All Stories

  1. Assessing the potential of bacterial signal peptides for radiopharmaceutical applications
  2. Distinct Flower signaling domains orchestrate cellular fitness via secreted vesicles in Aβ-induced neurodegeneration
  3. A protein-specific priority code in presequences determines the efficiency of mitochondrial protein import
  4. Polyclonal antibodies towards abrin and ricin—design and potential application for mass spectrometry-based analysis of human biosamples
  5. Characterization of the putative yeast mitochondrial triacylglycerol lipase Tgl2
  6. Characterization of Tgl2, a putative lipase in yeast mitochondria
  7. The conserved membrane-proximal domain of Sbh1/ Sec61β guides signal peptides into the Sec61 channel
  8. Radiometal Complexes as Pharmacokinetic Modifiers: A Potent 68Ga-Labeled Gastrin-Releasing Peptide Receptor Antagonist Based on the Macrocyclic Metal Chelator NODIA-Me
  9. Quantitative Mass Spectrometry Characterizes Client Spectra of Components for Targeting of Membrane Proteins to and Their Insertion into the Membrane of the Human ER
  10. Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes
  11. A novel PEX14/PEX5 interface links peroxisomal protein import and receptor recycling
  12. Rabconnectin-3α/DMXL2 Is Locally Enriched at the Synaptic Ribbon of Rod Photoreceptor Synapses
  13. The 3q Oncogene SEC62 Predicts Response to Neoadjuvant Chemotherapy and Regulates Tumor Cell Migration in Triple Negative Breast Cancer
  14. Immunohistochemistry Reveals TRPC Channels in the Human Hearing Organ—A Novel CT-Guided Approach to the Cochlea
  15. Abstract P6-14-18: Effect of 3q oncogene SEC62 on migration and proliferation of triple-negative breast cancer cells
  16. Co-chaperones of the Human Endoplasmic Reticulum: An Update
  17. Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein Targeting
  18. Signal Peptide Features Determining the Substrate Specificities of Targeting and Translocation Components in Human ER Protein Import
  19. Ciliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses
  20. The influence of terminal amine groups in close proximity to the metal chelator in peptide derived radiopharmaceuticals on the radiolabelling with 68Ga and 64Cu
  21. Proteomics identifies substrates and a novel component in hSnd2-dependent ER protein targeting
  22. TRPC6 Is Found in Distinct Compartments of the Human Kidney
  23. The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria
  24. Broad domains of histone marks in the highly compact Paramecium macronuclear genome
  25. The multi-factor modulated biogenesis of the mitochondrial multi-span protein Om14
  26. RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons
  27. Phenylbutyrate rescues the transport defect of the Sec61α mutations V67G and T185A for renin
  28. Dissecting the interactions of PINK1 with the TOM complex in depolarized mitochondria
  29. A unified model for the biogenesis of mitochondrial outer membrane multi-span proteins
  30. Anti-FGFR3 antibody epitopes are functional sites and correlate with the neuropathy pattern
  31. Remodelling of Ca2+ homeostasis is linked to enlarged endoplasmic reticulum in secretory cells
  32. Two Piwis with Ago-like functions silence somatic genes at the chromatin level
  33. Lights, Camera, Interaction: Studying Protein–Protein Interactions of the ER Protein Translocase in Living Cells
  34. Broad domains of histone marks in the highly compact Paramecium macronuclear genome
  35. Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility
  36. The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
  37. Disturbed Presynaptic Ca2+ Signaling in Photoreceptors in the EAE Mouse Model of Multiple Sclerosis
  38. Two Piwis with Ago-like functions silence somatic genes at the chromatin level
  39. 14-3-3 Proteins and Other Candidates form Protein-Protein Interactions with the Cytosolic C-terminal End of SOS1 Affecting Its Transport Activity
  40. Alternative splicing switches STIM1 targeting to specialized membrane contact sites and modifies SOCE
  41. Amino Acids 563–566 of the Na+/H+ Exchanger Isoform 1 C-Terminal Cytosolic Tail Prevent Protein Degradation and Stabilize Protein Expression and Activity
  42. Evolutionary divergent PEX3 is essential for glycosome biogenesis and survival of trypanosomatid parasites
  43. Defective cell adhesion function of solute transporter, SLC4A11, in endothelial corneal dystrophies
  44. Expression of the LRRC52 γ subunit (γ2) may provide Ca2+-independent activation of BK currents in mouse inner hair cells
  45. The kidney anion exchanger 1 affects tight junction properties via claudin-4
  46. The Role of Plastidic Trigger Factor Serving Protein Biogenesis in Green Algae and Land Plants
