All Stories

  1. The Effect of 2′F-RNA on I-Motif Structure and Stability
  2. Resolution of complex mixtures of duplex and antiparallel triplex DNA structures by capillary electrophoresis and multivariate analysis
  3. Unraveling the Amplification-Free Quantitative Detection of Viral RNA in Nasopharyngeal Swab Samples Using a Compact Electrochemical Rapid Test Device
  4. Modified Bis-pyrimidine Clamps for Triplex Formation and Their Use in SARS-CoV-2 Detection
  5. Targeted Tumor Microenvironment Delivery of Floxuridine Prodrug via Soluble Silica Nanoparticles in Malignant Melanoma as a Model for Aggressive Cancer Treatment
  6. On the interaction of anticancer G-quadruplex ligands with GalNAc-functionalized G-quadruplex-forming carriers for selective recognition and treatment of hepatocellular carcinoma
  7. Targeted Tumor Microenvironment Delivery of Floxuridine ProdrugviaSoluble Silica Nanoparticles in Malignant Melanoma as a Model for Aggressive Cancer Treatment
  8. Assessment of methodologies based on the formation of antiparallel triplex DNA structures and fluorescent silver nanoclusters for the detection of pyrimidine-rich sequences
  9. Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism
  10. Manual and automated synthesis of modified oligonucleotides on core–shell solid supports
  11. Aptamer-Hytac Chimeras for Targeted Degradation of SARS-CoV-2 Spike-1
  12. Polypurine Reverse Hoogsteen hairpins as a therapeutic tool for SARS-CoV-2 infection
  13. Surface decoration of PLGA nanoparticles enables efficient transport of floxuridine oligomers into mammalian cells
  14. The synthesis of solid supports carrying base labile linkers to generate 3′-phosphate oligonucleotides
  15. DNA-directed immobilization fluorescent immunoarray for multiplexed antibiotic residue determination in milk
  16. Engineering ternary systems as non-viral vehicles for transporting floxuridine oligomer
  17. Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives
  18. Biophysical evaluation of antiparallel triplexes for biosensing and biomedical applications
  19. Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration
  20. Single‐Step Functionalization Strategy of Graphene Microtransistor Array with Chemically Modified Aptamers for Biosensing Applications
  21. Synthesis and Evaluation of 3′-Oleyl–Oligonucleotide Conjugates as Potential Cellular Uptake Enhancers
  22. Synthesis of 2′-O-Methyl/2′-O-MOE-L-Nucleoside Derivatives and Their Applications: Preparation of G-Quadruplexes, Their Characterization, and Stability Studies
  23. Special Issue “Frontiers in Nucleic Acid Chemistry—In Memory of Professor Enrique Pedroso for His Outstanding Contributions to Nucleic Acid Chemistry”
  24. Rapid and Highly Efficient Separation of i-Motif DNA Species by CE-UV and Multivariate Curve Resolution
  25. Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs)
  26. Detection of pyrimidine-rich DNA sequences based on the formation of parallel and antiparallel triplex DNA and fluorescent silver nanoclusters
  27. Exploring the stabilizing effect on the i-motif of neighboring structural motifs and drugs
  28. Stability of polymeric cationic niosomes and their plasmid DNA-based complexes as gene delivery carriers
  29. Evaluation of Poly(N-Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells
  30. Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs
  31. Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies
  32. Correction: Clua et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules 2022, 27, 3944
  33. Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)
  34. Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region
  35. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes
  36. Cover Picture: Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications (Chem. Rec. 4/2022)
  37. A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model
  38. Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications
  39. Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency
  40. Investigation of the Complexes Formed between PARP1 Inhibitors and PARP1 G-Quadruplex at the Gene Promoter Region
  41. Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines
  42. Biodistribution of 68/67Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging
  43. Exploring the Interaction of Curaxin CBL0137 with G-Quadruplex DNA Oligomers
  44. The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis
  45. Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake
