All Stories

  1. Synthesis and biological evaluation of N-acyl diaryl pyrimidines (NDAPYs) as novel reverse transcriptase inhibitors
  2. Exploration of Glitazone/Thiazolidinedione Derivatives: Molecular Design and Therapeutic Potential
  3. Targeting EGFR by newer 4,6-Bis(( E )-4-hydroxy-3-methoxystyryl)-1-(aryl)pyrimidin-2(1 H )-one analogues as antiproliferative agents: eco-friendly chemical modification, in-vi...
  4. Advances in the Synthesis and Therapeutic Exploration of Pyrazole/Pyrazoline-Bearing Benzimidazoles: Searching for New Lead Compounds
  5. An Efficient Synthesis in Water of Novel Oxoquinolines and Their Anticancer Activities
  6. Preclinical Exploration of Newer Curcumin Analog (NSC 793122) as Potential Antiproliferative Agent
  7. Targeting tubulin protein by novel 3,5-disubstituted-1,2,4-triazole analogues as anticancer agents: Design, synthesis, in-vitro, and in-silico studies
  8. Significant advances in catalytic strategies for the synthesis of trisubstituted imidazoles: a review
  9. Design and synthesis of newer 5-aryl- N -(naphthalen-2-yl)-1,3,4-oxadiazol-2-amine analogues as anticancer agents
  10. Innovative Synthesis of 3,5-Disubstituted Pyrazoline with Heterocyclic System for Hybrid Development
  11. Synthesis, anticonvulsant potential, and molecular docking studies of Schiff bases bearing 2', 6-dichloro-2,3'-biquinoline
  12. Pyrazoline Derivatives: Exploring the Synthesis and Development of New Ligands for Anti-Cancer Therapy
  13. Hybrids of Benzimidazole-oxadiazole: A New Avenue for Synthesis, Pharmacological Activity and Recent Patents for the Development of More Effective Ligands
  14. Targeting EGFR by Newer 1-(3,5-Bis((E)-4‑hydroxy-3-methoxystyryl)-1H-pyrazol-1-yl)-2-((substituted phenyl)amino)ethan-1-one Analogues for the Treatment of Cancer: Synthesis, In-vitro and In-silico Studies
  15. A review on innovative approaches in quinoline/isoquinoline synthesis: Unveiling the Pummerer reaction strategy
  16. Pharmacological Evaluation of Bioisosterically Replaced and TriazoleTethered Derivatives for Anticancer Therapy
  17. An Efficient Synthesis of Novel Semicarbazones and Their Biological Activities
  18. Recent Innovations in Synthetic Methodologies and Patent Landscape of Quinoline Analogues: A Comprehensive Review
  19. An Efficient Synthesis of Curcumin Pyrazole Analogues and their Biological Activities
  20. Solvent-free Synthesis, Anticancer Activity and In-Silico Studies of 7-Hydroxy-4-methylquinolin-2(1H)-one Analogues
  21. Targeted Development of Pyrazoline Derivatives for Neurological Disorders: A Review
  22. Synthesis, Characterization, in silico and in vivo Evaluation of Amino Acid Derived Schiff Bases of Quinoline-Benzimidazole Hybrids as Anti-epileptic Agents
  23. Synthetic Strategies of Pyrazoline Derivatives for the Development of New Anticancer Agents: Recent Updates
  24. Translational Research and Clinical Advancements with Nutraceutical Supplements
  25. An Efficient Synthesis of 1-(1,3-Dioxoisoindolin-2-yl)-3-aryl Urea Analogs as Anticancer and Antioxidant Agents: An Insight into Experimental and In Silico Studies
  26. Recent Updates on Synthesis, Biological Activity, and Structure-activity Relationship of 1,3,4-Oxadiazole-quinoline Hybrids: A Review
  27. Design, synthesis and anti-hyperglycemic assessments of novel 5-benzylidenethiazolidine-2,4-dione derivatives as PPAR-γ agonist
  28. Synthesis, Anticancer Activity, and In Silico Studies of 5-(3-Bromophenyl)-N-aryl-4H-1,2,4-triazol-3-amine Analogs
  29. Synthesis of New 4′-(Substituted phenyl)spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones as Antimicrobial, Antitubercular, and Antifungal Agents: An Insight into the ADME and Toxicity Prediction as well as in-silico Molecular Docking Studies
