All Stories

  1. Influence of short term storage conditions, concentration methods and excipients on extracellular vesicle recovery and function

    Article • European Journal of Pharmaceutics and Biopharmaceutics, January 2022, Elsevier

    Dr André Görgens

  2. Author Correction: GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

    Article • Nature Communications, December 2021, Springer Science + Business Media

    Dr André Görgens

  3. Growth Media Conditions Influence the Secretion Route and Release Levels of Engineered Extracellular Vesicles

    Article • Advanced Healthcare Materials, November 2021, Wiley

    Dr André Görgens

  4. GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

    Article • Nature Communications, November 2021, Springer Science + Business Media

    Dr André Görgens

  5. Diagnostic and Prognostic Utility of the Extracellular Vesicles Subpopulations Present in Pleural Effusion

    Article • Biomolecules, October 2021, MDPI AG

    Dr André Görgens

  6. Extracellular vesicles are the primary source of blood‐borne tumour‐derived mutant KRAS DNA early in pancreatic cancer

    Article • Journal of Extracellular Vesicles, October 2021, Wiley

    Dr André Görgens

  7. Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles

    Article • Nature Biomedical Engineering, September 2021, Springer Science + Business Media

    Dr André Görgens

  8. Human Cord Blood B Cells Differ from the Adult Counterpart by Conserved Ig Repertoires and Accelerated Response Dynamics

    Article • The Journal of Immunology, June 2021, The American Association of Immunologists

    Dr André Görgens

  9. Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway

    Article • Frontiers in Cell and Developmental Biology, May 2021, Frontiers

    Dr André Görgens

  10. Multiparametric Profiling of Single Nanoscale Extracellular Vesicles by Combined Atomic Force and Fluorescence Microscopy: Correlation and Heterogeneity in Their Molecular and Biophysical Features

    Article • Small, March 2021, Wiley

    Dr André Görgens

  11. Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification

    Article • Neuro-Oncology, January 2021, Oxford University Press (OUP)

    Dr André Görgens

  12. Multiparametric Profiling of Single Nanoscale Extracellular Vesicles by Combined Atomic Force and Fluorescence Microscopy: Correlation and Heterogeneity in Their Molecular and Biophysical Features

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Dr André Görgens

  13. Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle

    Article • Biomaterials, January 2021, Elsevier

    Dr André Görgens

  14. MIFlowCyt‐EV: The Next Chapter in the Reporting and Reliability of Single Extracellular Vesicle Flow Cytometry Experiments

    Article • Cytometry Part A, November 2020, Wiley

    Dr André Görgens

  15. Human Amnion Epithelial Cells Impair T Cell Proliferation: The Role of HLA-G and HLA-E Molecules

    Article • Cells, September 2020, MDPI AG

    Dr André Görgens

  16. Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging

    Article • Journal of Extracellular Vesicles, August 2020, Wiley

    Dr André Görgens

  17. Human neonatal B cell immunity differs from the adult version by conserved Ig repertoires and rapid, but transient response dynamics

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Dr André Görgens

  18. Engineering of extracellular vesicles for display of protein biotherapeutics

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Dr André Görgens

  19. Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Dr André Görgens

  20. Aiming to Compare Apples to Apples: Analysis of Extracellular Vesicles and Other Nanosized Particles by Flow Cytometry

    Article • Cytometry Part A, June 2020, Wiley

    Dr André Görgens

  21. High‐Resolution Imaging Flow Cytometry Reveals Impact of Incubation Temperature on Labeling of Extracellular Vesicles with Antibodies

    Article • Cytometry Part A, May 2020, Wiley

    Dr André Görgens

  22. Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells

    Article • Cancers, May 2020, MDPI AG

    Dr André Görgens

  23. Differential B-cell receptor signaling requirement for adhesion of mantle cell lymphoma cells to stromal cells

    Article • March 2020, Cold Spring Harbor Laboratory Press

    Dr André Görgens

  24. CpG stimulation of chronic lymphocytic leukemia cells induces a polarized cell shape and promotes migration in vitro and in vivo