  46. Structural Effects of Incorporation of 2'‐Deoxy‐2'2'‐Difluorodeoxycytidine (Gemcitabine) in A‐ and B‐Form Duplexes
  47. Parallel G-quadruplex Structures Increase Cellular Uptake and Cytotoxicity of 5-Fluoro-2′-deoxyuridine Oligomers in 5-Fluorouracil Resistant Cells
  48. Biomedical Applications of DNA-nanostructures
  49. EcoRII Restriction Endonuclease Forms Specific Contacts to the Bases of Its Target Sequence Flipped from DNA in a Transition Complex with Photoactivatable Substrates
  50. G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide
  51. Oligonucleotides Containing 1-Aminomethyl or 1-Mercaptomethyl-2-deoxy-d-ribofuranoses: Synthesis, Purification, Characterization, and Conjugation with Fluorophores and Lipids
  52. Nanoparticles for Brain Drug Delivery
  53. Nucleic Acids Chemistry
  54. Preparation of Lipid-Conjugated siRNA Oligonucleotides for Enhanced Gene Inhibition in Mammalian Cells
  55. Studies on the interactions of Ag(i) with DNA and their implication on the DNA-templated synthesis of silver nanoclusters and on the interaction with complementary DNA and RNA sequences
  56. Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles
  57. Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery
  58. Developing Protein–Antitumoral Drug Nanoconjugates as Bifunctional Antimicrobial Agents
  59. Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples
  60. Study of alkaloid berberine and its interaction with the human telomeric i-motif DNA structure
  61. Sorting hidden patterns in nanoparticle performance for glioblastoma using machine learning algorithms
  62. Non-viral mediated gene therapy in human cystic fibrosis airway epithelial cells recovers chloride channel functionality
  63. Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter region of the SMARCA4 gene
  64. Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins
  65. Fast and Accurate Pneumocystis Pneumonia Diagnosis in Human Samples Using a Label-Free Plasmonic Biosensor
  66. Brain Angiogenesis Induced by Nonviral Gene Therapy with Potential Therapeutic Benefits for Central Nervous System Diseases
  67. Niosome-Based Approach for In Situ Gene Delivery to Retina and Brain Cortex as Immune-Privileged Tissues
  68. Ethylcellulose nanoparticles as a new “in vitro” transfection tool for antisense oligonucleotide delivery
  69. Sulfonamide as amide isostere for fine-tuning the gelation properties of physical gels
  70. Liposomes‐ in ‐Chitosan Hydrogels: Challenges and Opportunities for Biomedical Applications
  71. Alginate Hydrogels as Scaffolds and Delivery Systems to Repair the Damaged Spinal Cord
  72. A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor
  73. Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41
  74. Aptamer-peptide conjugates as a new strategy to modulate human α-thrombin binding affinity
  75. Cationic niosome-based hBMP7 gene transfection of neuronal precursor NT2 cells to reduce the migration of glioma cells in vitro
  76. Study of conformational transitions of i-motif DNA using time-resolved fluorescence and multivariate analysis methods
  77. Gene delivery to the rat retina by non-viral vectors based on chloroquine-containing cationic niosomes
  78. The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry
  79. Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
  80. On the Race for More Stretchable and Tough Hydrogels
  81. Parallel Clamps and Polypurine Hairpins (PPRH) for Gene Silencing and Triplex‐Affinity Capture: Design, Synthesis, and Use
  82. Efficient bioactive oligonucleotide‐protein conjugation for cell‐targeted cancer therapy
  83. Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
  84. Expanding the limits of amide–triazole isosteric substitution in bisamide-based physical gels
  85. Overview of DNA Self-Assembling: Progresses in Biomedical Applications
  86. Detection of a microRNA involved in human disease
  87. Detection of DNA methylation
  88. Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles
  89. Synthesis of Oligonucleotides Carrying Nucleic Acid Derivatives of Biomedical and Structural Interest
  90. Successful evaluation of a nanodrug against metastasis
  91. Preparation of new compounds with interesting porperties in biomedicine
  92. siRNA Modified with 2′-Deoxy-2′-C -methylpyrimidine Nucleosides
  93. Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques
  94. Synthesis, Characterization, and Self-Assembly of a Tetrathiafulvalene (TTF)–Triglycyl Derivative
