All Stories

  1. Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study...
  2. Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
  3. Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950–2023: a demographic analysis for the Global Burden of Disease Study 2023
  4. Extracellular vesicles in malaria pathogenesis and Therapy: Emerging insights and future perspectives
  5. The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
  6. Evaluation of Anticancer Potential in Human Colorectal Carcinoma HCT-116 Cellsby Fungal-Mediated Zinc Oxide Nanoparticles
  7. Computational mechanistic insight of fungal metabolites for novel acetylcholinesterase inhibitors
  8. Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023
  9. Molecular docking studies of some amino acid-sulfonamide conjugates as potential anticancer agents
  10. Exploring Alectinib and Irinotecan as potential human kallikrein-1 inhibitors: a drug repurposing approach for cancer and dermatological disorders
  11. Pathological interplay of NF-κB and M1 macrophages in chronic inflammatory lung diseases
  12. Chroman-Schiff base derivatives as potential Anti-Tubercular Agents: In silico studies, Synthesis, and Biological evaluation
  13. Exploring TGF-β signaling in benign prostatic hyperplasia: from cellular senescence to fibrosis and therapeutic implications
  14. Synthesis, in silico toxicity prediction, and in vitro antibacterial activity of new 4-amino-N-arylbenzenesulfonamide derivatives
  15. Polypharmacology and Neuroprotective Effects of Gingerol in Alzheimer’s Disease
  16. Design, Synthesis, Computational Studies, and Evaluation of Triazole Acetamide Linked with Phenyl Piperazine Derivatives as Anticancer Agents Against Breast Cancer
  17. Exosomes in infectious diseases: insights into leishmaniasis pathogenesis, immune modulation, and therapeutic potential
  18. Non-coding RNAs in meningitis: Key regulators of immune response and inflammation
  19. Exploring hypoxia-induced ncRNAs as biomarkers and therapeutic targets in lung cancer
  20. An Extensive Computational Investigation of Mycobacterium tuberculosis Pantothenate Synthetase Inhibitors from Diverse‐Lib Compounds Library
  21. Immunotherapy in Alzheimer’s Disease: Current Status and Future Directions
  22. In-vitro enzyme inhibition, kinetics, molecular docking and dynamics simulation approaches to decoding the mechanism of Ficus virens in cholinesterase inhibition
  23. Cannabidiol and neurodegeneration: From molecular mechanisms to clinical benefits
  24. From diagnosis to therapy: The critical role of lncRNAs in hepatoblastoma
  25. Investigating the Potential Therapeutic Mechanisms of Puerarin in Neurological Diseases
  26. Mechanistic insights into the potential role of dietary polyphenols and their nanoformulation in the management of Alzheimer’s disease
  27. Recent Advances in Drug Delivery Systems Targeting Insulin Signalling for the Treatment of Alzheimer’s Disease
  28. Beyond the genome: MALAT1's role in advancing urologic cancer care
  29. In-silico and in-vitro evaluation of antifungal bioactive compounds from Streptomyces sp. strain 130 against Aspergillus flavus
  30. Investigation of natural compounds as methyltransferase inhibitors against dengue virus: an in silico approach
  31. Emergence of taurine as a therapeutic agent for neurological disorders
  32. Biological Synthesis, Characterization, and Therapeutic Potential of S. commune-Mediated Gold Nanoparticles
  33. Potential role of Albizia lebbeck and Emblica officinalis on smooth muscle contractions in experimental animal models
  34. Resveratrol-Laden Nano-Systems in the Cancer Environment: Views and Reviews
  35. Nanotechnology-Based Drug Delivery Approaches of Mangiferin: Promises, Reality and Challenges in Cancer Chemotherapy
  36. Repurposing Anti-Dengue Compounds against Monkeypox Virus Targeting Core Cysteine Protease
  37. Combinatorial drug‐loaded quality by design adapted transliposome gel formulation for dermal delivery: In vitro and dermatokinetic study
  38. Highlights on the Development, Related Patents, and Prospects of Lenacapavir: The First-in-Class HIV-1 Capsid Inhibitor for the Treatment of Multi-Drug-Resistant HIV-1 Infection
  39. Role of Natural Products in the Management of COVID-19: A Saudi Arabian Perspective
  40. Ex Vivo Antiplatelet and Thrombolytic Activity of Bioactive Fractions from the New-Fangled Stem Buds of Ficus religiosa L. with Simultaneous GC-MS Examination