  30. Synthesis and SAR of Potential Anti-Cancer Agents of Quinoline Analogues: A Review
  31. Significant Advancement in Various Synthetic Strategies and Pharmacotherapy of Piperine Derivatives: A Review
  32. Synthesis and Anticancer Evaluation of 4-Chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol Analogues: An Insight into Experimental and Theoretical Studies
  33. Design, Synthesis, ADME, and Anticancer Studies of Newer N-Aryl-5-(3,4,5-Trifluorophenyl)-1,3,4-Oxadiazol-2-Amines: An Insight into Experimental and Theoretical Investigations
  34. Synthesis, Characterization, In Silico and In Vivo Evaluation of Benzimidazole‐Bearing Quinoline Schiff Bases as New Anticonvulsant Agents
  35. Synthesis Anticonvulsant and Cytotoxic Evaluation of Benzimidazole-Quinoline Hybrids Schiff Base Analogs
  36. Synthesis and Biological Evaluation of Octahydroquinazolinones as Phospholipase A2, and Protease Inhibitors: Experimental and Theoretical Exploration
  37. Synthesis, Structure-Activity Relationship, and Biological Activity of Benzimidazole-Quinoline: A Review to Aid in the Design of a New Drug
  38. WITHDRAWN: Recent Advancement on Various Synthetic Strategies and Pharmacotherapy of Piperine and its Derivatives
  39. Synthesis, Anticonvulsant, and Molecular Docking Studies of (3,5-disubstituted-4,5-dihydro-1H-pyrazol-1-yl) (4-chlorophenyl) Methanone Derivatives
  40. Design, Synthesis, In Vivo, and In Silico Evaluation of Benzothiazoles Bearing a 1,3,4-Oxadiazole Moiety as New Antiepileptic Agents
  41. Molecular target interactions of quinoline derivatives as anticancer agents: A review
  42. Fabrication of Silicon Dioxide (SiO2) Nanoparticles Using Wastes of Fruit’s Peel: Characterization and Biological Activities
  43. Synthesis, DFT Analyses, Antiproliferative Activity, and Molecular Docking Studies of Curcumin Analogues
  44. Pyrazoline Containing Compounds as Therapeutic Targets for Neurodegenerative Disorders
  45. Review on the discovery of new Benzimidazole derivatives as Anticancer Agents: Synthesis and Structure-Activity Relationship (2010-2022)
  46. Chemical Modification of Curcumin into Its Semi-Synthetic Analogs Bearing Pyrimidinone Moiety as Anticancer Agents
  47. Levosimendan: mechanistic insight and its diverse future aspects in cardiac care
  48. Transdermal Nutraceuticals Delivery System for CNS Disease
  49. Green Synthesis, Biological Evaluation, and Molecular Docking of 4'-(Substituted Phenyl)Spiro[Indoline-3,3'-[1,2,4]Triazolidine]-2,5'-Diones
  50. Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors
  51. Toward the Discovery of a Novel Class of Leads for High Altitude Disorders by Virtual Screening and Molecular Dynamics Approaches Targeting Carbonic Anhydrase
  52. An Insight into the Structural Requirements and Pharmacophore Identification of Carbonic Anhydrase Inhibitors to Combat Oxidative Stress at High Altitudes: An In-Silico Approach
  53. Green Synthesis of Oxoquinoline-1(2H)-Carboxamide as Antiproliferative and Antioxidant Agents: An Experimental and In-Silico Approach to High Altitude Related Disorders
  54. Synthesis and biological studies of oxoquinolines: Experimental and theoretical investigations
  55. 1,3,4-Oxadiazole Containing Compounds As Therapeutic Targets For Cancer Therapy
  56. Insight into the Isolation, Synthesis, and Structure-Activity Relationship of Piperine Derivatives for the Development of New Compounds: Recent Updates
  57. Ultrasound promoted green synthesis, anticancer evaluation, and molecular docking studies of hydrazines: a pilot trial
  58. Discovery of Structural Prospects of Imidazo[1,5-a]pyrazine Derivatives as BTK Inhibitors Against Cancer: A Computational Study
  59. Pd-HPW/SiO2 Bi-Functional Catalyst: Sonochemical Synthesis, Characterization, and Effect on Octahydroquinazolinone Synthesis
