All Stories

  1. Synthesis and biological evaluation of novel C1 or C3 amino derivatives of A-ring 1,2,3-trisubstituted 19-nor-vitamin D3
  2. Manual and automated synthesis of modified oligonucleotides on core–shell solid supports
  3. The synthesis of solid supports carrying base labile linkers to generate 3′-phosphate oligonucleotides
  4. Synthesis of 2′-O-Methyl/2′-O-MOE-L-Nucleoside Derivatives and Their Applications: Preparation of G-Quadruplexes, Their Characterization, and Stability Studies
  5. Convergent Approaches and Biological Activity of C1 and/or C3 Mono or Diamino Derivatives of 1α,25‐Dihydroxy‐19‐nor‐vitamin D3. Key Enzymatic Desymmetrization of A‐Ring Synthon Precursor
  6. Sustainable Protocol for the Synthesis of 2′,3′-Dideoxynucleoside and 2′,3′-Didehydro-2′,3′-dideoxynucleoside Derivatives
  7. Oligonucleotides Containing 1-Aminomethyl or 1-Mercaptomethyl-2-deoxy-d-ribofuranoses: Synthesis, Purification, Characterization, and Conjugation with Fluorophores and Lipids
  8. Strategies for the Synthesis of 19-nor-Vitamin D Analogs
  9. Novel 1′-homo-N-2′-deoxy-α-nucleosides: synthesis, characterization and biological activity
  10. Enzymatic Desymmetrization of 19-nor -Vitamin D3 A-Ring Synthon Precursor: Synthesis, Structure Elucidation, and Biological Activity of 1α,25-Dihydroxy-3-epi -19-nor -vitamin D3 and 1β,25-Dihydroxy-19-nor -vitamin D3
  11. A-Ring-Modified 2-Hydroxyethylidene Previtamin D3 Analogues: Synthesis and Biological Evaluation
  12. The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biological properties of oligonucleotides
  13. Short and Efficient Chemoenzymatic Syntheses of non-Natural (−)-Muscarine and (+)-allo-Muscarine from Cyano-Sugar Precursors Catalyzed by ImmobilizedBurkholderia cepaciaLipase
  14. Preparation of ORMOSIL nanoparticles conjugated with vitamin D3analogues and their biological evaluation
  15. Process Development of Biocatalytic Regioselective 5′-O-Levulinylation of 2′-Deoxynucleosides
  16. Whole-cell biotransformation with recombinant cytochrome P450 for the selective oxidation of Grundmann’s ketone
  17. Biocatalysis: green processes for the preparation of protected nucleosides
  18. Synthesis of vitamin D3 analogues with A-ring modifications to directly measure vitamin D levels in biological samples
  19. Biocatalytic Methodologies for Selective Modified Nucleosides
  20. Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′,3′-dideoxy-2′,2′-difluoro-4′-azanucleosides
  21. CAL-B-Catalyzed Acylation of Nucleosides and Role of the Sugar Conformation: An Improved Understanding of the Enzyme-Substrate Recognition
  22. Design and Divergent Synthesis of Aza Nucleosides from a Chiral Imino Sugar
  23. An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotide synthesis
  24. Chemoenzymatic Syntheses and Anti-HIV-1 Activity of Glucose−Nucleoside Conjugates as Prodrugs
  25. Enzymatic Parallel Kinetic Resolution of Mixtures ofd/l2′-Deoxy and Ribonucleosides: An Approach for the Isolation of β-l-Nucleosides†
  26. Synthesis of81Br-Labeled Polybrominated Diphenyl Ethers and Their Characterization Using GC(EI)MS and GC(ICP)MS
  27. Chemoenzymatic Synthesis of 3′-O-Acetal-Protected 2′-Deoxynucleosides as Building Blocks for Nucleic Acid Chemistry
  28. Synthesis, Conformational Analysis, and Biological Evaluation of 19-nor-Vitamin D3Analogues with A-Ring Modifications
  29. Improved Synthesis and Isolation of 2′-O-Methyladenosine: Effective and Scalable Enzymatic Separation of 2′/3′-O-Methyladenosine Regioisomers
  30. Synthesis and anti-HIV activity of conformationally restricted bicyclic hexahydroisobenzofuran nucleoside analogs
  31. Synthesis and biological activity of previtamin D3 analogues with A-ring modifications
