All Stories

  1. Stabilizing DNA origami nanostructures for clinical translation through chemical and computational engineering
  2. Covalent functionalization of polymeric nanoparticles prepared from nano-emulsion templates for gene silencing and antioxidant delivery at neuronal level
  3. Conjugation strategy shapes antitumor efficacy and enables dose-sparing in non-antibody protein nanoconjugates
  4. Enhanced i‐Motif Stability through Consecutive 2′,2′‐Difluorocytidine Incorporation
  5. The Effect of 2′F-RNA on I-Motif Structure and Stability
  6. Resolution of complex mixtures of duplex and antiparallel triplex DNA structures by capillary electrophoresis and multivariate analysis
  7. Unraveling the Amplification-Free Quantitative Detection of Viral RNA in Nasopharyngeal Swab Samples Using a Compact Electrochemical Rapid Test Device
  8. Modified Bis-pyrimidine Clamps for Triplex Formation and Their Use in SARS-CoV-2 Detection
  9. Targeted Tumor Microenvironment Delivery of Floxuridine Prodrug via Soluble Silica Nanoparticles in Malignant Melanoma as a Model for Aggressive Cancer Treatment
  10. On the interaction of anticancer G-quadruplex ligands with GalNAc-functionalized G-quadruplex-forming carriers for selective recognition and treatment of hepatocellular carcinoma
  11. Targeted Tumor Microenvironment Delivery of Floxuridine ProdrugviaSoluble Silica Nanoparticles in Malignant Melanoma as a Model for Aggressive Cancer Treatment
  12. Assessment of methodologies based on the formation of antiparallel triplex DNA structures and fluorescent silver nanoclusters for the detection of pyrimidine-rich sequences
  13. Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism
  14. Manual and automated synthesis of modified oligonucleotides on core–shell solid supports
  15. Aptamer-Hytac Chimeras for Targeted Degradation of SARS-CoV-2 Spike-1
  16. Polypurine Reverse Hoogsteen hairpins as a therapeutic tool for SARS-CoV-2 infection
  17. Surface decoration of PLGA nanoparticles enables efficient transport of floxuridine oligomers into mammalian cells
  18. The synthesis of solid supports carrying base labile linkers to generate 3′-phosphate oligonucleotides
  19. DNA-directed immobilization fluorescent immunoarray for multiplexed antibiotic residue determination in milk
  20. Engineering ternary systems as non-viral vehicles for transporting floxuridine oligomer
  21. Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives
  22. Biophysical evaluation of antiparallel triplexes for biosensing and biomedical applications
  23. Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration
  24. Single‐Step Functionalization Strategy of Graphene Microtransistor Array with Chemically Modified Aptamers for Biosensing Applications
  25. Synthesis and Evaluation of 3′-Oleyl–Oligonucleotide Conjugates as Potential Cellular Uptake Enhancers
  26. Synthesis of 2′-O-Methyl/2′-O-MOE-L-Nucleoside Derivatives and Their Applications: Preparation of G-Quadruplexes, Their Characterization, and Stability Studies
  27. Special Issue “Frontiers in Nucleic Acid Chemistry—In Memory of Professor Enrique Pedroso for His Outstanding Contributions to Nucleic Acid Chemistry”
  28. Rapid and Highly Efficient Separation of i-Motif DNA Species by CE-UV and Multivariate Curve Resolution
  29. Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs)
  30. Detection of pyrimidine-rich DNA sequences based on the formation of parallel and antiparallel triplex DNA and fluorescent silver nanoclusters
  31. Exploring the stabilizing effect on the i-motif of neighboring structural motifs and drugs
  32. Stability of polymeric cationic niosomes and their plasmid DNA-based complexes as gene delivery carriers
  33. Evaluation of Poly(N-Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells
  34. Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs
  35. Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies
  36. Correction: Clua et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules 2022, 27, 3944
  37. Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)
  38. Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region
  39. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes
  40. Cover Picture: Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications (Chem. Rec. 4/2022)
  41. A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model
  42. Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications
  43. Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency
  44. Investigation of the Complexes Formed between PARP1 Inhibitors and PARP1 G-Quadruplex at the Gene Promoter Region
