Dr James E Crowe
Vanderbilt University Medical Center
Professor, Medicine And Medical Sciences
United States
My co-authors include
Dr Randy A Albrecht
Dr Robert H Carnahan
Terence Dermody
Find me at
My Publications
Peptide arrays incubated with three collections of human sera from patients infected wi...
F1000Research
February 2020
Peptide arrays of three collections of human sera from patients infected with mosquito-...
F1000Research
February 2020
Multi-state design of flexible proteins predicts sequences optimal for conformational c...
PLoS Computational Biology
February 2020
Broad dengue neutralization in mosquitoes expressing an engineered antibody
PLoS Pathogens
January 2020
Human-likeness of antibody biologics determined by back-translation and comparison with...
mAbs
January 2020
Immune repertoire fingerprinting by principal component analysis reveals shared feature...
BMC Bioinformatics
December 2019
Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral E...
Cell Host & Microbe
December 2019
Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminid...
Cell Host & Microbe
December 2019
Mechanism of differential Zika and dengue virus neutralization by a public antibody lin...
The Journal of Experimental Medicine
November 2019
Peptide arrays of three collections of human sera from patients infected with mosquito-...
F1000Research
November 2019
Human VH1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus Isd...
mBio
October 2019
Harmonization of Zika neutralization assays by using the WHO International Standard for...
npj Vaccines
October 2019
Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ ...
ACS Nano
October 2019
Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunit...
Infection and Immunity
September 2019
Multi-State Design of Flexible Proteins Predicts Sequences Optimal for Conformational C...
August 2019
Plasma deconvolution identifies broadly neutralizing antibodies associated with hepatit...
Journal of Clinical Investigation
August 2019
Characterization of recombinant yellow fever-dengue vaccine viruses with human monoclon...
Vaccine
July 2019
New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transpl...
Biology of Blood and Marrow Transplantation
June 2019
A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody pr...
Science Immunology
May 2019
Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Vir...
Journal of Virology
May 2019
A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface
Cell
May 2019
Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebol...
Nature Communications
April 2019
Antibody Determinants of Influenza Immunity
The Journal of Infectious Diseases
April 2019
Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains
Frontiers in Immunology
March 2019
High frequency of shared clonotypes in human B cell receptor repertoires
Nature
February 2019
Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection
Journal of Virology
February 2019
Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin ...
PLoS Biology
February 2019
Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondw...
Cell Reports
February 2019
Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by...
Structure
February 2019
Multistate design of influenza antibodies improves affinity and breadth against seasona...
Proceedings of the National Academy of Sciences
January 2019
Structural basis of a potent human monoclonal antibody against Zika virus targeting a q...
Proceedings of the National Academy of Sciences
January 2019
Influenza Virus–Specific Human Antibody Repertoire Studies
The Journal of Immunology
January 2019
Role of antibody heavy and light chain interface residues in affinity maturation of bin...
Molecular Systems Design & Engineering
January 2019
Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with...
PLoS ONE
December 2018
Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vect...
Journal of Virology
December 2018
Current Understanding of Humoral Immunity to Enterovirus D68
Journal of the Pediatric Infectious Diseases Society
December 2018
Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses
Gastroenterology
December 2018
Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking ...
The Journal of Infectious Diseases
November 2018
Protective antibodies against Eastern equine encephalitis virus bind to epitopes in dom...
Nature Microbiology
November 2018
A protective human monoclonal antibody targeting the West Nile virus E protein preferen...
Nature Microbiology
November 2018
Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection
Cell Host & Microbe
November 2018
HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glyc...
Cell Host & Microbe
November 2018
In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against E...
Cell Reports
November 2018
Potent Neutralizing Human Monoclonal Antibodies Preferentially Target Mature Dengue Vir...
Journal of Virology
September 2018
Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and g...
PLoS Pathogens
August 2018
Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infecti...
The Journal of Infectious Diseases
August 2018
Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by V...
Cell Reports
August 2018
Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated fr...
Cell Reports
August 2018
A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against E...
Cell Host & Microbe
August 2018
Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features th...
Cell
August 2018
A multifunctional human monoclonal neutralizing antibody that targets a unique conserve...
Nature Communications
July 2018
Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in...
The Journal of Infectious Diseases
July 2018
Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the...
Immunity
July 2018
Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public...
Cell Host & Microbe
June 2018
Broadly neutralizing antibodies from human survivors target a conserved site in the Ebo...