  95. Isosteric Substitution of 4H-1,2,4-Triazole by 1H-1,2,3-Triazole in Isophthalic Derivative Enabled Hydrogel Formation for Controlled Drug Delivery
  96. Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates
  97. Stem cell-based gene delivery mediated by cationic niosomes for bone regeneration
  98. Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study
  99. DNA-based nanoscaffolds as vehicles for 5-fluoro-2′-deoxyuridine oligomers in colorectal cancer therapy
  100. Electrochemical and AFM Characterization of G-Quadruplex Electrochemical Biosensors and Applications
  101. Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
  102. Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes
  103. Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling
  104. AS1411-decorated niosomes as effective nanocarriers for Ru(iii)-based drugs in anticancer strategies
  105. Lipid-Oligonucleotide Conjugates Forming G-Quadruplexes (Lipoquads) as Potent Inhibitors of HIV Entry
  106. i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene
  107. DNA-Origami-Aided Lithography for Sub-10 Nanometer Pattern Printing
  108. Biochemistry of RNA Silencing
  109. Cover Picture: Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues (ChemBioChem 12/2017)
  110. Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties
  111. Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues
  112. The effect of l -thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures
  113. Erratum: Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
  114. Antiviral activity of lipid-DNA molecules
  115. DNA-Origami-Driven Lithography for Patterning on Gold Surfaces with Sub-10 nm Resolution
  116. Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels
  117. Cationic nioplexes-in-polysaccharide-based hydrogels as versatile biodegradable hybrid materials to deliver nucleic acids
  118. Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms
  119. The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biological properties of oligonucleotides
  120. Meet Our Editorial Board Member
  121. Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA
  122. Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
  123. The role of helper lipids in the intracellular disposition and transfection efficiency of niosome formulations for gene delivery to retinal pigment epithelial cells
  124. The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA
  125. siRNA and RNAi optimization
  126. The influence of the polar head-group of synthetic cationic lipids on the transfection efficiency mediated by niosomes in rat retina and brain
  127. Biodegradable liposome-encapsulated hydrogels for biomedical applications: a marriage of convenience
  128. Cellular uptake studies of antisense oligonucleotides using G-quadruplex-nanostructures. The effect of cationic residue on the biophysical and biological properties
  129. Nioplexes encapsulated in supramolecular hybrid biohydrogels as versatile delivery platforms for nucleic acids
  130. Understanding the effect of the nature of the nucleobase in the loops on the stability of the i-motif structure
  131. Label-free electrochemical DNA sensor using “click”-functionalized PEDOT electrodes
  132. Sensitive and label-free detection of miRNA-145 by triplex formation
  133. Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers
  134. 1-[2,3-Bis(tetradecyloxy)propyl]-3-[2-(piperazin-1-yl)ethyl]urea
  135. New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
  136. Synthesis of oligonucleotides carrying fluorescently labelled O6-alkylguanine for measuring hAGT activity
  137. RNA modified with acyclic threoninol nucleic acids for RNA interference
  138. Protamine/DNA/Niosome Ternary Nonviral Vectors for Gene Delivery to the Retina: The Role of Protamine
  139. Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences
  140. Modulation of the RNA Interference Activity Using Central Mismatched siRNAs and Acyclic Threoninol Nucleic Acids (aTNA) Units
  141. Glucose Conjugation of Anti-HIV-1 Oligonucleotides Containing Unmethylated CpG Motifs Reduces Their Immunostimulatory Activity
  142. Niosomes based on synthetic cationic lipids for gene delivery: the influence of polar head-groups on the transfection efficiency in HEK-293, ARPE-19 and MSC-D1 cells
  143. Novel non-viral gene delivery systems composed of carbosilane dendron functionalized nanoparticles prepared from nano-emulsions as non-viral carriers for antisense oligonucleotides
