All Stories

  1. HCV genotyping and rational computational designing of an immunogenic multiepitope vaccine against genotype 3a
  2. Development of a Multiple Epitopes‐Based Dengue Vaccine: An Immunoinformatics Approach and Insights From Pakistani Population Genetics
  3. LncRNA HULC and LncRNA HOTAIR expression profile are strong predictors of direct antiviral agents therapy response in chronic Hepatitis C Virus-infected patients
  4. Exploring HPV-linked head and neck cancer in Southern Punjab, Pakistan: Insights from HPV-16 phylogenetic analysis
  5. Polymorphisms in IL-10- and IL-22-Binding Protein Genes as Genetic Predictors of the Direct-Acting Antivirals Treatment Response in Patients with Chronic Hepatitis C Virus
  6. Mammalian Cell Expression of a Fully Functional Recombinant E6 Protein Encoded by HPV16 Isolate from Pakistani Population
  7. Phylogenetic Analysis of E6 and E7 Gene of Human Papillomavirus 16 Variants Isolated from Pakistani Population
  8. The emerging role of epigenetics (DNA methylation) in hepatitis C virus-induced hepatocellular carcinoma
  9. Molecular epidemiology and genetic characterization of hepatitis B virus in two major provinces of Pakistan
  10. Computational prediction of a phage cocktail active against multidrug-resistant bacteria
  11. Coincidence of HCV and chronic kidney disease-a systematic review and meta-analysis
  12. The Factors Associated With Mutant Epidermal Growth Factor Receptor Positivity in Patients With Lung Cancer: A Study From a Tertiary Care Center in Pakistan
  13. Regulatory pathways and therapeutic potential of PDE4 in liver pathophysiology
  14. Improving Access to Anti-HDV Testing: Development and Validation of an Affordable In-House ELISA Assay
  15. Exploring the Concordance Between High-Risk Human Papillomavirus Infections in Cervical and Oral Sites Among Females: A Cross-Sectional Study in Punjab, Pakistan
  16. Assessment of ubiquitin specific Peptidase-18 gene in peripheral blood of chronic hepatitis C patients treated with direct-acting antiviral drugs
  17. A Comparative Analysis of Baseline Variables in Responder and Non-Responder Groups of Chronic Hepatitis C patients
  18. Potential Role of Recombinant Capsid Protein of Dengue Virus Serotype 2 in the Development of an In-House Elisa Based Detection of Infection
  19. Quasispecies Analysis Through NGS and Identification of Escape Mutation in a Family Infected with Hepatitis B Virus: A Study from Lahore, Pakistan
  20. An ncRNA transcriptomics-based approach to design siRNA molecules against SARS-CoV-2 double membrane vesicle formation and accessory genes
  21. Whole-genome analysis and evolutionary characterization of cervical and oral human papillomavirus 16
  22. Harnessing Nature’s Gifts:Salix nigraand Its Potential for Combating Hepatitis C Virus (HCV)
  23. Seroprevalence of SARS-CoV-2: Insights into the epidemiology of the pandemic
  24. Expression Profiling of the Tripartite Motif Family Genes in Chronic Hepatitis C Patients
  25. Risk of adverse outcomes following treatment with direct acting antiviral drugs in HCV infected patients with liver cirrhosis
  26. Transcriptional Analysis of TP53 Gene in Chronic Hepatitis C Patients Treated with Sofosbuvir, Daclatasvir, Pegylated Interferon, and Ribavirin
  27. Structural Analysis and Epitope Prediction of S2 Domain of SARS-CoV-2, Conservation Analysis Among Major Variants
  28. The History and Current Killings of Polio Vaccinators in Pakistan: A Need for Targeted Surveillance Strategy
  29. Genotypic distribution of human papillomavirus and phylogenetic analysis of E6 and E7 gene of HR-HPV variants isolated from Pakistani population
  30. Frequency of Hepatitis D Viral Infection in Chronic Hepatitis B Patients in Pakistan
  31. Identification of Predictive Factors in Chronic Hepatitis C Patients with Non-Infected Individuals: A Comparative Analysis