Nature Microbiology
May 2018
Mxra8 is a receptor for multiple arthritogenic alphaviruses
Nature
May 2018
Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes o...
mBio
February 2018
Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins
PLoS Pathogens
February 2018
Integrating linear optimization with structural modeling to increase HIV neutralization...
PLoS Computational Biology
February 2018
OUP accepted manuscript
The Journal of Infectious Diseases
January 2018
The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site ...
Cell Host & Microbe
January 2018
Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent ...
Proceedings of the National Academy of Sciences
December 2017
Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody t...
Structure
December 2017
Structure–function characterization of three human antibodies targeting the vaccinia vi...
Journal of Biological Chemistry
November 2017
Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans
Journal of Virology
October 2017
Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-An...
Structure
September 2017
Immune correlates of protection for dengue: State of the art and research agenda
Vaccine
August 2017
Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design
Cell Host & Microbe
August 2017
Is It Possible to Develop a “Universal” Influenza Virus Vaccine?
Cold Spring Harbor Perspectives in Biology
June 2017
Therapeutic administration of a recombinant human monoclonal antibody reduces the sever...
PLoS Neglected Tropical Diseases
June 2017
Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance
JCI Insight
May 2017
Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a h...
Science Translational Medicine
April 2017
Treating Flu with Skin of Frog
Immunity
April 2017
A human antibody against Zika virus crosslinks the E protein to prevent infection
Nature Communications
March 2017
Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isola...
The Journal of Infectious Diseases
February 2017
Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus a...
Science Translational Medicine
February 2017
A novel pre-fusion conformation-specific neutralizing epitope on the respiratory syncyt...
Nature Microbiology
January 2017
Structural basis for antibody cross-neutralization of respiratory syncytial virus and h...
Nature Microbiology
January 2017
Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to Dengue Vir...
Journal of Virology
December 2016
Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice
Nature
November 2016
Structural basis for nonneutralizing antibody competition at antigenic site II of the r...
Proceedings of the National Academy of Sciences
October 2016
Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections
Cell
October 2016
Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody
Proceedings of the National Academy of Sciences
September 2016
A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses
Science
September 2016
Teaching a Clone to Walk, One Step at a Time
Cell
September 2016
Phenome-Wide Association Study to Explore Relationships between Immune System Related G...
PLoS ONE
August 2016
Structures of Ebola virus GP and sGP in complex with therapeutic antibodies
Nature Microbiology
August 2016
Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence
Cell Reports
August 2016
Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 E...
PLoS ONE
July 2016
Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 ...
The Journal of Immunology
July 2016
Recognition of influenza H3N2 variant virus by human neutralizing antibodies
JCI Insight
July 2016
Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Mon...
PLoS Pathogens
June 2016
Characterization of dengue virus 2 growth in megakaryocyte–erythrocyte progenitor cells
Virology
June 2016
Deep sequencing and human antibody repertoire analysis
Current Opinion in Immunology
June 2016
A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV
PLoS ONE
May 2016
Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Ep...
mSphere
May 2016
Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Know...
PLoS ONE
May 2016
Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody bac...
Proceedings of the National Academy of Sciences
April 2016
Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal An...
Journal of Virology
March 2016
H7N9 influenza virus neutralizing antibodies that possess few somatic mutations
Journal of Clinical Investigation
March 2016
Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealin...
mBio
February 2016
Low frequency of broadly neutralizing HIV antibodies during chronic infection even in q...
Molecular Immunology
February 2016
Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syn...
Vaccine
February 2016
Chimeric Filoviruses for Identification and Characterization of Monoclonal Antibodies
Journal of Virology
January 2016
Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effec...
Haematologica
January 2016
Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural...
Cell
January 2016
Development of Human Monoclonal Antibodies Against Respiratory Syncytial Virus Using a ...
January 2016
Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and ...
Cell
November 2015
Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing ...
Journal of Virology
October 2015
Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclon...
Proceedings of the National Academy of Sciences
October 2015
A New Quaternary Structure Epitope on Dengue Virus Serotype 2 Is the Target of Durable ...
mBio
October 2015
Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies wit...
Cell Host & Microbe
September 2015
Deciphering the human immunome
Expert Review of Vaccines
August 2015
Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibod...
PLoS ONE
August 2015
Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominan...
PLoS ONE
July 2015
Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the recept...