  60. 1,3,4-Oxadiazoles as Potential Pharmacophore for Cytotoxic Potentiality: A Comprehensive Review
  61. Computational Approaches for the Design of Novel Anticancer Compounds Based on Pyrazolo[3,4-d]pyrimidine Derivatives as TRAP1 Inhibitor
  62. Morusflavone, a New Therapeutic Candidate for Prostate Cancer by CYP17A1 Inhibition: Exhibited by Molecular Docking and Dynamics Simulation
  63. Machine Learning in Drug Discovery: A Review
  64. Ultrasound promoted synthesis of N-(substituted phenyl)-2-(7‑hydroxy-4-methyl-2H-chromen-2-ylidene)hydrazine-1-carboxamides as cytotoxic and antioxidant agents
  65. Synthesis, Biological Evaluation and Molecular Docking Studies Against EGFR Tyrosine Kinase of 3,5-bis(substituted benzylidene)-1- ethylpiperidin-4-one Analogues
  66. Molecular Engineering of Curcumin, an Active Constituent of Curcuma longa L. (Turmeric) of the Family Zingiberaceae with Improved Antiproliferative Activity
  67. Benzimidazole-Quinoline Hybrid Scaffold as Promising Pharmacological Agents: A Review
  68. Synthesis and Biological Evaluations of N-(4-Substituted Phenyl)-7-Hydroxy-4-Methyl-2-Oxoquinoline-1(2H)-Carbothioamides
  69. Design, synthesis, anticancer evaluation and molecular docking studies of chalcone linked pyrido[4,3-b]pyrazin-5(6H)-one derivatives
  70. Design, Synthesis and Evaluation of Hybrid 2-Heteroaryl BenzimidazoleChalcone Derivatives as Anticancer Agents
  71. Synthesis and Anticancer Potentials of Quinoline Analogues: A Review of Literature
  72. Advancement in Nanotheranostics for Effective Skin Cancer Therapy: State of the Art
  73. Design, synthesis, and biological evaluation of chalcone-linked thiazole-imidazopyridine derivatives as anticancer agents
  74. Synthesis, Antiproliferative, and Antioxidant Activities of Substituted N-[(1,3,4-Oxadiazol-2-yl) Methyl] Benzamines
  75. Synthesis and Biological Potentials of 5-aryl-N-[4-(trifluoromethyl) phenyl]-1,3,4-oxadiazol-2-amines
  76. SYNTHESIS, AND EVALUATION OF COUMARIN HYBRIDS AS ANTIMYCOBACTERIAL AGENTS
  77. 2‐Mercapto Benzthiazole Coupled Benzyl Triazoles as New COX‐2 Inhibitors: Design, Synthesis, Biological Testing and Molecular Modeling Studies
  78. Synthesis and Biological Potentials of Quinoline Analogues: A Review of Literature
  79. Ultrasound-assisted extraction of some branded tea: Optimization based on polyphenol content, antioxidant potential and thermodynamic study
  80. Cost-effective and eco-friendly synthesis of titanium dioxide (TiO2) nanoparticles using fruit’s peel agro-waste extracts: characterization, in vitro antibacterial, antioxidant activities
  81. Recent insights on nanomedicine for augmented infection control
  82. Plasmodium falciparum PFI1625c offers an opportunity to design potent anti-malarials: Biochemical characterization and testing potentials in drug discovery
  83. Aurone: A biologically attractive scaffold as anticancer agent
  84. A review on HCV inhibitors: Significance of non-structural polyproteins
  85. Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of N-(7- hydroxy-4-methyl-2-oxoquinolin-1(2H)-yl)acetamide/benzamide Analogues
  86. Synthesis and cytotoxicity evaluation of [(2,4-dichlorophenoxy)methyl]-5-aryl-1,3,4-oxadiazole/4 H -1,2,4-triazole analogues
  87. Design, Synthesis and Biological Evaluation of 2 (((5-aryl-1,2,4-oxadiazol-3-yl)methyl)thio)benzo[d]oxazoles: New Antiinflammatory and Antioxidant Agents
  88. Synthesis of new C-dimethylated chalcones as potent antitubercular agents
  89. Design, Synthesis and Biological Evaluation of Benzothiazole-thiophene Hybrids: A New Class of Potent Antimicrobial Agents
  90. Synthesis and Cytotoxic Evaluation of 3-(4-Fluorophenyl)-4,5-dihydro-5-(3,4,5-trimethoxy/4-nitrophenyl)-N-(substituted-phenyl)pyrazole-1-carboxamide Analogues
