Prof. Dr. Miguel Ferrero

Strategies for the Synthesis of 19-nor-Vitamin D Analogs

• Pharmaceuticals
• July 2020

Novel 1′-homo-N-2′-deoxy-α-nucleosides: synthesis, characterization and biological acti...

• RSC Advances
• January 2020

Enzymatic Desymmetrization of 19-nor -Vitamin D3 A-Ring Synthon Precursor: Synthesis, ...

• Advanced Synthesis & Catalysis
• June 2018

A-Ring-Modified 2-Hydroxyethylidene Previtamin D3 Analogues: Synthesis and Biological ...

• European Journal of Organic Chemistry
• January 2017

The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biolo...

• RSC Advances
• January 2017

Short and Efficient Chemoenzymatic Syntheses of non-Natural (−)-Muscarine and (+)-allo-...

• Advanced Synthesis & Catalysis
• December 2016

Preparation of ORMOSIL nanoparticles conjugated with vitamin D3analogues and their biol...

• RSC Advances
• January 2016

Process Development of Biocatalytic Regioselective 5′-O-Levulinylation of 2′-Deoxynucle...

• Organic Process Research & Development
• June 2015

Whole-cell biotransformation with recombinant cytochrome P450 for the selective oxidati...

• Bioorganic & Medicinal Chemistry
• October 2014

Biocatalysis: green processes for the preparation of protected nucleosides

• January 2014

Synthesis of vitamin D3 analogues with A-ring modifications to directly measure vitamin...

• Bioorganic & Medicinal Chemistry
• December 2013

Biocatalytic Methodologies for Selective Modified Nucleosides

• February 2013

Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′,3′-dideoxy-2′,2′-...

• Bioorganic & Medicinal Chemistry
• December 2012

CAL-B-Catalyzed Acylation of Nucleosides and Role of the Sugar Conformation: An Improve...

• European Journal of Organic Chemistry
• August 2012

Design and Divergent Synthesis of Aza Nucleosides from a Chiral Imino Sugar

• The Journal of Organic Chemistry
• May 2012

An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotid...

• Organic & Biomolecular Chemistry
• January 2011

Chemoenzymatic Syntheses and Anti-HIV-1 Activity of Glucose−Nucleoside Conjugates as Pr...

• Bioconjugate Chemistry
• December 2010

Enzymatic Parallel Kinetic Resolution of Mixtures ofd/l2′-Deoxy and Ribonucleosides: An...

• The Journal of Organic Chemistry
• October 2010

Synthesis of81Br-Labeled Polybrominated Diphenyl Ethers and Their Characterization Usin...

• Analytical Chemistry
• April 2010

Chemoenzymatic Synthesis of 3′-O-Acetal-Protected 2′-Deoxynucleosides as Building Block...

• European Journal of Organic Chemistry
• March 2010

Synthesis, Conformational Analysis, and Biological Evaluation of 19-nor-Vitamin D3Analo...

• Journal of Medicinal Chemistry
• October 2009

Improved Synthesis and Isolation of 2′-O-Methyladenosine: Effective and Scalable Enzyma...

• European Journal of Organic Chemistry
• July 2009

Synthesis and anti-HIV activity of conformationally restricted bicyclic hexahydroisoben...

• Organic & Biomolecular Chemistry
• January 2009

Synthesis and biological activity of previtamin D3 analogues with A-ring modifications

• Bioorganic & Medicinal Chemistry
• December 2008

Novel and Efficient Chemoenzymatic Synthesis ofD-Glucose 6-Phosphate and Molecular Mode...

• European Journal of Organic Chemistry
• June 2007

Synthesis and biological evaluation of new 6-s-cis locked 1,2,25-trihydroxyprevitamin D...

• Bioorganic & Medicinal Chemistry
• June 2007

Enzymatic resolution of hindered cyanohydrins, key precursors of muscarinic receptor an...

• Tetrahedron Asymmetry
• May 2007

New Concept for the Separation of an Anomeric Mixture of α/β-d-Nucleosides through Regi...

