All Stories

  1. Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration
  2. Single‐Step Functionalization Strategy of Graphene Microtransistor Array with Chemically Modified Aptamers for Biosensing Applications
  3. Synthesis and Evaluation of 3′-Oleyl–Oligonucleotide Conjugates as Potential Cellular Uptake Enhancers
  4. Synthesis of 2′-O-Methyl/2′-O-MOE-L-Nucleoside Derivatives and Their Applications: Preparation of G-Quadruplexes, Their Characterization, and Stability Studies
  5. Special Issue “Frontiers in Nucleic Acid Chemistry—In Memory of Professor Enrique Pedroso for His Outstanding Contributions to Nucleic Acid Chemistry”
  6. Rapid and Highly Efficient Separation of i-Motif DNA Species by CE-UV and Multivariate Curve Resolution
  7. Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs)
  8. Detection of pyrimidine-rich DNA sequences based on the formation of parallel and antiparallel triplex DNA and fluorescent silver nanoclusters
  9. Exploring the stabilizing effect on the i-motif of neighboring structural motifs and drugs
  10. Stability of polymeric cationic niosomes and their plasmid DNA-based complexes as gene delivery carriers
  11. Evaluation of Poly(N-Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells
  12. Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs
  13. Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies
  14. Correction: Clua et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules 2022, 27, 3944
  15. Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)
  16. Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region
  17. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes
  18. Cover Picture: Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications (Chem. Rec. 4/2022)
  19. A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model
  20. Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications
  21. Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency
  22. Investigation of the Complexes Formed between PARP1 Inhibitors and PARP1 G-Quadruplex at the Gene Promoter Region
  23. Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines
  24. Biodistribution of 68/67Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging
  25. Exploring the Interaction of Curaxin CBL0137 with G-Quadruplex DNA Oligomers
  26. The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis
  27. Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake
  28. Structural Effects of Incorporation of 2'‐Deoxy‐2'2'‐Difluorodeoxycytidine (Gemcitabine) in A‐ and B‐Form Duplexes
  29. Parallel G-quadruplex Structures Increase Cellular Uptake and Cytotoxicity of 5-Fluoro-2′-deoxyuridine Oligomers in 5-Fluorouracil Resistant Cells
  30. Biomedical Applications of DNA-nanostructures
  31. EcoRII Restriction Endonuclease Forms Specific Contacts to the Bases of Its Target Sequence Flipped from DNA in a Transition Complex with Photoactivatable Substrates
  32. G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide
  33. Oligonucleotides Containing 1-Aminomethyl or 1-Mercaptomethyl-2-deoxy-d-ribofuranoses: Synthesis, Purification, Characterization, and Conjugation with Fluorophores and Lipids
  34. Nanoparticles for Brain Drug Delivery
  35. Nucleic Acids Chemistry
  36. Preparation of Lipid-Conjugated siRNA Oligonucleotides for Enhanced Gene Inhibition in Mammalian Cells
  37. Studies on the interactions of Ag(i) with DNA and their implication on the DNA-templated synthesis of silver nanoclusters and on the interaction with complementary DNA and RNA sequences
  38. Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles
  39. Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery
  40. Developing Protein–Antitumoral Drug Nanoconjugates as Bifunctional Antimicrobial Agents
  41. Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples
  42. Study of alkaloid berberine and its interaction with the human telomeric i-motif DNA structure
  43. Sorting hidden patterns in nanoparticle performance for glioblastoma using machine learning algorithms
  44. Non-viral mediated gene therapy in human cystic fibrosis airway epithelial cells recovers chloride channel functionality
  45. Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter region of the SMARCA4 gene
  46. Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins
  47. Fast and Accurate Pneumocystis Pneumonia Diagnosis in Human Samples Using a Label-Free Plasmonic Biosensor
  48. Brain Angiogenesis Induced by Nonviral Gene Therapy with Potential Therapeutic Benefits for Central Nervous System Diseases
  49. Niosome-Based Approach for In Situ Gene Delivery to Retina and Brain Cortex as Immune-Privileged Tissues
  50. Ethylcellulose nanoparticles as a new “in vitro” transfection tool for antisense oligonucleotide delivery
  51. Sulfonamide as amide isostere for fine-tuning the gelation properties of physical gels
  52. Liposomes‐ in ‐Chitosan Hydrogels: Challenges and Opportunities for Biomedical Applications
  53. Alginate Hydrogels as Scaffolds and Delivery Systems to Repair the Damaged Spinal Cord
  54. A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor
  55. Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41
  56. Aptamer-peptide conjugates as a new strategy to modulate human α-thrombin binding affinity
  57. Cationic niosome-based hBMP7 gene transfection of neuronal precursor NT2 cells to reduce the migration of glioma cells in vitro
  58. Study of conformational transitions of i-motif DNA using time-resolved fluorescence and multivariate analysis methods
  59. Gene delivery to the rat retina by non-viral vectors based on chloroquine-containing cationic niosomes
  60. The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry
