Current affiliation: MRC Toxicology UnitSubject: Medicine And Medical SciencesPrimary location: United Kingdom
Published in:PLoS ONEPublication date:2011-12-19
Published in:Molecular and Cellular BiologyPublication date:2004-10-27
Published in:Not availablePublication date:2012-04-11
Published in:NeuropharmacologyPublication date:2014-02-01
Published in:Nature CommunicationsPublication date:2014-07-24
Published in:Cell Death and DiseasePublication date:2013-01-01
Published in:Cell Death and DiseasePublication date:2014-04-17
Published in:NaturePublication date:2007-09-30
Published in:Human Molecular GeneticsPublication date:2010-12-06
Published in:Cell Death and DiseasePublication date:2013-10-24
Published in:Cell Death and DifferentiationPublication date:2009-03-13
Published in:NaturePublication date:2014-01-19
We show that vitamin B9 (folic acid) protects neurons in models (flies and human cells) of Parkinson's disease
Published in:Cell Death and DiseasePublication date:2010-08-01
Published in:Journal of Cell SciencePublication date:2012-12-21
Published in:Cell Death and DifferentiationPublication date:2012-02-03
Published in:PLoS ONEPublication date:2013-12-30
Published in:Cell Death and DiseasePublication date:2016-06-23
Some inherited forms of early-onset Parkinson’s disease have typically been blamed on poorly functioning mitochondria, the powerhouses of cells. Wi...
Published in:Handbook of Proteolytic EnzymesPublication date:2013-01-01
Published in:NeurodegenerationPublication date:2012-04-11
Published in:Cell Death and DifferentiationPublication date:2011-06-24
Published in:International Journal of Cell BiologyPublication date:2012-01-01
Published in:Cell Death and DiseasePublication date:2012-06-01
Published in:Experimental Cell ResearchPublication date:2010-04-01
Published in:Cell Death and DifferentiationPublication date:2008-11-21
Published in:Journal of Neuropathology & Experimental NeurologyPublication date:2008-10-01
Published in:Molecular CellPublication date:2005-06-01
Published in:Human Molecular GeneticsPublication date:2005-06-16
Published in:Journal of Biological ChemistryPublication date:2003-09-25
Published in:Cell Death and DifferentiationPublication date:2002-07-01
Published in:Current Protocols in Cell BiologyPublication date:2001-08-01
Published in:Annual Review of BiochemistryPublication date:1999-06-01
Published in:Current BiologyPublication date:1999-09-01
Published in:Apoptosis in NeurobiologyPublication date:1998-12-24
Published in:Biology OpenPublication date:2016-12-23
We show that fly food with increased levels of vitamin B3 rescues mitochondrial defects and has neuroprotective effects in a fly model of Parkinson...
Published in:Cell Death and DiseasePublication date:2016-03-31
We show that flies kept on a diet supplemented with vitamin B3 are protected from the neurotoxic consequences of mitochondrial defects in a model o...
Published in:MattersPublication date:2016-12-19
Paraquat, an herbicide used to treat crops had been linked to Parkinson's disease. This study explores the metabolism of human neurons exposed to t...
Published in:Cell Death and DifferentiationPublication date:2017-02-17
Boosting genes that affect the metabolism of nucleotides in mitochondria can protect neurons that are affected in Parkinson’s disease.
Published in:MattersPublication date:2017-03-09
The study suggests that folinic acid, which is used in medications to treat bowel cancer, can also protect dying neurons associated with Parkinson’...
Published in:MattersPublication date:2017-07-21
We used a chemical method (a PNA clamp) to improve the detection of mutations in KRAS. Mutations in KRAS are associated with cancers that are diffi...