  144. The effect of a cytidine derivative on the stability of intramolecular i-motifs was investigated.
  145. RNA/aTNA Chimeras: RNAi Effects and Nucleases Resistance of Single and Double Stranded RNAs
  146. Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles
  147. Cationic vesicles based on non-ionic surfactant and synthetic aminolipids mediate delivery of antisense oligonucleotides into mammalian cells
  148. DNA Nanoarchitectures: Steps towards Biological Applications
  149. Quadruplex Nanostructures of d(TGGGGT): Influence of Sodium and Potassium Ions
  150. Oligonucleotide delivery: a patent review (2010 – 2013)
  151. Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water
  152. Direct Covalent Attachment of DNA Microarrays by Rapid Thiol–Ene “Click” Chemistry
  153. A Novel Formulation Based on 2,3-Di(tetradecyloxy)propan-1-amine Cationic Lipid Combined with Polysorbate 80 for Efficient Gene Delivery to the Retina
  154. to fold or to dimerize a dilema for modified TBA
  155. Fundamental aspects of the nucleic acid i-motif structures
  156. A novel cationic niosome formulation for gene delivery to the retina
  157. Challenges and Opportunities for Oligonucleotide-Based Therapeutics by Antisense and RNA Interference Mechanisms
  158. Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops
  159. Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells
  160. Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates
  161. DNA Origami as a DNA Repair Nanosensor at the Single-Molecule Level
  162. Electrostatic Binding and Hydrophobic Collapse of Peptide–Nucleic Acid Aggregates Quantified Using Force Spectroscopy
  163. Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
  164. Efficient Self-Assembly in Water of Long Noncovalent Polymers by Nucleobase Analogues
  165. Functionalization of the 3′-Ends of DNA and RNA Strands with N-ethyl-N-coupled Nucleosides: A Promising Approach To Avoid 3′-Exonuclease-Catalyzed Hydrolysis of Therapeutic Oligonucleotides
  166. Carbohydrate-DNA Interactions at G-Quadruplexes: Folding and Stability Changes by Attaching Sugars at the 5′-End
  167. The detection of a protein involved in coagulation using fluorescence
  168. Self-assembled G-quadruplex nanostructures: AFM and voltammetric characterization
  169. Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions
  170. 20 Supramolecular polymerization of nucleobase-like monomers in water
  171. Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene
  172. Oligonucleotide-Peptide Conjugates: Solid-Phase Synthesis under Acidic Conditions and Use in ELISA Assays
  173. Synthesis of Steroid–Oligonucleotide Conjugates for a DNA Site-Encoded SPR Immunosensor
  174. Receptor-Based Virtual Screening and Biological Characterization of Human Apurinic/Apyrimidinic Endonuclease (Ape1) Inhibitors
  175. Synthesis of Oligonucleotides Carrying Thiol Groups Using a Simple Reagent Derived from Threoninol
  176. Development of an impedimetric DNA-biosensor based on layered double hydroxide for the detection of long ssDNA sequences
  177. The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer
  178. Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives
  179. Impact of Methylation on the Physical Properties of DNA
  180. Structure of Triplex DNA in the Gas Phase
  181. Synthesis and Structural Characterization of Stable Branched DNA G-Quadruplexes Using the Trebler Phosphoramidite
  182. Synthesis and in vitro inhibition properties of oligonucleotide conjugates carrying amphipathic proline-rich peptide derivatives of the sweet arrow peptide (SAP)
  183. Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications
  184. Synthesis and in vitro Inhibition Properties of siRNA Conjugates Carrying Acridine and Quindoline Moieties
  185. Functionally Enhanced siRNA Targeting TNFα Attenuates DSS-induced Colitis and TLR-mediated Immunostimulation in Mice