• The Journal of Organic Chemistry
• December 2006

Novel A-ring homodimeric C-3-carbamate analogues of 1α,25-dihydroxyvitamin D3: Synthesi...

• Bioorganic & Medicinal Chemistry
• November 2006

Novel and Efficient Syntheses of (−)-Methyl 4-epi-Shikimate and 4,5-Epoxy-Quinic and -S...

• The Journal of Organic Chemistry
• July 2006

Influence of intramolecular hydrogen bonds in the enzyme-catalyzed regioselective acyla...

• Tetrahedron
• June 2006

Novel Chemoenzymatic Protocol for the Synthesis of 3‘-O-Dimethoxytrityl-2‘-deoxynucleos...

• Organic Process Research & Development
• May 2006

Remote Interactions Explain the Unusual Regioselectivity of Lipase from Pseudomonas cep...

• ChemBioChem
• February 2006

Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1α,25-dihydrox...

• Bioorganic & Medicinal Chemistry
• February 2006

Novel and efficient regioselective enzymatic approach to 3′-, 5′- and 3′,5′-di-O-croton...

• Tetrahedron Letters
• August 2005

An Inverse Substrate Orientation for the Regioselective Acylation of 3′,5′-Diaminonucle...

• ChemBioChem
• June 2005

Chemoenzymatic Syntheses of Homo‐ and Heterodimers of AZT and d4T, and Evaluation of Th...

• Nucleosides Nucleotides & Nucleic Acids
• December 2004

Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1α,25-...

• Bioorganic & Medicinal Chemistry
• October 2004

Regioselective Enzymatic Acylation of β-l-2‘-Deoxynucleosides:  Application in Resoluti...

• Organic Letters
• October 2004

Regioselective enzymatic syntheses of C-3 and C-5 carbonate A-ring stereoisomeric precu...

• Tetrahedron Asymmetry
• September 2004

First Regioselective Enzymatic Alkoxycarbonylation of Primary Amines. Synthesis of Nove...

• The Journal of Organic Chemistry
• March 2004

A mild, efficient and regioselective enzymatic procedure for 5′-O-benzoylation of 2′-de...

• Tetrahedron Letters
• February 2004

Novel enzymatic synthesis of levulinyl protected nucleosides useful for solution phase ...

• Tetrahedron Asymmetry
• November 2003

Synthesis, Protonation Behavior, Conformational Analysis, and Regioselective Enzymatic ...

• Nucleosides Nucleotides & Nucleic Acids
• October 2003

Synthesis and Antiviral Activity Assay of Novel (E)-3′,5′-Diamino-5-(2-bromovinyl)-2′,3...

• Nucleosides Nucleotides & Nucleic Acids
• October 2003

Direct Regioselective Enzymatic Acylation of Nucleosides: Building-Blocks for the Solut...

• Nucleosides Nucleotides & Nucleic Acids
• October 2003

Novel and efficient syntheses of 3′,5′-diamino derivatives of 2′,3′,5′-trideoxycytidine...

• Tetrahedron
• July 2003

Novel Enzymatic Synthesis of 4-O-Cinnamoyl Quinic and Shikimic Acid Derivatives

• The Journal of Organic Chemistry
• July 2003

Efficient Synthesis of Novel 1α-Amino and 3β-Amino Analogues of 1α,25-Dihydroxyvitamin D3

• The Journal of Organic Chemistry
• February 2003

Clean-chemistry synthesis of biodegradable tertiary α-substituted carboxylic acids from...

• Journal of Molecular Catalysis B Enzymatic
• December 2002

Regioselective Enzymatic Acylation of Methyl Shikimate. Influence of Acyl Chain Length ...

• The Journal of Organic Chemistry
• July 2002

Building Blocks for the Solution Phase Synthesis of Oligonucleotides:  Regioselective H...

• The Journal of Organic Chemistry
• June 2002

DIFFICULTIES IN THE DEPROTECTION OF 1,2-KETALS IN NUCLEOSIDES CONTAINING ALKYLIDENCARBA...