  41. Cancer theranostics employing microneedles: Experimental and patented strategies
  42. Nanotheranostics to target antibiotic-resistant bacteria: Strategies and applications
  43. Myco-Synthesis of Silver Nanoparticles and Their Bioactive Role against Pathogenic Microbes
  44. Multitargeted Virtual Screening and Molecular Simulation of Natural Product-like Compounds against GSK3β, NMDA-Receptor, and BACE-1 for the Management of Alzheimer’s Disease
  45. Harnessing natural polysaccharides-based nanoparticles for oral delivery of phytochemicals: Knocking down the barriers
  46. Computer-assisted discovery of safe and effective DprE1/ aaRSs Inhibitors against TB utilizing Drug Repurposing approach
  47. Annotation of Potential Vaccine Targets and Designing of mRNA-Based Multi-Epitope Vaccine against Lumpy Skin Disease Virus via Reverse Vaccinology and Agent-Based Modeling
  48. Flavonol-Glycoside and Rare Triterpenoid Derivatives Isolated from Leaves of Combretum glutinosum Perr. Ex Dc. with In Vitro Cytotoxic Activity
  49. Valorization of Adhatoda vasica leaves: Extraction, in vitro analyses and in silico approaches
  50. Development and Evaluation of Novel Encapsulated Isoeugenol-Liposomal Gel Carrier System for Methicillin-Resistant Staphylococcus aureus
  51. Antibacterial efficacy of synthesized silver nanoparticles of Microbacterium proteolyticum LA2(R) and Streptomyces rochei LA2(O) against biofilm forming meningitis causing microbes
  52. Wound Healing Activity of the Flavonoid-Enriched Fraction of Selaginella bryopteris Linn. against Streptozocin-Induced Diabetes in Rats
  53. Preparation and Evaluation of Nanoemulsion of Citronella Essential Oil with Improved Antimicrobial and Anti-Cancer Properties
  54. Caraway Oil as a Multimodal Therapy for Neuropathic Pain: Investigating the Mechanisms of Action in Rats with Chronic Constriction Injury
  55. Synthesis and Biological Evaluation of Octahydroquinazolinones as Phospholipase A2, and Protease Inhibitors: Experimental and Theoretical Exploration
  56. Intranasal Delivery of a Silymarin Loaded Microemulsion for the Effective Treatment of Parkinson’s Disease in Rats: Formulation, Optimization, Characterization, and In Vivo Evaluation
  57. Identifying bioactive phytoconstituents as C-terminal Src kinase inhibitors: a virtual screening and molecular simulation approach
  58. Nano-Enabled Strategies for the Treatment of Lung Cancer: Potential Bottlenecks and Future Perspectives
  59. An Immunoinformatics Approach to Design Novel and Potent Multi-Epitope-Based Vaccine to Target Lumpy Skin Disease
  60. Formulation, In Vitro and In Silico Evaluations of Anise (Pimpinella anisum L.) Essential Oil Emulgel with Improved Antimicrobial Effects
  61. Husk-like Zinc Oxide Nanoparticles Induce Apoptosis through ROS Generation in Epidermoid Carcinoma Cells: Effect of Incubation Period on Sol-Gel Synthesis and Anti-Cancerous Properties
  62. Oral Brincidofovir Therapy for Monkeypox Outbreak: A Focused Review on the Therapeutic Potential, Clinical Studies, Patent Literature, and Prospects
  63. Comparative Proteomics and Genome-Wide Druggability Analyses Prioritized Promising Therapeutic Targets against Drug-Resistant Leishmania tropica
  64. Discovering Gummadiol and Isoarboreol as potential inhibitors of sphingosine kinase 1: virtual screening and MD simulation studies
  65. Composition, Antibacterial Efficacy, and Anticancer Activity of Essential Oil Extracted from Psidium guajava (L.) Leaves
  66. Camptothecin loaded nano-delivery systems in the cancer therapeutic domains: A critical examination of the literature
  67. Nanoplatform for the Delivery of Topotecan in the Cancer Milieu: An Appraisal of its Therapeutic Efficacy
  68. Potential Antioxidant Activity of Apigenin in the Obviating Stress-Mediated Depressive Symptoms of Experimental Mice
  69. Nanodelivery of Dietary Polyphenols for Therapeutic Applications
  70. Laxative Effects and Phytochemical Analysis of Perilla frutescens Seed Oil by Using Gas Chromatography: A Good Source of Omega Fatty Acids
  71. Laboratory determination and thermodynamic analysis of alendronate solubility in supercritical carbon dioxide
  72. Citrus Essential Oils in Aromatherapy: Therapeutic Effects and Mechanisms
  73. MmpL3 Inhibition as a Promising Approach to Develop Novel Therapies against Tuberculosis: A Spotlight on SQ109, Clinical Studies, and Patents Literature
  74. Protective Effect of Zingiber officinale Rhizomes Against Experimental Induced Ulcers in Diabetic Rats