  32. Methanolic Extract of Neem Plant Inhibits NS3 and NS5A Nonstructural Proteins of HCV 3A Genotype
  33. An Immunoinformatics Approach to Design a Potent Multi-Epitope Vaccine against Asia-1 Genotype of Crimean–Congo Haemorrhagic Fever Virus Using the Structural Glycoproteins as a Target
  34. A review on hepatitis C virus: role of viral and host-cellular factors in replication and existing therapeutic strategies
  35. Adenovirus Vector System: Construction, History and Therapeutic Applications
  36. Molecular characterization of recombinant premembrane protein of dengue virus serotype‐2 for development of diagnostic assay
  37. Hepatitis C virus transmission cluster among injection drug users in Pakistan
  38. Molecular characterization and risk factors of oral high‐risk human papillomavirus among females in Punjab, Pakistan
  39. P2X4 receptors mediate induction of antioxidants, fibrogenic cytokines and ECM transcripts; in presence of replicating HCV in in vitro setting: An insight into role of P2X4 in fibrosis
  40. Immune-related therapeutics: an update on antiviral drugs and vaccines to tackle the COVID-19 pandemic
  41. A review on corona virus pandemic: Update on epidemiology, diagnosis, and treatment
  42. Insights into the Structure, Replication, and Pathogenesis of the Severe Acute Respiratory Syndrome Coronavirus 2
  43. Bacterial Expression and Purification of Antigenic Recombinant Protein Encoded by Hepatitis Delta Virus Antigen of Pakistani Isolate
  44. Patient with Suspected COVID-19 Infection Tests Negative in Nasopharyngeal Swabs but is Confirmed by Laboratory Tests and Chest CT Scan: A Case Report
  45. Current Status of Therapeutic Approaches and Vaccines for SARS-CoV-2
  46. Next-generation sequencing studies on the E1-HVR1 region of hepatitis C virus (HCV) from non-high-risk HCV patients living in Punjab and Khyber Pakhtunkhwa, Pakistan
  47. Cytokine storm syndrome in SARS-CoV-2: a review
  48. Early detection of MDR Mycobacterium tuberculosis mutations in Pakistan
  49. Distribution of High-risk Human Papillomavirus Genotypes in Cervical Secretions in Punjab
  50. MMTV-LIKE virus and c-myc over-expression are associated with invasive breast cancer
  51. Seroprevalence of SARS-CoV-2 in Pakistan: an update on epidemiological trends
  52. CRISPR-Cas13a mediated targeting of hepatitis C virus internal-ribosomal entry site (IRES) as an effective antiviral strategy
  53. Identification and expression analysis of antigenic sites of hepatitis C virus genotype 3a NS3 and NS5A genes of local isolate
  54. p53 and rb Promoter Methylation in Hepatitis C virus-related Chronic Hepatitis and Hepatocellular Carcinoma
  55. Dengue Vaccines: Ongoing Challenges and Current Status in the Advancement of Different Candidates
  56. Novel Coronavirus: A Review from Origin to Current Status of Therapeutic Strategies
  57. Genome‐wide methylation profiling of HCV pathogenesis to develop diabetes and diabetic complications
  58. Association of dupA, iceA, homB Genes of Helicobacter pylori with Gastritis, Peptic Ulcer Disease and Gastric Cancer
  59. Peripheral Expression ofCXCL10Gene in Chronic Hepatitis C Patients Treated with Sofosbuvir, Daclatasvir, and Ribavirin
  60. Comparing the risk of hypothyroidism in HCV patients treated with different DAA drugs combinations (sofosbuvir + interferon + ribavirin and sofosbuvir + daclatasvir + ribavirin)
  61. Blood-based gene expression profile of oxidative stress and antioxidant genes for identifying surrogate markers of liver tissue injury in chronic hepatitis C patients
  62. Applications and hazards associated with carbon nanotubes in biomedical sciences
  63. Advancements in Developing an Effective and Preventive Dengue Vaccine
  64. Expression of TRIM22 mRNA in chronic hepatitis C patients treated with direct‐acting antiviral drugs
  65. Association of Interleukin 28B Polymorphism with Clearance of Hepatitis C Virus: A Mini Review