  45. Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines
  46. Biodistribution of 68/67Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging
  47. Exploring the Interaction of Curaxin CBL0137 with G-Quadruplex DNA Oligomers
  48. The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis
  49. Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake
  50. Structural Effects of Incorporation of 2'‐Deoxy‐2'2'‐Difluorodeoxycytidine (Gemcitabine) in A‐ and B‐Form Duplexes
  51. Parallel G-quadruplex Structures Increase Cellular Uptake and Cytotoxicity of 5-Fluoro-2′-deoxyuridine Oligomers in 5-Fluorouracil Resistant Cells
  52. Biomedical Applications of DNA-nanostructures
  53. EcoRII Restriction Endonuclease Forms Specific Contacts to the Bases of Its Target Sequence Flipped from DNA in a Transition Complex with Photoactivatable Substrates
  54. G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide
  55. Oligonucleotides Containing 1-Aminomethyl or 1-Mercaptomethyl-2-deoxy-d-ribofuranoses: Synthesis, Purification, Characterization, and Conjugation with Fluorophores and Lipids
  56. Nanoparticles for Brain Drug Delivery
  57. Nucleic Acids Chemistry
  58. Preparation of Lipid-Conjugated siRNA Oligonucleotides for Enhanced Gene Inhibition in Mammalian Cells
  59. Studies on the interactions of Ag(i) with DNA and their implication on the DNA-templated synthesis of silver nanoclusters and on the interaction with complementary DNA and RNA sequences
  60. Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles
  61. Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery
  62. Developing Protein–Antitumoral Drug Nanoconjugates as Bifunctional Antimicrobial Agents
  63. Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples
  64. Study of alkaloid berberine and its interaction with the human telomeric i-motif DNA structure
  65. Sorting hidden patterns in nanoparticle performance for glioblastoma using machine learning algorithms
  66. Non-viral mediated gene therapy in human cystic fibrosis airway epithelial cells recovers chloride channel functionality
  67. Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter region of the SMARCA4 gene
  68. Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins
  69. Fast and Accurate Pneumocystis Pneumonia Diagnosis in Human Samples Using a Label-Free Plasmonic Biosensor
  70. Brain Angiogenesis Induced by Nonviral Gene Therapy with Potential Therapeutic Benefits for Central Nervous System Diseases
  71. Niosome-Based Approach for In Situ Gene Delivery to Retina and Brain Cortex as Immune-Privileged Tissues
  72. Ethylcellulose nanoparticles as a new “in vitro” transfection tool for antisense oligonucleotide delivery
  73. Sulfonamide as amide isostere for fine-tuning the gelation properties of physical gels
  74. Liposomes‐ in ‐Chitosan Hydrogels: Challenges and Opportunities for Biomedical Applications
  75. Alginate Hydrogels as Scaffolds and Delivery Systems to Repair the Damaged Spinal Cord
  76. A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor
  77. Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41
  78. Aptamer-peptide conjugates as a new strategy to modulate human α-thrombin binding affinity
  79. Cationic niosome-based hBMP7 gene transfection of neuronal precursor NT2 cells to reduce the migration of glioma cells in vitro
  80. Study of conformational transitions of i-motif DNA using time-resolved fluorescence and multivariate analysis methods
  81. Gene delivery to the rat retina by non-viral vectors based on chloroquine-containing cationic niosomes
  82. The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry
  83. Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
  84. On the Race for More Stretchable and Tough Hydrogels
  85. Parallel Clamps and Polypurine Hairpins (PPRH) for Gene Silencing and Triplex‐Affinity Capture: Design, Synthesis, and Use
  86. Efficient bioactive oligonucleotide‐protein conjugation for cell‐targeted cancer therapy
  87. Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
  88. Expanding the limits of amide–triazole isosteric substitution in bisamide-based physical gels
  89. Overview of DNA Self-Assembling: Progresses in Biomedical Applications
  90. Detection of a microRNA involved in human disease
  91. Detection of DNA methylation
  92. Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles
  93. Synthesis of Oligonucleotides Carrying Nucleic Acid Derivatives of Biomedical and Structural Interest
  94. Successful evaluation of a nanodrug against metastasis
  95. Preparation of new compounds with interesting porperties in biomedicine
  96. siRNA Modified with 2′-Deoxy-2′-C -methylpyrimidine Nucleosides
