All Stories

  1. Synthetic Strategies of Pyrazoline Derivatives for the Development of New Anticancer Agents: Recent Updates
  2. Recent Updates on Synthesis, Biological Activity, and Structure-activity Relationship of 1,3,4-Oxadiazole-quinoline Hybrids: A Review
  3. Synthesis of New 4′-(Substituted phenyl)spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones as Antimicrobial, Antitubercular, and Antifungal Agents: An Insight into the ADME and Toxicity Prediction as well as in-silico Molecular Docking Studies
  4. Synthesis and SAR of Potential Anti-Cancer Agents of Quinoline Analogues: A Review
  5. Synthesis and Anticancer Evaluation of 4-Chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol Analogues: An Insight into Experimental and Theoretical Studies
  6. Design, Synthesis, ADME, and Anticancer Studies of Newer N-Aryl-5-(3,4,5-Trifluorophenyl)-1,3,4-Oxadiazol-2-Amines: An Insight into Experimental and Theoretical Investigations
  7. Synthesis, Characterization, In Silico and In Vivo Evaluation of Benzimidazole‐Bearing Quinoline Schiff Bases as New Anticonvulsant Agents
  8. Synthesis and Biological Evaluation of Octahydroquinazolinones as Phospholipase A2, and Protease Inhibitors: Experimental and Theoretical Exploration
  9. Synthesis, Structure-Activity Relationship, and Biological Activity of Benzimidazole-Quinoline: A Review to Aid in the Design of a New Drug
  10. WITHDRAWN: Recent Advancement on Various Synthetic Strategies and Pharmacotherapy of Piperine and its Derivatives
  11. Synthesis, Anticonvulsant, and Molecular Docking Studies of (3,5-disubstituted-4,5-dihydro-1H-pyrazol-1-yl) (4-chlorophenyl) Methanone Derivatives
  12. Design, Synthesis, In Vivo, and In Silico Evaluation of Benzothiazoles Bearing a 1,3,4-Oxadiazole Moiety as New Antiepileptic Agents
  13. Molecular target interactions of quinoline derivatives as anticancer agents: A review
  14. Fabrication of Silicon Dioxide (SiO2) Nanoparticles Using Wastes of Fruit’s Peel: Characterization and Biological Activities
  15. Synthesis, DFT Analyses, Antiproliferative Activity, and Molecular Docking Studies of Curcumin Analogues
  16. Pyrazoline Containing Compounds as Therapeutic Targets for Neurodegenerative Disorders
  17. Review on the discovery of new Benzimidazole derivatives as Anticancer Agents: Synthesis and Structure-Activity Relationship (2010-2022)
  18. Chemical Modification of Curcumin into Its Semi-Synthetic Analogs Bearing Pyrimidinone Moiety as Anticancer Agents
  19. Levosimendan: mechanistic insight and its diverse future aspects in cardiac care
  20. Transdermal Nutraceuticals Delivery System for CNS Disease
  21. Green Synthesis, Biological Evaluation, and Molecular Docking of 4'-(Substituted Phenyl)Spiro[Indoline-3,3'-[1,2,4]Triazolidine]-2,5'-Diones
  22. Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors
  23. Toward the Discovery of a Novel Class of Leads for High Altitude Disorders by Virtual Screening and Molecular Dynamics Approaches Targeting Carbonic Anhydrase
  24. An Insight into the Structural Requirements and Pharmacophore Identification of Carbonic Anhydrase Inhibitors to Combat Oxidative Stress at High Altitudes: An In-Silico Approach
  25. Green Synthesis of Oxoquinoline-1(2H)-Carboxamide as Antiproliferative and Antioxidant Agents: An Experimental and In-Silico Approach to High Altitude Related Disorders
  26. Synthesis and biological studies of oxoquinolines: Experimental and theoretical investigations
  27. 1,3,4-Oxadiazole Containing Compounds As Therapeutic Targets For Cancer Therapy
  28. Insight into the Isolation, Synthesis, and Structure-Activity Relationship of Piperine Derivatives for the Development of New Compounds: Recent Updates
  29. Ultrasound promoted green synthesis, anticancer evaluation, and molecular docking studies of hydrazines: a pilot trial