  66. Cervical cancer vaccination awareness and acceptance among the females of Punjab, Pakistan
  67. Drug Resistance in Hepatitis C Virus: Future Prospects and Strategies to Combat It
  68. Paradoxical Role of Dengue Virus Envelope Protein Domain III Antibodies in Dengue Virus Infection
  69. Prevalence and Upcoming Threats of Chikungunya Virus in Pakistani Population
  70. Role of MicroRNAs in Establishing Latency of Human Immunodeficiency Virus
  71. Herpes Simplex Virus Type 1 and Host Antiviral Immune Responses: An Update
  72. A novel avian isolate of hepatitis E virus from Pakistan
  73. Characterization of Hepatitis Delta Virus Among Pregnant Women of Pakistan
  74. Sequence Variability of HCV 3a Isolates Based On Core Gene in Patients From Lahore, Pakistan
  75. Cosmopolitan A1 lineage of dengue virus serotype 2 is circulating in Pakistan: A study from 2017 dengue viral outbreak
  76. Scoping Review of Crimean-Congo Hemorrhagic Fever (CCHF) Literature and Implications of Future Research
  77. In silico structural elucidation of RNA-dependent RNA polymerase towards the identification of potential Crimean-Congo Hemorrhagic Fever Virus inhibitors
  78. Advances in the role of HCV nonstructural protein 5a (NS5A) of 3a genotype in inducing insulin resistance by possible phosphorylation of AKT/PKB
  79. Short article: Hepatitis C and G virus coinfection in Punjab, Pakistan: incidence and its correlation analysis with clinical data
  80. The interplay between viruses and TRIM family proteins
  81. Comparative Analysis of Immunological and Genomic Outcomes of Dengue Virus Outbreak in Pakistan
  82. HSV-1 Infection: Role of Viral Proteins and Cellular Receptors
  83. Molecular Detection of Hepatitis E Virus in Layer Chickens: A Possible Public Health Risk in Pakistan
  84. Antigenic Peptide Prediction From E6 and E7 Oncoproteins of HPV Types 16 and 18 for Therapeutic Vaccine Design Using Immunoinformatics and MD Simulation Analysis
  85. Evolution of efficacious pangenotypic hepatitis C virus therapies
  86. Complete Genome Amplification and Sequencing of DENV-2 Pakistani Isolates: Analysis Reveals Molecular Evolution of DENV-2
  87. Recent trends in molecular epidemiology of Hepatitis C virus in Mardan, KPK Pakistan
  88. Perspectives towards antiviral drug discovery against Ebola virus
  89. Genetic diversity of Hepatitis C Virus in Pakistan using Next Generation Sequencing
  90. Prevalence of thyroid stimulating hormone dysfunction among sofosbuvir‐treated HCV‐infected patients: A real‐world clinical experience
  91. Tattooing trend: major cause of HCV transmission among youngsters
  92. Molecular epidemiology of hepatitis delta and hepatitis B viruses circulating in two major provinces (East and North-West) of Pakistan
  93. Biomarkers for diagnosis of pre-eclampsia and endometriosis
  94. An Overview of Cancer Immunotherapeutic Strategies
  95. Poor glycemic control and abrupt onset of diabetes in HCV patients receiving direct-acting antiviral drugs: case series
  96. Unexpected Response Profiles Seen in Hepatitis C Virus-Infected Patients Treated with Sofosbuvir Plus Ribavirin: Five Case Reports
  97. Study of promoter hypomethylation profiles of RAS oncogenes in hepatocellular carcinoma derived from hepatitis C virus genotype 3a in Pakistani population
  98. Poor response to direct-acting antiviral therapy in HCV-infected elderly population: a real-life cohort study based on GeneXpert® technology
  99. Explosive Rise in Viral Infections Through Meat-Sellers
  100. Expression of SOCS1 and SOCS3 Genes in Interferon-Treated and Direct-Acting Antiviral Drugs-Treated Hepatitis C Patients
  101. Role of altered immune cells in liver diseases: a review
  102. Successful treatment of HCV/TB co-infected patient with sofosbuvir and daclatasvir: a case report
  103. Calculation of Wiener Indices of Thiazolides: The Potent Inhibitors of Hepatitis B Virus and Hepatitis C Virus Replication