  61. Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
  62. On the Race for More Stretchable and Tough Hydrogels
  63. Parallel Clamps and Polypurine Hairpins (PPRH) for Gene Silencing and Triplex‐Affinity Capture: Design, Synthesis, and Use
  64. Efficient bioactive oligonucleotide‐protein conjugation for cell‐targeted cancer therapy
  65. Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
  66. Expanding the limits of amide–triazole isosteric substitution in bisamide-based physical gels
  67. Overview of DNA Self-Assembling: Progresses in Biomedical Applications
  68. Detection of a microRNA involved in human disease
  69. Detection of DNA methylation
  70. Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles
  71. Synthesis of Oligonucleotides Carrying Nucleic Acid Derivatives of Biomedical and Structural Interest
  72. Successful evaluation of a nanodrug against metastasis
  73. Preparation of new compounds with interesting porperties in biomedicine
  74. siRNA Modified with 2′-Deoxy-2′-C -methylpyrimidine Nucleosides
  75. Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques
  76. Synthesis, Characterization, and Self-Assembly of a Tetrathiafulvalene (TTF)–Triglycyl Derivative
  77. Isosteric Substitution of 4H-1,2,4-Triazole by 1H-1,2,3-Triazole in Isophthalic Derivative Enabled Hydrogel Formation for Controlled Drug Delivery
  78. Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates
  79. Stem cell-based gene delivery mediated by cationic niosomes for bone regeneration
  80. Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study
  81. DNA-based nanoscaffolds as vehicles for 5-fluoro-2′-deoxyuridine oligomers in colorectal cancer therapy
  82. Electrochemical and AFM Characterization of G-Quadruplex Electrochemical Biosensors and Applications
  83. Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
  84. Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes
  85. Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling
  86. AS1411-decorated niosomes as effective nanocarriers for Ru(iii)-based drugs in anticancer strategies
  87. Lipid-Oligonucleotide Conjugates Forming G-Quadruplexes (Lipoquads) as Potent Inhibitors of HIV Entry
  88. i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene
  89. DNA-Origami-Aided Lithography for Sub-10 Nanometer Pattern Printing
  90. Biochemistry of RNA Silencing
  91. Cover Picture: Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues (ChemBioChem 12/2017)
  92. Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties
  93. Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues
  94. The effect of l -thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures
  95. Erratum: Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
  96. Antiviral activity of lipid-DNA molecules
  97. DNA-Origami-Driven Lithography for Patterning on Gold Surfaces with Sub-10 nm Resolution
  98. Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels
  99. Cationic nioplexes-in-polysaccharide-based hydrogels as versatile biodegradable hybrid materials to deliver nucleic acids
  100. Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms
  101. The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biological properties of oligonucleotides
  102. Meet Our Editorial Board Member
  103. Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA
  104. Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
  105. The role of helper lipids in the intracellular disposition and transfection efficiency of niosome formulations for gene delivery to retinal pigment epithelial cells
  106. The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA
  107. siRNA and RNAi optimization
  108. The influence of the polar head-group of synthetic cationic lipids on the transfection efficiency mediated by niosomes in rat retina and brain
  109. Biodegradable liposome-encapsulated hydrogels for biomedical applications: a marriage of convenience
  110. Cellular uptake studies of antisense oligonucleotides using G-quadruplex-nanostructures. The effect of cationic residue on the biophysical and biological properties
  111. Nioplexes encapsulated in supramolecular hybrid biohydrogels as versatile delivery platforms for nucleic acids
  112. Understanding the effect of the nature of the nucleobase in the loops on the stability of the i-motif structure
  113. Label-free electrochemical DNA sensor using “click”-functionalized PEDOT electrodes
  114. Sensitive and label-free detection of miRNA-145 by triplex formation
  115. Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers
  116. 1-[2,3-Bis(tetradecyloxy)propyl]-3-[2-(piperazin-1-yl)ethyl]urea
  117. New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
  118. Synthesis of oligonucleotides carrying fluorescently labelled O6-alkylguanine for measuring hAGT activity
  119. RNA modified with acyclic threoninol nucleic acids for RNA interference
  120. Protamine/DNA/Niosome Ternary Nonviral Vectors for Gene Delivery to the Retina: The Role of Protamine
  121. Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences
  122. Modulation of the RNA Interference Activity Using Central Mismatched siRNAs and Acyclic Threoninol Nucleic Acids (aTNA) Units
  123. Glucose Conjugation of Anti-HIV-1 Oligonucleotides Containing Unmethylated CpG Motifs Reduces Their Immunostimulatory Activity
  124. Niosomes based on synthetic cationic lipids for gene delivery: the influence of polar head-groups on the transfection efficiency in HEK-293, ARPE-19 and MSC-D1 cells
  125. Novel non-viral gene delivery systems composed of carbosilane dendron functionalized nanoparticles prepared from nano-emulsions as non-viral carriers for antisense oligonucleotides
