All Stories

  1. Biophysical evaluation of antiparallel triplexes for biosensing and biomedical applications
  2. Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration
  3. Single‐Step Functionalization Strategy of Graphene Microtransistor Array with Chemically Modified Aptamers for Biosensing Applications
  4. Synthesis and Evaluation of 3′-Oleyl–Oligonucleotide Conjugates as Potential Cellular Uptake Enhancers
  5. Synthesis of 2′-O-Methyl/2′-O-MOE-L-Nucleoside Derivatives and Their Applications: Preparation of G-Quadruplexes, Their Characterization, and Stability Studies
  6. Special Issue “Frontiers in Nucleic Acid Chemistry—In Memory of Professor Enrique Pedroso for His Outstanding Contributions to Nucleic Acid Chemistry”
  7. Rapid and Highly Efficient Separation of i-Motif DNA Species by CE-UV and Multivariate Curve Resolution
  8. Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs)
  9. Detection of pyrimidine-rich DNA sequences based on the formation of parallel and antiparallel triplex DNA and fluorescent silver nanoclusters
  10. Exploring the stabilizing effect on the i-motif of neighboring structural motifs and drugs
  11. Stability of polymeric cationic niosomes and their plasmid DNA-based complexes as gene delivery carriers
  12. Evaluation of Poly(N-Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells
  13. Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs
  14. Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies
  15. Correction: Clua et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules 2022, 27, 3944
  16. Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)
  17. Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region
  18. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes
  19. Cover Picture: Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications (Chem. Rec. 4/2022)
  20. A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model
  21. Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications
  22. Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency
  23. Investigation of the Complexes Formed between PARP1 Inhibitors and PARP1 G-Quadruplex at the Gene Promoter Region
  24. Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines
  25. Biodistribution of 68/67Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging
  26. Exploring the Interaction of Curaxin CBL0137 with G-Quadruplex DNA Oligomers
  27. The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis
  28. Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake
  29. Structural Effects of Incorporation of 2'‐Deoxy‐2'2'‐Difluorodeoxycytidine (Gemcitabine) in A‐ and B‐Form Duplexes
  30. Parallel G-quadruplex Structures Increase Cellular Uptake and Cytotoxicity of 5-Fluoro-2′-deoxyuridine Oligomers in 5-Fluorouracil Resistant Cells
  31. Biomedical Applications of DNA-nanostructures
  32. EcoRII Restriction Endonuclease Forms Specific Contacts to the Bases of Its Target Sequence Flipped from DNA in a Transition Complex with Photoactivatable Substrates
  33. G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide
  34. Oligonucleotides Containing 1-Aminomethyl or 1-Mercaptomethyl-2-deoxy-d-ribofuranoses: Synthesis, Purification, Characterization, and Conjugation with Fluorophores and Lipids
  35. Nanoparticles for Brain Drug Delivery
  36. Nucleic Acids Chemistry
  37. Preparation of Lipid-Conjugated siRNA Oligonucleotides for Enhanced Gene Inhibition in Mammalian Cells
  38. Studies on the interactions of Ag(i) with DNA and their implication on the DNA-templated synthesis of silver nanoclusters and on the interaction with complementary DNA and RNA sequences
  39. Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles
  40. Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery
  41. Developing Protein–Antitumoral Drug Nanoconjugates as Bifunctional Antimicrobial Agents
  42. Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples
  43. Study of alkaloid berberine and its interaction with the human telomeric i-motif DNA structure
  44. Sorting hidden patterns in nanoparticle performance for glioblastoma using machine learning algorithms
  45. Non-viral mediated gene therapy in human cystic fibrosis airway epithelial cells recovers chloride channel functionality
  46. Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter region of the SMARCA4 gene
  47. Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins
  48. Fast and Accurate Pneumocystis Pneumonia Diagnosis in Human Samples Using a Label-Free Plasmonic Biosensor
  49. Brain Angiogenesis Induced by Nonviral Gene Therapy with Potential Therapeutic Benefits for Central Nervous System Diseases
  50. Niosome-Based Approach for In Situ Gene Delivery to Retina and Brain Cortex as Immune-Privileged Tissues
  51. Ethylcellulose nanoparticles as a new “in vitro” transfection tool for antisense oligonucleotide delivery
  52. Sulfonamide as amide isostere for fine-tuning the gelation properties of physical gels
  53. Liposomes‐ in ‐Chitosan Hydrogels: Challenges and Opportunities for Biomedical Applications
  54. Alginate Hydrogels as Scaffolds and Delivery Systems to Repair the Damaged Spinal Cord
  55. A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor
  56. Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41
  57. Aptamer-peptide conjugates as a new strategy to modulate human α-thrombin binding affinity
  58. Cationic niosome-based hBMP7 gene transfection of neuronal precursor NT2 cells to reduce the migration of glioma cells in vitro
  59. Study of conformational transitions of i-motif DNA using time-resolved fluorescence and multivariate analysis methods
  60. Gene delivery to the rat retina by non-viral vectors based on chloroquine-containing cationic niosomes
