All Stories

  1. In silico Identification of Natural Compounds as Potential TrkA Inhibitors for Anticancer Drug Development

    Article • Iranian Journal of Pharmaceutical Research, May 2026, Kowsar Medical Institute

    Faizul Azam

  2. Open-Source Molecular Docking and AI-Augmented Structure-Based Drug Design: Current Workflows, Challenges, and Opportunities

    Article • International Journal of Molecular Sciences, April 2026, MDPI AG

    Faizul Azam

  3. Computational study of chalcone-cyanopyrimidine hybrids as LSD1 inhibitors: Assessing the influence of FAD on binding affinity and inhibition

    Article • Biochemistry and Biophysics Reports, December 2025, Elsevier

    Faizul Azam

  4. Cracking the Sulfur Code: Garlic Bioactive Molecules as Multi-Target Blueprints for Drug Discovery

    Article • Pharmaceuticals, November 2025, MDPI AG

    Faizul Azam

  5. Structural and Magneto-Optical Study on the Tetrahedrally Configured [CoCl2(1-allylimidazole)2] and Molecular Docking to Hypoxia-Inducible Factor-1α

    Article • Inorganics, October 2025, MDPI AG

    Faizul Azam, Sabrina Disch

  6. Thiazolidinedione‐Pyrimidine Hybrid as Potential Antidiabetic Agents and Their Cardioprotective Effect

    Article • Journal of Heterocyclic Chemistry, July 2025, Wiley

    Faizul Azam

  7. Targeting tubulin protein by novel 3,5-disubstituted-1,2,4-triazole analogues as anticancer agents: Design, synthesis, in-vitro, and in-silico studies

    Article • Journal of Molecular Structure, June 2025, Elsevier

    Dr Mohamed Jawed Ahsan, Faizul Azam

  8. Targeting Mitochondrial Drp1 Dynamics in Neurodegenerative Diseases: A Comprehensive Drug Design Approach Using AutoDock Vina‐GPU, DFT, and Molecular Dynamics Simulations

    Article • ChemistrySelect, May 2025, Wiley

    Faizul Azam

  9. Preclinical and Molecular Docking Insights into the Chemopreventive Role of Fenugreek Seed Extract in a Murine Model of Colorectal Cancer

    Article • Pharmaceuticals, March 2025, MDPI AG

    Faizul Azam

  10. Insights into the Therapeutic Targets and Molecular Mechanisms of Eruca sativa Against Colorectal Cancer: An Integrated Approach Combining Network Pharmacology, Molecular Docking and Dynamics Simulation

    Article • Pharmaceuticals, March 2025, MDPI AG

    Faizul Azam

  11. Monotherapy vs combination therapy evaluation of FDA-approved TKIs targeting PDGFR for the treatment of thyroid cancer

    Article • Journal of Biomolecular Structure and Dynamics, March 2025, Taylor & Francis

    Faizul Azam

  12. The Dynamic Role of Curcumin in Mitigating Human Illnesses: Recent Advances in Therapeutic Applications

    Article • Pharmaceuticals, December 2024, MDPI AG

    Faizul Azam

  13. Isolation, Characterization, and Anti‐Inflammatory Effects of β‐Sitosterol‐β‐D‐Glucoside from Hygrophila auriculata: Experimental Validation, Molecular Docking, and Molecular Dynamics Simulations

    Article • Chemistry & Biodiversity, November 2024, Wiley

    Faizul Azam

  14. The Dynamic Role of Curcumin in Mitigating Human Illnesses: Recent Advances in Therapeutic Applications

    Article • September 2024, MDPI AG

    Faizul Azam

  15. Adsorption of methotrexate on hyaluronic acid: A comparative DFT and molecular dynamics simulation insights

    Article • Chemical Physics Impact, June 2024, Elsevier

    Faizul Azam

  16. Solvent-free Synthesis, Anticancer Activity and In-Silico Studies of 7-Hydroxy-4-methylquinolin-2(1H)-one Analogues

    Article • Journal of Molecular Structure, May 2024, Elsevier

    Dr Mohamed Jawed Ahsan, Faizul Azam

  17. Deciphering Campylobacter jejuni DsbA1 protein dynamics in the presence of anti-virulent compounds: a multi-pronged computer-aided approach