  126. The effect of a cytidine derivative on the stability of intramolecular i-motifs was investigated.
  127. RNA/aTNA Chimeras: RNAi Effects and Nucleases Resistance of Single and Double Stranded RNAs
  128. Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles
  129. Cationic vesicles based on non-ionic surfactant and synthetic aminolipids mediate delivery of antisense oligonucleotides into mammalian cells
  130. DNA Nanoarchitectures: Steps towards Biological Applications
  131. Quadruplex Nanostructures of d(TGGGGT): Influence of Sodium and Potassium Ions
  132. Oligonucleotide delivery: a patent review (2010 – 2013)
  133. Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water
  134. Direct Covalent Attachment of DNA Microarrays by Rapid Thiol–Ene “Click” Chemistry
  135. A Novel Formulation Based on 2,3-Di(tetradecyloxy)propan-1-amine Cationic Lipid Combined with Polysorbate 80 for Efficient Gene Delivery to the Retina
  136. to fold or to dimerize a dilema for modified TBA
  137. Fundamental aspects of the nucleic acid i-motif structures
  138. A novel cationic niosome formulation for gene delivery to the retina
  139. Challenges and Opportunities for Oligonucleotide-Based Therapeutics by Antisense and RNA Interference Mechanisms
  140. Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops
  141. Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells
  142. Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates
  143. DNA Origami as a DNA Repair Nanosensor at the Single-Molecule Level
  144. Electrostatic Binding and Hydrophobic Collapse of Peptide–Nucleic Acid Aggregates Quantified Using Force Spectroscopy
  145. Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
  146. Efficient Self-Assembly in Water of Long Noncovalent Polymers by Nucleobase Analogues
  147. Functionalization of the 3′-Ends of DNA and RNA Strands with N-ethyl-N-coupled Nucleosides: A Promising Approach To Avoid 3′-Exonuclease-Catalyzed Hydrolysis of Therapeutic Oligonucleotides
  148. Carbohydrate-DNA Interactions at G-Quadruplexes: Folding and Stability Changes by Attaching Sugars at the 5′-End
  149. The detection of a protein involved in coagulation using fluorescence
  150. Self-assembled G-quadruplex nanostructures: AFM and voltammetric characterization
  151. Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions
  152. 20 Supramolecular polymerization of nucleobase-like monomers in water
  153. Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene
  154. Oligonucleotide-Peptide Conjugates: Solid-Phase Synthesis under Acidic Conditions and Use in ELISA Assays
  155. Synthesis of Steroid–Oligonucleotide Conjugates for a DNA Site-Encoded SPR Immunosensor
  156. Receptor-Based Virtual Screening and Biological Characterization of Human Apurinic/Apyrimidinic Endonuclease (Ape1) Inhibitors
  157. Synthesis of Oligonucleotides Carrying Thiol Groups Using a Simple Reagent Derived from Threoninol
  158. Development of an impedimetric DNA-biosensor based on layered double hydroxide for the detection of long ssDNA sequences
  159. The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer
  160. Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives
  161. Impact of Methylation on the Physical Properties of DNA
  162. Structure of Triplex DNA in the Gas Phase
  163. Synthesis and Structural Characterization of Stable Branched DNA G-Quadruplexes Using the Trebler Phosphoramidite
  164. Synthesis and in vitro inhibition properties of oligonucleotide conjugates carrying amphipathic proline-rich peptide derivatives of the sweet arrow peptide (SAP)
  165. Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications
  166. Synthesis and in vitro Inhibition Properties of siRNA Conjugates Carrying Acridine and Quindoline Moieties
  167. Functionally Enhanced siRNA Targeting TNFα Attenuates DSS-induced Colitis and TLR-mediated Immunostimulation in Mice
  168. Facile Modification of Silica Substrates Provides a Platform for Direct‐Writing Surface Click Chemistry
  169. Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method
  170. Apolar carbohydrates as DNA capping agents
  171. Interstrand interactions on DNA duplexes modified by TTF units at the 3′ or 5′-ends
  172. Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5′-(C3TA2)4-3′ sequence of the human telomere
  173. Use of Oligonucleotides Carrying Photolabile Groups for the Control of the Deposition of Nanoparticles in Surfaces and Nanoparticle Association
  174. Functionalization of Surfaces with Synthetic Oligonucleotides
  175. Functionalization and Self-Assembly of DNA Bidimensional Arrays
  176. Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures
  177. A Direct, Efficient Method for the Preparation of siRNAs Containing Ribo-likeNorthBicyclo[3.1.0]hexane Pseudosugars
  178. Synthesis and Properties of Oligodeoxynucleotides Carrying 2-Aminopurine
  179. Evaluation of the structure–activity relationship of thrombin with thrombin binding aptamers by voltammetry and atomic force microscopy
  180. Effect of North Bicyclo[3.1.0]hexane 2′-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification
  181. Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/π Interactions
  182. Synthesis of Lipid-Oligonucleotide Conjugates for RNA Interference Studies
  183. Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
  184. Branched RNA: A New Architecture for RNA Interference
  185. Synthesis of Oligonucleotide–Peptide Conjugates for Biomedical and Technological Applications
  186. Synthesis and properties of small interfering RNA duplexes carrying 5-ethyluridine residues
  187. Synthesis and structural properties of oligonucleotides covalently linked to acridine and quindoline derivatives through a threoninol linker
  188. Chemical equilibria studies using multivariate analysis methods
  189. Synthesis of Oligonucleotides Carrying Amino Lipid Groups at the 3′-End for RNA Interference Studies
  190. Synthesis and Properties of Oligonucleotides Carrying Isoquinoline Imidazo[1,2-a]azine Fluorescent Units
  191. Solid-Phase Synthesis of Oligodeoxynucleotides Containing N4-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine Moieties
  192. Synthesis, Cell-Surface Binding, and Cellular Uptake of Fluorescently Labeled Glucose−DNA Conjugates with Different Carbohydrate Presentation
  193. Stepwise synthesis of oligonucleotide–peptide conjugates containing guanidinium and lipophilic groups in their 3′-termini
  194. Spectrometric study of the oligodeoxyribonucleotide protonation in aqueous solution
  195. Fabrication of patterned surfaces by photolithographic exposure of DNA hairpins carrying a novel photolabile group
  196. Triplex-Stabilizing Properties of Parallel Clamps Carrying LNA Derivatives at theHoogsteenStrand
  197. Modified siRNAs for the study of the PAZ domain
  198. Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection ofO6-Alkylguanine-DNA Alkyltransferase Activity
  199. G-Quadruplex Nucleic Acids
  200. Structural Properties of G,T-Parallel Duplexes
  201. Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers
  202. Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization
  203. pH-Modulated Watson–Crick Duplex–Quadruplex Equilibria of Guanine-Rich and Cytosine-Rich DNA Sequences 140 Base Pairs Upstream of thec-kitTranscription Initiation Site