  61. The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry
  62. Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
  63. On the Race for More Stretchable and Tough Hydrogels
  64. Parallel Clamps and Polypurine Hairpins (PPRH) for Gene Silencing and Triplex‐Affinity Capture: Design, Synthesis, and Use
  65. Efficient bioactive oligonucleotide‐protein conjugation for cell‐targeted cancer therapy
  66. Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
  67. Expanding the limits of amide–triazole isosteric substitution in bisamide-based physical gels
  68. Overview of DNA Self-Assembling: Progresses in Biomedical Applications
  69. Detection of a microRNA involved in human disease
  70. Detection of DNA methylation
  71. Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles
  72. Synthesis of Oligonucleotides Carrying Nucleic Acid Derivatives of Biomedical and Structural Interest
  73. Successful evaluation of a nanodrug against metastasis
  74. Preparation of new compounds with interesting porperties in biomedicine
  75. siRNA Modified with 2′-Deoxy-2′-C -methylpyrimidine Nucleosides
  76. Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques
  77. Synthesis, Characterization, and Self-Assembly of a Tetrathiafulvalene (TTF)–Triglycyl Derivative
  78. Isosteric Substitution of 4H-1,2,4-Triazole by 1H-1,2,3-Triazole in Isophthalic Derivative Enabled Hydrogel Formation for Controlled Drug Delivery
  79. Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates
  80. Stem cell-based gene delivery mediated by cationic niosomes for bone regeneration
  81. Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study
  82. DNA-based nanoscaffolds as vehicles for 5-fluoro-2′-deoxyuridine oligomers in colorectal cancer therapy
  83. Electrochemical and AFM Characterization of G-Quadruplex Electrochemical Biosensors and Applications
  84. Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
  85. Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes
  86. Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling
  87. AS1411-decorated niosomes as effective nanocarriers for Ru(iii)-based drugs in anticancer strategies
  88. Lipid-Oligonucleotide Conjugates Forming G-Quadruplexes (Lipoquads) as Potent Inhibitors of HIV Entry
  89. i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene
  90. DNA-Origami-Aided Lithography for Sub-10 Nanometer Pattern Printing
  91. Biochemistry of RNA Silencing
  92. Cover Picture: Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues (ChemBioChem 12/2017)
  93. Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties
  94. Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues
  95. The effect of l -thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures
  96. Erratum: Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
  97. Antiviral activity of lipid-DNA molecules
  98. DNA-Origami-Driven Lithography for Patterning on Gold Surfaces with Sub-10 nm Resolution
  99. Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels
  100. Cationic nioplexes-in-polysaccharide-based hydrogels as versatile biodegradable hybrid materials to deliver nucleic acids
  101. Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms
  102. The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biological properties of oligonucleotides
  103. Meet Our Editorial Board Member
  104. Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA
  105. Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
  106. The role of helper lipids in the intracellular disposition and transfection efficiency of niosome formulations for gene delivery to retinal pigment epithelial cells
  107. The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA
  108. siRNA and RNAi optimization
  109. The influence of the polar head-group of synthetic cationic lipids on the transfection efficiency mediated by niosomes in rat retina and brain
  110. Biodegradable liposome-encapsulated hydrogels for biomedical applications: a marriage of convenience
  111. Cellular uptake studies of antisense oligonucleotides using G-quadruplex-nanostructures. The effect of cationic residue on the biophysical and biological properties
  112. Nioplexes encapsulated in supramolecular hybrid biohydrogels as versatile delivery platforms for nucleic acids
  113. Understanding the effect of the nature of the nucleobase in the loops on the stability of the i-motif structure
  114. Label-free electrochemical DNA sensor using “click”-functionalized PEDOT electrodes
  115. Sensitive and label-free detection of miRNA-145 by triplex formation
  116. Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers
  117. 1-[2,3-Bis(tetradecyloxy)propyl]-3-[2-(piperazin-1-yl)ethyl]urea
  118. New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
  119. Synthesis of oligonucleotides carrying fluorescently labelled O6-alkylguanine for measuring hAGT activity
  120. RNA modified with acyclic threoninol nucleic acids for RNA interference
  121. Protamine/DNA/Niosome Ternary Nonviral Vectors for Gene Delivery to the Retina: The Role of Protamine
  122. Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences
  123. Modulation of the RNA Interference Activity Using Central Mismatched siRNAs and Acyclic Threoninol Nucleic Acids (aTNA) Units
  124. Glucose Conjugation of Anti-HIV-1 Oligonucleotides Containing Unmethylated CpG Motifs Reduces Their Immunostimulatory Activity
  125. Niosomes based on synthetic cationic lipids for gene delivery: the influence of polar head-groups on the transfection efficiency in HEK-293, ARPE-19 and MSC-D1 cells
  126. Novel non-viral gene delivery systems composed of carbosilane dendron functionalized nanoparticles prepared from nano-emulsions as non-viral carriers for antisense oligonucleotides
