All Stories

  1. Antiproliferative effect of ketogenic diet on hormone independent mammary gland carcinoma via harnessing glucose metabolism: In-vitro and In-vivo investigations
  2. Immune-related adverse events in immunotherapy: Challenges in diagnosis, monitoring, and management
  3. Repurposing brucine as a chemopreventive agent in mammary gland carcinoma: Regulating lactate transport through MCT-4
  4. Small interfering RNA: From designing to therapeutic in cancer
  5. Molecular Mechanisms and Therapeutic Targeting of Heat Shock Proteins (HSPs) in Cardiovascular Disorders
  6. Exploring the Impact of Polysaccharide‐Based Nanoemulsions in Drug Delivery
  7. Emerging Therapeutic Agents and Nanotechnology-Driven Innovations in Psoriasis Management
  8. Advancing siRNA Therapeutics targeting MCT-4: A Multifaceted approach integrating Arithmetical Designing, Screening, and molecular dynamics validation
  9. Simultaneous determination of theobromine (THEOB), theophylline (THEOP) and caffeine (CAF) in commercially available food products using UPLC technique
  10. Unlocking the Molecular Targets in Non-Small-Cell Lung Cancer and a Nanomedicine-Based Remedy
  11. Design, synthesis, molecular dynamics and gene silencing studies of novel therapeutic HIF-1α siRNAs in hypoxic cancer cells
  12. A novel quinazoline derivative exhibits potent anticancer cytotoxicity via apoptosis and inhibition of angiogenesis in DMBA‐induced mammary gland carcinoma
  13. Antiproliferative, apoptotic and anti-inflammatory potential of 5H-benzo[h]thiazolo[2,3-b]quinazoline analogues: Novel series of anticancer compounds
  14. Antiproliferative effect of indeno[1,2-d]thiazolo[3,2-a]pyrimidine analogues on IL-6 mediated STAT3 and role of the apoptotic pathway in albino Wistar rats of ethyl carbamate-induced lung carcinoma: In-silico, In-vitro, and In-vivo study
  15. Formulation of Phytosomes Containing Rubia cordifolia Extract for Neuropathic Pain: In Vitro and In Vivo Evaluation
  16. Novel Quinazoline Derivative Activates FIH-1 in MCF-7 Cells and 7, 12-Dimethylbenz[a]-Anthracene Induced Mammary Gland Carcinoma in Albino Rats
  17. Novel carbamodithioate regulates cellular hypoxia through chemical activation of prolyl hydroxylase‐2 for breast cancer chemoprevention
  18. Predictive insights into plant-based compounds as fibroblast growth factor receptor 1 inhibitors: a combined molecular docking and dynamics simulation study
  19. Exploring progress in iron supplement formulation approaches for treating iron deficiency anemia through bibliometric and thematic analysis
  20. Novel furan chalcone modulates PHD‐2 induction to impart antineoplastic effect in mammary gland carcinoma
  21. An Insight on Microfluidic Organ-on-a-Chip Models for PM2.5-Induced Pulmonary Complications
  22. Emerging Trends of Nanomedicines in the Management of Prostate Cancer: Perspectives and Potential Applications
  23. Investigating the Potential Impact of Air Pollution on Alzheimer’s Disease and the Utility of Multidimensional Imaging for Early Detection
  24. Calcium Channel Inhibitory Effect of Marjoram (Origanum majorana L.): Its Medicinal Use in Diarrhea and Gut Hyperactivity
  25. Comparison of various sample preparation methods for benzodiazepines in terms of the principles of white analytical chemistry
  26. Pharmacological Basis for the Antidiarrheal and Antispasmodic Effects of Cuminaldehyde in Experimental Animals: In Silico, Ex Vivo and In Vivo Studies
  27. Optimization of novel method for isolation of high purity food grade α-linolenic acid from Linum usitatissimum seeds
  28. A pharmacological review on SIRT 1 and SIRT 2 proteins, activators, and inhibitors: Call for further research
  29. Postpartum depression: aetiology, pathogenesis and the role of nutrients and dietary supplements in prevention and management
  30. Potential therapeutic effect of Carica papaya leaves extract on immune response, biochemical and hematological mechanisms on cecal ligation and puncture model of sepsis in rats: an in vivo study
  31. Cell Signaling Pathways in Cancer
  32. An Overview of Nanoemulgels for Bioavailability Enhancement in Inflammatory Conditions via Topical Delivery