    Article • Journal of Biomolecular Structure and Dynamics, January 2024, Taylor & Francis

    Faizul Azam

  18. Eucalyptus-derived essential oils alleviate microbes and modulate inflammation by suppressing superoxide and elastase release

    Article • Frontiers in Pharmacology, November 2023, Frontiers

    Faizul Azam

  19. Synthesis, molecular docking, and in vivo antidiabetic evaluation of new benzylidene-2,4-thiazolidinediones as partial PPAR-γ agonists

    Article • Scientific Reports, November 2023, Springer Science + Business Media

    Faizul Azam

  20. Identification of potential inhibitors of HER2 targeting breast cancer—a structure-based drug design approach

    Article • Journal of Biomolecular Structure and Dynamics, August 2023, Taylor & Francis

    Faizul Azam

  21. The role of Aedes aegypti in inducing/aggravating IgE-mediated allergic airway disease: extensive computational studies for identification of allergenic proteins

    Article • Journal of Biomolecular Structure and Dynamics, May 2023, Taylor & Francis

    Faizul Azam

  22. Effectiveness of estrogen and its derivatives over dexamethasone in the treatment of COVID-19

    Article • Journal of Biomolecular Structure and Dynamics, May 2023, Taylor & Francis

    Faizul Azam

  23. Development and Evaluation of Novel Encapsulated Isoeugenol-Liposomal Gel Carrier System for Methicillin-Resistant Staphylococcus aureus

    Article • Gels, March 2023, MDPI AG

    Faizul Azam, Dr MEHNAZ KAMAL

  24. The Enhanced Affinity of WRKY Reinforces Drought Tolerance in Solanum lycopersicum L.: An Innovative Bioinformatics Study

    Article • Plants, February 2023, MDPI AG

    Faizul Azam

  25. Formulation, In Vitro and In Silico Evaluations of Anise (Pimpinella anisum L.) Essential Oil Emulgel with Improved Antimicrobial Effects

    Article • Gels, January 2023, MDPI AG

    Faizul Azam, Dr MEHNAZ KAMAL

  26. Dynamic and thermodynamic impact of L94A, W100A, and W100L mutations on the D2 dopamine receptor bound to risperidone

    Article • November 2022, Springer Science + Business Media

    Faizul Azam

  27. Synthesis, DFT Analyses, Antiproliferative Activity, and Molecular Docking Studies of Curcumin Analogues

    Article • Plants, October 2022, MDPI AG

    Dr Mohamed Jawed Ahsan, Faizul Azam

  28. The Structural, Biological, and In-Silico Profiling of Novel Capryloyl Tetra-Glucoside and Aliphatic Ester Constituents from the Abutilon indicum Offers New Perspectives on the Treatment of Pain and Inflammation

    Article • Plants, September 2022, MDPI AG

    Faizul Azam

  29. Microsecond MD Simulations to Explore the Structural and Energetic Differences between the Human RXRα-PPARγ vs. RXRα-PPARγ-DNA

    Article • Molecules, September 2022, MDPI AG

    Faizul Azam

  30. A simple validated HPTLC method for the analysis of flavonoids and molecular docking studies of novel tri-terpenoid glycoside isolated from Carya illinoinensis bark with potential anti-inflammatory and antinociceptive activities

    Article • South African Journal of Botany, July 2022, Elsevier

    Faizul Azam

  31. Structural and energetic differences between the human RXRα–PPARγ heterodimer with and without DNA binding

    Article • June 2022, Springer Science + Business Media

    Faizul Azam

  32. Synthesis and characterization of liquid crystalline poly(ether-ketone)s containing 1-benzyl-4-piperidone moiety as a pendent group