  104. An Increase in Expression of SOCS1 Gene with Increase in Hepatitis C Virus Viral Load
  105. An updated systematic review of Zika virus-linked complications
  106. Zika virus: Is Pakistan next?
  107. Polymerase Chain Reaction-Based Detection Method Is Suitable for Dengue Infection During Epidemics
  108. Role of circulatory microRNAs in the pathogenesis of hepatitis C virus
  109. Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions
  110. Thirty years of HIV in Pakistan: a systematic review of prevalence and current scenario
  111. Current status of therapeutic and vaccine approaches against Zika virus
  112. Therapeutic Strategies of Clustered Regularly Interspaced Palindromic Repeats-Cas Systems for Different Viral Infections
  113. Molecular detection of Isoniazid, Rifampin and Ethambutol resistance to M. tuberculosis and M. bovis in multidrug resistant tuberculosis (MDR-TB) patients in Pakistan
  114. Prevalence of hepatitis-C virus genotypes and potential transmission risks in Malakand Khyber Pakhtunkhwa, Pakistan
  115. Rising relapse rate in hepatitis C virus type 3a-infected patients against sofosbuvir and ribavirin combination therapy: a Pakistani experience
  116. Evaluation of three techniques for detection of IL28B SNP: A prognostic tool for HCV treatment outcome
  117. Emerging Viral Infections in Pakistan: Issues, Concerns, and Future Prospects
  118. Prevalence and Molecular Detection of Dengue Virus in 2013 Outbreak in KPK and Punjab, Pakistan
  119. Forensic applications of Y chromosomal properties
  120. Global expansion of chikungunya virus: mapping the 64-year history
  121. Advances in research on Zika virus
  122. Causes of deafness in the Punjab region of Pakistan and the role of consanguinity
  123. HCV-induced regulatory alterations of IL-1β, IL-6, TNF-α, and IFN-ϒ operative, leading liver en-route to non-alcoholic steatohepatitis
  124. Study of inhibition of interferon inducible genes by dephosphorylation of E2 envelope gene of HCV genotype 1a
  125. Aedes aegypti is the Major Vector for Transmission of Dengue Virus in Lahore, Pakistan
  126. A systematic review of treatment response rates in Pakistani hepatitis C virus patients; current prospects and future challenges
  127. Towards peptide vaccines against Zika virus: Immunoinformatics combined with molecular dynamics simulations to predict antigenic epitopes of Zika viral proteins
  128. Immunotherapeutic strategies for sexually transmitted viral infections: HIV, HSV and HPV
  129. Influence of Hepatitis B Virus Genetic Heterogeneity on Treatment Response Against Lamivudine and Interferon in Pakistani Isolates
  130. Circulating serotypes of dengue virus and their incursion into non-endemic areas of Pakistan; a serious threat
  131. Detection of Anti-Hepatitis B Virus Drug Resistance Mutations Based on Multicolor Melting Curve Analysis
  132. Zika: As an emergent epidemic
  133. Construction of Mammalian Expression Vector of Core Gene of HCV of Pakistani Isolate Genotype 1a
  134. Genetic distribution of 15 autosomal STR markers in the Punjabi population of Pakistan
  135. Parallel expression profiling of hepatic and serum microRNA-122 associated with clinical features and treatment responses in chronic hepatitis C patients
  136. Complete genome sequencing and comparative analysis of three dengue virus type 2 Pakistani isolates
  137. Introduction and evolution of dengue virus type 2 in Pakistan: a phylogeographic analysis
  138. Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Marburg virus evolution
  139. Deep sequencing shows microRNA expression in hepatitis C patients is associated with the end treatment response
  140. Phylogenetic and 2D/3D Analysis of HCV 1a NS4A Gene/Protein in Pakistani Isolates
  141. The genotype CC ofIL-28B SNP rs12979860 is significantly associated with a sustained virological response in chronic HCV-infected Pakistani patients
  142. Expression of Hepatitis C Virus Core and E2 antigenic recombinant proteins and their use for development of diagnostic assays
