All Stories

  1. Food for thought: why is there more airway smooth muscle in asthma?
  2. Molecular and Immunological Mechanisms Underlying the Various Pharmacological Properties of the Potent Bioflavonoid, Rutin
  3. Evidence from a mouse model on the dangers of thirdhand electronic cigarette exposure during early life
  4. Dietary Fatty Acids Amplify Inflammatory Responses to Infection through p38 MAPK Signaling
  5. Heightened response to e-cigarettes in COPD
  6. Short-chain fatty acids increase TNFα-induced inflammation in primary human lung mesenchymal cells through the activation of p38 MAPK
  7. Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD
  8. Modulation of neural regulators of energy homeostasis, and of inflammation, in the pups of mice exposed to e-cigarettes
  9. Heat or Burn? Impacts of Intrauterine Tobacco Smoke and E-Cigarette Vapor Exposure on the Offspring’s Health Outcome
  10. L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury
  11. Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells
  12. MitoQ supplementation prevent long-term impact of maternal smoking on renal development, oxidative stress and mitochondrial density in male mice offspring
  13. Maternal E-Cigarette Exposure in Mice Alters DNA Methylation and Lung Cytokine Expression in Offspring
  14. Evidence of Biomass Smoke Exposure as a Causative Factor for the Development of COPD
  15. Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c
  16. Effect of long-term maternal smoking on the offspring’s lung health
  17. Autophagy and airway fibrosis: Is there a link?
  18. Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers
  19. Periostin as a marker of mucosal remodelling in chronic rhinosinusitis
  20. The effect of non-specific tight junction modulators on the transepithelial transport of poorly permeable drugs across airway epithelial cells
  21. Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations
  22. Translational Aspects of the Human Respiratory Virome
  23. Biomass Smoke Exposure Enhances Rhinovirus-Induced Inflammation in Primary Lung Fibroblasts
  24. Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases
  25. Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition. Novel Role as a Protein Phosphatase 2A Activator
  26. Time-Based Measurement of Personal Mite Allergen Bioaerosol Exposure over 24 Hour Periods
  27. Impact of maternal cigarette smoke exposure on brain inflammation and oxidative stress in male mice offspring
  28. Asthma: Airways That Are Hyperactive by Design
  29. Effect of Sphingosine 1-Phosphate on Cyclo-Oxygenase-2 Expression, Prostaglandin E2Secretion, and β2-Adrenergic Receptor Desensitization
  30. Evaluation of Transbronchial Lung Cryobiopsy Size and Freezing Time: A Prognostic Animal Study
  31. IL-17A increases TNF-α-induced COX-2 protein stability and augments PGE2secretion from airway smooth muscle cells: impact on β2-adrenergic receptor desensitization
  32. Differential deposition of fibronectin by asthmatic bronchial epithelial cells
  33. Differential neutrophil activation in viral infections: Enhanced TLR-7/8-mediated CXCL8 release in asthma
  34. Absence of back to school peaks in human rhinovirus detections and respiratory symptoms in a cohort of children with asthma
  35. Using multiple online databases to help identify microRNAs regulating the airway epithelial cell response to a virus-like stimulus
  36. Doxycycline reduces the migration of tuberous sclerosis complex‐2 null cells ‐ effects on RhoA‐ GTP ase and focal adhesion kinase
  37. Mono- and Cocultures of Bronchial and Alveolar Epithelial Cells Respond Differently to Proinflammatory Stimuli and Their Modulation by Salbutamol and Budesonide
  38. Inhibitors of Phosphodiesterase 4, but Not Phosphodiesterase 3, Increase β2-Agonist–Induced Expression of Antiinflammatory Mitogen-Activated Protein Kinase Phosphatase 1 in Airway Smooth Muscle Cells
  39. Fibulin1C peptide induces cell attachment and extracellular matrix deposition in lung fibroblasts
  40. Do We Really Need to Keep Redesigning β2-agonists for the Management of Asthma?
  41. Rhinoviruses significantly affect day-to-day respiratory symptoms of children with asthma
  42. A ‘soft spot’ for drug transport: modulation of cell stiffness using fatty acids and its impact on drug transport in lung model