  127. The effect of a cytidine derivative on the stability of intramolecular i-motifs was investigated.
  128. RNA/aTNA Chimeras: RNAi Effects and Nucleases Resistance of Single and Double Stranded RNAs
  129. Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles
  130. Cationic vesicles based on non-ionic surfactant and synthetic aminolipids mediate delivery of antisense oligonucleotides into mammalian cells
  131. DNA Nanoarchitectures: Steps towards Biological Applications
  132. Quadruplex Nanostructures of d(TGGGGT): Influence of Sodium and Potassium Ions
  133. Oligonucleotide delivery: a patent review (2010 – 2013)
  134. Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water
  135. Direct Covalent Attachment of DNA Microarrays by Rapid Thiol–Ene “Click” Chemistry
  136. A Novel Formulation Based on 2,3-Di(tetradecyloxy)propan-1-amine Cationic Lipid Combined with Polysorbate 80 for Efficient Gene Delivery to the Retina
  137. to fold or to dimerize a dilema for modified TBA
  138. Fundamental aspects of the nucleic acid i-motif structures
  139. A novel cationic niosome formulation for gene delivery to the retina
  140. Challenges and Opportunities for Oligonucleotide-Based Therapeutics by Antisense and RNA Interference Mechanisms
  141. Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops
  142. Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells
  143. Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates
  144. DNA Origami as a DNA Repair Nanosensor at the Single-Molecule Level
  145. Electrostatic Binding and Hydrophobic Collapse of Peptide–Nucleic Acid Aggregates Quantified Using Force Spectroscopy
  146. Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
  147. Efficient Self-Assembly in Water of Long Noncovalent Polymers by Nucleobase Analogues
  148. Functionalization of the 3′-Ends of DNA and RNA Strands with N-ethyl-N-coupled Nucleosides: A Promising Approach To Avoid 3′-Exonuclease-Catalyzed Hydrolysis of Therapeutic Oligonucleotides
  149. Carbohydrate-DNA Interactions at G-Quadruplexes: Folding and Stability Changes by Attaching Sugars at the 5′-End
  150. The detection of a protein involved in coagulation using fluorescence
  151. Self-assembled G-quadruplex nanostructures: AFM and voltammetric characterization
  152. Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions
  153. 20 Supramolecular polymerization of nucleobase-like monomers in water
  154. Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene
  155. Oligonucleotide-Peptide Conjugates: Solid-Phase Synthesis under Acidic Conditions and Use in ELISA Assays
  156. Synthesis of Steroid–Oligonucleotide Conjugates for a DNA Site-Encoded SPR Immunosensor
  157. Receptor-Based Virtual Screening and Biological Characterization of Human Apurinic/Apyrimidinic Endonuclease (Ape1) Inhibitors
  158. Synthesis of Oligonucleotides Carrying Thiol Groups Using a Simple Reagent Derived from Threoninol
  159. Development of an impedimetric DNA-biosensor based on layered double hydroxide for the detection of long ssDNA sequences
  160. The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer
  161. Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives
  162. Impact of Methylation on the Physical Properties of DNA
  163. Structure of Triplex DNA in the Gas Phase
  164. Synthesis and Structural Characterization of Stable Branched DNA G-Quadruplexes Using the Trebler Phosphoramidite
  165. Synthesis and in vitro inhibition properties of oligonucleotide conjugates carrying amphipathic proline-rich peptide derivatives of the sweet arrow peptide (SAP)
  166. Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications
  167. Synthesis and in vitro Inhibition Properties of siRNA Conjugates Carrying Acridine and Quindoline Moieties
  168. Functionally Enhanced siRNA Targeting TNFα Attenuates DSS-induced Colitis and TLR-mediated Immunostimulation in Mice
  169. Facile Modification of Silica Substrates Provides a Platform for Direct‐Writing Surface Click Chemistry
  170. Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method
  171. Apolar carbohydrates as DNA capping agents
  172. Interstrand interactions on DNA duplexes modified by TTF units at the 3′ or 5′-ends
  173. Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5′-(C3TA2)4-3′ sequence of the human telomere
  174. Use of Oligonucleotides Carrying Photolabile Groups for the Control of the Deposition of Nanoparticles in Surfaces and Nanoparticle Association
  175. Functionalization of Surfaces with Synthetic Oligonucleotides
  176. Functionalization and Self-Assembly of DNA Bidimensional Arrays
  177. Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures
  178. A Direct, Efficient Method for the Preparation of siRNAs Containing Ribo-likeNorthBicyclo[3.1.0]hexane Pseudosugars
  179. Synthesis and Properties of Oligodeoxynucleotides Carrying 2-Aminopurine
  180. Evaluation of the structure–activity relationship of thrombin with thrombin binding aptamers by voltammetry and atomic force microscopy
  181. Effect of North Bicyclo[3.1.0]hexane 2′-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification
  182. Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/π Interactions
  183. Synthesis of Lipid-Oligonucleotide Conjugates for RNA Interference Studies
  184. Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
  185. Branched RNA: A New Architecture for RNA Interference
  186. Synthesis of Oligonucleotide–Peptide Conjugates for Biomedical and Technological Applications
  187. Synthesis and properties of small interfering RNA duplexes carrying 5-ethyluridine residues
  188. Synthesis and structural properties of oligonucleotides covalently linked to acridine and quindoline derivatives through a threoninol linker
  189. Chemical equilibria studies using multivariate analysis methods
  190. Synthesis of Oligonucleotides Carrying Amino Lipid Groups at the 3′-End for RNA Interference Studies
  191. Synthesis and Properties of Oligonucleotides Carrying Isoquinoline Imidazo[1,2-a]azine Fluorescent Units
  192. Solid-Phase Synthesis of Oligodeoxynucleotides Containing N4-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine Moieties
  193. Synthesis, Cell-Surface Binding, and Cellular Uptake of Fluorescently Labeled Glucose−DNA Conjugates with Different Carbohydrate Presentation
  194. Stepwise synthesis of oligonucleotide–peptide conjugates containing guanidinium and lipophilic groups in their 3′-termini
  195. Spectrometric study of the oligodeoxyribonucleotide protonation in aqueous solution
  196. Fabrication of patterned surfaces by photolithographic exposure of DNA hairpins carrying a novel photolabile group
  197. Triplex-Stabilizing Properties of Parallel Clamps Carrying LNA Derivatives at theHoogsteenStrand
  198. Modified siRNAs for the study of the PAZ domain
  199. Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection ofO6-Alkylguanine-DNA Alkyltransferase Activity
  200. G-Quadruplex Nucleic Acids
  201. Structural Properties of G,T-Parallel Duplexes
  202. Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers
  203. Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization
  204. pH-Modulated Watson–Crick Duplex–Quadruplex Equilibria of Guanine-Rich and Cytosine-Rich DNA Sequences 140 Base Pairs Upstream of thec-kitTranscription Initiation Site