  143. P0701 : Next generation sequencing reveals differential expression profiles of hepatic micrornas in chronic hepatitis C patients
  144. Computational Prediction and Analysis of Envelop Glycoprotein Epitopes of DENV-2 and DENV-3 Pakistani Isolates: A First Step towards Dengue Vaccine Development
  145. Evidence-based consensus on the diagnosis, prevention and management of hepatitis C virus disease
  146. Genetic history of hepatitis C virus in Pakistan
  147. Studies on the role of NS3 and NS5A non-structural genes of hepatitis C virus genotype 3a local isolates in apoptosis
  148. Prevalence and Molecular Determination of Hepatitis C Infection in Khyber Pakhtunkhwa, Pakistan
  149. Correlation of biochemical markers and HCV RNA titers with fibrosis stages and grades in chronic HCV-3a patients
  150. Hepatitis delta virus genotype-1 alone cocirculates with hepatitis B virus genotypes A and D in Pakistan
  151. Studies on the role of neutralizing antibodies against envelope genes in resolving HCV pseudo-particles infection
  152. Generation of infectious HCV pseudo typed particles and its utilization for studying the role of CD81 & SRBI receptors in HCV infection
  153. Emergence of genetically variant Hepatitis C virus population in response to increased antiviral drug pressure, Pakistan
  154. Determination of hepatitis C virus genotypes circulating in different districts of Punjab (Pakistan)
  155. Inhibitory effect of kaolin minerals compound against hepatitis C virus in Huh-7 cell lines
  156. De Novo modeling of Envelope 2 protein of HCV isolated from Pakistani patient and epitopes prediction for vaccine development
  157. Change in demographic pattern of dengue virus infection: evidence from 2011 dengue outbreak in Punjab, Pakistan
  158. Tourism–growth nexus in Pakistan: Evidence from ARDL bounds tests
  159. Seroepidemiology of dengue fever in Khyber Pakhtunkhawa, Pakistan
  160. The first complete genome sequence of HCV-1a from Pakistan and a phylogenetic analysis with complete genomes from the rest of the world
  161. Mutations in the NS5A gene are associated with response to interferon+ribavirin combination therapy in patients with chronic hepatitis C virus 3a infection
  162. Prevalence of HBV infection in suspected population of conflict-affected area of war against terrorism in North Waziristan FATA Pakistan
  163. Computational identification of interplay between phosphorylation and O-β-glycosylation of human occludin as potential mechanism to impair hepatitis C virus entry
  164. Hepatitis E virus-associated aplastic anaemia: The first case of its kind
  165. Computational Identification and Modeling of Crosstalk between Phosphorylation, O-β-glycosylation and Methylation of FoxO3 and Implications for Cancer Therapeutics
  166. Association of Hepatitis C Virus With Insulin Resistance: Evidences From Animal Studies and Clinical Studies
  167. Mycoplasma genitalium: A comparative genomics study of metabolic pathways for the identification of drug and vaccine targets
  168. PCR could be a method of choice for identification of both pulmonary and extra-pulmonary tuberculosis
  169. High baseline interleukine-8 level is an Independent risk factor for the achievement of sustained virological response in chronic HCV patients
  170. Mixed Genotype Infections with Hepatitis C Virus, Pakistan
  171. An overview of Triple infection with Hepatitis B, C and D viruses
  172. Expression of core antigen of HCV genotype 3a and its evaluation as screening agent for HCV infection in Pakistan
  173. The prevalence of HBV infection in the cohort of IDPs of war against terrorism in Malakand Division of Northern Pakistan
  174. Evaluation of three different hepatitis C virus typing methods for detection of mixed-genotype infections
  175. Occult hepatitis C virus infection and associated predictive factors: The Pakistan experience
  176. Envelope 2 protein phosphorylation sites S75 & 277 of hepatitis C virus genotype 1a and interferon resistance: A sequence alignment approach