Proceedings of the National Academy of Sciences
July 2015
Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Ba...
PLoS Computational Biology
July 2015
Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E prot...
Science
July 2015
Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies wit...
Cell Host & Microbe
July 2015
Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during...
Journal of Biological Chemistry
June 2015
Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth
Journal of Clinical Investigation
May 2015
Retraction for Messer et al., Dengue virus envelope protein domain I/II hinge determine...
Proceedings of the National Academy of Sciences
May 2015
Challenges and Opportunities in Developing Respiratory Syncytial Virus Therapeutics
The Journal of Infectious Diseases
February 2015
A highly potent human antibody neutralizes dengue virus serotype 3 by binding across th...
Nature Communications
February 2015
Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus
Cell
February 2015
Structural Basis for Marburg Virus Neutralization by a Cross-Reactive Human Antibody
Cell
February 2015
Influenza Viruses with Receptor-Binding N1 Neuraminidases Occur Sporadically in Several...
Journal of Virology
January 2015
Antibodies for Infectious Diseases
January 2015
Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies
January 2015
Committing the Oldest Sins in the Newest Kind of Ways—Antibodies Targeting the Influenz...
January 2015
Identification of Residues in the Human Respiratory Syncytial Virus Fusion Protein That...
Journal of Virology
October 2014
Dengue Viruses Are Enhanced by Distinct Populations of Serotype Cross-Reactive Antibodi...
PLoS Pathogens
October 2014
Isolation of Dengue Virus-Specific Memory B Cells with Live Virus Antigen from Human Su...
Journal of Virology
August 2014
Intracellular neutralization of a virus using a cell-penetrating molecular transporter
Nanomedicine
August 2014
Tissue-Specific Expressed Antibody Variable Gene Repertoires
PLoS ONE
June 2014
STAT4 Deficiency Fails To Induce Lung Th2 or Th17 Immunity following Primary or Seconda...
Journal of Virology
June 2014
Correction for Messer et al., Dengue virus envelope protein domain I/II hinge determine...
Proceedings of the National Academy of Sciences
April 2014
Escape from neutralization by the respiratory syncytial virus-specific neutralizing mon...
Virology
April 2014
Antibody Engineering and Therapeutics
mAbs
March 2014
Proof of principle for epitope-focused vaccine design
Nature
February 2014
Combining Single RNA Sensitive Probes with Subdiffraction-Limited and Live-Cell Imaging...
ACS Nano
January 2014
Diagnostic errors in interpretation of pediatric musculoskeletal radiographs at common ...
Pediatric Radiology
January 2014
Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific...
Proceedings of the National Academy of Sciences
January 2014
A potent anti-dengue human antibody preferentially recognizes the conformation of E pro...
EMBO Molecular Medicine
January 2014
Paramyxoviruses: Respiratory Syncytial Virus and Human Metapneumovirus
January 2014
The Potent and Broadly Neutralizing Human Dengue Virus-Specific Monoclonal Antibody 1C1...
mBio
November 2013
Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses
Journal of Clinical Investigation
November 2013
Differential Accessibility of a Rotavirus VP6 Epitope in Trimers Comprising Type I, II,...
Journal of Virology
October 2013
Impact of new sequencing technologies on studies of the human B cell repertoire
Current Opinion in Immunology
October 2013
Intermittent Testicular Torsion in the Pediatric Patient: Sonographic Indicators of a D...
American Journal of Roentgenology
October 2013
Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Bindin...
Journal of Virology
September 2013
Exposure to Family Members: Infections and Recent Live Vaccinations
September 2013
Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses
Journal of Clinical Investigation
September 2013
Universal Flu Vaccines: Primum non nocere
Science Translational Medicine
August 2013
Gold nanorod vaccine for respiratory syncytial virus
Nanotechnology
June 2013
Anti Rotavirus Antibody
May 2013
Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding...
PLoS ONE
May 2013
Crowdsourcing Immunity
Science
May 2013
Human Germline Antibody Gene Segments Encode Polyspecific Antibodies
PLoS Computational Biology
April 2013
E107 Complexity of human naïve B cell repertoires
JAIDS Journal of Acquired Immune Deficiency Syndromes
April 2013
Discovering naturally processed antigenic determinants that confer protective T cell im...
Journal of Clinical Investigation
April 2013
Human Monoclonal Antibodies Derived From Memory B Cells Following Live Attenuated Dengu...
