Professor Morten Grötli
University of Gothenburg
Professor, Chemistry
Sweden
My co-authors include
Ramon Eritja
Prof. Morten Meldal
Professor Corey Nislow
My Publications
Towards the development of chromone-based MEK1/2 modulators
European Journal of Medicinal Chemistry
October 2014
8-Bromination of 2,6,9-trisubstituted purines with pyridinium tribromide
Tetrahedron Letters
April 2014
Application of a peptide-based assay to characterize inhibitors targeting protein kinas...
Current Genetics
March 2014
A Single-Cell Study of a Highly Effective Hog1 Inhibitor for in Situ Yeast Cell Manipul...
Micromachines
February 2014
Synthesis and photophysical characterisation of new fluorescent triazole adenine analogues
Organic & Biomolecular Chemistry
January 2014
Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably throug...
American Journal of Molecular Biology
January 2014
Synthesis and photophysical characterization of 1- and 4-(purinyl)triazoles
Tetrahedron
October 2013
Effect of MAPK Inhibitor on the Arsenite uptake by Aquaglyceroporin in Single Yeast Cells
January 2013
Design and evaluation of a microfluidic system for inhibition studies of yeast cell sig...
October 2012
Validation of regulated protein phosphorylation events in yeast by quantitative mass sp...
PROTEOMICS
September 2012
Proline-mediated formation of novel chroman-4-one tetrahydropyrimidines
Tetrahedron
September 2012
Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads...
Biochemical Journal
September 2012
Method for Activation and Recycling of Trityl Resins
The Journal of Organic Chemistry
August 2012
Solid-Phase Synthesis of 5′-O-[N-(Acyl)sulfamoyl]adenosine Derivatives
European Journal of Organic Chemistry
May 2012
Preparation of 3-Substituted-1-Isopropyl-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidin-4-am...
Journal of Medicinal Chemistry
May 2012
Investigation, optimization and synthesis of sulfamoyloxy-linked aminoacyl-AMP analogues
Tetrahedron
February 2012
Design, Synthesis, and Biological Evaluation of Chromone-Based p38 MAP Kinase Inhibitors
Journal of Medicinal Chemistry
September 2011
NMR-Based Substrate Analog Docking to Escherichia coli Peptidyl-tRNA Hydrolase
Journal of Molecular Biology
September 2011
Design, Synthesis and Characterization of a Highly Effective Inhibitor for Analog-Sensi...
PLoS ONE
June 2011
Design, Synthesis, and Characterization of a Highly Effective Hog1 Inhibitor: A Powerfu...
PLoS ONE
May 2011
Inhibitors and promoters of tubulin polymerization: Synthesis and biological evaluation...
Bioorganic & Medicinal Chemistry
April 2011
Characterization of photophysical and base-mimicking properties of a novel fluorescent ...
Nucleic Acids Research
January 2011
Positional Scanning Peptide Libraries for Kinase Substrate Specificity Determinations: ...
Journal of Combinatorial Chemistry
July 2010
ChemInform Abstract: Physical Properties of Polyethylene Glycol (PEG)-Based Resins for ...
ChemInform
May 2010
KHMDS Enhanced SmI<sub>2</sub>-Mediated Reformatsky Type α-Cyanation
Organic Letters
April 2010
Structural Influence on Radical Formation and Sensitizing Capacity of Alkylic Limonene ...
Chemical Research in Toxicology
February 2010
Synthesis of Chiral 1,4-Disubstituted-1,2,3-Triazole Derivatives from Amino Acids
Molecules
December 2009
Solid-Phase Peptide Synthesis in Water Using Microwave-Assisted Heating
Organic Letters
September 2009
Synthesis and Photophysical Characterisation of Fluorescent 8-(1<i>H</i>-1,2,3-Triazol-...
European Journal of Organic Chemistry
April 2009
Synthesis of 2-Alkyl-Substituted Chromone Derivatives Using Microwave Irradiation
The Journal of Organic Chemistry
March 2009
Synthesis of 3-(1,2,3-triazol-1-yl)- and 3-(1,2,3-triazol-4-yl)-substituted pyrazolo[3,...
Organic & Biomolecular Chemistry
January 2009
Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitorsvia [3+2]-cycloaddition chem...
New Journal of Chemistry
January 2009
Enhanced microwave-assisted method for on-bead disulfide bond formation: Synthesis of α...
Biopolymers
January 2009
Carbon- and Oxygen-Centered Radicals Are Equally Important Haptens of Allylic Hydropero...
Chemical Research in Toxicology
July 2008
Synthesis and photophysical properties of novel cyclonucleosides—substituent effects on...
