Prof. Dr. Miguel Ferrero
Universidad de Oviedo
Professor, Chemistry
Spain
My co-authors include
Ramon Eritja
Dr Ivan Lavandera
Find me at
My Publications
Strategies for the Synthesis of 19-nor-Vitamin D Analogs
Pharmaceuticals
July 2020
Novel 1′-homo-<i>N</i>-2′-deoxy-α-nucleosides: synthesis, characterization and biologic...
RSC Advances
January 2020
Enzymatic Desymmetrization of 19-nor -Vitamin D3 A-Ring Synthon Precursor: Synthesis, ...
Advanced Synthesis & Catalysis
June 2018
A-Ring-Modified 2-Hydroxyethylidene Previtamin D3 Analogues: Synthesis and Biological ...
European Journal of Organic Chemistry
January 2017
The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biolo...
RSC Advances
January 2017
Short and Efficient Chemoenzymatic Syntheses of non-Natural (−)-Muscarine and (+)-allo-...
Advanced Synthesis & Catalysis
December 2016
Preparation of ORMOSIL nanoparticles conjugated with vitamin D<sub>3</sub>analogues and...
RSC Advances
January 2016
Process Development of Biocatalytic Regioselective 5′-O-Levulinylation of 2′-Deoxynucle...
Organic Process Research & Development
June 2015
Whole-cell biotransformation with recombinant cytochrome P450 for the selective oxidati...
Bioorganic & Medicinal Chemistry
October 2014
Biocatalysis: green processes for the preparation of protected nucleosides
January 2014
Synthesis of vitamin D3 analogues with A-ring modifications to directly measure vitamin...
Bioorganic & Medicinal Chemistry
December 2013
Biocatalytic Methodologies for Selective Modified Nucleosides
February 2013
Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′,3′-dideoxy-2′,2′-...
Bioorganic & Medicinal Chemistry
December 2012
CAL-B-Catalyzed Acylation of Nucleosides and Role of the Sugar Conformation: An Improve...
European Journal of Organic Chemistry
August 2012
Design and Divergent Synthesis of Aza Nucleosides from a Chiral Imino Sugar
The Journal of Organic Chemistry
May 2012
An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotid...
Organic & Biomolecular Chemistry
January 2011
Chemoenzymatic Syntheses and Anti-HIV-1 Activity of Glucose−Nucleoside Conjugates as Pr...
Bioconjugate Chemistry
December 2010
Enzymatic Parallel Kinetic Resolution of Mixtures ofd/l2′-Deoxy and Ribonucleosides: An...
The Journal of Organic Chemistry
October 2010
Synthesis of81Br-Labeled Polybrominated Diphenyl Ethers and Their Characterization Usin...
Analytical Chemistry
April 2010
Chemoenzymatic Synthesis of 3′-O-Acetal-Protected 2′-Deoxynucleosides as Building Block...
European Journal of Organic Chemistry
March 2010
Synthesis, Conformational Analysis, and Biological Evaluation of 19-nor-Vitamin D3Analo...
Journal of Medicinal Chemistry
October 2009
Improved Synthesis and Isolation of 2′-O-Methyladenosine: Effective and Scalable Enzyma...
European Journal of Organic Chemistry
July 2009
Synthesis and anti-HIV activity of conformationally restricted bicyclic hexahydroisoben...
Organic & Biomolecular Chemistry
January 2009
Synthesis and biological activity of previtamin D3 analogues with A-ring modifications
Bioorganic & Medicinal Chemistry
December 2008
Novel and Efficient Chemoenzymatic Synthesis ofD-Glucose 6-Phosphate and Molecular Mode...
European Journal of Organic Chemistry
June 2007
Synthesis and biological evaluation of new 6-s-cis locked 1,2,25-trihydroxyprevitamin D...
Bioorganic & Medicinal Chemistry
June 2007
Enzymatic resolution of hindered cyanohydrins, key precursors of muscarinic receptor an...