  43. Viral infections and asthma: an inflammatory interface?
  44. A Quantitative Proteomic Approach to Identify Significantly Altered Protein Networks in the Serum of Patients with Lymphangioleiomyomatosis (LAM)
  45. TLR2 activation causes tachyphylaxis to β2-agonistsin vitroandex vivo:modelling bacterial exacerbation
  46. Effects of cigarette smoke extract on human airway smooth muscle cells in COPD
  47. LF-15 & T7, Synthetic Peptides Derived from Tumstatin, Attenuate Aspects of Airway Remodelling in a Murine Model of Chronic OVA-Induced Allergic Airway Disease
  48. The Nucleotide-Binding Domain and Leucine-Rich Repeat Protein–3 Inflammasome Is Not Activated in Airway Smooth Muscle Upon Toll-Like Receptor–2 Ligation
  49. Airway smooth muscle CXCR3 ligand production: regulation by JAK-STAT1 and intracellular Ca2+
  50. A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
  51. Characterising the Mechanism of Airway Smooth Muscle β2 Adrenoceptor Desensitization by Rhinovirus Infected Bronchial Epithelial Cells
  52. Emerging mediators of airway smooth muscle dysfunction in asthma
  53. Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle
  54. Lamstatin - a novel inhibitor of lymphangiogenesis derived from collagen IV
  55. Comments on Point:Counterpoint: Alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma
  56. Prostaglandins but not leukotrienes alter extracellular matrix protein deposition and cytokine release in primary human airway smooth muscle cells and fibroblasts
  57. The phosphoinositide 3′-kinase p110δ modulates contractile protein production and IL-6 release in human airway smooth muscle
  58. CombinedHaemophilus influenzaerespiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma
  59. TGF-β enhances deposition of perlecan from COPD airway smooth muscle
  60. β2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers
  61. Beyond the Immune System: The Role of Resident Cells in Asthma and COPD
  62. Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study
  63. Matrix Proteins from Smoke-Exposed Fibroblasts Are Pro-proliferative
  64. What can in vitro models of COPD tell us?
  65. Doxycycline inhibits matrix metalloproteinase-2 secretion from TSC2-null mouse embryonic fibroblasts and lymphangioleiomyomatosis cells
  66. Rhinovirus infection induces extracellular matrix protein deposition in asthmatic and nonasthmatic airway smooth muscle cells
  67. β2-Agonist Induced cAMP Is Decreased in Asthmatic Airway Smooth Muscle Due to Increased PDE4D
  68. Phosphatidylinositol 3-Kinase Isoform-Specific Effects in Airway Mesenchymal Cell Function
  69. Effects of β2 Agonists, Corticosteroids, and Novel Therapies on Rhinovirus-Induced Cytokine Release and Rhinovirus Replication in Primary Airway Fibroblasts
  70. Fibulin-1 Is Increased in Asthma – A Novel Mediator of Airway Remodeling?
  71. Rhinovirus-Induced Exacerbations of Asthma
  72. Differential expression of peroxisome proliferator activated receptor γ and cyclin D1 does not affect proliferation of asthma- and non-asthma-derived airway smooth muscle cells
  73. Molecular Mechanisms of Combination Therapy With Inhaled Corticosteroids and Long-Acting β-Agonists
  74. Exhalation of respiratory viruses by breathing, coughing, and talking
  75. Dimethylfumarate inhibits NF-κB function at multiple levels to limit airway smooth muscle cell cytokine secretion
  76. Pulmonary Suppressor of Cytokine Signaling-1 Induced by IL-13 Regulates Allergic Asthma Phenotype
  77. Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages
  78. A New Method for Sampling and Detection of Exhaled Respiratory Virus Aerosols
  79. Airway Smooth Muscle and Asthma
  80. Whole blood endotoxin responsiveness in patients with chronic heart failure: the importance of serum lipoproteins
  81. Expression of mRNAs for DNA methyltransferases and methyl-CpG-binding proteins in the human female germ line, preimplantation embryos, and embryonic stem cells
  82. Regulation of protease-activated receptor-1 in mononuclear cells by neutrophil proteases
  83. Effect of acute and chronic inflammatory stimuli on expression of protease-activated receptors 1 and 2 in alveolar macrophages
  84. Isolation, characterization and expression of the human Factor In the Germline alpha (FIGLA) gene in ovarian follicles and oocytes