  75. ROCK2 inhibition: A futuristic approach for the management of Alzheimer’s disease
  76. Selenium and COVID-19: A spotlight on the clinical trials, inventive compositions, and patent literature
  77. Theoretical investigation on optimization of biodiesel production using waste cooking oil: Machine learning modeling and experimental validation
  78. Development of advanced method based on nanoporous membranes for separation of pharmaceutical compounds from aqueous streams: Computational simulation and analysis
  79. Solubility Enhancement, Formulation Development, and Antibacterial Activity of Xanthan-Gum-Stabilized Colloidal Gold Nanogel of Hesperidin against Proteus vulgaris
  80. An insight into the discovery, clinical studies, compositions, and patents of macozinone: A drug targeting the DprE1 enzyme of Mycobacterium tuberculosis
  81. New Thiazole Acetic Acid Derivatives: A Study to Screen Cardiovascular Activity Using Isolated Rat Hearts and Blood Vessels
  82. Recent developments, challenges and future prospects in advanced drug delivery systems in the management of tuberculosis
  83. A Glance at the Development and Patent Literature of Tecovirimat: The First-in-Class Therapy for Emerging Monkeypox Outbreak
  84. Stachytarpheta cayennensis-mediated copper nanoparticles shows anticancer activity in both in vitro and in vivo models
  85. The role of thiazole acetate derivatives on isolated heart and blood vessels in experimental rats
  86. Computational simulation using machine learning models in prediction of CO2 absorption in environmental applications
  87. Antimycobacterial Evaluation and Microwave-Assisted Synthesis of N-(5-methyl-4-oxo-2-arylthiazolidin-3-yl) Isonicotinamide Derivatives
  88. Computational prediction of drug solubility in supercritical carbon dioxide: Thermodynamic and artificial intelligence modeling
  89. The Therapeutic and Prophylactic Potential of Quercetin against COVID-19: An Outlook on the Clinical Studies, Inventive Compositions, and Patent Literature
  90. Nigella sativa L. and COVID-19: A Glance at The Anti-COVID-19 Chemical Constituents, Clinical Trials, Inventions, and Patent Literature
  91. State-of-the-Art Review on the Application of Membrane Bioreactors for Molecular Micro-Contaminant Removal from Aquatic Environment
  92. Burden of COVID-19: a preliminary analysis in the population of Saudi Arabia
  93. Obviation of dyslipidemia by garlic oil and its organosulfur compound, diallyl disulphide, in experimental animals
  94. Bovine bone-derived natural hydroxyapatite-supported ZnCl2 as a sustainable high efficiency heterogeneous biocatalyst for synthesizing amidoalkyl naphthols
  95. Plumbagin Alleviates Intracerebroventricular-Quinolinic Acid Induced Depression-like Behavior and Memory Deficits in Wistar Rats
  96. Antimycobacterial Assessment and Microwave-assisted Synthesis of 2-aryl- 3-(4-methylphenylamino)thiazolidin-4-one Derivatives
  97. Synthesis, Characterization and Antimycobacterial Activity of Some Substituted Phenylpyridazinone Derivatives
  98. Discovery, Development, Inventions and Patent Review of Fexinidazole: The First All-Oral Therapy for Human African Trypanosomiasis
  99. Insights into the Protective Effects of Thymoquinone against Toxicities Induced by Chemotherapeutic Agents
  100. Synthesis and Antibacterial Evaluation of (E)-5-Arylidene-6-Methyl-4,5-Dihydropyridazin-3(2)-Thione Derivatives
  101. Interleukin-6 expression and its modulation by diacerein in a rat model of chronic stress induced cardiac dysfunction
  102. Evaluation of Antidiabetic Activity of Polyherbal Formulation “Vasant Kusumakar Ras” on Alloxan-induced and Dexamethasone-induced Diabetic Rats
  103. Anti-metastatic and Anticancer Potentials of Synthesized Chalcones in B16-F10 Melanoma Cells Induced Metastatic Lung Cancer in C57BL/6 Mice
  104. Development and Validation of LC-ESI-MS/MS Method for the Determination of Alfuzosin in Human Plasma
  105. Correction to: Optimization of Ultrasonic Extraction of Major Phenolic Components from Flowers of Ghav-Patta (Argyreia Speciosa Linn.) Via Response Surface Model
  106. Optimization of Ultrasonic Extraction of Major Phenolic Components from Flowers of Ghav-Patta (Argyreia Speciosa Linn.) Via Response Surface Model
  107. Identification of 3-((1-(Benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)pyrazine-2-carboxylic Acid as a Potential Inhibitor of Non-Nucleosidase Reverse Transcriptase Inhibitors through InSilico Ligand- and Structure-Based App...