  186. Facile Modification of Silica Substrates Provides a Platform for Direct‐Writing Surface Click Chemistry
  187. Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method
  188. Apolar carbohydrates as DNA capping agents
  189. Interstrand interactions on DNA duplexes modified by TTF units at the 3′ or 5′-ends
  190. Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5′-(C3TA2)4-3′ sequence of the human telomere
  191. Use of Oligonucleotides Carrying Photolabile Groups for the Control of the Deposition of Nanoparticles in Surfaces and Nanoparticle Association
  192. Functionalization of Surfaces with Synthetic Oligonucleotides
  193. Functionalization and Self-Assembly of DNA Bidimensional Arrays
  194. Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures
  195. A Direct, Efficient Method for the Preparation of siRNAs Containing Ribo-likeNorthBicyclo[3.1.0]hexane Pseudosugars
  196. Synthesis and Properties of Oligodeoxynucleotides Carrying 2-Aminopurine
  197. Evaluation of the structure–activity relationship of thrombin with thrombin binding aptamers by voltammetry and atomic force microscopy
  198. Effect of North Bicyclo[3.1.0]hexane 2′-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification
  199. Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/π Interactions
  200. Synthesis of Lipid-Oligonucleotide Conjugates for RNA Interference Studies
  201. Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
  202. Branched RNA: A New Architecture for RNA Interference
  203. Synthesis of Oligonucleotide–Peptide Conjugates for Biomedical and Technological Applications
  204. Synthesis and properties of small interfering RNA duplexes carrying 5-ethyluridine residues
  205. Synthesis and structural properties of oligonucleotides covalently linked to acridine and quindoline derivatives through a threoninol linker
  206. Chemical equilibria studies using multivariate analysis methods
  207. Synthesis of Oligonucleotides Carrying Amino Lipid Groups at the 3′-End for RNA Interference Studies
  208. Synthesis and Properties of Oligonucleotides Carrying Isoquinoline Imidazo[1,2-a]azine Fluorescent Units
  209. Solid-Phase Synthesis of Oligodeoxynucleotides Containing N4-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine Moieties
  210. Synthesis, Cell-Surface Binding, and Cellular Uptake of Fluorescently Labeled Glucose−DNA Conjugates with Different Carbohydrate Presentation
  211. Stepwise synthesis of oligonucleotide–peptide conjugates containing guanidinium and lipophilic groups in their 3′-termini
  212. Spectrometric study of the oligodeoxyribonucleotide protonation in aqueous solution
  213. Fabrication of patterned surfaces by photolithographic exposure of DNA hairpins carrying a novel photolabile group
  214. Triplex-Stabilizing Properties of Parallel Clamps Carrying LNA Derivatives at theHoogsteenStrand
  215. Modified siRNAs for the study of the PAZ domain
  216. Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection ofO6-Alkylguanine-DNA Alkyltransferase Activity
  217. G-Quadruplex Nucleic Acids
  218. Structural Properties of G,T-Parallel Duplexes
  219. Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers
  220. Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization
  221. pH-Modulated Watson–Crick Duplex–Quadruplex Equilibria of Guanine-Rich and Cytosine-Rich DNA Sequences 140 Base Pairs Upstream of thec-kitTranscription Initiation Site
  222. Modified Oligonucleotides for Biosensing Applications
  223. Unique Tautomeric and Recognition Properties of Thioketothymines?
  224. DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site
  225. α,γ-Peptide Nanotube Templating of One-Dimensional Parallel Fullerene Arrangements
  226. Assembly of Two-Dimensional DNA Crystals CarryingN4-[2-(tert-Butyldisulfanyl)ethyl]cytosine Residues
