All Stories

  1. Tuberculosis Vaccines: Multidimensional Exploration and Breakthroughs from Innovative Design to Evaluation Systems
  2. Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study...
  3. Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
  4. Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950–2023: a demographic analysis for the Global Burden of Disease Study 2023
  5. CP91110P: A Computationally Designed Multi-Epitope Vaccine Candidate for Tuberculosis via TLR-2/4 Synergistic Immunomodulation
  6. Evaluating H56:IC31 vaccine in tuberculosis recurrence prevention
  7. Diagnostic dilemmas and strain diversity in the MTBVAC phase 1b–2a trial in adults
  8. Application value of nucleic acid MALDI-TOF MS in mycobacterial species identification and drug resistance detection in Mycobacterium tuberculosis
  9. Development and Validation of Early Alert Model for Diabetes Mellitus–Tuberculosis Comorbidity
  10. Bibliometric analysis and knowledge mapping of diabetes mellitus combined with tuberculosis research: trends from 1995 to 2023
  11. Tuberculosis vaccines and therapeutic drug: challenges and future directions
  12. Decoding the WHO Global Tuberculosis Report 2024: A Critical Analysis of Global and Chinese Key Data
  13. Mendelian susceptibility to mycobacterial disease: a rare genetic disorder that demands attention
  14. Leveraging computer-aided design and artificial intelligence to develop a next-generation multi-epitope tuberculosis vaccine candidate
  15. Machine learning model based on SERPING1, C1QB, and C1QC: A novel diagnostic approach for latent tuberculosis infection
  16. Visualization analysis of research progress and trends in coexistence of lung cancer and pulmonary tuberculosis using bibliometrics
  17. WITHDRAWN: Physiological modeling and biomechanical insights of cytokine modulation in COVID-19 and pulmonary fibrosis through a multi-dimensional graph-based approach
  18. Revisiting Bacille Calmette‐Guérin revaccination strategies: timing of immunization, Mycobacterium tuberculosis and non‐tuberculous mycobacteria infections, strain potency and standardization of randomized controlled trials
  19. Construction of novel multi-epitope-based diagnostic biomarker HP16118P and its application in the differential diagnosis of Mycobacterium tuberculosis latent infection
  20. Editorial: Immunological aspects of emerging and re-emerging zoonoses
  21. Impact of diabetes mellitus on tuberculosis prevention, diagnosis, and treatment from an immunologic perspective
  22. Optimising the vaccine strategy of BCG, ChAdOx1 85A, and MVA85A for tuberculosis control
  23. Application of artificial intelligence in diagnosis of pulmonary tuberculosis
  24. Harnessing bioinformatics for the development of a promising multi-epitope vaccine against tuberculosis: The ZL9810L vaccine
  25. Development and Evaluation of a Promising Biomarker for Diagnosis of Latent and Active Tuberculosis Infection
  26. Mycobacterium tuberculosis: immune response, biomarkers, and therapeutic intervention
  27. Research Advances of Tuberculosis Vaccine and its Implication on COVID-19
  28. From immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning
  29. Design and development of a multi‐epitope vaccine for the prevention of latent tuberculosis infection
  30. A comprehensive approach to developing a multi-epitope vaccine against Mycobacterium tuberculosis: from in silico design to in vitro immunization evaluation
  31. Building a model for the differential diagnosis of non-tuberculous mycobacterial lung disease and pulmonary tuberculosis: A case-control study based on immunological and radiological features
  32. Exploring BCG vaccination as a novel approach to prevent recurrent herpes labialis
  33. Immunotherapy and biomarkers in patients with lung cancer with tuberculosis: Recent advances and future Directions
  34. Spatial-temporal patterns and influencing factors for pulmonary tuberculosis transmission in China: an analysis based on 15 years of surveillance data
  35. Next-Generation TB Vaccines: Progress, Challenges, and Prospects
  36. LTBI-negative close contacts of tuberculosis are more likely to develop the disease: enlightenment and lessons from a cluster outbreak
  37. Verapamil Regulates the Macrophage Immunity to Mycobacterium tuberculosis through NF-κB Signaling
  38. Clinical characteristics of patients with non-tuberculous mycobacterial pulmonary disease: a seven-year follow-up study conducted in a certain tertiary hospital in Beijing
  39. Two issues should be noted when designing a clinical trial to evaluate BCG effects on COVID-19
  40. PP19128R, a Multiepitope Vaccine Designed to Prevent Latent Tuberculosis Infection, Induced Immune Responses In Silico and In Vitro Assays
