All Stories

  1. Immunoinformatic Design and Evaluation of a Multi-Epitope mRNA Vaccine RP14914P Targeting Latent Tuberculosis Infection
  2. Identification of biomarkers and construction of discriminating model for tuberculosis patients with diabetes mellitus based on proteomics: a cross-sectional study
  3. Editorial: Community series in research advances of tuberculosis vaccine and its implication on COVID-19, volume III
  4. Clinical characteristics and host factors associated with drug-induced liver injury in 264 pulmonary tuberculosis patients from Hainan province, China
  5. EP9158H: An Immunoinformatics-Designed mRNA Vaccine Encoding Multi-Epitope Antigens and Dual TLR Agonists for Tuberculosis Prevention
  6. HeptaTB Dx: a diagnostic model leveraging cuproptosis-ferroptosis crosstalk for distinguishing latent from active tuberculosis
  7. Tuberculosis Vaccines: Multidimensional Exploration and Breakthroughs from Innovative Design to Evaluation Systems
  8. Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study...
  9. Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
  10. Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950–2023: a demographic analysis for the Global Burden of Disease Study 2023
  11. Global, regional, and national burden of tuberculosis, 1990–2050: a systematic comparative analysis based on retrospective cross-sectional of GBD 2021 and WHO surveillance systems
  12. CP91110P: A Computationally Designed Multi-Epitope Vaccine Candidate for Tuberculosis via TLR-2/4 Synergistic Immunomodulation
  13. Evaluating H56:IC31 vaccine in tuberculosis recurrence prevention
  14. Diagnostic dilemmas and strain diversity in the MTBVAC phase 1b–2a trial in adults
  15. Application value of nucleic acid MALDI-TOF MS in mycobacterial species identification and drug resistance detection in Mycobacterium tuberculosis
  16. Development and Validation of Early Alert Model for Diabetes Mellitus–Tuberculosis Comorbidity
  17. Bibliometric analysis and knowledge mapping of diabetes mellitus combined with tuberculosis research: trends from 1995 to 2023
  18. Tuberculosis vaccines and therapeutic drug: challenges and future directions
  19. Decoding the WHO Global Tuberculosis Report 2024: A Critical Analysis of Global and Chinese Key Data
  20. Mendelian susceptibility to mycobacterial disease: a rare genetic disorder that demands attention
  21. Leveraging computer-aided design and artificial intelligence to develop a next-generation multi-epitope tuberculosis vaccine candidate
  22. Machine learning model based on SERPING1, C1QB, and C1QC: A novel diagnostic approach for latent tuberculosis infection
  23. Visualization analysis of research progress and trends in coexistence of lung cancer and pulmonary tuberculosis using bibliometrics
  24. WITHDRAWN: Physiological modeling and biomechanical insights of cytokine modulation in COVID-19 and pulmonary fibrosis through a multi-dimensional graph-based approach
  25. Revisiting Bacille Calmette‐Guérin revaccination strategies: timing of immunization, Mycobacterium tuberculosis and non‐tuberculous mycobacteria infections, strain potency and standardization of randomized controlled trials
  26. Construction of novel multi-epitope-based diagnostic biomarker HP16118P and its application in the differential diagnosis of Mycobacterium tuberculosis latent infection
  27. Editorial: Immunological aspects of emerging and re-emerging zoonoses
  28. Impact of diabetes mellitus on tuberculosis prevention, diagnosis, and treatment from an immunologic perspective
  29. Optimising the vaccine strategy of BCG, ChAdOx1 85A, and MVA85A for tuberculosis control
  30. Application of artificial intelligence in diagnosis of pulmonary tuberculosis
  31. Harnessing bioinformatics for the development of a promising multi-epitope vaccine against tuberculosis: The ZL9810L vaccine
  32. Development and Evaluation of a Promising Biomarker for Diagnosis of Latent and Active Tuberculosis Infection
  33. Mycobacterium tuberculosis: immune response, biomarkers, and therapeutic intervention
  34. Research Advances of Tuberculosis Vaccine and its Implication on COVID-19
  35. From immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning
  36. Design and development of a multi‐epitope vaccine for the prevention of latent tuberculosis infection
  37. A comprehensive approach to developing a multi-epitope vaccine against Mycobacterium tuberculosis: from in silico design to in vitro immunization evaluation
  38. Building a model for the differential diagnosis of non-tuberculous mycobacterial lung disease and pulmonary tuberculosis: A case-control study based on immunological and radiological features
  39. Exploring BCG vaccination as a novel approach to prevent recurrent herpes labialis
  40. Immunotherapy and biomarkers in patients with lung cancer with tuberculosis: Recent advances and future Directions
  41. Spatial-temporal patterns and influencing factors for pulmonary tuberculosis transmission in China: an analysis based on 15 years of surveillance data
  42. Next-Generation TB Vaccines: Progress, Challenges, and Prospects
  43. LTBI-negative close contacts of tuberculosis are more likely to develop the disease: enlightenment and lessons from a cluster outbreak
  44. Verapamil Regulates the Macrophage Immunity to Mycobacterium tuberculosis through NF-κB Signaling
  45. Clinical characteristics of patients with non-tuberculous mycobacterial pulmonary disease: a seven-year follow-up study conducted in a certain tertiary hospital in Beijing
  46. Two issues should be noted when designing a clinical trial to evaluate BCG effects on COVID-19
  47. PP19128R, a Multiepitope Vaccine Designed to Prevent Latent Tuberculosis Infection, Induced Immune Responses In Silico and In Vitro Assays