  30. Discovery of Structural Prospects of Imidazo[1,5-a]pyrazine Derivatives as BTK Inhibitors Against Cancer: A Computational Study
  31. Pd-HPW/SiO2 Bi-Functional Catalyst: Sonochemical Synthesis, Characterization, and Effect on Octahydroquinazolinone Synthesis
  32. 1,3,4-Oxadiazoles as Potential Pharmacophore for Cytotoxic Potentiality: A Comprehensive Review
  33. Computational Approaches for the Design of Novel Anticancer Compounds Based on Pyrazolo[3,4-d]pyrimidine Derivatives as TRAP1 Inhibitor
  34. Morusflavone, a New Therapeutic Candidate for Prostate Cancer by CYP17A1 Inhibition: Exhibited by Molecular Docking and Dynamics Simulation
  35. Machine Learning in Drug Discovery: A Review
  36. Ultrasound promoted synthesis of N-(substituted phenyl)-2-(7‑hydroxy-4-methyl-2H-chromen-2-ylidene)hydrazine-1-carboxamides as cytotoxic and antioxidant agents
  37. Synthesis, Biological Evaluation and Molecular Docking Studies Against EGFR Tyrosine Kinase of 3,5-bis(substituted benzylidene)-1- ethylpiperidin-4-one Analogues
  38. Molecular Engineering of Curcumin, an Active Constituent of Curcuma longa L. (Turmeric) of the Family Zingiberaceae with Improved Antiproliferative Activity
  39. Benzimidazole-Quinoline Hybrid Scaffold as Promising Pharmacological Agents: A Review
  40. Synthesis and Biological Evaluations of N-(4-Substituted Phenyl)-7-Hydroxy-4-Methyl-2-Oxoquinoline-1(2H)-Carbothioamides
  41. Design, synthesis, anticancer evaluation and molecular docking studies of chalcone linked pyrido[4,3-b]pyrazin-5(6H)-one derivatives
  42. Design, Synthesis and Evaluation of Hybrid 2-Heteroaryl BenzimidazoleChalcone Derivatives as Anticancer Agents
  43. Synthesis and Anticancer Potentials of Quinoline Analogues: A Review of Literature
  44. Advancement in Nanotheranostics for Effective Skin Cancer Therapy: State of the Art
  45. Design, synthesis, and biological evaluation of chalcone-linked thiazole-imidazopyridine derivatives as anticancer agents
  46. Synthesis, Antiproliferative, and Antioxidant Activities of Substituted N-[(1,3,4-Oxadiazol-2-yl) Methyl] Benzamines
  47. Synthesis and Biological Potentials of 5-aryl-N-[4-(trifluoromethyl) phenyl]-1,3,4-oxadiazol-2-amines
  49. 2‐Mercapto Benzthiazole Coupled Benzyl Triazoles as New COX‐2 Inhibitors: Design, Synthesis, Biological Testing and Molecular Modeling Studies
  50. Synthesis and Biological Potentials of Quinoline Analogues: A Review of Literature
  51. Ultrasound-assisted extraction of some branded tea: Optimization based on polyphenol content, antioxidant potential and thermodynamic study
  52. Cost-effective and eco-friendly synthesis of titanium dioxide (TiO2) nanoparticles using fruit’s peel agro-waste extracts: characterization, in vitro antibacterial, antioxidant activities
  53. Recent insights on nanomedicine for augmented infection control
  54. Plasmodium falciparum PFI1625c offers an opportunity to design potent anti-malarials: Biochemical characterization and testing potentials in drug discovery
  55. Aurone: A biologically attractive scaffold as anticancer agent
  56. A review on HCV inhibitors: Significance of non-structural polyproteins
  57. Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of N-(7- hydroxy-4-methyl-2-oxoquinolin-1(2H)-yl)acetamide/benzamide Analogues
  58. Synthesis and cytotoxicity evaluation of [(2,4-dichlorophenoxy)methyl]-5-aryl-1,3,4-oxadiazole/4 H -1,2,4-triazole analogues
  59. Design, Synthesis and Biological Evaluation of 2 (((5-aryl-1,2,4-oxadiazol-3-yl)methyl)thio)benzo[d]oxazoles: New Antiinflammatory and Antioxidant Agents
  60. Synthesis of new C-dimethylated chalcones as potent antitubercular agents
  61. Design, Synthesis and Biological Evaluation of Benzothiazole-thiophene Hybrids: A New Class of Potent Antimicrobial Agents