  41. A Summary on Tuberculosis Vaccine Development—Where to Go?
  42. Preventive effects of Mycobacterium tuberculosis DNA vaccines on the mouse model with latent tuberculosis infection
  43. Editorial: Research advances of tuberculosis vaccine and its implication on COVID-19
  44. Corrigendum: Bioinformatics analysis and consistency verification of a novel tuberculosis vaccine candidate HP13138PB
  45. Developing a multiepitope vaccine for the prevention of SARS-CoV-2 and monkeypox virus co-infection: A reverse vaccinology analysis
  46. Research progress on specific and non-specific immune effects of BCG and the possibility of BCG protection against COVID-19
  47. Bioinformatics analysis and consistency verification of a novel tuberculosis vaccine candidate HP13138PB
  48. Immunoinformatic-Based Multi-Epitope Vaccine Design for Co-Infection of Mycobacterium tuberculosis and SARS-CoV-2
  49. Excluding Participants With Mycobacteria Infections From Clinical Trials: A Critical Consideration in Evaluating the Efficacy of BCG Against COVID-19
  50. RNA-seq Analysis of the BCG Vaccine in a Humanized Mouse Model
  51. Evaluation of the consistence between the results of immunoinformatics predictions and real-world animal experiments of a new tuberculosis vaccine MP3RT
  52. Effect of Lymphocyte Subsets on Bone Density in Senile Osteoporosis: A Retrospective Study
  53. CRISPR-Based Diagnostics: A Potential Tool to Address the Diagnostic Challenges of Tuberculosis
  54. Prediction of Th1 and Cytotoxic T Lymphocyte Epitopes of Mycobacterium tuberculosis and Evaluation of Their Potential in the Diagnosis of Tuberculosis in a Mouse Model and in Humans
  55. Endobronchial Valve Treatment of Tuberculous Cavities in Patients with Multidrug-Resistant Pulmonary Tuberculosis: A Randomized Clinical Study
  56. The Natural Effect of BCG Vaccination on COVID-19: The Debate Continues
  57. BCG Vaccination: A potential tool against COVID-19 and COVID-19-like Black Swan incidents
  58. In silico Analysis of Peptide-Based Biomarkers for the Diagnosis and Prevention of Latent Tuberculosis Infection
  59. Child hepatitis of unknown origin may be due to insufficient understanding of adenovirus pathogenicity
  60. Cellular Immunity of Patients with Tuberculosis Combined with Diabetes
  61. SARS-CoV-2 variants and COVID-19 vaccines: Current challenges and future strategies
  62. The Potential Roles of BCG Vaccine in the Prevention or Treatment of COVID-19
  63. Impact of Diabetes Mellitus on the Immunity of Tuberculosis Patients: A Retrospective, Cross-Sectional Study
  64. Clinical Efficacy of a Combination of Thymopentin and Antituberculosis Drugs in Treating Drug-Resistant Pulmonary Tuberculosis: Meta Analysis
  65. Advances in Key Drug Target Identification and New Drug Development for Tuberculosis
  66. Peptide-Based Vaccines for Tuberculosis
  67. The Research Progress in Immunotherapy of Tuberculosis
  68. Differential Diagnosis of Latent Tuberculosis Infection and Active Tuberculosis: A Key to a Successful Tuberculosis Control Strategy
  69. A peptide-based vaccine ACP derived from antigens of Mycobacterium tuberculosis induced Th1 response but failed to enhance the protective efficacy of BCG in mice