    Article • Journal of Molecular Structure, June 2022, Elsevier

    Faizul Azam

  33. In silico and in vitro studies on the inhibition of laccase activity by Ellagic acid: Implications in drug designing for the treatment of Cryptococcal infections

    Article • International Journal of Biological Macromolecules, June 2022, Elsevier

    Faizul Azam

  34. Structural, functional, molecular, and biological evaluation of novel triterpenoids isolated from Helichrysum stoechas (L.) Moench. Collected from Mediterranean Sea bank: Misurata- Libya

    Article • Arabian Journal of Chemistry, June 2022, Scientific Scholar

    Faizul Azam

  35. New Paradigms of Old Psychedelics in Schizophrenia

    Article • Pharmaceuticals, May 2022, MDPI AG

    Faizul Azam

  36. Toward the Discovery of a Novel Class of Leads for High Altitude Disorders by Virtual Screening and Molecular Dynamics Approaches Targeting Carbonic Anhydrase

    Article • International Journal of Molecular Sciences, May 2022, MDPI AG

    Dr Mohamed Jawed Ahsan, Faizul Azam

  37. Experimental and Theoretical Insights on Chemopreventive Effect of the Liposomal Thymoquinone Against Benzo[a]pyrene-Induced Lung Cancer in Swiss Albino Mice

    Article • Journal of Inflammation Research, April 2022, Taylor & Francis

    Faizul Azam

  38. Lipid-Based Nanoparticle Formulation of Diallyl Trisulfide Chemosensitizes the Growth Inhibitory Activity of Doxorubicin in Colorectal Cancer Model: A Novel In Vitro, In Vivo and In Silico Analysis

    Article • Molecules, March 2022, MDPI AG

    Faizul Azam

  39. An Insight into the Structural Requirements and Pharmacophore Identification of Carbonic Anhydrase Inhibitors to Combat Oxidative Stress at High Altitudes: An In-Silico Approach

    Article • Current Issues in Molecular Biology, February 2022, MDPI AG

    Dr Mohamed Jawed Ahsan, Faizul Azam

  40. The Effect of Liposomal Diallyl Disulfide and Oxaliplatin on Proliferation of Colorectal Cancer Cells: In Vitro and In Silico Analysis

    Article • Pharmaceutics, January 2022, MDPI AG

    Faizul Azam

  41. Safety, Stability, and Therapeutic Efficacy of Long-Circulating TQ-Incorporated Liposomes: Implication in the Treatment of Lung Cancer

    Article • Pharmaceutics, January 2022, MDPI AG

    Faizul Azam

  42. Green Synthesis of Oxoquinoline-1(2H)-Carboxamide as Antiproliferative and Antioxidant Agents: An Experimental and In-Silico Approach to High Altitude Related Disorders

    Article • Molecules, January 2022, MDPI AG

    Dr Mohamed Jawed Ahsan, Faizul Azam

  43. Synthesis and biological studies of oxoquinolines: Experimental and theoretical investigations

    Article • Journal of Molecular Structure, January 2022, Elsevier

    Faizul Azam, Dr Mohamed Jawed Ahsan

  44. Dynamic and thermodynamic impact of L94A, W100A, and W100L mutations on the D2 dopamine receptor bound to risperidone

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Faizul Azam

  45. Targeting SARS-CoV-2 main protease by teicoplanin: A mechanistic insight by docking, MM/GBSA and molecular dynamics simulation

    Article • Journal of Molecular Structure, December 2021, Elsevier

    Faizul Azam

  46. Current Status of Novel Pyridine Fused Derivatives as Anticancer Agents: An Insight into Future Perspectives and Structure Activity Relationship (SAR)

    Article • Current Topics in Medicinal Chemistry, October 2021, Bentham Science Publishers