  32. Preparation of Nucleoside-Carbohydrate Phosphodiester Prodrug Analogues by Chemoenzymatic Procedure
  33. Novel and Efficient Chemoenzymatic Synthesis ofD-Glucose 6-Phosphate and Molecular Modeling Studies on the Selective Biocatalysis
  34. Synthesis and biological evaluation of new 6-s-cis locked 1,2,25-trihydroxyprevitamin D3 analogues
  35. Enzymatic resolution of hindered cyanohydrins, key precursors of muscarinic receptor antagonists
  36. New Concept for the Separation of an Anomeric Mixture of α/β-d-Nucleosides through Regioselective Enzymatic Acylation or Hydrolysis Processes
  37. Novel A-ring homodimeric C-3-carbamate analogues of 1α,25-dihydroxyvitamin D3: Synthesis and preliminary biological evaluation
  38. Novel and Efficient Syntheses of (−)-Methyl 4-epi-Shikimate and 4,5-Epoxy-Quinic and -Shikimic Acid Derivatives as Key Precursors to Prepare New Analogues
  39. Influence of intramolecular hydrogen bonds in the enzyme-catalyzed regioselective acylation of quinic and shikimic acid derivatives
  40. Novel Chemoenzymatic Protocol for the Synthesis of 3‘-O-Dimethoxytrityl-2‘-deoxynucleoside Derivatives as Building Blocks for Oligonucleotide Synthesis
  41. Remote Interactions Explain the Unusual Regioselectivity of Lipase from Pseudomonas cepacia toward the Secondary Hydroxyl of 2′-Deoxynucleosides
  42. Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1α,25-dihydroxyvitamin D3 analogues
  43. Novel and efficient regioselective enzymatic approach to 3′-, 5′- and 3′,5′-di-O-crotonyl 2′-deoxynucleoside derivatives
  44. An Inverse Substrate Orientation for the Regioselective Acylation of 3′,5′-Diaminonucleosides Catalyzed by Candida antarctica lipase B?
  45. Chemoenzymatic Syntheses of Homo‐ and Heterodimers of AZT and d4T, and Evaluation of Their Anti‐HIV Activity
  46. Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1α,25-dihydroxyvitamin D3
  47. Regioselective Enzymatic Acylation of β-l-2‘-Deoxynucleosides:  Application in Resolution of β-d/l-2‘-Deoxynucleosides
  48. Regioselective enzymatic syntheses of C-3 and C-5 carbonate A-ring stereoisomeric precursors of vitamin D
  49. First Regioselective Enzymatic Alkoxycarbonylation of Primary Amines. Synthesis of Novel 5‘- and 3‘-Carbamates of Pyrimidine 3‘,5‘-Diaminonucleoside Derivatives Including BVDU Analogues
  50. A mild, efficient and regioselective enzymatic procedure for 5′-O-benzoylation of 2′-deoxynucleosides
  51. Novel enzymatic synthesis of levulinyl protected nucleosides useful for solution phase synthesis of oligonucleotides
  52. Synthesis, Protonation Behavior, Conformational Analysis, and Regioselective Enzymatic Acylation of the Novel Diamino Analogue of (E)-5-(2-Bromovinyl)-2′-deoxyuridine (BVDU)
  53. Synthesis and Antiviral Activity Assay of Novel (E)-3′,5′-Diamino-5-(2-bromovinyl)-2′,3′,5′-trideoxyuridine
  54. Direct Regioselective Enzymatic Acylation of Nucleosides: Building-Blocks for the Solution Phase Synthesis of Oligonucleotides
  55. Novel and efficient syntheses of 3′,5′-diamino derivatives of 2′,3′,5′-trideoxycytidine and 2′,3′,5′-trideoxyadenosine. Protonation behavior of 3′,5′-diaminonucleosides
  56. Novel Enzymatic Synthesis of 4-O-Cinnamoyl Quinic and Shikimic Acid Derivatives
  57. Efficient Synthesis of Novel 1α-Amino and 3β-Amino Analogues of 1α,25-Dihydroxyvitamin D3
  58. Clean-chemistry synthesis of biodegradable tertiary α-substituted carboxylic acids from the corresponding esters through enzymatic processes
  59. Regioselective Enzymatic Acylation of Methyl Shikimate. Influence of Acyl Chain Length and Solvent Polarity on Enzyme Specificity
  60. Building Blocks for the Solution Phase Synthesis of Oligonucleotides:  Regioselective Hydrolysis of 3‘,5‘-Di-O-levulinylnucleosides Using an Enzymatic Approach
