All Stories

  1. Mitochondrial quality in aging and neurodegeneration: The emerging role of mitochondria-derived vesicles
  2. Selective Silencing of TDP-43 P. G376D Mutation Reverses Key Amyotrophic Lateral Sclerosis-Related Cellular Deficits
  3. Neisseria meningitidis: a traditional extracellular pathogen with an intense intracellular lifestyle
  4. Propionic acid toxicity and utilization of α-ketobutyric acid in Neisseria meningitidis via the methylcitrate cycle under specific conditions
  5. Effects of surface-exposed sialic acid and LOS outer core on the ability of native Neisseria meningitidis outer membrane vesicles (nOMVs) to induce cytokine expression and pyroptotic pathways in THP-1-derived macrophages
  6. The Other Side of the Same Coin: Beyond the Coding Region in Amyotrophic Lateral Sclerosis
  7. Potential Role of Membrane Contact Sites in the Dysregulation of the Crosstalk Between Mitochondria and Lysosomes in Alzheimer’s Disease
  8. Circulating mitochondrial components and metabolic and inflammatory markers in Charcot-Marie-Tooth type 2B
  9. Induced mitochondrial deficit by NDUFS3 transient silencing reduces RAB7 expression and causes lysosomal dysfunction in pancreatic cancer cells
  10. Circulating Cell-Free Mitochondrial DNA and Inflammation in Older Adults with Pancreatic Cancer: Results from an Exploratory Study
  11. Dysfunctional Mitochondria Characterize Amyotrophic Lateral Sclerosis Patients’ Cells Carrying the p.G376D TARDBP Pathogenetic Substitution
  12. Lysosomal Dysfunction in Amyotrophic Lateral Sclerosis: A Familial Case Linked to the p.G376D TARDBP Mutation
  13. The Type III Intermediate Filament Protein Peripherin Regulates Lysosomal Degradation Activity and Autophagy
  14. Mitochondria break free: Mitochondria-derived vesicles in aging and associated conditions
  15. miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish
  16. Beyond Inflammation: Role of Pyroptosis Pathway Activation by Gram-Negative Bacteria and Their Outer Membrane Vesicles (OMVs) in the Interaction with the Host Cell
  17. In silico evidence that substitution of glycine for valine (p.G8V) in a common variant of TMPRSS2 isoform 1 increases accessibility to an endocytic signal: Implication for SARS-cov-2 entry into host cells and susceptibility to COVID-19
  18. Neisseria meningitidis activates pyroptotic pathways in a mouse model of meningitis: role of a two-partner secretion system
  19. Characterization of Chemoresistance in Pancreatic Cancer: A Look at MDR-1 Polymorphisms and Expression in Cancer Cells and Patients
  20. Dysregulation of a Subset of Circulating and Vesicle-Associated miRNA in Pancreatic Cancer
  21. Mitochondria-Derived Vesicles, Sterile Inflammation, and Pyroptosis in Liver Cancer: Partners in Crime or Innocent Bystanders?
