Successful evaluation of a nanodrug against metastasis
What is it about?
Cancer metastasis is one of the most deathly consequences of cancer. We describe the preparation and evaluation in a mouse model of a protein nanoparticle carrying several units of an anticancer drug (floxuridine) that is given intravenously. The nanodrug is able to circulate in the blood and find the metastasic cells by binding to an overexpressed receptor (CXCR4) present in Cancer Stem Cells. The efficient removal of the metastasic cells is proven in several mouse models.
Why is it important?
The manuscript defines a potential therapeutic solution for the treatment of metastasis from colon cancer.
The following have contributed to this page: Ramon Eritja