What is it about?

This work supports the evidence that cedrelone is able to kill triple negative breast tumor cancer (TNBC) dells and also to interfere with adhesion, migration and invasion of these cells.

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Why is it important?

It is imperative to take advantage of the huge Brazilian biodiversity to find new active compounds against different diseases, in special cancer. This study shows the effects of cedrelone, isolated from a native Brazilian plant, on TNBC cells, indicating that it is able to kill these cells. However, in vivo studies must confirm these effects in order to be able to confirm cedrelone as an anti-tumor chemotherapeutic agent.

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This page is a summary of: Effects of Limonoid Cedrelone on MDA-MB-231 Breast Tumor Cells in vitro, Anti-Cancer Agents in Medicinal Chemistry, December 2013, Bentham Science Publishers, DOI: 10.2174/18715206113139990314.
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