All Stories

  1. A human IgM enriched immunoglobulin preparation, Pentaglobin, reverses autoimmune diabetes without immune suppression in NOD mice
  2. Vascular alterations impede fragile tolerance to pregnancy in type 1 diabetes
  3. Diabetes Triples COVID-19 Severity: A Prospective Analysis
  4. Physician-Scientist Training and Programming in Pediatric Residency Programs: A National Survey
  5. Deep learning-based pancreas volume assessment in individuals with type 1 diabetes
  6. Letter to the Editor From Gregory and Moore: “Age and Hospitalization Risk in People With Type 1 Diabetes and COVID-19: Data From the T1D Exchange Surveillance Study”
  7. GBS infection in pregnant and non-pregnant women with diabetes mellitus
  8. Metabolic preconditioning in CD4+ T cells restores inducible immune tolerance in lupus-prone mice
  9. Development of a standardized MRI protocol for pancreas assessment in humans
  10. High-Throughput Detection of Autoantigen-Specific B Cells Among Distinct Functional Subsets in Autoimmune Donors
  11. Response to Comment on Gregory et al. COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic’s Impact in Type 1 and Type 2 Diabetes. Diabetes Care 2021;44:526–532
  12. The Dual Burden of Type 1 Diabetes and COVID-19
  13. The Rapid Transition to Telemedicine and Its Effect on Access to Care for Patients With Type 1 Diabetes During the COVID-19 Pandemic
  14. Perspectives from the Society for Pediatric Research: advice on sustaining science and mentoring during COVID-19
  15. COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic’s Impact in Type 1 and Type 2 Diabetes
  16. The Peripheral Peril: Injected Insulin Induces Insulin Insensitivity in Type 1 Diabetes
  17. A Special Thanks to the Reviewers of Diabetes
  18. Fixing the leaky pipeline: identifying solutions for improving pediatrician-scientist training during pediatric residency
  19. Repeatability and Reproducibility of Pancreas Volume Measurements Using MRI
  20. Correlating maternal iodine status with neonatal thyroid function in two hospital populations in Ghana: a multicenter cross-sectional pilot study
  21. Regulation of Diabetogenic Immunity by IL-15–Activated Regulatory CD8 T Cells in Type 1 Diabetes
  22. 185-LB: Repeatability and Reproducibility of Pancreas Volume Measurements Using MRI
  23. Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison to GCK-MODY (MODY2)
  24. B lymphocytes protect islet β cells in diabetes-prone NOD mice treated with imatinib
  25. Pancreas Volume Declines During the First Year After Diagnosis of Type 1 Diabetes and Exhibits Altered Diffusion at Disease Onset
  26. Distinct mucosal microbial communities in infants with surgical necrotizing enterocolitis correlate with age and antibiotic exposure
  27. Cutting Edge: IL-1α and Not IL-1β Drives IL-1R1–Dependent Neonatal Murine Sepsis Lethality
  28. Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis
  29. Supplementation of p40, a Lactobacillus rhamnosus GG-derived protein, in early life promotes epidermal growth factor receptor-dependent intestinal development and long-term health outcomes
  30. Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice
  31. Identification of a gene-expression predictor for diagnosis and personalized stratification of lupus patients
  32. Limited achievement of NIH research independence by pediatric K award recipients
  33. Bacterial DNA is present in the fetal intestine and overlaps with that in the placenta in mice
  34. Pancreas Volume Declines over the First Year after Diagnosis with Type 1 Diabetes (T1D)
  35. In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4+ T Lymphocytes
  36. Timing of Meal Insulin and Its Relation to Adherence to Therapy in Type 1 Diabetes
  37. Host Expression of the CD8 Treg/NK Cell Restriction Element Qa-1 is Dispensable for Transplant Tolerance
  38. Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition
  39. ERAD-icating mutant insulin promotes functional insulin secretion
  40. An overview of the necessary thymic contributions to tolerance in transplantation
  41. Grave effects of a specific immune therapy
  42. Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation
  43. The inflammasome keeps on breaking your heart
  44. New onset diabetes mellitus after heart transplantation in children is a common but potentially modifiable burden
  45. Sympathy for low blood sugar is felt in your gut
  46. Viral infection crosses up antigen presentation to drive autoimmunity
  47. Use of the Electronic Medical Record to Assess Pancreas Size in Type 1 Diabetes
  48. Activation of Human T Cells in Hypertension
  49. An LGG-derived protein promotes IgA production through upregulation of APRIL expression in intestinal epithelial cells