  70. Is the tuberculosis vaccine BCG an alternative weapon for developing countries to defeat COVID-19?
  71. Experience and Lessons of Tuberculosis Prevention and Control During COVID-19 Pandemic in Clinic
  72. COVID-19 pandemic: SARS-CoV-2 specific vaccines and challenges, protection via BCG trained immunity, and clinical trials
  73. Comparative study on the antituberculous effect and mechanism of the traditional Chinese medicines NiuBeiXiaoHe extract and JieHeWan
  74. Tuberculosis vaccine BCG: the magical effect of the old vaccine in the fight against the COVID-19 pandemic
  75. Prediction and analyses of HLA‐II restricted Mycobacterium tuberculosis CD4 + T cell epitopes in the Chinese population
  76. Peptides-Based Vaccine MP3RT Induced Protective Immunity Against Mycobacterium Tuberculosis Infection in a Humanized Mouse Model
  77. Exploratory development of PCR-fluorescent probes in rapid detection of mutations associated with extensively drug-resistant tuberculosis
  78. Chinese Traditional Medicine NiuBeiXiaoHe (NBXH) Extracts Have the Function of Antituberculosis and Immune Recovery in BALB/c Mice
  79. Will Mutations in the Spike Protein of SARS-CoV-2 Lead to the Failure of COVID-19 Vaccines?
  80. Dynamic Changes in Chest CT Images Over 167 Days in 11 Patients with COVID-19: A Case Series and Literature Review
  81. Effects of Mycobacterium vaccae vaccine in a mouse model of tuberculosis: protective action and differentially expressed genes
  82. Mannose-binding lectin 2 gene polymorphisms and their association with tuberculosis in a Chinese population
  83. Macrophages enhance mesenchymal stem cell osteogenesis via down-regulation of reactive oxygen species
  84. Animal Models of Tuberculosis Vaccine Research: An Important Component in the Fight against Tuberculosis
  85. Immunogenicity and Therapeutic Effects of Latency-Associated Genes in a Mycobacterium Tuberculosis Reactivation Mouse Model
  86. The current status, challenges, and future developments of new tuberculosis vaccines
  87. Th1 epitope peptides induce protective immunity against Rickettsia rickettsii infection in C3H/HeN mice
  88. An alert of Mycobacterium tuberculosis infection of rhesus macaques in a wild zoo in China
  89. Enhanced Expression of T-Cell Immunoglobulin and Mucin Domain Protein 3 in Endothelial Cells Facilitates Intracellular Killing ofRickettsia heilongjiangensis
  90. Chloroform-Methanol Residue of Coxiella burnetii Markedly Potentiated the Specific Immunoprotection Elicited by a Recombinant Protein Fragment rOmpB-4 Derived from Outer Membrane Protein B of Rickettsia rickettsii in C3H/HeN Mice
  91. Rickettsia rickettsiiouter membrane protein YbgF induces protective immunity in C3H/HeN mice
  92. Enhanced protection against Rickettsia rickettsii infection in C3H/HeN mice by immunization with a combination of a recombinant adhesin rAdr2 and a protein fragment rOmpB-4 derived from outer membrane protein B
  93. Serological characterization of surface-exposed proteins of Coxiella burnetii
  94. Protective immunity against Rickettsia heilongjiangensis in a C3H/HeN mouse model mediated by outer membrane protein B-pulsed dendritic cells
  95. Genomic and comparative genomic analyses of Rickettsia heilongjiangensis provide insight into its evolution and pathogenesis
  96. Identification of Novel Surface-Exposed Proteins of Rickettsia rickettsii by Affinity Purification and Proteomics
  97. Microarray of surface-exposed proteins of rickettsia heilongjiangensisfor serodiagnosis of Far-eastern spotted fever
  98. Surface protein Adr2 of Rickettsia rickettsii induced protective immunity against Rocky Mountain spotted fever in C3H/HeN mice
  99. Exploratory Study on Th1 Epitope-Induced Protective Immunity against Coxiella burnetii Infection
  100. Recombinant protein YbgF induces protective immunity against Rickettsia heilongjiangensis infection in C3H/HeN mice
  101. Proteome Analysis and Serological Characterization of Surface-Exposed Proteins of Rickettsia heilongjiangensis