  91. Rationale Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1,3,4-oxadiazole Analogues
  92. Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of New Oxadiazole Analogues
  93. Synthesis and biological potentials of some new 1,3,4-oxadiazole analogues
  94. Synthesis, Characterization, Docking and Study of Inhibitory Action of Some Novel C-Alkylated Chalcones on 5-LOX Enzyme
  95. Nanocarriers in advanced drug targeting: setting novel paradigm in cancer therapeutics
  96. Antitubercular Agents and Tubercular Vaccines in Clinical Trials
  97. Updates on synthesis and biological activities of 1,3,4-oxadiazole: A review
  98. In silico identification of novel antagonists and binding insights by structural and functional analyses of guanylate kinase of Leishmania donovani and interaction with inhibitors
  99. Anticonvulsant activity and neuroprotection assay of 3-substituted-N-aryl-6,7-dimethoxy-3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide analogues
  100. In vivo anti-inflammatory activity and docking study of newly synthesized benzimidazole derivatives bearing oxadiazole and morpholine rings
  101. Synthesis, Biological Evaluation and Molecular Docking Studies of Pyridine Incorporated Chalcone Derivatives as Anticancer Agents
  102. Physicochemical characterization of benzalkonium chloride and urea based deep eutectic solvent (DES): A novel catalyst for the efficient synthesis of isoxazolines under ultrasonic irradiation
  103. ChemInform Abstract: Therapeutic Potential of Coumarins as Antiviral Agents
  104. Therapeutic potential of coumarins as antiviral agents
  105. Rationale Design, Synthesis AndIn VitroAnticancer Activity of New 2,5-Disubstituted-1,3,4-Oxadiazole Analogues
  106. Synthesis and antimicrobial activity of N1-(3-chloro-4-fluorophenyl)-N4-substituted semicarbazone derivatives
  107. Design and synthesis of new 2,5-disubstituted-1,3,4-oxadiazole analogues as anticancer agents
  108. In vitro studies of the antileishmanial activity of the newer 2-(substitutedphenoxy)-N-[(aryl)methylidene]acetohydrazide analogues
  109. Evaluation of Anticancer Activity of Curcumin Analogues Bearing a Heterocyclic Nucleus
  110. Synthesis, antitumor evaluation, and molecular docking studies of indole–indazolyl hydrazide–hydrazone derivatives
  111. Synthesis and Antiproliferative Activity of Some Quinoline and Oxadiazole Derivatives
  112. Synthesis, Anticancer Activity and Molecular Docking Studies of Newer Quinoline Analogues
  113. Synthesis of N-{[5-aryl/alkyl-1,3,4-oxadiazol-2-yl]methyl}pyridin-2-amine as Antimicrobial and Anticancer Agents
  114. Synthesis, antiproliferative activity, and molecular docking studies of curcumin analogues bearing pyrazole ring
  115. Hydrazones as a Privileged Structural Linker in Antitubercular Agents: A Review
  116. Recent advances in the development of vaccines for tuberculosis
  117. Ebola Virus: Current and Future Perspectives
  118. Tuberculosis: Current Treatment, Diagnostics, and Newer Antitubercular Agents in Clinical Trials
  119. Molecular modelling, synthesis, and antimalarial potentials of curcumin analogues containing heterocyclic ring
  120. Synthesis and biological evaluation of 1,3,4-oxadiazole-linked bisindole derivatives as anticancer agents
  121. Design and synthesis of 3-(4-aminophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carboxamide/carbothioamide analogues as antitubercular agents
  122. Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach
  123. Synthesis, characterization and anticancer evaluation of 2-(naphthalen-1-ylmethyl/naphthalen-2-yloxymethyl)-1-[5-(substituted phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-1H-benzimidazole
  124. Simple, efficient, and improved synthesis of Biginelli-type compounds of curcumin as anticancer agents
