All Stories

  1. Hybrids of Benzimidazole-oxadiazole: A New Avenue for Synthesis, Pharmacological Activity and Recent Patents for the Development of More Effective Ligands
  2. An Efficient Synthesis of Curcumin Pyrazole Analogues and their Biological Activities
  3. Solvent-free Synthesis, Anticancer Activity and In-Silico Studies of 7-Hydroxy-4-methylquinolin-2(1H)-one Analogues
  4. Targeted Development of Pyrazoline Derivatives for Neurological Disorders: A Review
  5. Synthesis, Characterization, in silico and in vivo Evaluation of Amino Acid Derived Schiff Bases of Quinoline-Benzimidazole Hybrids as Anti-epileptic Agents
  6. Synthetic Strategies of Pyrazoline Derivatives for the Development of New Anticancer Agents: Recent Updates
  7. An Efficient Synthesis of 1-(1,3-Dioxoisoindolin-2-yl)-3-aryl Urea Analogs as Anticancer and Antioxidant Agents: An Insight into Experimental and In Silico Studies
  8. Recent Updates on Synthesis, Biological Activity, and Structure-activity Relationship of 1,3,4-Oxadiazole-quinoline Hybrids: A Review
  9. Design, synthesis and anti-hyperglycemic assessments of novel 5-benzylidenethiazolidine-2,4-dione derivatives as PPAR-γ agonist
  10. Synthesis, Anticancer Activity, and In Silico Studies of 5-(3-Bromophenyl)-N-aryl-4H-1,2,4-triazol-3-amine Analogs
  11. Synthesis of New 4′-(Substituted phenyl)spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones as Antimicrobial, Antitubercular, and Antifungal Agents: An Insight into the ADME and Toxicity Prediction as well as in-silico Molecular Docking Studies
  12. Synthesis and SAR of Potential Anti-Cancer Agents of Quinoline Analogues: A Review
  13. Significant Advancement in Various Synthetic Strategies and Pharmacotherapy of Piperine Derivatives: A Review
  14. Synthesis and Anticancer Evaluation of 4-Chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol Analogues: An Insight into Experimental and Theoretical Studies
  15. Design, Synthesis, ADME, and Anticancer Studies of Newer N-Aryl-5-(3,4,5-Trifluorophenyl)-1,3,4-Oxadiazol-2-Amines: An Insight into Experimental and Theoretical Investigations
  16. Synthesis, Characterization, In Silico and In Vivo Evaluation of Benzimidazole‐Bearing Quinoline Schiff Bases as New Anticonvulsant Agents
  17. Synthesis Anticonvulsant and Cytotoxic Evaluation of Benzimidazole-Quinoline Hybrids Schiff Base Analogs
  18. Synthesis and Biological Evaluation of Octahydroquinazolinones as Phospholipase A2, and Protease Inhibitors: Experimental and Theoretical Exploration
  19. Synthesis, Structure-Activity Relationship, and Biological Activity of Benzimidazole-Quinoline: A Review to Aid in the Design of a New Drug
  20. WITHDRAWN: Recent Advancement on Various Synthetic Strategies and Pharmacotherapy of Piperine and its Derivatives
  21. Synthesis, Anticonvulsant, and Molecular Docking Studies of (3,5-disubstituted-4,5-dihydro-1H-pyrazol-1-yl) (4-chlorophenyl) Methanone Derivatives
  22. Design, Synthesis, In Vivo, and In Silico Evaluation of Benzothiazoles Bearing a 1,3,4-Oxadiazole Moiety as New Antiepileptic Agents
  23. Molecular target interactions of quinoline derivatives as anticancer agents: A review
  24. Fabrication of Silicon Dioxide (SiO2) Nanoparticles Using Wastes of Fruit’s Peel: Characterization and Biological Activities
  25. Synthesis, DFT Analyses, Antiproliferative Activity, and Molecular Docking Studies of Curcumin Analogues
  26. Pyrazoline Containing Compounds as Therapeutic Targets for Neurodegenerative Disorders
  27. Review on the discovery of new Benzimidazole derivatives as Anticancer Agents: Synthesis and Structure-Activity Relationship (2010-2022)
  28. Chemical Modification of Curcumin into Its Semi-Synthetic Analogs Bearing Pyrimidinone Moiety as Anticancer Agents
  29. Levosimendan: mechanistic insight and its diverse future aspects in cardiac care
  30. Transdermal Nutraceuticals Delivery System for CNS Disease
  31. Green Synthesis, Biological Evaluation, and Molecular Docking of 4'-(Substituted Phenyl)Spiro[Indoline-3,3'-[1,2,4]Triazolidine]-2,5'-Diones
  32. Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors
  33. Toward the Discovery of a Novel Class of Leads for High Altitude Disorders by Virtual Screening and Molecular Dynamics Approaches Targeting Carbonic Anhydrase
  34. An Insight into the Structural Requirements and Pharmacophore Identification of Carbonic Anhydrase Inhibitors to Combat Oxidative Stress at High Altitudes: An In-Silico Approach
  35. Green Synthesis of Oxoquinoline-1(2H)-Carboxamide as Antiproliferative and Antioxidant Agents: An Experimental and In-Silico Approach to High Altitude Related Disorders
  36. Synthesis and biological studies of oxoquinolines: Experimental and theoretical investigations
  37. 1,3,4-Oxadiazole Containing Compounds As Therapeutic Targets For Cancer Therapy
  38. Insight into the Isolation, Synthesis, and Structure-Activity Relationship of Piperine Derivatives for the Development of New Compounds: Recent Updates
  39. Ultrasound promoted green synthesis, anticancer evaluation, and molecular docking studies of hydrazines: a pilot trial
  40. Discovery of Structural Prospects of Imidazo[1,5-a]pyrazine Derivatives as BTK Inhibitors Against Cancer: A Computational Study
  41. Pd-HPW/SiO2 Bi-Functional Catalyst: Sonochemical Synthesis, Characterization, and Effect on Octahydroquinazolinone Synthesis
  42. 1,3,4-Oxadiazoles as Potential Pharmacophore for Cytotoxic Potentiality: A Comprehensive Review
  43. Computational Approaches for the Design of Novel Anticancer Compounds Based on Pyrazolo[3,4-d]pyrimidine Derivatives as TRAP1 Inhibitor
  44. Morusflavone, a New Therapeutic Candidate for Prostate Cancer by CYP17A1 Inhibition: Exhibited by Molecular Docking and Dynamics Simulation
  45. Machine Learning in Drug Discovery: A Review
  46. Ultrasound promoted synthesis of N-(substituted phenyl)-2-(7‑hydroxy-4-methyl-2H-chromen-2-ylidene)hydrazine-1-carboxamides as cytotoxic and antioxidant agents
  47. Synthesis, Biological Evaluation and Molecular Docking Studies Against EGFR Tyrosine Kinase of 3,5-bis(substituted benzylidene)-1- ethylpiperidin-4-one Analogues
  48. Molecular Engineering of Curcumin, an Active Constituent of Curcuma longa L. (Turmeric) of the Family Zingiberaceae with Improved Antiproliferative Activity
  49. Benzimidazole-Quinoline Hybrid Scaffold as Promising Pharmacological Agents: A Review
  50. Synthesis and Biological Evaluations of N-(4-Substituted Phenyl)-7-Hydroxy-4-Methyl-2-Oxoquinoline-1(2H)-Carbothioamides
  51. Design, synthesis, anticancer evaluation and molecular docking studies of chalcone linked pyrido[4,3-b]pyrazin-5(6H)-one derivatives
  52. Design, Synthesis and Evaluation of Hybrid 2-Heteroaryl BenzimidazoleChalcone Derivatives as Anticancer Agents
  53. Synthesis and Anticancer Potentials of Quinoline Analogues: A Review of Literature
  54. Advancement in Nanotheranostics for Effective Skin Cancer Therapy: State of the Art
  55. Design, synthesis, and biological evaluation of chalcone-linked thiazole-imidazopyridine derivatives as anticancer agents
  56. Synthesis, Antiproliferative, and Antioxidant Activities of Substituted N-[(1,3,4-Oxadiazol-2-yl) Methyl] Benzamines
  57. Synthesis and Biological Potentials of 5-aryl-N-[4-(trifluoromethyl) phenyl]-1,3,4-oxadiazol-2-amines
  58. SYNTHESIS, AND EVALUATION OF COUMARIN HYBRIDS AS ANTIMYCOBACTERIAL AGENTS
  59. 2‐Mercapto Benzthiazole Coupled Benzyl Triazoles as New COX‐2 Inhibitors: Design, Synthesis, Biological Testing and Molecular Modeling Studies
  60. Synthesis and Biological Potentials of Quinoline Analogues: A Review of Literature
  61. Ultrasound-assisted extraction of some branded tea: Optimization based on polyphenol content, antioxidant potential and thermodynamic study
  62. Cost-effective and eco-friendly synthesis of titanium dioxide (TiO2) nanoparticles using fruit’s peel agro-waste extracts: characterization, in vitro antibacterial, antioxidant activities
  63. Recent insights on nanomedicine for augmented infection control
  64. Plasmodium falciparum PFI1625c offers an opportunity to design potent anti-malarials: Biochemical characterization and testing potentials in drug discovery
  65. Aurone: A biologically attractive scaffold as anticancer agent
  66. A review on HCV inhibitors: Significance of non-structural polyproteins