  204. Modified Oligonucleotides for Biosensing Applications
  205. Unique Tautomeric and Recognition Properties of Thioketothymines?
  206. DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site
  207. α,γ-Peptide Nanotube Templating of One-Dimensional Parallel Fullerene Arrangements
  208. Assembly of Two-Dimensional DNA Crystals CarryingN4-[2-(tert-Butyldisulfanyl)ethyl]cytosine Residues
  209. Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer
  210. Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand
  211. Fluorescence site-encoded DNA addressable hapten microarray for anabolic androgenic steroids
  212. Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra
  213. Photocleavage of Peptides and Oligodeoxynucleotides Carrying 2-Nitrobenzyl Groups
  214. Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies
  215. Synthesis and Hybridization Properties of Modified Oligodeoxynucleotides Carrying Non-Natural Bases
  216. Amino-acids condensations in the preparation of Nα-9-fluorenylrnethyloxycarbonylamino-acids with 9-fluorenylmethylchloroformate
  217. Experimental Measurement of Carbohydrate-Aromatic Stacking in Water by Using a Dangling-Ended DNA Model System
  218. Study of the interaction between the G-quadruplex-forming thrombin-binding aptamer and the porphyrin 5,10,15,20-tetrakis-(N-methyl-4-pyridyl)-21,23H-porphyrin tetratosylate
  219. Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbones
  220. Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones
  221. Incorporation of Zebularine from its 2′-Deoxyribonucleoside Triphosphate Derivative and Activity as a Template-Coding Nucleobase
  222. 8-Amino guanine accelerates tetramolecular G-quadruplex formation
  223. Synthesis of Oligonucleotide Derivatives Using ChemMatrix Supports
  224. Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter
  225. Synthesis of Oligonucleotides Carrying 5′-5′ Linkages Using Copper-Catalyzed Cycloaddition Reactions
  226. A Flexible Method for the Fabrication of Gold Nanostructures Using Oligonucleotide Derivatives
  227. New developments in the synthesis of oligonucleotide-peptide conjugates
  228. Triplex Formation Using Oligonucleotide Clamps Carrying 8-Aminopurines
  229. ds-Oligonucleotide–Peptide Conjugates Featuring Peptides from the Leucine-Zipper Region of Fos as Switchable Receptors for the Oncoprotein Jun
  230. Analysis of Interaction between Dendriplexes and Bovine Serum Albumin
  231. Water-Soluble Carbosilane Dendrimers: Synthesis Biocompatibility and Complexation with Oligonucleotides; Evaluation for Medical Applications
  232. Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins
  233. First Characterization of a Biosensor for Large DNA Molecules using Quartz Crystal Microbalance and Impedance Spectroscopy
  234. Solid-Phase Synthesis of Modified Oligonucleotides
  235. Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the central base sequences -XGCY- and -XGGCCY- using multivariate methods
  236. Erratum
  237. Trimethylguanosine Nucleoside Inhibits Cross-Linking Between Snurportin 1 and m3G-CAPPED U1 snRNA
  238. Efficient Sequence-Specific Purification of Listeria innocua mRNA Species by Triplex Affinity Capture with Parallel Tail-Clamps
  239. Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand
  240. DNA-templated assembly of nanoscale architectures for next-generation electronic devices
  241. Strand Displacement of Double-Stranded DNA by Triplex-Forming Antiparallel Purine-Hairpins
  242. Destabilization of Quadruplex DNA by 8-Aminoguanine
  243. Magnetically Trigged Direct Electrochemical Detection of DNA Hybridization Using Au67Quantum Dot as Electrical Tracer
  244. Toward an ICPMS-Linked DNA Assay Based on Gold Nanoparticles Immunoconnected through Peptide Sequences
  245. A Straightforward Synthesis of 5‘-Peptide Oligonucleotide Conjugates UsingNα-Fmoc-Protected Amino Acids
  246. DNA-templated assembly of nanoscale architectures
  247. “Parallel” and “Antiparallel Tail-Clamps” Increase the Efficiency of Triplex Formation with Structured DNA and RNA Targets