  61. DIFFICULTIES IN THE DEPROTECTION OF 1,2-KETALS IN NUCLEOSIDES CONTAINING ALKYLIDENCARBAZOYL GROUPS
  62. Novel chiral precursors of 6-s-cis locked 1α,25-dihydroxyvitamin D3 analogues through selective enzymatic acylation
  63. Synthesis of Monoacyl A-Ring Precursors of 1α,25-Dihydroxyvitamin D3 through Selective Enzymatic Hydrolysis
  64. First Regioselective Enzymatic Acylation of Amino Groups Applied to Pyrimidine 3‘,5‘-Diaminonucleoside Derivatives. Improved Synthesis of Pyrimidine 3‘,5‘-Diamino-2‘,3‘,5‘-trideoxynucleosides
  65. CAL-B-Catalyzed Alkoxycarbonylation of A-Ring Stereoisomeric Synthons of 1α,25-Dihydroxyvitamin D3and 1α,25-Dihydroxy-19-nor-previtamin D3:  A Comparative Study. First Regioselective Chemoenzymatic Synthesis of 19-nor-A-Ring Carbonates
  66. SYNTHESIS OF NEW HOMO AND HETERODINUCLEOSIDES CONTAINING THE 2′,3′-DIDEOXYNUCLEOSIDES AZT AND D4T
  67. SYNTHESIS OF IMIDAZOYLTHIOCARBONYL INTERMEDIATES FOR THE RADICAL DEOXYGENATION OF HINDERED SECONDARY ALCOHOLS
  68. Biocatalytic Selective Modifications of Conventional Nucleosides, Carbocyclic Nucleosides, andC-Nucleosides
  69. Efficient synthesis of (−)-methyl 3-epi-shikimate and methyl 3-epi-quinate by one-pot selective protection of trans-1,2-diols
  70. 6-s-cisLocked Analogues of the Steroid Hormone 1α,25-Dihydroxyvitamin D3. Synthesis of Novel A-Ring Stereoisomeric 1,25-Dihydroxy-3-epi-19-nor-previtamin D3Derivatives
  71. Chemoenzymatic Transformationsin Nucleoside Chemistry
  72. Biocatalytic Synthesis of Steroids
  73. Chemoenzymatic Transformations in Nucleoside Chemistry
  74. Synthesis of two 6-s-cis locked stereoisomeric analogues of the steroid hormone 1α,25-dihydroxyvitamin D3: 1α,25-dihydroxy-19-nor-previtamin D3 and 1β,25-dihydroxy-19-nor-previtamin D3
  75. Enzymatic Regioselective Transformations in Natural Products
  76. 1α,25-Dihydroxyvitamin D3 A-Ring Precursors:  Studies on Regioselective Enzymatic Alkoxycarbonylation Reactions of Their Stereoisomers. Chemoenzymatic Synthesis of A-Ring Synthon Carbamate Derivatives, Including Carbazates and Polyamino Carb...
  77. Synthesis of novel carbazoyl linked pyrimidine-pyrimidine and pyrimidine-purine dinucleotide analogues
  78. Chemoenzymatic Synthesis of Novel 3‘- and 5‘-Carbazoyl Nucleoside Derivatives. Regioselective Preparation of 3‘- and 5‘-Alkylidencarbazoyl Nucleosides
  79. New and efficient enantiospecific synthesis of (−)-Methyl 5-epi-shikimate and methyl 5-epi-quinate from (−)-quinic acid
  80. Selective Alkoxycarbonylation of A-Ring Precursors of Vitamin D Using Enzymes in Organic Solvents. Chemoenzymatic Synthesis of 1α,25-Dihydroxyvitamin D3C-5 A-Ring Carbamate Derivatives1
  81. Synthesis of pentasubstituted pyridines. Cycloadditions of N -vinylic heterocumulenes with 1-( N , N -diethylamine)prop-1-yne
  82. Synthesis of Pentasubstituted Pyridines. IV—Structural Characterization of the Addition Products of 1-(N,N-Diethylamine)prop-1-yne toN-Vinylcarbodiimides and -ketenimines
  83. Selective Acylation of A-Ring Precursors of Vitamin D Using Enzymes in Organic Solvents
  84. Synthesis of pentasubstituted pyridines. II—NMR study of the addition products of 1-(N,N-diethylamine)prop-1-yne to methyl 2-isothiocyanato-3-phenylpropenoate
  85. A new domino synthesis of polyfunctionalized pentasubstituted pyridines
  86. Reactivity and selectivity of N-vinylic λ5-phosphazenes towards electrophiles. Synthesis of 2-aza-1,3-dienes
  87. A simple and efficient “one-pot” synthesis of 2-aza-1,3-butadienes from N-vinylic λ5phosphazenes
  88. Reaction of α-metallated N-acyl-λ5-phosphazenes with aryl cyanides
  89. An efficient and mild conditions synthesis of 2-aza-1,3-dienes fromphospha-λ5-azenes.
  90. Enzymatic Selectivity in Synthetic Methods