Tetrahedron Asymmetry
May 2007
New Concept for the Separation of an Anomeric Mixture of α/β-d-Nucleosides through Regi...
The Journal of Organic Chemistry
December 2006
Novel A-ring homodimeric C-3-carbamate analogues of 1α,25-dihydroxyvitamin D3: Synthesi...
Bioorganic & Medicinal Chemistry
November 2006
Novel and Efficient Syntheses of (−)-Methyl 4-epi-Shikimate and 4,5-Epoxy-Quinic and -S...
The Journal of Organic Chemistry
July 2006
Influence of intramolecular hydrogen bonds in the enzyme-catalyzed regioselective acyla...
Tetrahedron
June 2006
Novel Chemoenzymatic Protocol for the Synthesis of 3‘-O-Dimethoxytrityl-2‘-deoxynucleos...
Organic Process Research & Development
May 2006
Remote Interactions Explain the Unusual Regioselectivity of Lipase from Pseudomonas cep...
ChemBioChem
February 2006
Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1α,25-dihydrox...
Bioorganic & Medicinal Chemistry
February 2006
Novel and efficient regioselective enzymatic approach to 3′-, 5′- and 3′,5′-di-O-croton...
Tetrahedron Letters
August 2005
An Inverse Substrate Orientation for the Regioselective Acylation of 3′,5′-Diaminonucle...
ChemBioChem
June 2005
Chemoenzymatic Syntheses of Homo‐ and Heterodimers of AZT and d4T, and Evaluation of Th...
Nucleosides Nucleotides & Nucleic Acids
December 2004
Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1α,25-...
Bioorganic & Medicinal Chemistry
October 2004
Regioselective Enzymatic Acylation of β-l-2‘-Deoxynucleosides: Application in Resoluti...
Organic Letters
October 2004
Regioselective enzymatic syntheses of C-3 and C-5 carbonate A-ring stereoisomeric precu...
Tetrahedron Asymmetry
September 2004
First Regioselective Enzymatic Alkoxycarbonylation of Primary Amines. Synthesis of Nove...
The Journal of Organic Chemistry
March 2004
A mild, efficient and regioselective enzymatic procedure for 5′-O-benzoylation of 2′-de...
Tetrahedron Letters
February 2004
Novel enzymatic synthesis of levulinyl protected nucleosides useful for solution phase ...
Tetrahedron Asymmetry
November 2003
Synthesis, Protonation Behavior, Conformational Analysis, and Regioselective Enzymatic ...
Nucleosides Nucleotides & Nucleic Acids
October 2003
Synthesis and Antiviral Activity Assay of Novel (E)-3′,5′-Diamino-5-(2-bromovinyl)-2′,3...
Nucleosides Nucleotides & Nucleic Acids
October 2003
Direct Regioselective Enzymatic Acylation of Nucleosides: Building-Blocks for the Solut...
Nucleosides Nucleotides & Nucleic Acids
October 2003
Novel and efficient syntheses of 3′,5′-diamino derivatives of 2′,3′,5′-trideoxycytidine...
Tetrahedron
July 2003
Novel Enzymatic Synthesis of 4-O-Cinnamoyl Quinic and Shikimic Acid Derivatives
The Journal of Organic Chemistry
July 2003
Efficient Synthesis of Novel 1α-Amino and 3β-Amino Analogues of 1α,25-Dihydroxyvitamin D3
The Journal of Organic Chemistry
February 2003
Clean-chemistry synthesis of biodegradable tertiary α-substituted carboxylic acids from...
Journal of Molecular Catalysis B Enzymatic
December 2002
Regioselective Enzymatic Acylation of Methyl Shikimate. Influence of Acyl Chain Length ...
The Journal of Organic Chemistry
July 2002
Building Blocks for the Solution Phase Synthesis of Oligonucleotides: Regioselective H...
The Journal of Organic Chemistry
June 2002
DIFFICULTIES IN THE DEPROTECTION OF 1,2-KETALS IN NUCLEOSIDES CONTAINING ALKYLIDENCARBA...
