All Stories

  1. CuET overcomes regorafenib resistance by inhibiting epithelial-mesenchymal transition through suppression of the ERK pathway in hepatocellular carcinoma
  2. Toward Practical Applications of Engineered Living Materials with Advanced Fabrication Techniques
  3. Structurally and mechanically tuned macroporous hydrogels for scalable mesenchymal stem cell–extracellular matrix spheroid production
  4. “Find Me” and “Eat Me” signals: tools to drive phagocytic processes for modulating antitumor immunity
  5. Ezetimibe inhibits the migration and invasion of triple‐negative breast cancer cells by targeting TGFβ2 and EMT
  6. MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway
  7. Ezetimibe inhibits triple-negative breast cancer proliferation and promotes cell cycle arrest by targeting the PDGFR/AKT pathway
  8. The impact of the gut microbiome on tumor immunotherapy: from mechanism to application strategies
  9. UBE2S promotes malignant properties via VHL/HIF‐1α and VHL/JAK2/STAT3 signaling pathways and decreases sensitivity to sorafenib in hepatocellular carcinoma
  10. Long-term functional maintenance of primary hepatocytes in vitro using macroporous hydrogels engineered through liquid-liquid phase separation
  11. A novel approach for the analysis of single-cell RNA sequencing identifies TMEM14B as a novel poor prognostic marker in hepatocellular carcinoma
  12. Hypoxia signaling in cancer: Implications for therapeutic interventions
  13. A novel approach for the analysis of single-cell RNA sequencing identifies TMEM14B as a novel poor prognostic marker in hepatocellular carcinoma
  14. Long-Term Functional Maintenance of Primary Hepatocytes in Vitro Using Macroporous Hydrogels Engineered Through Liquid-Liquid Phase Separation
  15. Long noncoding RNA SNHG4 promotes the malignant progression of hepatocellular carcinoma through the miR‐211‐5p/CREB5 axis
  16. CFDP1 promotes hepatocellular carcinoma progression through activating NEDD4/PTEN/PI3K/AKT signaling pathway
  17. Deep learning–based tumour segmentation and total metabolic tumour volume prediction in the prognosis of diffuse large B-cell lymphoma patients in 3D FDG-PET images
  18. An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade
  19. Recombinant adenovirus expressing the fusion protein PD1PVR improves CD8+ T cell-mediated antitumor efficacy with long-term tumor-specific immune surveillance in hepatocellular carcinoma
  20. Single‐cell RNA sequencing identify SDCBP in ACE2‐positive bronchial epithelial cells negatively correlates with COVID‐19 severity
  21. SphK2/S1P Promotes Metastasis of Triple-Negative Breast Cancer Through the PAK1/LIMK1/Cofilin1 Signaling Pathway
  22. PRRX1 deficiency induces mesenchymal‐epithelial transition through PITX2/miR‐200–dependent SLUG/CTNNB1 regulation in hepatocellular carcinoma
  23. Recombinant oncolytic adenovirus expressing a soluble PVR elicits long-term antitumor immune surveillance
  24. Enhanced antitumor efficacy of a novel oncolytic vaccinia virus encoding a fully monoclonal antibody against T-cell immunoglobulin and ITIM domain (TIGIT)
  25. Liraglutide activates nature killer cell-mediated antitumor responses by inhibiting IL-6/STAT3 signaling in hepatocellular carcinoma
  26. Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor
  27. Stretchable hydrogels with low hysteresis and anti-fatigue fracture based on polyprotein cross-linkers
  28. Targeting SphK2 Reverses Acquired Resistance of Regorafenib in Hepatocellular Carcinoma
  29. <p>DEP Domain-Containing Protein 1B (DEPDC1B) Promotes Migration and Invasion in Pancreatic Cancer Through the Rac1/PAK1-LIMK1-Cofilin1 Signaling Pathway</p>
  30. Targeting aerobic glycolysis by dichloroacetate improves Newcastle disease virus-mediated viro-immunotherapy in hepatocellular carcinoma
  31. Graphene oxide arms oncolytic measles virus for improved effectiveness of cancer therapy
  32. Dual effects of gossypol on human hepatocellular carcinoma via endoplasmic reticulum stress and autophagy
  33. IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wnt/β-catenin signaling