  22. Defects of mitochondria-lysosomes communication induce secretion of mitochondria-derived vesicles and drive chemoresistance in ovarian cancer cells
  23. Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
  24. Antisense therapy: a potential breakthrough in the treatment of neurodegenerative diseases
  25. Mitochondrial-Derived Vesicles: The Good, the Bad, and the Ugly
  26. Mitochondrial-derived vesicles in skeletal muscle remodeling and adaptation
  27. The contribution of mitochondrial DNA alterations to aging, cancer, and neurodegeneration
  28. An aqueous olive leaf extract (OLE) ameliorates parameters of oxidative stress associated with lipid accumulation and induces lipophagy in human hepatic cells
  29. Endosome to Lysosome Transport
  30. Role of the Intermediate Filament Protein Peripherin in Health and Disease
  31. Allele-specific silencing as therapy for familial amyotrophic lateral sclerosis caused by the p.G376D TARDBP mutation
  32. Mitochondria dysfunction in Charcot Marie Tooth 2B Peripheral Sensory Neuropathy
  33. HrpA anchors meningococci to the dynein motor and affects the balance between apoptosis and pyroptosis
  34. Phenotyping of Fecal Microbiota of Winnie, a Rodent Model of Spontaneous Chronic Colitis, Reveals Specific Metabolic, Genotoxic, and Pro-inflammatory Properties
  35. Fully Automated Computational Approach for Precisely Measuring Organelle Acidification with Optical pH Sensors
  36. Circulating Mitochondrial DNA and Inter-Organelle Contact Sites in Aging and Associated Conditions
  37. Autophagy and Lysosomal Functionality in CMT2B Fibroblasts Carrying the RAB7K126R Mutation
  38. Circulating extracellular vesicles: friends and foes in neurodegeneration
  39. Mitochondrial Dysfunction, Protein Misfolding and Neuroinflammation in Parkinson’s Disease: Roads to Biomarker Discovery
  40. Extracellular Vesicles and Pancreatic Cancer: Insights on the Roles of miRNA, lncRNA, and Protein Cargos in Cancer Progression
  41. RAB7A Regulates Vimentin Phosphorylation through AKT and PAK
  42. Role of the V1G1 subunit of V-ATPase in breast cancer cell migration
  43. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
  44. Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein
  45. An altered lipid metabolism characterizes Charcot-Marie-Tooth type 2B peripheral neuropathy
  46. Extracellular Vesicles and Damage-Associated Molecular Patterns: A Pandora’s Box in Health and Disease
  47. Circulating Mitochondrial-Derived Vesicles, Inflammatory Biomarkers and Amino Acids in Older Adults With Physical Frailty and Sarcopenia: A Preliminary BIOSPHERE Multi-Marker Study Using Sequential and Orthogonalized Covariance Selection – Linear Discr...
  48. Role of EGFR in the Nervous System
  49. GSK-3-TSC axis governs lysosomal acidification through autophagy and endocytic pathways
  50. Generation and Release of Mitochondrial-Derived Vesicles in Health, Aging and Disease
  51. Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation
  52. Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature
  53. Alteration of the late endocytic pathway in Charcot–Marie–Tooth type 2B disease
  54. Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson’s Disease: Results from the EXosomes in PArkiNson’s Disease (EXPAND) Study
  55. Singlet oxygen photo-production by perylene bisimide derivative Langmuir-Schaefer films for photodynamic therapy applications
  56. Role of the RAB7 Protein in Tumor Progression and Cisplatin Chemoresistance
  57. Mitochondrial-Derived Vesicles as Candidate Biomarkers in Parkinson’s Disease: Rationale, Design and Methods of the EXosomes in PArkiNson Disease (EXPAND) Study
  58. Synergistic Effect of Mitochondrial and Lysosomal Dysfunction in Parkinson’s Disease
  59. Coordination between Rac1 and Rab Proteins: Functional Implications in Health and Disease
  60. Mitochondrial Dysfunction and Aging: Insights from the Analysis of Extracellular Vesicles
  61. Modulation of RAB7A Protein Expression Determines Resistance to Cisplatin through Late Endocytic Pathway Impairment and Extracellular Vesicular Secretion
  62. An SPR based immunoassay for the sensitive detection of the soluble epithelial marker E-cadherin
  63. Yeast Two‐Hybrid Assay to Identify Interacting Proteins
  64. Investigation of polydopamine coatings by X-ray Photoelectron Spectroscopy as an effective tool for improving biomolecule conjugation
  65. β-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy
  66. Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer
  67. Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B
  68. β-Catenin Knockdown Affects Mitochondrial Biogenesis and Lipid Metabolism in Breast Cancer Cells
  69. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A
  70. The paper characterizes the role of RILP in cell migration
  71. Platinum-induced mitochondrial DNA mutations confer lower sensitivity to paclitaxel by impairing tubulin cytoskeletal organization
  72. The article describes the role of Rab7 in the regulation of cell migration
  73. Luminescent CdSe@ZnS nanocrystals embedded in liposomes: a cytotoxicity study in HeLa cells
  74. A review that describes the role of Rab7 in several cellular processes
  75. Differentiation of renal stem cells on fibronectin
  76. Role of Intermediate Filaments in Vesicular Traffic
  77. Biocompatible multilayer capsules engineered with a graphene oxide derivative: synthesis, characterization and cellular uptake
  78. Endosome to Lysosome Transport
  79. Rab7 Regulates CDH1 Endocytosis, Circular Dorsal Ruffles Genesis, and Thyroglobulin Internalization in a Thyroid Cell Line
  80. Fitness Cost of Rifampin Resistance in Neisseria meningitidis:In VitroStudy of Mechanisms Associated withrpoBH553Y Mutation
  81. Advances in Use of Capsule-Based Fluorescent Sensors for Measuring Acidification of Endocytic Compartments in Cells with Altered Expression of V-ATPase Subunit V 1 G 1
  82. Two-hybrid-based systems: Powerful tools for investigation of membrane traffic machineries
  83. Repeated ER–endosome contacts promote endosome translocation and neurite outgrowth
  84. A new V-ATPase regulatory mechanism mediated by the Rab interacting lysosomal protein (RILP)
  85. The Role of Rab Proteins in Neuronal Cells and in the Trafficking of Neurotrophin Receptors
  86. The two-hybrid system: A powerful tool to dissect molecular mechanisms underlying membrane traffic diseases
  87. The Rab-interacting lysosomal protein (RILP) regulates vacuolar ATPase acting on the V1G1 subunit
  88. Serogroup-Specific Interaction of Neisseria meningitidis Capsular Polysaccharide with Host Cell Microtubules and Effects on Tubulin Polymerization
  89. Vimentin phosphorylation and assembly are regulated by the small GTPase Rab7a
  90. Dynamic Investigation of Interaction of Biocompatible Iron Oxide Nanoparticles with Epithelial Cells for Biomedical Applications
  91. Charcot–Marie–Tooth disease and intracellular traffic
  92. Molecular basis of Charcot–Marie–Tooth type 2B disease
  93. Charcot–Marie–Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin
  94. Dynamics of Rab7b-Dependent Transport of Sorting Receptors
  95. Rab7b and receptors trafficking
  96. CMT2B-associated Rab7 mutants inhibit neurite outgrowth
  97. Rab7b controls trafficking from endosomes to the TGN
  98. Mycobacterial Nucleoside Diphosphate Kinase Blocks Phagosome Maturation in Murine Raw 264.7 Macrophages
  99. Rab7 and the CMT2B disease
  100. The Meningococcal ABC-Type l-Glutamate Transporter GltT Is Necessary for the Development of Experimental Meningitis in Mice
  101. Abundant expression and purification of biologically active mitochondrial citrate carrier in baculovirus-infected insect cells
  102. Detection of Activated Rab7 GTPase with an Immobilized RILP Probe
  103. Long QT Syndrome–Associated Mutations in KCNQ1 and KCNE1 Subunits Disrupt Normal Endosomal Recycling of I Ks Channels
  104. The HrpB-HrpA two-partner secretion system is essential for intracellular survival ofNeisseria meningitidis
  105. Characterization of the Rab7K157N mutant protein associated with Charcot–Marie-Tooth type 2B
  106. Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease
  107. Chapter 6 Phagocytosis and Host–Pathogen Interactions in Dictyostelium with a Look at Macrophages
  108. Reverse transcriptase-PCR differential display analysis of meningococcal transcripts during infection of human cells: Up-regulation of priA and its role in intracellular replication
  109. RILP is required for the proper morphology and function of late endosomes
  110. Obelia (Cnidaria, Hydrozoa, Campanulariidae): a microphagous, filter-feeding medusa
  111. Mycobacterium bovis BCG disrupts the interaction of Rab7 with RILP contributing to inhibition of phagosome maturation
  112. The Neisseria meningitidis Capsule Is Important for Intracellular Survival in Human Cells
  113. Regulation of Endocytic Recycling of KCNQ1/KCNE1 Potassium Channels