The Journal of Infectious Diseases
March 2013
Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monocl...
mAbs
March 2013
Reversion of Somatic Mutations of the Respiratory Syncytial Virus-Specific Human Monocl...
The Journal of Immunology
March 2013
A recurring motif for antibody recognition of the receptor-binding site of influenza he...
Nature Structural & Molecular Biology
February 2013
Secondary mechanisms of diversification in the human antibody repertoire
Frontiers in Immunology
January 2013
Molecular mechanisms driving respiratory syncytial virus assembly
Future Microbiology
January 2013
Respiratory Syncytial Virus Regulates Human MicroRNAs by Using Mechanisms Involving Bet...
mBio
December 2012
Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and ...
PLoS Pathogens
December 2012
A stabilized respiratory syncytial virus reverse genetics system amenable to recombinat...
Virology
December 2012
Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival
Experimental Hematology
December 2012
Unusual Features of Vaccinia Virus Extracellular Virion Form Neutralization Resistance ...
Journal of Virology
November 2012
Erratum: Corrigendum: Neutralizing antibodies derived from the B cells of 1918 influenz...
Nature
September 2012
A Chemically Programmed Antibody Is a Long-Lasting and Potent Inhibitor of Influenza Ne...
ChemBioChem
September 2012
Frequency and genetic characterization of V(DD)J recombinants in the human peripheral b...
Immunology
August 2012
Influenza Virus Resistance to Human Neutralizing Antibodies
mBio
July 2012
Respiratory Syncytial Virus Assembles into Structured Filamentous Virion Particles Inde...
PLoS ONE
July 2012
Location and length distribution of somatic hypermutation-associated DNA insertions and...
Genes and Immunity
June 2012
High-throughput antibody sequencing reveals genetic evidence of global regulation of th...
Genes and Immunity
May 2012
Human Respiratory Syncytial Virus Nucleoprotein and Inclusion Bodies Antagonize the Inn...
Journal of Virology
May 2012
Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Origina...
PLoS ONE
May 2012
Identification of human neutralizing antibodies that bind to complex epitopes on dengue...
Proceedings of the National Academy of Sciences
April 2012
Human Monoclonal Antibodies to Pandemic 1957 H2N2 and Pandemic 1968 H3N2 Influenza Viruses
Journal of Virology
March 2012
Structure of the human metapneumovirus fusion protein with neutralizing antibody identi...
Nature Structural & Molecular Biology
March 2012
A Critical Phenylalanine Residue in the Respiratory Syncytial Virus Fusion Protein Cyto...
mBio
February 2012
Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implic...
Blood
January 2012
Independent Structural Domains in Paramyxovirus Polymerase Protein
Journal of Biological Chemistry
January 2012
Viral Pneumonia
January 2012
Persistence of Circulating Memory B Cell Clones with Potential for Dengue Virus Disease...
Journal of Virology
December 2011
Identification of potential human respiratory syncytial virus and metapneumovirus T cel...
Journal of Immunological Methods
November 2011
Machine learning competition in immunology – Prediction of HLA class I binding peptides
Journal of Immunological Methods
November 2011
Maturation-Induced Cloaking of Neutralization Epitopes on HIV-1 Particles
PLoS Pathogens
September 2011
Epitope-Specific Human Influenza Antibody Repertoires Diversify by B Cell Intraclonal S...
The Journal of Immunology
August 2011
A Broadly Neutralizing Human Monoclonal Antibody That Recognizes a Conserved, Novel Epi...
Journal of Virology
August 2011
Tribute to David T. Karzon, MD and Robert M. Chanock, MD
Vaccine
May 2011
Activation of protein kinase R is required for induction of stress granules by respirat...
Virology
April 2011
An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Functio...
mBio
February 2011
Research Highlights
Nanomedicine
January 2011
Human Metapneumovirus
January 2011
Respiratory Syncytial Virus
January 2011
Prevention of Fetal and Early Life Infections Through Maternal–Neonatal Immunization
January 2011
Respiratory Syncytial Virus and Human Metapneumovirus
January 2011
Reply to Schlapbach et al
The Journal of Infectious Diseases
December 2010
Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes
news nature com
December 2010
Specificity for Human Hemoglobin Enhances Staphylococcus aureus Infection
Cell Host & Microbe
December 2010
Faculty of 1000 evaluation for A size threshold limits prion transmission and establish...