  67. Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of N-(7- hydroxy-4-methyl-2-oxoquinolin-1(2H)-yl)acetamide/benzamide Analogues
  68. Synthesis and cytotoxicity evaluation of [(2,4-dichlorophenoxy)methyl]-5-aryl-1,3,4-oxadiazole/4 H -1,2,4-triazole analogues
  69. Design, Synthesis and Biological Evaluation of 2 (((5-aryl-1,2,4-oxadiazol-3-yl)methyl)thio)benzo[d]oxazoles: New Antiinflammatory and Antioxidant Agents
  70. Synthesis of new C-dimethylated chalcones as potent antitubercular agents
  71. Design, Synthesis and Biological Evaluation of Benzothiazole-thiophene Hybrids: A New Class of Potent Antimicrobial Agents
  72. Synthesis and Cytotoxic Evaluation of 3-(4-Fluorophenyl)-4,5-dihydro-5-(3,4,5-trimethoxy/4-nitrophenyl)-N-(substituted-phenyl)pyrazole-1-carboxamide Analogues
  73. Rationale Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1,3,4-oxadiazole Analogues
  74. Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of New Oxadiazole Analogues
  75. Synthesis and biological potentials of some new 1,3,4-oxadiazole analogues
  76. Synthesis, Characterization, Docking and Study of Inhibitory Action of Some Novel C-Alkylated Chalcones on 5-LOX Enzyme
  77. Nanocarriers in advanced drug targeting: setting novel paradigm in cancer therapeutics
  78. Antitubercular Agents and Tubercular Vaccines in Clinical Trials
  79. Updates on synthesis and biological activities of 1,3,4-oxadiazole: A review
  80. In silico identification of novel antagonists and binding insights by structural and functional analyses of guanylate kinase of Leishmania donovani and interaction with inhibitors
  81. Anticonvulsant activity and neuroprotection assay of 3-substituted-N-aryl-6,7-dimethoxy-3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide analogues
  82. In vivo anti-inflammatory activity and docking study of newly synthesized benzimidazole derivatives bearing oxadiazole and morpholine rings
  83. Synthesis, Biological Evaluation and Molecular Docking Studies of Pyridine Incorporated Chalcone Derivatives as Anticancer Agents
  84. Physicochemical characterization of benzalkonium chloride and urea based deep eutectic solvent (DES): A novel catalyst for the efficient synthesis of isoxazolines under ultrasonic irradiation
  85. ChemInform Abstract: Therapeutic Potential of Coumarins as Antiviral Agents
  86. Therapeutic potential of coumarins as antiviral agents
  87. Rationale Design, Synthesis AndIn VitroAnticancer Activity of New 2,5-Disubstituted-1,3,4-Oxadiazole Analogues
  88. Synthesis and antimicrobial activity of N1-(3-chloro-4-fluorophenyl)-N4-substituted semicarbazone derivatives
  89. Design and synthesis of new 2,5-disubstituted-1,3,4-oxadiazole analogues as anticancer agents
  90. In vitro studies of the antileishmanial activity of the newer 2-(substitutedphenoxy)-N-[(aryl)methylidene]acetohydrazide analogues
  91. Evaluation of Anticancer Activity of Curcumin Analogues Bearing a Heterocyclic Nucleus
  92. Synthesis, antitumor evaluation, and molecular docking studies of indole–indazolyl hydrazide–hydrazone derivatives
  93. Synthesis and Antiproliferative Activity of Some Quinoline and Oxadiazole Derivatives
  94. Synthesis, Anticancer Activity and Molecular Docking Studies of Newer Quinoline Analogues
  95. Synthesis of N-{[5-aryl/alkyl-1,3,4-oxadiazol-2-yl]methyl}pyridin-2-amine as Antimicrobial and Anticancer Agents
  96. Synthesis, antiproliferative activity, and molecular docking studies of curcumin analogues bearing pyrazole ring
  97. Hydrazones as a Privileged Structural Linker in Antitubercular Agents: A Review
  98. Recent advances in the development of vaccines for tuberculosis
  99. Ebola Virus: Current and Future Perspectives
  100. Tuberculosis: Current Treatment, Diagnostics, and Newer Antitubercular Agents in Clinical Trials
  101. Molecular modelling, synthesis, and antimalarial potentials of curcumin analogues containing heterocyclic ring
  102. Synthesis and biological evaluation of 1,3,4-oxadiazole-linked bisindole derivatives as anticancer agents
  103. Design and synthesis of 3-(4-aminophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carboxamide/carbothioamide analogues as antitubercular agents