    Article • PLoS ONE, February 2020, PLOS

    Dr André Görgens

  25. MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments

    Article • Journal of Extracellular Vesicles, January 2020, Taylor & Francis

    Dr André Görgens

  26. Extracellular Vesicles

    Article • January 2020, Springer Science + Business Media

    Dr André Görgens

  27. Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection

    Article • Journal of Extracellular Vesicles, January 2020, Taylor & Francis

    Dr André Görgens

  28. Analysis of individual extracellular vesicles by imaging flow cytometry

    Article • January 2020, Elsevier

    Dr André Görgens

  29. Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule – single vesicle level by fluorescence correlation spectroscopy and single particle imaging

    Article • Journal of Extracellular Vesicles, September 2019, Taylor & Francis

    Dr André Görgens

  30. Human multipotent hematopoietic progenitor cell expansion is neither supported in endothelial and endothelial/mesenchymal co-cultures nor in NSG mice

    Article • Scientific Reports, September 2019, Springer Science + Business Media

    Dr André Görgens

  31. Allogeneic transplantation of peripheral blood stem cell grafts results in a massive decrease of primitive hematopoietic progenitor frequencies in reconstituted bone marrows

    Article • Bone Marrow Transplantation, August 2019, Springer Science + Business Media

    Dr André Görgens

  32. Distinct Spatio-Temporal Dynamics of Tumor-Associated Neutrophils in Small Tumor Lesions

    Article • Frontiers in Immunology, June 2019, Frontiers

    Dr André Görgens

  33. Label-Free Surface Protein Profiling of Extracellular Vesicles by an Electrokinetic Sensor

    Article • ACS Sensors, May 2019, American Chemical Society (ACS)

    Dr André Görgens

  34. Analysis of single extracellular vesicles by imaging flow cytometry

    Article • Journal of Extracellular Vesicles, January 2019, Taylor & Francis

    Dr André Görgens, Joshua Welsh, Dr Chantal M Boulanger, Tobias Tertel

  35. Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours

    Article • Journal of Extracellular Vesicles, January 2019, Taylor & Francis

    Dr André Görgens, Lasse Dührsen

  36. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Article • Journal of Extracellular Vesicles, November 2018, Taylor & Francis

    A. Paula Domínguez Rubio, Dr Muhammad Nawaz, Dr. Kenneth W Witwer, Dr. Ann M Wehman, Dr André Görgens, Daniel Bachurski, Anna C. Beardi, Dr Scott M Langevin, Dr Johnathon D Anderson, Maja Kosanovic

  37. Translocation-generated ITK-FER and ITK-SYK fusions induce STAT3 phosphorylation and CD69 expression

    Article • Biochemical and Biophysical Research Communications, September 2018, Elsevier

    Dr André Görgens

  38. Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

    Article • Frontiers in Immunology, June 2018, Frontiers

    Dr André Görgens

  39. Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome

    Article • Haematologica, January 2018, Ferrata Storti Foundation (Haematologica)

    Dr André Görgens

  40. Enforced GFI1 expression impedes human and murine leukemic cell growth

    Article • Scientific Reports, November 2017, Nature

    Dr André Görgens

  41. A Therapeutic Antiviral Antibody Inhibits the Anterograde Directed Neuron-to-Cell Spread of Herpes Simplex Virus and Protects against Ocular Disease

    Article • Frontiers in Microbiology, October 2017, Frontiers

    Dr André Görgens

  42. Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography

    Article • Scientific Reports, September 2017, Nature

    Dr André Görgens

  43. Dissecting the origin of dendritic cell and macrophage subsets in human hematopoiesis

    Article • Experimental Hematology, September 2017, Elsevier

    Dr André Görgens

  44. In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem Cells

    Article • Stem Cell Reports, April 2017, Elsevier

    Dr André Görgens

  45. Webinar | Analysis of extracellular vesicles including exosomes by imaging flow cytometry

    Article • Science, June 2016, American Association for the Advancement of Science

    Dr André Görgens

  46. Lost in Transplantation? Unexpected shift from multipotent to late lymphomyeloid hematopoietic stem and progenitor cells in patients 1 year after hematopoietic stem cell transplantation

    Article • Bone Marrow Transplantation, May 2016, Nature

    Dr André Görgens

  47. Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML

    Article • Experimental Hematology, May 2016, Elsevier

    Dr André Görgens

  48. Superior therapeutic index in lymphoma therapy: CD30+ CD34+ hematopoietic stem cells resist a chimeric antigen receptor (CAR) T cell attack

