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  1. Phenotypic, proteomic, and functional analyses of cytokine-induced memory-like NK cells show two distinct subsets based on CD16 expression

    Article • Scientific Reports, October 2025, Springer Science + Business Media

    Dr Javier G Casado

  2. Implementation of LABSTER virtual lab in immunology for innovative teaching and improved learning in veterinary degree

    Article • Frontiers in Veterinary Science, August 2025, Frontiers

    Dr Javier G Casado

  3. Influence of secretome from porcine cardiosphere-derived cells on porcine macrophage polarization and their possible implications for cardiac remodeling post-myocardial infarction in vitro

    Article • Frontiers in Cell and Developmental Biology, June 2025, Frontiers

    Dr Javier G Casado

  4. Characterization of preovulatory follicular fluid secretome and its effects on equine oocytes during in vitro maturation

    Article • Research in Veterinary Science, May 2024, Elsevier

    PhD Alfonso Gutierrez-Adan, Dr Javier G Casado

  5. Enhanced expression of natural cytotoxicity receptors on cytokine-induced memory-like natural killer cells correlates with effector function

    Article • Frontiers in Immunology, October 2023, Frontiers

    Dr Javier G Casado

  6. Menstrual blood-derived mesenchymal stromal cells: impact of preconditioning on the cargo of extracellular vesicles as potential therapeutics

    Article • Stem Cell Research & Therapy, July 2023, Springer Science + Business Media

    Dr Javier G Casado

  7. Menstrual blood-derived stromal cells: insights into their secretome in acute hypoxia conditions

    Article • World Journal of Surgery, April 2023, Springer Science + Business Media

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  8. Transcriptome Profile Reveals Differences between Remote and Ischemic Myocardium after Acute Myocardial Infarction in a Swine Model

    Article • Biology, February 2023, MDPI AG

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  9. Intracoronary Administration of Microencapsulated HGF in a Reperfused Myocardial Infarction Swine Model

    Article • Journal of Cardiovascular Development and Disease, February 2023, MDPI AG

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  10. Effects of Cardiac Stem Cell on Postinfarction Arrhythmogenic Substrate

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  11. Isolation, culture and, characterization of Cardiosphere-Derived Cells (CDCs)

    Article • December 2022, Springer Science + Business Media

    Dr Javier G Casado

  12. Isolation, culture and, characterization of endometrial mesenchymal stromal cells (endMSCs)

    Article • December 2022, Springer Science + Business Media

    Dr Javier G Casado

  13. Intrapericardial Administration of Secretomes from Menstrual Blood-Derived Mesenchymal Stromal Cells: Effects on Immune-Related Genes in a Porcine Model of Myocardial Infarction

    Article • Biomedicines, May 2022, MDPI AG

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  14. A Fibrin Coating Method of Polypropylene Meshes Enables the Adhesion of Menstrual Blood-Derived Mesenchymal Stromal Cells: A New Delivery Strategy for Stem Cell-Based Therapies

    Article • International Journal of Molecular Sciences, December 2021, MDPI AG

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  15. The epicardial delivery of cardiosphere derived cells or their extracellular vesicles is safe but of limited value in experimental infarction

    Article • Scientific Reports, November 2021, Springer Science + Business Media

    Dr Javier G Casado

  16. IFN-Gamma and TNF-Alpha as a Priming Strategy to Enhance the Immunomodulatory Capacity of Secretomes from Menstrual Blood-Derived Stromal Cells

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  17. Intrapericardial Delivery of APA-Microcapsules as Promising Stem Cell Therapy Carriers in an Experimental Acute Myocardial Infarction Model

    Article • Pharmaceutics, November 2021, MDPI AG

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  18. Interferon-gamma and TNF-alpha synergistically enhance the immunomodulatory capacity of Endometrial-Derived Mesenchymal Stromal Cell secretomes by differential microRNA and extracellular vesicle release

    Article • June 2021, Cold Spring Harbor Laboratory Press

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  19. Epicardial Delivery of Cardiosphere Derived Cells or Their Extracellular Vesicles in a Relevant Infarcted Swine Model: Safe, Easy but of Limited Effectiveness.