  227. Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer
  228. Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand
  229. Fluorescence site-encoded DNA addressable hapten microarray for anabolic androgenic steroids
  230. Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra
  231. Photocleavage of Peptides and Oligodeoxynucleotides Carrying 2-Nitrobenzyl Groups
  232. Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies
  233. Synthesis and Hybridization Properties of Modified Oligodeoxynucleotides Carrying Non-Natural Bases
  234. Amino-acids condensations in the preparation of Nα-9-fluorenylrnethyloxycarbonylamino-acids with 9-fluorenylmethylchloroformate
  235. Experimental Measurement of Carbohydrate-Aromatic Stacking in Water by Using a Dangling-Ended DNA Model System
  236. Study of the interaction between the G-quadruplex-forming thrombin-binding aptamer and the porphyrin 5,10,15,20-tetrakis-(N-methyl-4-pyridyl)-21,23H-porphyrin tetratosylate
  237. Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbones
  238. Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones
  239. Incorporation of Zebularine from its 2′-Deoxyribonucleoside Triphosphate Derivative and Activity as a Template-Coding Nucleobase
  240. 8-Amino guanine accelerates tetramolecular G-quadruplex formation
  241. Synthesis of Oligonucleotide Derivatives Using ChemMatrix Supports
  242. Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter
  243. Synthesis of Oligonucleotides Carrying 5′-5′ Linkages Using Copper-Catalyzed Cycloaddition Reactions
  244. A Flexible Method for the Fabrication of Gold Nanostructures Using Oligonucleotide Derivatives
  245. New developments in the synthesis of oligonucleotide-peptide conjugates
  246. Triplex Formation Using Oligonucleotide Clamps Carrying 8-Aminopurines
  247. ds-Oligonucleotide–Peptide Conjugates Featuring Peptides from the Leucine-Zipper Region of Fos as Switchable Receptors for the Oncoprotein Jun
  248. Analysis of Interaction between Dendriplexes and Bovine Serum Albumin
  249. Water-Soluble Carbosilane Dendrimers: Synthesis Biocompatibility and Complexation with Oligonucleotides; Evaluation for Medical Applications
  250. Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins
  251. First Characterization of a Biosensor for Large DNA Molecules using Quartz Crystal Microbalance and Impedance Spectroscopy
  252. Solid-Phase Synthesis of Modified Oligonucleotides
  253. Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the central base sequences -XGCY- and -XGGCCY- using multivariate methods
  254. Erratum
  255. Trimethylguanosine Nucleoside Inhibits Cross-Linking Between Snurportin 1 and m3G-CAPPED U1 snRNA
  256. Efficient Sequence-Specific Purification of Listeria innocua mRNA Species by Triplex Affinity Capture with Parallel Tail-Clamps
  257. Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand
  258. DNA-templated assembly of nanoscale architectures for next-generation electronic devices
  259. Strand Displacement of Double-Stranded DNA by Triplex-Forming Antiparallel Purine-Hairpins
  260. Destabilization of Quadruplex DNA by 8-Aminoguanine
  261. Magnetically Trigged Direct Electrochemical Detection of DNA Hybridization Using Au67Quantum Dot as Electrical Tracer
  262. Toward an ICPMS-Linked DNA Assay Based on Gold Nanoparticles Immunoconnected through Peptide Sequences
  263. A Straightforward Synthesis of 5‘-Peptide Oligonucleotide Conjugates UsingNα-Fmoc-Protected Amino Acids
  264. DNA-templated assembly of nanoscale architectures
  265. “Parallel” and “Antiparallel Tail-Clamps” Increase the Efficiency of Triplex Formation with Structured DNA and RNA Targets
  266. Synthesis and Triplex-Forming Properties of Cyclic Oligonucleotides with (G,A)-Antiparallel Strands
  267. Hybridization and Melting Behavior of Peptide Nucleic Acid (PNA) Oligonucleotide Chimeras Conjugated to Gold Nanoparticles