Nucleosides Nucleotides & Nucleic Acids
April 2002
Novel chiral precursors of 6-s-cis locked 1α,25-dihydroxyvitamin D3 analogues through s...
Tetrahedron Asymmetry
April 2002
Synthesis of Monoacyl A-Ring Precursors of 1α,25-Dihydroxyvitamin D<sub>3</sub> through...
The Journal of Organic Chemistry
January 2002
First Regioselective Enzymatic Acylation of Amino Groups Applied to Pyrimidine 3‘,5‘-Di...
The Journal of Organic Chemistry
June 2001
CAL-B-Catalyzed Alkoxycarbonylation of A-Ring Stereoisomeric Synthons of 1α,25-Dihydrox...
The Journal of Organic Chemistry
June 2001
SYNTHESIS OF NEW HOMO AND HETERODINUCLEOSIDES CONTAINING THE 2′,3′-DIDEOXYNUCLEOSIDES A...
Nucleosides Nucleotides & Nucleic Acids
March 2001
SYNTHESIS OF IMIDAZOYLTHIOCARBONYL INTERMEDIATES FOR THE RADICAL DEOXYGENATION OF HINDE...
Synthetic Communications
January 2001
Biocatalytic Selective Modifications of Conventional Nucleosides, Carbocyclic Nucleosid...
Chemical Reviews
December 2000
6-s-cisLocked Analogues of the Steroid Hormone 1α,25-Dihydroxyvitamin D3. Synthesis of ...
The Journal of Organic Chemistry
September 2000
Biocatalytic Synthesis of Steroids
January 2000
Chemoenzymatic Transformations in Nucleoside Chemistry
January 2000
Synthesis of two 6-s-cis locked stereoisomeric analogues of the steroid hormone 1α,25-d...
Tetrahedron Letters
January 2000
1α,25-Dihydroxyvitamin D<sub>3</sub> A-Ring Precursors: Studies on Regioselective Enzy...
The Journal of Organic Chemistry
September 1999
Synthesis of novel carbazoyl linked pyrimidine-pyrimidine and pyrimidine-purine dinucle...
Tetrahedron Letters
February 1999
Chemoenzymatic Synthesis of Novel 3‘- and 5‘-Carbazoyl Nucleoside Derivatives. Regiosel...
The Journal of Organic Chemistry
November 1998
New and efficient enantiospecific synthesis of (−)-Methyl 5-epi-shikimate and methyl 5-...
Tetrahedron Letters
July 1997
Synthesis of pentasubstituted pyridines. Cycloadditions of N -vinylic heterocumulenes ...
Tetrahedron
March 1997
Synthesis of Pentasubstituted Pyridines. IV—Structural Characterization of the Addition...
Magnetic Resonance in Chemistry
May 1996
Selective Acylation of A-Ring Precursors of Vitamin D Using Enzymes in Organic Solvents
The Journal of Organic Chemistry
September 1995
Synthesis of pentasubstituted pyridines. II—NMR study of the addition products of 1-(N,...
Magnetic Resonance in Chemistry
November 1994
A new domino synthesis of polyfunctionalized pentasubstituted pyridines
Journal of the Chemical Society Chemical Communications
January 1994
Reactivity and selectivity of N-vinylic λ<sup>5</sup>-phosphazenes towards electrophile...
Journal of the Chemical Society Perkin Transactions 1
January 1990
A simple and efficient “one-pot” synthesis of 2-aza-1,3-butadienes from N-vinylic λ5pho...
Tetrahedron Letters
January 1990
Reaction of α-metallated N-acyl-λ5-phosphazenes with aryl cyanides
Journal of the Chemical Society Perkin Transactions 1
January 1989
An efficient and mild conditions synthesis of 2-aza-1,3-dienes fromphospha-λ5-azenes.
Tetrahedron Letters
January 1988
Enzymatic Selectivity in Synthetic Methods