October 2010
Transforming Growth Factor Beta Is a Major Regulator of Human Neonatal Immune Responses...
Journal of Virology
October 2010
Respiratory Syncytial Virus Induces Host RNA Stress Granules To Facilitate Viral Replic...
Journal of Virology
September 2010
Surfing a genetic association interaction network to identify modulators of antibody re...
Genes and Immunity
July 2010
Pseudovirion Particles Bearing Native HIV Envelope Trimers Facilitate a Novel Method fo...
JAIDS Journal of Acquired Immune Deficiency Syndromes
July 2010
Population‐Based Incidence of Human Metapneumovirus Infection among Hospitalized Children
The Journal of Infectious Diseases
June 2010
Regulatory T cell expression of CLA or α4β7 and skin or gut acute GVHD outcomes
Bone Marrow Transplantation
May 2010
Emerging studies of human HIV-specific antibody repertoires
Vaccine
May 2010
Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus
Science
March 2010
Naturally Occurring Human Monoclonal Antibodies Neutralize both 1918 and 2009 Pandemic ...
Journal of Virology
December 2009
Faculty of 1000 evaluation for Motavizumab for prophylaxis of respiratory syncytial vir...
December 2009
Faculty of 1000 evaluation for Crystal structure of a nucleocapsid-like nucleoprotein-R...
December 2009
Recent advances in the study of human antibody responses to influenza virus using optim...
Vaccine
December 2009
The human neonatal B cell response to respiratory syncytial virus uses a biased antibod...
Molecular Immunology
December 2009
Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years
Virology Journal
September 2009
Faculty of 1000 evaluation for Broad and potent neutralizing antibodies from an African...
September 2009
The Pediatric Burden of Human Coronaviruses Evaluated for Twenty Years
The Pediatric Infectious Disease Journal
August 2009
Coronavirus infection and hospitalizations for acute respiratory illness in young children
Journal of Medical Virology
May 2009
Single molecule–sensitive probes for imaging RNA in live cells
Nature Methods
April 2009
Amphiregulin-Deficient Mice Develop Spasmolytic Polypeptide Expressing Metaplasia and I...
Gastroenterology
April 2009
Capturing the Spectrum of Interaction Effects in Genetic Association Studies by Simulat...
PLoS Genetics
March 2009
Faculty of 1000 evaluation for Antibody recognition of a highly conserved influenza vir...
March 2009
Faculty of 1000 evaluation for Antigen-specific human polyclonal antibodies from hyperi...
February 2009
Faculty of 1000 evaluation for Estrogen directly activates AID transcription and function.
February 2009
A Chimeric A2 Strain of Respiratory Syncytial Virus (RSV) with the Fusion Protein of RS...
Journal of Virology
February 2009
Faculty of 1000 evaluation for Engineering microRNA responsiveness to decrease virus pa...
November 2008
Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal...
Journal of General Virology
October 2008
Integrated analysis of genetic and proteomic data identifies biomarkers associated with...
Genes and Immunity
October 2008
An Alphavirus Replicon-Based Human Metapneumovirus Vaccine Is Immunogenic and Protectiv...
Journal of Virology
September 2008
Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncyti...
Vaccine
September 2008
Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors
Nature
August 2008
Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab...
Proceedings of the National Academy of Sciences
July 2008
Genetic Basis for Adverse Events after Smallpox Vaccination
The Journal of Infectious Diseases
July 2008
An optimized electrofusion-based protocol for generating virus-specific human monoclona...
Journal of Immunological Methods
July 2008
Functional Maturation of the Human Antibody Response to Rotavirus
The Journal of Immunology
March 2008
Immunodominance of the VH1-46 Antibody Gene Segment in the Primary Repertoire of Human ...
The Journal of Immunology
February 2008
A Clinical Isolate Strain of Respiratory Syncytial Virus (RSV) Causes Airway Obstructio...
Journal of Allergy and Clinical Immunology
February 2008
Human Metapneumovirus
January 2008
Respiratory Syncytial Virus
January 2008
Faculty of 1000 evaluation for Duration of humoral immunity to common viral and vaccine...
November 2007
Faculty of 1000 evaluation for Palivizumab prophylaxis, respiratory syncytial virus, an...
October 2007
Faculty of 1000 evaluation for A multicenter, randomized, controlled trial of dexametha...