  97. Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques
  98. Synthesis, Characterization, and Self-Assembly of a Tetrathiafulvalene (TTF)–Triglycyl Derivative
  99. Isosteric Substitution of 4H-1,2,4-Triazole by 1H-1,2,3-Triazole in Isophthalic Derivative Enabled Hydrogel Formation for Controlled Drug Delivery
  100. Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates
  101. Stem cell-based gene delivery mediated by cationic niosomes for bone regeneration
  102. Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study
  103. DNA-based nanoscaffolds as vehicles for 5-fluoro-2′-deoxyuridine oligomers in colorectal cancer therapy
  104. Electrochemical and AFM Characterization of G-Quadruplex Electrochemical Biosensors and Applications
  105. Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
  106. Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes
  107. Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling
  108. AS1411-decorated niosomes as effective nanocarriers for Ru(iii)-based drugs in anticancer strategies
  109. Lipid-Oligonucleotide Conjugates Forming G-Quadruplexes (Lipoquads) as Potent Inhibitors of HIV Entry
  110. i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene
  111. DNA-Origami-Aided Lithography for Sub-10 Nanometer Pattern Printing
  112. Biochemistry of RNA Silencing
  113. Cover Picture: Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues (ChemBioChem 12/2017)
  114. Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties
  115. Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues
  116. The effect of l -thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures
  117. Erratum: Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
  118. Antiviral activity of lipid-DNA molecules
  119. DNA-Origami-Driven Lithography for Patterning on Gold Surfaces with Sub-10 nm Resolution
  120. Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels
  121. Cationic nioplexes-in-polysaccharide-based hydrogels as versatile biodegradable hybrid materials to deliver nucleic acids
  122. Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms
  123. The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biological properties of oligonucleotides
  124. Meet Our Editorial Board Member
  125. Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA
  126. Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
  127. The role of helper lipids in the intracellular disposition and transfection efficiency of niosome formulations for gene delivery to retinal pigment epithelial cells
  128. The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA
  129. siRNA and RNAi optimization
  130. The influence of the polar head-group of synthetic cationic lipids on the transfection efficiency mediated by niosomes in rat retina and brain
  131. Biodegradable liposome-encapsulated hydrogels for biomedical applications: a marriage of convenience
  132. Cellular uptake studies of antisense oligonucleotides using G-quadruplex-nanostructures. The effect of cationic residue on the biophysical and biological properties
  133. Nioplexes encapsulated in supramolecular hybrid biohydrogels as versatile delivery platforms for nucleic acids
  134. Understanding the effect of the nature of the nucleobase in the loops on the stability of the i-motif structure
  135. Label-free electrochemical DNA sensor using “click”-functionalized PEDOT electrodes
  136. Sensitive and label-free detection of miRNA-145 by triplex formation
  137. Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers
  138. 1-[2,3-Bis(tetradecyloxy)propyl]-3-[2-(piperazin-1-yl)ethyl]urea
  139. New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
  140. Synthesis of oligonucleotides carrying fluorescently labelled O6-alkylguanine for measuring hAGT activity
  141. RNA modified with acyclic threoninol nucleic acids for RNA interference
  142. Protamine/DNA/Niosome Ternary Nonviral Vectors for Gene Delivery to the Retina: The Role of Protamine
  143. Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences
  144. Modulation of the RNA Interference Activity Using Central Mismatched siRNAs and Acyclic Threoninol Nucleic Acids (aTNA) Units
  145. Glucose Conjugation of Anti-HIV-1 Oligonucleotides Containing Unmethylated CpG Motifs Reduces Their Immunostimulatory Activity
  146. Niosomes based on synthetic cationic lipids for gene delivery: the influence of polar head-groups on the transfection efficiency in HEK-293, ARPE-19 and MSC-D1 cells
  147. Novel non-viral gene delivery systems composed of carbosilane dendron functionalized nanoparticles prepared from nano-emulsions as non-viral carriers for antisense oligonucleotides