    Article • May 2021, Research Square

    Dr Javier G Casado

  20. Characterization of encapsulated porcine cardiosphere-derived cells embedded in 3D alginate matrices

    Article • International Journal of Pharmaceutics, April 2021, Elsevier

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  21. Natural killer cells in recurrent miscarriage: An overview

    Article • Journal of Reproductive Immunology, November 2020, Elsevier

    Dr Javier G Casado

  22. Laparoscopy for the Treatment of Congenital Hernia: Use of Surgical Meshes and Mesenchymal Stem Cells in a Clinically Relevant Animal Model

    Article • Frontiers in Pharmacology, September 2020, Frontiers

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  23. Hydrogels for Bioprinting: A Systematic Review of Hydrogels Synthesis, Bioprinting Parameters, and Bioprinted Structures Behavior

    Article • Frontiers in Bioengineering and Biotechnology, August 2020, Frontiers

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  24. Characterization of proteins and miRNAs in extracellular vesicles from porcine CDCs

    Article • Frontiers in Cell and Developmental Biology, June 2020, Frontiers

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  25. Multi-layered coating with fibrin glue for surgical meshes ease stem cell adhesion and viability

    Article • BJS, March 2020, Wiley

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  26. IP injection of extracellular vesicles from heart-derived cells is safe after myocardial infarction

    Article • Journal of the American College of Cardiology, March 2020, Elsevier

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  27. Extracellular Vesicles from Cardiosphere-Derived Cells Stimulates M2 Polarization

    Article • Stem Cell Reviews and Reports, February 2020, Springer Science + Business Media

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  28. New stem cell therapy may modulate the unbalanced inflammation in the damaged cardiac tissue.

    Article • Stem Cell Reviews and Reports, December 2019, Springer Science + Business Media

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  29. High-throughput proteomics of extracellular vesicles derived from endometrial Mesenchymal Stem Cells

    Article • Frontiers in Bioengineering and Biotechnology, December 2019, Frontiers

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  30. Method to create a preclinical free skin flap model in rats with ischemia-reperfusion injury.

    Article • Journal of Visualized Experiments, November 2019, MyJove Corporation

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  31. Conditioned serum (CS, “Orthokine”) has been used intra-articularly for osteoarthritic patients

    Article • Frontiers in Pharmacology, June 2019, Frontiers

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  32. Intracoronary administration of allogeneic pig cardiac-derived progenitor cells

    Article • Stem Cell Research & Therapy, May 2019, Springer Science + Business Media

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  33. Peripheral blood lymphocyte alterations may be good biomarkers for predict MI severity

    Article • BMC Veterinary Research, March 2019, Springer Science + Business Media

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  34. Mesenchymal stem cell-based therapies for soft tissue reinforcement.

    Article • Acta Biomaterialia, February 2019, Elsevier

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  35. Analysis of extracellular vesicles from endometrial-derived mesenchymal stem cells

    Article • Biology of Reproduction, December 2018, Oxford University Press (OUP)

    PhD Alfonso Gutierrez-Adan, Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  36. The ischemia-reperfunion injury reduced the survival of free flaps

    Article • PLOS One, December 2018, PLOS

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  37. The immunomodulatory functions mediated by melatonin support its use as vaccine adjuvant.

    Article • Veterinary Immunology and Immunopathology, December 2018, Elsevier

    Dr Javier G Casado

  38. Several blood parameters allowed predict the severity of myocardial infarction in a animal model

    Article • Veterinary Immunology and Immunopathology, November 2018, Elsevier

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  39. EV‐endMSCs increase the developmental competence of IVF‐derived embryos from aged females

    Article • Reproduction in Domestic Animals, September 2018, Wiley

    Dr Francisco Miguel Sánchez Margallo, PhD Alfonso Gutierrez-Adan, Dr Javier G Casado

  40. The endMSCs are multipotent stem cells and exhibit immunomodulatory effects.

    Article • Journal of Tissue Engineering and Regenerative Medicine, August 2018, Wiley

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  41. The percentage flap survival area was significantly higher in the adipose stem cells treated flaps

    Article • Journal of Reconstructive Microsurgery, May 2018, Thieme Publishing Group

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  42. EV-endMSCs may be used as a co-adjuvant to improve in vitro fertilization and embryo quality

    Article • PLOS One, April 2018, PLOS

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  43. Therapeutic effect of MSCs and exosomes combined with FG for the treatment of incisional hernia

    Article • Acta Biomaterialia, April 2018, Elsevier

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  44. Safety and effectiveness of an intracoronary infusion of microencapsulated IGF-1 and HGF.