  108. Evaluation of Haloxylon Persicum Leaves Ethanolic Extract for Phytochemical, Antioxidant, Anticancer, and Antimicrobial Properties
  109. Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention
  110. Correction to: Standardization and Wound-Healing Activity of Petroleum, Ethanolic and Aqueous Extracts of Ficus Benghalensis Leaves
  111. Standardization and Wound-Healing Activity of Petroleum, Ethanolic and Aqueous Extracts of Ficus Benghalensis Leaves
  112. Pharmacophore modeling, docking and the integrated use of a ligand- and structure-based virtual screening approach for novel DNA gyrase inhibitors: synthetic and biological evaluation studies
  113. Neuroprotective Effects of Co-Administration of Selegiline with Piracetam on Cognitive Impairment: Involvement of NR2B, NR1 and Bax Signaling Pathway
  114. An eco-friendly HPLC-UV method for the determination of risedronate in its bulk and tablet dosage form with application to content uniformity, dissolution and stability testing
  115. Pyrethroid-Induced Organ Toxicity and Anti-Oxidant-Supplemented Amelioration of Toxicity and Organ Damage: The Protective Roles of Ascorbic Acid and α-Tocopherol
  116. Neuroprotective Effect of Bambusa arundinaceae Leaves Extract on Learning and Memory Impairment in Mice: Impact on NR2B, NR1 and GAP Pathways
  117. Hepatoprotective activity of depsidone enriched Cladonia rangiferina extract against alcohol-induced hepatotoxicity targeting cytochrome P450 2E1 induced oxidative damage
  118. Evaluation of Antidepressant and Anxiolytic Activity of Solanum melongena L. Fruits Aqueous Extract via Monoaminergic and GABAergic Pathway
  119. Correction: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
  120. Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
  121. Oxidative free radicals scavenging activity (in vitro and in vivo assay) of standardized fractions from the seeds of Argyreia speciosa (Ghav-patta) a traditional Indian medicine
  122. Natural products and their active principles used in the treatment of neurodegenerative diseases: a review
  123. In vitro wound healing activity of 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde (HDNC) and other isolates of Aegle marmelos L.: Enhances keratinocytes motility via Wnt/β-catenin and RAS-ERK pathways
  124. Identification of Hydroxamic Acid Based Selective HDAC1 Inhibitors: Computer Aided Drug Design Studies
  125. Comparative study of subchronic toxicities of mosquito repellents (coils, mats and liquids) on vital organs in Swiss albino mice
  126. The Safety, Efficacy and Therapeutic Potential of Histone Deacetylase Inhibitors with Special Reference to Panobinostat in Gastrointestinal Tumors: A Review of Preclinical and Clinical Studies
  127. Anticonvulsant and neuroprotective effects of methanolic extract of Cinnamomum camphora leaves in rat brain
  128. Antitumor activity of extract and isolated compounds from Drechslera rostrata and Eurotium tonophilum
  129. Classification, causes, diagnosis and treatment of male infertility: a review
  130. Adaptogenic medicinal plants utilized for strengthening the power of resistance during chemotherapy–a review
  131. Therapeutic Potential of Polyherbal Formulation Against Experimentally Induced Insulin Resistant Myocardial Infarction in Rats
  132. Design, synthesis and evaluation of benzofuran-acetamide scaffold as potential anticonvulsant agent
  133. Phytochemical and Analytical Evaluation of Kachnal (Bauhinia racemosa Lam.) Bark
  134. Antidepressant Activity of Alcoholic Extract of the Fruits of Osmanthus fragrans Lour in Mice
  135. lawsonia inermis
  136. A comparative study of neuroprotective effect of angiotensin converting enzyme inhibitors against scopolamine-induced memory impairments in rats
  137. Evaluation of Cucurbita maxima Extract against Scopolamine- Induced Amnesia in Rats: Implication of Tumour Necrosis Factor Alpha
  138. Synthesis, Anticonvulsant and Neurotoxicity Evaluation of Some Newer N-(2-benzoylbenzofuran-3-yl)-3-(substituted)-propanamide Analogs
  139. 1,3,4-THIADIAZOLE AS ANTIMICROBIAL AGENT: A REVIEW
  140. HERBAL DRUGS IN MIRROR OF ANXIETY DISORDER -A REVIEW
  141. PHARMACOLOGICAL ACTIVITIES OF LAWSONIA INERMIS LINN.: A REVIEW