergent PEX3 is essential for glycosome biogenesis and survival of trypanosomatid parasites

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 2019, Elsevier

    Prof Martin Jung

  45. Defective cell adhesion function of solute transporter, SLC4A11, in endothelial corneal dystrophies

    Article • Human Molecular Genetics, November 2019, Oxford University Press (OUP)

    Prof Martin Jung

  46. Expression of the LRRC52 γ subunit (γ2) may provide Ca2+-independent activation of BK currents in mouse inner hair cells

    Article • The FASEB Journal, November 2019, Federation of American Societies For Experimental Biology (FASEB)

    Prof Martin Jung

  47. The kidney anion exchanger 1 affects tight junction properties via claudin-4

    Article • Scientific Reports, February 2019, Springer Science + Business Media

    Prof Martin Jung

  48. The Role of Plastidic Trigger Factor Serving Protein Biogenesis in Green Algae and Land Plants

    Article • PLANT PHYSIOLOGY, January 2019, American Society of Plant Biologists (ASPB)

    Prof Martin Jung

  49. Identification of Inhibitory Ca2+ Binding Sites in the Upper Vestibule of the Yeast Vacuolar TRP Channel

    Article • iScience, January 2019, Elsevier

    Prof Martin Jung

  50. AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum

    Article • Nature Communications, August 2018, Springer Science + Business Media

    Prof Martin Jung

  51. A mechanism for exocytotic arrest by the Complexin C-terminus

    Article • eLife, July 2018, eLife

    Prof Martin Jung

  52. Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR

    Article • Nucleic Acids Research, July 2018, Oxford University Press (OUP)

    Prof Martin Jung

  53. Ca 2+ -dependent regulation and binding of calmodulin to multiple sites of Transient Receptor Potential Melastatin 3 (TRPM3) ion channels

    Article • Cell Calcium, July 2018, Elsevier

    Prof Martin Jung

  54. Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences

    Article • Journal of Cell Biology, January 2018, Rockefeller University Press

    Prof Martin Jung

  55. Alternative Protein Targeting Pathway

    Article • FEBS Letters, September 2017, Wiley

    Prof Martin Jung

  56. Structural basis for substrate selection by the translocation and assembly module of the β-barrel assembly machinery

    Article • Molecular Microbiology, August 2017, Wiley

    Professor Trevor Lithgow, Prof Martin Jung

  57. The SND proteins constitute an alternative targeting route to the endoplasmic reticulum

    Article • Nature, November 2016, Springer Science + Business Media

    Prof Martin Jung

  58. ER-phagy and recovER-phag: SEC62-mediated endoplasmic reticulum turnover on recovery from ER stress

    Article • Nature Cell Biology, October 2016, Springer Science + Business Media

    Maurizio Molinari, Prof Martin Jung

  59. Strain-specific Loss of Formyl Peptide Receptor 3 in the Murine Vomeronasal and Immune Systems

    Article • Journal of Biological Chemistry, March 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Martin Jung

  60. Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidase

    Article • Molecular Biology of the Cell, July 2015, American Society for Cell Biology (ASCB)

    Prof Martin Jung

  61. Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum

    Article • Journal of Biological Chemistry, June 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Martin Jung

  62. A STIM2 splice variant negatively regulates store-operated calcium entry

    Article • Nature Communications, April 2015, Springer Science + Business Media

    Prof Martin Jung

  63. Increased water flux induced by an aquaporin-1/carbonic anhydrase II interaction

    Article • Molecular Biology of the Cell, March 2015, American Society for Cell Biology (ASCB)

    Prof Martin Jung

  64. Protein Transport into the Human Endoplasmic Reticulum

    Article • Journal of Molecular Biology, March 2015, Elsevier

    Prof Martin Jung

  65. Secretion and Immunogenicity of the Meningioma-Associated Antigen TXNDC16

    Article • The Journal of Immunology, August 2014, The American Association of Immunologists

    Prof Martin Jung

  66. Syntaxin11 serves as a t‐ SNARE for the fusion of lytic granules in human cytotoxic T lymphocytes

    Article • European Journal of Immunology, December 2013, Wiley

    Prof Martin Jung

  67. Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells

    Article • BMC Cancer, December 2013, Springer Science + Business Media

    Prof Martin Jung

  68. A Novel Pex14 Protein-interacting Site of Human Pex5 Is Critical for Matrix Protein Import into Peroxisomes

    Article • Journal of Biological Chemistry, November 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Martin Jung

  69. Interaction ofPseudomonas aeruginosaExotoxin A with the human Sec61 complex suppresses passive calcium efflux from the endoplasmic reticulum

    Article • Channels, October 2013, Taylor & Francis

    Prof Martin Jung

  70. The Role of Djp1 in Import of the Mitochondrial Protein Mim1 Demonstrates Specificity between a Cochaperone and Its Substrate Protein