  177. Promiscuous prediction and conservancy analysis of CTL binding epitopes of HCV 3a viral proteome from Punjab Pakistan: an In Silico Approach
  178. An overview of treatment response rates to various anti-viral drugs in Pakistani Hepatitis B Virus infected patients
  179. Change in hepatitis C virus clades: A cross-sectional study of chronic HCV patients in Pakistan from 2000–2010
  180. Isolation and characterization of two new hepatitis E virus genotype 1 strains from two mini-outbreaks in Lahore, Pakistan
  181. Hepatitis G Virus associated aplastic anemia: A recent case from Pakistan
  182. Oncogenic potential of Human Papillomavirus (HPV) and its relation with cervical cancer
  183. True prevalence of twin HDV-HBV infection in Pakistan: a molecular approach
  184. Positional effect of phosphorylation sites 266 and 267 in the cytoplasmic domain of the E2 protein of hepatitis C virus 3a genotype: Interferon Resistance analysis via Sequence Alignment
  185. Hepatitis C virus genotypes circulating in district Swat of Khyber Pakhtoonkhaw, Pakistan
  186. Determination of HCV genotypes and viral loads in chronic HCV infected patients of Hazara Pakistan
  187. Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan
  188. Characterization of Hepatitis C Virus genotype 3a Hypervariable region 1 in patients achieved rapid virological response to alpha interferon and Ribavirin Combination therapy
  189. Hepatitis B virus in Pakistan: A systematic review of prevalence, risk factors, awareness status and genotypes
  190. Establishment of stable Huh-7 cell lines expressing various hepatitis C virus genotype 3a protein: an in-vitro testing system for novel anti-HCV drugs
  191. Effects of Host and virus related factors on Interferon-α+ribavirin and Pegylated-interferon+ribavirin treatment outcomes in Chronic Hepatitis C patients
  192. Hepatitis Associated Aplastic Anemia: A review
  193. Serotype and genotype analysis of dengue virus by sequencing followed by phylogenetic analysis using samples from three mini outbreaks-2007-2009 in Pakistan
  194. Response to combination therapy of HCV 3a infected Pakistani patients and the role of NS5A protein
  195. Identification of ionotrophic purinergic receptors in Huh-7 cells and their response towards structural proteins of HCV genotype 3a
  196. Pattern and molecular epidemiology of Hepatitis B virus genotypes circulating in Pakistan
  197. The changing epidemiology pattern and frequency distribution of hepatitis C virus in Pakistan
  198. Simultaneous Amplification of Two Bacterial Genes: More Reliable Method of Helicobacter pylori Detection in Microbial Rich Dental Plaque Samples
  199. Prevalence of active hepatitis c virus infection in district mansehra pakistan
  200. Molecular epidemiology of Hepatitis C virus genotypes in Khyber Pakhtoonkhaw of Pakistan
  201. Prevalence of hepatitis delta virus infection among hepatitis b virus surface antigen positive patients circulating in the largest province of pakistan
  202. Mutations in the E2-PePHD region of hepatitis C virus genotype-3a and correlation with response to interferon and ribavirin combination therapy in Pakistani patients
  203. Hepatitis C Treatment: current and future perspectives
  204. Avian influenza A (H9N2): computational molecular analysis and phylogenetic characterization of viral surface proteins isolated between 1997 and 2009 from the human population
  205. Nucleotide identity and variability among different Pakistani hepatitis C virus isolates
  206. A study of best positive predictors for sustained virologic response to interferon alpha plus ribavirin therapy in naive chronic hepatitis C patients
  207. Hepatitis C virus genotype 3a infection and hepatocellular carcinoma: Pakistan experience
  208. Development of an improved genotyping assay for the detection of hepatitis C virus genotypes and subtypes in Pakistan
  209. Frequency distribution of hepatitis C virus genotypes in different geographical regions of Pakistan and their possible routes of transmission
  210. High prevalence of hepatitis C virus infection in the largest province of Pakistan