  148. The effect of a cytidine derivative on the stability of intramolecular i-motifs was investigated.
  149. RNA/aTNA Chimeras: RNAi Effects and Nucleases Resistance of Single and Double Stranded RNAs
  150. Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles
  151. Cationic vesicles based on non-ionic surfactant and synthetic aminolipids mediate delivery of antisense oligonucleotides into mammalian cells
  152. DNA Nanoarchitectures: Steps towards Biological Applications
  153. Quadruplex Nanostructures of d(TGGGGT): Influence of Sodium and Potassium Ions
  154. Oligonucleotide delivery: a patent review (2010 – 2013)
  155. Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water
  156. Direct Covalent Attachment of DNA Microarrays by Rapid Thiol–Ene “Click” Chemistry
  157. A Novel Formulation Based on 2,3-Di(tetradecyloxy)propan-1-amine Cationic Lipid Combined with Polysorbate 80 for Efficient Gene Delivery to the Retina
  158. to fold or to dimerize a dilema for modified TBA
  159. Fundamental aspects of the nucleic acid i-motif structures
  160. A novel cationic niosome formulation for gene delivery to the retina
  161. Challenges and Opportunities for Oligonucleotide-Based Therapeutics by Antisense and RNA Interference Mechanisms
  162. Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops
  163. Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells
  164. Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates
  165. DNA Origami as a DNA Repair Nanosensor at the Single-Molecule Level
  166. Electrostatic Binding and Hydrophobic Collapse of Peptide–Nucleic Acid Aggregates Quantified Using Force Spectroscopy
  167. Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
  168. Efficient Self-Assembly in Water of Long Noncovalent Polymers by Nucleobase Analogues
  169. Functionalization of the 3′-Ends of DNA and RNA Strands with N-ethyl-N-coupled Nucleosides: A Promising Approach To Avoid 3′-Exonuclease-Catalyzed Hydrolysis of Therapeutic Oligonucleotides
  170. Carbohydrate-DNA Interactions at G-Quadruplexes: Folding and Stability Changes by Attaching Sugars at the 5′-End
  171. The detection of a protein involved in coagulation using fluorescence
  172. Self-assembled G-quadruplex nanostructures: AFM and voltammetric characterization
  173. Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions
  174. 20 Supramolecular polymerization of nucleobase-like monomers in water
  175. Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene
  176. Oligonucleotide-Peptide Conjugates: Solid-Phase Synthesis under Acidic Conditions and Use in ELISA Assays
  177. Synthesis of Steroid–Oligonucleotide Conjugates for a DNA Site-Encoded SPR Immunosensor
  178. Receptor-Based Virtual Screening and Biological Characterization of Human Apurinic/Apyrimidinic Endonuclease (Ape1) Inhibitors
  179. Synthesis of Oligonucleotides Carrying Thiol Groups Using a Simple Reagent Derived from Threoninol
  180. Development of an impedimetric DNA-biosensor based on layered double hydroxide for the detection of long ssDNA sequences
  181. The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer
  182. Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives
  183. Impact of Methylation on the Physical Properties of DNA
  184. Structure of Triplex DNA in the Gas Phase
  185. Synthesis and Structural Characterization of Stable Branched DNA G-Quadruplexes Using the Trebler Phosphoramidite
  186. Synthesis and in vitro inhibition properties of oligonucleotide conjugates carrying amphipathic proline-rich peptide derivatives of the sweet arrow peptide (SAP)
  187. Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications
  188. Synthesis and in vitro Inhibition Properties of siRNA Conjugates Carrying Acridine and Quindoline Moieties
  189. Functionally Enhanced siRNA Targeting TNFα Attenuates DSS-induced Colitis and TLR-mediated Immunostimulation in Mice
  190. Facile Modification of Silica Substrates Provides a Platform for Direct‐Writing Surface Click Chemistry
  191. Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method
  192. Apolar carbohydrates as DNA capping agents
  193. Interstrand interactions on DNA duplexes modified by TTF units at the 3′ or 5′-ends
  194. Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5′-(C3TA2)4-3′ sequence of the human telomere
  195. Use of Oligonucleotides Carrying Photolabile Groups for the Control of the Deposition of Nanoparticles in Surfaces and Nanoparticle Association
  196. Functionalization of Surfaces with Synthetic Oligonucleotides
  197. Functionalization and Self-Assembly of DNA Bidimensional Arrays
  198. Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures
  199. A Direct, Efficient Method for the Preparation of siRNAs Containing Ribo-likeNorthBicyclo[3.1.0]hexane Pseudosugars
  200. Synthesis and Properties of Oligodeoxynucleotides Carrying 2-Aminopurine
  201. Evaluation of the structure–activity relationship of thrombin with thrombin binding aptamers by voltammetry and atomic force microscopy
  202. Effect of North Bicyclo[3.1.0]hexane 2′-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification
  203. Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/π Interactions
  204. Synthesis of Lipid-Oligonucleotide Conjugates for RNA Interference Studies
  205. Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
  206. Branched RNA: A New Architecture for RNA Interference
  207. Synthesis of Oligonucleotide–Peptide Conjugates for Biomedical and Technological Applications
  208. Synthesis and properties of small interfering RNA duplexes carrying 5-ethyluridine residues
  209. Synthesis and structural properties of oligonucleotides covalently linked to acridine and quindoline derivatives through a threoninol linker
  210. Chemical equilibria studies using multivariate analysis methods
  211. Synthesis of Oligonucleotides Carrying Amino Lipid Groups at the 3′-End for RNA Interference Studies
  212. Synthesis and Properties of Oligonucleotides Carrying Isoquinoline Imidazo[1,2-a]azine Fluorescent Units
  213. Solid-Phase Synthesis of Oligodeoxynucleotides Containing N4-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine Moieties
  214. Synthesis, Cell-Surface Binding, and Cellular Uptake of Fluorescently Labeled Glucose−DNA Conjugates with Different Carbohydrate Presentation
  215. Stepwise synthesis of oligonucleotide–peptide conjugates containing guanidinium and lipophilic groups in their 3′-termini
  216. Spectrometric study of the oligodeoxyribonucleotide protonation in aqueous solution
  217. Fabrication of patterned surfaces by photolithographic exposure of DNA hairpins carrying a novel photolabile group
  218. Triplex-Stabilizing Properties of Parallel Clamps Carrying LNA Derivatives at theHoogsteenStrand
  219. Modified siRNAs for the study of the PAZ domain
  220. Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection ofO6-Alkylguanine-DNA Alkyltransferase Activity
  221. G-Quadruplex Nucleic Acids
  222. Structural Properties of G,T-Parallel Duplexes
  223. Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers
  224. Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization
  225. pH-Modulated Watson–Crick Duplex–Quadruplex Equilibria of Guanine-Rich and Cytosine-Rich DNA Sequences 140 Base Pairs Upstream of thec-kitTranscription Initiation Site