    Article • European Heart Journal, August 2017, Oxford University Press (OUP)

    Dr Javier G Casado

  45. Immunological evaluation of a clinically relevant model of synovitis

    Article • BMC Veterinary Research, April 2017, Springer Science + Business Media

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  46. Mesenchymal Stem Cell-Derived Exosomes: Immunomodulatory Evaluation in an Antigen-Induced Synovitis

    Article • Frontiers in Veterinary Science, March 2017, Frontiers

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  47. Analysis of bone-marrow derived MSCs and leukocyte from Large White pigs and Göttingen Minipigs

    Article • Veterinary Immunology and Immunopathology, October 2016, Elsevier

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  48. Limitations of natural killer cell-based cancer immunotherapy.

    Article • Medical Oncology, August 2016, Springer Science + Business Media

    Dr Javier G Casado

  49. The improvement in glucose metabolism seems to occur by means of the redistribution of body fat.

    Article • Obesity Surgery, May 2016, Springer Science + Business Media

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  50. Filters for the isolation exosomes could be an alternative to protocols using ultracentrifugation.

    Article • New Biotechnology, May 2016, Elsevier

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  51. Viability, metabolic activity and immunomodulation assays on MSCs-coated meshes

    Article • New Biotechnology, May 2016, Elsevier

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  52. Mesenchymal stem cell derived exosomes in the treatment of synovitis.

    Article • New Biotechnology, May 2016, Elsevier

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  53. Intrapericardial administration of cardiosphere-derived cells may have an immunomodulatory effect

    Article • PLOS One, February 2016, PLOS

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  54. The combined usage of surgical meshes with MSCs, provides an anti-inflammatory environment

    Article • Acta Biomaterialia, February 2016, Elsevier

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  55. Combination of mesenchymal stem cells and biomimetic matrices for cell-based therapies

    Article • Molecular Pharmaceutics, October 2015, American Chemical Society (ACS)

    Dr Javier G Casado

  56. Acute myeloid leukaemia (AML) is generally a disease of older adults

    Article • Medical Oncology, June 2015, Springer Science + Business Media

    Dr Javier G Casado

  57. Administration of cardiac stem cell for acute myocardial infarction could ameliorate remodeling.

    Article • Journal of Translational Medicine, May 2015, Springer Science + Business Media

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  58. Development of canine adipose stem cell lines for the allogeneic treatment of osteoarticular disease

    Article • April 2015, British Small Animal Veterinary Association

    Dr Javier G Casado

  59. Bio-distribution analysis of intrapericardal administration of mesenchymal stem cells

    Article • PLOS One, March 2015, PLOS

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  60. Hemostatic collagen sponge, application and control for gynecological use.

    Article • Journal of Surgical Research, March 2015, Elsevier

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  61. The use of cardiac-derived cell products reported highly promising results with autologous cells.

    Article • Expert Review of Cardiovascular Therapy, February 2015, Taylor & Francis

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  62. Immunomodulatory Potential of Human Adipose Mesenchymal Stem Cells Derived Exosomes

    Article • Frontiers in Immunology, November 2014, Frontiers

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  63. Safety and efficacy assessment of intracoronary delivery of porcine cardiac stem cells

    Article • Journal of the American College of Cardiology, April 2014, Elsevier

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  64. Allogenic cardiac stem cells administration for the treatment of acute Myocardial Infarction

    Article • Journal of the American College of Cardiology, April 2014, Elsevier

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  65. The intrapericardial delivery, an efficient method for pharmacological agent delivery

    Article • Journal of the American College of Cardiology, April 2014, Elsevier

    Dr Javier G Casado, Dr Francisco Miguel Sánchez Margallo

  66. Development of new sutures to improve wound healing

    Article • Wound Repair and Regeneration, March 2014, Wiley

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  67. Cytokine profiles in acute myeloid leukemia patients at diagnosis

    Article • Cytokine, March 2013, Elsevier

    Dr Javier G Casado

  68. MSCs produce specific interactions with immune cells.

    Article • Stem Cell Reviews and Reports, February 2013, Springer Science + Business Media

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  69. TGF-β induce a decrease of NKp30 and not affect the expression of NKp46 and NKG2D.