October 2007
Venezuelan Equine Encephalitis Virus Replicon Particles Encoding Respiratory Syncytial ...
Journal of Virology
October 2007
Genetic Predisposition for Adverse Events after Vaccination
The Journal of Infectious Diseases
July 2007
Evaporative cooling feature selection for genotypic data involving interactions
Bioinformatics
June 2007
A Recombinant Human Monoclonal Antibody to Human Metapneumovirus Fusion Protein That Ne...
Journal of Virology
May 2007
Evidence for preferential Ig gene usage and differential TdT and exonuclease activities...
Molecular Immunology
March 2007
Faculty of 1000 evaluation for Ab and T cell epitopes of influenza A virus, knowledge a...
February 2007
Using the natural evolution of a rotavirus-specific human monoclonal antibody to predic...
Immunome Research
January 2007
Towards a consensus on datasets and evaluation metrics for developing B-cell epitope pr...
Journal of Molecular Recognition
January 2007
Tissue-Specific Regulation of CD8+ T-Lymphocyte Immunodominance in Respiratory Syncytia...
Journal of Virology
December 2006
Faculty of 1000 evaluation for The histopathology of fatal untreated human respiratory ...
December 2006
Faculty of 1000 evaluation for Targeted killing of virally infected cells by radiolabel...
December 2006
Nanoscale tools for rapid and sensitive diagnosis of viruses
Future Virology
November 2006
Faculty of 1000 evaluation for Low-coverage vaccination strategies for the conservation...
October 2006
Human Metapneumovirus Fusion Protein Vaccines That Are Immunogenic and Protective in Co...
Journal of Virology
October 2006
Examination of a Fusogenic Hexameric Core from Human Metapneumovirus and Identification...
Journal of Virology
October 2006
Introduction
Seminars in Pediatric Infectious Diseases
October 2006
Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling vi...
Immunology
September 2006
Feature Selection using a Random Forests Classifier for the Integrated Analysis of Mult...
September 2006
Cellular Immune Responses to Diluted and Undiluted Aventis Pasteur Smallpox Vaccine
The Journal of Infectious Diseases
August 2006
Cytokine Expression Patterns Associated with Systemic Adverse Events following Smallpox...
The Journal of Infectious Diseases
August 2006
Faculty of 1000 evaluation for A potential molecular mechanism for hypersensitivity cau...
July 2006
Faculty of 1000 evaluation for Human monoclonal antibody combination against SARS coron...
July 2006
:Vaccines: Frontiers in Design and Development
Clinical Infectious Diseases
July 2006
Automated image analysis of atomic force microscopy images of rotavirus particles
Ultramicroscopy
June 2006
Hybrid grammar-based approach to nonlinear dynamical system identification from biologi...
Physical Review E
February 2006
Detection of viral infections using colloidal quantum dots
February 2006
The Role of Human Metapneumovirus in Upper Respiratory Tract Infections in Children: A ...
The Journal of Infectious Diseases
February 2006
The Transmembrane Domain of the Respiratory Syncytial Virus F Protein Is an Orientation...
Journal of Virology
February 2006
Viral Pneumonia
January 2006
Rotavirus-Specific CD5+ B Cells in Young Children Exhibit a Distinct Antibody Repertoir...
Human Immunology
January 2006
Reply
Journal of Allergy and Clinical Immunology
January 2006
Transcriptional Control of Activation-Induced Cytidine Deaminase and Error-Prone DNA Po...
Human Immunology
January 2006
Faculty of 1000 evaluation for Altered TCR signaling from geometrically repatterned imm...
November 2005
Human Metapneumovirus Infection Plays an Etiologic Role in Acute Asthma Exacerbations R...
The Journal of Infectious Diseases
October 2005
The Transmembrane Domain of the Respiratory Syncytial Virus F Protein Is an Orientation...
Journal of Virology
October 2005
Prospective Study of the Incidence, Clinical Features, and Outcome of Symptomatic Upper...
Biology of Blood and Marrow Transplantation
October 2005
A Prospective Study Comparing Human Metapneumovirus with Other Respiratory Viruses in A...
The Journal of Infectious Diseases
September 2005
The Cotton Rat (Sigmodon hispidus) Is a Permissive Small Animal Model of Human Metapneu...
Journal of Virology
September 2005
Identification of an H-2Db-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix...