  226. Modified Oligonucleotides for Biosensing Applications
  227. Unique Tautomeric and Recognition Properties of Thioketothymines?
  228. DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site
  229. α,γ-Peptide Nanotube Templating of One-Dimensional Parallel Fullerene Arrangements
  230. Assembly of Two-Dimensional DNA Crystals CarryingN4-[2-(tert-Butyldisulfanyl)ethyl]cytosine Residues
  231. Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer
  232. Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand
  233. Fluorescence site-encoded DNA addressable hapten microarray for anabolic androgenic steroids
  234. Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra
  235. Photocleavage of Peptides and Oligodeoxynucleotides Carrying 2-Nitrobenzyl Groups
  236. Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies
  237. Synthesis and Hybridization Properties of Modified Oligodeoxynucleotides Carrying Non-Natural Bases
  238. Amino-acids condensations in the preparation of Nα-9-fluorenylrnethyloxycarbonylamino-acids with 9-fluorenylmethylchloroformate
  239. Experimental Measurement of Carbohydrate-Aromatic Stacking in Water by Using a Dangling-Ended DNA Model System
  240. Study of the interaction between the G-quadruplex-forming thrombin-binding aptamer and the porphyrin 5,10,15,20-tetrakis-(N-methyl-4-pyridyl)-21,23H-porphyrin tetratosylate
  241. Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbones
  242. Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones
  243. Incorporation of Zebularine from its 2′-Deoxyribonucleoside Triphosphate Derivative and Activity as a Template-Coding Nucleobase
  244. 8-Amino guanine accelerates tetramolecular G-quadruplex formation
  245. Synthesis of Oligonucleotide Derivatives Using ChemMatrix Supports
  246. Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter
  247. Synthesis of Oligonucleotides Carrying 5′-5′ Linkages Using Copper-Catalyzed Cycloaddition Reactions
  248. A Flexible Method for the Fabrication of Gold Nanostructures Using Oligonucleotide Derivatives
  249. New developments in the synthesis of oligonucleotide-peptide conjugates
  250. Triplex Formation Using Oligonucleotide Clamps Carrying 8-Aminopurines
  251. ds-Oligonucleotide–Peptide Conjugates Featuring Peptides from the Leucine-Zipper Region of Fos as Switchable Receptors for the Oncoprotein Jun
  252. Analysis of Interaction between Dendriplexes and Bovine Serum Albumin
  253. Water-Soluble Carbosilane Dendrimers: Synthesis Biocompatibility and Complexation with Oligonucleotides; Evaluation for Medical Applications
  254. Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins
  255. First Characterization of a Biosensor for Large DNA Molecules using Quartz Crystal Microbalance and Impedance Spectroscopy
  256. Solid-Phase Synthesis of Modified Oligonucleotides
  257. Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the central base sequences -XGCY- and -XGGCCY- using multivariate methods
  258. Erratum
  259. Trimethylguanosine Nucleoside Inhibits Cross-Linking Between Snurportin 1 and m3G-CAPPED U1 snRNA
  260. Efficient Sequence-Specific Purification of Listeria innocua mRNA Species by Triplex Affinity Capture with Parallel Tail-Clamps
  261. Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand
  262. DNA-templated assembly of nanoscale architectures for next-generation electronic devices
  263. Strand Displacement of Double-Stranded DNA by Triplex-Forming Antiparallel Purine-Hairpins
  264. Destabilization of Quadruplex DNA by 8-Aminoguanine
  265. Magnetically Trigged Direct Electrochemical Detection of DNA Hybridization Using Au67Quantum Dot as Electrical Tracer
  266. Toward an ICPMS-Linked DNA Assay Based on Gold Nanoparticles Immunoconnected through Peptide Sequences
  267. A Straightforward Synthesis of 5‘-Peptide Oligonucleotide Conjugates UsingNα-Fmoc-Protected Amino Acids
  268. DNA-templated assembly of nanoscale architectures
  269. “Parallel” and “Antiparallel Tail-Clamps” Increase the Efficiency of Triplex Formation with Structured DNA and RNA Targets