  48. A Summary on Tuberculosis Vaccine Development—Where to Go?
  49. Preventive effects of Mycobacterium tuberculosis DNA vaccines on the mouse model with latent tuberculosis infection
  50. Editorial: Research advances of tuberculosis vaccine and its implication on COVID-19
  51. Corrigendum: Bioinformatics analysis and consistency verification of a novel tuberculosis vaccine candidate HP13138PB
  52. Developing a multiepitope vaccine for the prevention of SARS-CoV-2 and monkeypox virus co-infection: A reverse vaccinology analysis
  53. Research progress on specific and non-specific immune effects of BCG and the possibility of BCG protection against COVID-19
  54. Bioinformatics analysis and consistency verification of a novel tuberculosis vaccine candidate HP13138PB
  55. Immunoinformatic-Based Multi-Epitope Vaccine Design for Co-Infection of Mycobacterium tuberculosis and SARS-CoV-2
  56. Excluding Participants With Mycobacteria Infections From Clinical Trials: A Critical Consideration in Evaluating the Efficacy of BCG Against COVID-19
  57. RNA-seq Analysis of the BCG Vaccine in a Humanized Mouse Model
  58. Evaluation of the consistence between the results of immunoinformatics predictions and real-world animal experiments of a new tuberculosis vaccine MP3RT
  59. Effect of Lymphocyte Subsets on Bone Density in Senile Osteoporosis: A Retrospective Study
  60. CRISPR-Based Diagnostics: A Potential Tool to Address the Diagnostic Challenges of Tuberculosis
  61. Prediction of Th1 and Cytotoxic T Lymphocyte Epitopes of Mycobacterium tuberculosis and Evaluation of Their Potential in the Diagnosis of Tuberculosis in a Mouse Model and in Humans
  62. Endobronchial Valve Treatment of Tuberculous Cavities in Patients with Multidrug-Resistant Pulmonary Tuberculosis: A Randomized Clinical Study
  63. The Natural Effect of BCG Vaccination on COVID-19: The Debate Continues
  64. BCG Vaccination: A potential tool against COVID-19 and COVID-19-like Black Swan incidents
  65. In silico Analysis of Peptide-Based Biomarkers for the Diagnosis and Prevention of Latent Tuberculosis Infection
  66. Child hepatitis of unknown origin may be due to insufficient understanding of adenovirus pathogenicity
  67. Cellular Immunity of Patients with Tuberculosis Combined with Diabetes
  68. SARS-CoV-2 variants and COVID-19 vaccines: Current challenges and future strategies
  69. The Potential Roles of BCG Vaccine in the Prevention or Treatment of COVID-19
  70. Impact of Diabetes Mellitus on the Immunity of Tuberculosis Patients: A Retrospective, Cross-Sectional Study
  71. Clinical Efficacy of a Combination of Thymopentin and Antituberculosis Drugs in Treating Drug-Resistant Pulmonary Tuberculosis: Meta Analysis
  72. Advances in Key Drug Target Identification and New Drug Development for Tuberculosis
  73. Peptide-Based Vaccines for Tuberculosis
  74. The Research Progress in Immunotherapy of Tuberculosis
  75. Differential Diagnosis of Latent Tuberculosis Infection and Active Tuberculosis: A Key to a Successful Tuberculosis Control Strategy
  76. A peptide-based vaccine ACP derived from antigens of Mycobacterium tuberculosis induced Th1 response but failed to enhance the protective efficacy of BCG in mice