  62. Synthesis and Cytotoxic Evaluation of 3-(4-Fluorophenyl)-4,5-dihydro-5-(3,4,5-trimethoxy/4-nitrophenyl)-N-(substituted-phenyl)pyrazole-1-carboxamide Analogues
  63. Rationale Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1,3,4-oxadiazole Analogues
  64. Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of New Oxadiazole Analogues
  65. Synthesis and biological potentials of some new 1,3,4-oxadiazole analogues
  66. Synthesis, Characterization, Docking and Study of Inhibitory Action of Some Novel C-Alkylated Chalcones on 5-LOX Enzyme
  67. Nanocarriers in advanced drug targeting: setting novel paradigm in cancer therapeutics
  68. Antitubercular Agents and Tubercular Vaccines in Clinical Trials
  69. Updates on synthesis and biological activities of 1,3,4-oxadiazole: A review
  70. In silico identification of novel antagonists and binding insights by structural and functional analyses of guanylate kinase of Leishmania donovani and interaction with inhibitors
  71. Anticonvulsant activity and neuroprotection assay of 3-substituted-N-aryl-6,7-dimethoxy-3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide analogues
  72. In vivo anti-inflammatory activity and docking study of newly synthesized benzimidazole derivatives bearing oxadiazole and morpholine rings
  73. Synthesis, Biological Evaluation and Molecular Docking Studies of Pyridine Incorporated Chalcone Derivatives as Anticancer Agents
  74. Physicochemical characterization of benzalkonium chloride and urea based deep eutectic solvent (DES): A novel catalyst for the efficient synthesis of isoxazolines under ultrasonic irradiation
  75. ChemInform Abstract: Therapeutic Potential of Coumarins as Antiviral Agents
  76. Therapeutic potential of coumarins as antiviral agents
  77. Rationale Design, Synthesis AndIn VitroAnticancer Activity of New 2,5-Disubstituted-1,3,4-Oxadiazole Analogues
  78. Synthesis and antimicrobial activity of N1-(3-chloro-4-fluorophenyl)-N4-substituted semicarbazone derivatives
  79. Design and synthesis of new 2,5-disubstituted-1,3,4-oxadiazole analogues as anticancer agents
  80. In vitro studies of the antileishmanial activity of the newer 2-(substitutedphenoxy)-N-[(aryl)methylidene]acetohydrazide analogues
  81. Evaluation of Anticancer Activity of Curcumin Analogues Bearing a Heterocyclic Nucleus
  82. Synthesis, antitumor evaluation, and molecular docking studies of indole–indazolyl hydrazide–hydrazone derivatives
  83. Synthesis and Antiproliferative Activity of Some Quinoline and Oxadiazole Derivatives
  84. Synthesis, Anticancer Activity and Molecular Docking Studies of Newer Quinoline Analogues
  85. Synthesis of N-{[5-aryl/alkyl-1,3,4-oxadiazol-2-yl]methyl}pyridin-2-amine as Antimicrobial and Anticancer Agents
  86. Synthesis, antiproliferative activity, and molecular docking studies of curcumin analogues bearing pyrazole ring
  87. Hydrazones as a Privileged Structural Linker in Antitubercular Agents: A Review
  88. Recent advances in the development of vaccines for tuberculosis
  89. Ebola Virus: Current and Future Perspectives
  90. Tuberculosis: Current Treatment, Diagnostics, and Newer Antitubercular Agents in Clinical Trials
  91. Molecular modelling, synthesis, and antimalarial potentials of curcumin analogues containing heterocyclic ring
  92. Synthesis and biological evaluation of 1,3,4-oxadiazole-linked bisindole derivatives as anticancer agents
  93. Design and synthesis of 3-(4-aminophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carboxamide/carbothioamide analogues as antitubercular agents
  94. Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach
  95. Synthesis, characterization and anticancer evaluation of 2-(naphthalen-1-ylmethyl/naphthalen-2-yloxymethyl)-1-[5-(substituted phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-1H-benzimidazole
  96. Simple, efficient, and improved synthesis of Biginelli-type compounds of curcumin as anticancer agents