  270. Synthesis and Triplex-Forming Properties of Cyclic Oligonucleotides with (G,A)-Antiparallel Strands
  271. Hybridization and Melting Behavior of Peptide Nucleic Acid (PNA) Oligonucleotide Chimeras Conjugated to Gold Nanoparticles
  272. DNA-Templated Assembly of a Protein-Functionalized Nanogap Electrode
  273. Synthesis of OligonucleotidePeptide Conjugates Carrying the c-myc Peptide Epitope as Recognition System
  274. Synthesis and Triple-Helix-Stabilization Properties of Branched Oligonucleotides Carrying 8-Aminoadenine Moieties
  275. Synthesis and Properties of Oligonucleotides Carrying Cryptolepine Derivatives
  276. Synthesis of Oligoribonucleotides Containing 4‐Thiouridine Using the Convertible Nucleoside Approach and the 1‐(2‐Fluorophenyl)‐4‐Methoxypiperidin‐4‐yl Group
  277. Transgenic Rice Plants Expressing the Antifungal AFP Protein from Aspergillus Giganteus Show Enhanced Resistance to the Rice Blast Fungus Magnaporthe Grisea
  278. Antiparallel Triple Helices. Structural Characteristics and Stabilization by 8-Amino Derivatives
  279. Potent Inhibition ofHhaI DNA Methylase by the Aglycon of 2-(1H)-Pyrimidinone Riboside (Zebularine) at the GCGC Recognition Domain
  280. Properties of Triple Helices Formed by Oligonucleotides Containing 8-Aminopurines
  281. Synthesis of Branched Oligonucleotides as Templates for the Assembly of Nanomaterials
  282. Convenient Synthesis of 8-Amino-2′-deoxyadenosine
  283. Peptide–PNA Conjugates: Targeted Transport of Antisense Therapeutics into Tumors
  284. Imaging the DNA and nanoparticle components of a self-assembled nanoscale architecture
  285. Synthesis of labelled PNA oligomers by a post-synthetic modification approach
  286. Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2?-deoxyzebularine
  287. DNA-Controlled Assembly of Protein-Modified Gold Nanocrystals
  288. Synthesis and properties of radiolabeled CPTA-oligonucleotides
  289. Nanotechnology: Carbon nanotubes with DNA recognition
  290. DNA triple helices and biomedicine
  291. Biofunctionalization of Silica-Coated CdTe and Gold Nanocrystals
  292. Inhibition of HhaI DNA (Cytosine-C5) Methyltransferase by Oligodeoxyribonucleotides Containing 5-Aza-2′-deoxycytidine: Examination of the Intertwined Roles of Co-factor, Target, Transition State Structure and Enzyme Conformation
  293. Additional Binding Sites for Anionic Phospholipids and Calcium Ions in the Crystal Structures of Complexes of the C2 Domain of Protein Kinase Cα
  294. Iodouracil-mediated photocrosslinking of DNA to EcoRII restriction endonuclease in catalytic conditions
  295. Hoogsteen-Based Parallel-Stranded Duplexes of DNA. Effect of 8-Amino-purine Derivatives
  296. Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides
  297. Parallel-stranded hairpins containing 8-aminopurines. novel efficient probes for triple-helix formation
  298. SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING 8-BROMO-2′-DEOXYGUANOSINE
  299. AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES
  300. Preparation and Evaluation of Tumor-Targeting Peptide−Oligonucleotide Conjugates
  301. Synthesis and Hybridization Properties of DNA–PNA Chimeras Carrying 5-Bromouracil and 5-Methylcytosine
  302. Intracellular distribution of digoxigenin-labeled phosphorothioate oligonucleotides
  303. Synthesis and Binding Properties of Oligonucleotides Carrying Nuclear Localization Sequences
  304. “Action-at-a-Distance” Mutagenesis
  305. Theoretical calculations, synthesis and base pairing properties of oligonucleotides containing 8-amino-2'-deoxyadenosine
  306. The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator
  307. Synthesis of Oligodeoxynucleotides ContainingN4-Mercaptoethylcytosine and Their Use in the Preparation of Oligonucleotide−Peptide Conjugates Carrying c-mycTag-Sequence
  308. Triple helix stabilization properties of oligonucleotides containing 8-amino-2′-deoxyguanosine
  309. Biochemical basis of SOS-induced mutagenesis in Escherichia coli : Reconstitution of in vitro lesion bypass dependent on the UmuD′ 2 C mutagenic complex an...