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr Javier G Casado

  70. MSCs have demonstrated their potentiality for treating diseases or repairing damaged tissues

    Article • Veterinary Immunology and Immunopathology, June 2012, Elsevier

    Dr Francisco Miguel Sánchez Margallo, Dr Javier G Casado

  71. Human adipose-derived stem cells (hASCs) have been successfully used in treating numerous diseases.

    Article • Stem Cells and Development, May 2012, Mary Ann Liebert Inc

    Dr Javier G Casado

  72. Analysis of NK cell-activating receptors and their ligands

    Article • Medical Oncology, June 2011, Springer Science + Business Media

    Dr Javier G Casado

  73. The receptor-ligand crosslinking downregulates DNAM-1 expression on NK cells

    Article • Immunology and Cell Biology, March 2011, Wiley

    Dr Javier G Casado

  74. NK cells are a key component of innate immunity in the regulation of the immune response

    Article • Journal of Innate Immunity, January 2011, Karger Publishers

    Dr Javier G Casado

  75. The majority of melanoma cell lines express ligands for NKG2D

    Article • Journal of Innate Immunity, January 2011, Karger Publishers

    Dr Javier G Casado

  76. Prostasomes are small vesicles secreted by the prostate gland to the seminal fluid.

    Article • Immunobiology, January 2011, Elsevier

    Dr Javier G Casado

  77. The expression of ligands for NK cell activating receptors is variable on different melanoma cells

    Article • Journal of Clinical Investigation, June 2009, American Society for Clinical Investigation

    Dr Javier G Casado

  78. Adhesion molecules and ligands involved in cell-mediated cytotoxicity in a melanoma cell lines

    Article • Medical Oncology, March 2009, Springer Science + Business Media

    Dr Javier G Casado

  79. Effect of ageing on the phenotype and frequency of CMV pp65-specific CD8 T cell subsets

    Article • Immunity & Ageing, January 2009, Springer Science + Business Media

    Dr Javier G Casado

  80. Transfer of antigen-specific CD8+ T cells may represent an strategy for immunotherapy of tumors

    Article • International Immunology, December 2008, Oxford University Press (OUP)

    Dr Javier G Casado

  81. Recombinant lentivectors direct the intracellular synthesis of NY-ESO-1

    Article • European Journal of Immunology, July 2008, Wiley

    Dr Javier G Casado

  82. Functional relevance of HNK-1 expression in metastatic melanoma.

    Article • Tumor Biology, January 2008, Springer Science + Business Media

    Dr Javier G Casado

  83. Remodelling of the CD8 T-Cell Compartment in the Elderly

    Article • January 2007, Springer Science + Business Media

    Dr Javier G Casado

  84. Lymphocyte activation in response to melanoma.

    Article • Medical Oncology, February 2006, Springer Science + Business Media

    Dr Javier G Casado

  85. CD8+ T cells can express NK-associated receptors that may regulate their cytolytic function.

    Article • Medical Oncology, May 2005, Springer Science + Business Media

    Dr Javier G Casado

  86. Natural killer cell–associated receptor

    Article • Medical Oncology, May 2004, Springer Science + Business Media

    Dr Javier G Casado

  87. HIV-1 infected patients show a gradual loss of NK cells that correlates with disease progression

    Article • Journal of Clinical Immunology, January 2002, Springer Science + Business Media

    Dr Javier G Casado

  88. Vα24+ NKT cells are decreased in elderly humans

    Article • Experimental Gerontology, January 2002, Elsevier

    Dr Javier G Casado

  89. NK receptors on CD8 T Lymplhocytes in HIV infected individuals

    Article • AIDS, January 2002, Wolters Kluwer Health

    Dr Javier G Casado

  90. Analysis of expression of CD28 co-stimulatory molecules andNK-Rs

    Article • January 2002, Elsevier

    Dr Javier G Casado

  91. NK Cells in Human Ageing

    Article • Springer Science + Business Media

    Dr Javier G Casado