• Nucleosides Nucleotides & Nucleic Acids
• April 2002

Novel chiral precursors of 6-s-cis locked 1α,25-dihydroxyvitamin D3 analogues through s...

• Tetrahedron Asymmetry
• April 2002

Synthesis of Monoacyl A-Ring Precursors of 1α,25-Dihydroxyvitamin D3through Selective E...

• The Journal of Organic Chemistry
• February 2002

First Regioselective Enzymatic Acylation of Amino Groups Applied to Pyrimidine 3‘,5‘-Di...

• The Journal of Organic Chemistry
• June 2001

CAL-B-Catalyzed Alkoxycarbonylation of A-Ring Stereoisomeric Synthons of 1α,25-Dihydrox...

• The Journal of Organic Chemistry
• June 2001

SYNTHESIS OF NEW HOMO AND HETERODINUCLEOSIDES CONTAINING THE 2′,3′-DIDEOXYNUCLEOSIDES A...

• Nucleosides Nucleotides & Nucleic Acids
• March 2001

SYNTHESIS OF IMIDAZOYLTHIOCARBONYL INTERMEDIATES FOR THE RADICAL DEOXYGENATION OF HINDE...

• Synthetic Communications
• January 2001

Biocatalytic Selective Modifications of Conventional Nucleosides, Carbocyclic Nucleosid...

• Chemical Reviews
• December 2000

6-s-cisLocked Analogues of the Steroid Hormone 1α,25-Dihydroxyvitamin D3. Synthesis of ...

• The Journal of Organic Chemistry
• September 2000

Biocatalytic Synthesis of Steroids

• January 2000

Chemoenzymatic Transformations in Nucleoside Chemistry

• January 2000

Synthesis of two 6-s-cis locked stereoisomeric analogues of the steroid hormone 1α,25-d...

• Tetrahedron Letters
• January 2000

1α,25-Dihydroxyvitamin D3A-Ring Precursors:  Studies on Regioselective Enzymatic Alkoxy...

• The Journal of Organic Chemistry
• October 1999

Synthesis of novel carbazoyl linked pyrimidine-pyrimidine and pyrimidine-purine dinucle...

• Tetrahedron Letters
• February 1999

Chemoenzymatic Synthesis of Novel 3‘- and 5‘-Carbazoyl Nucleoside Derivatives. Regiosel...

• The Journal of Organic Chemistry
• November 1998

New and efficient enantiospecific synthesis of (−)-Methyl 5-epi-shikimate and methyl 5-...

• Tetrahedron Letters
• July 1997

Synthesis of pentasubstituted pyridines. Cycloadditions of N -vinylic heterocumulenes ...

• Tetrahedron
• March 1997

Synthesis of Pentasubstituted Pyridines. IV—Structural Characterization of the Addition...

• Magnetic Resonance in Chemistry
• May 1996

Selective Acylation of A-Ring Precursors of Vitamin D Using Enzymes in Organic Solvents

• The Journal of Organic Chemistry
• September 1995

Synthesis of pentasubstituted pyridines. II—NMR study of the addition products of 1-(N,...

• Magnetic Resonance in Chemistry
• November 1994

A new domino synthesis of polyfunctionalized pentasubstituted pyridines

• Journal of the Chemical Society Chemical Communications
• January 1994

Reactivity and selectivity of N-vinylic λ5-phosphazenes towards electrophiles. Synthesi...

• Journal of the Chemical Society Perkin Transactions 1
• January 1990

A simple and efficient “one-pot” synthesis of 2-aza-1,3-butadienes from N-vinylic λ5pho...

• Tetrahedron Letters
• January 1990

Reaction of α-metallated N-acyl-λ5-phosphazenes with aryl cyanides

• Journal of the Chemical Society Perkin Transactions 1
• January 1989

An efficient and mild conditions synthesis of 2-aza-1,3-dienes fromphospha-λ5-azenes.

• Tetrahedron Letters
• January 1988

Enzymatic Selectivity in Synthetic Methods