    Dr. Asif Husain, Ajay Manaithiya, Ozair Alam, Faizul Azam, Vrinda Sharma

  47. Host Cell and SARS-CoV-2-Associated Molecular Structures and Factors as Potential Therapeutic Targets

    Article • Cells, September 2021, MDPI AG

    Faizul Azam

  48. An insight into the implications of estrogen deficiency and transforming growth factor β in antiepileptic drugs-induced bone loss

    Article • European Journal of Pharmacology, September 2021, Elsevier

    Faizul Azam

  49. In Vitro and In Silico Approaches for the Antileishmanial Activity Evaluations of Actinomycins Isolated from Novel Streptomyces smyrnaeus Strain UKAQ_23

    Article • Antibiotics, July 2021, MDPI AG

    Faizul Azam

  50. Elucidation of Teicoplanin Interactions with Drug Targets Related to COVID-19

    Article • Antibiotics, July 2021, MDPI AG

    Faizul Azam

  51. Isolation, characterization, anti-MRSA evaluation, and in-silico multi-target anti-microbial validations of actinomycin X2 and actinomycin D produced by novel Streptomyces smyrnaeus UKAQ_23

    Article • Scientific Reports, July 2021, Springer Science + Business Media

    Faizul Azam

  52. On Ve-Degree and Ev-Degree Topological Properties of Hyaluronic Acid‐Anticancer Drug Conjugates with QSPR

    Article • Journal of Chemistry, July 2021, Hindawi Publishing Corporation

    Faizul Azam

  53. Effect of thymoquinone on high fat diet and STZ‐induced experimental type 2 diabetes: A mechanistic insight by in vivo and in silico studies

    Article • Journal of Food Biochemistry, June 2021, Wiley

    Faizul Azam

  54. Liposomal Ellagic Acid Alleviates Cyclophosphamide-Induced Toxicity and Eliminates the Systemic Cryptococcus neoformans Infection in Leukopenic Mice

    Article • Pharmaceutics, June 2021, MDPI AG

    Faizul Azam

  55. Inclusion complex of clausenidin with hydroxypropyl-β-cyclodextrin: Improved physicochemical properties and anti-colon cancer activity

    Article • Saudi Pharmaceutical Journal, March 2021, Elsevier

    Faizul Azam

  56. Topological indices andQSPR/QSARanalysis of some antiviral drugs being investigated for the treatment ofCOVID‐19 patients

    Article • International Journal of Quantum Chemistry, December 2020, Wiley

    Parvez Ali, Faizul Azam

  57. Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity – Probable role of NLRP3 inflammasome and caspase-1

    Article • Experimental Neurology, December 2020, Elsevier

    Faizul Azam

  58. Anti-inflammatory, analgesic and molecular docking studies of Lanostanoic acid 3-O-α-D-glycopyranoside isolated from Helichrysum stoechas

    Article • Arabian Journal of Chemistry, December 2020, Scientific Scholar

    Faizul Azam

  59. An in-silico analysis of ivermectin interaction with potential SARS-CoV-2 targets and host nuclear importin α

    Article • Journal of Biomolecular Structure and Dynamics, November 2020, Taylor & Francis

    Faizul Azam

  60. Design and synthesis of pyrazole–pyrazoline hybrids as cancer‐associated selective COX‐2 inhibitors

    Article • Archiv der Pharmazie, October 2020, Wiley

    Faizul Azam

  61. Degree-based topological indices and polynomials of hyaluronic acid-curcumin conjugates

    Article • Saudi Pharmaceutical Journal, September 2020, Elsevier

    Faizul Azam

  62. Targeting SARS-CoV-2 Main Protease by Teicoplanin: A Mechanistic Insight by in Silico Studies

    Article • June 2020, American Chemical Society (ACS)

    Faizul Azam

  63. Development and validation of a novel UPLC-MS/MS method for quantification of delafloxacin in plasma and aqueous humour for pharmacokinetic analyses