  205. Modified Oligonucleotides for Biosensing Applications
  206. Unique Tautomeric and Recognition Properties of Thioketothymines?
  207. DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site
  208. α,γ-Peptide Nanotube Templating of One-Dimensional Parallel Fullerene Arrangements
  209. Assembly of Two-Dimensional DNA Crystals CarryingN4-[2-(tert-Butyldisulfanyl)ethyl]cytosine Residues
  210. Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer
  211. Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand
  212. Fluorescence site-encoded DNA addressable hapten microarray for anabolic androgenic steroids
  213. Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra
  214. Photocleavage of Peptides and Oligodeoxynucleotides Carrying 2-Nitrobenzyl Groups
  215. Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies
  216. Synthesis and Hybridization Properties of Modified Oligodeoxynucleotides Carrying Non-Natural Bases
  217. Amino-acids condensations in the preparation of Nα-9-fluorenylrnethyloxycarbonylamino-acids with 9-fluorenylmethylchloroformate
  218. Experimental Measurement of Carbohydrate-Aromatic Stacking in Water by Using a Dangling-Ended DNA Model System
  219. Study of the interaction between the G-quadruplex-forming thrombin-binding aptamer and the porphyrin 5,10,15,20-tetrakis-(N-methyl-4-pyridyl)-21,23H-porphyrin tetratosylate
  220. Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbones
  221. Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones
  222. Incorporation of Zebularine from its 2′-Deoxyribonucleoside Triphosphate Derivative and Activity as a Template-Coding Nucleobase
  223. 8-Amino guanine accelerates tetramolecular G-quadruplex formation
  224. Synthesis of Oligonucleotide Derivatives Using ChemMatrix Supports
  225. Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter
  226. Synthesis of Oligonucleotides Carrying 5′-5′ Linkages Using Copper-Catalyzed Cycloaddition Reactions
  227. A Flexible Method for the Fabrication of Gold Nanostructures Using Oligonucleotide Derivatives
  228. New developments in the synthesis of oligonucleotide-peptide conjugates
  229. Triplex Formation Using Oligonucleotide Clamps Carrying 8-Aminopurines
  230. ds-Oligonucleotide–Peptide Conjugates Featuring Peptides from the Leucine-Zipper Region of Fos as Switchable Receptors for the Oncoprotein Jun
  231. Analysis of Interaction between Dendriplexes and Bovine Serum Albumin
  232. Water-Soluble Carbosilane Dendrimers: Synthesis Biocompatibility and Complexation with Oligonucleotides; Evaluation for Medical Applications
  233. Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins
  234. First Characterization of a Biosensor for Large DNA Molecules using Quartz Crystal Microbalance and Impedance Spectroscopy
  235. Solid-Phase Synthesis of Modified Oligonucleotides
  236. Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the central base sequences -XGCY- and -XGGCCY- using multivariate methods
  237. Erratum
  238. Trimethylguanosine Nucleoside Inhibits Cross-Linking Between Snurportin 1 and m3G-CAPPED U1 snRNA
  239. Efficient Sequence-Specific Purification of Listeria innocua mRNA Species by Triplex Affinity Capture with Parallel Tail-Clamps
  240. Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand
  241. DNA-templated assembly of nanoscale architectures for next-generation electronic devices
  242. Strand Displacement of Double-Stranded DNA by Triplex-Forming Antiparallel Purine-Hairpins
  243. Destabilization of Quadruplex DNA by 8-Aminoguanine
  244. Magnetically Trigged Direct Electrochemical Detection of DNA Hybridization Using Au67Quantum Dot as Electrical Tracer
  245. Toward an ICPMS-Linked DNA Assay Based on Gold Nanoparticles Immunoconnected through Peptide Sequences
  246. A Straightforward Synthesis of 5‘-Peptide Oligonucleotide Conjugates UsingNα-Fmoc-Protected Amino Acids
  247. DNA-templated assembly of nanoscale architectures
  248. “Parallel” and “Antiparallel Tail-Clamps” Increase the Efficiency of Triplex Formation with Structured DNA and RNA Targets