  33. Plant-Derived Bioactive Compounds in the Management of Neurodegenerative Disorders: Challenges, Future Directions and Molecular Mechanisms Involved in Neuroprotection
  34. NF-κB mediated regulation of tumor cell proliferation in hypoxic microenvironment
  35. Molecular Docking of Bacterial Protein Modulators and Pharmacotherapeutics of Carica papaya Leaves as a Promising Therapy for Sepsis: Synchronising In Silico and In Vitro Studies
  36. The Detailed Pharmacodynamics of the Gut Relaxant Effect and GC-MS Analysis of the Grewia tenax Fruit Extract: In Vivo and Ex Vivo Approach
  37. Investigation of Trends in the Research on Transferrin Receptor-Mediated Drug Delivery via a Bibliometric and Thematic Analysis
  38. Wound Healing Potential of Commiphora gileadensis Stems Essential Oil and Chloroform Extract
  39. Degradation of Xenobiotic Pollutants: An Environmentally Sustainable Approach
  40. Correction: Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling
  41. Crisaborole Loaded Nanoemulsion Based Chitosan Gel: Formulation, Physicochemical Characterization and Wound Healing Studies
  42. Dual Inhibition of Phosphodiesterase and Ca++ Channels Explains the Medicinal Use of Balanites aegyptiaca (L.) in Hyperactive Gut Disorders
  43. GC–MS Analysis and In Vivo and Ex Vivo Antidiarrheal and Antispasmodic Effects of the Methanolic Extract of Acacia nilotica
  44. Dysregulation of multiple signaling pathways: A possible cause of cerebral palsy
  45. In Silico and Ex Vivo Studies on the Spasmolytic Activities of Fenchone Using Isolated Guinea Pig Trachea
  46. Myrica salicifolia Hochst. ex A. Rich. suppress acetic acid-induced ulcerative colitis in rats by reducing TNF-alpha and interleukin-6, oxidative stress parameters and improving mucosal protection
  47. Analgesic, antipyretic, anti-inflammatory, and hepatoprotective activities of Pulicaria crispa (Forssk.) Oliv. (Asteraceae)
  48. Development of Sustained Release Baricitinib Loaded Lipid-Polymer Hybrid Nanoparticles with Improved Oral Bioavailability
  49. Repurposing Combination Therapy of Voacamine With Vincristine for Downregulation of Hypoxia-Inducible Factor-1α/Fatty Acid Synthase Co-axis and Prolyl Hydroxylase-2 Activation in ER+ Mammary Neoplasia
  50. In vivo wound-healing and antioxidant activity of aqueous extract of Roylea elegans leaves against physically induced burn model in Wistar albino rats
  51. Experimental Rodent Models of Vascular Dementia: A Systematic Review
  52. Modulation of Host Immune Response Is an Alternative Strategy to Combat SARS-CoV-2 Pathogenesis
  53. Polyunsaturated Fatty Acids Mediated Regulation of Membrane Biochemistry and Tumor Cell Membrane Integrity
  54. Effect of Voacamine upon inhibition of hypoxia induced fatty acid synthesis in a rat model of methyln-nitrosourea induced mammary gland carcinoma
  55. Effects of Essential Oils of Elettaria cardamomum Grown in India and Guatemala on Gram-Negative Bacteria and Gastrointestinal Disorders
  56. Improving the Solubilization and Bioavailability of Arbidol Hydrochloride by the Preparation of Binary and Ternary β-Cyclodextrin Complexes with Poloxamer 188
  57. Dysregulation of Multiple Signaling Neurodevelopmental Pathways during Embryogenesis: A Possible Cause of Autism Spectrum Disorder
  58. Possible Tracheal Relaxant and Antimicrobial Effects of the Essential Oil of Ethiopian Thyme Species (Thymus serrulatus Hochst. ex Benth.): A Multiple Mechanistic Approach
  59. Evaluation of antidiabetic and hypolipidemic activity of Barleria cristata Linn. leaves in alloxan-induced diabetic rats
  60. Red Yeast Rice Mitigates High-Fat Diet Induced-Obesity Related Vascular Dysfunction in Wistar Albino Rats
  61. Role of Oxidative Stress and Inflammatory Cytokines (TNF-α and IL-6) in Acetic Acid-Induced Ulcerative Colitis in Rats: Ameliorated by Otostegia fruticosa
  62. Effects of Essential oils of Elettaria cardamomum Grown in India and Guatemala on Pseudomonas aeruginosa, Escherichia coli, and Gastrointestinal Disorders
  63. Preparation of spray dried amorphous solid dispersion of diosmin in soluplus with improved hepato-renoprotective activity: In vitro anti-oxidant and in-vivo safety studies