Virology
July 2005
Faculty of 1000 evaluation for Treatment of ulcerative colitis with a humanized antibod...
June 2005
Human metapneumovirus infection in children hospitalized for wheezing
Journal of Allergy and Clinical Immunology
June 2005
Natural Evolution of a Human Virus-Specific Antibody Gene Repertoire by Somatic Hypermu...
Human Immunology
June 2005
Faculty of 1000 evaluation for Stable antibody expression at therapeutic levels using t...
May 2005
Faculty of 1000 evaluation for Serum IgG mediates mucosal immunity against rotavirus in...
May 2005
Pseudovirion Particle Production by Live Poxvirus Human Immunodeficiency Virus Vaccine ...
Journal of Virology
May 2005
Prevalence of Reovirus‐Specific Antibodies in Young Children in Nashville, Tennessee
The Journal of Infectious Diseases
April 2005
Application of semiconductor fluorescent nanocrystals as optical probes for rapid early...
April 2005
Progression of Respiratory Syncytial Virus Infection Monitored by Fluorescent Quantum D...
Nano Letters
April 2005
Differential Regulation of Granzyme and Perforin in Effector and Memory T Cells followi...
The Journal of Immunology
March 2005
VH1-46 Is the Dominant Immunoglobulin Heavy Chain Gene Segment in Rotavirus-Specific Me...
The Journal of Immunology
March 2005
Smallpox Vaccination Does Not Elevate Systemic Levels of Prothrombotic Proteins Associa...
The Journal of Infectious Diseases
March 2005
Faculty of 1000 evaluation for Are anticapsular antibodies the primary mechanism of pro...
February 2005
Cooperativity of actin and microtubule elements during replication of respiratory syncy...
Virology
January 2005
Introduction
The Pediatric Infectious Disease Journal
November 2004
Human Metapneumovirus as a Major Cause of Human Respiratory Tract Disease
The Pediatric Infectious Disease Journal
November 2004
Vaccination Success Rate and Reaction Profile With Diluted and Undiluted Smallpox Vaccine
JAMA
September 2004
Faculty of 1000 evaluation for A role for Streptococcus pneumoniae in virus-associated ...
July 2004
Faculty of 1000 evaluation for An efficient method to make human monoclonal antibodies ...
July 2004
Human Metapneumovirus and Lower Respiratory Tract Disease in Children
New England Journal of Medicine
April 2004
Adverse Events after Smallpox Immunizations Are Associated with Alterations in Systemic...
The Journal of Infectious Diseases
April 2004
Effect of Zinc Salts on Respiratory Syncytial Virus Replication
Antimicrobial Agents and Chemotherapy
March 2004
Faculty of 1000 evaluation for Tyrosine sulfation of human antibodies contributes to re...
February 2004
Human Metapneumovirus and Lower Respiratory Tract Disease in Otherwise Healthy Infants ...
New England Journal of Medicine
January 2004
B-Cell Development
January 2004
Apical recycling systems regulate directional budding of respiratory syncytial virus fr...
Proceedings of the National Academy of Sciences
November 2003
Fatal Hemophagocytic Lymphohistiocytosis Associated with Epstein-Barr Virus Infection i...
Clinical Infectious Diseases
November 2003
Infant and Adult Human B Cell Responses to Rotavirus Share Common Immunodominant Variab...
The Journal of Immunology
October 2003
Faculty of 1000 evaluation for Antibody domain exchange is an immunological solution to...
July 2003
Respiratory Syncytial Virus Nucleoprotein-Specific Cytotoxic T-Cell Epitopes in a South...
Journal of Virology
July 2003
Immunology of viral respiratory tract infection in infancy
Paediatric Respiratory Reviews
June 2003
CD154 Regulates Primate Humoral Immunity to Influenza
American Journal of Transplantation
June 2003
Planar growth faults in double-layered or triple-layered (Ca,Sr)-ruthenate single cryst...
Journal of Crystal Growth
May 2003
Faculty of 1000 evaluation for Combinatorial immunoglobulin light chain variability cre...
April 2003
Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyt...
Immunology
April 2003
Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-...
Journal of Immunological Methods
April 2003
Faculty of 1000 evaluation for Mortality associated with influenza and respiratory sync...
January 2003
Faculty of 1000 evaluation for Respiratory syncytial virus-induced activation of nuclea...