  97. Synthesis, Anticonvulsant and Neurotoxicity Evaluation of Some Newer N-(2-benzoylbenzofuran-3-yl)-3-(substituted)-propanamide Analogs
  98. Tuberculosis Vaccines: Hopes and Hurdles
  99. Synthesis of 2,5-Disubstituted-1,3,4-oxadiazole Analogs as Novel Anticancer and Antimicrobial Agents
  100. Synthesis and Anticancer Activity ofN-Aryl-5-substituted-1,3,4-oxadiazol-2-amine Analogues
  101. Psychomotor Seizure Test, Neurotoxicity and in vitro Neuroprotection Assay of some Semicarbazone Analogues
  102. Semicarbazone Analogs as Anticonvulsant Agents: A Review
  103. Synthesis of 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6-(substituted phenyl)pyrimidin-2-ol Analogues as Anti-Inflammatory and Analgesic Agents
  104. Synthesis, Characterisation, andIn VitroAnticancer Activity of Curcumin Analogues Bearing Pyrazole/Pyrimidine Ring Targeting EGFR Tyrosine Kinase
  105. Synthesis, Anticancer and Molecular Docking Studies of 2-(4-chlorophenyl)-5-aryl-1,3,4-Oxadiazole Analogues
  106. POMA analyses as new efficient bioinformatics’ platform to predict and optimise bioactivity of synthesized 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  107. Corrigendum to “POMA analyses as new efficient bioinformatics’ platform to predict and optimise bioactivity of synthesized 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues” [Bioorg. Med. Chem. Lett. 22 (2012) 7029–7035]
  108. Synthesis and anticonvulsant evaluation of 2-(substituted benzylidene/ethylidene)-N-(substituted phenyl)hydrazinecarboxamide analogues
  109. Synthesis and Anticancer Activity of 3a,4-dihydro-3H-indeno[1, 2-c]pyrazole-2-carboxamide Analogues
  110. 1,3,4-Oxadiazole: A Biologically Active Scaffold
  111. Molecular Properties Prediction and Synthesis of Novel Pyrazoline Carboxamide Analogs as Antitubercular Agents
  112. Synthesis and Biological Evaluation of N-[2-(substituted-phenyl)-4-oxo-1,3- thiazolidin-3-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide Analogs as Potential Antibacterial and Antifungal Agents
  113. Synthesis and anticonvulsant activity of 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  114. ChemInform Abstract: Synthesis and Antimycobacterial Evaluation of 3a,4-Dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide Analogues.
  115. Discovery of Novel 1,4-Benzodioxane Containing Thiazolidinone Derivatives as Potential Antihepatotoxic Agent
  116. Discovery of novel antitubercular 1,5-dimethyl-2-phenyl-4-([5-(arylamino)-1,3,4-oxadiazol-2-yl]methylamino)-1,2-dihydro-3H-pyrazol-3-one analogues
  117. ChemInform Abstract: Discovery of Novel Antitubercular 3a,4-Dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide Analogues.
  118. Molecular properties prediction and synthesis of novel 1,3,4-oxadiazole analogues as potent antimicrobial and antitubercular agents
  119. Synthesis and antihepatotoxic activity of 5-(2,3-dihydro-1,4-benzodioxane-6-yl)-3-substituted-phenyl-4,5-dihydro-1H-pyrazole derivatives
  120. Synthesis and antimycobacterial evaluation of 3a,4-dihydro-3H-indeno [1,2-c] pyrazole-2-carboxamide analogues
  121. Discovery of novel antitubercular 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
  122. Design, synthesis and antimycobacterial evaluation of novel 3-substituted-N-aryl-6,7-dimethoxy-3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide analogues
  123. ChemInform Abstract: Design, Synthesis and Evaluation of Novel 5,6-Dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4-substituted Phenyl Methanone Analogues.
  124. Synthesis and antimycobacterial evaluation of novel 5,6-dimethoxy-1-oxo-2,5-dihydro-1H-2-indenyl-5,4-substituted phenyl methanone analogues
  125. Design, synthesis and evaluation of novel 5,6-dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4-substituted phenyl methanone analogues