  248. Synthesis and Triplex-Forming Properties of Cyclic Oligonucleotides with (G,A)-Antiparallel Strands
  249. Hybridization and Melting Behavior of Peptide Nucleic Acid (PNA) Oligonucleotide Chimeras Conjugated to Gold Nanoparticles
  250. DNA-Templated Assembly of a Protein-Functionalized Nanogap Electrode
  251. Synthesis of OligonucleotidePeptide Conjugates Carrying the c-myc Peptide Epitope as Recognition System
  252. Synthesis and Triple-Helix-Stabilization Properties of Branched Oligonucleotides Carrying 8-Aminoadenine Moieties
  253. Synthesis and Properties of Oligonucleotides Carrying Cryptolepine Derivatives
  254. Synthesis of Oligoribonucleotides Containing 4‐Thiouridine Using the Convertible Nucleoside Approach and the 1‐(2‐Fluorophenyl)‐4‐Methoxypiperidin‐4‐yl Group
  255. Transgenic Rice Plants Expressing the Antifungal AFP Protein from Aspergillus Giganteus Show Enhanced Resistance to the Rice Blast Fungus Magnaporthe Grisea
  256. Antiparallel Triple Helices. Structural Characteristics and Stabilization by 8-Amino Derivatives
  257. Potent Inhibition ofHhaI DNA Methylase by the Aglycon of 2-(1H)-Pyrimidinone Riboside (Zebularine) at the GCGC Recognition Domain
  258. Properties of Triple Helices Formed by Oligonucleotides Containing 8-Aminopurines
  259. Synthesis of Branched Oligonucleotides as Templates for the Assembly of Nanomaterials
  260. Convenient Synthesis of 8-Amino-2′-deoxyadenosine
  261. Peptide–PNA Conjugates: Targeted Transport of Antisense Therapeutics into Tumors
  262. Imaging the DNA and nanoparticle components of a self-assembled nanoscale architecture
  263. Synthesis of labelled PNA oligomers by a post-synthetic modification approach
  264. Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2?-deoxyzebularine
  265. DNA-Controlled Assembly of Protein-Modified Gold Nanocrystals
  266. Synthesis and properties of radiolabeled CPTA-oligonucleotides
  267. Nanotechnology: Carbon nanotubes with DNA recognition
  268. DNA triple helices and biomedicine
  269. Biofunctionalization of Silica-Coated CdTe and Gold Nanocrystals
  270. Inhibition of HhaI DNA (Cytosine-C5) Methyltransferase by Oligodeoxyribonucleotides Containing 5-Aza-2′-deoxycytidine: Examination of the Intertwined Roles of Co-factor, Target, Transition State Structure and Enzyme Conformation
  271. Additional Binding Sites for Anionic Phospholipids and Calcium Ions in the Crystal Structures of Complexes of the C2 Domain of Protein Kinase Cα
  272. Iodouracil-mediated photocrosslinking of DNA to EcoRII restriction endonuclease in catalytic conditions
  273. Hoogsteen-Based Parallel-Stranded Duplexes of DNA. Effect of 8-Amino-purine Derivatives
  274. Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides
  275. Parallel-stranded hairpins containing 8-aminopurines. novel efficient probes for triple-helix formation
  276. SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING 8-BROMO-2′-DEOXYGUANOSINE
  277. AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES
  278. Preparation and Evaluation of Tumor-Targeting Peptide−Oligonucleotide Conjugates
  279. Synthesis and Hybridization Properties of DNA–PNA Chimeras Carrying 5-Bromouracil and 5-Methylcytosine
  280. Intracellular distribution of digoxigenin-labeled phosphorothioate oligonucleotides
  281. Synthesis and Binding Properties of Oligonucleotides Carrying Nuclear Localization Sequences
  282. “Action-at-a-Distance” Mutagenesis
  283. Theoretical calculations, synthesis and base pairing properties of oligonucleotides containing 8-amino-2'-deoxyadenosine
  284. The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator
  285. Synthesis of Oligodeoxynucleotides ContainingN4-Mercaptoethylcytosine and Their Use in the Preparation of Oligonucleotide−Peptide Conjugates Carrying c-mycTag-Sequence
  286. Triple helix stabilization properties of oligonucleotides containing 8-amino-2′-deoxyguanosine
  287. Biochemical basis of SOS-induced mutagenesis in Escherichia coli : Reconstitution of in vitro lesion bypass dependent on the UmuD′ 2 C mutagenic complex an...