November 2002
Faculty of 1000 evaluation for A common haplotype of interleukin-4 gene IL4 is associat...
November 2002
Faculty of 1000 evaluation for Chimeric IgA antibodies against HLA class II effectively...
November 2002
The Human Polymeric Immunoglobulin Receptor Facilitates Invasion of Epithelial Cells by...
Infection and Immunity
September 2002
PNEUMOCYSTIS CARINII PNEUMONIA IN A GIRL WITH A MIDBRAIN GLIOMA
Pediatric Hematology and Oncology
January 2002
Influence of Maternal Antibodies on Neonatal Immunization against Respiratory Viruses
Clinical Infectious Diseases
November 2001
Respiratory syncytial virus vaccine development
Vaccine
October 2001
Passively Acquired Antibodies Suppress Humoral But Not Cell-Mediated Immunity in Mice I...
The Journal of Immunology
October 2001
CD40-Ligand in Primate Cardiac Allograft and Viral Immunity
Immunologic Research
January 2001
Genetic and Structural Determinants of Virus Neutralizing Antibodies
Immunologic Research
January 2001
Recurrent Achromobacter xylosoxidans Bacteremia Associated with Persistent Lymph Node I...
Clinical Infectious Diseases
November 2000
Recurrent Pneumococcal Arthritis as the Presenting Manifestation of X-Linked Agammaglob...
Clinical Infectious Diseases
November 2000
Aktuelle Ansätze zur Impfstoffentwicklung gegen Respiratory-Syncytial-Virus (RSV)
Monatsschrift Kinderheilkunde
November 2000
Evaluation of a Live, Cold‐Passaged, Temperature‐Sensitive, Respiratory Syncytial Virus...
The Journal of Infectious Diseases
November 2000
A RhoA-derived peptide inhibits syncytium formation induced by respiratory syncytial vi...
news nature com
January 2000
Passive IgA Monoclonal Antibody Is No More Effective Than IgG at Protecting Mice from M...
The Journal of Infectious Diseases
October 1999
The live attenuated subgroup B respiratory syncytial virus vaccine candidate RSV 2B33F ...
Virus Research
January 1999
Monoclonal Antibody-Resistant Mutants Selected with a Respiratory Syncytial Virus-Neutr...
Virology
December 1998
Immune responses of infants to infection with respiratory viruses and live attenuated r...
Vaccine
August 1998
Isolation of a Second Recombinant Human Respiratory Syncytial Virus Monoclonal Antibody...
The Journal of Infectious Diseases
April 1998
Evaluation of a Live, Attenuated Respiratory Syncytial Virus (RSV)Vaccine Candidate, cp...
Pediatric Research
April 1998
Evaluation of Two Live, Cold‐Passaged, Temperature‐Sensitive Respiratory Syncytial Viru...
The Journal of Infectious Diseases
December 1997
Nucleotide Sequence Analysis of the Respiratory Syncytial Virus Subgroup A Cold-Passage...
Virology
November 1996
The role of antibodies in respiratory viral immunity
Seminars in Virology
August 1996
Live Subgroup B Respiratory Syncytial Virus Vaccines that Are Attenuated, Genetically S...
The Journal of Infectious Diseases
April 1996
Acquisition of the ts phenotype by a chemically mutagenized cold-passaged human respira...
Virus Genes
January 1996
Cold-passaged, temperature-sensitive mutants of human respiratory syncytial virus (RSV)...
Vaccine
June 1995
A Cold-Passaged, Attenuated Strain of Human Respiratory Syncytial Virus Contains Mutati...
Virology
April 1995
Isolation and characterization of a highly attenuated respiratory syncytial virus (RSV)...
Vaccine
January 1995
Current approaches to the development of vaccines against disease caused by respiratory...
Vaccine
January 1995
An update on approaches to the development of respiratory syncytial virus (RSV) and par...
Virus Research
April 1994
Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effectiv...
Proceedings of the National Academy of Sciences
February 1994
A further attenuated derivative of a cold-passaged temperature-sensitive mutant of huma...
Vaccine
January 1994
Satisfactorily attenuated and protective mutants derived from a partially attenuated co...
Vaccine
January 1994
A comparison in chimpanzees of the immunogenicity and efficacy of live attenuated respi...
Vaccine
January 1993
Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory...
Proceedings of the National Academy of Sciences
November 1992