  50. Who knows best—your mother or her microbiome?
  51. Sex (steroids) is in the AIRE
  52. Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18
  53. Neonatal colonization of mice with LGG promotes intestinal development and decreases susceptibility to colitis in adulthood
  54. Limited diversity sparks inflammation at the mucosal border
  55. Lupus‐Prone Mice Resist Immune Regulation and Transplant Tolerance Induction
  56. Neonatal CD71+ Erythroid Cells Do Not Modify Murine Sepsis Mortality
  57. A Review of Adolescent Adherence in Type 1 Diabetes and the Untapped Potential of Diabetes Providers to Improve Outcomes
  58. Regulation of B lymphocyte responses to Toll-like receptor ligand binding during diabetes prevention in non-obese diabetic (NOD) mice
  59. The “Genomic Storm” Induced by Bacterial Endotoxin Is Calmed by a Nuclear Transport Modifier That Attenuates Localized and Systemic Inflammation
  60. Dysregulation of T Lymphocyte Proliferative Responses in Autoimmunity
  61. An immunosufficient murine model for the study of human islets
  62. Small Intestinal Intraepithelial TCRγδ+ T Lymphocytes Are Present in the Premature Intestine but Selectively Reduced in Surgical Necrotizing Enterocolitis
  63. Early life establishment of site-specific microbial communities in the gut
  64. Clinical predictors of autoimmune and severe atopic disease in pediatric heart transplant recipients
  65. The Prediction of Type 1 Diabetes by Multiple Autoantibody Levels and Their Incorporation Into an Autoantibody Risk Score in Relatives of Type 1 Diabetic Patients
  66. The Effects of Inpatient Hybrid Closed-Loop Therapy Initiated Within 1 Week of Type 1 Diabetes DiagnosisDiabetes Research in Children Network (DirecNet) and Type 1 Diabetes TrialNet Study Groups
  67. Type 1 Diabetes Mellitus
  68. Mechanisms of regulatory T cell counter-regulation by innate immunity
  69. Nuclear Transport Modulation Reduces Hypercholesterolemia, Atherosclerosis, and Fatty Liver
  70. Bioluminescence Imaging Reveals Dynamics of Beta Cell Loss in the Non-Obese Diabetic (NOD) Mouse Model
  71. Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials
  72. Clinical assessment of HNF1A and GCK variants and identification of a novel mutation causing MODY2
  73. Regulatory properties of the intestinal microbiome effecting the development and treatment of diabetes
  74. Zinc Transporter-8 Autoantibodies Improve Prediction of Type 1 Diabetes in Relatives Positive for the Standard Biochemical Autoantibodies
  75. Cutting Edge: The “Death” Adaptor CRADD/RAIDD Targets BCL10 and Suppresses Agonist-Induced Cytokine Expression in T Lymphocytes
  76. Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios
  77. Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity
  78. A Correction to the Research Article Titled: "Inhibition of Transplantation Tolerance by Immune Senescence Is Reversed by Endocrine Modulation" by G. Zhao, D. J. Moore, J. I. Kim, K. M. Lee, M. R. O'Connor, P. E. Duff, M. Yang, J. Lei, J. F. Markmann, ...
  79. Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial
  80. Autoimmune Alternating Hypo- and Hyperthyroidism in Children
  81. Inhibition of Transplantation Tolerance by Immune Senescence Is Reversed by Endocrine Modulation
  82. Can technological solutions for diabetes replace islet cell function?
  83. In Vivo Islet Protection by a Nuclear Import Inhibitor in a Mouse Model of Type 1 Diabetes
  84. An Unexpected Counter-Regulatory Role of IL-10 in B-Lymphocyte-Mediated Transplantation Tolerance
  85. Incorporating Type 1 Diabetes Prevention Into Clinical Practice
  86. Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival
  87. Accounting for chance in the calculus of autoimmune disease
  88. Regulatory T-Cell Counter-Regulation by Innate Immunity Is a Barrier to Transplantation Tolerance
  89. GITR Blockade Facilitates Treg Mediated Allograft Survival
  90. Reduced Diabetes in btk-Deficient Nonobese Diabetic Mice and Restoration of Diabetes with Provision of an Anti-Insulin IgH Chain Transgene
  91. Resolving the Conundrum of Islet Transplantation by Linking Metabolic Dysregulation, Inflammation, and Immune Regulation
  92. A direct comparison of rejection by CD8 and CD4 T cells in a transgenic model of allotransplantation
  93. Inhibition of ICAM-1/LFA-1 Interactions Prevents B-Cell-Dependent Anti-CD45RB-Induced Transplantation Tolerance
  94. Progress Toward Antibody-Induced Transplantation Tolerance
  95. Avenues for immunomodulation and graft protection by gene therapy in transplantation
  96. T-reg Mediated Suppression of the Allograft Response in the Draining Lymph Node
  97. Posttransplantation Lymphoproliferative Disorder in Pediatric Recipients of Solid Organ Transplants: Timing and Location of Disease
  98. T-regs inhibit effector T cell accumulation to prolong allograft survival
  99. NOD B-cells Are Insufficient to Incite T-Cell-Mediated Anti-islet Autoimmunity
  100. Inhibition of ICAM-1/LFA-1 interaction prevents allograft tolerance induced by anti-CD45RB
  101. Resistance to anti-CD45RB-induced tolerance in NOD mice: mechanisms involved
  102. Promotion of Allograft Survival by CD4+CD25+ Regulatory T Cells: Evidence for In Vivo Inhibition of Effector Cell Proliferation
  103. Resistance to anti-CD45RB-induced tolerance in NOD mice: mechanisms involved
  104. Specialized CC-chemokine secretion by Th1 cells in destructive autoimmune myocarditis
  105. Vulnerability of allografts to rejection by MHC class II-restricted T-cell receptor transgenic mice1
  106. CD25+ Immunoregulatory CD4 T Cells Mediate Acquired Central Transplantation Tolerance
  107. Transgenic T cells persist in an adoptive transfer model of mouse liver transplantation tolerance
  108. Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice
  109. Activation and Association of the Tec Tyrosine Kinase with the Human Prolactin Receptor: Mapping of a Tec/Vav1-Receptor Binding Site
  110. Contribution of the Innate Immune System to Autoimmune Diabetes: A Role for the CR1/CR2 Complement Receptors
  111. MHC Class II alpha/beta Heterodimeric Cell Surface Molecules Expressed from a Single Proviral Genome
  112. Contribution of the Innate Immune System to Autoimmune Diabetes: A Role for the CR1/CR2 Complement Receptors