  114. Rab5 and Rab7 Control Endocytic Sorting along the Axonal Retrograde Transport Pathway
  115. RILP interacts with the VPS22 component of the ESCRT-II complex
  116. Identification of a Meningococcal l-Glutamate ABC Transporter Operon Essential for Growth in Low-Sodium Environments
  117. Signal transduction gRABs attention
  118. The Small GTPase Rab7 Controls the Endosomal Trafficking and Neuritogenic Signaling of the Nerve Growth Factor Receptor TrkA
  119. The Rab-interacting lysosomal protein, a Rab7 and Rab34 effector, is capable of self-interaction
  120. Expression, Assay, and Functional Properties of RILP
  121. The unconventional myosin-VIIa associates with lysosomes
  122. Role for Rab7 in maturation of late autophagic vacuoles
  123. Salmonella Impairs RILP Recruitment to Rab7 during Maturation of Invasion Vacuoles
  124. Microtubule motors control membrane dynamics of Salmonella-containing vacuoles
  125. Endosomal trafficking of the Menkes copper ATPase ATP7A is mediated by vesicles containing the Rab7 and Rab5 GTPase proteins
  126. Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP
  127. Modulation of Rab5 and Rab7 Recruitment to Phagosomes by Phosphatidylinositol 3-Kinase
  128. A new inhibitor of the transcription–termination factor Rho
  129. Phenotypes of a Naturally Defective recB Allele in Neisseria meningitidis Clinical Isolates
  130. Rab Coupling Protein (RCP), a Novel Rab4 and Rab11 Effector Protein
  131. Identification, Characterization, and Variable Expression of a Naturally Occurring Inhibitor Protein of IS1106 Transposase in Clinical Isolates ofNeisseriameningitidis
  132. Expression Analysis and Chromosomal Assignment of PRA1 and RILP Genes
  133. Evolution and function of the neisserialdam-replacing gene
  134. Rab4 affects both recycling and degradative endosomal trafficking
  135. Rab‐interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes
  136. A New Vector for Insertion of Any DNA Fragment into the Chromosome of Transformable Neisseriae
  137. Rab7: A Key to Lysosome Biogenesis
  138. Direct interaction of EEA1 with Rab5b
  139. Intracistronic transcription termination in polysialyltransferase gene (siaD ) affects phase variation in Neisseria meningitidis
  140. The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro
  141. Interaction Cloning and Characterization of the cDNA Encoding the Human Prenylated Rab Acceptor (PRA1)
  142. Hypermutation in Pathogenic Bacteria
  143. Control of Rab5 and Rab7 Expression by the Isoprenoid Pathway
  144. Genetic mapping of the mouse Rab7 gene and pseudogene and of the human RAB7 homolog
  145. Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways induced by Ret
  146. Free fatty acids modulate LDL receptor activity in BHK-21 cells
  147. This paper described the role of Rab7 in controlling transport to late endosomes and lysosomes
  148. The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin
  149. Molecular Cloning and Expression Analysis of the Human Rab7 GTP-ase Complementary Deoxyribonucleic Acid
  150. Rab4b
  151. Rab7
  152. Rab5b and Rab5c
  153. Cloning and expression analysis of the murine Rab7 cDNA
  154. Cloning of the gene encoding TROP‐2, a cell‐surface glycoprotein expressed by human carcinomas
  155. Co-operative regulation of endocytosis by three RAB5 isoforms
  156. [19] Expression of Rab GTPases using recombinant vaccinia viruses
  157. [2] Purification of posttranslationally modified and unmodified Rab5 protein expressed in Spodoptera frugiperda cells
  158. Rab5a is a common component of the apical and basolateral endocytic machinery in polarized epithelial cells.
  159. MRC OX19 recognizes the rat CD5 surface glycoprotein, but does not provide evidence for a population of CD5bright B cells
  160. Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange
  161. Plasticity of early endosomes
  162. The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
  163. Molecular Cloning of the Rat CD5 Gene
  164. Immunofluorescence analysis in flow cytometry: better selection of antibody-labeled cells after fluorescence overcompensation in the red channel.
  165. Isolation and Partial Characterization of a New Gene (br1) Belonging to the Superfamily of the Small GTP-Binding Proteins
  166. Nucleotide sequence of a genomic fragment of the rat IGF-I gene spanning an alternate 5′ non coding exon
  167. A new member of therasgene superfamily identified in a rat liver cell line