  77. Is the tuberculosis vaccine BCG an alternative weapon for developing countries to defeat COVID-19?
  78. Experience and Lessons of Tuberculosis Prevention and Control During COVID-19 Pandemic in Clinic
  79. COVID-19 pandemic: SARS-CoV-2 specific vaccines and challenges, protection via BCG trained immunity, and clinical trials
  80. Comparative study on the antituberculous effect and mechanism of the traditional Chinese medicines NiuBeiXiaoHe extract and JieHeWan
  81. Tuberculosis vaccine BCG: the magical effect of the old vaccine in the fight against the COVID-19 pandemic
  82. Prediction and analyses of HLA‐II restricted Mycobacterium tuberculosis CD4 + T cell epitopes in the Chinese population
  83. Peptides-Based Vaccine MP3RT Induced Protective Immunity Against Mycobacterium Tuberculosis Infection in a Humanized Mouse Model
  84. Exploratory development of PCR-fluorescent probes in rapid detection of mutations associated with extensively drug-resistant tuberculosis
  85. Chinese Traditional Medicine NiuBeiXiaoHe (NBXH) Extracts Have the Function of Antituberculosis and Immune Recovery in BALB/c Mice
  86. Will Mutations in the Spike Protein of SARS-CoV-2 Lead to the Failure of COVID-19 Vaccines?
  87. Dynamic Changes in Chest CT Images Over 167 Days in 11 Patients with COVID-19: A Case Series and Literature Review
  88. Effects of Mycobacterium vaccae vaccine in a mouse model of tuberculosis: protective action and differentially expressed genes
  89. Mannose-binding lectin 2 gene polymorphisms and their association with tuberculosis in a Chinese population
  90. Macrophages enhance mesenchymal stem cell osteogenesis via down-regulation of reactive oxygen species
  91. Animal Models of Tuberculosis Vaccine Research: An Important Component in the Fight against Tuberculosis
  92. Immunogenicity and Therapeutic Effects of Latency-Associated Genes in a Mycobacterium Tuberculosis Reactivation Mouse Model
  93. The current status, challenges, and future developments of new tuberculosis vaccines
  94. Th1 epitope peptides induce protective immunity against Rickettsia rickettsii infection in C3H/HeN mice
  95. An alert of Mycobacterium tuberculosis infection of rhesus macaques in a wild zoo in China
  96. Enhanced Expression of T-Cell Immunoglobulin and Mucin Domain Protein 3 in Endothelial Cells Facilitates Intracellular Killing ofRickettsia heilongjiangensis
  97. Chloroform-Methanol Residue of Coxiella burnetii Markedly Potentiated the Specific Immunoprotection Elicited by a Recombinant Protein Fragment rOmpB-4 Derived from Outer Membrane Protein B of Rickettsia rickettsii in C3H/HeN Mice
  98. Rickettsia rickettsiiouter membrane protein YbgF induces protective immunity in C3H/HeN mice
  99. Enhanced protection against Rickettsia rickettsii infection in C3H/HeN mice by immunization with a combination of a recombinant adhesin rAdr2 and a protein fragment rOmpB-4 derived from outer membrane protein B
  100. Serological characterization of surface-exposed proteins of Coxiella burnetii
  101. Protective immunity against Rickettsia heilongjiangensis in a C3H/HeN mouse model mediated by outer membrane protein B-pulsed dendritic cells
  102. Genomic and comparative genomic analyses of Rickettsia heilongjiangensis provide insight into its evolution and pathogenesis
  103. Identification of Novel Surface-Exposed Proteins of Rickettsia rickettsii by Affinity Purification and Proteomics
  104. Microarray of surface-exposed proteins of rickettsia heilongjiangensisfor serodiagnosis of Far-eastern spotted fever
  105. Surface protein Adr2 of Rickettsia rickettsii induced protective immunity against Rocky Mountain spotted fever in C3H/HeN mice
  106. Exploratory Study on Th1 Epitope-Induced Protective Immunity against Coxiella burnetii Infection
  107. Recombinant protein YbgF induces protective immunity against Rickettsia heilongjiangensis infection in C3H/HeN mice
  108. Proteome Analysis and Serological Characterization of Surface-Exposed Proteins of Rickettsia heilongjiangensis