  268. DNA-Templated Assembly of a Protein-Functionalized Nanogap Electrode
  269. Synthesis of OligonucleotidePeptide Conjugates Carrying the c-myc Peptide Epitope as Recognition System
  270. Synthesis and Triple-Helix-Stabilization Properties of Branched Oligonucleotides Carrying 8-Aminoadenine Moieties
  271. Synthesis and Properties of Oligonucleotides Carrying Cryptolepine Derivatives
  272. Synthesis of Oligoribonucleotides Containing 4‐Thiouridine Using the Convertible Nucleoside Approach and the 1‐(2‐Fluorophenyl)‐4‐Methoxypiperidin‐4‐yl Group
  273. Transgenic Rice Plants Expressing the Antifungal AFP Protein from Aspergillus Giganteus Show Enhanced Resistance to the Rice Blast Fungus Magnaporthe Grisea
  274. Antiparallel Triple Helices. Structural Characteristics and Stabilization by 8-Amino Derivatives
  275. Potent Inhibition ofHhaI DNA Methylase by the Aglycon of 2-(1H)-Pyrimidinone Riboside (Zebularine) at the GCGC Recognition Domain
  276. Properties of Triple Helices Formed by Oligonucleotides Containing 8-Aminopurines
  277. Synthesis of Branched Oligonucleotides as Templates for the Assembly of Nanomaterials
  278. Convenient Synthesis of 8-Amino-2′-deoxyadenosine
  279. Peptide–PNA Conjugates: Targeted Transport of Antisense Therapeutics into Tumors
  280. Imaging the DNA and nanoparticle components of a self-assembled nanoscale architecture
  281. Synthesis of labelled PNA oligomers by a post-synthetic modification approach
  282. Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2?-deoxyzebularine
  283. DNA-Controlled Assembly of Protein-Modified Gold Nanocrystals
  284. Synthesis and properties of radiolabeled CPTA-oligonucleotides
  285. Nanotechnology: Carbon nanotubes with DNA recognition
  286. DNA triple helices and biomedicine
  287. Biofunctionalization of Silica-Coated CdTe and Gold Nanocrystals
  288. Inhibition of HhaI DNA (Cytosine-C5) Methyltransferase by Oligodeoxyribonucleotides Containing 5-Aza-2′-deoxycytidine: Examination of the Intertwined Roles of Co-factor, Target, Transition State Structure and Enzyme Conformation
  289. Additional Binding Sites for Anionic Phospholipids and Calcium Ions in the Crystal Structures of Complexes of the C2 Domain of Protein Kinase Cα
  290. Iodouracil-mediated photocrosslinking of DNA to EcoRII restriction endonuclease in catalytic conditions
  291. Hoogsteen-Based Parallel-Stranded Duplexes of DNA. Effect of 8-Amino-purine Derivatives
  292. Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides
  293. Parallel-stranded hairpins containing 8-aminopurines. novel efficient probes for triple-helix formation
  294. SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING 8-BROMO-2′-DEOXYGUANOSINE
  295. AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES
  296. Preparation and Evaluation of Tumor-Targeting Peptide−Oligonucleotide Conjugates
  297. Synthesis and Hybridization Properties of DNA–PNA Chimeras Carrying 5-Bromouracil and 5-Methylcytosine
  298. Intracellular distribution of digoxigenin-labeled phosphorothioate oligonucleotides
  299. Synthesis and Binding Properties of Oligonucleotides Carrying Nuclear Localization Sequences
  300. “Action-at-a-Distance” Mutagenesis
  301. Theoretical calculations, synthesis and base pairing properties of oligonucleotides containing 8-amino-2'-deoxyadenosine
  302. The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator
  303. Synthesis of Oligodeoxynucleotides ContainingN4-Mercaptoethylcytosine and Their Use in the Preparation of Oligonucleotide−Peptide Conjugates Carrying c-mycTag-Sequence
  304. Triple helix stabilization properties of oligonucleotides containing 8-amino-2′-deoxyguanosine
  305. Biochemical basis of SOS-induced mutagenesis in Escherichia coli : Reconstitution of in vitro lesion bypass dependent on the UmuD′ 2 C mutagenic complex an...
