What is it about?

The study, published in the journal Disease Models and Mechanisms, found that in preliminary tests using mice, a blood test could measure the circulating levels of DNA in the blood which cancer cells shed as they grow and multiply, and could even predict the presence of tumours in the lungs before they became cancerous

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Why is it important?

This observation is exciting because it suggests that tumour-causing mutations may be detectable in circulating DNA from patients with early-stage cancers or with pre-cancerous tumours

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This page is a summary of: Early detection of pre-malignant lesions in a KRASG12D-driven mouse lung cancer model by monitoring circulating free DNA, Disease Models & Mechanisms, February 2019, The Company of Biologists,
DOI: 10.1242/dmm.036863.
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