  64. Assessment of Antidiarrheal, Antispasmodic and Antimicrobial Activities of Methanolic Seeds Extract of Peganum harmala L. (Nitrariaceae)
  65. Novel β-Coronavirus (SARS-CoV-2): Current and future aspects of pharmacological treatments
  66. Teratogenic Effect of Chlorpyrifos and Glyphosate on Pregnant Rats: Biochemical and Morphological Evaluations
  67. Eluxadoline Loaded Solid Lipid Nanoparticles for Improved Colon Targeting in Rat Model of Ulcerative Colitis
  68. Pyrethroid-Induced Organ Toxicity and Anti-Oxidant-Supplemented Amelioration of Toxicity and Organ Damage: The Protective Roles of Ascorbic Acid and α-Tocopherol
  69. Cerebral palsy: Aetiology, pathophysiology and therapeutic interventions
  70. Role of inflammatory markers in corona virus disease (COVID-19) patients: A review
  71. Brucine Prevents DMH Induced Colon Carcinogenesis in Wistar Rats
  72. Roflumilast counteracts DMH-induced preneoplastic colon damage in albino Wistar rats
  73. Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca2+-channel
  74. THE POTENTIAL CARDIOPROTECTIVE EFFECT OF MATRICARIA CHAMOMILLA EXTRACT AGAINST DIABETES-INDUCED OXIDATIVE STRESS IN RATS
  75. Evaluation of bronchodialatory and antimicrobial activities of Otostegia fruticosa: A multi-mechanistic approach
  76. Short communication: Evaluation of α-linolenic acid–based intramammary nanosuspension for treatment of subclinical mastitis
  77. In Silico, Ex Vivo and In Vivo Studies of Roflumilast as a Potential Antidiarrheal and Antispasmodic agent: Inhibition of the PDE-4 Enzyme and Voltage-gated Ca++ ion Channels
  78. Cadmium-induced Hepatotoxicity and Oxidative Stress in Rats: Protection by Roflumilast via NF-κ B and HO-1 Pathway
  79. Sustained release and enhanced oral bioavailability of rivaroxaban by PLGA nanoparticles with no food effect
  80. Formulation, characterization, in vitro and in vivo evaluations of self-nanoemulsifying drug delivery system of luteolin
  81. Corrigendum to “Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways” [Pharmacol. Rep. 70 (2018) 993–1000]
  82. Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling
  83. Alpha-linolenic acid based nano-suspension protect against lipopolysaccharides induced mastitis by inhibiting NFκBp65, HIF-1α, and mitochondria-mediated apoptotic pathway in albino Wistar rats
  84. Protective role of Roflumilast against cadmium-induced cardiotoxicity through inhibition of oxidative stress and NF-κB signaling in rats
  85. PHD-2 activation: a novel strategy to control HIF-1α and mitochondrial stress to modulate mammary gland pathophysiology in ER+ subtype
  86. Transcutaneous Vagus Nerve Stimulation Regulates the Cholinergic Anti-inflammatory Pathway to Counteract 1, 2-Dimethylhydrazine Induced Colon Carcinogenesis in Albino wistar Rats
  87. Activation of prolyl hydroxylase‐2 for stabilization of mitochondrial stress along with simultaneous downregulation of HIF‐1α/FASN in ER + breast cancer subtype
  88. Roflumilast, a phosphodiesterase 4 inhibitor, attenuates cadmium-induced renal toxicity via modulation of NF-κB activation and induction of NQO1 in rats
  89. Comparative study of subchronic toxicities of mosquito repellents (coils, mats and liquids) on vital organs in Swiss albino mice
  90. Prolyl hydroxylase 2: a promising target to inhibit hypoxia-induced cellular metabolism in cancer cells
  91. Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways
  92. Protective Role of Aerial Parts of Silene villosa Alcoholic Extract Against CCl4-Induced Cardiac and Renal Toxicity in Rats
  93. Spectroscopic and molecular modeling studies of binding interaction between bovine serum albumin and roflumilast
  94. Effects of phenidone (DuCLOX-2/5 inhibitor) against N -methyl- N -nitrosourea induced mammary gland carcinoma in albino rats
  95. Antidiabetic activity of mefloquine via GLP-1 receptor modulation against STZ–NA-induced diabetes in albino wistar rats
  96. Revisiting the systemic lipopolysaccharide mediated neuroinflammation: Appraising the effect of l -cysteine mediated hydrogen sulphide on it
  97. DuCLOX-2/5 Inhibition Attenuates Inflammatory Response and Induces Mitochondrial Apoptosis for Mammary Gland Chemoprevention