  288. Exonuclease−Polymerase Active Site Partitioning of Primer−Template DNA Strands and Equilibrium Mg2+Binding Properties of Bacteriophage T4 DNA Polymerase†
  289. A Second-Step Splicing Activity Is Conserved from Yeast to Human
  290. 2′-O-Propargyl oligoribonucleotides: Synthesis and hybridisation
  291. Tandem 5′-GA:GA-3′ mismatches account for the high stability of the fold-back structures formed by the centromeric Drosophila dodeca-satellite 1 1Edited by I. Tinoco
  292. Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine
  293. Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras
  294. Initiation of replication of plasmid pMV158: mechanisms of DNA strand-transfer reactions mediated by the initiator RepB protein
  295. A simple method for the synthesis of 2′-O-alkylguanosine derivatives
  296. Abasic Translesion Synthesis by DNA Polymerase β Violates the “A-rule”
  297. New carbamate supports for the preparation of 3′-amino-modified oligonucleotides
  298. Synthesis of 1,2-diacyl-sn-glycerophosphadidylserine from egg phosphatidylcholine by phosphoramidite Methodology
  299. NMR Study of the Conformation of the 2-Aminopurine:Cytosine Mismatch in DNA†
  300. Spectroscopic and Calorimetric Characterizations of DNA Duplexes Containing 2-Aminopurine†
  301. Divalent Zinc Cations Induce the Formation of Two Distinct Homoduplexes of a d(GA)20 DNA Sequence
  302. Preparation and properties of oligodeoxynucleotides containing 4-O-butylthymine, 2-fluorohypoxanthine and 5-azacytosine1
  303. Preparation of oligonucleotide-dexamethasone conjugates
  304. Preparation of Oligonucleotides Containing Non-natural Base Analogues
  305. Dam methylase fromEscherichia coli: kinetic studies using modified DNA oligomers: hemimethylated substrates
  306. Digoxigenin-Labeled Phosphorothioate Oligonucleotides: A New Tool for the Study of Cellular Uptake
  307. Synthesis and properties of oligonucleotides containing the mutagenic base O4-benzylthymidine
  308. Use of NPE-Protecting Groups for the Preparation of Oligonucleotides Without Using Nucleophiles During the Final Deprotection
  309. Use of oligonucleotide-alkaline phosphatase conjugates as non-radioactive probes for rapid analysis of a proteinase inhibitor gene fromZea mays
  310. Nucleotide Insertion and Primer Extension at Abasic Template Sites in Different Sequence Contexts
  311. Pre-Steady-State Kinetic Analysis of Sequence-Dependent Nucleotide Excision by the 3'-Exonuclease Activity of Bacteriophage T4 DNA Polymerase
  312. Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258
  313. Chemical synthesis of a fully active transcriptional repressor protein.
  314. Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids
  315. Synthesis of Oligodeoxyribonucleotides Containing 2,6-Diaminopurine
  316. Criteria for the economic large scale solid-phase synthesis of oligonucleotides
  317. Solid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids
  318. A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides
  319. Gel-phase 31P-NMR. A new analytical tool to evaluate solid phase oligonucleoside synthesis.
  320. Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence
  321. Detection of hepatitis B virus DNA in human serumsamples: Use of digoxigenin-labeled oligonucleotides as modified primers for the polymerase chain reaction
  322. -2-(2,4-dinitrophenyl)ethyloxycarbonyl-amino acids, new base labile protected derivatives suitable for solid-phase peptide synthesis.
  323. S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis
  324. A synthetic procedure for the preparation of oligonucleotides without using ammonia and its application for the synthesis of oligonucleotides containing 0-4-alkyl thymidines.
  325. Preparation of oligonucleotides containing dAICA using an unexpected side-reaction observed on a protected derivative of 2-aza-2′-deoxyinosine.
  326. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides II. Synthesis of protected peptides
  327. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides I : Synthesis of the supports and their application to oligonucleotide synthesis.
  328. Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence.
  329. Syhthesis of Oligonucleotides Containing 4-0-Ethylthymidine
  330. O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides
  331. Synthesis and characterization of oligodeoxynucleotides containing the mutagenic base analogue 4-O-ethylthymine
  332. Characterization of the high pH wobble structure of the 2-aminopurine·cytosine mismatch by N-15 NMR spectroscopy
  333. Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions
  334. Structural and Dynamic Properties of a Bromouracil-Adenine Base Pair in DNA Studied by Proton NMR
  335. NMR studies of the stable mismatch purine-thymine in the self-complementary d(CGPuAATTTCG) duplex in solution
  336. NMR studies on an oligodeoxynucleotide containing 2-aminopurine opposite adenine
  337. Synthesis of Oligonucleotides Containing the Abasic Site Model Compound 1,4-Anhydro-2-Deoxy-D-Ribitol
  338. An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations
  339. On the use of s-t-butylsulphenyl group for protection of cysteine in solid-phase peptide synthesis using fmoc-amino acids
  340. Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR.
  341. Convergent solid phase peptide synthesis-III
  342. Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine
  343. Synthesis and properties of oligonucleotides containing 2′-deoxynebularine and 2′-deoxyxanthosine
  344. Diketopiperazine formation in acetamido-and nitrobenzamido-bridgedpolymeric supports.