    Article • Molecular and Cellular Biology, August 2013, ASM Journals

    Prof Martin Jung

  71. Different Munc13 Isoforms Function as Priming Factors in Lytic Granule Release from Murine Cytotoxic T Lymphocytes

    Article • Traffic, May 2013, Wiley

    Prof Martin Jung

  72. CK2 phosphorylation of human Sec63 regulates its interaction with Sec62

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 2013, Elsevier

    Prof Martin Jung

  73. BiP-mediated closing of the Sec61 channel limits Ca2+leakage from the ER

    Article • The EMBO Journal, July 2012, Wiley

    Prof Martin Jung

  74. Ca2+-calmodulin inhibits tail-anchored protein insertion into the mammalian endoplasmic reticulum membrane

    Article • FEBS Letters, October 2011, Wiley

    Prof Martin Jung

  75. A Monoclonal Antibody for in vivo Detection of Peroxisome-associated PTS1 Receptor

    Article • Hybridoma, August 2011, Mary Ann Liebert Inc

    Prof Martin Jung

  76. Calmodulin regulation of the calcium-leak channel Sec61 is unique to vertebrates

    Article • Channels, July 2011, Taylor & Francis

    Prof Martin Jung

  77. Sec61 complexes form ubiquitous ER Ca2+leak channels

    Article • Channels, May 2011, Taylor & Francis

    Prof Martin Jung

  78. Interaction of calmodulin with Sec61α limits Ca2+leakage from the endoplasmic reticulum

    Article • The EMBO Journal, November 2010, Wiley

    Prof Martin Jung

  79. The mammalian and yeast translocon complexes comprise a characteristic Sec61 channel

    Article • Biochemical and Biophysical Research Communications, June 2010, Elsevier

    Prof Martin Jung

  80. Evolutionary Gain of Function for the ER Membrane Protein Sec62 from Yeast to Humans

    Article • Molecular Biology of the Cell, March 2010, American Society for Cell Biology (ASCB)

    Prof Martin Jung, Erik L Snapp

  81. Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7

    Article • PROTEOMICS, July 2009, Wiley

    Prof Martin Jung

  82. Lanthanum ions inhibit the mammalian Sec61 complex in its channel dynamics and protein transport activity

    Article • FEBS Letters, June 2009, Wiley

    Prof Martin Jung

  83. 501 DIFFERENTIAL OVEREXPRESSION OF THE ENDOPLASMIC RETICULUM PROTEIN TLOC1/SEC62P AS A NOVEL PARAMETER IN PROSTATE CANCER DIAGNOSIS

    Article • European Urology Supplements, March 2007, Elsevier

    Prof Martin Jung

  84. Altered expression of β-catenin/E-cadherin in meningiomas

    Article • Histopathology, August 2006, Wiley

    Prof Martin Jung

  85. Approaches to the isolation and characterization of molecular chaperones

    Article • Protein Expression and Purification, March 2006, Elsevier

    Prof Martin Jung

  86. Genomic and Expression Analysis of the 3q25-q26 Amplification Unit Reveals TLOC1/SEC62 as a Probable Target Gene in Prostate Cancer

    Article • Molecular Cancer Research, March 2006, American Association for Cancer Research (AACR)

    Prof Martin Jung

  87. Characterization of the human GARP (Golgi associated retrograde protein) complex

    Article • Experimental Cell Research, May 2005, Elsevier

    Prof Martin Jung

  88. Protein transport into canine pancreatic microsomes

    Article • FEBS Journal, July 2004, Wiley

    Prof Martin Jung

  89. Characterization of pancreatic ERj3p, ahomolog of yeast DnaJ-like protein Scj1p

    Article • Biological Chemistry, January 2004, De Gruyter

    Prof Martin Jung

  90. The Sec61p Complex Is a Dynamic Precursor Activated Channel

    Article • Molecular Cell, July 2003, Elsevier

    Prof Martin Jung

  91. Transport of the Intracisternal A-Type Particle Gag Polyprotein to the Endoplasmic Reticulum Is Mediated by the Signal Recognition Particle

    Article • Journal of Virology, June 2003, ASM Journals

    Prof Martin Jung

  92. Tail-anchored and Signal-anchored Proteins Utilize Overlapping Pathways during Membrane Insertion

    Article • Journal of Biological Chemistry, December 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Martin Jung

  93. Article • Molecular and Cellular Biochemistry, January 2001, Springer Science + Business Media

    Prof Martin Jung

  94. A general mechanism for regulation of access to the translocon: Competition for a membrane attachment site on ribosomes

    Article • Proceedings of the National Academy of Sciences, November 1998, Proceedings of the National Academy of Sciences

    Prof Martin Jung

  95. Protein extracts from the gut wall influence the postnatal development of rat myenteric neurons in vitro

    Article • Neuroscience Letters, March 1998, Elsevier

    Prof Martin Jung

  96. Analysis of the catalytic site of the actin ADP-ribosylating Clostridium perfringens iota toxin

    Article • FEBS Letters, February 1996, Wiley

    Prof Martin Jung

  97. Active Site Mutation of the C3-like ADP-Ribosyltransferase from Clostridium limosumAnalysis of Glutamic Acid 174,

    Article • Biochemistry, January 1996, American Chemical Society (ACS)

    Prof Martin Jung

  98. ADP-Ribosyltransferase Type A from Turkey Erythrocytes Modifies Actin at Arg-95 and Arg-372

    Article • Biochemistry, January 1995, American Chemical Society (ACS)

    Prof Martin Jung

  99. Rho-ADP-ribosylating exoenzyme from Bacillus cereus. Purification, characterization, and identification of the NAD-binding site

    Article • Biochemistry, January 1995, American Chemical Society (ACS)

    Prof Martin Jung

  100. Studies on the active-site structure of C3-like exoenzymes: Involvement of glutamic acid in catalysis of ADP-ribosylation

    Article • Biochimie, January 1995, Elsevier

    Prof Martin Jung