    Article • Journal of Chromatography B, February 2020, Elsevier

    Faizul Azam

  64. Breaking Down the Barriers to a Natural Antiviral Agent: Antiviral Activity and Molecular Docking of Erythrina speciosa Extract, Fractions, and the Major Compound

    Article • Chemistry & Biodiversity, January 2020, Wiley

    Faizul Azam

  65. Rutin as promising drug for the treatment of Parkinson’s disease: an assessment of MAO-B inhibitory potential by docking, molecular dynamics and DFT studies

    Article • Molecular Simulation, September 2019, Taylor & Francis

    Dr. Danish Mahmood, Md Jamir Anwar, Faizul Azam

  66. Zerumbone Induces Apoptosis in Breast Cancer Cells by Targeting αvβ3 Integrin upon Co-Administration with TP5-iRGD Peptide

    Article • Molecules, July 2019, MDPI AG

    Dr. Mohammed Abdullah Alshawsh, Faizul Azam

  67. Zerumbone binding to estrogen receptors: an in-silico investigation

    Article • Journal of Receptors and Signal Transduction, July 2018, Taylor & Francis

    Mohammad Halim, Eltayeb Eid, Faizul Azam

  68. NSAIDs as potential treatment option for preventing amyloid β toxicity in Alzheimer’s disease: an investigation by docking, molecular dynamics, and DFT studies

    Article • Journal of Biomolecular Structure and Dynamics, June 2017, Taylor & Francis

    Abdullah R. Abulifa, nada alabdullah, Faizul Azam

  69. Ester Prodrugs of Ketoprofen: Synthesis, In Vitro Stability, In Vivo Biological Evaluation and In Silico Comparative Docking Studies Against COX-1 and COX-2

    Article • Current Drug Discovery Technologies, March 2016, Bentham Science Publishers

    Dr Musa Ahmed, Faizul Azam

  70. Molecular interaction studies of green tea catechins as multitarget drug candidates for the treatment of Parkinson’s disease: computational and structural insights

    Article • Network Computation in Neural Systems, October 2015, Taylor & Francis

    Faizul Azam

  71. Anti-endotoxin effects of terpenoids fraction fromHygrophila auriculatain lipopolysaccharide-induced septic shock in rats

    Article • Pharmaceutical Biology, October 2015, Taylor & Francis

    Faizul Azam

  72. Ginger with Alzheimer’s disease

    Article • Drug Design Development and Therapy, October 2014, Taylor & Francis

    Abdullah R. Abulifa, Abdualrahman moftah Amer, Faizul Azam

  73. Synthesis and characterization of polyesters based on diethylketone moiety

    Article • Chinese Journal of Polymer Science, September 2014, Springer Science + Business Media

    Faizul Azam

  74. In-silico investigation of the structural requirements for the AMPA receptor antagonism by quinoxaline derivatives

    Article • Bioinformation, October 2013, Biomedical Informatics

    Faizul Azam

  75. Oxasetin from Lophiostoma sp. of the Baltic Sea: Identification, in silico Binding Mode Prediction and Antibacterial Evaluation against Fish Pathogenic Bacteria

    Article • Natural Product Communications, September 2013, SAGE Publications

    Faizul Azam

  76. Synthesis, characterization and biological activity of polyketones

    Article • Chinese Journal of Polymer Science, December 2012, Springer Science + Business Media

    Faizul Azam

  77. Structure-Based Design, Synthesis and Molecular Modeling Studies of Thiazolyl Urea Derivatives as Novel Anti-Parkinsonian Agents

    Article • Medicinal Chemistry, September 2012, Bentham Science Publishers

    Faizul Azam, Neelaveni Thangavel

  78. Molecular Docking and Prediction of Pharmacokinetic Properties of Dual Mechanism Drugs that Block MAO-B and Adenosine A2A Receptors for the Treatment of Parkinson's Disease