  249. Synthesis and Triplex-Forming Properties of Cyclic Oligonucleotides with (G,A)-Antiparallel Strands
  250. Hybridization and Melting Behavior of Peptide Nucleic Acid (PNA) Oligonucleotide Chimeras Conjugated to Gold Nanoparticles
  251. DNA-Templated Assembly of a Protein-Functionalized Nanogap Electrode
  252. Synthesis of OligonucleotidePeptide Conjugates Carrying the c-myc Peptide Epitope as Recognition System
  253. Synthesis and Triple-Helix-Stabilization Properties of Branched Oligonucleotides Carrying 8-Aminoadenine Moieties
  254. Synthesis and Properties of Oligonucleotides Carrying Cryptolepine Derivatives
  255. Synthesis of Oligoribonucleotides Containing 4‐Thiouridine Using the Convertible Nucleoside Approach and the 1‐(2‐Fluorophenyl)‐4‐Methoxypiperidin‐4‐yl Group
  256. Transgenic Rice Plants Expressing the Antifungal AFP Protein from Aspergillus Giganteus Show Enhanced Resistance to the Rice Blast Fungus Magnaporthe Grisea
  257. Antiparallel Triple Helices. Structural Characteristics and Stabilization by 8-Amino Derivatives
  258. Potent Inhibition ofHhaI DNA Methylase by the Aglycon of 2-(1H)-Pyrimidinone Riboside (Zebularine) at the GCGC Recognition Domain
  259. Properties of Triple Helices Formed by Oligonucleotides Containing 8-Aminopurines
  260. Synthesis of Branched Oligonucleotides as Templates for the Assembly of Nanomaterials
  261. Convenient Synthesis of 8-Amino-2′-deoxyadenosine
  262. Peptide–PNA Conjugates: Targeted Transport of Antisense Therapeutics into Tumors
  263. Imaging the DNA and nanoparticle components of a self-assembled nanoscale architecture
  264. Synthesis of labelled PNA oligomers by a post-synthetic modification approach
  265. Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2?-deoxyzebularine
  266. DNA-Controlled Assembly of Protein-Modified Gold Nanocrystals
  267. Synthesis and properties of radiolabeled CPTA-oligonucleotides
  268. Nanotechnology: Carbon nanotubes with DNA recognition
  269. DNA triple helices and biomedicine
  270. Biofunctionalization of Silica-Coated CdTe and Gold Nanocrystals
  271. Inhibition of HhaI DNA (Cytosine-C5) Methyltransferase by Oligodeoxyribonucleotides Containing 5-Aza-2′-deoxycytidine: Examination of the Intertwined Roles of Co-factor, Target, Transition State Structure and Enzyme Conformation
  272. Additional Binding Sites for Anionic Phospholipids and Calcium Ions in the Crystal Structures of Complexes of the C2 Domain of Protein Kinase Cα
  273. Iodouracil-mediated photocrosslinking of DNA to EcoRII restriction endonuclease in catalytic conditions
  274. Hoogsteen-Based Parallel-Stranded Duplexes of DNA. Effect of 8-Amino-purine Derivatives
  275. Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides
  276. Parallel-stranded hairpins containing 8-aminopurines. novel efficient probes for triple-helix formation
  277. SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING 8-BROMO-2′-DEOXYGUANOSINE
  278. AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES
  279. Preparation and Evaluation of Tumor-Targeting Peptide−Oligonucleotide Conjugates
  280. Synthesis and Hybridization Properties of DNA–PNA Chimeras Carrying 5-Bromouracil and 5-Methylcytosine
  281. Intracellular distribution of digoxigenin-labeled phosphorothioate oligonucleotides
  282. Synthesis and Binding Properties of Oligonucleotides Carrying Nuclear Localization Sequences
  283. “Action-at-a-Distance” Mutagenesis
  284. Theoretical calculations, synthesis and base pairing properties of oligonucleotides containing 8-amino-2'-deoxyadenosine
  285. The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator
  286. Synthesis of Oligodeoxynucleotides ContainingN4-Mercaptoethylcytosine and Their Use in the Preparation of Oligonucleotide−Peptide Conjugates Carrying c-mycTag-Sequence
  287. Triple helix stabilization properties of oligonucleotides containing 8-amino-2′-deoxyguanosine
  288. Biochemical basis of SOS-induced mutagenesis in Escherichia coli : Reconstitution of in vitro lesion bypass dependent on the UmuD′ 2 C mutagenic complex an...