  125. Synthesis, Anticonvulsant and Neurotoxicity Evaluation of Some Newer N-(2-benzoylbenzofuran-3-yl)-3-(substituted)-propanamide Analogs
  126. Tuberculosis Vaccines: Hopes and Hurdles
  127. Synthesis of 2,5-Disubstituted-1,3,4-oxadiazole Analogs as Novel Anticancer and Antimicrobial Agents
  128. Synthesis and Anticancer Activity ofN-Aryl-5-substituted-1,3,4-oxadiazol-2-amine Analogues
  129. Psychomotor Seizure Test, Neurotoxicity and in vitro Neuroprotection Assay of some Semicarbazone Analogues
  130. Semicarbazone Analogs as Anticonvulsant Agents: A Review
  131. Synthesis of 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6-(substituted phenyl)pyrimidin-2-ol Analogues as Anti-Inflammatory and Analgesic Agents
  132. Synthesis, Characterisation, andIn VitroAnticancer Activity of Curcumin Analogues Bearing Pyrazole/Pyrimidine Ring Targeting EGFR Tyrosine Kinase
  133. Synthesis, Anticancer and Molecular Docking Studies of 2-(4-chlorophenyl)-5-aryl-1,3,4-Oxadiazole Analogues
  134. POMA analyses as new efficient bioinformatics’ platform to predict and optimise bioactivity of synthesized 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  135. Corrigendum to “POMA analyses as new efficient bioinformatics’ platform to predict and optimise bioactivity of synthesized 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues” [Bioorg. Med. Chem. Lett. 22 (2012) 7029–7035]
  136. Synthesis and anticonvulsant evaluation of 2-(substituted benzylidene/ethylidene)-N-(substituted phenyl)hydrazinecarboxamide analogues
  137. Synthesis and Anticancer Activity of 3a,4-dihydro-3H-indeno[1, 2-c]pyrazole-2-carboxamide Analogues
  138. 1,3,4-Oxadiazole: A Biologically Active Scaffold
  139. Molecular Properties Prediction and Synthesis of Novel Pyrazoline Carboxamide Analogs as Antitubercular Agents
  140. Synthesis and Biological Evaluation of N-[2-(substituted-phenyl)-4-oxo-1,3- thiazolidin-3-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide Analogs as Potential Antibacterial and Antifungal Agents
  141. Synthesis and anticonvulsant activity of 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  142. ChemInform Abstract: Synthesis and Antimycobacterial Evaluation of 3a,4-Dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide Analogues.
  143. Discovery of Novel 1,4-Benzodioxane Containing Thiazolidinone Derivatives as Potential Antihepatotoxic Agent
  144. Discovery of novel antitubercular 1,5-dimethyl-2-phenyl-4-([5-(arylamino)-1,3,4-oxadiazol-2-yl]methylamino)-1,2-dihydro-3H-pyrazol-3-one analogues
  145. ChemInform Abstract: Discovery of Novel Antitubercular 3a,4-Dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide Analogues.
  146. Molecular properties prediction and synthesis of novel 1,3,4-oxadiazole analogues as potent antimicrobial and antitubercular agents
  147. Synthesis and antihepatotoxic activity of 5-(2,3-dihydro-1,4-benzodioxane-6-yl)-3-substituted-phenyl-4,5-dihydro-1H-pyrazole derivatives
  148. Synthesis and antimycobacterial evaluation of 3a,4-dihydro-3H-indeno [1,2-c] pyrazole-2-carboxamide analogues
  149. Discovery of novel antitubercular 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  150. Design, synthesis and antimycobacterial evaluation of novel 3-substituted-N-aryl-6,7-dimethoxy-3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide analogues
  151. ChemInform Abstract: Design, Synthesis and Evaluation of Novel 5,6-Dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4-substituted Phenyl Methanone Analogues.
  152. Synthesis and antimycobacterial evaluation of novel 5,6-dimethoxy-1-oxo-2,5-dihydro-1H-2-indenyl-5,4-substituted phenyl methanone analogues
  153. Design, synthesis and evaluation of novel 5,6-dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4-substituted phenyl methanone analogues