    Article • Journal of Young Pharmacists, July 2012, EManuscript Services

    Faizul Azam

  79. Targeting Oxidative Stress Component in the Therapeutics of Epilepsy

    Article • Current Topics in Medicinal Chemistry, April 2012, Bentham Science Publishers

    Faizul Azam, Neelaveni Thangavel

  80. Structure-based design, synthesis, molecular docking, and biological activities of 2-(3-benzoylphenyl) propanoic acid derivatives as dual mechanism drugs

    Article • Journal of Pharmacy and Bioallied Sciences, January 2012, Medknow

    Faizul Azam

  81. Structure-based design, synthesis, and molecular modeling studies of 1-(benzo[d]thiazol-2-yl)-3-(substituted aryl)urea derivatives as novel anti-Parkinsonian agents

    Article • Medicinal Chemistry Research, September 2011, Springer Science + Business Media

    Faizul Azam, Neelaveni Thangavel

  82. Molecular docking studies of 1-(substituted phenyl)-3-(naphtha [1, 2-d] thiazol-2-yl) urea/thiourea derivatives with human adenosine A2A receptor

    Article • Bioinformation, July 2011, Biomedical Informatics

    Faizul Azam

  83. Synthesis of quinoline attached-furan-2(3H)-ones having anti-inflammatory and antibacterial properties with reduced gastro-intestinal toxicity and lipid peroxidation

    Article • Journal of the Serbian Chemical Society, January 2011, National Library of Serbia

    Faizul Azam, Dr. Asif Husain

  84. Combating oxidative stress in epilepsy: Design, synthesis, quantum chemical studies and anticonvulsant evaluation of 1-(substituted benzylidene/ethylidene)-4-(naphthalen-1-yl)semicarbazides

    Article • European Journal of Medicinal Chemistry, July 2010, Elsevier

    Faizul Azam

  85. Design, synthesis and anti-Parkinsonian evaluation of 3-alkyl/aryl-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thiones against neuroleptic-induced catalepsy and oxidative stress in mice

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, April 2010, Taylor & Francis

    Faizul Azam

  86. Synthesis and characterization of new unsaturated polyesters containing cyclopentapyrazoline moiety in the main chain

    Article • Journal of Applied Polymer Science, March 2010, Wiley

    Faizul Azam

  87. ChemInform Abstract: Synthesis of Some Urea and Thiourea Derivatives of 3‐Phenyl/Ethyl‐2‐thioxo‐2,3‐dihydrothiazolo[4,5‐d]pyrimidine and Their Antagonistic Effects on Haloperidol‐Induced Catalepsy and Oxidative Stress in Mice.

    Article • ChemInform, December 2009, Wiley

    Faizul Azam

  88. Synthesis of some urea and thiourea derivatives of 3-phenyl/ethyl-2-thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidine and their antagonistic effects on haloperidol-induced catalepsy and oxidative stress in mice

    Article • European Journal of Medicinal Chemistry, October 2009, Elsevier

    Faizul Azam

  89. Neuroprotective effect of naphtha[1,2-d]thiazol-2-amine in an animal model of Parkinson's disease

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, June 2009, Taylor & Francis

    Faizul Azam

  90. Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl)semicarbazides as potential anticonvulsants

    Article • European Journal of Medicinal Chemistry, January 2009, Elsevier

    Faizul Azam

  91. Synthesis of some urea and thiourea derivatives of naphtha[1,2-d]thiazol-2-amine as anti-Parkinsonian agents that cause neuroprotection against haloperidol-induced oxidative stress in mice

    Article • Medicinal Chemistry Research, November 2008, Springer Science + Business Media

    Faizul Azam

  92. Synthesis of Schiff bases of naphtha[1,2-d]thiazol-2-amine and metal complexes of 2-(2′-hydroxy)benzylideneaminonaphthothiazole as potential antimicrobial agents

    Article • Journal of Zhejiang University SCIENCE B, May 2007, Journal of Zhejiang University SCIENCE

    Faizul Azam