  98. Evaluation of the diuretic potentials of naringenin in hypercholesterolemic rats
  99. Modulation of oxidative stress response by flaxseed oil: Role of lipid peroxidation and underlying mechanisms
  100. GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinoma
  101. Effect of early natal supplementation of paracetamol on attenuation of exotoxin/endotoxin induced pyrexia and precipitation of autistic like features in albino rats
  102. Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention
  103. Comparative efficacy of alpha-linolenic acid and gamma-linolenic acid to attenuate valproic acid-induced autism-like features
  104. Protective effects of two Astragalus species on ulcerative colitis in rats
  105. Development and evaluation of PLGA polymer based nanoparticles of quercetin
  106. Evaluation of the diuretic and urinary electrolyte effects of methanolic extract of Peganum harmala L. in Wistar albino rats
  107. Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats
  108. α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats
  109. Experimental Models for Autism Spectrum Disorder Follow-Up for the Validity
  110. DuCLOX-2/5 inhibition: a promising target for cancer chemoprevention
  111. Redefining the role of peripheral LPS as a neuroinflammatory agent and evaluating the role of hydrogen sulphide through metformin intervention
  112. Effect of β-sitosterol against methyl nitrosourea-induced mammary gland carcinoma in albino rats
  113. Palonosetron attenuates 1,2-dimethyl hydrazine induced preneoplastic colon damage through downregulating acetylcholinesterase expression and up-regulating synaptic acetylcholine concentration
  114. Enhanced oral bioavailability of insulin-loaded solid lipid nanoparticles: pharmacokinetic bioavailability of insulin-loaded solid lipid nanoparticles in diabetic rats
  115. Isoeugenol accelerates wound healing by attenuating pro-inflammatory markers and chemokine expression in diabetic mice
  116. Ameliorative effect of methanol extract ofRumex vesicariuson CCl4-induced liver damage in Wistar albino rats
  117. Synthesis, analgesic, anti-inflammatory and anti-ulcerogenic activities of certain novel Schiff’s bases as fenamate isosteres
  118. Antioxidant potential of Rumex vesicarius L.: in vitro approach
  119. Oral Dose of Citrus Peel Extracts Promotes Wound Repair in Diabetic Rats
  120. Inclusion Complex of Solid State Aspirin with Fulvic Acid: Dissolution, Permeability, Stability and Preliminary Pharmacological Studies
  121. Effect of ethanol extract ofEmbelia ribesfruits on cardiac changes in rats subjected to ischemic reperfusion injury
  122. Ameliorative effect of an ethanol extract ofEmbelia ribesfruits on isoproterenol-induced cardiotoxicity in diabetic rats
  123. Effect of folic acid on hematological changes in methionine-induced hyperhomocysteinemia in rats
  124. Effect of Rosuvastatin on Methionine-Induced Hyperhomocysteinaemia and Haematological Changes in Rats
  125. Beneficial effect of Embelia ribes ethanolic extract on blood pressure and glycosylated hemoglobin in streptozotocin-induced diabetes in rats
  126. Evaluation of antioxidant and neuroprotective effect of ethanolic extract of Embelia ribes Burm in focal cerebral ischemia/reperfusion-induced oxidative stress in rats
  127. THE CARDIOPROTECTIVE EFFECT OF AQUEOUS EXTRACT OF EMBELIA RIBES BURM ON ISOPROTERENOL- INDUCED MYOCARDIAL INFARCTION IN ALBINO RATS
  128. REDUCTION OF SERUM HOMOCYSTEINE AND LIPID LEVELS BY AQUEOUS EMBELIA RIBES BURM EXTRACT IN METHIONINE-INDUCED HYPERHOMOCYSTEINEMIA IN RATS
  129. Protective effect of aqueous extract of Embelia ribes Burm fruits in middle cerebral artery occlusion-induced focal cerebral ischemia in rats
  130. Effect of an Ethanol Extract ofEmbelia ribesFruits on Isoproterenol-Induced Myocardial Infarction in Albino Rats
  131. The effect of aqueous extract ofEmbelia ribesBurm on serum homocysteine, lipids and oxidative enzymes in methionine induced hyperhomocysteinemia
  132. Antihyperhomocysteinemic Activity of an Ethanol Extract fromEmbelia ribes. in Albino Rats
  133. Protective role of curcumin in myocardial oxidative damage induced by isoproterenol in rats