  289. Exonuclease−Polymerase Active Site Partitioning of Primer−Template DNA Strands and Equilibrium Mg2+Binding Properties of Bacteriophage T4 DNA Polymerase†
  290. A Second-Step Splicing Activity Is Conserved from Yeast to Human
  291. 2′-O-Propargyl oligoribonucleotides: Synthesis and hybridisation
  292. Tandem 5′-GA:GA-3′ mismatches account for the high stability of the fold-back structures formed by the centromeric Drosophila dodeca-satellite 1 1Edited by I. Tinoco
  293. Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine
  294. Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras
  295. Initiation of replication of plasmid pMV158: mechanisms of DNA strand-transfer reactions mediated by the initiator RepB protein
  296. A simple method for the synthesis of 2′-O-alkylguanosine derivatives
  297. Abasic Translesion Synthesis by DNA Polymerase β Violates the “A-rule”
  298. New carbamate supports for the preparation of 3′-amino-modified oligonucleotides
  299. Synthesis of 1,2-diacyl-sn-glycerophosphadidylserine from egg phosphatidylcholine by phosphoramidite Methodology
  300. NMR Study of the Conformation of the 2-Aminopurine:Cytosine Mismatch in DNA†
  301. Spectroscopic and Calorimetric Characterizations of DNA Duplexes Containing 2-Aminopurine†
  302. Divalent Zinc Cations Induce the Formation of Two Distinct Homoduplexes of a d(GA)20 DNA Sequence
  303. Preparation and properties of oligodeoxynucleotides containing 4-O-butylthymine, 2-fluorohypoxanthine and 5-azacytosine1
  304. Preparation of oligonucleotide-dexamethasone conjugates
  305. Preparation of Oligonucleotides Containing Non-natural Base Analogues
  306. Dam methylase fromEscherichia coli: kinetic studies using modified DNA oligomers: hemimethylated substrates
  307. Digoxigenin-Labeled Phosphorothioate Oligonucleotides: A New Tool for the Study of Cellular Uptake
  308. Synthesis and properties of oligonucleotides containing the mutagenic base O4-benzylthymidine
  309. Use of NPE-Protecting Groups for the Preparation of Oligonucleotides Without Using Nucleophiles During the Final Deprotection
  310. Use of oligonucleotide-alkaline phosphatase conjugates as non-radioactive probes for rapid analysis of a proteinase inhibitor gene fromZea mays
  311. Nucleotide Insertion and Primer Extension at Abasic Template Sites in Different Sequence Contexts
  312. Pre-Steady-State Kinetic Analysis of Sequence-Dependent Nucleotide Excision by the 3'-Exonuclease Activity of Bacteriophage T4 DNA Polymerase
  313. Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258
  314. Chemical synthesis of a fully active transcriptional repressor protein.
  315. Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids
  316. Synthesis of Oligodeoxyribonucleotides Containing 2,6-Diaminopurine
  317. Criteria for the economic large scale solid-phase synthesis of oligonucleotides
  318. Solid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids
  319. A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides
  320. Gel-phase 31P-NMR. A new analytical tool to evaluate solid phase oligonucleoside synthesis.
  321. Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence
  322. Detection of hepatitis B virus DNA in human serumsamples: Use of digoxigenin-labeled oligonucleotides as modified primers for the polymerase chain reaction
  323. -2-(2,4-dinitrophenyl)ethyloxycarbonyl-amino acids, new base labile protected derivatives suitable for solid-phase peptide synthesis.
  324. S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis
  325. A synthetic procedure for the preparation of oligonucleotides without using ammonia and its application for the synthesis of oligonucleotides containing 0-4-alkyl thymidines.
  326. Preparation of oligonucleotides containing dAICA using an unexpected side-reaction observed on a protected derivative of 2-aza-2′-deoxyinosine.
  327. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides II. Synthesis of protected peptides
  328. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides I : Synthesis of the supports and their application to oligonucleotide synthesis.
  329. Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence.
  330. Syhthesis of Oligonucleotides Containing 4-0-Ethylthymidine
  331. O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides
  332. Synthesis and characterization of oligodeoxynucleotides containing the mutagenic base analogue 4-O-ethylthymine
  333. Characterization of the high pH wobble structure of the 2-aminopurine·cytosine mismatch by N-15 NMR spectroscopy
  334. Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions
  335. Structural and Dynamic Properties of a Bromouracil-Adenine Base Pair in DNA Studied by Proton NMR
  336. NMR studies of the stable mismatch purine-thymine in the self-complementary d(CGPuAATTTCG) duplex in solution
  337. NMR studies on an oligodeoxynucleotide containing 2-aminopurine opposite adenine
  338. Synthesis of Oligonucleotides Containing the Abasic Site Model Compound 1,4-Anhydro-2-Deoxy-D-Ribitol
  339. An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations
  340. On the use of s-t-butylsulphenyl group for protection of cysteine in solid-phase peptide synthesis using fmoc-amino acids
  341. Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR.
  342. Convergent solid phase peptide synthesis-III
  343. Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine
  344. Synthesis and properties of oligonucleotides containing 2′-deoxynebularine and 2′-deoxyxanthosine
  345. Diketopiperazine formation in acetamido-and nitrobenzamido-bridgedpolymeric supports.