Tetrahedron
July 2008
Microwave assisted synthesis of spiro-2,5-diketopiperazines
Tetrahedron
September 2007
A practical synthesis of 2′-aminoacylamino-2′-deoxyadenosines
Tetrahedron
July 2007
Synthesis of 3-Aminomethyl-2-aryl- 8-bromo-6-chlorochromones
Organic Letters
January 2007
Synthesis of Functionalized, Unsymmetrical 1,3,4,6-Tetrasubstituted 2,5-Diketopiperazines
The Journal of Organic Chemistry
December 2006
Microwave-Assisted Solid-Phase Synthesis of 2,5-Diketopiperazines: Solvent and Resin D...
Journal of Combinatorial Chemistry
October 2006
Synthesis of 2,3,6,8-Tetrasubstituted Chromone Scaffolds
The Journal of Organic Chemistry
August 2006
Efficient synthesis of 2,5-diketopiperazines using microwave assisted heating
Tetrahedron
July 2006
Microwave-assisted synthesis of the Schöllkopf chiral auxiliaries: (3S)- and (3R)-3,6-d...
Tetrahedron Letters
July 2006
A Scaffold Approach to 3,6,8-Trisubstituted Flavones
Synlett
April 2006
Discovering New Classes of Brugia malayi Asparaginyl-tRNA Synthetase Inhibitors and Rel...
Journal of Computer-Aided Molecular Design
March 2006
Synthesis of adenosine-based fluorosides containing a novel heterocyclic ring system
Tetrahedron Letters
September 2005
The Biotin Repressor: Modulation of Allostery by Corepressor Analogs
Journal of Molecular Biology
April 2004
Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthe...
Molecular Cell
April 2003
SPOCC-194, a New High Functional Group Density PEG-Based Resin for Solid-Phase Organic ...
Journal of Combinatorial Chemistry
August 2002
Palladium on Carbon Encapsulated in POEPOP<sub>1500</sub>: A Resin-Supported Catalyst ...
Organic Letters
December 2001
Solid-Phase Glycosylation of Peptide Templates and On-Bead MAS-NMR Analysis: Perspectiv...
Chemistry - A European Journal
August 2001
Diffusion of Reagents in Macrobeads
Journal of Combinatorial Chemistry
August 2001
A succession of substrate induced conformational changes ensures the amino acid specifi...
Journal of Molecular Biology
June 2001
ChemInform Abstract: Identification of Protease Inhibitors Using Biocompatible Resins a...
ChemInform
December 2000
Surfactant Mediated Cationic and Anionic Suspension Polymerization of PEG-Based Resins ...
Journal of Combinatorial Chemistry
November 2000
Crystallization and preliminary crystallographic analysis of<i>Thermus thermophilus</i>...
Acta Crystallographica Section D Biological Crystallography
May 2000
Physical Properties of Poly(ethylene glycol) (PEG)-Based Resins for Combinatorial Solid...
Journal of Combinatorial Chemistry
January 2000
Towards peptide isostere libraries: aqueous aldol reactions on hydrophilic solid supports
Journal of the Chemical Society Perkin Transactions 1
January 2000
HYDRA: A novel hydroxy and amine functionalised resin synthesised by reductive aminatio...
Journal of the Chemical Society Perkin Transactions 1
January 2000
Single-bead structure elucidation. Requirements for analysis of combinatorial solid-pha...
Journal of the Chemical Society Perkin Transactions 1
January 2000
SPOCC: A Resin for Solid-Phase Organic Chemistry and Enzymatic Reactions on Solid Phase
Journal of the American Chemical Society
May 1999
2′-O-(carbamoylmethyl)oligoribonucleotides
Tetrahedron
April 1999
Identification of Protease Inhibitors Using Biocompatible Resins and Library Synthesis
January 1999
2′-O-Propargyl oligoribonucleotides: Synthesis and hybridisation
Tetrahedron
May 1998
Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras
Tetrahedron
August 1997
A simple method for the synthesis of 2′-O-alkylguanosine derivatives
Bioorganic & Medicinal Chemistry Letters
February 1997
Protection of the guanine residue during synthesis of 2′-O-alkylguanosine derivatives
Journal of the Chemical Society Perkin Transactions 1
January 1997
Ether, Carbonate and Urethane Deoxynucleoside Derivatives as Prodrugs.
Acta Chemica Scandinavica
January 1996
Lithofibrin. A New Remarkably Stable Substance Found in Renal Stones.
Acta Chemica Scandinavica
January 1996
Synthesis of 2'-Allyl-2'-Deoxyribonucleosides by Radical Reactions.
Acta Chemica Scandinavica
January 1995
Design and Synthesis of Novel Chromone Based Peptidomimetics
SPOCC resins: Polar and chemically inert resins for organic synthesis and library enzym...
Investigation of enzyme activity and inhibition in the interior of novel solid supports