  34. A robust six-gene prognostic signature for prediction of both disease-free and overall survival in non-small cell lung cancer
  35. The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma
  36. CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma
  37. Targeted co-delivery of Beclin 1 siRNA and FTY720 to hepatocellular carcinoma by calcium phosphate nanoparticles for enhanced anticancer efficacy
  38. Rationally designed synthetic protein hydrogels with predictable mechanical properties
  39. Exosome-Mimetic Nanovesicles from Hepatocytes promote hepatocyte proliferation in vitro and liver regeneration in vivo
  40. Exosomal miR-665 as a novel minimally invasive biomarker for hepatocellular carcinoma diagnosis and prognosis
  41. Oncolytic measles virus enhances antitumour responses of adoptive CD8+NKG2D+ cells in hepatocellular carcinoma treatment
  42. Role of stem cell-derived exosomes in cancer
  43. Electrically Controllable Actuators Based on Supramolecular Peptide Hydrogels
  44. The Glutaminase-1 Inhibitor 968 Enhances Dihydroartemisinin-Mediated Antitumor Efficacy in Hepatocellular Carcinoma Cells
  45. Polymer‐Supramolecular Polymer Double‐Network Hydrogel
  46. Lenalidomide induces apoptosis and inhibits angiogenesis via caspase-3 and VEGF in hepatocellular carcinoma cells
  47. Exosomes derived from HCC cells induce sorafenib resistance in hepatocellular carcinoma both in vivo and in vitro
  48. A Highly Stretchable and Autonomous Self‐Healing Polymer Based on Combination of Pt···Pt and π–π Interactions
  49. Electroresponsive Supramolecular Graphene Oxide Hydrogels for Active Bacteria Adsorption and Removal
  50. Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and Apoptosis
  51. Hierarchical construction of a mechanically stable peptide–graphene oxide hybrid hydrogel for drug delivery and pulsatile triggered release in vivo
  52. Identification and Evaluation of Serum MicroRNA-29 Family for Glioma Screening
  53. Diverse roles of miR-29 in cancer (Review)
  54. Baicalein Induces Apoptosis and Autophagy via Endoplasmic Reticulum Stress in Hepatocellular Carcinoma Cells
  55. Hepatic Stellate Cell Coculture Enables Sorafenib Resistance in Huh7 Cells through HGF/c-Met/Akt and Jak2/Stat3 Pathways
  56. Roles of HIF-1 in hepatocellular carcinoma
  57. The Role of Hypoxia Inducible Factor-1 in Hepatocellular Carcinoma
  58. Associations of miR-499 and miR-34b/c Polymorphisms with Susceptibility to Hepatocellular Carcinoma: An Evidence-Based Evaluation
  59. Expression of Potential Cancer Stem Cell Marker ABCG2 is Associated with Malignant Behaviors of Hepatocellular Carcinoma
  60. Relationship between SIRT1 and tumors
  61. Dysregulation of signaling pathways and putative biomarkers in liver cancer stem cells (Review)
  62. A novel 7-O-modified genistein derivative with acetylcholinesterase inhibitory effect, estrogenic activity and neuroprotective effect
  63. The therapeutic effects of tectorigenin on chemically induced liver fibrosis in rats and an associated metabonomic investigation
  64. Lack of Association of Two Common Polymorphisms rs2910164 and rs11614913 with Susceptibility to Hepatocellular Carcinoma: A Meta-Analysis
  65. Pro-apoptotic effects of tectorigenin on human hepatocellular carcinoma HepG2 cells
  66. Tectorigenin inhibits the in vitro proliferation and enhances miR-338* expression of pulmonary fibroblasts in rats with idiopathic pulmonary fibrosis
  67. Cochliones A–D, four new tetrahydrochromanone derivatives from endophyticCochliobolussp.
  68. Cytotoxic Chaetoglobosins from the EndophyteChaetomium globosum
  69. ABCG2: A potential marker of stem cells and novel target in stem cell and cancer therapy
  70. Anti-proliferative and pro-apoptotic effects of tectorigenin on hepatic stellate cells
  71. Protective effect of hopeahainol A, a novel acetylcholinesterase inhibitor, on hydrogen peroxide-induced injury in PC12 cells
  72. Bioactive Alkaloids from Endophytic Aspergillus fumigatus
  73. Phenylmethanesulfonyl fluoride
  74. Laccase production by Monotospora sp., an endophytic fungus in Cynodon dactylon
  75. Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from Aloe vera var. chinensis