    Article • Molecular Therapy, April 2016, Nature

    Dr André Görgens

  49. Circulating Tumor Cell Composition in Renal Cell Carcinoma

    Article • PLoS ONE, April 2016, PLOS

    Dr André Görgens

  50. GFI1 as a novel prognostic and therapeutic factor for AML/MDS

    Article • Leukemia, February 2016, Nature

    Dr André Görgens, Christian Thiede

  51. Human mesenchymal and murine stromal cells support human lympho-myeloid progenitor expansion but not maintenance of multipotent haematopoietic stem and progenitor cells

    Article • Cell Cycle, January 2016, Taylor & Francis

    Dr André Görgens

  52. Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper

    Article • Journal of Extracellular Vesicles, December 2015, Co-Action Publishing

    Dr André Görgens, Dr Lorenzo Fraile

  53. From Basic Biology to Engineering and Clinical Translation of Stem Cells: Meeting Report on the 8th International Meeting of the Stem Cell Network North Rhine Westphalia

    Article • Cellular Reprogramming, December 2015, Mary Ann Liebert Inc

    Dr André Görgens

  54. Concise Review: Asymmetric Cell Divisions in Stem Cell Biology

    Article • Symmetry, November 2015, MDPI AG

    Dr André Görgens

  55. CEACAM1-4L Promotes Anchorage-Independent Growth in Melanoma

    Article • Frontiers in Oncology, October 2015, Frontiers

    Dr André Görgens

  56. Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression

    Article • Stem Cells Translational Medicine, September 2015, Wiley

    Dr André Görgens

  57. Age-Related Increase of EED Expression in Early Hematopoietic Progenitor Cells is Associated with Global Increase of the Histone Modification H3K27me3

    Article • Stem Cells and Development, September 2015, Mary Ann Liebert Inc

    Dr André Görgens

  58. Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages

    Article • Stem Cell Reports, July 2015, Elsevier

    Dr André Görgens

  59. Wie unser Blut entsteht – neue Erkennt nisse zur Hämatopoese

    Article • BIOspektrum, May 2015, Springer Science + Business Media

    Dr André Görgens

  60. CD133 allows elaborated discrimination and quantification of haematopoietic progenitor subsets in human haematopoietic stem cell transplants

    Article • British Journal of Haematology, March 2015, Wiley

    Dr André Görgens

  61. Prevention of Herpes Simplex Virus Induced Stromal Keratitis by a Glycoprotein B-Specific Monoclonal Antibody

    Article • PLoS ONE, January 2015, PLOS

    Dr André Görgens

  62. Multipotent Hematopoietic Progenitors Divide Asymmetrically to Create Progenitors of the Lymphomyeloid and Erythromyeloid Lineages

    Article • Stem Cell Reports, December 2014, Elsevier

    Dr André Görgens

  63. New relationships of human hematopoietic lineages facilitate detection of multipotent hematopoietic stem and progenitor cells

    Article • Cell Cycle, November 2013, Taylor & Francis

    Dr André Görgens

  64. Revision of the Human Hematopoietic Tree: Granulocyte Subtypes Derive from Distinct Hematopoietic Lineages

    Article • Cell Reports, May 2013, Elsevier

    Dr André Görgens

  65. Abstract 4714: Vemurafenib reverses immunosuppression by myeloid derived suppressor cells.

    Article • Cancer Research, April 2013, American Association for Cancer Research (AACR)

    Dr André Görgens

  66. Vemurafenib reverses immunosuppression by myeloid derived suppressor cells

    Article • International Journal of Cancer, April 2013, Wiley

    Dr André Görgens

  67. Lipid raft redistribution and morphological cell polarization are separable processes providing a basis for hematopoietic stem and progenitor cell migration

    Article • The International Journal of Biochemistry & Cell Biology, July 2012, Elsevier

    Dr André Görgens

  68. Self-Renewal of Primitive Hematopoietic Cells: A Focus on Asymmetric Cell Division

    Article • December 2010, World Scientific Pub Co Pte Lt

    Dr André Görgens