  47. Identification of Inhibitory Ca2+ Binding Sites in the Upper Vestibule of the Yeast Vacuolar TRP Channel
  48. AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum
  49. A mechanism for exocytotic arrest by the Complexin C-terminus
  50. Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR
  51. Ca 2+ -dependent regulation and binding of calmodulin to multiple sites of Transient Receptor Potential Melastatin 3 (TRPM3) ion channels
  52. Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences
  53. Alternative Protein Targeting Pathway
  54. Structural basis for substrate selection by the translocation and assembly module of the β-barrel assembly machinery
  55. The SND proteins constitute an alternative targeting route to the endoplasmic reticulum
  56. ER-phagy and recovER-phag: SEC62-mediated endoplasmic reticulum turnover on recovery from ER stress
  57. Strain-specific Loss of Formyl Peptide Receptor 3 in the Murine Vomeronasal and Immune Systems
  58. Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidase
  59. Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum
  60. A STIM2 splice variant negatively regulates store-operated calcium entry
  61. Increased water flux induced by an aquaporin-1/carbonic anhydrase II interaction
  62. Protein Transport into the Human Endoplasmic Reticulum
  63. Secretion and Immunogenicity of the Meningioma-Associated Antigen TXNDC16
  64. Syntaxin11 serves as a t‐ SNARE for the fusion of lytic granules in human cytotoxic T lymphocytes
  65. Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells
  66. A Novel Pex14 Protein-interacting Site of Human Pex5 Is Critical for Matrix Protein Import into Peroxisomes
  67. Interaction ofPseudomonas aeruginosaExotoxin A with the human Sec61 complex suppresses passive calcium efflux from the endoplasmic reticulum
  68. The Role of Djp1 in Import of the Mitochondrial Protein Mim1 Demonstrates Specificity between a Cochaperone and Its Substrate Protein
  69. Different Munc13 Isoforms Function as Priming Factors in Lytic Granule Release from Murine Cytotoxic T Lymphocytes
  70. CK2 phosphorylation of human Sec63 regulates its interaction with Sec62
  71. BiP-mediated closing of the Sec61 channel limits Ca2+leakage from the ER
  72. Ca2+-calmodulin inhibits tail-anchored protein insertion into the mammalian endoplasmic reticulum membrane
  73. A Monoclonal Antibody for in vivo Detection of Peroxisome-associated PTS1 Receptor
  74. Calmodulin regulation of the calcium-leak channel Sec61 is unique to vertebrates
  75. Sec61 complexes form ubiquitous ER Ca2+leak channels
  76. Interaction of calmodulin with Sec61α limits Ca2+leakage from the endoplasmic reticulum
  77. The mammalian and yeast translocon complexes comprise a characteristic Sec61 channel
  78. Evolutionary Gain of Function for the ER Membrane Protein Sec62 from Yeast to Humans
  79. Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7
  80. Lanthanum ions inhibit the mammalian Sec61 complex in its channel dynamics and protein transport activity
  81. 501 DIFFERENTIAL OVEREXPRESSION OF THE ENDOPLASMIC RETICULUM PROTEIN TLOC1/SEC62P AS A NOVEL PARAMETER IN PROSTATE CANCER DIAGNOSIS
  82. Altered expression of β-catenin/E-cadherin in meningiomas
  83. Approaches to the isolation and characterization of molecular chaperones
  84. Genomic and Expression Analysis of the 3q25-q26 Amplification Unit Reveals TLOC1/SEC62 as a Probable Target Gene in Prostate Cancer
  85. Characterization of the human GARP (Golgi associated retrograde protein) complex
  86. Protein transport into canine pancreatic microsomes
  87. Characterization of pancreatic ERj3p, ahomolog of yeast DnaJ-like protein Scj1p
  88. The Sec61p Complex Is a Dynamic Precursor Activated Channel
  89. Transport of the Intracisternal A-Type Particle Gag Polyprotein to the Endoplasmic Reticulum Is Mediated by the Signal Recognition Particle
  90. Tail-anchored and Signal-anchored Proteins Utilize Overlapping Pathways during Membrane Insertion
  91. A general mechanism for regulation of access to the translocon: Competition for a membrane attachment site on ribosomes
  92. Protein extracts from the gut wall influence the postnatal development of rat myenteric neurons in vitro
  93. Analysis of the catalytic site of the actin ADP-ribosylating Clostridium perfringens iota toxin
  94. Active Site Mutation of the C3-like ADP-Ribosyltransferase from Clostridium limosumAnalysis of Glutamic Acid 174,
  95. ADP-Ribosyltransferase Type A from Turkey Erythrocytes Modifies Actin at Arg-95 and Arg-372
  96. Rho-ADP-ribosylating exoenzyme from Bacillus cereus. Purification, characterization, and identification of the NAD-binding site
  97. Studies on the active-site structure of C3-like exoenzymes: Involvement of glutamic acid in catalysis of ADP-ribosylation