Antiviral activity of lipid-DNA molecules
What is it about?
Drugs composed of a DNA fragment and a lipid are able to block the entry of hepatitis C virus in liver cells. The DNA fragment has a special sequence that increases the efficacy of the inhibition.
Why is it important?
Hepatitis C virus is responsable of a life-threatening disease. The novel drug inhibit the recognition event between the capside viral protein and the membrane receptors of the hepatic cells. This mechanism can be used for the design of novel antiviral drugs.
The following have contributed to this page: Ramon Eritja