  310. Exonuclease−Polymerase Active Site Partitioning of Primer−Template DNA Strands and Equilibrium Mg2+Binding Properties of Bacteriophage T4 DNA Polymerase†
  311. A Second-Step Splicing Activity Is Conserved from Yeast to Human
  312. 2′-O-Propargyl oligoribonucleotides: Synthesis and hybridisation
  313. Tandem 5′-GA:GA-3′ mismatches account for the high stability of the fold-back structures formed by the centromeric Drosophila dodeca-satellite 1 1Edited by I. Tinoco
  314. Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine
  315. Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras
  316. Initiation of replication of plasmid pMV158: mechanisms of DNA strand-transfer reactions mediated by the initiator RepB protein
  317. A simple method for the synthesis of 2′-O-alkylguanosine derivatives
  318. Abasic Translesion Synthesis by DNA Polymerase β Violates the “A-rule”
  319. New carbamate supports for the preparation of 3′-amino-modified oligonucleotides
  320. Synthesis of 1,2-diacyl-sn-glycerophosphadidylserine from egg phosphatidylcholine by phosphoramidite Methodology
  321. NMR Study of the Conformation of the 2-Aminopurine:Cytosine Mismatch in DNA†
  322. Spectroscopic and Calorimetric Characterizations of DNA Duplexes Containing 2-Aminopurine†
  323. Divalent Zinc Cations Induce the Formation of Two Distinct Homoduplexes of a d(GA)20 DNA Sequence
  324. Preparation and properties of oligodeoxynucleotides containing 4-O-butylthymine, 2-fluorohypoxanthine and 5-azacytosine1
  325. Preparation of oligonucleotide-dexamethasone conjugates
  326. Preparation of Oligonucleotides Containing Non-natural Base Analogues
  327. Dam methylase fromEscherichia coli: kinetic studies using modified DNA oligomers: hemimethylated substrates
  328. Digoxigenin-Labeled Phosphorothioate Oligonucleotides: A New Tool for the Study of Cellular Uptake
  329. Synthesis and properties of oligonucleotides containing the mutagenic base O4-benzylthymidine
  330. Use of NPE-Protecting Groups for the Preparation of Oligonucleotides Without Using Nucleophiles During the Final Deprotection
  331. Use of oligonucleotide-alkaline phosphatase conjugates as non-radioactive probes for rapid analysis of a proteinase inhibitor gene fromZea mays
  332. Nucleotide Insertion and Primer Extension at Abasic Template Sites in Different Sequence Contexts
  333. Pre-Steady-State Kinetic Analysis of Sequence-Dependent Nucleotide Excision by the 3'-Exonuclease Activity of Bacteriophage T4 DNA Polymerase
  334. Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258
  335. Chemical synthesis of a fully active transcriptional repressor protein.
  336. Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids
  337. Synthesis of Oligodeoxyribonucleotides Containing 2,6-Diaminopurine
  338. Criteria for the economic large scale solid-phase synthesis of oligonucleotides
  339. Solid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids
  340. A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides
  341. Gel-phase 31P-NMR. A new analytical tool to evaluate solid phase oligonucleoside synthesis.
  342. Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence
  343. Detection of hepatitis B virus DNA in human serumsamples: Use of digoxigenin-labeled oligonucleotides as modified primers for the polymerase chain reaction
  344. -2-(2,4-dinitrophenyl)ethyloxycarbonyl-amino acids, new base labile protected derivatives suitable for solid-phase peptide synthesis.
  345. S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis
  346. A synthetic procedure for the preparation of oligonucleotides without using ammonia and its application for the synthesis of oligonucleotides containing 0-4-alkyl thymidines.
  347. Preparation of oligonucleotides containing dAICA using an unexpected side-reaction observed on a protected derivative of 2-aza-2′-deoxyinosine.
  348. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides II. Synthesis of protected peptides
  349. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides I : Synthesis of the supports and their application to oligonucleotide synthesis.
  350. Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence.
  351. Syhthesis of Oligonucleotides Containing 4-0-Ethylthymidine
  352. O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides
  353. Synthesis and characterization of oligodeoxynucleotides containing the mutagenic base analogue 4-O-ethylthymine
  354. Characterization of the high pH wobble structure of the 2-aminopurine·cytosine mismatch by N-15 NMR spectroscopy
  355. Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions
  356. Structural and Dynamic Properties of a Bromouracil-Adenine Base Pair in DNA Studied by Proton NMR
  357. NMR studies of the stable mismatch purine-thymine in the self-complementary d(CGPuAATTTCG) duplex in solution
  358. NMR studies on an oligodeoxynucleotide containing 2-aminopurine opposite adenine
  359. Synthesis of Oligonucleotides Containing the Abasic Site Model Compound 1,4-Anhydro-2-Deoxy-D-Ribitol
  360. An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations
  361. On the use of s-t-butylsulphenyl group for protection of cysteine in solid-phase peptide synthesis using fmoc-amino acids
  362. Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR.
  363. Convergent solid phase peptide synthesis-III
  364. Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine
  365. Synthesis and properties of oligonucleotides containing 2′-deoxynebularine and 2′-deoxyxanthosine
  366. Diketopiperazine formation in acetamido-and nitrobenzamido-bridgedpolymeric supports.