  306. Exonuclease−Polymerase Active Site Partitioning of Primer−Template DNA Strands and Equilibrium Mg2+Binding Properties of Bacteriophage T4 DNA Polymerase†
  307. A Second-Step Splicing Activity Is Conserved from Yeast to Human
  308. 2′-O-Propargyl oligoribonucleotides: Synthesis and hybridisation
  309. Tandem 5′-GA:GA-3′ mismatches account for the high stability of the fold-back structures formed by the centromeric Drosophila dodeca-satellite 1 1Edited by I. Tinoco
  310. Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine
  311. Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras
  312. Initiation of replication of plasmid pMV158: mechanisms of DNA strand-transfer reactions mediated by the initiator RepB protein
  313. A simple method for the synthesis of 2′-O-alkylguanosine derivatives
  314. Abasic Translesion Synthesis by DNA Polymerase β Violates the “A-rule”
  315. New carbamate supports for the preparation of 3′-amino-modified oligonucleotides
  316. Synthesis of 1,2-diacyl-sn-glycerophosphadidylserine from egg phosphatidylcholine by phosphoramidite Methodology
  317. NMR Study of the Conformation of the 2-Aminopurine:Cytosine Mismatch in DNA†
  318. Spectroscopic and Calorimetric Characterizations of DNA Duplexes Containing 2-Aminopurine†
  319. Divalent Zinc Cations Induce the Formation of Two Distinct Homoduplexes of a d(GA)20 DNA Sequence
  320. Preparation and properties of oligodeoxynucleotides containing 4-O-butylthymine, 2-fluorohypoxanthine and 5-azacytosine1
  321. Preparation of oligonucleotide-dexamethasone conjugates
  322. Preparation of Oligonucleotides Containing Non-natural Base Analogues
  323. Dam methylase fromEscherichia coli: kinetic studies using modified DNA oligomers: hemimethylated substrates
  324. Digoxigenin-Labeled Phosphorothioate Oligonucleotides: A New Tool for the Study of Cellular Uptake
  325. Synthesis and properties of oligonucleotides containing the mutagenic base O4-benzylthymidine
  326. Use of NPE-Protecting Groups for the Preparation of Oligonucleotides Without Using Nucleophiles During the Final Deprotection
  327. Use of oligonucleotide-alkaline phosphatase conjugates as non-radioactive probes for rapid analysis of a proteinase inhibitor gene fromZea mays
  328. Nucleotide Insertion and Primer Extension at Abasic Template Sites in Different Sequence Contexts
  329. Pre-Steady-State Kinetic Analysis of Sequence-Dependent Nucleotide Excision by the 3'-Exonuclease Activity of Bacteriophage T4 DNA Polymerase
  330. Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258
  331. Chemical synthesis of a fully active transcriptional repressor protein.
  332. Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids
  333. Synthesis of Oligodeoxyribonucleotides Containing 2,6-Diaminopurine
  334. Criteria for the economic large scale solid-phase synthesis of oligonucleotides
  335. Solid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids
  336. A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides
  337. Gel-phase 31P-NMR. A new analytical tool to evaluate solid phase oligonucleoside synthesis.
  338. Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence
  339. Detection of hepatitis B virus DNA in human serumsamples: Use of digoxigenin-labeled oligonucleotides as modified primers for the polymerase chain reaction
  340. -2-(2,4-dinitrophenyl)ethyloxycarbonyl-amino acids, new base labile protected derivatives suitable for solid-phase peptide synthesis.
  341. S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis
  342. A synthetic procedure for the preparation of oligonucleotides without using ammonia and its application for the synthesis of oligonucleotides containing 0-4-alkyl thymidines.
  343. Preparation of oligonucleotides containing dAICA using an unexpected side-reaction observed on a protected derivative of 2-aza-2′-deoxyinosine.
  344. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides II. Synthesis of protected peptides
  345. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides I : Synthesis of the supports and their application to oligonucleotide synthesis.
  346. Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence.
  347. Syhthesis of Oligonucleotides Containing 4-0-Ethylthymidine
  348. O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides
  349. Synthesis and characterization of oligodeoxynucleotides containing the mutagenic base analogue 4-O-ethylthymine
  350. Characterization of the high pH wobble structure of the 2-aminopurine·cytosine mismatch by N-15 NMR spectroscopy
  351. Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions
  352. Structural and Dynamic Properties of a Bromouracil-Adenine Base Pair in DNA Studied by Proton NMR
  353. NMR studies of the stable mismatch purine-thymine in the self-complementary d(CGPuAATTTCG) duplex in solution
  354. NMR studies on an oligodeoxynucleotide containing 2-aminopurine opposite adenine
  355. Synthesis of Oligonucleotides Containing the Abasic Site Model Compound 1,4-Anhydro-2-Deoxy-D-Ribitol
  356. An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations
  357. On the use of s-t-butylsulphenyl group for protection of cysteine in solid-phase peptide synthesis using fmoc-amino acids
  358. Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR.
  359. Convergent solid phase peptide synthesis-III
  360. Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine
  361. Synthesis and properties of oligonucleotides containing 2′-deoxynebularine and 2′-deoxyxanthosine
  362. Diketopiperazine formation in acetamido-and nitrobenzamido-bridgedpolymeric supports.