  104. Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach
  105. Synthesis, characterization and anticancer evaluation of 2-(naphthalen-1-ylmethyl/naphthalen-2-yloxymethyl)-1-[5-(substituted phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-1H-benzimidazole
  106. Simple, efficient, and improved synthesis of Biginelli-type compounds of curcumin as anticancer agents
  107. Synthesis, Anticonvulsant and Neurotoxicity Evaluation of Some Newer N-(2-benzoylbenzofuran-3-yl)-3-(substituted)-propanamide Analogs
  108. Tuberculosis Vaccines: Hopes and Hurdles
  109. Synthesis of 2,5-Disubstituted-1,3,4-oxadiazole Analogs as Novel Anticancer and Antimicrobial Agents
  110. Synthesis and Anticancer Activity ofN-Aryl-5-substituted-1,3,4-oxadiazol-2-amine Analogues
  111. Psychomotor Seizure Test, Neurotoxicity and in vitro Neuroprotection Assay of some Semicarbazone Analogues
  112. Semicarbazone Analogs as Anticonvulsant Agents: A Review
  113. Synthesis of 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6-(substituted phenyl)pyrimidin-2-ol Analogues as Anti-Inflammatory and Analgesic Agents
  114. Synthesis, Characterisation, andIn VitroAnticancer Activity of Curcumin Analogues Bearing Pyrazole/Pyrimidine Ring Targeting EGFR Tyrosine Kinase
  115. Synthesis, Anticancer and Molecular Docking Studies of 2-(4-chlorophenyl)-5-aryl-1,3,4-Oxadiazole Analogues
  116. POMA analyses as new efficient bioinformatics’ platform to predict and optimise bioactivity of synthesized 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  117. Corrigendum to “POMA analyses as new efficient bioinformatics’ platform to predict and optimise bioactivity of synthesized 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues” [Bioorg. Med. Chem. Lett. 22 (2012) 7029–7035]
  118. Synthesis and anticonvulsant evaluation of 2-(substituted benzylidene/ethylidene)-N-(substituted phenyl)hydrazinecarboxamide analogues
  119. Synthesis and Anticancer Activity of 3a,4-dihydro-3H-indeno[1, 2-c]pyrazole-2-carboxamide Analogues
  120. 1,3,4-Oxadiazole: A Biologically Active Scaffold
  121. Molecular Properties Prediction and Synthesis of Novel Pyrazoline Carboxamide Analogs as Antitubercular Agents
  122. Synthesis and Biological Evaluation of N-[2-(substituted-phenyl)-4-oxo-1,3- thiazolidin-3-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide Analogs as Potential Antibacterial and Antifungal Agents
  123. Synthesis and anticonvulsant activity of 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  124. ChemInform Abstract: Synthesis and Antimycobacterial Evaluation of 3a,4-Dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide Analogues.
  125. Discovery of Novel 1,4-Benzodioxane Containing Thiazolidinone Derivatives as Potential Antihepatotoxic Agent
  126. Discovery of novel antitubercular 1,5-dimethyl-2-phenyl-4-([5-(arylamino)-1,3,4-oxadiazol-2-yl]methylamino)-1,2-dihydro-3H-pyrazol-3-one analogues
  127. ChemInform Abstract: Discovery of Novel Antitubercular 3a,4-Dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide Analogues.
  128. Molecular properties prediction and synthesis of novel 1,3,4-oxadiazole analogues as potent antimicrobial and antitubercular agents
  129. Synthesis and antihepatotoxic activity of 5-(2,3-dihydro-1,4-benzodioxane-6-yl)-3-substituted-phenyl-4,5-dihydro-1H-pyrazole derivatives
  130. Synthesis and antimycobacterial evaluation of 3a,4-dihydro-3H-indeno [1,2-c] pyrazole-2-carboxamide analogues
  131. Discovery of novel antitubercular 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  132. Design, synthesis and antimycobacterial evaluation of novel 3-substituted-N-aryl-6,7-dimethoxy-3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide analogues
  133. ChemInform Abstract: Design, Synthesis and Evaluation of Novel 5,6-Dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4-substituted Phenyl Methanone Analogues.
  134. Synthesis and antimycobacterial evaluation of novel 5,6-dimethoxy-1-oxo-2,5-dihydro-1H-2-indenyl-5,4-substituted phenyl methanone analogues
  135. Design, synthesis and evaluation of novel 5,6-dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4-substituted phenyl methanone analogues